[Hub]/) : Traits : Heel T-Score : ← →

chr7:90,874,777-93,160,671

Best TWAS P=1.58e-37 · Best GWAS P=2.69e-39 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	CDK6	0.12	0.10	lasso	2	0.10	1.9e-12	-11.9	-11.9	1.5e-32	0.80	0.98	0.02	TRUE
2	CommonMind	Brain Pre-frontal Cortex	CYP51A1	0.05	0.08	lasso	5	0.06	2.4e-08	-6.3	6.2	5.0e-10	-0.21	1.00	0.00	FALSE
3	CommonMind	Brain Pre-frontal Cortex	KRIT1	0.04	0.01	blup	318	0.02	1.2e-03	-6.2	7.1	1.6e-12	-0.24	0.60	0.01	TRUE
4	GTEx	Adipose Subcutaneous	GATAD1	0.21	0.14	enet	10	0.16	3.4e-13	-7.1	5.7	9.3e-09	-0.50	1.00	0.00	FALSE
5	GTEx	Adipose Visceral Omentum	GATAD1	0.12	0.08	lasso	5	0.06	7.5e-04	-7.1	7.7	1.6e-14	-0.58	0.68	0.21	FALSE
6	GTEx	Adrenal Gland	GATAD1	0.40	0.22	lasso	7	0.25	2.0e-09	-7.1	8.9	5.1e-19	-0.63	0.59	0.19	FALSE
7	GTEx	Artery Aorta	KRIT1	0.15	0.00	enet	24	0.03	1.3e-02	1.0	8.6	7.2e-18	-0.34	0.12	0.11	FALSE
8	GTEx	Artery Aorta	GATAD1	0.09	0.08	enet	4	0.07	7.4e-05	-7.1	7.3	3.0e-13	-0.56	0.45	0.19	FALSE
9	GTEx	Artery Aorta	AC000120.7	0.06	0.09	lasso	4	0.08	3.4e-05	-6.3	6.3	2.4e-10	-0.19	0.93	0.00	FALSE
10	GTEx	Artery Coronary	GATAD1	0.12	0.15	lasso	3	0.12	8.0e-05	-6.9	7.2	5.9e-13	-0.61	0.19	0.20	FALSE
11	GTEx	Artery Coronary	AC000120.7	0.07	0.04	lasso	4	0.02	6.8e-02	-6.4	6.5	5.6e-11	-0.24	0.20	0.04	FALSE
12	GTEx	Artery Tibial	GATAD1	0.14	0.04	enet	17	0.04	4.1e-04	-7.1	6.8	1.3e-11	-0.52	0.68	0.13	FALSE
13	GTEx	Artery Tibial	AC000120.7	0.08	0.06	lasso	4	0.06	3.2e-05	-5.7	6.8	1.1e-11	-0.29	0.96	0.00	TRUE
14	GTEx	Brain Caudate basal ganglia	GATAD1	0.21	0.09	lasso	4	0.08	2.3e-03	-6.4	8.3	1.2e-16	-0.63	0.04	0.58	FALSE
15	GTEx	Brain Cortex	AC000120.7	0.12	0.08	enet	16	0.07	7.0e-03	-6.3	7.3	2.7e-13	-0.30	0.13	0.05	TRUE
16	GTEx	Cells Transformed fibroblasts	GATAD1	0.23	0.20	lasso	4	0.22	1.4e-16	-7.1	8.9	6.6e-19	-0.73	0.88	0.12	FALSE
17	GTEx	Cells Transformed fibroblasts	AC000120.7	0.04	0.05	lasso	4	0.04	5.2e-04	-6.4	6.6	4.4e-11	-0.21	0.82	0.01	FALSE
18	GTEx	Colon Transverse	GATAD1	0.13	0.00	enet	16	0.05	3.0e-03	-7.1	9.3	1.9e-20	-0.58	0.13	0.46	FALSE
19	GTEx	Colon Transverse	AC000120.7	0.09	0.04	lasso	5	0.01	9.4e-02	-6.3	6.3	3.7e-10	-0.18	0.23	0.05	FALSE
20	GTEx	Esophagus Mucosa	AKAP9	0.04	0.03	lasso	15	0.02	2.7e-02	-6.3	-6.2	4.3e-10	0.19	0.76	0.02	FALSE
21	GTEx	Esophagus Mucosa	GATAD1	0.16	0.05	enet	16	0.08	7.3e-06	-7.1	7.8	5.5e-15	-0.56	0.58	0.32	FALSE
22	GTEx	Esophagus Muscularis	GATAD1	0.18	0.10	enet	33	0.13	1.6e-08	-7.1	7.0	1.7e-12	-0.46	0.97	0.01	FALSE
23	GTEx	Esophagus Muscularis	FAM133B	0.07	0.01	enet	2	0.01	1.2e-01	7.3	7.7	1.1e-14	-0.67	0.08	0.30	FALSE
24	GTEx	Heart Atrial Appendage	AKAP9	0.06	0.01	enet	11	0.02	4.5e-02	-5.9	5.7	1.0e-08	-0.21	0.31	0.03	FALSE
25	GTEx	Lung	GATAD1	0.15	0.12	lasso	2	0.11	1.1e-08	-7.1	7.0	3.0e-12	-0.60	0.98	0.01	FALSE
26	GTEx	Lung	AC000120.7	0.04	0.03	lasso	3	0.01	4.8e-02	-6.3	6.4	1.6e-10	-0.20	0.46	0.02	FALSE
27	GTEx	Muscle Skeletal	CYP51A1	0.10	0.18	enet	21	0.17	5.0e-16	-6.2	6.8	1.4e-11	-0.22	1.00	0.00	FALSE
28	GTEx	Muscle Skeletal	PEX1	0.06	0.03	lasso	5	0.02	2.7e-03	-6.5	-6.9	4.5e-12	0.46	0.18	0.70	FALSE
29	GTEx	Muscle Skeletal	GATAD1	0.05	0.00	enet	13	0.01	2.4e-02	-4.2	8.5	2.7e-17	-0.51	0.45	0.09	FALSE
30	GTEx	Nerve Tibial	ANKIB1	0.04	0.04	enet	2	0.02	8.5e-03	-5.6	6.2	6.2e-10	-0.25	0.42	0.06	FALSE
31	GTEx	Nerve Tibial	AKAP9	0.03	0.05	lasso	2	0.03	2.7e-03	-6.1	-6.1	8.6e-10	0.20	0.46	0.03	FALSE
32	GTEx	Nerve Tibial	GATAD1	0.30	0.19	lasso	5	0.23	1.8e-16	-7.1	6.1	8.6e-10	-0.52	1.00	0.00	FALSE
33	GTEx	Pancreas	GATAD1	0.12	0.13	lasso	2	0.14	2.0e-06	-7.1	6.2	7.3e-10	-0.57	0.18	0.47	FALSE
34	GTEx	Pancreas	AC000120.7	0.05	0.03	enet	12	0.02	4.4e-02	-5.2	5.5	2.8e-08	-0.21	0.30	0.03	FALSE
35	GTEx	Prostate	AC000120.7	0.13	0.09	lasso	3	0.09	2.8e-03	-6.2	6.2	4.2e-10	-0.20	0.13	0.05	FALSE
36	GTEx	Skin Not Sun Exposed Suprapubic	GATAD1	0.22	0.27	lasso	4	0.26	1.1e-14	-7.1	7.3	3.4e-13	-0.60	1.00	0.00	FALSE
37	GTEx	Skin Sun Exposed Lower leg	PEX1	0.18	0.06	enet	41	0.03	1.5e-03	6.1	7.0	2.0e-12	-0.53	0.21	0.14	FALSE
38	GTEx	Skin Sun Exposed Lower leg	GATAD1	0.30	0.10	enet	14	0.16	7.0e-13	-7.1	7.0	2.1e-12	-0.50	1.00	0.00	FALSE
39	GTEx	Skin Sun Exposed Lower leg	AC000120.7	0.06	0.00	enet	24	0.00	7.9e-01	-2.2	5.8	5.8e-09	-0.25	0.14	0.05	FALSE
40	GTEx	Spleen	PEX1	0.18	0.00	enet	38	0.05	2.4e-02	-5.8	7.5	6.2e-14	-0.36	0.07	0.16	FALSE
41	GTEx	Spleen	AC000120.7	0.10	0.07	lasso	5	0.04	3.9e-02	-6.3	6.2	6.2e-10	-0.20	0.15	0.06	FALSE
42	GTEx	Stomach	GATAD1	0.30	0.13	lasso	5	0.15	8.6e-08	-7.1	7.2	4.0e-13	-0.59	0.97	0.01	FALSE
43	GTEx	Testis	CDK6	0.10	0.10	lasso	3	0.09	8.0e-05	-12.6	12.8	1.6e-37	-0.88	0.02	0.97	TRUE
44	GTEx	Thyroid	GATAD1	0.18	0.06	lasso	4	0.06	3.3e-05	-7.1	7.1	9.1e-13	-0.56	0.97	0.01	FALSE
45	METSIM	Adipose	GATAD1	0.10	0.05	lasso	7	0.06	9.4e-10	-4.2	6.5	9.5e-11	-0.47	0.96	0.04	TRUE
46	ROSMAP	Brain Pre-frontal Cortex	CYP51A1	0.04	0.02	blup	287	0.03	4.7e-05	-6.4	5.2	2.0e-07	-0.12	0.95	0.00	FALSE
47	ROSMAP	Brain Pre-frontal Cortex	KRIT1	0.04	0.03	bslmm	311	0.01	9.0e-03	-5.8	-7.8	7.3e-15	0.45	0.76	0.03	FALSE
48	ROSMAP	Brain Pre-frontal Cortex	GATAD1	0.17	0.15	lasso	4	0.16	6.0e-20	-7.1	7.3	2.0e-13	-0.58	1.00	0.00	FALSE
49	YFS	Blood	CYP51A1	0.03	0.06	blup	288	0.05	1.2e-16	-6.3	7.5	8.6e-14	-0.30	1.00	0.00	FALSE
50	YFS	Blood	GATAD1	0.01	0.01	blup	297	0.01	5.1e-04	-7.1	8.7	4.2e-18	-0.57	0.75	0.08	FALSE
51	The Cancer Genome Atlas	Breast Invasive Carcinoma	CYP51A1	0.01	0.02	blup	51	0.02	2.0e-04	-6.4	6.3	2.4e-10	-0.21	0.03	0.95	FALSE
52	The Cancer Genome Atlas	Breast Invasive Carcinoma	GATAD1	0.06	0.04	lasso	6	0.04	2.2e-09	-7.2	6.7	2.4e-11	-0.45	0.00	1.00	FALSE
53	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CYP51A1	0.07	0.04	lasso	2	0.04	4.3e-05	-5.5	5.6	1.8e-08	-0.25	0.21	0.76	FALSE
54	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CYP51A1	0.04	0.05	blup	51	0.05	9.4e-07	-6.2	6.4	2.0e-10	-0.21	0.04	0.96	FALSE
55	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	GATAD1	0.04	0.04	lasso	2	0.03	2.8e-04	-7.2	7.0	2.5e-12	-0.53	0.00	0.99	FALSE
56	The Cancer Genome Atlas	Brain Lower Grade Glioma	CYP51A1	0.01	0.01	blup	51	0.01	1.2e-02	-6.3	6.3	2.3e-10	-0.21	0.03	0.74	FALSE
57	The Cancer Genome Atlas	Lung Adenocarcinoma	CYP51A1	0.03	0.03	enet	12	0.03	1.2e-04	-5.5	5.9	4.1e-09	-0.24	0.06	0.86	FALSE
58	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	LOC401387	0.04	0.00	lasso	1	0.00	1.6e-01	-6.2	-6.2	4.7e-10	0.22	0.02	0.75	FALSE
59	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	C7orf64	0.06	0.02	blup	36	0.02	6.0e-02	-6.5	-5.6	2.1e-08	0.46	0.02	0.52	FALSE
60	The Cancer Genome Atlas	Prostate Adenocarcinoma	MTERF	0.03	0.03	blup	47	0.04	1.2e-04	-5.0	-5.5	3.3e-08	0.21	0.04	0.93	FALSE