TWAS hub - PPP1R1B

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Heart Atrial Appendage	0.094	0.041	0.00089	0.041	NA	0.078	NA	0.064	0.0061	NA	0.00022	NA	0.00077
2	GTEx	Vagina	0.360	0.105	0.00100	0.000	NA	-0.012	NA	-0.010	0.3200	NA	0.79000	NA	0.60000

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Blood White Count	63.0	466.7	930.2	30.5	1.8
Respiratory disease	52.1	116.0	231.0	15.2	1.0
Asthma (self-reported)	47.0	93.7	185.0	13.6	1.5
Asthma	46.1	90.8	179.6	13.4	1.5
Allergy	26.0	59.8	116.6	-10.8	-1.7
Medication: Ventolin 100micrograms inhaler	18.9	24.2	47.1	6.9	1.2
HDL Cholesterol	15.6	26.0	48.3	-7.0	-1.9
Irritable Bowel Disease (IBD)	14.8	35.3	68.2	-8.3	-1.5
Hayfever, allergic rhinitis or eczema	12.4	27.0	53.4	7.3	0.7
Wheeze or whistling in the chest in last year	12.3	22.0	43.2	6.6	-0.9
Crohns Disease (2017)	11.4	25.0	49.3	-7.0	-0.9
Allergy or Eczema	10.3	27.1	54.2	7.4	-0.1
Ulcerative Colitis (UC)	9.1	17.0	32.3	-5.7	-1.3
Ulcerative Colitis	9.1	13.2	23.7	-4.9	-1.6
Primary Biliary Cirrhosis	8.6	12.2	24.5	-4.9	-0.2
Taking other prescription medications	6.7	10.3	20.5	4.5	0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	6.5	13.7	27.4	-5.2	-0.1
Crohns Disease (2012)	6.3	10.1	19.3	-4.4	1.0
Hayfever/allergic rhinitis (self-reported)	6.3	8.4	16.6	4.1	0.3
Lupus	5.9	8.9	17.3	-4.2	-0.8
Myopia	5.9	8.5	12.0	3.5	2.2
Ever had bowel cancer screening	5.7	6.7	9.4	-2.0	-3.1
Supplements: Vitamin C	5.6	6.6	10.7	3.3	1.6
Wears glasses or contact lenses	4.8	5.5	8.5	-2.9	-1.6
Chronic bronchitis/emphysema (father)	4.6	5.4	5.5	2.3	2.3
Tinnitus: Yes, but not now, but have in the past	4.5	4.9	6.9	-1.7	-2.6
Mouth/teeth dental problems: Dentures	4.5	7.7	14.8	3.8	0.7
Chest pain or discomfort	4.5	6.4	10.2	3.2	-1.6
Bipolar Disorder (2018)	4.4	7.0	11.2	3.3	1.7
Mouth/teeth dental problems: Mouth ulcers	4.4	7.0	12.0	-3.5	-1.4
Bipolar Disorder or Schizophrenia	4.2	10.2	14.6	3.8	2.4
Qualifications: NVQ or HND or HNC or equivalent	4.2	5.1	9.5	0.8	3.1
Friendships satisfaction	4.2	5.2	6.1	2.1	2.5
Number of self-reported non-cancer illnesses	4.2	7.2	14.4	3.8	0.3
Eye problems/disorders: None of the above	4.0	4.6	7.7	2.8	1.2
Basal cell carcinoma (self-reported)	4.0	4.7	8.8	3.0	0.8
Breast Cancer	3.9	9.3	16.6	1.4	4.1
Rheumatoid Arthritis	3.7	5.1	9.8	-3.1	-0.5
Emphysema/chronic bronchitis	3.6	4.1	6.8	2.6	1.2
Back pain experienced in last month	3.6	5.3	10.5	-0.1	-3.2
Father’s age at death	3.5	4.7	6.2	-1.8	-2.5
Number of operations (self-reported)	3.4	5.0	9.5	0.7	-3.1
Birth weight	3.3	7.1	13.3	0.9	3.6
Average weekly red wine intake	3.3	4.9	5.1	-2.1	-2.3
Lung FVC	3.2	16.3	31.7	-5.6	0.9
Ever depressed for a whole week	3.2	4.0	7.6	2.8	0.6
Alcohol intake frequency.	3.0	7.1	12.5	3.5	1.3
Blood Eosinophil Count	2.9	22.0	28.0	5.3	-4.0
Past tobacco smoking	2.9	5.3	8.0	-2.8	1.6
Ever smoked	2.9	5.1	9.0	3.0	-1.1
Alcohol usually taken with meals	2.7	4.3	7.5	-1.1	-2.7
Heart disease (mother)	2.7	3.3	6.5	2.6	-0.1
Long-standing illness, disability or infirmity	2.7	4.1	5.5	2.4	-1.6
Other serious medical condition/disability diagnosed by doctor	2.6	3.3	6.3	-0.6	-2.5
Family relationship satisfaction	2.6	3.2	5.4	2.3	1.0
Reason for reducing amount of alcohol drunk: Health precaution	2.5	3.0	3.5	-1.6	1.9
Medication: Seretide 50 evohaler	2.4	2.7	5.2	2.3	-0.6
Financial situation satisfaction	2.4	3.0	6.0	-0.3	-2.5
Type 2 Diabetes (T2D) (2018)	2.3	4.4	6.2	2.5	-1.6
Vitamin and mineral supplements	2.3	3.1	3.2	-1.8	-1.7
Number of full brothers	2.3	2.9	3.5	1.9	1.5
Schizophrenia (2014)	2.2	4.9	5.7	2.4	2.0
Medication for pain relief, constipation, heartburn	2.2	3.8	7.5	0.4	2.7
Medication: Metformin	2.1	3.0	3.9	2.0	-1.5
Townsend deprivation index at recruitment	2.1	3.0	5.0	2.2	0.9
Number of live births	2.1	3.0	3.7	1.9	-1.5
Alcohol drinker status: Previous	2.1	2.4	2.8	1.4	1.7
Type 2 Diabetes (T2D) (2012)	2.0	2.3	4.3	2.1	0.5
Smoking Status	2.0	4.9	9.6	3.1	-0.3
Serious illness, injury or assault to yourself	2.0	2.4	3.6	1.1	1.9
Illnesses of mother	2.0	2.5	5.0	-0.2	2.2
Medication: Aspirin	2.0	2.7	5.3	0.3	-2.3
Smoking status: Previous	2.0	3.0	3.1	1.7	-1.8
Commuting to job workplace: Public transport	2.0	2.4	3.4	-1.8	-1.2
Medication: Lisinopril	2.0	2.5	4.0	-2.0	-1.0
Schizophrenia (2018)	1.9	4.0	4.9	2.2	1.8
Major Depression (MDD)	1.9	2.4	2.7	1.4	1.6
HbA1C	1.9	2.1	3.5	-0.9	-1.9
Blood Red Count	1.9	18.7	35.6	6.0	1.3
Lung FEV1/FVC ratio	1.9	9.4	18.6	-4.3	0.5
Number of treatments/medications taken	1.9	3.5	6.5	2.5	-0.7
Impedance of arm (right)	1.9	9.0	17.9	4.2	0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	1.9	3.0	6.0	0.0	2.4
Shortness of breath walking on level ground	1.9	2.2	3.1	1.2	-1.8
Multivitamins +/- minerals	1.8	2.3	3.4	1.1	1.9
High blood pressure (mother)	1.8	2.5	4.8	-0.5	-2.2
Illnesses of siblings	1.8	2.6	2.9	-1.7	1.5
Suffer from ‘nerves’	1.8	2.8	5.5	-2.4	-0.4
Pain type(s) experienced in last month: Hip pain	1.8	2.3	3.1	-1.2	-1.8
Severe depression (siblings)	1.7	1.9	3.7	1.9	0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.7	1.9	3.9	0.0	-2.0
Diabetes diagnosed by doctor	1.7	2.7	3.5	1.9	-1.4
Hypothyroidism (self reported)	1.6	3.7	4.2	1.8	-2.0
Hand grip strength (right)	1.6	4.2	7.9	2.8	0.7
Frequency of tiredness / lethargy in last 2 weeks	1.6	2.5	5.0	0.2	-2.2
Forced expiratory volume in 1-second (FEV1)	1.6	5.4	10.8	-3.3	0.0
Impedance of arm (left)	1.6	7.3	14.5	3.8	-0.0
Gout (self-reported)	1.6	2.1	2.6	-1.6	-1.3
Pulse rate, automated reading	1.6	5.1	10.0	3.2	-0.5
Blood Platelet Count	1.5	17.1	21.9	-4.7	-3.5
Hand grip strength (left)	1.5	3.9	4.2	2.0	1.9
Falls in the last year	1.5	2.0	2.5	-1.6	-1.2
Forced expiratory volume in 1-second (FEV1), Best measure	1.5	4.8	9.5	-3.1	-0.1
Number of full sisters	1.5	1.8	2.9	0.9	1.7
Guilty feelings	1.5	2.3	2.3	1.5	1.5
Hearing aid user	1.5	1.7	2.5	-0.9	-1.6
Qualifications: None of the above	1.4	2.9	5.6	2.4	0.5
Diabetes (self-reported)	1.4	2.2	4.3	2.1	-0.3
Pulse rate	1.4	2.3	4.2	2.1	-0.6
Medication: Cholesterol lowering	1.4	2.2	4.2	-0.3	-2.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.4	1.6	3.0	1.7	0.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.4	1.7	3.2	1.8	-0.3
Average weekly beer plus cider intake	1.4	2.0	3.8	-2.0	0.4
Chronotype (morning person)	1.3	3.0	3.5	-1.6	-1.9
Age when periods started (menarche)	1.3	3.0	4.3	-1.3	2.1
Medication: Simvastatin	1.3	1.9	3.3	0.6	-1.8
Mouth/teeth dental problems: Bleeding gums	1.3	1.7	1.9	-1.4	-1.2
Illness, injury, bereavement, stress in last 2 years	1.3	1.6	2.1	1.1	-1.4
Illnesses of father: Heart disease	1.3	1.8	2.8	1.7	-0.9
Smoking status: Current	1.3	2.1	2.5	1.6	1.3
Illnesses of father: High blood pressure	1.3	1.7	3.2	-1.8	-0.4
Alcohol drinker status: Never	1.3	1.5	2.0	1.4	1.0
Age started oral contraceptive pill	1.3	1.6	3.2	-1.8	0.0
Supplements: Calcium	1.3	1.5	1.7	-1.1	1.3
Body Mass Index (BMI) (2010)	1.2	1.6	1.8	-1.3	1.2
Number of incorrect matches in round	1.2	2.1	3.0	1.7	1.1
Ever had hysterectomy (womb removed)	1.1	1.2	2.3	-0.3	-1.5
Current tobacco smoking	1.1	1.9	2.4	1.6	1.1
Nervous feelings	1.1	2.1	2.9	-1.1	1.7
Medication: Lansoprazole	1.1	1.2	1.9	-0.8	-1.4
Exposure to tobacco smoke outside home	1.1	1.5	1.8	1.1	1.3
Knee pain experienced in last month	1.1	1.8	2.8	-0.9	-1.7
Illnesses of siblings: Diabetes	1.1	1.4	2.6	0.4	-1.6
Irritability	1.1	1.8	3.1	-1.8	-0.7
Reaction Time	1.0	2.0	2.2	1.3	1.5
Mean Putamen Volume	1.0	1.2	1.3	1.1	1.0
Triglycerides	1.0	1.6	3.1	1.8	-0.2
Frequency of depressed mood in last 2 weeks	1.0	1.4	1.6	1.3	1.1
Medication for hormone replacement therapy	1.0	1.1	2.0	1.4	0.4
Medication: Levothyroxine sodium	1.0	1.7	2.4	1.5	-1.0
Time employed in main current job	1.0	1.1	1.3	-1.1	-1.0
Length of working week for main job	1.0	1.2	1.5	0.9	-1.2
Medication for cholesterol, blood pressure or diabetes	1.0	1.6	3.0	-0.5	1.7
Seen a psychiatrist for nerves, anxiety, tension or depression	1.0	1.3	2.4	0.5	1.6
Loneliness, isolation	1.0	1.3	2.7	-0.0	1.6
Pain experienced in last month	1.0	1.6	2.2	1.0	1.5
Heart attack/myocardial infarction (self-reported)	1.0	1.4	2.2	1.5	0.7
Deep venous thrombosis (DVT) (self-reported)	1.0	1.3	1.3	1.1	1.1
Coronary Artery Disease (CAD)	0.9	1.0	1.4	-0.8	-1.2
Eye problems/disorders: Diabetes related eye disease	0.9	1.0	1.3	-0.9	-1.1
Heart attack	0.9	1.1	1.9	1.4	0.5
Birth weight of first child	0.9	1.6	2.9	1.7	-0.6
Loud music exposure frequency	0.9	1.0	2.0	-1.4	-0.1
Medication: Amlodipine	0.9	1.3	2.4	0.4	-1.6
Qualifications: College or University degree	0.9	2.8	5.2	-2.3	-0.6
Angina (self-reported)	0.9	1.1	2.2	0.3	-1.5
Arm predicted mass (right)	0.9	4.6	8.1	-2.8	1.1
Risk taking	0.9	1.3	1.5	-1.0	-1.2
Impedance of whole body	0.9	4.5	8.8	3.0	-0.5
Worry (Nagel 2018)	0.8	1.7	2.7	-1.6	0.8
Hearing difficulty/problems: Yes	0.8	1.2	2.4	-0.3	-1.5
Angina	0.8	1.0	1.9	0.2	-1.4
Medication: Atenolol	0.8	1.0	1.1	0.9	-1.1
Had menopause	0.8	1.0	1.6	1.2	-0.6
Hypothyroidism/myxoedema (self-reported)	0.8	1.6	1.7	1.3	-1.2
Arm fat-free mass (right)	0.8	3.8	6.7	-2.6	1.0
Health satisfaction	0.8	1.1	2.2	-0.1	-1.5
Medication: Blood pressure	0.8	1.4	2.5	0.5	-1.6
Handedness (chirality/laterality): Left-handed	0.8	1.0	1.0	1.0	1.0
Medication: Aspirin	0.8	1.0	1.7	0.6	-1.3
Miserableness	0.8	1.4	2.6	1.6	-0.4
Mother’s age at death	0.8	1.0	1.9	-1.4	-0.1
Supplements: Fish oil (including cod liver oil)	0.8	1.0	1.9	1.4	-0.3
Alzheimer’s Disease (in father)	0.7	0.8	1.1	-0.6	-1.1
Alzheimer’s Disease (including proxy)	0.7	1.0	1.7	-1.3	-0.6
Medication: Co-codamol	0.7	0.8	1.6	-1.3	-0.2
Pack years adult smoking proportion	0.7	1.0	1.6	0.7	1.3
Forced vital capacity (FVC)	0.7	2.8	5.5	-2.3	0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.7	1.6	1.8	-1.3	1.2
Happiness	0.7	0.8	1.4	1.2	0.4
Mean time to correctly identify matches	0.7	1.4	2.3	1.5	0.7
Forced expiratory volume in 1-second (FEV1), predicted	0.7	1.4	2.8	1.7	-0.2
Eye problems/disorders: Cataract	0.7	0.8	0.9	-0.8	-0.9
Medication for cholesterol	0.7	1.1	2.2	-1.5	0.3
Medication: Paracetamol	0.7	1.1	1.8	-0.7	-1.3
Age at First Birth	0.6	0.9	1.2	-0.8	1.1
Ever used hormone-replacement therapy (HRT)	0.6	0.8	1.1	1.1	-0.7
Diabetes (father)	0.6	0.7	1.1	1.1	-0.6
Diabetes (mother)	0.6	0.7	1.3	-1.1	0.4
Maternal smoking around birth	0.6	0.9	1.5	0.4	-1.2
Fed-up feelings	0.6	1.1	2.1	-0.1	-1.5
Stomach or abdominal pain in last month	0.6	0.7	0.9	0.7	-1.0
Ever unenthusiastic/disinterested for a whole week	0.6	0.7	1.4	1.2	0.2
Hair/balding pattern: Pattern 4	0.6	1.5	1.9	1.4	1.1
Blood clot in the leg (DVT)	0.6	0.8	0.9	0.9	0.9
Number of children fathered	0.6	0.7	1.1	1.1	-0.5
Mouth/teeth dental problems: Loose teeth	0.6	0.7	1.3	0.4	-1.1
Medication: Ibuprofen	0.6	0.7	1.0	-0.7	-1.0
Medication: Allopurinol	0.6	0.8	1.4	-0.4	-1.2
Mood swings	0.6	1.1	2.1	-0.1	1.5
Osteoarthritis (self-reported)	0.6	0.7	0.9	-0.8	-0.9
Illnesses of father: None of the above (group 1)	0.6	0.7	1.5	-1.2	-0.0
Average weekly champagne plus white wine intake	0.6	0.9	1.3	-0.6	1.1
Medication: Bendroflumethiazide	0.6	0.8	1.1	1.1	-0.8
Medication: Omeprazole (e.g. Zanprol)	0.6	0.7	1.2	0.5	-1.1
Pack years of smoking	0.6	0.9	1.6	0.5	1.3
Prostate Cancer	0.5	0.7	1.0	0.6	1.0
Fasting Glucose	0.5	0.6	1.1	1.1	-0.1
Height	0.5	9.4	18.5	0.5	4.3
Impedance of leg (right)	0.5	2.5	4.1	2.0	-0.9
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	0.7	0.8	-0.7
Hearing difficulty/problems with background noise	0.5	0.7	1.2	-0.5	-1.1
Hair/balding pattern: Pattern 2	0.5	0.6	0.7	0.7	0.9
Trunk fat-free mass	0.5	2.7	2.8	-1.6	1.7
Alcohol intake versus 10 years previously	0.5	0.7	1.0	-1.0	0.6
Trunk predicted mass	0.5	2.6	2.7	-1.6	1.6
Tense / ‘highly strung’	0.5	0.9	1.1	-1.0	0.8
Whole body fat-free mass	0.5	2.7	2.8	-1.6	1.7
Whole body water mass	0.5	2.7	2.8	-1.7	1.6
Tinnitus: Yes, now most or all of the time	0.5	0.5	0.8	0.5	0.9
Arm fat-free mass (left)	0.5	2.6	3.3	-1.8	1.4
Cholesterol lowering medication	0.5	0.7	0.7	0.9	-0.8
Arm predicted mass (left)	0.5	2.6	3.7	-1.9	1.2
Schizophrenia vs Biploar Disorder	0.4	0.6	0.8	-0.9	-0.6
LDL Cholesterol	0.4	0.7	0.8	-0.8	-0.9
Average weekly spirits intake	0.4	0.4	0.7	0.4	-0.8
Sensitivity / hurt feelings	0.4	0.7	1.4	1.2	-0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.4	0.8	1.3	-1.1	0.6
Sitting height	0.4	3.2	6.2	-0.4	2.5
Had other major operations	0.4	0.4	0.9	0.1	-0.9
Neuroticism score	0.4	0.8	1.5	-0.0	1.2
Worrier / anxious feelings	0.4	0.7	0.9	0.7	0.9
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.4	0.9	-0.9	-0.0
Lung cancer (father)	0.4	0.5	0.9	-0.3	1.0
High blood pressure (siblings)	0.4	0.6	0.7	0.7	-0.8
Forced vital capacity (FVC), Best measure	0.4	1.6	3.1	-1.8	0.2
Medication: Omeprazole	0.4	0.5	1.0	-0.0	-1.0
Leg fat-free mass (right)	0.4	2.1	2.2	-1.5	1.4
Breast cancer (self-reported)	0.4	0.4	0.8	-0.1	0.9
Osteoporosis (self-reported)	0.4	0.5	0.5	-0.7	0.7
Leg predicted mass (right)	0.4	2.3	2.4	-1.5	1.5
High cholesterol (Self-reported)	0.4	0.7	1.3	0.4	-1.1
Basal metabolic rate	0.4	2.1	2.2	-1.4	1.5
Heart disease (siblings)	0.4	0.5	1.0	1.0	0.2
Systolic Blood Pressure	0.3	1.4	1.5	1.2	1.2
Financial difficulties in last 2 years	0.3	0.4	0.5	0.5	0.7
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.3	0.4	-0.5	-0.6
Depression (self-reported)	0.3	0.3	0.5	0.7	0.3
Prospective memory result	0.3	0.3	0.6	0.2	0.8
Pulse wave Arterial Stiffness index	0.3	0.4	0.8	0.9	-0.0
Breastfed as a baby	0.3	0.4	0.8	0.2	0.9
Peak expiratory flow (PEF)	0.3	0.6	0.9	0.6	-0.9
Pulse wave reflection index	0.3	0.4	0.7	-0.2	0.8
Ever highly irritable/argumentative for 2 days	0.3	0.4	0.6	0.8	0.3
Qualifications: O levels/GCSEs or equivalent	0.3	0.5	0.6	0.8	0.6
Glaucoma (self-reported)	0.3	0.3	0.6	-0.0	0.8
Pulse wave peak to peak time	0.3	0.4	0.6	-0.8	0.4
Overall health rating	0.3	0.7	1.1	0.5	-1.0
Had major operations	0.3	0.4	0.5	0.7	-0.5
Commuting to job workplace: Car/motor vehicle	0.3	0.3	0.6	-0.3	0.8
Medication: Blood pressure	0.3	0.5	1.0	1.0	0.3
Medication: Atorvastatin	0.3	0.4	0.8	-0.9	-0.0
Fractured/broken bones in last 5 years	0.3	0.3	0.7	-0.8	0.0
Commuting to job workplace: Cycle	0.3	0.3	0.4	-0.5	-0.7
Depressed Affect (Nagel 2018)	0.2	0.5	1.0	1.0	-0.1
Depression (Nagel 2018)	0.2	0.3	0.3	0.6	0.5
Alzheimer’s Disease (in mother)	0.2	0.2	0.3	-0.6	0.4
Ovarian Cancer	0.2	0.3	0.4	0.7	-0.4
Heel T-Score	0.2	1.5	3.0	-1.7	0.1
BMI	0.2	1.3	2.5	-1.6	-0.4
Leg fat-free mass (left)	0.2	1.2	1.6	-0.9	1.3
Impedance of leg (left)	0.2	0.9	1.3	1.1	-0.7
Leg predicted mass (left)	0.2	1.3	1.6	-1.0	1.3
Pain all over the body in last month	0.2	0.3	0.5	0.7	-0.1
Medication: Ramipril	0.2	0.2	0.3	0.6	0.4
Hip circumference	0.2	0.7	1.3	-1.1	0.2
Hair/balding pattern: Pattern 3	0.2	0.3	0.3	0.6	-0.5
Qualifications: A levels/AS levels or equivalent	0.2	0.4	0.5	0.7	0.6
Medication: Paracetamol	0.2	0.4	0.7	-0.2	-0.8
Chronic bronchitis/emphysema (mother)	0.2	0.2	0.5	0.7	0.1
Neck or shoulder pain in last month	0.2	0.3	0.5	0.4	-0.7
Hypertension (Self-reported)	0.2	0.5	0.9	1.0	-0.1
Qualifications: nursing, teaching	0.2	0.3	0.5	-0.7	-0.5
Commuting to job workplace: Walk	0.2	0.2	0.2	0.4	-0.4
Leg fat percentage (left)	0.2	0.6	0.9	-0.9	-0.5
Leg fat mass (left)	0.2	0.6	1.2	-1.1	-0.2
Neuroticism (Nagel 2018)	0.1	0.1	0.2	0.4	-0.3
Neuroticism	0.1	0.3	0.6	0.1	0.8
Relative age of first facial hair	0.1	0.2	0.4	0.1	0.7
Average weekly fortified wine intake	0.1	0.1	0.1	-0.4	0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.2	0.3	0.0	-0.6
Relative age voice broke	0.1	0.1	0.2	0.4	0.0
Qualifications: CSEs or equivalent	0.1	0.1	0.2	-0.1	-0.4
High blood pressure	0.1	0.2	0.3	0.6	-0.2
Supplements: Glucosamine	0.1	0.1	0.1	-0.4	0.3
Body mass index (BMI)	0.1	0.5	1.0	-1.0	-0.0
Waist circumference	0.1	0.5	1.0	-1.0	-0.2
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.1	0.1	-0.3	-0.3
Mouth/teeth dental problems	0.1	0.2	0.4	0.2	0.6
Fluid intelligence score	0.1	0.3	0.6	-0.7	-0.1
Weight	0.1	0.7	1.0	-1.0	0.6
Arm fat percentage (right)	0.1	0.5	0.8	0.9	0.5
Noisy workplace	0.1	0.1	0.2	-0.0	-0.4
Standing height	0.1	0.9	1.8	-0.2	1.4
Leg fat percentage (right)	0.1	0.3	0.4	-0.4	-0.6
Comparative body size at age 10	0.1	0.4	0.5	-0.5	-0.7
Leg fat mass (right)	0.1	0.3	0.6	-0.8	-0.3
Comparative height size at age 10	0.1	0.6	1.1	1.0	0.4
Age at last live birth	0.1	0.1	0.2	-0.4	-0.3
Leg pain on walking	0.1	0.2	0.2	-0.4	-0.4
Arm fat percentage (left)	0.1	0.3	0.5	0.7	0.3
Mineral and other dietary supplements	0.1	0.1	0.2	0.1	0.5
Ever taken oral contraceptive pill	0.1	0.1	0.1	0.2	0.3
Ever had prostate specific antigen (PSA) test	0.1	0.1	0.1	0.3	-0.2
Vascular/heart problems diagnosed by doctor	0.1	0.2	0.4	-0.6	0.4
Intelligence (Savage-Jansen 2018)	0.0	0.0	0.0	0.2	-0.1
Verbal and Numeric Reasoning (VNR)	0.0	0.0	0.1	-0.1	-0.3
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0
Neuroticism (2016)	0.0	0.1	0.1	0.3	0.2
Waist Hip Ratio (WHR)	0.0	0.1	0.2	-0.4	-0.3
Cardiovascular Disease	0.0	0.0	0.0	-0.1	0.1
Hair Pigment	0.0	1.1	1.7	-1.3	-0.6
Tanning	0.0	0.3	0.4	0.7	-0.4
Systolic blood pressure, automated reading	0.0	0.1	0.2	-0.5	0.2
Supplements: Zinc	0.0	0.0	0.0	-0.2	0.1
Trunk fat percentage	0.0	0.1	0.1	0.4	0.2
Bilateral oophorectomy (both ovaries removed)	0.0	0.0	0.1	0.2	-0.3
Trunk fat mass	0.0	0.2	0.3	-0.2	0.6
Arm fat mass (right)	0.0	0.2	0.3	-0.1	0.6
Exposure to tobacco smoke at home	0.0	0.0	0.0	-0.2	-0.1
Headache pain in last month	0.0	0.1	0.1	0.1	-0.3
Body fat percentage	0.0	0.0	0.0	0.1	-0.2
Worry too long after embarrassment	0.0	0.1	0.1	0.2	0.2
Age at first live birth	0.0	0.0	0.0	-0.0	0.1
Migraine (self-reported)	0.0	0.0	0.0	0.2	0.1
Whole body fat mass	0.0	0.1	0.1	-0.4	0.2
Ever had stillbirth, spontaneous miscarriage or termination	0.0	0.0	0.0	0.1	-0.2
Medication: Gliclazide	0.0	0.0	0.1	-0.0	-0.2
Arm fat mass (left)	0.0	0.1	0.2	-0.2	0.5
Eye problems/disorders: Glaucoma	0.0	0.0	0.1	0.2	-0.1
Diastolic blood pressure, automated reading	0.0	0.0	0.1	-0.3	0.1
Unable to work because of sickness or disability	0.0	0.0	0.0	-0.0	-0.1

Hub : Genes

PPP1R1B

Models

Trait associations