TWAS hub - TCAP

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.059	0.026	0.00029	-0.001	0.013	-0.002	0.009	0.001	0.400	0.0083	0.64	0.023	0.26
2	GTEx	Artery Coronary	0.273	0.155	0.00760	-0.009	NA	-0.004	NA	-0.009	0.940	NA	0.46	NA	0.98
3	GTEx	Skin Not Sun Exposed Suprapubic	0.071	0.039	0.00620	0.021	NA	0.007	NA	0.004	0.024	NA	0.12	NA	0.18

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	3
Respiratory disease	25.1	55.8	141.6	5.1	11.9
Asthma (self-reported)	22.3	44.5	108.2	5.0	10.4
Asthma	21.7	42.8	106.1	4.7	10.3
HDL Cholesterol	13.7	22.9	46.1	-4.8	-6.8
Blood White Count	12.6	93.5	278.9	-1.3	16.7
Allergy	9.7	22.3	59.9	-2.6	-7.7
Primary Biliary Cirrhosis	8.9	12.7	21.2	-4.6	-4.1
Medication: Ventolin 100micrograms inhaler	8.7	11.2	24.7	3.0	5.0
Irritable Bowel Disease (IBD)	7.6	18.0	51.4	-1.6	-7.2
Blood Red Count	7.4	71.8	125.4	11.2	9.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	7.4	15.7	34.5	-3.5	-5.9
Rheumatoid Arthritis	6.6	9.1	17.3	-3.2	-4.2
Crohns Disease (2017)	6.4	14.0	39.7	-1.6	-6.3
Loud music exposure frequency	5.7	6.2	11.9	-3.5	-2.6
Wears glasses or contact lenses	5.3	6.1	9.4	-3.1	-3.0
Falls in the last year	4.9	6.6	18.9	-4.3	-1.0
Ulcerative Colitis	4.6	6.6	16.2	-1.9	-4.0
Mouth/teeth dental problems: Dentures	4.6	7.8	14.1	3.0	3.8
Lung FVC	4.4	22.6	41.5	-5.1	-6.4
Hayfever, allergic rhinitis or eczema	4.4	9.6	25.2	1.9	5.0
Type 2 Diabetes (T2D) (2018)	4.3	8.1	13.6	3.3	3.7
Commuting to job workplace: Public transport	4.3	5.1	8.3	-2.9	-2.6
Wheeze or whistling in the chest in last year	4.1	7.3	20.8	1.0	4.6
Alcohol intake frequency.	3.9	9.0	16.4	4.0	3.2
Ever smoked	3.9	6.8	13.6	2.6	3.7
Allergy or Eczema	3.8	10.1	27.1	1.8	5.2
Past tobacco smoking	3.8	7.0	14.8	-2.5	-3.9
Crohns Disease (2012)	3.7	6.0	16.4	-1.3	-4.0
Smoking Status	3.7	9.0	20.7	2.5	4.5
Ulcerative Colitis (UC)	3.6	6.7	19.4	-0.9	-4.4
Lupus	3.6	5.5	10.4	-2.5	-3.2
Prostate Cancer	3.5	4.9	13.0	3.6	1.3
Hayfever/allergic rhinitis (self-reported)	3.4	4.6	6.9	2.6	2.6
Qualifications: College or University degree	3.4	10.8	28.6	-5.4	-2.0
Pulse wave Arterial Stiffness index	3.3	3.9	9.9	3.1	1.3
Ever depressed for a whole week	3.2	4.0	6.3	2.4	2.5
Pulse wave peak to peak time	3.1	3.7	9.4	-3.1	-1.3
Ovarian Cancer	3.0	4.0	11.2	3.3	0.9
Reason for reducing amount of alcohol drunk: Health precaution	3.0	3.5	6.3	-2.5	-2.1
Medication: Seretide 50 evohaler	3.0	3.5	6.9	2.6	1.9
Number of live births	2.8	4.0	9.7	3.1	1.5
Suffer from ‘nerves’	2.8	4.4	8.9	-2.1	-3.0
Bipolar Disorder or Schizophrenia	2.6	6.3	10.6	2.9	3.2
Type 2 Diabetes (T2D) (2012)	2.5	2.9	5.2	2.3	1.9
Knee pain experienced in last month	2.5	3.8	7.9	-2.8	-1.9
Blood Platelet Count	2.4	28.2	58.5	-7.7	-5.1
Number of full brothers	2.3	2.9	4.5	2.1	2.1
Smoking status: Previous	2.3	3.5	7.5	1.7	2.7
Schizophrenia (2018)	2.2	4.6	8.9	3.0	2.2
Pulse rate	2.2	3.7	11.0	-0.1	3.3
Exposure to tobacco smoke outside home	2.2	3.0	6.8	-2.6	-1.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.2	2.6	4.3	2.1	1.9
Mother’s age at death	2.2	2.7	7.1	-2.7	-1.1
Risk taking	2.2	3.2	5.2	-2.3	-2.1
Tinnitus: Yes, but not now, but have in the past	2.0	2.1	4.3	-1.5	-2.1
Number of incorrect matches in round	2.0	3.3	5.5	2.3	2.1
Diabetes (self-reported)	2.0	3.1	6.8	1.6	2.6
Time employed in main current job	2.0	2.3	4.7	-2.2	-1.5
Father’s age at death	2.0	2.7	4.8	-2.2	-1.9
Eye problems/disorders: None of the above	2.0	2.3	5.2	1.4	2.3
Mineral and other dietary supplements	2.0	2.7	7.3	2.7	0.9
Average weekly champagne plus white wine intake	2.0	2.8	7.1	-2.7	-1.1
Alcohol drinker status: Previous	2.0	2.2	4.4	1.5	2.1
Worry (Nagel 2018)	1.8	3.8	6.0	-2.3	-2.5
Pulse rate, automated reading	1.8	5.7	16.9	0.6	4.1
Depression (Nagel 2018)	1.7	2.5	6.2	-2.5	-1.2
Alzheimer’s Disease (in father)	1.7	1.9	5.1	2.3	-0.7
Mean Putamen Volume	1.7	1.9	4.6	1.1	2.1
Schizophrenia (2014)	1.7	3.8	6.2	2.5	2.3
Current tobacco smoking	1.7	2.7	4.8	1.8	2.2
Birth weight	1.7	3.7	10.0	3.2	1.1
Diabetes diagnosed by doctor	1.7	2.8	5.1	1.8	2.2
Supplements: Fish oil (including cod liver oil)	1.7	2.2	6.4	-2.5	0.4
Myopia	1.7	2.5	4.2	2.0	1.8
Age at First Birth	1.6	2.3	4.2	-1.6	-2.1
Nervous feelings	1.6	3.0	5.4	-1.9	-2.3
Forced expiratory volume in 1-second (FEV1), Best measure	1.6	5.2	12.5	-1.8	-3.5
Number of self-reported non-cancer illnesses	1.6	2.8	8.1	0.6	2.8
Ever used hormone-replacement therapy (HRT)	1.5	1.9	5.7	-0.3	2.4
Forced expiratory volume in 1-second (FEV1)	1.5	5.0	13.3	-1.3	-3.6
Chest pain or discomfort	1.5	2.2	6.4	-0.4	2.5
Commuting to job workplace: Car/motor vehicle	1.5	1.7	4.4	2.1	0.8
Osteoporosis (self-reported)	1.5	1.9	3.6	-1.9	-1.4
Bipolar Disorder (2018)	1.4	2.2	5.8	0.9	2.4
Average weekly spirits intake	1.4	1.8	3.9	-2.0	-1.2
Forced vital capacity (FVC)	1.4	5.5	12.5	-2.0	-3.5
Mood swings	1.4	2.5	4.8	-1.7	-2.2
Medication: Gliclazide	1.4	1.6	4.3	2.1	0.7
Smoking status: Current	1.4	2.3	4.5	1.5	2.1
Waist Hip Ratio (WHR)	1.3	5.8	14.0	-3.7	-1.9
Townsend deprivation index at recruitment	1.3	1.8	5.4	0.0	2.3
Taking other prescription medications	1.3	2.1	5.6	0.8	2.4
Illnesses of father: Heart disease	1.3	1.9	4.1	1.2	2.0
Average weekly red wine intake	1.3	1.9	4.1	-1.3	-2.0
Long-standing illness, disability or infirmity	1.3	1.9	5.6	0.5	2.4
Medication: Metformin	1.2	1.7	3.5	1.3	1.9
Frequency of tenseness / restlessness in last 2 weeks	1.2	1.9	5.0	-2.2	-0.8
Forced vital capacity (FVC), Best measure	1.2	4.3	8.5	-2.1	-2.9
Number of children fathered	1.2	1.3	2.7	1.6	1.1
Medication: Omeprazole	1.2	1.5	4.3	-2.1	0.2
Had major operations	1.2	1.4	3.4	1.8	0.8
Medication: Lisinopril	1.2	1.5	2.9	-1.3	-1.7
Sensitivity / hurt feelings	1.1	2.0	3.9	2.0	1.4
Ever unenthusiastic/disinterested for a whole week	1.1	1.4	2.7	1.6	1.2
Illnesses of siblings	1.1	1.5	3.3	-1.1	-1.8
Alcohol intake versus 10 years previously	1.1	1.6	3.6	1.9	-1.1
Noisy workplace	1.1	1.3	3.6	-1.9	0.5
Serious illness, injury or assault of a close relative in last 2 years	1.1	1.3	3.4	-1.8	-0.7
Birth weight of first child	1.1	1.9	3.6	1.5	1.9
Gout (self-reported)	1.1	1.5	4.0	-2.0	-0.7
Pain experienced in last month	1.1	1.8	4.6	2.1	0.9
Medication for hormone replacement therapy	1.0	1.1	2.8	-1.7	0.7
Medication: Co-codamol	1.0	1.2	2.6	-0.9	-1.6
Worrier / anxious feelings	1.0	1.8	5.1	-2.3	-0.6
Depression (self-reported)	1.0	1.2	3.5	-1.9	0.1
Exposure to tobacco smoke at home	1.0	1.1	2.3	-1.0	-1.5
Medication: Allopurinol	1.0	1.4	3.3	-1.8	0.9
Mouth/teeth dental problems: Mouth ulcers	1.0	1.6	4.6	-0.4	-2.1
Average weekly beer plus cider intake	1.0	1.5	4.3	-0.4	-2.1
Age started oral contraceptive pill	1.0	1.3	2.0	-1.4	-1.4
Heart disease (siblings)	1.0	1.3	3.8	0.3	1.9
Reaction Time	0.9	1.6	3.8	1.9	1.1
LDL Cholesterol	0.9	1.4	2.1	-1.5	-1.4
Severe depression (siblings)	0.9	1.0	3.0	0.1	1.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.9	1.2	3.1	-1.8	-0.7
Age when periods started (menarche)	0.9	2.2	4.9	-1.3	-2.2
Had menopause	0.9	1.1	2.7	-0.7	1.6
Mouth/teeth dental problems: Bleeding gums	0.9	1.2	2.4	-1.1	-1.5
Comparative body size at age 10	0.9	2.5	6.3	2.5	1.0
Neck or shoulder pain in last month	0.9	1.2	2.7	-1.6	1.0
Mean time to correctly identify matches	0.9	1.7	2.6	1.6	1.6
Age at last live birth	0.9	1.3	2.9	-1.0	-1.7
Supplements: Vitamin C	0.9	1.0	2.2	0.9	1.5
Osteoarthritis (self-reported)	0.9	1.1	3.0	-1.7	0.6
Cholesterol lowering medication	0.9	1.3	2.4	1.2	1.5
Basal cell carcinoma (self-reported)	0.9	1.0	2.8	-0.6	1.7
Triglycerides	0.8	1.3	3.8	-0.5	1.9
Frequency of depressed mood in last 2 weeks	0.8	1.2	3.5	-1.9	0.1
Qualifications: CSEs or equivalent	0.8	1.0	3.0	1.7	0.2
Financial difficulties in last 2 years	0.8	1.0	2.4	1.5	0.9
Medication: Ramipril	0.8	1.1	1.8	1.2	1.3
Mouth/teeth dental problems: Loose teeth	0.8	0.9	1.9	1.4	0.9
Emphysema/chronic bronchitis	0.8	0.9	2.0	0.9	1.4
Family relationship satisfaction	0.8	1.0	2.8	0.3	1.7
Handedness (chirality/laterality): Left-handed	0.8	0.9	1.7	1.0	1.3
Ever had bowel cancer screening	0.8	1.0	1.8	-1.3	-1.1
Friendships satisfaction	0.8	1.0	2.8	0.4	1.7
Financial situation satisfaction	0.8	1.0	2.8	1.7	-0.4
Medication: Bendroflumethiazide	0.8	1.2	2.4	1.1	1.5
Fractured/broken bones in last 5 years	0.8	1.1	2.8	-1.7	-0.6
Depressed Affect (Nagel 2018)	0.7	1.5	2.9	-1.7	-1.3
Vitamin and mineral supplements	0.7	1.0	2.4	1.6	-0.8
Qualifications: None of the above	0.7	1.6	4.0	0.9	2.0
Length of working week for main job	0.7	0.7	1.4	-1.2	0.9
Tense / ‘highly strung’	0.7	1.2	2.7	-1.0	-1.6
Medication: Paracetamol	0.7	1.2	3.5	-1.9	-0.3
Heart disease (mother)	0.7	0.9	1.6	-1.0	1.3
Number of operations (self-reported)	0.7	1.1	2.1	1.1	1.4
Supplements: Calcium	0.7	0.7	2.1	-1.4	-0.4
Heart attack/myocardial infarction (self-reported)	0.7	0.9	1.8	1.3	1.0
Fasting Glucose	0.6	0.7	1.8	0.6	1.4
Chronotype (morning person)	0.6	1.4	3.9	-0.5	-2.0
Hearing difficulty/problems: Yes	0.6	0.9	2.8	1.7	0.0
Eye problems/disorders: Diabetes related eye disease	0.6	0.7	1.5	-1.2	-0.8
Maternal smoking around birth	0.6	0.9	2.5	1.6	0.3
Chronic bronchitis/emphysema (father)	0.6	0.7	2.2	0.3	1.5
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.4	4.1	2.0	0.3
Neuroticism score	0.6	1.2	2.4	-1.6	-1.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.6	0.9	2.0	-1.4	-0.8
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.3	3.3	1.8	0.8
Medication: Omeprazole (e.g. Zanprol)	0.6	0.7	1.8	-1.3	0.7
Coronary Artery Disease (CAD)	0.5	0.6	1.6	1.3	0.4
Heart attack	0.5	0.7	1.2	1.1	0.9
Hip circumference	0.5	2.4	7.1	2.7	-0.1
Happiness	0.5	0.6	1.5	0.5	1.2
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.6	1.7	-0.4	-1.3
Hair/balding pattern: Pattern 4	0.5	1.2	3.4	-0.3	1.9
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.7	2.0	-1.4	0.1
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	1.7	0.2	1.3
Medication for cholesterol	0.5	0.8	2.1	0.6	-1.4
Illnesses of father: None of the above (group 1)	0.5	0.7	1.6	-0.6	-1.3
Medication: Blood pressure	0.5	1.0	1.7	1.1	1.3
Medication: Paracetamol	0.5	0.7	1.7	-1.3	-0.7
Illnesses of father: High blood pressure	0.5	0.6	1.4	0.6	-1.2
Leg fat percentage (left)	0.5	1.6	4.9	2.2	0.1
Ever had prostate specific antigen (PSA) test	0.5	0.6	1.4	1.2	0.6
Neuroticism (Nagel 2018)	0.4	1.0	1.6	-1.3	-1.2
Blood Eosinophil Count	0.4	3.3	6.0	-2.0	2.4
Heel T-Score	0.4	3.0	8.9	3.0	0.0
BMI	0.4	2.3	6.8	2.6	-0.2
Height	0.4	8.5	18.6	-2.6	-4.3
Neuroticism	0.4	1.0	1.8	-1.3	-1.1
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	1.3	-1.1	-0.6
Angina	0.4	0.5	1.0	-0.7	1.0
Trunk fat percentage	0.4	1.4	4.2	2.1	0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.4	0.9	2.8	1.7	0.1
Body mass index (BMI)	0.4	1.7	5.1	2.3	0.1
Medication: Lansoprazole	0.4	0.5	0.9	-0.8	-0.9
Illnesses of mother	0.4	0.5	1.4	1.2	-0.1
Ever highly irritable/argumentative for 2 days	0.4	0.4	1.0	1.0	0.5
Body fat percentage	0.4	1.5	4.3	2.1	0.3
Leg fat percentage (right)	0.4	1.5	4.5	2.1	0.3
Age at first live birth	0.4	0.8	1.5	-1.2	-0.9
Angina (self-reported)	0.4	0.6	0.9	-0.9	1.0
Medication: Ibuprofen	0.4	0.5	1.2	-0.4	-1.1
Whole body fat mass	0.4	1.5	4.6	2.1	0.0
Leg fat mass (right)	0.4	1.4	4.1	2.0	-0.3
Loneliness, isolation	0.4	0.5	1.0	-0.8	-1.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	1.4	0.3	1.2
Miserableness	0.4	0.6	1.5	-1.2	-0.6
Commuting to job workplace: Cycle	0.4	0.4	1.1	-1.0	-0.5
Leg fat mass (left)	0.4	1.6	4.7	2.2	-0.3
Relative age of first facial hair	0.3	0.5	1.5	-1.2	-0.2
Diabetes (father)	0.3	0.4	1.1	0.1	1.1
Diabetes (mother)	0.3	0.3	0.9	1.0	-0.3
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	0.5	0.7	0.7
Multivitamins +/- minerals	0.3	0.4	1.0	-0.5	1.0
Stomach or abdominal pain in last month	0.3	0.3	0.7	0.6	0.8
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	1.2	-0.1	1.1
Medication: Atenolol	0.3	0.4	0.6	0.7	0.8
Trunk fat mass	0.3	1.3	4.0	2.0	-0.1
Mouth/teeth dental problems	0.3	0.4	1.0	-1.0	-0.5
Weight	0.3	1.3	3.4	1.8	-0.8
Arm fat percentage (right)	0.3	1.1	2.7	1.6	0.9
Arm fat mass (right)	0.3	1.2	3.5	1.9	0.3
Pulse wave reflection index	0.3	0.3	0.9	0.3	-1.0
Qualifications: O levels/GCSEs or equivalent	0.3	0.4	0.9	0.9	0.6
High blood pressure (siblings)	0.3	0.4	0.6	0.8	0.7
Arm fat-free mass (right)	0.3	1.4	2.7	1.3	-1.6
Medication for pain relief, constipation, heartburn	0.3	0.5	1.2	1.1	0.6
Arm predicted mass (right)	0.3	1.7	3.2	1.4	-1.8
Number of full sisters	0.3	0.4	0.8	0.9	0.6
Arm fat percentage (left)	0.3	1.4	3.7	1.9	0.6
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	0.5	-0.7	0.7
Arm fat mass (left)	0.3	1.3	3.7	1.9	0.2
Guilty feelings	0.3	0.4	1.1	-1.1	0.3
Alcohol drinker status: Never	0.3	0.3	0.5	0.7	0.7
Deep venous thrombosis (DVT) (self-reported)	0.3	0.3	0.8	-0.9	0.5
Major Depression (MDD)	0.2	0.2	0.7	-0.2	0.8
Verbal and Numeric Reasoning (VNR)	0.2	0.4	1.0	0.6	1.0
Body Mass Index (BMI) (2010)	0.2	0.2	0.4	0.6	-0.6
Cardiovascular Disease	0.2	0.8	2.0	1.4	-0.5
Lung FEV1/FVC ratio	0.2	0.8	2.1	0.6	-1.4
Leg fat-free mass (left)	0.2	0.9	1.4	1.2	-1.2
Hand grip strength (right)	0.2	0.6	1.5	0.5	1.2
Average weekly fortified wine intake	0.2	0.2	0.6	-0.1	-0.8
Relative age voice broke	0.2	0.3	0.9	-0.9	0.3
High blood pressure (mother)	0.2	0.3	0.6	0.5	-0.8
Leg predicted mass (left)	0.2	0.9	1.4	1.1	-1.2
Alcohol usually taken with meals	0.2	0.3	0.6	-0.6	-0.8
Hearing difficulty/problems with background noise	0.2	0.3	0.5	0.5	-0.7
Pain all over the body in last month	0.2	0.2	0.6	0.8	0.2
Impedance of arm (right)	0.2	1.1	2.2	-1.5	1.1
Trunk fat-free mass	0.2	1.0	1.8	1.1	-1.3
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.4	1.1	-1.0	-0.3
Hair/balding pattern: Pattern 3	0.2	0.3	0.7	0.3	0.8
Lung cancer (father)	0.2	0.2	0.6	0.8	0.1
Trunk predicted mass	0.2	1.0	1.7	1.1	-1.3
Standing height	0.2	1.5	4.5	-0.3	-2.1
Breastfed as a baby	0.2	0.2	0.4	0.6	0.6
Blood clot in the leg (DVT)	0.2	0.2	0.6	-0.8	0.2
Headache pain in last month	0.2	0.3	0.7	-0.8	-0.3
Medication for cholesterol, blood pressure or diabetes	0.2	0.3	1.0	-1.0	-0.2
Glaucoma (self-reported)	0.2	0.2	0.7	-0.8	0.2
Shortness of breath walking on level ground	0.2	0.3	0.8	-0.1	0.9
Migraine (self-reported)	0.2	0.2	0.6	-0.8	-0.2
Comparative height size at age 10	0.2	1.0	2.4	1.6	-0.8
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.3	0.6	0.4	0.8
Whole body fat-free mass	0.2	1.1	2.2	1.1	-1.5
Leg fat-free mass (right)	0.2	1.1	2.2	1.0	-1.5
Commuting to job workplace: Walk	0.2	0.2	0.6	-0.8	0.3
Whole body water mass	0.2	1.0	2.3	0.8	-1.5
Leg predicted mass (right)	0.2	1.1	2.4	1.0	-1.5
Ever taken oral contraceptive pill	0.2	0.3	0.7	0.8	0.4
Hearing aid user	0.2	0.3	0.6	0.8	0.5
High cholesterol (Self-reported)	0.2	0.4	1.2	1.1	0.3
Basal metabolic rate	0.2	1.2	1.9	1.4	-1.2
Arm fat-free mass (left)	0.2	1.0	1.8	1.3	-1.0
Irritability	0.2	0.4	1.1	-0.1	-1.0
Unable to work because of sickness or disability	0.2	0.2	0.7	-0.8	-0.0
Arm predicted mass (left)	0.2	1.0	1.5	1.2	-1.2
Intelligence (Savage-Jansen 2018)	0.1	0.3	0.6	-0.4	0.8
Schizophrenia vs Biploar Disorder	0.1	0.2	0.4	-0.4	-0.6
Alzheimer’s Disease (in mother)	0.1	0.1	0.4	-0.6	0.1
Alzheimer’s Disease (including proxy)	0.1	0.2	0.5	0.1	-0.7
Breast Cancer	0.1	0.3	0.8	0.3	0.9
HbA1C	0.1	0.2	0.3	0.6	0.3
Hair Pigment	0.1	1.6	2.8	-1.5	-1.7
Number of treatments/medications taken	0.1	0.3	0.7	-0.2	0.9
Ever had hysterectomy (womb removed)	0.1	0.1	0.3	0.5	0.2
Systolic blood pressure, automated reading	0.1	0.4	0.7	-0.7	-0.8
Supplements: Zinc	0.1	0.1	0.4	-0.6	0.1
Fed-up feelings	0.1	0.2	0.5	-0.2	-0.7
Serious illness, injury or assault to yourself	0.1	0.1	0.2	-0.5	0.1
Supplements: Glucosamine	0.1	0.1	0.3	-0.5	-0.2
Hair/balding pattern: Pattern 2	0.1	0.2	0.5	0.0	0.7
Had other major operations	0.1	0.2	0.4	-0.3	0.6
Medication: Simvastatin	0.1	0.2	0.4	0.2	0.6
Fluid intelligence score	0.1	0.2	0.5	0.7	0.1
Medication: Cholesterol lowering	0.1	0.2	0.5	0.2	-0.7
Prospective memory result	0.1	0.1	0.3	-0.5	0.2
Impedance of arm (left)	0.1	0.5	0.9	-0.9	0.8
Peak expiratory flow (PEF)	0.1	0.3	0.8	0.9	0.0
Hypothyroidism/myxoedema (self-reported)	0.1	0.2	0.5	0.3	-0.7
Medication: Amlodipine	0.1	0.1	0.2	0.3	0.4
Chronic bronchitis/emphysema (mother)	0.1	0.1	0.1	-0.4	-0.4
Health satisfaction	0.1	0.1	0.2	0.4	0.2
Medication: Blood pressure	0.1	0.2	0.5	0.7	0.3
Overall health rating	0.1	0.3	0.7	-0.9	-0.2
Hypertension (Self-reported)	0.1	0.3	0.7	0.9	0.4
Illnesses of siblings: Diabetes	0.1	0.2	0.5	0.2	0.7
Eye problems/disorders: Cataract	0.1	0.1	0.3	0.3	0.6
Back pain experienced in last month	0.1	0.2	0.3	-0.5	0.5
Breast cancer (self-reported)	0.1	0.1	0.4	-0.7	-0.0
Medication: Aspirin	0.1	0.1	0.2	0.4	0.2
Eye problems/disorders: Glaucoma	0.1	0.1	0.2	-0.3	0.4
Medication: Atorvastatin	0.1	0.1	0.3	-0.2	-0.5
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0
Neuroticism (2016)	0.0	0.0	0.1	-0.1	-0.3
Systolic Blood Pressure	0.0	0.2	0.3	0.6	-0.3
Hypothyroidism (self reported)	0.0	0.0	0.0	-0.2	0.0
Tanning	0.0	0.0	0.1	-0.3	-0.1
Hand grip strength (left)	0.0	0.1	0.2	0.2	0.4
Pack years adult smoking proportion	0.0	0.1	0.2	0.4	-0.1
Impedance of leg (right)	0.0	0.2	0.4	0.4	0.6
High blood pressure	0.0	0.0	0.1	0.1	0.2
Medication: Levothyroxine sodium	0.0	0.0	0.1	-0.1	-0.4
Sitting height	0.0	0.3	0.7	0.8	-0.5
Impedance of leg (left)	0.0	0.1	0.2	0.5	0.2
Waist circumference	0.0	0.2	0.3	0.4	-0.6
Qualifications: A levels/AS levels or equivalent	0.0	0.1	0.2	-0.5	-0.2
Worry too long after embarrassment	0.0	0.0	0.0	0.2	-0.1
Leg pain on walking	0.0	0.0	0.1	-0.3	0.1
Medication: Aspirin	0.0	0.0	0.0	0.2	0.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.0	0.0	0.1	-0.4	-0.1
Qualifications: nursing, teaching	0.0	0.0	0.0	-0.1	-0.1
Tinnitus: Yes, now most or all of the time	0.0	0.0	0.0	0.2	-0.1
Pain type(s) experienced in last month: Hip pain	0.0	0.0	0.1	0.1	0.4
Diastolic blood pressure, automated reading	0.0	0.1	0.3	0.5	0.2
Vascular/heart problems diagnosed by doctor	0.0	0.1	0.3	-0.5	-0.3
Pack years of smoking	0.0	0.0	0.0	0.2	-0.2
Impedance of whole body	0.0	0.2	0.5	-0.3	0.7

Hub : Genes

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Trait associations