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chr19:36,282,543-38,725,416

Best TWAS P=3.62e-11 · Best GWAS P=2.05e-11 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ZNF420	0.06	0.07	lasso	1	0.07	6.3e-09	-6.4	6.4	1.7e-10	-0.93	0.06	0.94	FALSE
2	CommonMind	Brain Pre-frontal Cortex	ZNF585A	0.08	0.10	lasso	3	0.11	2.6e-13	-6.5	6.4	1.3e-10	-0.96	0.02	0.98	FALSE
3	GTEx	Adipose Subcutaneous	ZNF585A	0.09	0.02	lasso	3	0.02	3.8e-03	-6.0	-6.3	2.8e-10	0.91	0.13	0.68	FALSE
4	GTEx	Adipose Visceral Omentum	ZNF585B	0.06	0.02	enet	8	0.00	2.5e-01	-5.7	-5.4	7.3e-08	0.76	0.10	0.30	FALSE
5	GTEx	Artery Aorta	ZNF829	0.11	0.04	lasso	2	0.00	2.5e-01	-5.7	5.9	3.3e-09	-0.76	0.10	0.42	FALSE
6	GTEx	Artery Aorta	ZNF568	0.14	0.11	lasso	8	0.10	6.0e-06	-5.7	5.4	7.4e-08	-0.92	0.05	0.95	FALSE
7	GTEx	Artery Tibial	ZNF585B	0.17	0.14	lasso	15	0.22	5.6e-17	-6.7	-5.9	4.6e-09	0.89	0.04	0.96	FALSE
8	GTEx	Artery Tibial	ZNF260	0.09	0.02	lasso	8	0.02	9.5e-03	2.5	-5.7	1.2e-08	0.76	0.02	0.94	FALSE
9	GTEx	Brain Cerebellum	ZNF793	0.23	0.02	enet	40	0.07	4.8e-03	-5.7	5.8	5.5e-09	-0.69	0.04	0.67	FALSE
10	GTEx	Heart Atrial Appendage	ZNF850	0.08	0.03	enet	15	0.06	1.6e-03	-6.6	5.4	6.1e-08	-0.86	0.02	0.92	FALSE
11	GTEx	Lung	ZNF585B	0.06	0.08	lasso	5	0.07	7.0e-06	6.2	-5.9	3.3e-09	0.63	0.45	0.52	FALSE
12	GTEx	Nerve Tibial	ZNF585A	0.06	0.07	lasso	9	0.06	6.9e-05	-5.7	-5.8	6.0e-09	0.75	0.58	0.36	FALSE
13	GTEx	Pituitary	CTD-2630F21.1	0.14	0.02	lasso	7	-0.01	4.6e-01	5.6	-5.4	7.6e-08	0.69	0.07	0.12	FALSE
14	GTEx	Spleen	ZNF585A	0.23	0.10	lasso	8	0.07	5.9e-03	-5.6	-5.6	2.2e-08	0.81	0.08	0.54	FALSE
15	GTEx	Stomach	ZNF585B	0.07	0.07	lasso	5	0.05	1.4e-03	-5.8	-5.9	3.1e-09	0.75	0.26	0.35	FALSE
16	GTEx	Thyroid	ZNF585B	0.04	0.03	lasso	6	0.01	4.0e-02	5.6	-5.6	1.7e-08	0.71	0.14	0.47	FALSE
17	GTEx	Whole Blood	HKR1	0.07	0.01	lasso	8	0.02	5.1e-03	-4.4	5.3	1.4e-07	-0.78	0.43	0.23	FALSE
18	NTR	Blood	ZNF260	0.03	0.02	blup	321	0.03	1.3e-09	-6.7	6.6	4.7e-11	-0.78	0.01	0.99	FALSE
19	The Cancer Genome Atlas	Breast Invasive Carcinoma	ZNF568	0.01	0.01	blup	64	0.01	1.3e-03	-5.7	6.6	3.7e-11	-0.93	0.02	0.92	FALSE
20	The Cancer Genome Atlas	Colon Adenocarcinoma	ZNF585A	0.08	0.06	blup	29	0.05	5.0e-04	-6.5	5.3	8.7e-08	-0.89	0.00	0.97	FALSE
21	The Cancer Genome Atlas	Glioblastoma Multiforme	ZNF568	0.15	0.12	lasso	3	0.10	4.5e-04	-6.6	6.1	8.9e-10	-0.96	0.02	0.80	FALSE
22	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	ZNF568	0.12	0.07	blup	62	0.07	1.3e-03	-5.7	5.4	7.8e-08	-0.88	0.02	0.83	FALSE
23	The Cancer Genome Atlas	Prostate Adenocarcinoma	ZNF585B	0.12	0.04	enet	9	0.07	5.6e-08	-5.6	-6.2	4.3e-10	0.76	0.03	0.97	FALSE
24	The Cancer Genome Atlas	Thyroid Carcinoma	ZNF568	0.20	0.14	lasso	2	0.14	9.3e-14	-6.6	6.6	3.6e-11	-0.97	0.01	0.99	TRUE