Hub : Genes

OMG

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Cells Transformed fibroblasts	0.0620	0.0320	8.7e-03	0.024	NA	0.006	NA	0.015	6.4e-03	NA	1.1e-01	NA	2.5e-02
2	GTEx	Spleen	0.4110	0.1140	2.4e-06	0.099	NA	0.079	NA	0.076	1.7e-03	NA	4.5e-03	NA	5.4e-03
3	TCGA	Bladder Urothelial Carcinoma	0.0240	0.0170	2.6e-03	0.019	0.025	0.020	NA	0.018	9.4e-03	3.2e-03	8.0e-03	NA	1.0e-02
4	TCGA	Breast Invasive Carcinoma	0.0321	0.0198	5.9e-08	0.040	0.040	0.031	NA	0.040	9.5e-09	1.3e-08	3.7e-07	NA	1.1e-08
5	TCGA	Esophageal Carcinoma	0.0860	0.0560	5.7e-04	0.087	0.113	0.098	NA	0.091	1.0e-03	2.0e-04	5.1e-04	NA	8.1e-04
6	TCGA	Kidney Renal Clear Cell Carcinoma	0.0228	0.0169	7.4e-04	0.018	0.025	0.016	NA	0.018	3.5e-03	6.9e-04	5.1e-03	NA	3.9e-03
7	TCGA	Lung Adenocarcinoma	0.0491	0.0411	1.8e-04	0.031	0.031	0.036	NA	0.037	1.3e-04	1.3e-04	4.2e-05	NA	3.7e-05
8	TCGA	Ovarian Serous Cystadenocarcinoma	0.0520	0.0460	7.0e-03	0.029	0.027	-0.003	NA	0.022	4.6e-03	5.6e-03	6.1e-01	NA	1.2e-02
9	TCGA	Thyroid Carcinoma	0.0220	0.0160	1.9e-03	0.014	0.019	0.012	NA	0.011	1.4e-02	4.8e-03	2.0e-02	NA	2.7e-02

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	0.1	0.2	0.4	0.1	0.2	-0.6	0.0	-0.4	-0.5	-0.2	0.4	-0.6
Bipolar Disorder or Schizophrenia	0.3	0.6	1.3	-0.7	-1.0	0.5	1.0	0.7	0.6	0.6	1.1	0.5
Depressed Affect (Nagel 2018)	0.2	0.4	1.1	-0.2	0.0	-0.8	-0.3	-0.7	-0.7	-1.0	0.1	-0.7
Depression (Nagel 2018)	0.0	0.1	0.5	0.2	-0.1	0.1	-0.1	0.0	0.1	0.7	-0.3	0.0
Intelligence (Savage-Jansen 2018)	3.4	10.3	12.6	3.4	2.1	-3.3	-3.5	-3.4	-3.3	-2.7	-3.6	-3.3
Neuroticism (Nagel 2018)	0.5	1.3	2.0	0.6	1.3	-1.1	-1.2	-1.2	-1.2	-1.4	-0.8	-1.2
Schizophrenia (2018)	0.7	1.4	2.3	-1.0	-1.5	1.2	1.3	1.2	1.2	1.1	1.2	1.2
Schizophrenia vs Biploar Disorder	0.6	0.8	1.1	-0.7	-0.9	1.1	0.6	0.9	1.0	1.0	0.4	1.0
Worry (Nagel 2018)	2.9	6.0	13.5	1.9	3.7	-2.1	-2.6	-2.3	-2.3	-2.2	-2.3	-2.4
Alzheimer’s Disease (in mother)	0.9	1.1	1.6	1.3	0.9	-0.9	-1.0	-1.0	-1.0	-1.0	-1.2	-1.0
Alzheimer’s Disease (in father)	0.1	0.1	0.3	0.2	0.6	0.3	-0.4	0.1	0.1	0.3	-0.6	0.1
Alzheimer’s Disease (including proxy)	2.0	3.0	4.3	1.9	1.7	-1.5	-1.9	-1.7	-1.6	-1.5	-2.1	-1.7
Crohns Disease (2017)	0.3	0.6	0.9	0.7	0.9	-0.8	-0.8	-0.9	-0.7	0.7	-0.6	-0.8
Irritable Bowel Disease (IBD)	0.1	0.2	0.9	0.2	0.9	-0.3	-0.1	-0.3	-0.2	0.7	0.1	-0.3
Ulcerative Colitis (UC)	0.1	0.2	0.4	-0.4	0.6	0.3	0.5	0.4	0.4	0.5	0.6	0.3
Major Depression (MDD)	0.0	0.1	0.2	-0.3	-0.2	0.1	0.1	0.1	0.1	0.5	0.4	0.1
Reaction Time	0.8	1.5	2.4	1.2	1.3	-1.3	-1.3	-1.4	-1.4	-0.6	-0.9	-1.6
Verbal and Numeric Reasoning (VNR)	3.2	7.6	9.2	2.9	2.4	-2.8	-3.0	-2.9	-2.8	-2.2	-3.0	-2.8
Breast Cancer	2.5	5.9	8.6	-2.1	-2.8	2.3	2.9	2.5	2.4	1.4	2.7	2.4
Ovarian Cancer	0.4	0.5	0.9	-1.0	-0.9	0.4	0.7	0.5	0.5	0.8	0.9	0.6
Prostate Cancer	0.0	0.1	0.4	-0.0	0.7	0.2	-0.1	0.1	0.1	0.0	-0.3	0.1
Age at First Birth	4.0	5.8	6.7	2.5	1.7	-2.5	-2.5	-2.5	-2.5	-2.4	-2.6	-2.5
Bipolar Disorder (2011)	3.9	3.8	5.9	0.0	0.0	-2.3	-2.2	-2.3	-2.3	-2.0	-1.8	-2.4
Body Mass Index (BMI) (2010)	4.9	6.7	7.5	2.7	2.7	-2.6	-2.6	-2.7	-2.6	-2.1	-2.5	-2.7
Coronary Artery Disease (CAD)	0.3	0.3	2.4	0.1	-1.6	0.2	0.4	0.3	0.3	-0.3	0.0	0.3
Crohns Disease (2012)	0.9	1.4	1.5	1.2	1.2	-1.1	-1.2	-1.2	-1.2	-1.1	-1.2	-1.2
Mean Putamen Volume	4.6	5.3	6.3	-2.2	-2.1	2.4	2.2	2.4	2.4	2.5	2.0	2.5
Fasting Glucose	0.7	0.8	1.6	0.7	0.3	-1.1	-0.5	-1.0	-1.1	-1.3	-0.3	-1.1
HbA1C	3.4	3.8	5.2	-1.8	-1.5	2.3	1.8	2.1	2.2	2.3	1.4	2.0
HDL Cholesterol	0.6	1.0	2.2	-0.7	-0.1	1.5	0.3	1.1	1.3	1.3	0.0	1.2
LDL Cholesterol	3.5	5.6	10.2	-1.9	-3.2	2.1	2.3	2.2	2.3	2.6	2.1	2.3
Lupus	1.9	2.8	3.7	1.7	1.9	-1.7	-1.6	-1.7	-1.7	-1.3	-1.7	-1.7
Neuroticism (2016)	1.4	2.0	2.4	1.3	1.5	-1.5	-1.4	-1.5	-1.5	-1.4	-1.1	-1.6
Primary Biliary Cirrhosis	0.5	0.8	1.4	0.7	0.9	-0.8	-1.2	-0.9	-0.8	-0.1	-1.0	-0.9
Rheumatoid Arthritis	0.2	0.3	1.5	0.0	-0.2	-0.6	-0.1	-0.4	-0.5	-1.2	-0.0	-0.4
Schizophrenia (2014)	0.1	0.3	0.7	-0.2	-0.8	0.5	0.5	0.6	0.5	0.4	0.5	0.5
Triglycerides	0.1	0.2	0.8	-0.5	-0.5	-0.0	0.7	0.2	0.1	0.0	0.9	0.2
Type 2 Diabetes (T2D) (2012)	0.6	0.6	1.4	0.5	0.7	-1.1	-0.2	-0.8	-0.9	-1.2	0.1	-0.9
Ulcerative Colitis	0.0	0.1	0.3	0.1	0.5	0.2	0.0	0.2	0.2	0.4	0.1	0.1
Blood Eosinophil Count	0.5	4.0	6.2	-1.3	-2.5	2.2	1.6	2.0	2.2	2.5	1.1	2.1
Blood Platelet Count	8.5	98.7	118.8	-9.3	-8.3	10.9	9.8	10.8	10.9	9.6	8.7	10.8
Blood Red Count	1.1	10.3	12.5	-3.4	-3.5	2.8	3.4	3.0	3.0	3.2	3.5	3.1
Blood White Count	0.3	2.5	4.3	-1.3	-0.2	2.0	1.3	1.8	1.9	2.1	1.0	1.8
Heel T-Score	0.1	1.1	4.2	-0.8	-2.0	0.3	1.2	0.6	0.4	-0.9	1.2	0.6
BMI	1.4	8.2	9.5	3.0	2.6	-3.1	-2.5	-3.0	-3.0	-2.9	-2.6	-3.0
Height	7.4	142.1	166.4	12.4	12.3	-11.4	-12.9	-12.2	-11.9	-8.9	-12.5	-12.3
Waist Hip Ratio (WHR)	4.2	19.1	20.6	-4.5	-3.9	4.4	4.5	4.5	4.5	4.1	4.4	4.5
Systolic Blood Pressure	0.1	0.4	1.4	0.2	1.2	-0.6	-0.7	-0.6	-0.5	0.5	-0.3	-0.6
Smoking Status	1.9	4.6	5.7	-1.7	-2.4	2.2	2.2	2.3	2.3	1.9	1.8	2.3
Allergy or Eczema	4.0	10.5	14.1	3.0	2.1	-3.8	-3.2	-3.6	-3.6	-3.2	-2.7	-3.5
Cardiovascular Disease	0.2	0.7	1.6	0.2	0.2	-1.2	-0.5	-1.0	-1.1	-1.2	-0.0	-1.0
Hypothyroidism (self reported)	0.0	0.0	0.2	-0.0	-0.1	0.1	0.2	0.2	0.2	0.4	0.2	0.1
Respiratory disease	0.1	0.1	0.4	-0.2	-0.6	0.1	0.5	0.3	0.2	-0.4	0.6	0.2
Type 2 Diabetes (T2D) (2018)	3.7	6.8	9.9	1.9	2.1	-3.1	-2.3	-2.9	-3.0	-3.0	-1.7	-2.9
Lung FEV1/FVC ratio	0.0	0.1	0.5	0.7	-0.2	-0.1	-0.4	-0.1	-0.1	0.5	-0.6	-0.1
Lung FVC	4.8	24.2	33.3	-4.4	-5.8	5.4	4.5	5.2	5.2	4.4	3.8	5.3
Neuroticism	0.4	1.0	1.6	0.3	1.2	-1.1	-1.0	-1.1	-1.1	-1.3	-0.5	-1.1
Chronotype (morning person)	0.1	0.2	0.4	0.6	0.1	-0.4	-0.5	-0.4	-0.4	0.1	-0.5	-0.5
Hair Pigment	0.0	0.4	1.2	-1.0	-0.7	-0.2	0.6	0.1	-0.1	-0.9	1.1	0.1
Tanning	0.2	2.4	3.1	-1.1	-1.6	1.8	1.6	1.7	1.7	1.7	1.2	1.6
Hand grip strength (left)	0.3	0.8	2.5	0.7	1.6	-0.9	-0.8	-0.9	-0.8	0.2	-0.4	-1.0
Number of treatments/medications taken	0.7	1.3	2.6	0.9	0.2	-1.4	-0.9	-1.3	-1.3	-1.6	-0.7	-1.3
Average weekly spirits intake	0.6	0.7	1.8	-1.2	-0.9	0.4	1.1	0.6	0.5	-0.1	1.3	0.6
Sensitivity / hurt feelings	1.6	2.8	3.4	-1.7	-1.8	1.6	1.8	1.7	1.7	1.1	1.8	1.7
Frequency of depressed mood in last 2 weeks	0.3	0.4	0.5	0.6	0.5	-0.7	-0.6	-0.7	-0.7	-0.3	-0.5	-0.7
Hearing difficulty/problems: Yes	1.6	2.5	2.9	-1.7	-1.7	1.6	1.7	1.6	1.6	1.0	1.6	1.6
Relative age of first facial hair	4.1	8.4	12.2	-3.5	-2.7	2.8	3.0	3.0	2.8	1.9	3.3	2.9
Other serious medical condition/disability diagnosed by doctor	0.1	0.1	0.3	-0.2	-0.3	-0.4	-0.0	-0.3	-0.3	-0.5	0.2	-0.3
Ever used hormone-replacement therapy (HRT)	0.0	0.0	0.1	0.3	-0.1	0.2	0.1	0.1	0.1	0.2	-0.1	-0.0
Ever had hysterectomy (womb removed)	0.1	0.1	1.0	0.1	-0.0	-0.0	-0.2	-0.1	-0.0	1.0	-0.1	-0.1
Systolic blood pressure, automated reading	0.4	1.1	1.6	1.0	1.3	-1.1	-0.9	-1.1	-1.1	-0.6	-0.7	-1.2
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.3	0.4	0.4	-0.5	-0.5	-0.5	-0.5	-0.5	-0.4	-0.5
Angina	1.1	1.5	2.0	-1.1	-0.8	1.3	1.1	1.3	1.3	1.4	1.0	1.3
Medication for hormone replacement therapy	0.7	0.8	1.9	-0.6	-0.4	1.2	0.6	1.0	1.0	1.4	0.5	0.9
Vitamin and mineral supplements	1.0	1.3	3.4	0.9	1.1	-1.3	-0.8	-1.1	-1.2	-1.8	-0.6	-1.2
Supplements: Zinc	3.9	4.3	5.2	-2.0	-1.6	2.3	1.9	2.2	2.2	2.3	1.8	2.2
Medication: Co-codamol	4.7	5.4	11.9	1.5	1.6	-2.6	-2.0	-2.5	-2.6	-3.4	-1.7	-2.4
Medication: Metformin	1.1	1.5	3.0	0.6	0.8	-1.6	-0.9	-1.4	-1.4	-1.7	-0.6	-1.3
Diabetes (father)	0.8	1.0	3.1	0.8	1.7	-0.8	-0.9	-0.8	-0.9	-0.9	-0.8	-0.9
Diabetes (mother)	3.2	4.0	5.3	2.0	1.4	-2.3	-1.7	-2.1	-2.2	-2.3	-1.5	-2.2
Severe depression (siblings)	4.8	5.4	9.2	1.8	2.1	-2.8	-1.7	-2.5	-2.6	-3.0	-1.2	-2.6
Pack years adult smoking proportion	0.1	0.1	0.2	-0.3	0.5	0.4	0.4	0.4	0.4	0.2	0.2	0.4
Impedance of leg (right)	4.0	19.4	23.2	-4.4	-3.4	4.6	4.3	4.6	4.6	4.8	4.4	4.5
Leg fat-free mass (left)	9.0	47.7	52.7	7.0	6.1	-7.2	-7.0	-7.3	-7.2	-6.3	-6.8	-7.2
Trunk fat percentage	0.4	1.5	2.2	1.5	0.5	-1.4	-0.9	-1.2	-1.3	-1.4	-1.1	-1.3
Hand grip strength (right)	0.3	0.8	3.3	0.6	1.8	-0.8	-0.7	-0.9	-0.9	0.0	-0.3	-1.0
Townsend deprivation index at recruitment	0.1	0.2	0.5	-0.7	-0.7	0.2	0.2	0.3	0.3	0.7	0.3	0.3
Current tobacco smoking	0.1	0.1	0.4	-0.2	-0.3	0.0	0.3	0.1	0.1	-0.6	0.2	0.2
Average weekly fortified wine intake	0.1	0.2	0.4	0.1	0.3	0.6	0.2	0.5	0.5	0.5	-0.1	0.5
Maternal smoking around birth	2.0	2.9	4.3	-2.1	-1.5	1.5	1.9	1.7	1.6	1.0	2.1	1.7
Fed-up feelings	0.9	1.6	3.7	0.6	1.0	-1.5	-0.9	-1.4	-1.5	-1.9	-0.4	-1.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.9	1.1	1.5	1.2	0.7	-1.1	-1.2	-1.2	-1.1	-0.3	-1.2	-1.2
Relative age voice broke	1.4	2.1	3.5	-1.9	-1.6	1.2	1.5	1.4	1.3	0.4	1.8	1.4
Taking other prescription medications	0.1	0.2	0.5	0.5	0.7	-0.1	-0.4	-0.2	-0.2	-0.3	-0.6	-0.3
Age when periods started (menarche)	0.1	0.1	0.2	-0.4	-0.3	0.4	0.4	0.4	0.4	-0.0	0.4	0.4
Bilateral oophorectomy (both ovaries removed)	0.0	0.0	0.1	0.3	-0.1	-0.2	-0.0	-0.2	-0.2	0.0	-0.1	-0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.4	1.8	-0.3	-0.0	-0.8	-0.0	-0.5	-0.7	-1.3	0.5	-0.7
Tinnitus: Yes, but not now, but have in the past	0.9	1.0	2.0	-0.8	-1.4	1.0	1.1	1.1	1.0	0.5	0.9	1.1
Qualifications: CSEs or equivalent	0.2	0.3	0.9	-0.5	0.5	0.3	0.8	0.5	0.4	0.6	0.9	0.4
Serious illness, injury or assault to yourself	0.9	1.1	1.7	0.7	0.6	-1.3	-1.0	-1.2	-1.2	-1.3	-0.8	-1.1
High blood pressure	1.1	3.1	5.1	1.1	1.4	-2.3	-1.5	-2.0	-2.1	-2.0	-0.8	-2.0
Hayfever, allergic rhinitis or eczema	3.4	7.4	9.2	2.6	1.9	-3.0	-2.8	-3.0	-3.0	-2.5	-2.6	-2.9
Multivitamins +/- minerals	0.9	1.2	3.1	-0.7	-1.2	1.2	0.8	1.1	1.2	1.7	0.6	1.1
Stomach or abdominal pain in last month	4.4	5.4	7.2	-2.1	-2.1	2.5	2.3	2.4	2.5	2.7	2.1	2.4
Supplements: Glucosamine	5.2	6.8	8.2	2.9	2.7	-2.5	-2.7	-2.6	-2.6	-2.0	-2.6	-2.7
Diverticular disease/diverticulitis (self-reported)	1.8	2.2	3.8	-0.9	-1.9	2.0	0.7	1.6	1.7	1.6	0.0	1.7
Medication: Atenolol	0.8	1.0	1.3	0.8	0.8	-1.1	-0.9	-1.1	-1.1	-1.0	-0.7	-1.1
Medication: Levothyroxine sodium	0.0	0.0	0.0	0.1	-0.0	-0.1	0.0	-0.0	-0.0	0.1	0.0	-0.1
Sitting height	2.5	17.7	23.8	4.5	3.8	-4.0	-4.9	-4.4	-4.2	-2.4	-4.8	-4.3
Chronic bronchitis/emphysema (father)	1.7	2.0	2.6	-1.6	-1.2	1.3	1.5	1.4	1.4	1.4	1.6	1.4
High blood pressure (mother)	0.9	1.3	2.9	1.2	1.7	-1.1	-1.1	-1.1	-1.1	-0.2	-0.9	-1.2
Body mass index (BMI)	1.9	8.1	12.7	2.8	1.8	-3.3	-2.3	-3.0	-3.2	-3.6	-2.2	-3.0
Impedance of leg (left)	3.6	17.4	20.4	-4.3	-3.2	4.3	4.1	4.3	4.3	4.5	4.3	4.2
Leg predicted mass (left)	9.3	49.2	54.5	7.1	6.2	-7.3	-7.1	-7.4	-7.3	-6.5	-6.9	-7.3
Trunk fat mass	2.6	11.2	13.0	3.5	2.6	-3.6	-3.2	-3.5	-3.6	-3.3	-3.1	-3.5
Waist circumference	2.7	9.8	13.2	3.0	2.3	-3.6	-2.6	-3.4	-3.5	-3.6	-2.4	-3.4
Number of incorrect matches in round	0.1	0.2	0.4	0.1	-0.7	0.4	-0.1	0.3	0.4	0.6	-0.3	0.3
Past tobacco smoking	1.1	2.1	2.7	1.2	1.7	-1.6	-1.4	-1.6	-1.6	-1.1	-1.1	-1.6
Alcohol usually taken with meals	0.1	0.1	0.3	0.1	0.5	-0.6	-0.2	-0.4	-0.5	-0.2	0.1	-0.5
Nervous feelings	6.6	12.4	18.5	3.0	4.3	-3.4	-3.6	-3.5	-3.5	-3.4	-3.2	-3.6
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.3	3.5	-1.3	-0.2	1.2	0.7	1.0	1.1	1.9	1.0	1.0
Hearing difficulty/problems with background noise	1.6	2.6	3.3	-1.8	-1.3	1.6	1.6	1.7	1.6	1.4	1.7	1.6
Hair/balding pattern: Pattern 2	0.5	0.7	1.5	1.1	1.2	-0.5	-0.9	-0.7	-0.6	0.1	-0.9	-0.8
Had menopause	0.1	0.1	0.3	-0.2	-0.1	0.3	0.5	0.4	0.4	0.4	0.6	0.3
Had other major operations	0.4	0.5	0.7	-0.8	-0.4	0.7	0.8	0.7	0.7	0.5	0.8	0.8
Forced vital capacity (FVC)	0.1	0.3	1.3	-0.0	0.1	0.6	-0.4	0.3	0.4	1.1	-0.6	0.4
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.2	0.8	-0.5	-0.7	-0.2	0.4	-0.0	-0.2	-0.9	0.6	-0.1
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	1.4	-0.6	-0.7	0.0	0.6	0.2	0.1	-1.2	0.7	0.2
Qualifications: None of the above	0.3	0.7	1.9	-0.9	-1.4	0.1	1.0	0.4	0.2	-0.9	1.2	0.4
Financial difficulties in last 2 years	0.1	0.2	0.5	-0.6	-0.7	0.2	0.4	0.3	0.2	-0.1	0.6	0.3
Mouth/teeth dental problems	0.3	0.5	2.5	0.6	1.6	0.5	-0.3	0.2	0.3	0.8	-0.8	0.2
Heart attack	0.2	0.3	0.6	0.5	0.2	-0.6	-0.4	-0.6	-0.6	-0.8	-0.5	-0.5
Allergy	0.6	1.3	1.8	-1.3	-0.5	1.2	1.3	1.2	1.2	0.8	1.3	1.2
Pain all over the body in last month	0.4	0.4	1.5	0.5	-0.2	-0.7	-0.5	-0.6	-0.7	-1.2	-0.5	-0.6
Diabetes (self-reported)	1.6	2.5	4.2	1.1	1.1	-2.1	-1.3	-1.8	-1.9	-1.9	-0.8	-1.8
Hayfever/allergic rhinitis (self-reported)	0.0	0.0	0.1	0.1	0.2	-0.0	-0.1	-0.0	-0.0	-0.3	-0.2	0.0
Medication: Ramipril	0.2	0.2	0.6	-0.1	-0.0	-0.8	0.0	-0.5	-0.6	-0.8	0.4	-0.5
Medication: Simvastatin	0.3	0.4	1.4	-0.8	-1.2	0.2	0.7	0.4	0.2	-0.8	0.7	0.4
Fluid intelligence score	1.5	3.2	4.0	1.9	1.3	-1.8	-2.0	-1.9	-1.8	-1.4	-2.0	-1.8
Illnesses of siblings	0.8	1.1	2.0	-1.4	0.2	1.1	1.0	1.1	1.1	0.6	1.2	1.1
Neuroticism score	0.5	1.1	1.7	0.4	1.3	-1.1	-1.0	-1.1	-1.2	-1.3	-0.5	-1.2
Weight	7.5	37.1	42.8	6.1	5.2	-6.5	-5.9	-6.5	-6.5	-5.8	-5.7	-6.4
Impedance of arm (right)	4.4	20.7	26.0	-4.2	-3.8	5.1	4.2	4.9	5.0	4.8	3.8	4.9
Arm fat percentage (right)	0.1	0.5	1.8	0.7	-0.5	-0.9	-0.1	-0.6	-0.7	-1.4	-0.3	-0.6
Trunk fat-free mass	11.4	65.5	72.9	8.1	7.7	-8.4	-8.3	-8.5	-8.4	-6.9	-7.9	-8.5
Hip circumference	10.4	44.8	50.2	6.7	5.9	-7.1	-6.4	-7.0	-7.1	-6.7	-6.2	-7.0
Time employed in main current job	0.1	0.1	0.5	0.5	0.4	0.3	-0.4	0.0	0.1	0.3	-0.7	0.0
Alcohol intake versus 10 years previously	0.3	0.5	2.4	-0.2	-1.6	-0.8	0.3	-0.4	-0.5	-0.6	0.7	-0.4
Father’s age at death	0.0	0.0	0.1	0.3	0.2	-0.2	-0.2	-0.2	-0.2	-0.2	-0.1	-0.3
Worrier / anxious feelings	1.5	2.8	5.3	1.4	2.3	-1.3	-1.7	-1.5	-1.5	-1.8	-1.7	-1.6
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.4	0.7	0.5	0.1	-0.9	-0.5	-0.7	-0.8	-0.6	-0.3	-0.7
Falls in the last year	0.1	0.2	1.3	0.1	1.1	-0.1	-0.2	-0.2	-0.1	-0.4	-0.3	-0.1
Hair/balding pattern: Pattern 3	0.2	0.3	0.7	0.0	0.6	-0.8	-0.4	-0.6	-0.7	-0.8	0.0	-0.7
Number of live births	2.3	3.3	3.8	-1.7	-1.6	2.0	1.9	2.0	1.9	1.4	1.7	1.9
Forced expiratory volume in 1-second (FEV1)	0.1	0.4	1.5	-0.3	-0.5	0.7	0.0	0.5	0.6	1.2	-0.1	0.6
Pulse rate	0.0	0.1	0.3	-0.3	-0.2	0.2	-0.0	0.1	0.2	0.5	0.0	0.2
Happiness	0.3	0.4	1.1	-1.1	-0.0	0.6	0.7	0.6	0.5	0.1	0.9	0.6
Noisy workplace	0.1	0.1	0.6	-0.0	-0.8	0.1	-0.2	0.0	0.1	0.3	-0.2	0.1
Qualifications: A levels/AS levels or equivalent	1.8	4.1	9.0	1.9	3.0	-1.5	-2.4	-1.8	-1.7	-0.9	-2.4	-1.7
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.6	1.8	0.6	0.0	-1.0	-0.5	-0.8	-0.9	-1.3	-0.5	-0.8
Mouth/teeth dental problems: Dentures	0.2	0.3	1.3	-0.3	-1.1	-0.4	-0.0	-0.3	-0.3	-0.7	0.2	-0.2
Asthma	0.2	0.3	0.5	-0.4	-0.7	0.7	0.6	0.7	0.6	0.2	0.4	0.7
Medication: Ibuprofen (e.g. Nurofen)	0.9	1.2	4.4	-0.9	-0.3	1.1	0.5	1.0	1.1	2.1	0.6	1.1
Medication: Cholesterol lowering	0.1	0.1	0.4	-0.5	0.1	-0.3	0.2	-0.1	-0.2	-0.6	0.6	-0.1
Depression (self-reported)	0.3	0.4	1.0	-1.0	-0.2	0.5	0.8	0.6	0.5	0.0	1.0	0.6
Medication: Lansoprazole	1.0	1.1	1.3	-0.9	-1.1	1.1	1.1	1.1	1.1	1.0	1.1	1.0
Prospective memory result	1.7	2.1	2.5	1.4	1.3	-1.6	-1.4	-1.5	-1.6	-1.5	-1.2	-1.6
Lung cancer (father)	0.7	0.8	2.8	0.9	1.7	-0.5	-1.0	-0.7	-0.5	0.4	-0.9	-0.7
Illnesses of mother	0.1	0.2	0.6	-0.5	-0.8	0.2	0.3	0.2	0.3	0.2	0.3	0.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.6	1.6	-0.6	-1.0	0.8	0.2	0.7	0.8	1.3	0.2	0.7
Pulse wave Arterial Stiffness index	0.8	1.0	1.6	1.0	0.6	-1.3	-0.9	-1.2	-1.1	-0.5	-0.7	-1.2
Impedance of arm (left)	4.2	19.2	23.9	-4.1	-3.5	4.9	4.1	4.7	4.8	4.7	3.7	4.7
Arm fat mass (right)	2.6	10.6	13.4	3.3	2.2	-3.6	-2.9	-3.5	-3.5	-3.7	-2.9	-3.4
Trunk predicted mass	11.4	64.9	72.2	8.1	7.6	-8.3	-8.3	-8.5	-8.4	-6.8	-7.9	-8.4
Standing height	5.7	56.5	67.4	7.5	7.8	-7.4	-8.2	-7.9	-7.6	-5.3	-7.8	-7.8
Length of working week for main job	0.5	0.6	1.1	0.6	0.4	-1.1	-0.5	-0.9	-0.9	-1.0	-0.3	-0.9
Exposure to tobacco smoke at home	0.1	0.1	0.2	-0.2	-0.2	-0.3	0.3	-0.2	-0.2	-0.2	0.5	-0.2
Breastfed as a baby	0.1	0.1	0.6	-0.1	-0.3	-0.0	-0.0	-0.0	0.1	0.8	0.0	0.1
Tense / ‘highly strung’	0.5	0.9	1.4	-1.1	1.1	1.2	0.8	1.0	1.0	0.5	0.8	0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	1.5	-0.6	-1.2	0.4	0.8	0.6	0.5	-0.1	0.8	0.5
Hair/balding pattern: Pattern 4	0.4	1.0	1.8	1.4	-0.4	-1.0	-0.9	-1.0	-0.9	-0.8	-1.3	-0.9
Birth weight of first child	0.1	0.2	0.5	0.5	0.6	-0.3	-0.7	-0.4	-0.4	0.0	-0.6	-0.5
Peak expiratory flow (PEF)	0.6	1.4	3.0	-1.1	-0.6	1.2	0.9	1.2	1.2	1.7	1.0	1.2
Pulse wave reflection index	0.5	0.7	0.9	1.0	0.6	-0.9	-0.9	-0.9	-0.9	-0.1	-0.7	-0.9
Ever highly irritable/argumentative for 2 days	0.1	0.2	0.4	-0.6	-0.2	0.2	0.5	0.3	0.3	0.0	0.6	0.3
Loud music exposure frequency	1.9	2.1	4.0	1.1	2.0	-1.7	-1.2	-1.6	-1.6	-1.1	-0.8	-1.6
Qualifications: O levels/GCSEs or equivalent	0.5	0.8	1.0	1.0	0.8	-0.9	-0.9	-0.9	-0.9	-0.7	-1.0	-0.8
Mouth/teeth dental problems: Bleeding gums	0.7	0.9	4.0	-1.0	-2.0	0.3	0.9	0.5	0.4	-0.7	1.0	0.6
Blood clot in the leg (DVT)	0.3	0.4	0.9	-0.5	-0.9	0.5	0.6	0.6	0.6	0.2	0.5	0.6
Medication: Paracetamol	2.8	4.7	5.4	-2.2	-1.9	2.3	2.2	2.3	2.3	1.7	2.1	2.3
Headache pain in last month	0.4	0.7	1.1	0.9	0.3	-1.0	-1.0	-1.0	-1.0	-0.4	-0.8	-1.0
Medication for cholesterol, blood pressure or diabetes	0.8	1.3	2.5	-0.6	-1.0	1.5	0.9	1.2	1.3	1.6	0.3	1.3
Glaucoma (self-reported)	2.1	2.5	3.3	1.5	1.7	-1.7	-1.4	-1.7	-1.7	-1.4	-1.1	-1.8
Gout (self-reported)	3.2	4.4	6.0	2.4	2.3	-2.0	-2.1	-2.1	-2.1	-1.1	-2.1	-2.2
Hypothyroidism/myxoedema (self-reported)	0.3	0.6	0.8	-0.4	-0.8	0.8	0.9	0.8	0.8	0.8	0.7	0.7
Medication: Amlodipine	5.2	7.3	9.9	1.9	2.8	-3.1	-2.4	-2.9	-3.0	-3.0	-1.6	-3.0
Medication: Ventolin 100micrograms inhaler	0.4	0.5	1.1	-0.8	-0.8	0.2	0.9	0.4	0.3	-0.7	1.1	0.4
Birth weight	0.0	0.0	0.2	0.0	0.4	-0.1	-0.1	-0.1	-0.1	-0.1	-0.1	-0.1
Chronic bronchitis/emphysema (mother)	1.4	1.6	2.6	-1.5	-1.1	1.1	1.4	1.3	1.2	0.9	1.6	1.2
High blood pressure (siblings)	2.0	2.9	3.8	1.9	0.5	-1.9	-1.7	-1.9	-1.9	-1.4	-1.7	-1.8
Forced vital capacity (FVC), Best measure	0.1	0.4	1.6	-0.3	-0.5	0.8	-0.1	0.6	0.7	1.3	-0.3	0.7
Body fat percentage	0.3	1.1	2.3	1.2	0.3	-1.3	-0.6	-1.1	-1.1	-1.5	-0.7	-1.1
Leg fat percentage (right)	0.1	0.5	1.9	0.6	-0.4	-0.9	0.0	-0.6	-0.7	-1.4	0.0	-0.6
Arm fat-free mass (right)	11.9	60.9	68.9	7.7	7.3	-8.3	-7.8	-8.3	-8.2	-6.9	-7.3	-8.2
Exposure to tobacco smoke outside home	2.6	3.5	5.9	-2.0	-2.4	1.4	2.1	1.7	1.6	1.3	2.3	1.7
Comparative body size at age 10	6.4	17.7	23.9	4.3	2.6	-4.4	-4.1	-4.4	-4.4	-4.9	-4.2	-4.2
Number of full brothers	4.7	5.9	7.3	-2.5	-2.7	2.2	2.7	2.4	2.4	1.8	2.6	2.5
Worry too long after embarrassment	0.0	0.1	0.2	0.2	0.4	0.1	-0.3	-0.1	-0.0	0.4	-0.3	-0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	1.7	2.2	3.0	-1.6	-1.3	1.4	1.7	1.5	1.5	1.0	1.7	1.5
Wheeze or whistling in the chest in last year	3.5	6.2	8.6	-2.6	-2.9	2.1	2.9	2.5	2.3	1.3	2.9	2.4
Number of children fathered	2.6	2.9	5.2	-1.9	-2.3	1.3	1.9	1.5	1.4	0.9	2.1	1.5
Reason for reducing amount of alcohol drunk: Health precaution	1.2	1.4	4.7	-0.5	-0.5	1.4	0.7	1.2	1.3	2.2	0.5	1.2
Age at first live birth	0.2	0.4	0.5	0.7	0.7	-0.7	-0.7	-0.7	-0.7	-0.5	-0.6	-0.7
Pulse wave peak to peak time	0.2	0.2	0.5	-0.4	0.1	0.7	0.2	0.5	0.6	0.2	0.1	0.5
Health satisfaction	0.1	0.2	0.4	-0.6	-0.1	0.2	0.5	0.3	0.2	-0.6	0.6	0.2
Shortness of breath walking on level ground	2.5	2.9	4.3	-1.9	-1.3	1.7	2.1	1.8	1.7	0.7	2.0	1.7
Qualifications: College or University degree	0.9	2.9	6.6	1.8	2.6	-1.3	-1.8	-1.6	-1.5	-0.6	-1.8	-1.6
Eye problems/disorders: None of the above	2.6	3.0	3.7	-1.6	-1.9	1.6	1.8	1.8	1.8	1.6	1.6	1.9
Mouth/teeth dental problems: Loose teeth	0.1	0.1	0.8	0.6	-0.9	-0.1	0.1	-0.0	-0.0	0.3	-0.1	-0.1
Emphysema/chronic bronchitis	0.2	0.2	1.0	-0.5	-0.5	-0.0	0.7	0.2	0.1	-0.2	1.0	0.1
Medication for pain relief, constipation, heartburn	2.1	3.5	5.5	2.3	1.7	-1.6	-2.0	-1.8	-1.7	-1.4	-2.3	-1.8
Neck or shoulder pain in last month	1.4	2.0	3.7	-1.7	-0.8	1.1	1.4	1.2	1.2	1.9	1.9	1.2
Medication: Blood pressure	2.6	4.7	6.2	1.7	2.2	-2.5	-2.0	-2.4	-2.4	-2.0	-1.4	-2.5
Angina (self-reported)	0.8	1.0	1.3	-0.9	-0.7	1.1	1.0	1.1	1.1	1.1	0.9	1.1
Migraine (self-reported)	0.1	0.1	0.2	-0.5	-0.4	0.1	0.3	0.1	0.1	0.1	0.5	0.1
Medication: Ibuprofen	0.4	0.5	1.3	-0.8	-0.5	0.7	0.4	0.6	0.7	1.1	0.5	0.7
Medication: Allopurinol	4.3	5.7	7.0	2.6	2.5	-2.3	-2.5	-2.4	-2.4	-1.7	-2.4	-2.5
Medication: Omeprazole	3.9	4.6	9.2	-2.9	-1.8	1.7	2.5	2.0	1.8	0.7	3.0	1.9
Medication: Seretide 50 evohaler	0.6	0.7	1.2	-1.1	-0.6	0.7	0.9	0.8	0.7	0.6	1.1	0.7
Mean time to correctly identify matches	0.3	0.6	1.0	0.7	0.9	-0.8	-0.7	-0.8	-0.8	-0.4	-0.4	-1.0
Heart disease (mother)	2.5	3.0	5.1	-1.5	-1.5	1.9	1.5	1.8	1.9	2.3	1.3	1.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.1	0.3	-0.2	0.6	-0.4	0.0	-0.2	-0.3	-0.2	0.3	-0.3
Whole body fat mass	2.8	11.7	14.1	3.5	2.7	-3.8	-3.1	-3.6	-3.7	-3.6	-3.0	-3.6
Leg fat mass (right)	2.4	9.5	12.6	3.1	2.0	-3.6	-2.6	-3.3	-3.4	-3.5	-2.5	-3.3
Arm predicted mass (right)	11.4	58.5	66.3	7.5	7.3	-8.1	-7.6	-8.1	-8.1	-6.7	-7.1	-8.1
Pulse rate, automated reading	0.3	0.9	1.5	-1.2	-0.4	0.9	1.0	0.9	0.9	0.9	1.2	0.9
Alcohol intake frequency.	5.6	13.0	19.4	2.8	3.1	-4.3	-3.0	-3.9	-4.1	-4.4	-2.1	-4.1
Comparative height size at age 10	10.0	55.3	63.7	7.5	7.6	-7.3	-8.0	-7.7	-7.5	-5.6	-7.6	-7.7
Number of full sisters	0.3	0.4	0.7	-0.8	-0.7	0.4	0.7	0.5	0.5	0.4	0.8	0.5
Suffer from ‘nerves’	1.1	1.7	2.5	0.6	1.5	-1.5	-1.1	-1.4	-1.5	-1.6	-0.5	-1.5
Overall health rating	0.5	1.0	3.5	0.1	0.2	-1.3	-0.5	-1.0	-1.2	-1.9	-0.0	-1.0
Chest pain or discomfort	8.7	12.5	16.9	-3.9	-3.8	3.1	3.9	3.5	3.3	2.6	4.1	3.5
Had major operations	5.3	6.3	7.8	2.1	2.8	-2.5	-2.4	-2.5	-2.6	-2.8	-2.1	-2.5
Age at last live birth	0.2	0.3	0.7	0.5	0.8	-0.4	-0.5	-0.4	-0.4	-0.3	-0.6	-0.4
Family relationship satisfaction	0.6	0.7	1.0	-0.9	-0.6	0.9	1.0	0.9	0.8	-0.0	0.9	0.9
Leg pain on walking	0.1	0.1	0.6	0.0	0.8	0.1	0.1	0.1	0.0	-0.5	0.0	-0.0
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.2	0.9	-0.8	-0.1	-0.0	0.7	0.2	0.1	-0.3	0.9	0.2
Commuting to job workplace: Car/motor vehicle	0.0	0.0	0.2	0.3	0.4	-0.0	-0.2	-0.1	-0.1	0.1	-0.2	-0.1
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	0.6	0.8	0.8	-0.6	-0.8	-0.7	-0.6	-0.1	-0.7	-0.7
Medication: Aspirin	0.2	0.2	0.5	0.1	-0.3	-0.7	-0.1	-0.5	-0.6	-0.7	0.2	-0.5
Supplements: Vitamin C	0.1	0.1	0.3	-0.1	0.3	0.2	0.1	0.2	0.2	0.5	0.2	0.1
Knee pain experienced in last month	2.1	3.3	4.7	1.6	1.3	-2.2	-1.6	-2.0	-2.0	-2.0	-1.3	-2.0
Hypertension (Self-reported)	1.0	2.7	4.7	0.9	1.2	-2.2	-1.4	-1.9	-2.0	-1.9	-0.7	-1.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	3.4	4.0	5.6	-1.8	-2.4	2.1	1.8	2.0	2.1	2.1	1.6	2.0
Illnesses of father: Heart disease	0.2	0.2	1.3	0.2	-1.1	-0.3	0.0	-0.2	-0.2	-0.7	-0.1	-0.2
Illnesses of siblings: Diabetes	1.9	2.4	4.1	1.6	2.0	-1.5	-1.4	-1.5	-1.5	-1.0	-1.3	-1.6
Smoking status: Previous	1.4	2.1	2.6	-1.1	-1.3	1.6	1.3	1.5	1.6	1.6	1.1	1.6
Forced expiratory volume in 1-second (FEV1), predicted	0.8	1.6	3.3	0.9	1.8	-1.3	-1.4	-1.4	-1.3	-0.2	-1.0	-1.3
Whole body fat-free mass	11.2	63.9	71.2	8.0	7.4	-8.3	-8.1	-8.4	-8.3	-7.0	-7.8	-8.4
Leg fat-free mass (right)	9.5	50.9	56.4	7.1	6.4	-7.4	-7.2	-7.5	-7.5	-6.5	-7.0	-7.4
Arm fat percentage (left)	0.3	1.1	3.2	1.1	-0.1	-1.3	-0.5	-1.1	-1.2	-1.8	-0.6	-1.0
Average weekly red wine intake	2.4	3.6	6.6	-1.3	-1.8	2.2	1.5	2.0	2.1	2.6	1.0	2.0
Handedness (chirality/laterality): Left-handed	0.3	0.4	0.6	0.8	-0.5	-0.7	-0.5	-0.7	-0.7	-0.6	-0.4	-0.8
Mood swings	0.2	0.5	1.6	-0.1	-0.3	-0.8	-0.3	-0.7	-0.8	-1.3	0.1	-0.7
Loneliness, isolation	0.4	0.6	0.8	0.6	0.5	-0.9	-0.8	-0.9	-0.9	-0.9	-0.7	-0.8
Long-standing illness, disability or infirmity	0.2	0.3	0.9	-0.8	-0.4	-0.3	0.6	0.0	-0.1	-0.9	0.9	0.0
Ever had bowel cancer screening	4.0	4.7	5.3	-2.0	-2.2	2.3	2.1	2.3	2.3	2.1	1.9	2.3
Diabetes diagnosed by doctor	3.1	5.0	8.0	1.6	1.3	-2.8	-1.9	-2.5	-2.6	-2.8	-1.4	-2.5
Ever had stillbirth, spontaneous miscarriage or termination	0.9	1.0	1.7	-1.3	-0.7	0.9	0.9	0.9	0.9	1.1	1.1	0.9
Friendships satisfaction	0.3	0.4	1.3	-0.8	-0.4	0.2	0.8	0.4	0.3	-0.1	1.1	0.3
Qualifications: nursing, teaching	0.9	1.4	2.5	1.3	1.6	-1.0	-1.3	-1.1	-1.1	-0.8	-1.3	-1.2
Commuting to job workplace: Walk	0.4	0.4	1.1	-0.8	-0.6	0.2	0.9	0.4	0.3	0.1	1.1	0.4
Eye problems/disorders: Cataract	0.3	0.3	0.8	0.3	0.9	-0.4	-0.6	-0.5	-0.5	-0.6	-0.5	-0.5
Mouth/teeth dental problems: Mouth ulcers	0.6	1.0	2.0	0.6	0.5	-1.2	-0.8	-1.1	-1.1	-1.4	-0.4	-1.2
Medication for cholesterol	0.1	0.1	0.2	-0.1	-0.4	0.4	0.2	0.4	0.4	0.2	0.1	0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	3.3	3.9	7.0	-2.0	-2.6	1.5	2.2	1.8	1.7	1.5	2.3	1.8
Back pain experienced in last month	0.3	0.5	0.7	0.6	0.3	-0.8	-0.6	-0.8	-0.8	-0.8	-0.4	-0.8
Mineral and other dietary supplements	1.6	2.1	3.3	-1.8	-1.6	1.1	1.8	1.4	1.3	0.3	1.8	1.4
Breast cancer (self-reported)	0.1	0.1	0.3	0.0	0.5	0.5	0.3	0.4	0.4	-0.1	0.0	0.4
Asthma (self-reported)	0.0	0.1	0.1	-0.1	-0.2	0.4	0.3	0.4	0.3	-0.1	0.1	0.3
Osteoporosis (self-reported)	0.2	0.3	0.5	-0.2	-0.3	0.7	0.5	0.6	0.7	0.7	0.3	0.6
Osteoarthritis (self-reported)	4.3	5.6	7.2	2.5	2.5	-2.1	-2.6	-2.3	-2.2	-2.1	-2.7	-2.3
Medication: Aspirin	0.1	0.2	0.5	0.0	-0.3	-0.6	-0.1	-0.4	-0.5	-0.7	0.2	-0.5
Medication: Gliclazide	0.3	0.3	1.9	0.1	-0.7	-0.5	-0.0	-0.3	-0.5	-1.4	0.0	-0.3
Illnesses of father: None of the above (group 1)	0.2	0.2	0.5	0.5	0.7	-0.3	-0.5	-0.4	-0.3	0.6	-0.5	-0.4
Smoking status: Current	0.1	0.1	0.2	-0.2	-0.5	0.2	0.4	0.2	0.2	-0.4	0.2	0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.0	4.2	6.6	-1.5	-1.8	2.6	1.5	2.2	2.4	2.5	1.0	2.3
Whole body water mass	11.0	62.8	69.9	8.0	7.3	-8.2	-8.1	-8.4	-8.3	-7.0	-7.7	-8.3
Leg predicted mass (right)	9.6	51.4	57.0	7.2	6.4	-7.5	-7.3	-7.5	-7.5	-6.6	-7.0	-7.5
Arm fat mass (left)	2.8	11.6	15.0	3.4	2.3	-3.9	-3.0	-3.6	-3.7	-3.9	-2.9	-3.6
Number of self-reported non-cancer illnesses	0.4	0.8	1.2	-0.9	-1.1	0.7	0.9	0.8	0.8	0.6	0.9	0.9
Average weekly champagne plus white wine intake	0.1	0.1	0.3	0.3	0.3	0.3	-0.3	0.1	0.2	0.6	-0.5	0.1
Miserableness	0.3	0.5	1.7	-1.1	-0.9	-0.1	0.8	0.2	0.1	-0.5	1.3	0.2
Guilty feelings	0.9	1.3	2.0	-1.3	-0.9	1.0	1.2	1.1	1.1	0.9	1.4	1.0
Wears glasses or contact lenses	1.1	1.3	2.7	0.6	1.6	-1.1	-0.7	-1.0	-1.2	-1.6	-0.4	-1.2
Ever taken oral contraceptive pill	0.7	0.8	1.6	-1.3	-0.9	0.6	0.8	0.7	0.7	1.1	1.2	0.8
Hearing aid user	0.2	0.2	1.2	-0.5	-1.1	0.2	0.3	0.2	0.3	0.4	0.4	0.3
Mother’s age at death	0.0	0.0	0.1	0.3	0.2	-0.2	0.0	-0.1	-0.2	-0.3	-0.1	-0.2
Financial situation satisfaction	1.1	1.3	3.2	-1.8	-1.0	0.8	1.3	1.0	0.9	-0.1	1.6	1.0
Tinnitus: Yes, now most or all of the time	0.2	0.3	1.1	-0.7	-1.0	0.1	0.5	0.3	0.2	-0.1	0.6	0.3
Commuting to job workplace: Public transport	2.1	2.5	4.6	1.5	2.1	-1.6	-1.5	-1.6	-1.6	-1.1	-1.3	-1.7
Eye problems/disorders: Glaucoma	5.0	5.9	7.1	2.4	2.2	-2.5	-2.4	-2.6	-2.6	-2.1	-2.2	-2.7
Medication: Blood pressure	0.6	1.2	1.9	0.8	0.8	-1.4	-0.9	-1.2	-1.3	-1.2	-0.6	-1.2
Pain type(s) experienced in last month: Hip pain	0.1	0.1	0.3	-0.1	0.1	-0.5	-0.1	-0.3	-0.4	-0.5	0.1	-0.3
Supplements: Fish oil (including cod liver oil)	3.4	4.4	7.5	2.7	1.9	-1.7	-2.4	-2.0	-1.9	-1.1	-2.7	-2.0
High cholesterol (Self-reported)	1.9	3.4	8.0	-2.2	-2.8	1.1	2.1	1.5	1.3	0.1	2.4	1.5
Medication: Bendroflumethiazide	0.1	0.2	0.5	-0.2	0.2	-0.6	0.2	-0.4	-0.4	-0.7	0.5	-0.4
Medication: Paracetamol	1.4	2.2	3.0	-1.7	-1.5	1.5	1.6	1.5	1.5	0.7	1.5	1.6
Medication: Lisinopril	2.3	3.0	3.9	1.7	1.5	-1.9	-1.6	-1.9	-1.9	-1.6	-1.4	-2.0
Medication: Atorvastatin	0.1	0.1	0.2	-0.4	0.2	-0.3	0.1	-0.1	-0.2	0.1	0.5	-0.1
Illnesses of father: High blood pressure	0.3	0.4	1.3	0.4	0.2	-0.7	-0.4	-0.6	-0.6	-1.1	-0.4	-0.5
Alcohol drinker status: Never	0.3	0.3	0.5	0.5	0.7	-0.6	-0.5	-0.6	-0.6	-0.5	-0.3	-0.7
Ever smoked	2.4	4.2	4.9	-2.2	-2.1	2.1	2.2	2.2	2.1	1.2	2.1	2.2
Basal metabolic rate	10.4	57.5	64.3	7.6	6.9	-7.9	-7.6	-8.0	-8.0	-6.8	-7.3	-8.0
Leg fat percentage (left)	0.3	1.0	3.3	0.8	-0.1	-1.3	-0.3	-1.0	-1.1	-1.8	-0.2	-1.0
Arm fat-free mass (left)	10.7	54.4	61.0	7.4	6.7	-7.8	-7.4	-7.8	-7.8	-6.7	-7.0	-7.8
Number of operations (self-reported)	0.0	0.0	0.1	0.2	0.2	-0.2	-0.1	-0.2	-0.2	0.1	-0.1	-0.2
Average weekly beer plus cider intake	1.5	2.1	2.8	-1.7	-1.7	1.3	1.6	1.5	1.4	0.8	1.5	1.5
Irritability	0.1	0.1	0.3	-0.2	0.1	-0.4	-0.2	-0.3	-0.3	-0.6	0.1	-0.2
Risk taking	2.7	3.9	6.6	-1.9	-2.6	1.9	2.0	1.9	2.0	1.7	1.7	2.1
Ever had prostate specific antigen (PSA) test	0.3	0.4	1.0	0.9	0.2	-0.4	-0.8	-0.5	-0.5	-0.3	-1.0	-0.5
Fractured/broken bones in last 5 years	0.5	0.7	0.9	-0.9	-0.8	0.7	0.9	0.8	0.8	0.4	0.9	0.9
Age started oral contraceptive pill	0.1	0.1	0.6	0.3	-0.5	-0.0	0.0	-0.0	-0.1	-0.8	-0.2	-0.1
Diastolic blood pressure, automated reading	0.9	2.9	3.7	1.8	0.9	-1.9	-1.9	-1.9	-1.8	-1.0	-1.8	-1.9
Ever depressed for a whole week	0.1	0.1	0.3	0.2	-0.5	0.2	-0.1	0.1	0.1	-0.6	-0.4	0.1
Unable to work because of sickness or disability	0.2	0.2	0.7	-0.0	0.1	-0.5	-0.4	-0.5	-0.5	-0.8	-0.2	-0.5
Commuting to job workplace: Cycle	0.4	0.5	1.1	-0.9	-1.1	0.4	0.6	0.5	0.6	0.7	0.8	0.7
Myopia	1.1	1.6	2.0	-1.4	-1.1	1.3	1.3	1.4	1.3	0.7	1.2	1.4
Vascular/heart problems diagnosed by doctor	0.3	0.8	1.7	-0.3	-0.6	1.3	0.6	1.0	1.1	1.1	-0.0	1.1
Cholesterol lowering medication	0.7	1.0	2.9	-0.9	-1.7	0.7	1.3	0.9	0.8	0.1	1.1	0.9
Medication: Omeprazole (e.g. Zanprol)	3.4	4.2	8.8	-2.9	-1.9	1.4	2.4	1.8	1.6	0.3	3.0	1.8
Pain experienced in last month	0.1	0.2	0.5	-0.1	0.6	0.7	0.3	0.5	0.6	0.5	-0.1	0.6
Supplements: Calcium	1.1	1.3	1.8	-0.8	-1.3	1.2	1.1	1.2	1.2	1.0	0.9	1.2
Basal cell carcinoma (self-reported)	1.5	1.8	3.4	1.3	1.9	-0.9	-1.6	-1.2	-1.1	-1.0	-1.7	-1.1
Heart attack/myocardial infarction (self-reported)	0.1	0.2	0.5	0.4	0.2	-0.5	-0.3	-0.4	-0.4	-0.7	-0.3	-0.4
Deep venous thrombosis (DVT) (self-reported)	0.3	0.3	0.4	-0.6	-0.7	0.5	0.6	0.6	0.6	0.3	0.6	0.6
Heart disease (siblings)	2.4	2.9	5.2	-1.5	-2.3	1.7	1.7	1.7	1.7	1.4	1.4	1.8
Alcohol drinker status: Previous	0.8	0.9	2.1	0.2	0.9	-1.1	-0.6	-1.0	-1.1	-1.5	-0.1	-1.0
Pack years of smoking	0.1	0.1	0.4	-0.2	0.6	0.4	0.3	0.3	0.3	0.1	0.1	0.3
Impedance of whole body	4.2	21.5	25.4	-4.5	-3.7	5.0	4.4	4.9	5.0	4.9	4.2	4.9
Leg fat mass (left)	2.8	11.0	14.7	3.3	2.3	-3.8	-2.9	-3.6	-3.7	-3.7	-2.7	-3.6
Arm predicted mass (left)	9.9	50.4	56.9	7.0	6.4	-7.5	-7.1	-7.5	-7.5	-6.5	-6.7	-7.5