[Hub]/) : Traits : Heel T-Score : ← →

chr12:55,601,472-57,872,720

Best TWAS P=3.1e-12 · Best GWAS P=4.73e-12 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Brain Cerebellum	RBMS2	0.25	0.05	lasso	5	0.14	4.6e-05	6.4	6.6	3.4e-11	0.65	0.04	0.41	FALSE
2	GTEx	Brain Cerebellum	IL23A	0.21	0.02	lasso	4	0.06	6.3e-03	6.4	-6.1	1.3e-09	-0.61	0.04	0.24	FALSE
3	GTEx	Colon Sigmoid	HSD17B6	0.11	0.08	enet	12	0.08	6.9e-04	6.7	7.0	3.3e-12	0.90	0.02	0.89	FALSE
4	GTEx	Esophagus Gastroesophageal Junction	WIBG	0.16	0.02	lasso	5	0.04	1.9e-02	-3.7	-5.6	1.8e-08	0.01	0.02	0.69	FALSE
5	GTEx	Muscle Skeletal	RAB5B	0.29	0.32	lasso	4	0.33	1.3e-33	5.2	-5.4	6.0e-08	0.02	0.10	0.89	FALSE
6	GTEx	Muscle Skeletal	AC034102.1	0.28	0.31	lasso	4	0.31	2.3e-31	5.3	-5.4	5.9e-08	0.02	0.10	0.90	FALSE
7	GTEx	Testis	BAZ2A	0.42	0.45	lasso	4	0.44	1.9e-21	6.2	6.2	5.9e-10	0.81	0.57	0.43	FALSE
8	METSIM	Adipose	NACA	0.05	0.05	lasso	6	0.04	3.1e-07	6.9	7.0	3.1e-12	0.97	0.01	0.99	TRUE
9	NTR	Blood	NACA	0.01	0.01	lasso	2	0.01	2.4e-03	5.7	-5.9	3.4e-09	-0.83	0.06	0.88	FALSE
10	NTR	Blood	NACA2	0.02	0.02	blup	328	0.02	8.9e-08	5.7	-6.3	3.9e-10	-0.76	0.31	0.69	FALSE
11	NTR	Blood	PRIM1	0.09	0.11	lasso	9	0.11	8.4e-34	5.7	5.9	3.7e-09	0.78	0.87	0.13	FALSE
12	YFS	Blood	BAZ2A	0.04	0.04	lasso	4	0.04	1.8e-13	6.1	6.3	2.5e-10	0.93	0.07	0.93	FALSE
13	YFS	Blood	RBMS2	0.47	0.26	enet	59	0.48	2.0e-183	6.1	5.3	1.4e-07	0.62	0.54	0.46	FALSE
14	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	RAB5B	0.07	0.00	blup	33	0.03	7.0e-03	-3.9	5.8	8.0e-09	0.01	0.01	0.34	FALSE
15	The Cancer Genome Atlas	Brain Lower Grade Glioma	ERBB3	0.07	0.02	blup	29	0.05	2.1e-06	5.9	5.8	9.2e-09	0.02	0.00	1.00	FALSE
16	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	RAB5B	0.05	0.02	blup	33	0.03	5.2e-03	-3.7	5.4	6.8e-08	0.01	0.01	0.34	FALSE
17	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	ESYT1	0.16	0.02	blup	33	0.05	5.5e-03	-2.8	5.9	4.1e-09	-0.04	0.01	0.67	TRUE
18	The Cancer Genome Atlas	Prostate Adenocarcinoma	NACA	0.02	0.02	blup	26	0.02	1.8e-03	6.9	6.7	1.7e-11	0.92	0.01	0.88	FALSE
19	The Cancer Genome Atlas	Soft Tissue Sarcoma	BAZ2A	0.04	0.05	blup	42	0.04	2.9e-03	5.6	-5.8	5.4e-09	-0.80	0.02	0.54	FALSE
20	The Cancer Genome Atlas	Thyroid Carcinoma	RAB5B	0.11	0.03	blup	33	0.08	7.0e-08	-3.7	5.9	4.5e-09	-0.01	0.34	0.55	FALSE