[Hub]/) : Traits : Heel T-Score : ← →

chr11:7,714,238-10,033,265

Best TWAS P=4.3e-30 · Best GWAS P=5.27e-36 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ST5	0.10	0.08	lasso	4	0.09	8.6e-11	-7.5	6.7	2.1e-11	-0.48	1.00	0.00	FALSE
2	GTEx	Adipose Subcutaneous	AKIP1	0.08	0.08	lasso	5	0.09	8.1e-08	5.4	7.4	1.6e-13	-0.30	0.99	0.01	FALSE
3	GTEx	Adipose Subcutaneous	TMEM9B	0.16	0.04	lasso	6	0.07	2.4e-06	2.1	6.1	9.3e-10	-0.53	0.59	0.16	FALSE
4	GTEx	Adipose Subcutaneous	TMEM9B-AS1	0.55	0.42	enet	33	0.49	5.7e-45	-9.3	-8.7	3.4e-18	0.56	1.00	0.00	FALSE
5	GTEx	Adipose Visceral Omentum	TMEM9B-AS1	0.41	0.30	enet	8	0.36	2.1e-19	-9.4	-9.8	1.0e-22	0.66	1.00	0.00	FALSE
6	GTEx	Adrenal Gland	TMEM9B-AS1	0.50	0.22	enet	23	0.38	1.3e-14	-11.3	-9.4	6.4e-21	0.60	0.75	0.25	FALSE
7	GTEx	Artery Aorta	TMEM9B-AS1	0.35	0.33	lasso	5	0.31	1.2e-17	-9.3	-9.8	1.4e-22	0.67	1.00	0.00	FALSE
8	GTEx	Artery Coronary	TMEM9B-AS1	0.41	0.32	lasso	3	0.37	2.7e-13	-9.3	-8.8	2.0e-18	0.58	0.99	0.00	FALSE
9	GTEx	Artery Tibial	AKIP1	0.12	0.07	enet	32	0.09	1.0e-07	-9.6	7.5	7.4e-14	-0.49	0.93	0.04	TRUE
10	GTEx	Artery Tibial	TMEM9B-AS1	0.63	0.28	enet	70	0.37	9.2e-31	-11.3	-6.6	5.4e-11	0.50	1.00	0.00	FALSE
11	GTEx	Brain Caudate basal ganglia	TMEM9B-AS1	0.45	0.22	enet	22	0.34	1.7e-10	-9.4	-6.8	1.1e-11	0.48	0.89	0.02	FALSE
12	GTEx	Brain Cerebellar Hemisphere	TMEM9B-AS1	0.60	0.35	lasso	9	0.38	1.3e-10	-11.3	-11.3	1.1e-29	0.80	0.69	0.30	FALSE
13	GTEx	Brain Cerebellum	AKIP1	0.15	0.03	lasso	7	0.03	5.9e-02	7.3	6.5	6.6e-11	-0.37	0.12	0.11	FALSE
14	GTEx	Brain Cerebellum	TMEM9B-AS1	0.51	0.41	lasso	7	0.38	3.2e-12	-9.4	-10.5	1.2e-25	0.68	0.84	0.16	FALSE
15	GTEx	Brain Cortex	TMEM9B-AS1	0.19	-0.01	lasso	6	0.02	1.0e-01	-11.3	-10.6	2.5e-26	0.72	0.04	0.69	TRUE
16	GTEx	Brain Frontal Cortex BA9	TMEM9B-AS1	0.48	0.20	lasso	6	0.26	1.2e-07	4.6	-8.3	1.5e-16	0.54	0.34	0.12	FALSE
17	GTEx	Brain Hippocampus	TMEM9B-AS1	0.35	0.27	enet	15	0.26	6.2e-07	-9.4	-8.3	1.1e-16	0.56	0.17	0.24	FALSE
18	GTEx	Brain Nucleus accumbens basal ganglia	TMEM9B-AS1	0.40	0.16	enet	3	0.18	1.5e-05	-11.3	-10.6	2.5e-26	0.75	0.18	0.44	FALSE
19	GTEx	Brain Putamen basal ganglia	TMEM9B-AS1	0.49	0.37	lasso	7	0.35	2.8e-09	-9.4	-9.6	6.4e-22	0.67	0.65	0.18	FALSE
20	GTEx	Breast Mammary Tissue	TMEM9B-AS1	0.63	0.40	lasso	8	0.40	4.7e-22	-9.3	-10.0	1.7e-23	0.68	1.00	0.00	FALSE
21	GTEx	Breast Mammary Tissue (Male)	AKIP1	0.19	-0.01	lasso	3	-0.01	7.0e-01	6.9	6.8	7.4e-12	-0.37	0.04	0.11	FALSE
22	GTEx	Breast Mammary Tissue (Male)	TMEM9B-AS1	0.31	0.27	lasso	2	0.21	1.2e-05	-9.4	-9.4	7.9e-21	0.66	0.22	0.09	FALSE
23	GTEx	Cells EBV-transformed lymphocytes	TMEM9B-AS1	0.70	0.29	lasso	5	0.39	7.1e-14	4.6	-8.6	1.2e-17	0.55	0.57	0.42	FALSE
24	GTEx	Cells Transformed fibroblasts	AKIP1	0.12	0.09	enet	18	0.10	4.4e-08	7.4	10.3	5.0e-25	-0.62	0.76	0.23	FALSE
25	GTEx	Cells Transformed fibroblasts	TMEM41B	0.14	0.00	enet	23	0.03	5.1e-03	-3.5	5.7	1.0e-08	-0.37	0.11	0.23	FALSE
26	GTEx	Cells Transformed fibroblasts	TMEM9B	0.13	0.04	enet	16	0.06	2.7e-05	-8.1	5.5	3.0e-08	-0.48	0.50	0.09	FALSE
27	GTEx	Cells Transformed fibroblasts	TMEM9B-AS1	0.47	0.30	enet	24	0.36	9.0e-28	-9.4	-8.8	8.8e-19	0.58	1.00	0.00	FALSE
28	GTEx	Colon Sigmoid	TMEM9B-AS1	0.36	0.24	lasso	3	0.27	4.0e-10	-9.4	-10.4	1.6e-25	0.71	0.94	0.06	FALSE
29	GTEx	Colon Transverse	TMEM9B-AS1	0.52	0.39	lasso	5	0.38	5.1e-19	-9.4	-9.3	1.8e-20	0.62	1.00	0.00	FALSE
30	GTEx	Esophagus Gastroesophageal Junction	TMEM9B-AS1	0.58	0.41	enet	16	0.37	1.6e-14	-9.3	-9.8	8.8e-23	0.68	0.99	0.01	FALSE
31	GTEx	Esophagus Mucosa	TMEM9B-AS1	0.67	0.42	lasso	7	0.48	5.5e-36	-9.3	-9.6	1.3e-21	0.66	1.00	0.00	TRUE
32	GTEx	Esophagus Muscularis	AKIP1	0.21	0.01	enet	25	0.07	2.6e-05	-9.6	8.7	4.1e-18	-0.52	0.15	0.46	FALSE
33	GTEx	Esophagus Muscularis	TMEM9B-AS1	0.66	0.50	lasso	3	0.49	1.4e-33	-9.4	-9.7	2.1e-22	0.67	1.00	0.00	FALSE
34	GTEx	Heart Atrial Appendage	TMEM9B-AS1	0.74	0.41	enet	23	0.46	4.4e-23	-9.4	-9.6	1.3e-21	0.68	1.00	0.00	FALSE
35	GTEx	Heart Left Ventricle	SCUBE2	0.17	0.06	lasso	8	0.12	5.2e-07	3.7	7.5	5.2e-14	-0.53	0.63	0.32	TRUE
36	GTEx	Heart Left Ventricle	TMEM9B-AS1	0.33	0.34	lasso	4	0.33	2.6e-18	-9.3	-9.9	4.9e-23	0.67	1.00	0.00	FALSE
37	GTEx	Liver	TMEM9B-AS1	0.24	0.05	enet	12	0.01	1.3e-01	-9.3	-8.7	3.1e-18	0.56	0.14	0.24	FALSE
38	GTEx	Lung	AKIP1	0.11	0.06	lasso	7	0.09	2.0e-07	6.4	7.7	1.2e-14	-0.46	0.96	0.02	TRUE
39	GTEx	Lung	TMEM9B-AS1	0.54	0.46	enet	8	0.48	1.4e-41	-9.3	-9.8	1.6e-22	0.66	1.00	0.00	FALSE
40	GTEx	Muscle Skeletal	TMEM9B-AS1	0.78	0.52	enet	57	0.58	3.6e-69	-9.3	-8.6	9.8e-18	0.56	1.00	0.00	FALSE
41	GTEx	Nerve Tibial	AKIP1	0.16	0.07	lasso	6	0.08	2.7e-06	7.2	6.9	7.0e-12	-0.32	0.99	0.00	FALSE
42	GTEx	Nerve Tibial	TMEM9B-AS1	0.74	0.44	enet	22	0.54	1.8e-44	-9.3	-9.8	1.5e-22	0.68	1.00	0.00	FALSE
43	GTEx	Ovary	TMEM9B-AS1	0.65	0.38	lasso	5	0.39	1.3e-10	-9.4	-10.3	4.5e-25	0.71	0.74	0.22	FALSE
44	GTEx	Pancreas	TMEM9B	0.13	0.00	lasso	6	0.00	5.9e-01	-5.1	-8.4	2.8e-17	0.50	0.06	0.27	FALSE
45	GTEx	Pancreas	TMEM9B-AS1	0.32	0.28	enet	7	0.31	1.1e-13	-9.3	-10.2	1.8e-24	0.71	0.99	0.01	FALSE
46	GTEx	Pituitary	AKIP1	0.17	0.07	lasso	5	0.02	8.6e-02	8.5	7.9	3.3e-15	-0.40	0.08	0.07	FALSE
47	GTEx	Pituitary	TMEM9B-AS1	0.57	0.42	lasso	6	0.40	5.5e-11	-11.3	-11.0	2.6e-28	0.77	0.62	0.37	FALSE
48	GTEx	Prostate	TMEM9B-AS1	0.54	0.33	lasso	2	0.37	3.9e-10	-9.4	-9.0	3.3e-19	0.60	0.42	0.56	FALSE
49	GTEx	Skin Not Sun Exposed Suprapubic	TMEM9B-AS1	0.50	0.41	lasso	4	0.49	1.8e-30	-11.3	-10.6	2.5e-26	0.76	1.00	0.00	FALSE
50	GTEx	Skin Sun Exposed Lower leg	AKIP1	0.05	0.05	enet	8	0.04	1.7e-04	8.3	9.7	2.0e-22	-0.62	0.10	0.83	FALSE
51	GTEx	Skin Sun Exposed Lower leg	SCUBE2	0.12	0.01	enet	8	0.01	1.1e-01	-5.1	-6.5	9.9e-11	0.17	0.10	0.08	TRUE
52	GTEx	Skin Sun Exposed Lower leg	TMEM9B-AS1	0.65	0.49	enet	14	0.55	1.7e-53	-9.3	-10.0	2.2e-23	0.70	1.00	0.00	FALSE
53	GTEx	Small Intestine Terminal Ileum	AKIP1	0.23	0.20	enet	11	0.12	1.4e-03	6.4	6.2	4.8e-10	-0.37	0.40	0.16	FALSE
54	GTEx	Spleen	TMEM9B-AS1	0.37	0.21	lasso	5	0.22	3.1e-06	-11.3	-11.4	4.3e-30	0.79	0.01	0.95	TRUE
55	GTEx	Stomach	TMEM9B-AS1	0.56	0.38	lasso	5	0.42	2.0e-21	-9.4	-9.2	3.8e-20	0.63	1.00	0.00	FALSE
56	GTEx	Testis	AKIP1	0.19	0.05	enet	22	0.11	1.7e-05	3.1	5.1	2.7e-07	-0.46	0.87	0.04	FALSE
57	GTEx	Testis	TMEM9B-AS1	0.57	0.46	lasso	3	0.50	7.7e-25	-9.3	-10.1	4.2e-24	0.72	1.00	0.00	FALSE
58	GTEx	Thyroid	AKIP1	0.16	0.23	lasso	7	0.21	2.6e-16	7.3	7.0	2.3e-12	-0.35	1.00	0.00	FALSE
59	GTEx	Thyroid	TMEM9B-AS1	0.59	0.43	enet	12	0.45	5.3e-38	-9.3	-9.9	4.1e-23	0.67	1.00	0.00	FALSE
60	GTEx	Uterus	TMEM9B-AS1	0.37	0.43	lasso	3	0.42	1.4e-09	-9.4	-9.4	8.3e-21	0.65	0.46	0.18	FALSE
61	GTEx	Vagina	TMEM9B-AS1	0.63	0.44	lasso	12	0.38	1.6e-09	-9.4	-9.2	3.3e-20	0.64	0.80	0.12	FALSE
62	GTEx	Whole Blood	RP11-152H18.3	0.04	0.02	lasso	4	0.01	2.0e-02	7.5	7.3	2.1e-13	-0.38	0.67	0.05	FALSE
63	GTEx	Whole Blood	TMEM9B-AS1	0.22	0.14	lasso	3	0.13	3.3e-12	-9.4	-9.7	2.0e-22	0.69	1.00	0.00	FALSE
64	NTR	Blood	TMEM9B	0.04	0.01	enet	16	0.03	2.6e-10	-9.3	-7.9	2.6e-15	0.49	0.95	0.04	FALSE
65	ROSMAP	Brain Pre-frontal Cortex	STK33	0.10	0.04	bslmm	632	0.07	1.5e-09	1.6	-5.6	2.5e-08	0.24	0.88	0.04	FALSE
66	ROSMAP	Brain Pre-frontal Cortex	ST5	0.08	0.06	lasso	5	0.06	4.4e-08	-7.5	8.7	2.6e-18	-0.59	0.94	0.06	FALSE
67	ROSMAP	Brain Pre-frontal Cortex	TMEM9B	0.18	0.06	enet	25	0.13	9.6e-17	-10.0	6.5	9.3e-11	-0.43	1.00	0.00	FALSE
68	ROSMAP	Brain Pre-frontal Cortex	TMEM9B-AS1	0.29	0.24	lasso	4	0.24	2.5e-30	-9.4	-10.0	2.3e-23	0.66	1.00	0.00	FALSE
69	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	C11orf17	0.04	0.01	enet	4	0.05	3.3e-05	-12.5	7.6	3.3e-14	-0.73	0.01	0.84	FALSE
70	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C11orf17	0.35	0.05	enet	23	0.07	3.9e-08	-12.5	7.7	1.4e-14	-0.62	0.00	1.00	FALSE
71	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ST5	0.03	0.05	lasso	3	0.04	8.0e-06	7.4	7.5	4.9e-14	-0.40	0.60	0.22	FALSE
72	The Cancer Genome Atlas	Brain Lower Grade Glioma	C11orf17	0.10	0.03	lasso	2	0.05	9.2e-07	2.0	7.7	1.4e-14	-0.72	0.03	0.96	FALSE
73	The Cancer Genome Atlas	Brain Lower Grade Glioma	TMEM9B	0.09	0.03	blup	52	0.04	6.8e-05	2.0	5.6	2.5e-08	-0.53	0.14	0.30	FALSE
74	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	C11orf17	0.03	0.02	lasso	2	0.02	3.4e-03	7.2	7.4	1.4e-13	-0.39	0.04	0.18	FALSE
75	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	TMEM9B	0.06	0.00	blup	52	0.00	8.0e-02	-11.0	10.2	2.1e-24	-0.72	0.01	0.40	FALSE
76	The Cancer Genome Atlas	Stomach Adenocarcinoma	TMEM9B	0.11	0.00	blup	52	0.01	6.0e-02	-10.0	9.1	9.7e-20	-0.76	0.01	0.65	FALSE
77	The Cancer Genome Atlas	Thyroid Carcinoma	TMEM9B	0.45	0.07	blup	52	0.12	4.2e-12	-11.0	9.9	6.3e-23	-0.71	0.01	0.99	FALSE