[Hub]/) : Traits : Lung FVC : ← →

chr10:69,293,282-71,273,696

Best TWAS P=3.37e-16 · Best GWAS P=6.76e-31 conditioned to 6.59e-07

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ATOH7	0.10	0.08	lasso	10	0.09	4.3e-11	6.1	-6.2	5.3e-10	0.55	1.00	0.00	FALSE
2	GTEx	Artery Aorta	PBLD	0.14	0.10	lasso	8	0.06	3.1e-04	5.0	5.5	3.2e-08	-0.43	0.97	0.01	FALSE
3	GTEx	Brain Caudate basal ganglia	PBLD	0.17	0.14	lasso	16	0.13	1.2e-04	5.0	6.3	2.5e-10	-0.48	0.62	0.07	FALSE
4	GTEx	Brain Frontal Cortex BA9	PBLD	0.15	0.00	lasso	3	0.01	1.6e-01	5.0	5.7	1.2e-08	-0.43	0.28	0.17	FALSE
5	GTEx	Brain Hypothalamus	SLC25A16	0.20	0.19	lasso	5	0.14	3.6e-04	5.0	5.5	3.7e-08	-0.36	0.12	0.28	FALSE
6	GTEx	Esophagus Muscularis	RUFY2	0.06	0.02	lasso	6	0.02	2.0e-02	5.5	5.8	7.7e-09	-0.43	0.18	0.04	FALSE
7	GTEx	Heart Atrial Appendage	PBLD	0.08	0.02	lasso	2	0.02	6.1e-02	4.7	6.1	9.5e-10	-0.47	0.07	0.44	FALSE
8	GTEx	Muscle Skeletal	PBLD	0.11	0.10	lasso	12	0.12	5.1e-12	6.0	6.3	3.5e-10	-0.48	1.00	0.00	FALSE
9	GTEx	Skin Not Sun Exposed Suprapubic	DNA2	0.29	0.16	lasso	14	0.22	2.4e-12	4.4	-5.2	1.8e-07	0.33	1.00	0.00	FALSE
10	METSIM	Adipose	PBLD	0.16	0.15	lasso	12	0.14	6.4e-21	5.0	5.5	5.0e-08	-0.41	1.00	0.00	TRUE
11	ROSMAP	Brain Pre-frontal Cortex	PBLD	0.04	0.01	bslmm	388	0.02	1.3e-03	5.7	7.1	1.6e-12	-0.55	0.75	0.22	FALSE
12	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	PBLD	0.06	0.07	lasso	2	0.04	2.3e-04	6.4	6.4	1.6e-10	-0.44	0.01	0.98	FALSE
13	The Cancer Genome Atlas	Breast Invasive Carcinoma	PBLD	0.03	0.01	enet	6	0.02	2.9e-05	5.0	5.2	1.7e-07	-0.40	0.70	0.30	FALSE
14	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	ATOH7	0.05	0.01	lasso	3	0.02	2.6e-03	6.6	-6.5	1.1e-10	0.45	0.04	0.05	FALSE
15	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	PBLD	0.03	0.03	lasso	9	0.02	1.6e-03	6.8	6.9	5.5e-12	-0.53	0.01	0.93	FALSE
16	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ATOH7	0.16	0.06	enet	15	0.09	3.7e-10	5.7	-5.4	7.0e-08	0.45	0.99	0.00	FALSE
17	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	MYPN	0.05	0.06	lasso	5	0.05	6.4e-06	6.3	6.2	5.2e-10	-0.58	0.37	0.63	FALSE
18	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PBLD	0.10	0.03	lasso	3	0.04	2.2e-05	6.4	6.1	8.0e-10	-0.44	0.02	0.98	FALSE
19	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	ATOH7	0.08	0.04	enet	19	0.06	3.1e-04	5.7	-8.2	3.4e-16	0.67	0.12	0.54	TRUE
20	The Cancer Genome Atlas	Brain Lower Grade Glioma	PBLD	0.12	0.18	enet	10	0.18	6.7e-20	5.0	5.6	2.3e-08	-0.40	0.40	0.60	FALSE
21	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	PBLD	0.02	0.01	blup	76	0.01	1.5e-02	5.0	5.7	9.5e-09	-0.44	0.15	0.23	FALSE
22	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	ATOH7	0.10	-0.01	blup	59	0.04	1.1e-02	5.7	-7.4	1.7e-13	0.63	0.04	0.16	FALSE
23	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	HKDC1	0.17	0.04	lasso	5	0.07	6.0e-04	6.1	6.2	6.0e-10	-0.16	0.00	0.99	TRUE
24	The Cancer Genome Atlas	Prostate Adenocarcinoma	ATOH7	0.02	0.01	lasso	3	0.00	1.3e-01	6.0	-6.2	6.6e-10	0.47	0.10	0.03	FALSE
25	The Cancer Genome Atlas	Prostate Adenocarcinoma	PBLD	0.03	0.01	blup	76	0.01	1.3e-02	5.9	6.3	3.4e-10	-0.47	0.05	0.43	FALSE
26	The Cancer Genome Atlas	Stomach Adenocarcinoma	ATOH7	0.05	0.05	lasso	2	0.05	8.6e-05	5.3	-6.3	3.9e-10	0.59	0.11	0.49	FALSE
27	The Cancer Genome Atlas	Testicular Germ Cell Tumors	DNA2	0.14	0.07	blup	43	0.08	8.6e-04	5.2	5.2	2.5e-07	-0.32	0.01	0.93	FALSE
28	The Cancer Genome Atlas	Thyroid Carcinoma	HKDC1	0.14	0.11	lasso	6	0.14	8.2e-14	3.9	5.4	6.3e-08	-0.08	0.33	0.67	FALSE