Hub : Genes

LOC401387

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 TCGA Ovarian Serous Cystadenocarcinoma 0.037 0.031 0.0067 -0.002 -0.003 -0.003 NA 0.004 0.4500 0.54 0.540 NA 0.160
2 TCGA Soft Tissue Sarcoma 0.077 0.065 0.0068 0.036 0.002 0.024 NA 0.011 0.0033 0.22 0.014 NA 0.069

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 0.6 0.9 1.8 -1.3 0.2
Bipolar Disorder or Schizophrenia 0.1 0.2 0.4 0.1 -0.7
Depressed Affect (Nagel 2018) 0.5 1.1 1.1 -1.0 1.0
Depression (Nagel 2018) 1.1 1.6 1.9 -1.4 -1.2
Intelligence (Savage-Jansen 2018) 0.1 0.3 0.6 0.8 -0.2
Neuroticism (Nagel 2018) 0.1 0.2 0.3 0.4 -0.6
Schizophrenia (2018) 0.6 1.2 1.4 1.2 -1.0
Schizophrenia vs Biploar Disorder 5.8 7.6 9.2 3.0 -2.4
Worry (Nagel 2018) 0.2 0.4 0.7 0.2 -0.9
Alzheimer’s Disease (in mother) 9.9 11.6 16.1 -2.7 4.0
Alzheimer’s Disease (in father) 1.1 1.2 2.4 -1.5 0.1
Alzheimer’s Disease (including proxy) 10.0 14.4 15.3 -3.7 3.9
Crohns Disease (2017) 0.5 1.0 2.1 -1.4 0.1
Irritable Bowel Disease (IBD) 1.1 2.6 2.7 -1.5 1.7
Ulcerative Colitis (UC) 0.5 0.9 1.7 -0.4 1.3
Major Depression (MDD) 1.7 2.0 4.0 -2.0 -0.1
Reaction Time 1.0 2.0 3.7 1.9 -0.5
Verbal and Numeric Reasoning (VNR) 0.2 0.5 0.8 0.9 0.3
Breast Cancer 12.7 30.5 35.8 -6.0 5.0
Ovarian Cancer 0.5 0.6 0.9 0.9 -0.6
Prostate Cancer 0.0 0.0 0.0 0.0 0.0
Age at First Birth 0.7 1.0 1.2 0.9 -1.1
Bipolar Disorder (2011) 0.0 0.0 0.0 0.0 -0.1
Body Mass Index (BMI) (2010) 0.2 0.2 0.3 0.5 0.5
Coronary Artery Disease (CAD) 0.6 0.7 1.0 1.0 -0.6
Crohns Disease (2012) 0.6 0.9 1.9 -1.4 0.0
Mean Putamen Volume 2.9 3.3 5.5 2.4 -1.0
Fasting Glucose 0.1 0.1 0.3 -0.1 0.5
HbA1C 0.3 0.4 0.4 -0.6 0.6
HDL Cholesterol 0.4 0.7 1.2 0.5 -1.1
LDL Cholesterol 0.7 1.2 1.4 -1.2 0.9
Lupus 0.6 0.9 1.8 -1.3 0.3
Neuroticism (2016) 1.9 2.7 5.5 -2.3 0.1
Primary Biliary Cirrhosis 0.5 0.7 1.1 1.1 -0.6
Rheumatoid Arthritis 0.6 0.8 1.7 -0.2 1.3
Schizophrenia (2014) 0.9 2.1 2.3 1.5 -1.3
Triglycerides 0.7 1.1 1.6 -0.8 1.3
Type 2 Diabetes (T2D) (2012) 0.1 0.1 0.2 0.3 0.4
Ulcerative Colitis 1.0 1.4 1.5 -1.1 1.2
Blood Eosinophil Count 3.8 29.0 38.9 6.2 -4.4
Blood Platelet Count 1.0 12.0 20.3 -4.5 1.9
Blood Red Count 4.2 40.6 65.8 -8.1 3.9
Blood White Count 0.6 4.8 5.2 -2.3 2.1
Heel T-Score 3.2 25.2 38.8 -6.2 3.4
BMI 0.0 0.0 0.1 0.1 -0.2
Height 2.0 39.5 70.9 8.4 -2.8
Waist Hip Ratio (WHR) 0.2 1.0 1.4 0.8 -1.2
Systolic Blood Pressure 2.4 11.8 23.1 -4.8 0.6
Smoking Status 0.1 0.3 0.4 0.4 0.6
Allergy or Eczema 0.3 0.7 1.3 -1.2 -0.1
Cardiovascular Disease 0.5 1.6 3.1 -1.8 0.1
Hypothyroidism (self reported) 0.5 1.2 1.6 0.9 -1.2
Respiratory disease 0.2 0.4 0.7 -0.9 0.1
Type 2 Diabetes (T2D) (2018) 3.0 5.7 6.7 -2.6 2.2
Lung FEV1/FVC ratio 0.0 0.1 0.1 -0.3 0.1
Lung FVC 2.4 12.0 16.4 -4.0 2.8
Neuroticism 0.0 0.1 0.1 -0.2 -0.2
Chronotype (morning person) 3.3 7.6 9.9 -3.2 2.3
Hair Pigment 0.3 8.3 15.3 -3.9 1.1
Tanning 0.0 0.4 0.8 -0.9 0.3
Hand grip strength (left) 0.0 0.1 0.1 0.2 0.3
Number of treatments/medications taken 1.4 2.6 4.4 -2.1 0.9
Average weekly spirits intake 0.2 0.3 0.4 -0.6 -0.5
Sensitivity / hurt feelings 0.4 0.7 1.2 -0.3 -1.1
Frequency of depressed mood in last 2 weeks 0.7 1.0 1.4 -1.2 -0.7
Hearing difficulty/problems: Yes 0.1 0.2 0.3 0.5 -0.4
Relative age of first facial hair 0.5 1.0 2.0 1.4 0.1
Other serious medical condition/disability diagnosed by doctor 1.0 1.3 2.5 -1.6 0.2
Ever used hormone-replacement therapy (HRT) 5.6 7.1 12.2 -3.5 1.4
Ever had hysterectomy (womb removed) 1.8 2.1 4.1 -2.0 -0.2
Systolic blood pressure, automated reading 2.4 6.9 13.7 -3.7 -0.1
Eye problems/disorders: Diabetes related eye disease 2.1 2.3 3.2 -1.8 1.2
Angina 1.2 1.6 2.3 -1.5 0.9
Medication for hormone replacement therapy 9.6 10.7 11.5 -3.4 3.2
Vitamin and mineral supplements 1.7 2.3 3.2 1.8 -1.2
Supplements: Zinc 2.2 2.4 4.5 -2.1 0.4
Medication: Co-codamol 0.5 0.6 1.1 -1.1 -0.4
Medication: Metformin 4.6 6.5 8.5 -2.9 2.1
Diabetes (father) 0.1 0.1 0.2 -0.5 -0.1
Diabetes (mother) 1.4 1.7 1.8 -1.3 1.3
Severe depression (siblings) 1.7 1.9 3.2 -1.8 0.8
Pack years adult smoking proportion 0.3 0.5 0.8 0.4 -0.9
Impedance of leg (right) 0.0 0.2 0.3 -0.6 0.0
Leg fat-free mass (left) 1.8 9.3 15.9 4.0 -1.6
Trunk fat percentage 0.1 0.3 0.5 0.2 -0.7
Hand grip strength (right) 0.0 0.0 0.0 0.1 -0.1
Townsend deprivation index at recruitment 0.3 0.4 0.7 0.8 -0.3
Current tobacco smoking 0.0 0.0 0.0 -0.0 0.2
Average weekly fortified wine intake 0.5 0.6 0.9 -1.0 0.5
Maternal smoking around birth 0.3 0.4 0.7 0.8 -0.4
Fed-up feelings 0.2 0.3 0.6 0.1 0.7
Frequency of unenthusiasm / disinterest in last 2 weeks 0.8 1.1 2.1 0.3 -1.4
Relative age voice broke 0.4 0.6 1.2 1.1 0.0
Taking other prescription medications 0.4 0.6 1.2 -0.2 -1.1
Age when periods started (menarche) 0.4 1.0 1.6 1.2 -0.6
Bilateral oophorectomy (both ovaries removed) 6.6 7.6 13.7 -3.7 1.3
Heel bone mineral density (BMD) T-score, automated (left) 0.7 1.5 2.8 -1.7 0.5
Tinnitus: Yes, but not now, but have in the past 0.7 0.7 1.1 0.5 -1.1
Qualifications: CSEs or equivalent 1.6 2.1 3.2 1.0 -1.8
Serious illness, injury or assault to yourself 2.1 2.6 3.9 -2.0 1.1
High blood pressure 0.7 1.9 3.8 -1.9 -0.0
Hayfever, allergic rhinitis or eczema 0.0 0.1 0.1 -0.3 0.2
Multivitamins +/- minerals 2.9 3.7 4.8 -2.2 1.6
Stomach or abdominal pain in last month 1.3 1.6 2.6 -1.6 -0.8
Supplements: Glucosamine 0.9 1.1 2.2 -1.5 -0.1
Diverticular disease/diverticulitis (self-reported) 1.7 2.0 2.8 -1.7 1.1
Medication: Atenolol 0.2 0.3 0.3 -0.5 -0.5
Medication: Levothyroxine sodium 4.0 6.8 6.9 2.6 -2.6
Sitting height 1.1 7.8 14.6 3.8 -1.0
Chronic bronchitis/emphysema (father) 0.6 0.7 1.2 0.4 -1.1
High blood pressure (mother) 0.5 0.7 1.4 -0.1 -1.2
Body mass index (BMI) 0.0 0.2 0.2 0.3 -0.5
Impedance of leg (left) 0.2 1.0 1.8 -1.3 0.3
Leg predicted mass (left) 1.8 9.7 16.5 4.1 -1.7
Trunk fat mass 0.3 1.4 1.9 1.4 -0.9
Waist circumference 0.4 1.3 1.8 1.3 -0.9
Number of incorrect matches in round 1.6 2.7 5.1 -2.3 0.5
Past tobacco smoking 0.5 0.9 1.1 -1.1 0.8
Alcohol usually taken with meals 1.2 2.0 3.9 -2.0 0.3
Nervous feelings 1.0 1.9 2.4 1.5 -1.2
Frequency of tenseness / restlessness in last 2 weeks 0.3 0.4 0.7 -0.8 -0.3
Hearing difficulty/problems with background noise 0.4 0.7 0.7 0.8 0.8
Hair/balding pattern: Pattern 2 3.1 4.0 4.7 1.8 -2.2
Had menopause 0.2 0.3 0.4 -0.7 0.3
Had other major operations 1.4 1.7 3.1 -1.8 0.4
Forced vital capacity (FVC) 0.3 1.3 1.9 -0.9 1.4
Heel bone mineral density (BMD) T-score, automated (right) 1.3 2.9 5.6 -2.4 0.5
Ever unenthusiastic/disinterested for a whole week 4.7 5.8 10.2 -3.2 1.2
Qualifications: None of the above 2.2 4.7 5.9 -2.4 1.9
Financial difficulties in last 2 years 7.8 10.5 12.8 -3.6 2.8
Mouth/teeth dental problems 1.8 2.8 3.9 -1.3 2.0
Heart attack 0.3 0.4 0.5 -0.7 -0.6
Allergy 0.4 0.8 0.9 0.9 -0.9
Pain all over the body in last month 0.3 0.3 0.6 0.0 0.8
Diabetes (self-reported) 4.0 6.1 9.4 -3.1 1.7
Hayfever/allergic rhinitis (self-reported) 0.6 0.8 1.6 -1.3 0.2
Medication: Ramipril 0.4 0.5 0.9 -1.0 -0.1
Medication: Simvastatin 0.3 0.4 0.7 -0.9 -0.2
Fluid intelligence score 0.5 1.1 2.1 1.4 0.2
Illnesses of siblings 1.2 1.7 3.0 1.7 -0.6
Neuroticism score 0.1 0.3 0.3 -0.6 -0.5
Weight 0.8 3.9 6.6 2.6 -1.2
Impedance of arm (right) 0.0 0.0 0.0 -0.2 0.1
Arm fat percentage (right) 0.1 0.2 0.4 0.3 -0.6
Trunk fat-free mass 2.3 13.0 23.3 4.8 -1.6
Hip circumference 0.4 1.7 2.8 1.7 -0.8
Time employed in main current job 0.1 0.1 0.2 0.5 0.0
Alcohol intake versus 10 years previously 4.8 7.2 11.0 -3.3 1.9
Father’s age at death 1.3 1.7 2.4 -1.6 1.0
Worrier / anxious feelings 0.1 0.2 0.3 -0.2 -0.5
Frequency of tiredness / lethargy in last 2 weeks 0.6 0.9 0.9 -1.0 -0.9
Falls in the last year 0.6 0.9 0.9 -1.0 0.9
Hair/balding pattern: Pattern 3 0.3 0.4 0.7 0.4 -0.9
Number of live births 0.4 0.5 0.6 -0.7 0.7
Forced expiratory volume in 1-second (FEV1) 0.3 1.2 1.5 -0.9 1.2
Pulse rate 0.4 0.6 1.2 0.1 1.1
Happiness 1.3 1.5 2.7 -1.6 0.6
Noisy workplace 0.9 1.2 2.3 -1.5 -0.1
Qualifications: A levels/AS levels or equivalent 0.1 0.3 0.4 -0.4 -0.7
Serious illness, injury or assault of a close relative in last 2 years 2.4 2.8 3.4 -1.8 1.5
Mouth/teeth dental problems: Dentures 1.5 2.5 2.9 -1.7 1.5
Asthma 1.3 2.6 2.6 -1.6 1.6
Medication: Ibuprofen (e.g. Nurofen) 1.1 1.4 2.1 0.9 -1.5
Medication: Cholesterol lowering 0.9 1.5 2.9 -1.7 -0.0
Depression (self-reported) 0.4 0.4 0.6 -0.8 -0.5
Medication: Lansoprazole 8.6 9.8 15.5 -3.9 2.0
Prospective memory result 0.1 0.2 0.3 -0.2 -0.6
Lung cancer (father) 0.9 1.0 2.0 1.4 -0.2
Illnesses of mother 0.2 0.2 0.3 0.4 -0.5
Forced expiratory volume in 1-second (FEV1), Best measure 0.4 1.1 2.0 -0.5 1.4
Pulse wave Arterial Stiffness index 0.4 0.4 0.9 0.1 -0.9
Impedance of arm (left) 0.1 0.4 0.7 -0.8 0.3
Arm fat mass (right) 0.4 1.5 2.1 1.5 -0.9
Trunk predicted mass 2.2 12.8 23.1 4.8 -1.6
Standing height 1.5 14.4 26.4 5.1 -1.6
Length of working week for main job 3.2 3.6 5.7 -2.4 1.2
Exposure to tobacco smoke at home 1.2 1.3 2.6 -0.0 1.6
Breastfed as a baby 0.9 1.1 2.2 -0.3 -1.5
Tense / ‘highly strung’ 0.9 1.4 2.8 -1.7 -0.2
Seen doctor (GP) for nerves, anxiety, tension or depression 0.5 0.8 1.5 -1.2 -0.3
Hair/balding pattern: Pattern 4 1.0 2.5 3.8 -1.9 1.1
Birth weight of first child 1.1 2.1 3.3 1.8 -0.9
Peak expiratory flow (PEF) 0.6 1.3 2.7 -1.6 0.1
Pulse wave reflection index 0.9 1.1 2.2 -0.2 -1.5
Ever highly irritable/argumentative for 2 days 0.8 0.9 1.4 -1.2 0.7
Loud music exposure frequency 2.1 2.3 3.0 1.2 -1.7
Qualifications: O levels/GCSEs or equivalent 1.3 2.1 3.1 1.8 -1.1
Mouth/teeth dental problems: Bleeding gums 10.2 13.2 15.1 3.4 -3.9
Blood clot in the leg (DVT) 0.0 0.0 0.0 0.1 0.1
Medication: Paracetamol 1.7 2.9 3.3 -1.8 1.6
Headache pain in last month 1.1 2.0 3.3 0.8 -1.8
Medication for cholesterol, blood pressure or diabetes 0.4 0.7 1.3 1.1 0.3
Glaucoma (self-reported) 1.3 1.5 2.8 0.4 -1.7
Gout (self-reported) 1.2 1.6 2.5 1.6 -0.8
Hypothyroidism/myxoedema (self-reported) 1.2 2.4 2.4 1.6 -1.5
Medication: Amlodipine 0.1 0.1 0.2 0.1 -0.5
Medication: Ventolin 100micrograms inhaler 0.1 0.1 0.2 -0.0 -0.5
Birth weight 0.2 0.4 0.8 -0.9 -0.1
Chronic bronchitis/emphysema (mother) 0.6 0.8 1.2 -0.6 1.1
High blood pressure (siblings) 0.4 0.5 1.0 -1.0 0.2
Forced vital capacity (FVC), Best measure 0.2 0.8 1.4 -0.4 1.2
Body fat percentage 0.0 0.2 0.3 -0.1 -0.5
Leg fat percentage (right) 0.0 0.1 0.2 -0.1 -0.5
Arm fat-free mass (right) 1.3 6.4 11.5 3.4 -1.2
Exposure to tobacco smoke outside home 1.3 1.8 2.7 1.6 0.9
Comparative body size at age 10 2.7 7.4 8.2 2.9 -2.5
Number of full brothers 0.6 0.7 0.8 0.9 -0.8
Worry too long after embarrassment 2.1 3.6 4.9 1.5 -2.2
Seen a psychiatrist for nerves, anxiety, tension or depression 6.0 7.8 12.5 -3.5 1.8
Wheeze or whistling in the chest in last year 0.6 1.0 1.9 0.3 -1.4
Number of children fathered 1.1 1.2 1.9 -0.7 -1.4
Reason for reducing amount of alcohol drunk: Health precaution 0.8 1.0 1.8 1.3 -0.4
Age at first live birth 1.5 2.7 3.5 1.9 -1.4
Pulse wave peak to peak time 0.3 0.3 0.6 0.3 0.8
Health satisfaction 0.1 0.2 0.3 -0.6 0.2
Shortness of breath walking on level ground 0.2 0.2 0.5 0.1 0.7
Qualifications: College or University degree 0.5 1.4 2.6 0.5 -1.6
Eye problems/disorders: None of the above 1.0 1.1 1.8 -0.7 1.3
Mouth/teeth dental problems: Loose teeth 0.2 0.2 0.4 0.0 -0.6
Emphysema/chronic bronchitis 0.0 0.0 0.0 0.0 -0.0
Medication for pain relief, constipation, heartburn 0.3 0.4 0.7 0.8 -0.5
Neck or shoulder pain in last month 0.8 1.1 2.2 0.3 -1.5
Medication: Blood pressure 0.1 0.2 0.4 -0.6 0.2
Angina (self-reported) 1.3 1.8 3.0 -1.7 0.7
Migraine (self-reported) 0.1 0.1 0.1 -0.3 -0.3
Medication: Ibuprofen 0.9 1.0 2.0 0.4 -1.4
Medication: Allopurinol 0.2 0.3 0.4 0.7 -0.4
Medication: Omeprazole 2.7 3.2 4.4 1.4 -2.1
Medication: Seretide 50 evohaler 4.9 5.7 9.5 -3.1 1.4
Mean time to correctly identify matches 0.8 1.4 2.8 1.7 -0.4
Heart disease (mother) 0.3 0.4 0.5 0.5 -0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.2 1.4 1.6 -1.2 1.2
Whole body fat mass 0.3 1.4 1.7 1.3 -1.0
Leg fat mass (right) 0.3 1.0 1.2 1.1 -0.9
Arm predicted mass (right) 1.4 7.1 13.0 3.6 -1.1
Pulse rate, automated reading 1.3 4.3 5.0 2.2 -1.9
Alcohol intake frequency. 1.8 4.2 5.8 -2.4 1.6
Comparative height size at age 10 1.4 7.6 11.8 3.4 -1.9
Number of full sisters 0.3 0.4 0.6 -0.4 0.8
Suffer from ‘nerves’ 0.2 0.4 0.6 0.8 -0.4
Overall health rating 0.8 1.8 3.1 -1.8 0.7
Chest pain or discomfort 0.2 0.3 0.5 -0.2 -0.7
Had major operations 2.8 3.3 4.2 -2.0 1.5
Age at last live birth 1.3 1.9 2.4 1.2 -1.5
Family relationship satisfaction 0.0 0.0 0.0 0.1 -0.2
Leg pain on walking 1.3 1.7 2.5 -0.9 1.6
Qualifications: NVQ or HND or HNC or equivalent 2.4 2.9 4.0 2.0 -1.4
Commuting to job workplace: Car/motor vehicle 0.3 0.4 0.4 -0.6 0.6
Illness, injury, bereavement, stress in last 2 years 4.4 5.3 5.4 2.3 -2.3
Medication: Aspirin 1.0 1.3 1.6 -1.3 1.0
Supplements: Vitamin C 1.0 1.2 2.3 -1.5 0.2
Knee pain experienced in last month 0.6 0.9 1.1 -0.9 -1.1
Hypertension (Self-reported) 0.7 1.8 3.3 -1.8 -0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.1 0.1 0.3 -0.5 -0.2
Illnesses of father: Heart disease 0.6 0.8 1.4 0.4 -1.2
Illnesses of siblings: Diabetes 3.8 4.7 8.5 -2.9 1.0
Smoking status: Previous 0.0 0.0 0.0 0.1 -0.2
Forced expiratory volume in 1-second (FEV1), predicted 3.4 7.0 10.5 3.2 -1.9
Whole body fat-free mass 2.0 11.3 19.8 4.5 -1.7
Leg fat-free mass (right) 1.5 7.8 13.4 3.7 -1.5
Arm fat percentage (left) 0.0 0.1 0.2 0.1 -0.4
Average weekly red wine intake 0.0 0.0 0.0 -0.2 -0.0
Handedness (chirality/laterality): Left-handed 0.1 0.1 0.2 0.4 -0.2
Mood swings 0.0 0.1 0.1 -0.1 -0.4
Loneliness, isolation 5.5 7.6 8.1 -2.7 2.9
Long-standing illness, disability or infirmity 0.6 0.9 1.7 -1.3 -0.0
Ever had bowel cancer screening 0.6 0.7 1.4 0.0 -1.2
Diabetes diagnosed by doctor 4.8 7.8 9.5 -3.1 2.5
Ever had stillbirth, spontaneous miscarriage or termination 0.5 0.5 0.7 -0.6 0.8
Friendships satisfaction 0.0 0.0 0.0 -0.0 0.0
Qualifications: nursing, teaching 0.0 0.1 0.1 0.2 -0.2
Commuting to job workplace: Walk 0.2 0.3 0.5 0.1 0.7
Eye problems/disorders: Cataract 0.2 0.2 0.2 -0.5 0.3
Mouth/teeth dental problems: Mouth ulcers 0.7 1.2 1.8 0.7 -1.3
Medication for cholesterol 1.8 2.8 5.2 2.3 -0.7
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.9 1.0 1.3 1.1 -0.9
Back pain experienced in last month 0.7 1.0 2.0 -1.4 -0.0
Mineral and other dietary supplements 0.6 0.8 0.9 1.0 0.8
Breast cancer (self-reported) 8.1 9.7 10.9 2.9 -3.3
Asthma (self-reported) 1.5 2.9 3.3 -1.6 1.8
Osteoporosis (self-reported) 0.4 0.5 1.0 -0.3 -1.0
Osteoarthritis (self-reported) 0.8 1.0 1.0 -1.0 1.0
Medication: Aspirin 1.4 1.9 2.3 -1.5 1.2
Medication: Gliclazide 0.4 0.4 0.7 -0.8 0.4
Illnesses of father: None of the above (group 1) 0.9 1.2 2.3 -0.3 1.5
Smoking status: Current 0.1 0.1 0.2 0.5 -0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.6 3.5 5.9 -1.0 2.4
Whole body water mass 1.9 11.1 19.7 4.4 -1.6
Leg predicted mass (right) 1.5 8.0 13.5 3.7 -1.6
Arm fat mass (left) 0.3 1.2 1.7 1.3 -0.8
Number of self-reported non-cancer illnesses 1.2 2.1 4.1 -2.0 -0.3
Average weekly champagne plus white wine intake 1.5 2.0 2.7 1.6 -1.1
Miserableness 0.2 0.3 0.5 0.4 -0.7
Guilty feelings 5.1 7.7 9.4 3.1 -2.5
Wears glasses or contact lenses 0.9 1.0 2.0 1.4 0.3
Ever taken oral contraceptive pill 6.5 7.3 10.2 -3.2 2.1
Hearing aid user 0.7 0.7 1.2 -0.5 1.1
Mother’s age at death 0.2 0.2 0.3 -0.6 0.3
Financial situation satisfaction 1.0 1.3 2.1 -1.4 0.7
Tinnitus: Yes, now most or all of the time 3.1 3.6 5.3 -2.3 1.4
Commuting to job workplace: Public transport 0.3 0.3 0.6 0.0 0.8
Eye problems/disorders: Glaucoma 0.8 1.0 1.8 -0.5 -1.3
Medication: Blood pressure 0.7 1.3 1.7 -0.9 -1.3
Pain type(s) experienced in last month: Hip pain 3.6 4.5 7.9 -2.8 1.1
Supplements: Fish oil (including cod liver oil) 0.6 0.8 1.4 -1.2 -0.6
High cholesterol (Self-reported) 0.6 1.0 1.3 -1.1 0.8
Medication: Bendroflumethiazide 0.7 1.0 1.1 -1.0 1.0
Medication: Paracetamol 2.5 3.9 4.6 -2.1 1.8
Medication: Lisinopril 0.3 0.4 0.6 0.5 -0.8
Medication: Atorvastatin 0.0 0.0 0.0 0.0 0.0
Illnesses of father: High blood pressure 0.5 0.6 1.1 -0.1 -1.1
Alcohol drinker status: Never 0.9 1.1 1.3 0.9 -1.1
Ever smoked 0.9 1.6 2.0 1.1 -1.4
Basal metabolic rate 1.7 9.6 16.7 4.1 -1.6
Leg fat percentage (left) 0.0 0.1 0.2 -0.4 -0.4
Arm fat-free mass (left) 1.6 8.0 13.7 3.7 -1.5
Number of operations (self-reported) 2.8 4.2 7.9 -2.8 0.7
Average weekly beer plus cider intake 0.3 0.4 0.8 0.9 -0.1
Irritability 0.1 0.1 0.2 -0.5 -0.2
Risk taking 2.5 3.7 6.8 -2.6 -0.8
Ever had prostate specific antigen (PSA) test 0.1 0.2 0.2 0.4 -0.4
Fractured/broken bones in last 5 years 1.2 1.6 2.1 1.0 -1.5
Age started oral contraceptive pill 0.9 1.1 1.8 -0.6 1.3
Diastolic blood pressure, automated reading 0.5 1.6 3.1 -0.3 -1.8
Ever depressed for a whole week 5.2 6.5 10.5 -3.2 1.6
Unable to work because of sickness or disability 0.3 0.4 0.6 -0.5 0.8
Commuting to job workplace: Cycle 0.7 0.8 1.5 -0.4 1.2
Myopia 1.8 2.5 4.9 -0.4 2.2
Vascular/heart problems diagnosed by doctor 0.7 1.9 3.5 1.9 0.6
Cholesterol lowering medication 0.1 0.1 0.2 -0.0 -0.4
Medication: Omeprazole (e.g. Zanprol) 1.9 2.3 3.7 1.0 -1.9
Pain experienced in last month 0.7 1.1 1.4 0.9 1.2
Supplements: Calcium 0.2 0.3 0.5 -0.7 0.3
Basal cell carcinoma (self-reported) 2.6 3.1 3.5 1.9 -1.7
Heart attack/myocardial infarction (self-reported) 0.3 0.3 0.4 -0.6 -0.6
Deep venous thrombosis (DVT) (self-reported) 0.2 0.2 0.4 -0.3 0.6
Heart disease (siblings) 0.7 0.8 0.9 -0.9 -0.9
Alcohol drinker status: Previous 5.0 5.7 5.7 -2.4 2.4
Pack years of smoking 0.4 0.6 1.1 0.3 -1.1
Impedance of whole body 0.2 1.1 2.0 -1.4 0.4
Leg fat mass (left) 0.2 0.6 0.8 0.9 -0.7
Arm predicted mass (left) 1.6 8.0 14.1 3.8 -1.4