[Hub]/) : Traits : Blood Eosinophil Count :

chr14:34,645,201-36,571,554

Best TWAS P=8.49e-14 · Best GWAS P=1.56e-25 conditioned to 4.41e-13

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Frontal Cortex BA9 FAM177A1 0.22 0.03 lasso 5 0.06 1.3e-02 -7.8 -5.4 5.5e-08 0.13 0.08 0.07 FALSE
2 GTEx Lung RP11-85K15.2 0.12 0.08 lasso 6 0.06 4.4e-05 6.1 -6.2 4.5e-10 0.16 0.94 0.00 TRUE
3 GTEx Lung RP11-73E17.2 0.09 0.01 lasso 8 0.01 9.9e-02 1.2 5.3 1.2e-07 -0.20 0.35 0.07 FALSE
4 GTEx Muscle Skeletal PSMA6 0.13 0.14 lasso 2 0.12 4.6e-12 6.8 6.8 8.2e-12 -0.23 1.00 0.00 FALSE
5 GTEx Nerve Tibial SRP54 0.16 0.02 enet 14 0.08 1.3e-06 -5.0 -5.1 2.8e-07 0.17 0.76 0.01 FALSE
6 GTEx Testis PPP2R3C 0.23 0.22 lasso 3 0.23 1.6e-10 -4.3 5.6 2.8e-08 -0.12 0.99 0.00 FALSE
7 NTR Blood FAM177A1 0.02 0.00 blup 381 0.01 6.0e-04 2.4 -5.9 3.6e-09 0.33 0.14 0.14 FALSE
8 NTR Blood NFKBIA 0.26 0.09 lasso 10 0.12 3.4e-36 6.3 6.2 7.2e-10 -0.31 1.00 0.00 TRUE
9 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma PPP2R3C 0.19 0.15 lasso 6 0.16 5.0e-18 4.7 5.3 1.2e-07 -0.17 1.00 0.00 FALSE
10 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma KIAA0391 0.09 0.07 enet 6 0.06 8.1e-08 4.3 7.0 3.6e-12 -0.25 0.97 0.02 FALSE
11 The Cancer Genome Atlas Lung Adenocarcinoma KIAA0391 0.06 0.06 lasso 2 0.04 2.5e-05 4.3 5.3 1.5e-07 -0.19 0.87 0.03 FALSE
12 The Cancer Genome Atlas Stomach Adenocarcinoma PPP2R3C 0.06 0.06 blup 51 0.06 6.4e-05 4.2 5.5 3.5e-08 -0.16 0.28 0.35 FALSE
13 The Cancer Genome Atlas Testicular Germ Cell Tumors PSMA6 0.17 0.00 blup 52 0.05 8.0e-03 2.5 7.5 8.5e-14 -0.24 0.01 0.38 TRUE