[Hub]/) : Traits : Heel T-Score : ← →

chr15:83,167,559-85,870,518

Best TWAS P=3.63e-12 · Best GWAS P=1.3e-35 conditioned to 1.29e-32

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous WHAMM 0.46 0.45 lasso 3 0.47 2.7e-42 5.1 -5.4 6.7e-08 0.13 0.00 1.00 FALSE
2 GTEx Adipose Subcutaneous RN7SL417P 0.07 0.06 lasso 7 0.05 1.3e-04 -4.7 -5.2 2.5e-07 -0.02 0.06 0.84 FALSE
3 GTEx Adipose Visceral Omentum RP11-182J1.14 0.17 0.05 enet 18 0.08 6.9e-05 -4.6 -5.3 1.0e-07 0.00 0.09 0.83 FALSE
4 GTEx Brain Cerebellum UBE2Q2P1 0.30 0.01 enet 35 0.06 7.5e-03 3.5 -7.0 3.6e-12 -0.01 0.14 0.06 TRUE
5 GTEx Brain Cerebellum CSPG4P11 0.28 0.23 lasso 5 0.28 9.0e-09 -4.7 -5.2 1.6e-07 -0.02 0.53 0.43 FALSE
6 GTEx Breast Mammary Tissue RN7SL417P 0.12 0.00 enet 13 0.00 5.6e-01 4.1 -5.3 1.1e-07 0.03 0.04 0.20 FALSE
7 GTEx Colon Sigmoid RN7SL417P 0.17 0.06 lasso 4 0.12 6.1e-05 -4.6 -5.2 2.2e-07 -0.01 0.05 0.76 FALSE
8 GTEx Colon Sigmoid RP11-182J1.16 0.28 0.01 enet 32 0.08 1.3e-03 -4.8 5.4 8.1e-08 0.00 0.23 0.17 FALSE
9 GTEx Esophagus Gastroesophageal Junction RP11-182J1.14 0.16 0.16 enet 16 0.17 1.1e-06 -4.4 -5.2 2.3e-07 0.01 0.11 0.84 FALSE
10 GTEx Lung ZSCAN2 0.09 0.00 lasso 4 0.01 7.6e-02 4.5 -5.7 1.3e-08 -0.02 0.15 0.04 FALSE
11 The Cancer Genome Atlas Bladder Urothelial Carcinoma WHAMM 0.09 0.05 blup 55 0.06 1.4e-05 5.1 -5.9 3.9e-09 0.12 0.00 1.00 TRUE
12 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma WHAMM 0.10 0.11 enet 4 0.11 5.1e-07 5.1 -5.3 1.3e-07 0.12 0.00 1.00 FALSE
13 The Cancer Genome Atlas Liver Hepatocellular Carcinoma WHAMM 0.14 0.05 enet 11 0.08 1.0e-04 5.1 -5.6 2.2e-08 0.09 0.00 0.98 FALSE
14 The Cancer Genome Atlas Lung Squamous Cell Carcinoma HOMER2 0.04 0.00 blup 71 0.02 6.6e-03 5.1 5.3 8.8e-08 -0.16 0.00 0.72 FALSE