TWAS hub - SCUBE2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0530	0.0240	9.8e-04	0.005	0.020	0.034	0.022	0.014	6.7e-02	1.4e-03	4.5e-05	8.8e-04	6.3e-03
2	GTEx	Adipose Subcutaneous	0.3130	0.0640	2.9e-14	0.273	NA	0.244	NA	0.257	2.2e-22	NA	6.8e-20	NA	5.5e-21
3	GTEx	Adipose Visceral Omentum	0.0890	0.0470	6.9e-03	0.145	NA	0.118	NA	0.147	6.1e-08	NA	1.1e-06	NA	4.5e-08
4	GTEx	Artery Tibial	0.0962	0.0422	3.7e-03	-0.003	NA	0.009	NA	-0.001	7.2e-01	NA	5.8e-02	NA	4.0e-01
5	GTEx	Brain Cerebellar Hemisphere	0.3730	0.1110	2.2e-04	0.187	NA	0.184	NA	0.140	1.5e-05	NA	1.9e-05	NA	2.0e-04
6	GTEx	Brain Cerebellum	0.2270	0.0880	1.1e-03	-0.009	NA	0.031	NA	0.002	7.9e-01	NA	4.3e-02	NA	2.8e-01
7	GTEx	Esophagus Mucosa	0.1270	0.0500	1.6e-03	0.004	NA	-0.001	NA	0.003	1.6e-01	NA	4.0e-01	NA	1.8e-01
8	GTEx	Esophagus Muscularis	0.1160	0.0430	1.4e-04	0.132	NA	0.115	NA	0.119	2.1e-08	NA	1.9e-07	NA	1.0e-07
9	GTEx	Heart Atrial Appendage	0.3920	0.0920	8.7e-08	0.298	NA	0.267	NA	0.289	7.0e-14	NA	2.2e-12	NA	2.0e-13
10	GTEx	Heart Left Ventricle	0.1673	0.0537	5.3e-05	0.063	NA	0.116	NA	0.122	2.9e-04	NA	9.9e-07	NA	5.2e-07
11	GTEx	Lung	0.1751	0.0733	1.8e-03	0.020	NA	0.051	NA	0.028	1.1e-02	NA	9.2e-05	NA	3.2e-03
12	GTEx	Nerve Tibial	0.2297	0.0622	2.0e-06	0.110	NA	0.140	NA	0.135	3.7e-08	NA	4.1e-10	NA	8.0e-10
13	GTEx	Pancreas	0.2520	0.0730	1.2e-05	0.245	NA	0.246	NA	0.272	9.5e-11	NA	9.2e-11	NA	6.2e-12
14	GTEx	Skin Sun Exposed Lower leg	0.1190	0.0450	1.1e-03	0.006	NA	0.005	NA	0.003	9.7e-02	NA	1.1e-01	NA	1.7e-01
15	GTEx	Testis	0.2670	0.0750	4.8e-06	0.273	NA	0.252	NA	0.020	1.6e-12	NA	1.4e-11	NA	4.2e-02
16	GTEx	Thyroid	0.1670	0.0600	7.6e-05	0.023	NA	0.034	NA	0.044	7.0e-03	NA	1.3e-03	NA	2.4e-04
17	METSIM	Adipose	0.2126	0.0463	0.0e+00	0.231	0.179	0.221	0.229	0.226	5.4e-34	5.7e-26	2.2e-32	1.2e-33	3.5e-33
18	TCGA	Esophageal Carcinoma	0.1750	0.0920	1.8e-03	0.036	0.087	0.076	NA	0.082	2.6e-02	1.0e-03	2.1e-03	NA	1.4e-03
19	TCGA	Kidney Renal Clear Cell Carcinoma	0.0575	0.0246	9.4e-05	0.026	0.029	0.024	NA	0.021	5.5e-04	3.0e-04	9.3e-04	NA	1.9e-03
20	TCGA	Brain Lower Grade Glioma	0.0881	0.0326	1.5e-05	0.027	0.043	0.022	NA	0.023	4.2e-04	1.1e-05	1.4e-03	NA	1.1e-03
21	TCGA	Prostate Adenocarcinoma	0.1742	0.0893	9.7e-04	0.078	0.050	0.057	NA	0.074	1.6e-08	5.1e-06	1.2e-06	NA	3.6e-08
22	TCGA	Rectum Adenocarcinoma	0.1590	0.0830	5.4e-03	0.049	0.064	0.044	NA	0.029	2.7e-02	1.3e-02	3.5e-02	NA	7.0e-02
23	TCGA	Thyroid Carcinoma	0.1190	0.0450	7.3e-07	0.068	0.062	0.065	NA	0.068	3.4e-07	1.2e-06	5.8e-07	NA	3.5e-07

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23
Eye problems/disorders: None of the above	4.2	4.8	11.4	1.2	3.0	2.6	1.0	1.6	1.7	2.6	2.8	2.3	1.1	3.1	-1.3	3.4	0.1	3.1	2.8	0.8	3.3	1.7	0.3	3.2	-0.4
Worry too long after embarrassment	4.0	6.8	17.2	-2.4	-3.7	-3.4	-3.5	-1.3	1.6	-3.4	-3.2	-1.9	-2.3	-2.7	2.0	-0.9	0.1	-4.0	-3.8	-2.7	-1.9	-2.5	-0.6	-4.1	0.4
Medication: Gliclazide	3.9	4.4	10.4	-0.2	-3.0	-3.0	-2.0	0.7	-0.5	-3.1	-3.2	-2.9	0.0	-2.8	1.1	-1.5	1.2	-2.8	-3.1	-1.0	-2.7	1.0	-1.8	-2.3	1.6
Had major operations	3.6	4.3	10.8	-2.1	-2.8	-2.4	-2.4	-0.7	-0.5	-2.5	-2.2	-2.3	-1.4	-3.1	0.3	-3.3	-0.2	-3.2	-2.5	-0.0	-3.1	-1.3	-0.7	-2.4	0.2
Taking other prescription medications	3.4	5.3	10.2	-2.2	-2.9	-3.0	-3.1	-1.4	1.2	-2.9	-2.8	-3.1	-0.8	-3.2	-1.5	0.1	-2.6	-2.5	-3.0	0.3	-1.9	-2.8	2.4	-1.3	-2.2
Medication: Ventolin 100micrograms inhaler	3.4	4.3	10.0	-0.9	-3.1	-3.0	-2.3	-1.1	-0.1	-3.0	-3.1	-3.1	-1.4	-2.9	1.6	-1.4	0.4	-2.8	-3.2	-1.0	-2.8	-0.1	-0.7	-1.9	0.3
Diabetes diagnosed by doctor	3.3	5.4	14.2	-1.3	-3.6	-3.4	-2.1	-0.3	0.5	-3.5	-3.7	-3.4	-0.5	-3.8	-0.1	-1.4	0.2	-3.4	-3.5	-0.6	-3.0	-0.7	-0.7	-2.4	0.8
Reaction Time	3.1	5.9	18.6	-2.3	-3.3	-3.2	-3.4	1.3	1.3	-3.3	-2.9	-2.9	-1.5	-4.3	-1.2	-2.5	-0.6	-3.4	-3.3	0.2	-3.1	-1.1	0.8	-2.0	-0.0
Allergy or Eczema	3.1	8.2	19.5	-0.6	-4.4	-3.9	-1.6	-1.3	-1.0	-4.0	-3.9	-3.0	-1.2	-3.2	2.4	-2.9	0.6	-4.0	-4.0	-3.4	-3.5	-1.2	-1.3	-4.4	1.7
Lung FEV1/FVC ratio	3.1	15.8	42.1	2.3	4.9	4.8	6.2	1.4	-4.1	4.8	4.1	6.5	3.3	6.5	-2.4	0.2	1.6	6.5	5.1	-0.3	3.9	3.1	-0.2	3.4	2.8
Forced expiratory volume in 1-second (FEV1), Best measure	3.1	10.0	32.6	0.9	4.7	4.9	3.8	0.2	-0.9	4.8	4.9	4.8	0.7	5.7	-2.0	1.3	-0.1	4.5	5.0	-0.0	3.0	0.5	0.6	1.5	0.2
Mean time to correctly identify matches	3.1	5.9	19.3	-2.7	-3.3	-3.2	-3.4	1.1	0.7	-3.2	-2.9	-2.6	-1.1	-4.4	-1.4	-3.0	-1.1	-3.2	-3.2	0.5	-2.8	-1.7	1.1	-1.8	-0.4
Worry (Nagel 2018)	2.8	5.8	15.3	-2.3	-3.6	-3.4	-2.9	-2.3	0.5	-3.4	-3.0	-1.8	-1.9	-2.1	0.9	-1.6	-0.6	-3.1	-3.5	-2.5	-2.2	-2.4	0.7	-3.9	-0.2
Waist Hip Ratio (WHR)	2.8	12.8	29.3	-3.5	-5.0	-4.3	-4.8	-1.3	0.6	-4.4	-4.6	-3.0	-3.7	-4.3	0.3	-4.3	0.8	-4.8	-4.7	-2.6	-4.3	-2.2	-2.6	-5.4	0.9
Medication: Ramipril	2.8	3.6	11.1	1.9	2.3	2.0	1.1	1.1	1.8	2.0	2.0	1.9	1.9	2.3	-1.0	3.3	-0.4	2.8	1.9	0.5	3.3	0.4	1.0	2.6	-1.0
Emphysema/chronic bronchitis	2.8	3.1	7.9	-1.7	-1.7	-1.6	-2.8	-2.4	1.4	-1.6	-1.0	-1.9	-1.9	-2.2	-1.8	-1.6	-2.2	-1.5	-1.6	0.7	-1.7	-1.9	2.3	-1.1	-1.8
Type 2 Diabetes (T2D) (2018)	2.7	5.1	14.5	-1.8	-3.4	-3.3	-2.4	-0.8	0.4	-3.4	-3.6	-3.3	-1.0	-3.8	-0.4	-0.6	-0.5	-3.0	-3.5	-0.2	-2.5	-0.6	-0.5	-2.1	-0.6
Respiratory disease	2.6	5.8	15.2	-2.2	-3.3	-3.1	-2.5	-1.2	0.5	-3.1	-2.7	-3.9	-0.7	-3.8	0.8	-2.1	-0.8	-3.9	-3.2	-0.2	-3.5	-1.9	0.2	-2.4	-0.7
Allergy	2.6	6.1	13.9	1.1	3.7	3.3	2.0	2.3	0.2	3.4	3.3	3.0	1.7	3.1	-0.8	2.0	0.7	3.4	3.4	2.0	3.3	2.1	-0.0	3.5	0.1
Diabetes (self-reported)	2.6	4.1	12.8	-1.3	-3.0	-3.0	-1.9	0.2	-0.0	-3.0	-3.4	-2.8	-0.5	-3.6	0.5	-1.0	0.3	-2.9	-3.2	0.0	-2.1	-0.4	-0.9	-1.6	0.5
Neuroticism score	2.6	5.4	12.7	-2.4	-3.5	-3.2	-2.3	-2.6	1.9	-3.1	-3.1	-1.8	-1.8	-2.0	-0.9	-0.8	-0.8	-3.0	-3.4	-2.9	-1.8	-2.1	0.9	-3.6	0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.6	3.1	6.8	1.8	2.0	2.0	1.6	2.2	-1.7	1.9	1.9	1.0	2.6	1.8	1.8	0.7	1.7	2.0	2.1	1.3	1.3	2.3	-1.9	2.1	0.9
Frequency of tenseness / restlessness in last 2 weeks	2.5	3.9	9.9	-0.0	-3.1	-3.0	-1.3	0.2	-0.0	-3.0	-3.0	-1.6	-0.6	-1.9	0.9	-1.7	1.6	-2.5	-3.1	-2.2	-1.4	0.3	-1.9	-2.5	2.4
Shortness of breath walking on level ground	2.5	2.9	7.1	-1.3	-2.6	-2.5	-1.5	-0.3	0.8	-2.5	-2.3	-2.2	-1.1	-2.0	-0.2	-1.3	-0.1	-1.9	-2.5	-1.2	-2.2	-1.7	0.0	-2.7	-0.5
Neuroticism	2.4	5.7	12.6	-2.8	-3.4	-3.1	-2.3	-2.9	1.6	-3.1	-3.0	-2.0	-2.0	-2.3	-0.6	-1.0	-1.2	-3.0	-3.4	-2.4	-1.9	-2.7	1.2	-3.5	-0.2
Illnesses of father: High blood pressure	2.4	3.0	11.2	3.3	-1.2	-1.5	0.4	2.6	0.1	-1.4	-1.5	-1.9	1.4	-1.0	0.5	0.1	3.2	-0.8	-1.4	-0.8	-1.4	3.0	-2.7	-0.1	2.2
Maternal smoking around birth	2.3	3.3	6.0	-0.8	2.3	2.2	0.8	-0.9	2.0	2.2	2.1	1.5	-1.4	1.9	-2.0	2.5	-1.9	2.3	2.1	1.6	2.3	-1.6	1.7	1.4	-2.2
Medication: Lansoprazole	2.3	2.6	6.6	-2.0	-1.8	-1.7	-2.4	-2.5	0.0	-1.6	-1.8	-1.3	-1.6	-1.3	0.3	-1.3	-1.6	-1.7	-1.9	-1.1	-1.2	-2.6	0.8	-2.1	-0.6
Hayfever, allergic rhinitis or eczema	2.2	4.7	11.8	0.2	-3.3	-3.0	-0.9	-1.4	-0.9	-3.0	-3.1	-2.3	-1.0	-2.2	1.8	-1.5	0.6	-2.9	-3.0	-3.0	-2.7	-1.0	-1.0	-3.4	1.4
Stomach or abdominal pain in last month	2.2	2.7	15.6	-1.0	-2.1	-1.8	-0.6	-0.9	1.3	-1.8	-1.8	-1.9	-0.6	-0.8	0.4	-0.5	0.4	-2.2	-2.0	-2.4	-2.2	-0.9	-1.1	-4.0	1.1
Worrier / anxious feelings	2.2	4.1	11.2	-1.1	-3.1	-3.1	-2.1	-0.7	1.5	-3.0	-2.7	-1.8	-1.0	-1.7	0.7	-0.6	-0.1	-2.6	-3.1	-2.9	-1.6	-1.9	0.4	-3.3	-0.2
Eye problems/disorders: Cataract	2.2	2.5	6.6	-0.3	-2.5	-2.5	-1.3	-0.1	-0.3	-2.4	-2.4	-2.6	-0.3	-2.2	-0.7	-1.0	-0.1	-2.2	-2.5	-0.4	-2.2	-1.2	-0.1	-1.5	0.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.2	4.6	10.8	0.1	3.0	2.9	1.7	2.8	0.6	3.0	3.1	3.1	0.0	3.1	-2.2	1.3	0.4	2.9	3.3	1.8	2.4	0.1	-0.4	2.0	-0.0
Guilty feelings	2.1	3.2	12.6	-1.3	-2.4	-2.0	-1.6	-2.4	1.9	-2.0	-1.8	-1.3	-1.4	-0.7	0.1	-0.7	0.0	-2.1	-2.3	-2.9	-1.2	-2.1	-0.1	-3.6	0.9
Tinnitus: Yes, but not now, but have in the past	2.0	2.1	4.9	-1.2	-2.2	-2.0	-1.5	0.1	-1.1	-2.0	-2.2	-1.3	-1.2	-2.1	-0.7	-1.7	0.2	-1.9	-2.0	-0.6	-1.9	-1.1	-1.0	-1.5	0.5
Peak expiratory flow (PEF)	2.0	4.7	10.8	1.1	3.1	3.2	2.0	0.5	-1.9	3.3	3.1	3.3	1.6	2.9	-1.0	-0.0	0.4	3.1	3.3	1.2	1.9	1.9	0.3	2.4	0.7
Glaucoma (self-reported)	2.0	2.3	5.9	-1.1	-2.4	-2.2	0.4	-2.4	-0.7	-2.2	-2.4	-0.8	-0.7	-1.3	1.3	-1.2	-0.0	-1.6	-2.2	-1.8	-0.7	-1.6	0.2	-2.3	0.4
Long-standing illness, disability or infirmity	2.0	3.0	5.9	-1.8	-2.2	-2.0	-2.4	-1.1	1.4	-2.1	-2.2	-2.0	-0.1	-2.4	-1.7	-0.3	-1.5	-2.1	-2.2	-0.8	-1.8	-1.9	0.9	-2.4	-0.8
Blood Platelet Count	1.9	21.9	132.2	6.3	4.7	3.3	2.4	6.8	-1.3	3.5	3.2	0.4	5.2	-0.4	0.9	4.5	3.0	3.5	3.2	9.4	4.7	5.6	-1.5	11.5	0.5
Hair/balding pattern: Pattern 2	1.9	2.4	7.3	-0.6	-1.9	-1.9	-1.6	-1.5	-1.4	-1.8	-2.1	-2.1	-0.5	-2.0	1.4	-0.6	0.1	-2.7	-2.0	-0.5	-2.1	-0.4	-0.3	-2.2	0.4
Frequency of tiredness / lethargy in last 2 weeks	1.9	3.1	7.4	-0.4	-2.6	-2.6	-2.0	-1.7	1.4	-2.6	-2.4	-2.1	-1.3	-1.9	0.5	0.0	0.2	-2.6	-2.7	-1.8	-1.6	-0.2	-0.4	-2.5	0.5
Forced expiratory volume in 1-second (FEV1)	1.9	6.6	21.2	1.4	3.8	3.8	2.7	0.6	0.1	3.8	3.9	3.6	1.4	4.6	-2.1	1.7	0.1	3.7	4.0	-0.3	2.1	1.1	0.9	1.7	0.5
Illnesses of mother	1.9	2.3	9.9	-0.5	1.9	1.6	0.8	0.4	0.5	1.7	1.5	1.1	-0.9	0.2	-1.1	2.3	-1.2	1.4	1.6	3.1	1.6	-0.3	0.9	2.9	-2.0
Chest pain or discomfort	1.9	2.7	7.6	1.2	-2.2	-2.2	-0.4	-1.1	0.2	-2.2	-2.3	-1.8	-0.3	-0.5	1.6	-0.4	1.8	-1.6	-2.1	-2.8	-1.3	-0.1	-1.6	-2.6	2.1
Illnesses of father: Heart disease	1.9	2.7	7.3	0.9	-2.2	-2.2	-1.2	0.4	0.3	-2.2	-2.2	-2.7	0.3	-1.7	0.2	-0.9	1.5	-2.1	-2.3	-1.4	-2.5	1.0	-1.0	-1.6	1.9
Major Depression (MDD)	1.8	2.2	5.7	-1.6	-2.2	-2.1	-0.9	-1.4	0.3	-2.1	-2.4	-1.4	-1.6	-1.8	-0.3	-0.5	-0.7	-1.9	-2.2	-1.4	-1.7	-1.3	0.6	-1.2	1.0
HDL Cholesterol	1.8	2.9	9.6	-1.8	-2.4	-2.3	-3.1	-0.5	0.3	-2.4	-2.1	-2.0	-0.5	-2.7	-0.8	-2.0	-0.7	-2.2	-2.4	0.8	-1.9	-1.1	0.6	-0.6	-0.6
Neuroticism (2016)	1.8	2.7	7.4	0.2	-2.6	-2.5	-1.4	-1.3	1.5	-2.4	-2.4	-2.0	0.1	-1.2	0.3	-0.3	0.9	-1.9	-2.7	-2.3	-1.1	0.0	-0.5	-2.1	1.4
Nervous feelings	1.8	3.4	9.7	-1.1	-2.9	-2.7	-2.0	-1.2	0.6	-2.6	-2.5	-1.0	-1.9	-1.2	0.9	-1.3	0.3	-2.0	-2.7	-2.6	-1.6	-1.3	0.0	-3.1	0.6
Tense / ‘highly strung’	1.8	2.9	8.6	-1.7	-2.6	-2.5	-2.2	-2.0	0.4	-2.4	-2.1	-1.1	-0.4	-1.5	0.3	-1.4	-0.2	-2.1	-2.6	-1.4	-0.9	-1.8	0.2	-2.9	0.3
Age at last live birth	1.8	2.6	7.5	1.1	-1.6	-1.6	-0.1	1.2	-0.4	-1.7	-1.4	-1.1	-0.4	-0.9	2.2	-0.6	2.3	-2.2	-1.4	-2.4	-1.7	1.2	-2.6	-1.7	2.7
Supplements: Calcium	1.8	1.9	4.8	-1.9	-1.6	-1.3	-1.8	-0.9	1.5	-1.4	-1.2	-1.6	-0.5	-1.3	0.1	-0.6	-1.1	-2.2	-1.3	-0.3	-1.6	-2.2	1.1	-2.1	-1.0
Schizophrenia vs Biploar Disorder	1.7	2.2	8.9	-2.1	-0.1	-0.3	-0.8	-0.4	1.6	-0.2	-0.3	-0.2	-0.6	-0.9	-2.2	1.7	-3.0	0.0	-0.2	1.2	0.4	-2.8	2.7	0.4	-2.8
Prostate Cancer	1.7	2.4	9.1	-2.0	0.5	0.4	-1.1	-1.9	1.3	0.5	0.3	-0.2	-0.8	-0.5	-0.9	1.4	-3.0	0.4	0.3	1.9	0.6	-3.0	2.7	0.9	-3.0
LDL Cholesterol	1.7	2.6	9.6	2.1	2.0	1.9	2.2	1.5	-0.3	2.0	1.8	1.1	1.8	1.6	-0.4	0.1	1.0	2.3	2.1	1.2	0.9	3.1	-0.7	2.0	0.5
Hayfever/allergic rhinitis (self-reported)	1.7	2.2	6.1	1.4	-1.6	-1.4	0.3	1.0	-1.8	-1.5	-1.7	-1.5	0.6	-0.8	2.0	-1.0	2.2	-1.3	-1.5	-1.6	-1.4	1.1	-2.5	-1.7	2.0
Father’s age at death	1.7	2.3	8.2	-1.1	-1.9	-1.4	-0.8	-0.1	-1.1	-1.4	-1.8	-1.6	-1.6	-2.1	-0.6	-2.6	0.2	-2.1	-1.6	-0.2	-2.9	-1.3	-0.8	-2.0	0.4
Number of operations (self-reported)	1.7	2.5	8.8	-3.0	-2.1	-1.8	-1.8	-1.3	0.1	-1.8	-2.1	-0.9	-1.7	-2.2	0.2	-1.7	-0.8	-2.2	-2.0	0.1	-1.0	-1.8	-0.5	-1.7	-0.3
Risk taking	1.7	2.4	6.8	-2.6	-1.3	-1.2	-1.8	-1.6	0.9	-1.1	-1.0	-0.6	-1.5	-1.1	-2.5	-0.6	-2.5	-1.0	-1.1	-0.4	-1.3	-2.6	2.1	-1.3	-2.1
Neuroticism (Nagel 2018)	1.6	3.8	11.3	-2.5	-2.5	-2.1	-2.2	-3.1	1.2	-2.0	-2.0	-0.8	-1.8	-1.1	-0.9	-0.6	-1.6	-1.9	-2.2	-2.0	-1.2	-3.4	1.3	-3.3	-0.9
Lupus	1.6	2.4	5.1	0.3	-2.0	-1.9	-1.8	-1.0	-1.0	-2.0	-1.6	-1.7	1.5	-1.8	0.8	-1.9	0.8	-2.0	-2.0	-1.3	-2.1	1.3	-0.6	-2.3	0.9
Number of incorrect matches in round	1.6	2.7	6.7	-0.6	-2.5	-2.4	-1.2	-1.6	-0.1	-2.4	-2.6	-1.8	-0.5	-2.1	-0.1	-1.0	-0.7	-1.6	-2.5	-2.0	-2.1	-0.8	1.1	-1.9	0.0
High blood pressure (siblings)	1.6	2.3	7.4	-0.6	1.4	1.8	1.2	-1.1	-0.5	1.9	2.0	2.4	0.4	2.0	-0.6	-1.1	-1.6	2.0	1.8	-0.8	0.8	-1.7	2.7	-0.5	-1.7
Forced vital capacity (FVC), Best measure	1.6	5.9	19.5	0.7	3.6	3.8	2.6	-0.6	0.3	3.8	4.0	3.4	0.6	4.4	-1.8	1.8	-0.6	3.2	3.9	-0.4	2.2	-0.1	1.0	0.8	-0.5
Health satisfaction	1.6	2.1	6.5	-1.2	-2.1	-1.8	0.1	-1.8	1.0	-1.9	-2.3	-1.8	-1.0	-1.0	0.5	-0.3	0.2	-1.7	-1.9	-1.4	-1.6	-1.0	-0.9	-2.5	1.0
Ever had bowel cancer screening	1.6	1.8	6.2	-2.5	-0.7	-0.4	-2.3	-1.7	0.7	-0.5	-0.4	-0.1	-1.5	-0.9	-1.0	-0.5	-2.5	-1.0	-0.5	0.1	-0.4	-2.2	1.7	-1.2	-2.3
Ever taken oral contraceptive pill	1.6	1.8	4.6	-0.6	1.9	1.8	0.3	0.0	0.8	1.9	1.6	1.3	-1.2	1.7	-1.8	2.1	-0.9	1.9	1.8	0.5	1.6	-0.9	0.2	0.9	-1.4
Heel T-Score	1.5	12.0	56.7	-2.2	2.3	3.7	2.5	1.9	-4.4	3.4	3.2	7.5	-1.6	3.8	2.6	-6.5	3.4	2.2	3.4	-2.4	2.0	-0.6	-5.0	-2.8	2.7
Ever used hormone-replacement therapy (HRT)	1.5	2.0	7.8	-1.8	-1.2	-1.1	-2.8	0.1	1.2	-1.0	-1.0	-1.1	-1.2	-2.1	-1.9	-0.5	-1.2	-0.7	-1.1	1.9	-0.9	-2.0	1.2	0.2	-1.9
Diverticular disease/diverticulitis (self-reported)	1.5	1.7	5.7	-2.2	-1.3	-1.2	-2.2	-1.0	1.0	-1.3	-1.1	-0.8	-1.8	-1.4	-0.8	-0.4	-0.8	-1.4	-1.4	-0.3	-1.0	-2.4	0.4	-1.6	-1.3
Fluid intelligence score	1.5	3.2	9.3	-1.9	-2.0	-1.6	-1.0	-3.0	0.2	-1.6	-1.4	-1.7	-2.0	-0.9	1.2	-2.1	-1.1	-2.5	-1.4	-2.4	-2.8	-1.7	1.4	-2.7	0.1
Asthma	1.5	2.9	8.8	-1.6	-2.3	-2.2	-1.7	-1.3	0.8	-2.2	-2.0	-3.0	-0.1	-2.8	0.6	-0.7	-1.1	-2.4	-2.4	0.1	-2.1	-1.5	1.0	-1.3	-0.8
Headache pain in last month	1.5	2.6	11.5	-1.9	1.6	1.4	-1.1	-1.5	1.1	1.6	1.6	0.8	-0.3	0.9	-1.8	1.6	-2.1	1.7	1.4	1.7	1.3	-2.0	2.1	0.7	-3.4
Wheeze or whistling in the chest in last year	1.5	2.6	7.1	-0.3	-2.6	-2.6	-1.5	-1.1	0.3	-2.6	-2.6	-2.5	0.4	-2.0	0.6	-0.5	-0.2	-1.7	-2.7	-1.4	-1.5	-0.5	0.2	-1.8	-0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.5	1.8	5.1	0.5	-2.0	-2.0	0.4	-0.8	0.1	-2.0	-2.0	-2.3	0.2	-1.8	1.2	-0.3	0.8	-1.6	-2.2	-0.9	-1.4	0.2	-0.4	-0.8	1.4
Asthma (self-reported)	1.5	3.0	9.6	-1.1	-2.5	-2.4	-1.7	-0.9	1.0	-2.4	-2.1	-3.1	0.0	-2.7	0.6	-0.7	-0.7	-2.5	-2.5	-0.3	-2.3	-1.2	0.8	-1.4	-0.5
Illnesses of father: None of the above (group 1)	1.5	1.8	8.0	-2.6	0.5	0.8	-1.3	-1.6	-0.4	0.7	0.9	1.7	-0.4	0.6	-1.0	-0.8	-2.8	0.4	0.8	0.4	1.1	-2.2	1.9	-0.2	-2.2
Ovarian Cancer	1.4	1.9	4.0	0.4	2.0	1.9	1.9	-1.3	-0.8	1.9	1.8	1.0	1.3	1.7	-0.5	1.3	-0.5	1.6	1.9	1.2	1.4	0.2	1.2	1.6	-0.7
Mean Putamen Volume	1.4	1.6	4.5	0.9	1.6	1.3	1.1	0.9	0.3	1.4	1.5	1.5	-0.1	1.3	-2.1	0.9	-0.6	1.7	1.4	1.0	1.5	0.7	1.1	2.1	-0.5
Other serious medical condition/disability diagnosed by doctor	1.4	1.8	6.0	-1.4	-1.7	-1.5	-1.3	-1.1	-1.1	-1.5	-1.6	-0.7	-0.5	-0.6	-0.3	-1.9	0.1	-1.4	-1.5	-1.6	-1.9	-1.4	-0.7	-2.5	0.5
Fed-up feelings	1.4	2.5	8.5	0.2	1.8	1.6	1.2	-1.7	2.1	1.7	1.6	1.5	0.4	1.9	-1.5	2.9	-1.5	1.9	1.5	0.3	2.3	-0.5	2.1	1.7	-0.6
Falls in the last year	1.4	1.9	5.1	-0.7	-2.1	-2.1	-1.3	-1.0	0.9	-1.9	-2.2	-1.5	0.1	-1.3	-0.6	-0.9	-0.1	-1.5	-2.2	-1.4	-1.4	-0.0	-0.7	-1.9	0.9
Pulse wave peak to peak time	1.4	1.7	5.2	-1.1	1.3	1.4	0.6	-2.3	-1.1	1.3	1.1	1.2	0.5	1.1	-1.9	1.1	-1.9	1.1	1.4	0.7	0.8	-1.1	2.1	0.7	-1.9
Ever had prostate specific antigen (PSA) test	1.4	1.7	4.5	-0.1	-1.9	-1.9	-1.7	-0.1	1.0	-1.9	-1.8	-1.2	-0.5	-1.4	2.1	0.2	-0.1	-2.0	-1.9	-1.4	-0.8	-0.7	-0.6	-1.2	0.5
Lung FVC	1.3	6.8	17.1	1.9	4.1	4.0	1.1	2.2	0.6	4.0	4.1	2.8	1.0	3.5	-1.2	3.1	0.0	3.2	4.0	1.6	3.0	-0.1	0.7	2.7	-1.3
Sensitivity / hurt feelings	1.3	2.2	4.3	-1.9	-1.9	-1.7	-1.9	-1.5	1.9	-1.6	-1.9	-0.5	-1.7	-1.2	-1.0	0.3	-1.5	-1.6	-1.9	-1.6	-0.3	-2.1	1.1	-1.9	-0.4
Eye problems/disorders: Diabetes related eye disease	1.3	1.4	4.4	-1.0	-1.4	-1.2	0.3	-0.3	-0.5	-1.3	-1.3	-1.4	1.0	-1.7	0.5	-1.8	0.5	-2.1	-1.3	-0.1	-1.8	-0.6	-0.8	-1.6	1.2
Vitamin and mineral supplements	1.3	1.8	6.6	1.7	0.8	0.7	2.6	1.0	-2.3	0.8	0.4	1.5	0.0	1.4	0.2	-1.2	1.8	1.6	0.9	-1.0	0.7	1.6	-1.5	0.6	2.2
Impedance of leg (right)	1.3	6.2	14.6	-0.7	-3.5	-3.4	-3.7	-1.2	1.0	-3.5	-3.1	-3.5	-2.0	-2.3	0.4	-1.5	0.5	-3.3	-3.4	-2.0	-3.8	-1.5	-0.6	-3.3	0.8
Relative age voice broke	1.3	2.0	7.8	-1.7	0.9	0.8	-1.0	-0.3	1.8	0.9	1.1	0.3	0.2	0.2	-2.2	1.1	-2.1	0.8	0.8	2.4	1.2	-1.8	2.0	1.2	-2.8
Heel bone mineral density (BMD) T-score, automated (left)	1.3	3.0	13.0	-0.8	1.2	1.9	1.2	1.0	-2.6	1.8	1.9	3.1	-0.4	2.1	0.1	-3.6	1.5	1.5	1.9	-1.5	0.1	-0.4	-2.2	-1.7	0.7
Multivitamins +/- minerals	1.3	1.7	5.0	-1.3	-1.7	-1.5	-1.9	-1.1	1.1	-1.6	-1.4	-1.7	-1.0	-1.6	0.7	0.1	-0.5	-2.2	-1.6	-0.3	-1.3	-1.2	0.3	-1.6	-0.8
Hair/balding pattern: Pattern 3	1.3	1.9	7.3	2.4	0.9	0.5	2.7	1.8	-0.2	0.5	0.5	0.8	1.3	0.9	0.3	0.8	1.9	1.3	0.6	0.3	1.3	2.3	-1.0	2.4	1.7
Happiness	1.3	1.6	4.5	-0.7	-2.0	-2.0	-0.9	-0.1	-0.4	-1.9	-2.1	-1.4	0.0	-1.8	0.2	-1.3	0.7	-1.5	-1.9	-0.2	-1.4	0.2	-0.5	-0.9	1.3
Pulse wave Arterial Stiffness index	1.3	1.5	3.4	1.0	-1.2	-1.3	-0.5	1.8	1.5	-1.2	-1.0	-1.3	-0.6	-1.0	1.7	-0.9	1.6	-1.1	-1.3	-0.8	-0.8	0.9	-1.8	-0.8	1.7
Breastfed as a baby	1.3	1.7	5.6	0.6	1.9	2.2	1.2	0.3	-0.7	2.2	2.4	1.7	1.4	1.7	-1.1	-0.6	-0.2	1.2	2.3	-0.3	0.1	0.1	0.6	0.3	-0.1
Heart disease (mother)	1.3	1.6	7.3	-1.4	-1.4	-1.0	-1.7	-0.9	-1.3	-1.0	-1.1	-0.5	0.2	-1.2	-0.2	-2.7	-0.3	-1.2	-1.1	-1.0	-2.0	-1.8	0.5	-2.0	0.4
Pulse rate, automated reading	1.3	4.2	11.6	-0.9	-3.0	-3.0	-2.3	-0.9	0.5	-3.0	-3.4	-2.6	-1.3	-2.4	0.9	-0.2	0.7	-2.8	-3.2	-2.0	-2.0	-0.5	-0.9	-2.7	0.6
Suffer from ‘nerves’	1.3	2.0	5.6	-0.6	-2.4	-2.2	-0.8	-0.5	0.9	-2.1	-2.0	-1.3	-0.9	-0.9	0.7	-0.9	1.0	-1.7	-2.1	-1.8	-1.1	-0.7	-0.8	-2.2	1.4
Qualifications: NVQ or HND or HNC or equivalent	1.3	1.6	4.6	-0.3	-1.7	-1.8	-1.0	0.3	1.5	-1.8	-1.8	-2.1	-0.6	-2.0	1.3	0.3	-0.1	-1.7	-1.9	0.1	-1.2	0.2	-0.4	-1.0	-0.4
Commuting to job workplace: Car/motor vehicle	1.3	1.5	8.2	-1.9	0.4	0.6	-0.9	-1.2	0.2	0.6	0.5	1.6	-1.5	0.6	0.2	0.3	-1.9	0.5	0.6	-0.0	1.4	-2.9	0.7	-0.8	-2.5
Osteoarthritis (self-reported)	1.3	1.7	5.4	-1.1	0.9	0.8	0.6	-1.1	0.9	0.9	0.7	1.2	-0.5	0.2	-2.3	1.0	-2.2	0.8	0.8	0.4	1.4	-2.3	2.3	1.2	-2.2
Number of self-reported non-cancer illnesses	1.3	2.3	8.0	-1.2	-1.9	-1.9	-2.3	-0.8	0.9	-1.8	-1.7	-1.5	-0.5	-1.5	0.0	-0.9	-1.4	-1.5	-1.9	-0.6	-1.0	-2.8	1.6	-1.6	-1.5
Commuting to job workplace: Cycle	1.3	1.6	5.2	2.3	0.9	0.8	0.7	1.1	1.6	0.7	0.8	0.8	1.6	1.3	0.8	1.1	1.7	0.3	0.8	-0.4	1.1	2.2	-1.4	1.0	2.1
Verbal and Numeric Reasoning (VNR)	1.2	2.8	8.4	-0.8	-2.2	-1.8	-0.4	-2.0	1.3	-1.8	-1.7	-1.4	-1.4	-0.3	1.5	-1.6	0.9	-2.4	-1.7	-2.9	-2.1	-0.1	-0.7	-2.9	1.7
Bipolar Disorder (2011)	1.2	1.2	5.1	-0.6	-1.4	-1.0	0.4	-0.4	-1.4	-1.1	-1.4	-0.2	-1.1	-0.9	-0.9	-2.2	0.3	-1.0	-1.0	-1.5	-1.3	0.3	0.0	-1.3	1.8
Hand grip strength (left)	1.2	3.1	9.2	2.6	1.8	1.7	2.6	1.4	0.2	1.6	2.0	1.6	3.0	2.3	1.0	1.4	1.3	1.7	1.8	-0.1	1.8	2.7	-0.4	1.5	1.2
Number of treatments/medications taken	1.2	2.1	7.4	-2.0	-1.2	-1.3	-2.5	-0.9	1.5	-1.2	-1.1	-1.5	-0.4	-1.5	0.2	0.4	-2.3	-1.0	-1.3	1.0	-0.0	-2.1	1.8	-0.5	-2.7
Ever had hysterectomy (womb removed)	1.2	1.4	7.9	-2.1	-0.2	-0.3	-1.0	-0.3	1.0	-0.3	-0.7	-0.7	-1.5	-1.7	-1.2	0.5	-1.7	-0.1	-0.4	2.8	0.1	-0.3	1.0	1.8	-1.4
Systolic blood pressure, automated reading	1.2	3.5	18.0	1.3	0.4	0.3	2.3	4.2	-2.1	0.3	-0.2	1.7	-0.5	1.3	2.9	-1.2	3.4	1.0	0.5	-1.3	1.2	1.6	-3.6	0.4	2.5
Hand grip strength (right)	1.2	3.3	16.0	2.6	1.7	1.5	2.8	1.5	0.4	1.5	1.9	1.1	4.0	1.9	0.4	2.0	1.3	1.5	1.7	0.8	1.9	2.7	-0.5	2.0	1.1
Seen doctor (GP) for nerves, anxiety, tension or depression	1.2	1.8	4.6	0.0	-1.9	-1.9	-1.2	-0.6	0.9	-1.8	-1.7	-1.5	-1.6	-1.2	0.4	-0.3	0.8	-1.7	-2.1	-1.9	-1.1	-0.2	-0.7	-2.0	0.7
Leg fat percentage (right)	1.2	4.2	10.5	-1.9	-2.8	-2.2	-0.3	-2.0	-2.1	-2.4	-3.2	-2.1	-1.5	-3.0	1.0	-3.2	0.3	-2.2	-2.4	-0.3	-2.8	-0.3	-1.9	-2.4	1.0
Seen a psychiatrist for nerves, anxiety, tension or depression	1.2	1.6	5.2	-1.5	-1.2	-0.9	-1.4	-2.3	1.3	-0.8	-0.8	-0.1	-1.9	-0.4	-1.0	-0.9	-1.4	-0.7	-1.1	-1.0	-0.6	-1.9	1.2	-2.2	-1.1
Age at first live birth	1.2	2.1	8.4	0.0	-1.7	-1.6	-0.6	-0.2	0.7	-1.7	-1.2	-1.6	0.0	-0.7	2.1	-0.4	0.9	-2.5	-1.4	-2.9	-2.0	0.2	-1.0	-2.4	1.6
Medication: Allopurinol	1.2	1.5	8.0	-0.2	1.1	0.7	-0.2	2.8	0.8	0.9	0.9	1.3	-0.1	0.3	-2.0	1.5	-0.6	0.8	1.0	1.5	1.9	-1.2	1.0	2.1	-0.9
Supplements: Vitamin C	1.2	1.5	6.0	-1.5	1.2	1.3	-0.3	-1.7	0.2	1.2	1.2	0.5	0.2	0.2	1.8	1.2	-1.3	0.5	1.1	2.1	1.5	-0.7	0.4	1.0	-2.5
Illnesses of siblings: Diabetes	1.2	1.5	5.3	-0.3	-1.7	-1.4	0.8	-0.8	-0.1	-1.5	-1.8	-1.0	-1.1	-0.8	0.5	-1.5	0.7	-1.4	-1.4	-1.7	-1.3	0.7	-1.0	-2.3	1.3
Breast cancer (self-reported)	1.2	1.4	5.7	-0.2	1.5	1.3	0.1	1.9	0.3	1.4	1.4	0.5	0.7	-0.0	-2.3	0.7	-0.9	1.1	1.4	1.9	0.6	-0.1	1.0	2.4	-0.5
Intelligence (Savage-Jansen 2018)	1.1	3.3	9.4	-0.4	-2.6	-2.3	-1.3	-1.3	-0.4	-2.3	-2.1	-1.7	-0.8	-1.0	1.3	-2.5	1.1	-2.5	-2.1	-2.5	-3.1	0.6	-0.8	-2.3	2.0
Relative age of first facial hair	1.1	2.3	8.4	-2.1	1.2	1.1	-1.1	-0.5	1.1	1.1	1.6	1.5	-1.0	0.7	-1.6	0.5	-2.4	1.4	1.0	1.5	1.9	-1.7	2.4	1.0	-2.9
Impedance of leg (left)	1.1	5.4	12.9	-1.0	-3.2	-3.2	-3.6	-0.9	1.5	-3.2	-2.8	-3.5	-2.4	-2.5	0.1	-1.3	0.1	-3.1	-3.1	-1.0	-3.5	-1.5	-0.1	-2.8	-0.0
Had menopause	1.1	1.3	4.8	-1.7	-1.2	-0.9	-1.2	-0.8	0.6	-0.9	-1.0	-0.3	-1.9	-1.4	-0.2	-2.2	-1.0	-0.8	-1.0	0.7	-1.0	-1.9	0.8	-0.9	-1.3
Impedance of arm (right)	1.1	5.1	22.9	-2.4	-2.7	-2.7	-4.8	0.4	0.2	-2.7	-2.4	-2.1	-2.8	-2.4	0.2	-2.0	-1.0	-2.5	-2.7	-0.6	-2.8	-2.8	0.6	-2.8	-1.3
Medication: Ibuprofen (e.g. Nurofen)	1.1	1.4	5.6	-1.2	1.0	1.0	0.3	-2.4	-0.6	1.0	0.8	1.7	-0.7	0.9	-0.5	0.7	-1.7	1.4	1.0	0.8	1.9	-0.9	1.3	1.0	-1.3
Body fat percentage	1.1	4.3	11.8	-3.2	-2.7	-2.1	-0.8	-1.9	-1.3	-2.3	-2.9	-2.0	-1.9	-3.3	0.1	-3.4	-0.9	-2.2	-2.3	0.5	-2.7	-1.3	-0.5	-2.3	-0.4
Medication: Atorvastatin	1.1	1.3	4.3	2.1	0.4	0.5	1.9	1.1	-0.8	0.4	0.4	0.6	1.6	0.5	0.6	0.0	2.1	0.7	0.5	0.0	0.8	1.9	-1.7	1.2	1.8
Alzheimer’s Disease (in mother)	1.0	1.2	4.2	-0.3	-1.6	-1.5	-2.0	0.3	0.9	-1.5	-1.1	-1.5	0.3	-1.5	0.3	-0.7	0.4	-1.5	-1.6	-0.9	-1.2	0.1	-0.3	-1.1	0.6
Coronary Artery Disease (CAD)	1.0	1.2	4.0	-0.3	1.1	1.0	0.3	0.1	-0.3	1.0	1.1	1.1	1.5	0.7	-1.3	0.2	-0.7	1.9	1.0	2.0	1.6	0.6	1.6	1.4	-1.1
Trunk fat percentage	1.0	4.0	11.6	-3.4	-2.5	-2.0	-1.1	-1.7	-0.8	-2.2	-2.7	-2.0	-2.1	-3.2	-0.2	-3.0	-1.3	-2.2	-2.2	0.6	-2.5	-1.6	-0.1	-2.2	-0.9
Forced vital capacity (FVC)	1.0	3.8	10.6	1.3	3.0	3.0	1.6	-0.0	0.8	3.0	3.3	2.1	1.1	3.2	-2.0	2.0	-0.6	2.4	3.1	0.2	1.4	0.4	1.4	1.4	-0.5
Heart attack	1.0	1.3	5.8	2.4	0.2	-0.0	1.7	1.3	1.6	-0.0	0.2	0.1	1.2	0.7	-0.1	1.1	1.5	0.8	0.1	0.1	1.1	2.1	-0.4	1.3	1.5
Comparative body size at age 10	1.0	2.8	11.8	1.4	-0.2	0.3	3.3	0.9	-2.0	0.3	-0.3	0.4	0.8	0.4	0.9	-2.6	2.5	-0.2	0.2	-1.6	-1.2	2.0	-3.0	-1.1	3.4
Forced expiratory volume in 1-second (FEV1), predicted	1.0	2.1	8.1	0.3	1.6	1.5	2.4	-0.9	1.1	1.6	1.4	1.8	-0.1	2.9	-0.1	2.4	-0.5	1.5	1.7	-1.7	1.9	0.8	0.3	0.1	0.9
Ever had stillbirth, spontaneous miscarriage or termination	1.0	1.1	5.1	1.1	1.2	0.8	0.9	1.4	1.3	0.9	0.8	0.5	0.9	1.6	0.2	2.3	0.1	1.2	1.0	-0.1	1.5	1.0	-0.1	0.9	-0.1
Commuting to job workplace: Walk	1.0	1.0	2.6	0.7	-1.2	-1.2	0.2	-0.0	0.6	-1.3	-1.1	-1.4	0.9	-0.8	1.1	-0.0	0.7	-1.3	-1.2	-1.6	-1.4	1.4	-0.3	-0.9	1.3
Medication: Aspirin	1.0	1.3	4.3	1.5	-1.1	-1.0	-0.5	0.8	-0.2	-1.1	-1.2	-1.1	0.1	-0.7	2.0	-0.9	2.1	-0.9	-1.1	-0.5	-0.6	1.3	-1.9	-1.0	1.6
Tinnitus: Yes, now most or all of the time	1.0	1.2	3.3	0.7	1.5	1.4	1.8	-1.1	-1.6	1.4	0.9	0.5	-0.3	1.5	1.0	0.6	-0.2	1.4	1.4	1.2	0.5	0.6	0.3	1.4	-0.1
Leg fat percentage (left)	1.0	3.7	9.7	-2.4	-2.5	-2.0	-0.2	-1.9	-1.7	-2.1	-3.0	-2.0	-1.7	-3.0	0.7	-3.1	-0.1	-2.1	-2.1	0.4	-2.5	-0.5	-1.5	-2.1	0.3
Irritability	1.0	1.8	7.5	-1.9	-1.4	-1.1	-0.6	-2.0	1.5	-1.2	-0.8	-0.4	0.8	0.2	-2.7	-0.8	-1.4	-0.7	-1.1	-1.9	-0.9	-0.8	1.2	-2.4	0.3
Age when periods started (menarche)	0.9	2.2	7.2	0.9	1.7	1.2	-1.0	1.8	0.5	1.3	2.2	0.4	1.8	0.9	-1.2	0.9	-0.5	1.9	1.5	2.6	1.4	0.1	1.5	2.7	-2.0
Qualifications: CSEs or equivalent	0.9	1.2	4.8	0.6	1.4	1.0	0.3	-0.1	-0.8	1.1	0.9	1.3	0.7	0.7	1.2	1.6	-0.2	1.4	0.9	1.1	2.0	0.8	0.4	2.2	-0.7
Waist circumference	0.9	3.2	8.8	-2.1	-2.4	-2.0	-0.3	-2.2	-1.6	-2.0	-2.7	-2.1	-0.9	-3.0	0.7	-2.6	-0.5	-2.2	-2.2	-0.3	-2.4	-0.2	-0.7	-1.9	0.3
Alcohol intake versus 10 years previously	0.9	1.3	8.5	-0.5	1.1	0.9	2.9	-0.2	0.2	1.0	0.7	0.8	0.4	0.6	-1.3	0.7	-1.2	1.3	1.1	1.4	1.2	1.0	1.1	2.2	-0.2
Pulse rate	0.9	1.6	4.5	-0.7	-1.6	-2.0	-1.6	0.7	1.3	-1.9	-2.1	-1.6	-1.2	-1.2	0.9	1.2	0.7	-1.2	-2.0	-0.5	-0.1	-0.3	-1.0	-1.1	0.0
Depression (self-reported)	0.9	1.1	4.8	-0.1	-0.5	-0.2	-0.7	-1.1	-1.0	-0.2	-0.2	0.3	-0.5	0.4	2.2	-2.0	1.6	-0.3	-0.4	-1.6	-0.8	0.8	-1.4	-1.5	1.4
Medication: Amlodipine	0.9	1.3	10.0	-1.8	-0.4	-0.4	-1.4	-0.6	0.9	-0.4	-0.4	0.1	-1.3	-0.3	-0.1	0.0	-1.5	-0.5	-0.6	-0.5	0.7	-3.2	1.1	-1.7	-2.0
Reason for reducing amount of alcohol drunk: Health precaution	0.9	1.1	4.9	-1.3	0.7	0.9	-0.1	-0.7	-0.2	0.9	1.2	1.0	0.4	-0.3	-1.0	-0.3	-1.6	0.1	0.7	1.0	0.5	-1.8	2.2	0.5	-2.2
Qualifications: College or University degree	0.9	2.7	9.8	-0.8	-1.3	-0.9	-1.4	-1.0	-0.8	-1.0	-0.8	-0.6	-1.1	0.1	3.1	-2.9	2.0	-1.6	-1.0	-2.5	-2.2	0.7	-1.8	-2.9	1.8
Medication: Blood pressure	0.9	1.7	6.4	1.8	1.1	1.0	1.6	-0.4	0.8	1.0	0.9	1.5	0.0	2.1	2.5	1.7	1.0	1.0	1.0	-1.6	2.4	-0.2	-0.7	-0.2	0.5
Medication: Ibuprofen	0.9	1.1	7.5	-1.8	0.5	0.5	-0.1	-2.7	-0.3	0.4	0.2	1.3	-1.1	0.6	0.2	0.7	-1.6	0.8	0.5	0.5	1.7	-0.5	1.0	0.3	-1.1
Hearing aid user	0.9	1.0	6.2	-0.7	-0.4	-0.5	-1.2	0.1	0.9	-0.6	-0.6	-0.6	-1.0	-1.6	-1.7	0.4	-1.1	-0.2	-0.5	2.5	0.0	-0.5	0.9	1.4	-1.3
Commuting to job workplace: Public transport	0.9	1.1	4.7	1.5	0.2	0.3	1.2	0.7	-2.2	0.2	0.2	-0.2	0.7	-0.2	0.3	-1.5	1.8	-0.1	0.2	0.6	-1.2	1.7	-1.1	1.0	2.0
Eye problems/disorders: Glaucoma	0.9	1.1	3.0	-0.3	-1.6	-1.4	1.0	-0.9	-0.8	-1.5	-1.7	-0.1	-0.7	-1.2	1.0	-0.7	0.1	-1.2	-1.5	-1.0	-0.3	-1.5	0.4	-1.1	0.8
Heart attack/myocardial infarction (self-reported)	0.9	1.2	5.7	2.4	0.2	-0.1	1.5	1.3	1.3	-0.1	0.2	0.1	1.2	0.6	0.3	1.0	1.7	0.8	-0.0	-0.0	1.1	2.1	-0.6	1.1	1.4
Alcohol drinker status: Previous	0.9	1.0	2.5	-1.1	-1.4	-1.2	-1.6	-1.2	1.1	-1.4	-1.0	-0.8	0.8	-1.2	-1.1	-0.1	-0.8	-1.3	-1.2	-0.1	-0.9	-0.6	0.7	-0.8	-0.6
Impedance of whole body	0.9	4.8	19.5	-2.0	-2.6	-2.6	-4.4	-0.4	1.2	-2.6	-2.2	-2.3	-3.0	-2.0	-0.1	-1.5	-0.7	-2.6	-2.6	-0.8	-2.8	-2.6	0.7	-2.7	-1.1
Blood Red Count	0.8	7.5	48.3	3.6	2.1	1.6	4.5	0.6	-1.6	1.7	1.1	-1.7	2.9	-2.0	0.2	1.3	0.2	0.3	1.8	6.9	0.4	3.0	0.1	7.0	0.3
Hearing difficulty/problems: Yes	0.8	1.2	4.9	1.2	1.1	0.8	1.4	-0.1	-2.1	0.9	0.4	1.2	0.7	0.9	-0.6	-0.3	-0.0	1.6	0.9	0.3	0.4	1.8	0.8	2.2	0.8
Diabetes (father)	0.8	1.0	3.2	0.6	-1.4	-1.5	0.0	-0.3	-0.0	-1.5	-1.8	-1.8	-1.0	-1.1	0.5	0.3	0.8	-0.9	-1.6	-0.2	-1.3	1.0	-0.8	-0.5	0.4
Townsend deprivation index at recruitment	0.8	1.1	5.8	0.6	0.7	0.3	0.1	-0.7	-0.5	0.3	0.2	0.7	0.6	0.4	-1.9	0.2	-0.7	1.8	0.4	1.7	1.1	1.8	1.1	2.4	-0.2
Past tobacco smoking	0.8	1.4	7.3	0.8	0.5	0.7	2.7	-1.3	-1.7	0.7	0.5	0.8	-0.7	1.0	1.2	-1.7	1.3	0.4	0.8	-1.0	-1.0	1.9	-0.7	-0.6	1.7
Heel bone mineral density (BMD) T-score, automated (right)	0.8	1.8	8.1	-0.6	0.7	1.2	0.5	1.8	-1.4	1.1	1.3	2.2	-0.7	1.5	-0.0	-2.9	1.4	0.8	1.2	-1.6	-0.2	0.0	-2.0	-1.7	0.9
Noisy workplace	0.8	1.0	6.8	1.9	-0.3	-0.6	-0.1	1.3	-0.9	-0.6	-0.5	-0.3	1.1	-0.1	0.5	0.3	1.6	0.3	-0.6	-0.5	-0.0	2.6	-2.0	0.8	0.8
Serious illness, injury or assault of a close relative in last 2 years	0.8	0.9	2.2	1.1	-1.4	-1.5	-0.5	-0.7	0.2	-1.4	-1.5	-0.8	0.8	-0.3	0.9	0.3	0.6	-0.8	-1.3	-1.4	-0.9	0.3	-0.8	-1.1	0.3
Length of working week for main job	0.8	0.9	2.2	0.0	1.0	1.0	-0.6	-0.0	0.0	0.9	1.2	0.8	1.2	0.5	-1.5	1.1	-1.0	1.2	0.9	1.1	0.9	-0.5	1.4	1.3	-0.7
Overall health rating	0.8	1.6	4.3	-0.6	-2.0	-1.8	-0.2	-0.9	1.8	-1.9	-2.0	-1.9	0.2	-1.0	-0.8	0.0	0.0	-1.0	-2.0	-1.6	-1.0	-0.5	-0.3	-2.1	0.5
Medication: Aspirin	0.8	1.0	3.6	1.5	-1.0	-0.9	-0.5	0.5	-0.0	-1.0	-1.2	-0.9	-0.4	-0.6	1.4	-0.8	1.9	-0.7	-1.1	-0.7	-0.4	1.0	-1.7	-1.0	1.5
Average weekly red wine intake	0.8	1.2	3.0	-0.8	-1.5	-1.3	-1.6	-1.3	-0.3	-1.4	-1.3	-0.9	-0.1	-1.1	0.7	-1.1	-0.4	-1.7	-1.2	-1.1	-1.5	-0.5	0.3	-1.7	0.6
Loneliness, isolation	0.8	1.1	2.6	-0.4	-1.4	-1.3	0.4	-0.8	-0.1	-1.3	-1.5	-0.7	-1.3	-1.5	-1.6	-0.1	-0.7	-1.4	-1.2	-0.2	-1.4	-1.4	1.1	-0.3	0.4
Friendships satisfaction	0.8	1.0	2.4	-0.5	-1.3	-1.1	-0.4	-1.3	-1.5	-1.1	-1.5	-1.2	0.3	-1.1	-1.0	-0.9	0.2	-1.1	-1.1	-0.1	-1.6	-0.5	-0.5	-0.7	0.7
Mineral and other dietary supplements	0.8	1.0	4.2	1.7	-0.8	-1.0	0.2	0.8	-0.9	-0.9	-1.0	-0.3	-0.4	-0.4	0.6	-0.6	2.0	-0.4	-1.0	-0.5	-0.7	1.7	-1.6	-0.2	1.9
Fractured/broken bones in last 5 years	0.8	1.0	7.7	0.6	1.1	0.7	-0.4	-0.2	0.6	0.9	0.5	1.0	0.2	1.2	-0.7	2.8	-0.1	1.2	0.6	0.5	1.9	0.7	0.0	1.3	-0.7
Age started oral contraceptive pill	0.8	1.0	4.4	-0.5	-1.1	-0.8	-0.3	-1.1	-0.3	-0.7	-0.7	-1.4	-0.5	-1.7	0.3	-2.0	0.4	-1.4	-0.9	0.4	-2.1	-0.6	-0.6	-1.2	-0.3
Pack years of smoking	0.8	1.1	3.7	0.3	-1.8	-1.9	-0.8	0.1	0.6	-1.9	-1.9	-0.9	-0.2	-1.1	-0.3	0.2	0.6	-1.1	-1.9	-0.8	0.1	0.1	-0.7	-1.1	1.1
Irritable Bowel Disease (IBD)	0.7	1.7	9.5	-1.3	-0.2	-0.2	-0.8	-1.3	3.1	-0.1	-0.0	0.3	-1.3	1.5	-0.6	1.8	-1.2	0.6	0.0	-2.1	0.9	-2.1	1.4	-2.1	-0.8
Ulcerative Colitis (UC)	0.7	1.4	8.4	-0.7	-0.3	-0.4	-1.0	-1.0	2.9	-0.3	-0.1	-0.2	-1.3	1.0	-1.4	1.9	-1.1	0.5	-0.2	-1.3	0.6	-1.8	1.3	-1.5	-0.9
Crohns Disease (2012)	0.7	1.1	2.8	-1.4	0.3	0.6	1.3	-1.6	1.1	0.7	0.6	1.0	-1.4	1.3	-0.1	-0.5	-1.2	0.3	0.7	-1.7	0.1	-1.6	1.3	-1.6	-0.9
Smoking Status	0.7	1.8	5.7	-1.2	0.2	-0.2	-1.6	0.6	2.2	-0.1	-0.1	0.3	-0.6	-0.2	-2.0	2.4	-1.8	0.9	-0.2	1.6	2.1	-1.8	1.3	1.0	-2.3
Supplements: Zinc	0.7	0.8	3.3	-1.1	0.2	0.3	-1.3	-0.2	-0.4	0.2	0.2	-0.9	-0.6	-1.4	-0.9	-0.3	-1.0	-0.5	0.1	1.7	-0.9	-1.7	0.4	0.3	-1.8
Medication: Metformin	0.7	0.9	3.0	0.1	-1.4	-1.3	-0.3	0.4	0.1	-1.4	-1.7	-1.3	-0.9	-1.4	0.8	-0.1	0.6	-1.2	-1.4	-0.6	-1.1	0.7	-0.9	-1.0	0.4
Diabetes (mother)	0.7	0.9	4.4	-0.1	0.1	0.5	0.2	-1.5	-0.7	0.4	0.2	1.0	0.7	1.2	0.6	-1.2	0.9	0.3	0.4	-2.1	0.2	-0.1	-1.3	-2.0	1.1
Medication: Atenolol	0.7	0.9	4.0	1.5	0.6	0.2	1.1	2.0	-0.2	0.4	0.4	0.5	0.0	0.6	0.6	0.2	1.3	0.9	0.3	1.0	1.9	0.1	-0.9	1.5	0.5
Chronic bronchitis/emphysema (father)	0.7	0.9	4.8	-2.2	-0.8	-0.7	-2.1	-0.6	0.6	-0.6	-0.6	-0.0	-1.2	-0.5	0.8	-0.5	-0.5	-0.2	-0.6	0.4	0.0	-1.5	0.0	-0.9	-1.0
Trunk fat mass	0.7	3.1	7.7	-2.6	-2.4	-1.8	0.1	-2.3	-1.1	-2.0	-2.5	-1.9	-1.2	-2.7	0.0	-2.8	-0.9	-2.0	-2.0	-0.1	-2.4	-0.9	-0.2	-2.1	-0.1
Hearing difficulty/problems with background noise	0.7	1.2	3.6	1.1	1.2	1.0	1.6	-0.7	-1.9	1.1	0.7	1.3	1.4	1.3	0.7	0.3	0.4	1.3	1.0	-0.2	1.3	1.3	-0.4	1.5	0.5
Qualifications: None of the above	0.7	1.4	7.0	-0.1	1.0	1.0	0.2	-0.3	1.0	1.0	0.8	0.8	1.2	0.1	-2.6	1.0	-1.1	1.7	0.9	2.1	1.8	-0.6	1.0	1.8	-1.1
Financial difficulties in last 2 years	0.7	1.0	2.1	-0.7	1.4	1.5	0.4	-0.4	-0.2	1.5	1.3	1.1	0.8	0.8	-0.8	0.4	-0.8	1.4	1.2	1.4	1.4	0.2	0.9	0.8	-1.2
Arm fat percentage (right)	0.7	2.9	10.5	-3.0	-2.0	-1.5	-0.4	-1.4	-2.0	-1.6	-2.3	-1.2	-1.4	-2.9	0.5	-3.2	-0.8	-1.6	-1.6	0.8	-2.0	-0.7	-0.6	-1.7	-0.4
Time employed in main current job	0.7	0.8	2.1	0.2	-1.3	-1.0	-1.1	-0.4	1.4	-1.0	-0.7	-0.5	-0.0	-1.1	0.4	-0.8	0.1	-1.3	-1.1	-0.8	-0.9	-0.9	-0.2	-1.4	-0.6
Impedance of arm (left)	0.7	3.0	16.0	-2.0	-1.8	-1.8	-4.0	0.6	0.6	-1.9	-1.5	-1.1	-2.9	-1.4	-0.1	-1.3	-0.9	-1.7	-1.7	-0.3	-1.8	-2.5	0.8	-2.0	-1.3
Hair/balding pattern: Pattern 4	0.7	1.7	9.9	0.5	-1.9	-1.4	0.1	-0.9	1.6	-1.6	-1.3	-0.9	0.3	-0.2	0.8	-0.7	0.7	-1.1	-1.4	-3.1	-1.6	0.1	-0.7	-2.3	0.9
Whole body fat mass	0.7	2.8	7.3	-2.2	-2.2	-1.7	0.5	-2.2	-1.4	-1.9	-2.5	-1.8	-0.8	-2.6	0.2	-2.7	-0.6	-1.9	-1.9	-0.1	-2.3	-0.6	-0.5	-2.0	0.4
Leg fat mass (right)	0.7	2.6	6.5	-1.4	-2.2	-1.8	0.7	-2.4	-1.2	-1.9	-2.5	-2.0	-0.6	-2.3	0.5	-2.1	-0.0	-1.8	-1.9	-0.6	-2.3	0.0	-1.0	-2.0	1.0
Alcohol intake frequency.	0.7	1.6	6.9	-0.0	-1.6	-1.8	0.9	-2.6	0.6	-1.7	-1.8	-1.5	0.7	-1.1	-0.9	0.6	-1.5	-0.8	-1.6	-1.0	-1.0	-0.5	1.9	-0.4	-0.4
Smoking status: Previous	0.7	1.0	3.0	-1.0	-0.3	-0.4	-1.7	0.3	0.7	-0.4	-0.3	-0.8	1.2	-1.3	-0.3	1.1	-1.6	-0.6	-0.5	1.4	0.7	-1.7	0.8	0.8	-1.6
Osteoporosis (self-reported)	0.7	0.8	3.2	0.1	-0.6	-0.9	-1.8	0.1	0.6	-0.8	-0.7	-1.3	1.2	-1.0	-0.6	1.4	-1.1	-0.1	-0.8	1.2	-0.3	-0.6	1.1	1.0	-0.8
Smoking status: Current	0.7	1.0	3.6	1.2	0.6	0.2	-0.3	1.9	1.3	0.4	0.3	0.9	0.0	1.3	-1.9	1.6	0.6	1.8	0.3	-0.3	1.7	0.5	0.1	0.8	0.0
Mother’s age at death	0.7	0.9	4.5	0.3	-1.0	-0.8	0.2	-0.9	-1.0	-0.9	-0.8	-0.5	-1.2	-0.4	1.7	-2.1	0.7	-0.7	-0.8	-0.7	-1.0	0.3	-0.7	-1.0	1.1
Depressed Affect (Nagel 2018)	0.6	1.3	6.0	-1.1	-0.2	0.0	0.7	-2.5	1.1	0.1	-0.3	0.1	-0.5	-0.2	-2.1	1.2	-2.0	-0.0	-0.1	-0.1	0.2	-2.2	2.1	-0.1	-1.2
Body Mass Index (BMI) (2010)	0.6	0.8	4.8	0.5	-0.2	-0.2	2.2	-0.1	-1.2	-0.3	-1.0	-0.1	-0.9	-0.2	1.7	-0.1	1.0	-0.2	-0.2	0.3	0.2	1.1	-1.8	0.2	1.1
HbA1C	0.6	0.6	3.0	1.3	0.2	-0.0	0.2	-0.9	-0.9	-0.1	-0.1	-0.9	1.0	0.1	1.7	1.0	0.8	0.2	-0.0	0.2	0.0	1.6	-0.2	1.2	0.7
Systolic Blood Pressure	0.6	3.2	16.1	0.8	1.0	0.9	2.4	4.0	-1.3	1.0	0.7	2.4	-0.7	2.5	1.6	-0.9	2.8	1.6	1.2	-2.3	1.5	0.9	-2.4	-0.2	1.8
Current tobacco smoking	0.6	0.9	3.4	1.6	0.5	0.2	-0.2	1.8	0.9	0.3	0.2	0.7	0.0	1.1	-1.7	1.4	0.9	1.6	0.2	-0.1	1.4	1.0	-0.1	1.0	0.3
Serious illness, injury or assault to yourself	0.6	0.7	5.8	-1.1	-0.4	-0.3	-0.2	0.4	1.2	-0.4	-0.2	-0.4	0.1	-1.1	-2.4	0.5	-0.8	-0.2	-0.4	1.6	-0.1	-0.9	0.6	0.6	-0.7
High blood pressure (mother)	0.6	0.9	4.6	0.3	-0.5	-0.4	0.3	0.6	-1.0	-0.4	-0.3	-0.2	1.4	0.6	2.1	-1.0	1.2	-0.4	-0.4	-1.9	-0.3	-0.4	-0.9	-1.8	1.1
Prospective memory result	0.6	0.8	3.1	0.6	0.8	0.7	1.4	-0.1	1.3	0.7	0.7	0.5	0.8	1.0	-0.1	1.7	-0.5	1.1	0.7	0.4	1.6	-0.3	1.1	0.5	-0.8
Medication for cholesterol, blood pressure or diabetes	0.6	1.0	2.9	-1.4	-0.8	-0.7	-1.1	0.2	-1.3	-0.7	-0.7	-1.0	-0.8	-1.6	-1.5	-1.1	-0.8	-0.6	-0.7	1.4	-1.7	0.0	0.7	0.4	-1.1
Gout (self-reported)	0.6	0.8	9.5	0.8	0.5	0.2	0.5	3.1	-0.1	0.3	0.4	0.5	0.4	-0.1	-1.4	0.7	0.2	0.2	0.3	0.4	1.2	-0.3	0.5	1.6	0.4
Migraine (self-reported)	0.6	0.7	9.1	-1.0	-0.3	-0.3	-3.0	-0.9	0.9	-0.2	-0.2	-0.5	-0.9	0.1	-0.1	0.5	-0.8	-0.1	-0.4	-0.1	-0.0	-1.0	-0.2	-0.6	-0.6
Comparative height size at age 10	0.6	3.2	10.6	2.5	-1.4	-1.3	3.1	-1.4	-0.5	-1.4	-1.4	-2.1	1.4	-0.3	0.2	-0.3	1.1	-1.9	-1.1	-3.3	-2.9	2.2	-0.3	-1.0	3.2
Financial situation satisfaction	0.6	0.7	1.9	-1.3	-1.1	-1.1	-0.9	-1.4	-0.1	-1.0	-1.2	-0.4	-1.2	-1.1	0.1	-0.1	-0.9	-0.7	-1.0	0.1	-0.2	-0.7	0.6	-0.9	-0.1
Supplements: Fish oil (including cod liver oil)	0.6	0.8	3.5	-0.9	0.9	1.1	0.2	-0.8	0.8	1.0	1.0	0.4	0.2	0.8	-0.1	0.9	-1.4	0.8	1.2	0.4	0.9	-1.2	1.0	0.0	-1.9
Medication: Bendroflumethiazide	0.6	1.0	4.3	0.4	1.0	1.1	0.8	0.0	-0.7	1.1	0.9	2.1	-1.1	1.5	1.2	-0.6	0.4	1.3	1.1	-1.4	1.1	-0.0	-0.7	-0.6	-0.3
Average weekly beer plus cider intake	0.6	0.8	4.0	0.7	1.0	0.9	-0.4	1.8	-0.3	0.8	1.2	0.1	2.0	0.6	0.2	0.5	0.5	1.1	1.0	1.4	0.3	1.0	-0.1	0.7	-0.6
Diastolic blood pressure, automated reading	0.6	1.7	10.1	0.9	0.9	0.5	1.8	3.2	-1.3	0.6	0.2	1.4	-0.5	1.0	1.4	0.3	1.8	1.4	0.6	-0.4	1.6	1.4	-1.5	1.9	1.2
Medication: Omeprazole (e.g. Zanprol)	0.6	0.8	2.4	0.0	-0.7	-0.6	0.8	-1.5	0.4	-0.7	-0.6	-1.2	1.2	0.2	-0.8	0.3	-0.6	-0.4	-0.7	-1.5	-1.0	-1.2	0.7	-1.5	-0.4
Heart disease (siblings)	0.6	0.7	1.8	1.1	-0.9	-1.1	-0.5	1.1	1.3	-1.0	-0.7	-1.0	1.2	-0.7	-0.3	-0.3	0.9	-0.4	-0.9	0.1	-0.7	1.3	-0.2	-0.1	0.8
Leg fat mass (left)	0.6	2.2	5.2	-1.5	-2.0	-1.5	0.9	-2.3	-1.1	-1.7	-2.3	-1.9	-0.5	-2.3	0.3	-2.1	-0.2	-1.6	-1.7	-0.3	-2.1	-0.0	-0.8	-1.8	0.6
Triglycerides	0.5	0.8	2.2	0.8	1.4	1.4	0.8	0.9	-0.3	1.5	1.3	1.2	0.4	1.2	-0.4	0.7	-0.1	1.4	1.5	0.0	0.8	-0.0	-0.2	0.5	-0.4
Angina	0.5	0.7	1.5	0.6	-1.2	-1.1	0.7	0.7	-0.0	-1.2	-1.2	-1.0	0.0	-1.2	0.7	-0.8	1.0	-1.0	-1.0	-0.1	-0.6	0.1	-0.8	-0.5	1.2
Severe depression (siblings)	0.5	0.6	1.4	-0.2	-1.0	-1.0	-0.4	-0.1	0.4	-1.0	-1.0	-0.8	-1.0	-1.2	-1.1	-0.6	-0.2	-1.2	-1.0	0.3	-1.0	-0.0	0.7	-0.2	-0.3
Average weekly fortified wine intake	0.5	0.6	2.9	0.8	0.3	0.3	-0.1	0.1	-0.0	0.3	0.3	0.2	-0.0	0.3	1.6	-0.1	1.7	-0.0	0.3	-0.4	0.5	1.7	-1.6	0.2	1.1
Medication: Levothyroxine sodium	0.5	0.8	4.9	-0.3	0.7	0.3	-0.3	0.3	-0.5	0.5	0.6	0.0	-0.2	-0.4	-2.2	-0.4	-1.4	0.4	0.5	1.2	-0.5	-0.8	1.9	1.6	-1.0
Alcohol usually taken with meals	0.5	0.8	4.8	-0.4	-1.0	-0.6	0.1	-2.2	0.7	-0.7	-0.8	-1.3	-0.1	-0.6	0.8	0.4	-0.8	-1.4	-0.7	-1.1	-1.1	-0.4	0.5	-1.2	0.2
Medication: Simvastatin	0.5	0.8	3.3	1.4	-1.0	-1.1	-0.6	-0.1	1.4	-1.1	-1.4	-0.7	-0.0	-0.4	0.5	0.3	0.6	-0.8	-1.1	-0.7	-0.1	0.8	-0.3	-0.5	1.8
Qualifications: A levels/AS levels or equivalent	0.5	1.0	5.1	-0.3	0.6	0.9	1.5	-2.0	-1.0	0.9	0.9	0.4	-0.5	1.2	2.3	-1.2	0.2	-0.0	0.9	-1.1	-0.9	0.9	0.1	-0.9	0.8
Medication: Cholesterol lowering	0.5	0.8	3.9	1.7	-0.6	-0.6	-0.1	0.2	1.3	-0.6	-0.6	0.3	0.0	0.5	0.8	0.1	1.2	-0.3	-0.6	-1.8	0.4	0.6	-0.9	-0.8	2.0
Arm fat mass (right)	0.5	2.2	6.6	-2.0	-1.9	-1.5	0.6	-2.0	-1.4	-1.6	-2.3	-1.5	-0.4	-2.6	0.1	-2.3	-0.9	-1.5	-1.7	0.0	-1.9	-0.1	-0.1	-1.3	0.3
Loud music exposure frequency	0.5	0.5	2.9	-0.5	0.5	0.6	1.7	-0.3	-0.1	0.6	0.5	1.4	-1.2	0.9	-0.4	-0.1	-0.5	0.9	0.8	0.2	1.0	-0.6	0.4	0.3	-0.2
Blood clot in the leg (DVT)	0.5	0.6	4.1	-1.5	-0.6	-0.3	-0.8	-1.0	0.0	-0.4	-0.3	0.0	-0.7	-0.8	-0.4	-0.8	-1.1	-0.4	-0.4	0.2	-0.1	-0.7	1.0	-0.7	-2.0
Medication: Paracetamol	0.5	0.8	2.8	-1.4	1.0	1.0	-1.1	0.1	0.1	1.1	1.0	0.8	0.2	0.7	-0.7	0.6	-0.6	1.7	1.0	1.3	1.0	-0.1	0.3	0.5	-1.5
Hypothyroidism/myxoedema (self-reported)	0.5	0.9	4.3	-1.2	0.3	0.1	-0.5	-0.1	-0.3	0.2	0.4	-0.2	-0.5	-0.6	-2.1	-0.4	-1.7	0.4	0.2	1.6	-0.5	-1.3	1.8	0.9	-1.6
Exposure to tobacco smoke outside home	0.5	0.6	4.1	-0.8	-1.0	-0.7	-0.9	-0.4	-0.8	-0.7	-0.5	-0.5	0.4	-0.9	0.2	-2.0	-0.0	-1.0	-0.7	0.2	-1.4	0.2	-0.4	-0.7	0.5
Mouth/teeth dental problems: Loose teeth	0.5	0.6	2.4	-0.9	0.7	0.9	-1.3	-0.8	-0.0	0.8	1.1	0.7	0.7	0.2	-0.9	-0.5	-0.6	0.4	0.9	1.5	0.1	-0.4	-0.1	-0.0	-1.5
Angina (self-reported)	0.5	0.7	1.7	0.7	-1.1	-1.0	0.9	0.7	0.2	-1.1	-1.1	-1.0	0.2	-1.1	0.8	-0.5	1.1	-1.0	-0.9	-0.1	-0.3	0.1	-0.9	-0.5	1.3
Leg pain on walking	0.5	0.6	2.9	-0.9	-0.8	-0.6	0.2	-1.0	-1.1	-0.7	-0.7	-0.4	-0.0	-0.6	-0.6	-1.7	-0.5	-0.7	-0.6	-0.8	-1.4	0.2	-0.3	-0.9	0.1
Arm fat percentage (left)	0.5	2.1	9.7	-3.1	-1.5	-0.9	0.0	-1.2	-1.7	-1.1	-1.8	-0.6	-1.6	-2.4	0.1	-2.9	-1.0	-1.2	-1.1	1.0	-1.4	-1.0	-0.4	-1.4	-0.6
Qualifications: nursing, teaching	0.5	0.7	3.1	-0.9	0.2	0.6	0.0	-1.2	-0.2	0.6	0.5	0.8	-1.8	0.9	1.3	-1.5	0.0	-0.2	0.6	-0.8	-0.5	-0.3	-0.8	-1.6	-0.5
Back pain experienced in last month	0.5	0.7	3.6	-0.9	-1.2	-0.9	-0.7	-0.6	0.7	-1.0	-1.0	-0.7	0.3	-0.5	-0.3	-0.5	-0.9	-0.6	-1.0	-1.1	-1.0	-0.7	0.9	-1.9	-0.4
Wears glasses or contact lenses	0.5	0.6	2.1	-0.6	-1.2	-1.2	-1.3	0.2	0.2	-1.2	-1.4	-0.2	-1.1	-1.0	0.6	-0.6	-0.4	-0.9	-1.1	-0.6	-0.3	-0.5	-0.0	-0.3	0.2
Medication: Lisinopril	0.5	0.7	4.3	-1.4	-0.1	0.1	-0.0	-2.1	-1.1	0.1	0.0	1.4	-0.6	0.5	1.1	-1.5	-0.1	0.1	0.1	-0.4	0.6	0.1	-0.2	-0.9	-0.1
Alcohol drinker status: Never	0.5	0.6	2.9	0.7	0.3	0.3	0.6	-1.0	-1.5	0.3	0.4	0.3	0.5	1.4	1.7	-0.8	0.3	0.8	0.5	-0.8	-0.4	0.6	0.2	-0.6	0.5
Myopia	0.5	0.7	4.3	-1.1	-0.9	-0.8	-2.1	-0.8	0.6	-0.8	-0.7	-0.6	-0.9	-0.5	-0.4	-1.0	-0.9	-0.8	-0.9	-0.0	-0.7	-0.2	0.3	-1.0	-0.3
Bipolar Disorder (2018)	0.4	0.6	3.4	0.9	-0.3	-0.1	0.6	-0.0	-1.8	-0.0	-0.3	-0.5	0.6	0.0	-0.1	-1.1	0.7	0.1	-0.0	-1.2	-1.3	0.9	-0.3	-0.1	1.4
Depression (Nagel 2018)	0.4	0.5	2.7	0.4	-0.3	0.0	1.3	0.4	-1.4	-0.1	-0.4	0.5	-0.0	0.2	0.6	-0.8	1.4	0.1	-0.0	-0.5	0.0	0.4	-1.6	-0.2	1.6
Crohns Disease (2017)	0.4	0.9	4.9	-1.0	-0.1	0.0	-0.1	-1.1	2.2	0.1	0.1	0.4	-0.5	1.3	0.6	0.9	-0.6	0.2	0.1	-2.1	0.5	-1.0	1.0	-1.7	-0.1
Rheumatoid Arthritis	0.4	0.6	2.0	-0.1	-1.0	-1.1	-0.2	0.1	1.4	-1.0	-1.0	-0.8	-1.2	-0.6	0.6	0.7	-0.6	-0.7	-0.9	-0.4	-0.2	-0.6	0.6	-0.7	-0.5
Ulcerative Colitis	0.4	0.6	2.0	-0.9	0.3	0.3	-0.5	-0.4	0.6	0.4	0.6	0.8	-0.7	1.3	-1.4	0.5	-0.5	0.8	0.5	-1.0	0.5	-1.1	0.6	-1.4	-0.5
Height	0.4	7.3	28.4	-0.0	-3.6	-3.2	-0.5	-5.3	2.4	-3.3	-2.8	-2.8	-0.6	-0.9	-0.6	-0.7	-1.4	-2.9	-3.2	-5.1	-3.4	-0.6	1.8	-4.1	1.4
Medication for hormone replacement therapy	0.4	0.4	2.4	-1.5	0.0	0.1	-0.6	-0.2	0.1	0.1	0.4	-0.1	0.4	-0.1	0.4	-0.5	-0.9	-0.1	0.3	1.2	-0.0	-1.2	1.0	0.1	-1.1
Medication: Co-codamol	0.4	0.5	1.5	0.1	-0.8	-0.9	0.8	-0.4	-0.5	-0.9	-0.9	-1.1	0.8	-0.8	0.9	-0.9	0.2	-1.2	-0.8	0.0	-0.6	0.3	-0.0	-0.3	0.5
Pack years adult smoking proportion	0.4	0.6	2.0	0.2	-1.2	-1.4	-0.7	0.4	0.6	-1.4	-1.3	-0.4	-0.2	-0.6	-0.6	0.5	0.5	-0.6	-1.4	-0.4	0.6	0.1	-0.4	-0.6	0.7
Pain all over the body in last month	0.4	0.4	3.7	0.7	-0.2	-0.2	1.3	-1.2	-1.9	-0.1	-0.7	0.1	0.5	0.0	0.2	-0.4	0.1	-0.2	-0.1	-0.3	0.1	0.3	-0.3	-0.4	0.9
Number of live births	0.4	0.5	4.0	-0.9	-0.0	0.2	-1.3	-2.0	-0.3	0.1	-0.2	-0.3	-0.7	-0.7	1.0	-0.2	-0.5	-0.3	0.0	1.1	0.0	-0.2	-0.7	-0.4	-0.7
Pulse wave reflection index	0.4	0.5	2.3	0.6	-0.4	-0.5	-0.7	0.7	-1.0	-0.4	-0.1	-0.8	1.2	-1.0	0.4	-1.5	0.1	-0.4	-0.5	0.4	-1.0	0.1	0.1	0.6	0.7
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	2.1	-0.3	0.3	0.3	-1.4	-0.9	-0.7	0.2	0.4	1.2	0.4	1.0	1.1	-0.5	0.7	0.4	0.4	-1.0	0.6	0.1	-1.0	-1.1	0.4
Birth weight	0.4	0.8	3.1	1.8	-0.8	-0.9	0.2	-0.6	-0.1	-0.8	-0.8	-0.8	0.9	0.0	0.7	0.3	1.5	-0.9	-1.0	-1.8	-0.8	0.7	-0.7	-0.7	1.3
Number of full brothers	0.4	0.5	1.8	-1.2	0.5	0.6	0.4	-1.3	-1.2	0.6	0.3	1.2	-0.2	0.2	0.3	-0.5	-0.1	0.7	0.7	1.3	1.2	0.6	-0.1	0.6	-0.3
Medication for pain relief, constipation, heartburn	0.4	0.6	2.4	0.5	-0.9	-0.9	0.2	0.8	0.0	-0.9	-0.8	-0.8	-0.2	-1.0	0.1	-0.7	0.8	-1.6	-0.9	-0.9	-1.3	0.5	-0.4	-0.4	1.4
Medication: Omeprazole	0.4	0.5	3.1	0.5	-0.6	-0.5	1.0	-0.4	0.3	-0.6	-0.5	-1.2	1.8	0.0	-0.7	0.3	0.3	-0.4	-0.6	-0.9	-0.7	-0.3	-0.2	-1.0	0.3
Medication: Seretide 50 evohaler	0.4	0.4	2.3	0.1	-0.5	-0.6	-0.4	-0.0	-0.5	-0.6	-0.6	-0.2	1.4	0.2	1.1	1.0	0.5	0.1	-0.6	-1.5	0.5	0.2	-0.5	-0.4	0.9
Knee pain experienced in last month	0.4	0.6	3.0	-1.7	-0.4	-0.5	-0.4	-0.8	-0.4	-0.5	-0.5	-0.1	0.6	-0.8	-1.2	0.3	-1.2	-0.3	-0.5	1.0	0.4	-1.0	1.2	0.4	-1.3
Handedness (chirality/laterality): Left-handed	0.4	0.5	1.8	-0.1	0.6	0.5	-1.2	-0.5	-0.5	0.5	0.5	0.8	0.2	1.0	-0.2	0.1	-1.1	1.3	0.5	-0.8	1.0	-0.2	0.8	0.3	-1.0
Mood swings	0.4	0.8	4.0	-1.6	-0.3	-0.1	-0.2	-1.2	2.0	-0.0	-0.1	-0.1	-0.2	-0.1	-1.9	0.9	-1.4	0.0	-0.3	-0.2	0.2	-1.2	1.2	-0.6	-0.5
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	2.4	-1.2	-0.9	-0.6	-1.4	-0.5	-0.2	-0.7	-0.8	-0.5	-1.6	-0.6	0.1	-1.1	0.1	-0.5	-0.7	0.1	-1.0	-1.0	-0.2	-1.1	0.0
Arm fat mass (left)	0.4	1.6	4.8	-2.2	-1.5	-1.0	0.9	-1.9	-1.3	-1.1	-1.8	-1.0	-0.4	-2.1	-0.1	-2.2	-0.8	-1.3	-1.2	0.2	-1.5	-0.2	-0.2	-1.2	0.2
Pain type(s) experienced in last month: Hip pain	0.4	0.5	2.6	-0.6	-0.6	-0.5	-1.1	-0.4	-1.0	-0.6	-0.4	0.1	0.9	-0.7	0.0	-1.6	-1.1	-0.7	-0.4	-0.6	-0.8	-0.4	1.0	-0.5	-0.0
Medication: Paracetamol	0.4	0.6	3.2	-1.8	0.3	0.6	-1.2	-0.4	-0.1	0.6	0.6	0.4	0.3	0.3	-0.3	-0.3	-0.8	1.2	0.6	0.7	0.2	-0.4	0.3	-0.5	-1.7
Ever smoked	0.4	0.6	5.1	0.2	-0.7	-0.9	-2.2	0.7	1.0	-0.8	-0.7	-0.9	0.5	-0.5	-0.7	1.0	-0.2	-0.5	-0.9	-0.6	0.2	-0.7	0.1	-0.2	-0.5
Ever depressed for a whole week	0.4	0.5	2.0	-1.1	-0.4	-0.5	-0.5	-0.7	1.0	-0.4	-0.5	-0.6	-0.9	-0.7	-1.4	0.6	-0.7	-0.5	-0.5	0.6	-0.0	-0.5	0.9	0.2	-0.7
Primary Biliary Cirrhosis	0.3	0.4	3.2	-0.4	0.5	0.5	0.2	0.8	-0.1	0.6	0.4	1.0	-1.8	0.4	0.1	-0.8	0.0	1.0	0.6	0.7	0.2	0.5	0.0	0.6	-0.0
Type 2 Diabetes (T2D) (2012)	0.3	0.4	1.3	0.1	0.6	0.7	0.7	0.7	0.3	0.7	0.6	0.8	-0.5	0.4	-1.0	-0.0	-0.1	0.7	0.7	0.7	0.4	-0.8	-0.6	0.1	-1.1
Blood White Count	0.3	2.5	16.9	1.7	1.1	0.8	-0.2	2.5	-0.2	0.7	0.7	-0.7	0.1	-0.9	0.9	1.1	1.6	0.8	0.9	4.1	0.8	1.6	-2.0	3.6	-0.3
Tanning	0.3	3.5	14.1	0.7	2.2	1.8	1.5	2.1	0.9	1.8	1.8	1.2	0.1	0.8	0.8	3.0	0.3	1.8	2.0	3.5	2.7	0.7	-0.1	3.8	-1.9
Average weekly spirits intake	0.3	0.4	2.1	-0.1	0.1	0.1	0.9	1.4	-0.5	0.2	0.0	0.3	-1.2	0.3	-0.4	-0.9	1.0	0.3	0.2	0.2	-0.0	-0.5	-1.4	-0.3	0.5
Frequency of depressed mood in last 2 weeks	0.3	0.4	1.7	-0.1	-0.4	-0.2	0.8	0.0	-1.2	-0.2	-0.5	0.3	0.6	0.0	0.7	-0.8	0.6	-0.3	-0.2	-0.5	0.2	0.6	-1.1	-0.5	1.3
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	2.4	-0.6	-0.2	-0.2	0.1	0.0	0.3	-0.3	-0.5	-0.7	-0.2	-0.7	-1.5	0.1	-0.8	0.1	-0.4	1.3	-0.4	-0.2	0.4	0.5	-0.5
High blood pressure	0.3	0.8	5.3	0.7	0.0	-0.3	0.1	0.3	0.5	-0.1	-0.1	1.0	-0.9	1.1	2.3	-0.3	0.6	0.5	-0.2	-2.1	1.2	-1.0	-0.2	-0.8	-0.2
Supplements: Glucosamine	0.3	0.4	1.5	-1.1	0.2	0.6	0.8	-0.8	1.2	0.6	0.4	0.3	-0.1	0.4	-1.1	0.1	-0.9	-0.1	0.6	0.1	-0.1	-1.0	0.6	-0.1	-0.7
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	2.6	-0.6	-0.2	-0.0	0.9	-0.9	1.4	-0.0	-0.1	0.1	-0.9	0.4	-1.6	0.7	0.1	0.1	-0.0	-0.6	0.3	-0.1	0.0	-0.1	0.3
Illnesses of siblings	0.3	0.4	2.3	-0.1	0.1	-0.1	-0.4	0.4	-0.4	-0.2	-0.3	-1.0	0.1	-1.0	0.0	1.0	0.0	-0.9	-0.2	1.4	-0.0	0.8	-0.9	1.5	0.2
Trunk fat-free mass	0.3	1.8	13.0	1.8	0.3	0.4	3.6	-2.0	-0.7	0.3	0.1	0.1	2.2	0.8	-0.1	0.9	0.4	0.4	0.4	-1.7	0.1	2.4	-0.1	0.5	2.0
Trunk predicted mass	0.3	1.6	12.3	1.7	0.2	0.3	3.5	-2.0	-0.7	0.2	-0.0	0.0	2.1	0.7	-0.1	0.8	0.3	0.3	0.3	-1.7	0.0	2.3	-0.1	0.4	1.9
Exposure to tobacco smoke at home	0.3	0.4	2.4	0.5	-0.3	-0.4	-0.3	0.4	-0.2	-0.4	-0.1	-0.6	1.2	0.0	-0.2	-0.3	0.9	0.5	-0.1	1.1	-0.2	1.6	-1.1	0.1	0.2
Birth weight of first child	0.3	0.5	2.6	0.7	-0.5	-0.4	-0.6	0.5	-1.3	-0.4	-0.5	0.2	0.0	-0.3	0.3	-1.6	1.0	-0.4	-0.5	-0.9	-0.7	0.1	-0.9	-1.1	0.4
Ever highly irritable/argumentative for 2 days	0.3	0.4	1.2	0.3	-0.8	-0.8	0.4	0.1	0.6	-0.7	-1.1	-1.0	0.0	-1.1	-1.1	-0.2	0.1	-0.6	-0.9	0.3	-0.5	0.4	-0.2	0.7	0.4
Qualifications: O levels/GCSEs or equivalent	0.3	0.5	2.9	0.4	0.0	0.1	1.3	-0.7	-0.5	0.1	0.2	-0.4	0.3	0.7	1.3	-0.0	-0.4	-0.6	0.2	-1.7	-0.9	0.5	0.7	-1.1	0.3
Chronic bronchitis/emphysema (mother)	0.3	0.4	1.3	-1.1	0.5	0.5	-1.1	0.8	0.7	0.6	0.4	0.1	-0.8	0.3	-0.7	0.4	-0.3	0.4	0.5	0.7	0.6	-0.4	-0.6	-0.3	-0.8
Number of children fathered	0.3	0.3	2.6	-0.9	0.2	0.5	1.6	0.4	0.5	0.5	-0.1	-0.2	-0.5	0.2	0.9	0.3	-0.4	-0.3	0.5	0.4	-0.1	-0.6	-0.5	-0.7	0.5
Number of full sisters	0.3	0.4	2.0	0.8	0.4	0.4	-1.4	-1.0	-0.5	0.4	0.5	0.5	0.4	0.1	-0.1	-0.5	-0.0	0.8	0.4	0.6	-0.2	1.0	0.4	1.2	0.1
Hypertension (Self-reported)	0.3	0.7	4.5	0.6	-0.2	-0.5	0.2	0.4	0.8	-0.3	-0.3	0.9	-0.6	1.0	2.1	-0.0	0.6	0.5	-0.4	-2.1	1.3	-1.2	-0.1	-0.8	-0.2
Medication for cholesterol	0.3	0.4	2.8	0.4	0.1	0.3	0.7	-0.8	0.0	0.1	0.3	-0.1	-0.1	0.4	0.1	0.5	1.1	-0.3	0.2	-0.9	-0.4	0.6	-1.7	-0.8	1.4
Average weekly champagne plus white wine intake	0.3	0.4	3.2	-0.3	0.6	0.5	-0.0	0.1	0.1	0.4	0.5	-0.1	-0.8	-0.2	0.2	0.6	-0.6	-0.2	0.4	1.4	0.1	-0.0	1.1	1.8	-0.3
Miserableness	0.3	0.5	2.9	-0.8	-0.6	-0.5	0.4	-1.7	0.5	-0.5	-0.6	-0.6	-0.4	-0.9	-1.4	0.1	-0.7	-0.7	-0.7	-0.1	-0.2	-0.3	0.7	-0.2	-0.1
High cholesterol (Self-reported)	0.3	0.5	3.5	1.9	-0.8	-1.1	0.4	0.1	0.2	-1.0	-1.3	-1.0	0.1	-0.7	0.5	0.5	0.3	-0.7	-0.9	-0.2	-0.3	0.1	0.4	0.4	0.7
Arm fat-free mass (left)	0.3	1.3	9.0	1.1	-0.4	-0.2	3.0	-2.5	-0.3	-0.3	-0.6	-0.6	1.9	-0.1	-0.4	0.3	-0.1	-0.2	-0.3	-1.5	-0.6	2.0	0.1	-0.0	1.7
Unable to work because of sickness or disability	0.3	0.4	1.7	-0.6	-0.8	-0.9	-0.5	0.3	0.9	-0.9	-1.3	-0.1	-0.6	-0.8	-0.7	0.5	-0.5	-0.1	-0.9	0.5	0.6	-0.1	-0.0	0.4	-0.2
Cholesterol lowering medication	0.3	0.4	1.1	0.7	-0.9	-0.8	-0.1	0.3	-0.6	-0.7	-1.0	-0.8	0.4	-1.1	0.1	-0.6	0.1	-0.6	-0.8	0.6	-0.8	0.3	0.5	0.6	0.5
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	3.0	-1.0	-0.6	-0.4	-0.6	-0.6	0.3	-0.4	-0.3	-0.1	-0.5	-0.7	-0.4	-0.5	-0.6	-0.5	-0.4	0.2	-0.1	-0.4	0.6	-0.6	-1.7
Arm predicted mass (left)	0.3	1.3	10.8	1.2	-0.1	0.1	3.3	-2.4	-0.4	0.0	-0.3	-0.4	1.8	0.2	-0.3	0.3	0.0	0.0	0.0	-1.5	-0.5	2.0	0.0	0.1	1.7
Bipolar Disorder or Schizophrenia	0.2	0.5	4.4	0.1	0.0	0.3	0.8	-0.5	-2.1	0.4	0.2	0.3	0.5	0.2	-0.2	-2.0	0.2	0.5	0.4	-0.6	-1.0	-0.1	-0.2	-0.7	0.6
Schizophrenia (2018)	0.2	0.4	2.7	-0.7	0.2	0.4	0.4	-0.6	-1.2	0.5	0.5	0.7	0.2	0.3	-0.2	-1.6	-0.3	0.6	0.5	0.3	-0.3	-0.9	0.0	-0.9	-0.3
Alzheimer’s Disease (in father)	0.2	0.3	0.8	0.1	0.3	0.6	0.2	-0.9	-0.3	0.6	0.5	0.7	-0.6	0.2	0.9	-0.4	0.6	0.4	0.6	0.0	-0.2	0.7	-0.6	-0.4	-0.1
Breast Cancer	0.2	0.4	2.8	-1.0	0.1	0.3	-0.4	-0.3	-0.6	0.3	0.3	0.7	-1.4	-0.2	-0.3	-0.4	-0.5	-0.3	0.3	0.1	0.2	-1.7	0.2	-0.9	-1.0
Age at First Birth	0.2	0.3	1.7	-1.0	0.1	0.2	-0.5	0.5	-1.3	0.1	0.4	0.7	-0.5	-0.2	0.4	-1.3	-0.3	-0.1	0.2	-0.1	0.1	-1.1	-0.4	-0.1	-0.2
Fasting Glucose	0.2	0.2	1.7	0.2	0.5	0.2	0.1	-0.4	-0.3	0.1	0.1	0.2	0.6	-0.3	0.0	0.5	-0.6	0.3	0.2	1.1	0.6	-0.1	0.4	1.3	-0.5
Schizophrenia (2014)	0.2	0.3	0.9	-0.5	0.2	0.4	0.9	-0.8	-0.7	0.4	0.4	0.6	0.8	0.4	-0.8	-0.9	-0.5	0.7	0.5	-0.1	-0.2	-0.9	0.3	-0.6	-0.1
Blood Eosinophil Count	0.2	1.2	4.9	-0.7	-0.3	-0.4	1.6	-0.1	-0.6	-0.5	-0.9	-0.9	-0.2	-1.9	-1.5	0.3	-1.7	-0.1	-0.3	2.0	0.1	-0.8	1.4	2.2	-0.9
BMI	0.2	0.9	5.5	-1.5	-0.6	-0.1	2.4	-1.4	-1.1	-0.2	-1.1	-0.3	-0.5	-1.7	-0.3	-1.4	-0.3	-0.6	-0.3	0.6	-0.7	0.1	-1.1	-0.6	0.1
Cardiovascular Disease	0.2	0.6	2.9	0.7	0.0	-0.3	0.2	0.6	1.7	-0.2	-0.2	0.5	-0.3	0.7	1.5	1.2	0.1	0.4	-0.3	-1.2	1.4	-1.1	0.8	0.1	-0.6
Chronotype (morning person)	0.2	0.4	1.8	-0.4	0.3	0.4	0.7	-0.9	1.3	0.3	0.4	0.5	-0.1	0.7	-0.6	0.6	-0.9	0.6	0.5	-0.0	0.6	-0.9	0.9	0.2	-0.0
Leg fat-free mass (left)	0.2	0.9	8.7	0.2	0.6	0.8	2.9	-1.5	-0.4	0.7	0.5	0.7	1.5	0.9	-0.4	0.3	-0.5	0.7	0.8	-1.0	0.5	1.1	0.5	0.1	0.9
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.2	0.9	0.0	0.3	0.4	1.0	0.3	-0.9	0.4	0.2	0.5	0.3	0.5	-0.4	-0.4	0.3	0.6	0.4	0.5	0.6	0.3	-0.6	0.4	0.5
Sitting height	0.2	1.7	5.9	2.0	-1.5	-1.5	0.0	-1.4	0.5	-1.6	-1.4	-1.2	-0.1	-0.2	-0.1	0.0	1.2	-0.9	-1.5	-2.4	-1.4	2.2	-0.3	-0.9	2.1
Body mass index (BMI)	0.2	0.7	3.0	-1.4	-0.3	0.1	1.7	-1.2	-1.7	0.0	-0.7	-0.1	-0.1	-1.2	0.3	-1.6	-0.2	-0.1	-0.1	0.9	-0.5	0.3	-0.8	-0.3	0.2
Leg predicted mass (left)	0.2	0.9	8.7	0.3	0.5	0.7	2.9	-1.5	-0.3	0.7	0.4	0.6	1.5	0.9	-0.4	0.4	-0.5	0.7	0.7	-1.2	0.4	1.1	0.5	0.0	0.9
Had other major operations	0.2	0.3	1.7	-0.8	-0.3	-0.2	-0.6	-0.0	0.8	-0.1	-0.4	-0.5	-0.4	-0.9	-0.2	-0.0	-0.6	-0.5	-0.2	1.3	-0.2	-0.9	0.3	0.5	-0.6
Mouth/teeth dental problems	0.2	0.3	3.6	0.5	0.4	0.4	1.9	0.4	-0.6	0.4	0.4	0.5	0.1	0.1	0.8	-0.0	-0.2	-0.0	0.3	-0.6	0.3	0.2	0.6	0.4	-0.1
Weight	0.2	1.1	6.6	-1.0	-0.9	-0.5	2.0	-2.6	-1.3	-0.6	-1.1	-0.8	0.3	-1.0	-0.0	-1.4	-0.6	-0.6	-0.6	-0.7	-1.2	0.5	0.0	-1.0	0.8
Hip circumference	0.2	0.8	4.5	-0.4	-0.2	-0.1	2.1	-1.8	-1.8	-0.1	-0.6	-0.9	0.8	-0.9	0.6	-0.5	-1.0	0.0	-0.1	0.7	-0.6	0.8	0.8	0.6	0.1
Lung cancer (father)	0.2	0.2	1.3	-0.8	0.4	0.3	-0.2	0.9	-0.6	0.3	0.2	-0.5	0.8	0.1	0.3	-0.0	-0.4	0.2	0.3	1.1	-0.1	-0.4	-0.2	0.0	-0.6
Standing height	0.2	2.2	12.3	1.1	-1.5	-1.4	1.1	-3.2	1.1	-1.5	-1.0	-1.5	0.7	0.4	-0.6	0.6	-0.7	-1.3	-1.3	-3.5	-1.6	0.3	1.7	-1.8	1.4
Arm fat-free mass (right)	0.2	1.2	12.0	0.9	0.2	0.4	3.5	-2.4	0.2	0.4	0.1	0.0	1.4	0.4	-0.7	0.5	-0.2	0.2	0.4	-1.2	0.0	1.6	0.4	0.3	1.3
Arm predicted mass (right)	0.2	1.3	11.5	1.1	0.1	0.3	3.4	-2.3	0.0	0.3	0.0	-0.2	1.6	0.5	-0.6	0.2	0.1	0.1	0.3	-1.4	-0.3	1.8	0.0	-0.0	1.6
Family relationship satisfaction	0.2	0.3	1.2	-0.3	-0.2	-0.2	-0.0	0.9	-1.1	-0.3	-0.3	0.4	0.4	-0.5	-0.5	-0.4	0.7	0.4	-0.3	0.9	-0.1	-0.2	-0.7	0.5	0.6
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	0.9	0.3	-0.2	-0.3	0.4	-0.3	-0.9	-0.2	-0.2	-0.5	-0.2	-0.2	1.0	-0.8	-0.0	-0.4	-0.3	-0.6	-0.6	0.8	0.3	-0.1	0.3
Whole body fat-free mass	0.2	1.4	12.3	1.2	0.5	0.6	3.5	-1.9	-0.5	0.6	0.3	0.3	1.9	0.9	-0.3	0.7	-0.0	0.6	0.6	-1.4	0.2	1.9	0.3	0.4	1.5
Leg fat-free mass (right)	0.2	1.2	10.1	0.3	1.0	1.1	3.2	-1.2	-0.1	1.1	0.9	1.0	1.5	1.1	-0.6	0.7	-0.7	1.1	1.1	-0.6	1.0	1.2	0.8	0.6	0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	1.6	-0.6	-0.1	0.0	-0.3	-0.1	-0.9	0.0	-0.1	0.1	0.2	-0.5	0.4	-1.3	-0.3	0.2	0.0	1.0	-0.1	-0.2	-0.0	-0.4	-0.8
Whole body water mass	0.2	1.4	11.9	1.1	0.3	0.5	3.5	-2.0	-0.5	0.4	0.2	0.3	1.9	0.7	-0.2	0.6	-0.1	0.4	0.5	-1.5	0.2	1.9	0.2	0.3	1.6
Leg predicted mass (right)	0.2	1.2	9.9	0.2	1.0	1.1	3.1	-1.3	-0.1	1.1	0.9	1.0	1.4	1.0	-0.6	0.7	-0.7	1.1	1.1	-0.6	0.9	1.2	0.9	0.6	0.4
Medication: Blood pressure	0.2	0.4	1.8	0.0	-0.3	-0.6	-0.1	0.8	0.3	-0.4	-0.6	0.3	0.3	-0.2	-0.1	-0.2	-1.0	0.3	-0.6	-0.6	0.8	-0.6	1.3	0.3	-1.2
Basal metabolic rate	0.2	1.1	10.3	0.6	0.1	0.3	3.2	-2.1	-0.6	0.2	-0.1	0.0	1.6	0.4	-0.4	0.3	-0.3	0.3	0.3	-1.2	-0.1	1.7	0.3	0.1	1.3
Vascular/heart problems diagnosed by doctor	0.2	0.7	3.8	-1.3	0.2	0.5	-0.3	-0.6	-1.1	0.4	0.3	-0.6	0.8	-0.9	-1.7	0.1	-0.8	-0.4	0.4	2.0	-1.0	0.5	0.0	0.7	-0.1
Pain experienced in last month	0.2	0.3	0.9	0.6	-0.2	-0.1	0.3	1.0	-0.6	-0.1	-0.1	-0.4	-0.6	-0.5	0.7	-0.7	0.8	-0.5	-0.1	0.2	-0.7	0.7	-0.6	0.1	0.5
Basal cell carcinoma (self-reported)	0.2	0.3	1.3	-1.1	-0.2	-0.2	0.2	-1.1	0.6	-0.1	-0.4	-0.4	-0.2	0.3	0.0	0.2	-0.6	-0.2	-0.2	-0.3	-0.4	-0.9	1.0	-0.6	0.4
Alzheimer’s Disease (including proxy)	0.1	0.2	1.3	-0.2	-0.5	-0.3	-1.0	-0.1	0.1	-0.2	-0.1	0.1	-0.0	-0.6	1.1	-0.6	0.6	-0.3	-0.3	0.0	-0.2	0.1	-0.7	-0.4	-0.0
Hypothyroidism (self reported)	0.1	0.3	1.6	0.3	0.2	0.0	0.1	1.3	-0.3	0.1	0.1	-0.3	-0.8	-0.1	-1.0	-0.2	-0.2	0.5	0.2	0.7	-0.7	0.4	0.3	0.8	-0.0
Hair Pigment	0.1	2.2	7.1	1.7	-2.2	-2.7	-0.8	-0.4	1.0	-2.4	-2.4	-2.1	-1.3	-1.2	1.1	0.2	0.1	-1.6	-2.4	-1.6	-1.0	0.4	-0.1	-0.8	0.8
Mouth/teeth dental problems: Dentures	0.1	0.2	1.8	0.2	-0.2	-0.3	-0.2	-0.7	1.4	-0.3	-0.3	-0.8	0.6	-0.1	-0.6	0.9	-0.3	-0.2	-0.2	0.2	-0.0	-0.3	0.5	-0.0	0.3
Neck or shoulder pain in last month	0.1	0.1	1.1	0.1	-0.3	-0.4	-0.4	0.1	0.0	-0.4	-0.2	-0.3	0.3	-0.2	-1.1	-0.2	-0.2	0.3	-0.3	0.5	-0.3	-0.4	0.4	0.2	0.2

Hub : Genes

SCUBE2

Models

Trait associations