[Hub]/) : Traits : Lung FVC : ← →

chr17:36,710,513-38,783,469

Best TWAS P=8.68e-17 · Best GWAS P=8.68e-17 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	TCAP	0.06	0.00	blup	332	0.01	8.3e-03	-8.0	-5.1	3.0e-07	0.81	0.05	0.90	FALSE
2	GTEx	Adipose Visceral Omentum	PGAP3	0.12	0.11	lasso	6	0.10	7.1e-06	-6.8	-6.7	2.4e-11	0.68	0.87	0.11	FALSE
3	GTEx	Adrenal Gland	PGAP3	0.17	0.14	lasso	2	0.12	3.2e-05	-6.7	-6.8	1.1e-11	0.76	0.52	0.17	FALSE
4	GTEx	Artery Aorta	PGAP3	0.13	0.04	lasso	3	0.10	5.3e-06	-6.7	-6.8	8.3e-12	0.68	0.14	0.82	FALSE
5	GTEx	Artery Coronary	PGAP3	0.16	0.10	lasso	4	0.06	5.9e-03	-6.2	-6.7	2.1e-11	0.69	0.12	0.48	FALSE
6	GTEx	Breast Mammary Tissue	PGAP3	0.10	0.07	lasso	4	0.07	1.5e-04	-6.5	-6.7	2.6e-11	0.56	0.27	0.11	FALSE
7	GTEx	Colon Transverse	PGAP3	0.24	0.20	enet	19	0.20	8.3e-10	-6.7	-5.6	2.0e-08	0.70	0.82	0.18	FALSE
8	GTEx	Esophagus Muscularis	FBXL20	0.04	0.03	lasso	3	0.02	1.2e-02	-6.4	7.2	5.0e-13	-0.88	0.08	0.78	FALSE
9	GTEx	Esophagus Muscularis	PGAP3	0.11	0.08	enet	10	0.10	1.1e-06	-6.7	-6.8	7.7e-12	0.70	0.90	0.07	FALSE
10	GTEx	Heart Atrial Appendage	PPP1R1B	0.09	0.04	enet	10	0.08	2.2e-04	-3.7	-5.6	1.8e-08	0.42	0.49	0.13	FALSE
11	GTEx	Heart Atrial Appendage	ERBB2	0.13	0.04	enet	18	0.02	4.8e-02	-6.5	-5.6	2.5e-08	0.47	0.21	0.28	FALSE
12	GTEx	Heart Atrial Appendage	PGAP3	0.13	0.16	lasso	3	0.18	2.6e-08	-6.3	-6.5	8.7e-11	0.66	0.98	0.01	FALSE
13	GTEx	Heart Left Ventricle	PNMT	0.06	0.03	lasso	1	0.03	1.3e-02	-8.3	-8.3	8.7e-17	1.00	0.04	0.90	TRUE
14	GTEx	Heart Left Ventricle	PGAP3	0.17	0.14	lasso	5	0.12	4.3e-07	-6.7	-7.2	6.2e-13	0.79	0.60	0.39	FALSE
15	GTEx	Liver	PGAP3	0.27	0.17	lasso	4	0.13	1.7e-04	-6.4	-6.7	1.6e-11	0.59	0.53	0.27	FALSE
16	GTEx	Lung	PGAP3	0.24	0.14	lasso	7	0.12	2.3e-09	-6.7	-6.4	1.9e-10	0.67	0.99	0.01	FALSE
17	GTEx	Muscle Skeletal	PGAP3	0.04	0.03	lasso	5	0.04	1.3e-04	-6.8	-6.4	1.9e-10	0.59	0.42	0.37	FALSE
18	GTEx	Nerve Tibial	ERBB2	0.08	0.08	lasso	5	0.07	1.3e-05	-6.3	-6.8	9.3e-12	0.73	0.80	0.18	FALSE
19	GTEx	Nerve Tibial	PGAP3	0.19	0.11	lasso	5	0.12	1.1e-08	-6.7	-6.7	1.7e-11	0.72	0.99	0.01	FALSE
20	GTEx	Pancreas	PGAP3	0.37	0.25	lasso	6	0.21	1.9e-09	-6.4	-5.7	9.8e-09	0.64	0.97	0.03	FALSE
21	GTEx	Pituitary	PGAP3	0.15	0.22	lasso	2	0.19	1.8e-05	-6.5	-6.5	8.5e-11	0.64	0.32	0.10	FALSE
22	GTEx	Prostate	PGAP3	0.23	0.03	enet	26	0.06	1.6e-02	-6.7	-6.6	3.3e-11	0.72	0.13	0.46	FALSE
23	GTEx	Skin Not Sun Exposed Suprapubic	PGAP3	0.22	0.09	enet	33	0.14	3.4e-08	-6.7	-5.2	1.6e-07	0.62	0.99	0.01	FALSE
24	GTEx	Skin Not Sun Exposed Suprapubic	TCAP	0.07	0.02	enet	7	0.01	1.2e-01	-6.2	-6.4	1.2e-10	0.66	0.14	0.16	FALSE
25	GTEx	Skin Sun Exposed Lower leg	ERBB2	0.10	0.01	enet	8	0.01	3.5e-02	-6.2	-5.2	1.6e-07	0.63	0.36	0.11	FALSE
26	GTEx	Skin Sun Exposed Lower leg	PGAP3	0.14	0.10	lasso	6	0.07	1.1e-06	-6.4	-6.8	1.1e-11	0.74	1.00	0.00	FALSE
27	GTEx	Skin Sun Exposed Lower leg	ORMDL3	0.04	0.02	lasso	5	0.01	1.1e-01	-6.7	-5.7	1.4e-08	0.74	0.14	0.13	FALSE
28	GTEx	Small Intestine Terminal Ileum	FBXL20	0.32	0.32	lasso	5	0.27	1.1e-06	-6.9	7.1	1.5e-12	-0.92	0.08	0.88	FALSE
29	GTEx	Small Intestine Terminal Ileum	RP11-690G19.3	0.21	0.24	lasso	2	0.24	5.3e-06	-6.9	6.7	1.5e-11	-0.90	0.06	0.87	FALSE
30	GTEx	Stomach	PGAP3	0.41	0.18	enet	16	0.25	2.3e-12	-6.7	-5.9	3.9e-09	0.53	0.99	0.01	FALSE
31	GTEx	Thyroid	PGAP3	0.19	0.21	lasso	10	0.24	3.5e-18	-5.8	-6.2	7.4e-10	0.62	1.00	0.00	FALSE
32	GTEx	Thyroid	RP11-690G19.3	0.04	0.03	enet	6	0.02	1.5e-02	-5.0	6.5	7.0e-11	-0.70	0.10	0.69	FALSE
33	METSIM	Adipose	PGAP3	0.06	0.05	lasso	4	0.05	8.8e-08	-6.4	-6.8	7.2e-12	0.74	0.99	0.01	FALSE
34	YFS	Blood	FBXL20	0.05	0.10	lasso	15	0.10	6.5e-30	-8.1	-8.1	4.5e-16	0.97	0.05	0.95	FALSE
35	YFS	Blood	PGAP3	0.08	0.12	lasso	11	0.12	1.7e-35	-6.8	-6.9	5.6e-12	0.68	1.00	0.00	FALSE
36	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	PGAP3	0.07	0.12	blup	37	0.11	1.2e-09	-6.7	-6.8	9.7e-12	0.70	0.01	0.99	FALSE
37	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	PGAP3	0.04	0.01	blup	41	0.01	1.2e-01	-6.7	-7.0	3.7e-12	0.74	0.01	0.76	FALSE
38	The Cancer Genome Atlas	Colon Adenocarcinoma	PGAP3	0.10	0.17	blup	37	0.17	6.4e-10	-6.4	-6.8	1.3e-11	0.68	0.03	0.97	FALSE
39	The Cancer Genome Atlas	Glioblastoma Multiforme	PGAP3	0.19	0.13	blup	37	0.16	1.5e-05	-6.4	-6.7	2.3e-11	0.71	0.02	0.96	FALSE
40	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	PGAP3	0.04	0.08	lasso	1	0.07	1.5e-08	-6.4	-6.4	1.6e-10	0.66	0.02	0.98	FALSE
41	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	STARD3	0.03	0.04	enet	5	0.02	8.2e-04	-6.8	-6.9	4.6e-12	0.77	0.01	0.98	FALSE
42	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	MED1	0.03	0.02	blup	29	0.02	1.0e-03	-8.0	-7.8	5.4e-15	0.98	0.01	0.98	FALSE
43	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PGAP3	0.12	0.12	lasso	4	0.13	5.3e-14	-6.4	-6.3	2.7e-10	0.62	0.04	0.96	FALSE
44	The Cancer Genome Atlas	Brain Lower Grade Glioma	PGAP3	0.05	0.08	lasso	10	0.08	2.1e-09	-6.4	-6.6	5.4e-11	0.67	0.02	0.98	FALSE
45	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	PGAP3	0.09	0.11	lasso	4	0.11	5.9e-06	-6.5	-6.6	3.5e-11	0.69	0.01	0.98	FALSE
46	The Cancer Genome Atlas	Lung Adenocarcinoma	PGAP3	0.06	0.06	lasso	4	0.06	4.5e-07	-5.8	-6.0	1.7e-09	0.62	0.07	0.93	FALSE
47	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	PGAP3	0.06	0.10	lasso	2	0.09	1.5e-10	-6.4	-6.4	1.5e-10	0.67	0.09	0.91	FALSE
48	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	STARD3	0.03	0.03	enet	8	0.04	6.6e-05	-6.2	-6.6	4.4e-11	0.70	0.09	0.86	FALSE
49	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	PGAP3	0.17	0.13	blup	41	0.10	6.8e-05	-5.8	-5.5	2.9e-08	0.55	0.04	0.92	FALSE
50	The Cancer Genome Atlas	Prostate Adenocarcinoma	PGAP3	0.18	0.26	enet	12	0.28	5.7e-30	-6.4	-6.4	1.4e-10	0.66	0.08	0.92	FALSE
51	The Cancer Genome Atlas	Prostate Adenocarcinoma	STARD3	0.05	0.04	blup	50	0.05	9.8e-06	-6.8	-5.9	4.6e-09	0.55	0.02	0.98	FALSE
52	The Cancer Genome Atlas	Rectum Adenocarcinoma	CDK12	0.17	0.00	blup	44	0.05	2.5e-02	-8.0	-8.2	2.8e-16	0.97	0.01	0.40	FALSE
53	The Cancer Genome Atlas	Rectum Adenocarcinoma	PGAP3	0.20	0.14	blup	38	0.16	1.4e-04	-6.5	-6.5	5.9e-11	0.72	0.01	0.79	FALSE
54	The Cancer Genome Atlas	Stomach Adenocarcinoma	PGAP3	0.05	0.05	lasso	4	0.05	1.0e-04	-6.2	-6.5	7.1e-11	0.68	0.03	0.93	FALSE
55	The Cancer Genome Atlas	Testicular Germ Cell Tumors	PGAP3	0.23	0.22	blup	38	0.24	3.6e-09	-6.7	-6.5	6.4e-11	0.74	0.01	0.98	FALSE
56	The Cancer Genome Atlas	Testicular Germ Cell Tumors	STARD3	0.05	0.06	lasso	2	0.04	1.7e-02	-6.7	-7.3	2.0e-13	0.74	0.01	0.78	FALSE
57	The Cancer Genome Atlas	Thyroid Carcinoma	PGAP3	0.10	0.16	lasso	5	0.17	1.4e-16	-6.4	-6.8	1.4e-11	0.72	0.02	0.98	FALSE
58	The Cancer Genome Atlas	Thyroid Carcinoma	PNMT	0.03	0.05	lasso	4	0.04	6.2e-05	-5.0	-5.4	5.5e-08	0.58	0.03	0.95	FALSE
59	The Cancer Genome Atlas	Thyroid Carcinoma	STARD3	0.10	0.06	lasso	5	0.05	2.6e-05	-6.2	-6.0	1.5e-09	0.61	0.08	0.91	FALSE