[Hub]/) : Traits : Heel T-Score : ← →

chr3:155,544,380-157,935,626

Best TWAS P=2.61e-78 · Best GWAS P=3.26e-67 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	LEKR1	0.22	0.08	lasso	17	0.16	2.2e-18	-16.857	11.9	2.0e-32	-0.71	0.12	0.88	FALSE
2	CommonMind	Brain Pre-frontal Cortex	SSR3	0.08	0.01	bslmm	403	0.05	1.0e-06	0.923	9.1	1.3e-19	-0.32	0.19	0.08	TRUE
3	GTEx	Adipose Subcutaneous	LINC00886	0.42	0.24	enet	28	0.38	1.7e-32	-12.461	-10.2	1.4e-24	0.52	1.00	0.00	FALSE
4	GTEx	Adipose Visceral Omentum	LINC00886	0.31	0.03	enet	36	0.15	4.0e-08	-12.461	-8.9	6.3e-19	0.37	0.72	0.10	TRUE
5	GTEx	Artery Aorta	LINC00886	0.40	0.24	lasso	9	0.22	2.7e-12	-12.461	-12.1	1.9e-33	0.55	0.98	0.02	FALSE
6	GTEx	Artery Aorta	RP11-305K5.1	0.14	0.08	lasso	9	0.06	2.7e-04	1.101	-5.7	1.0e-08	0.13	0.29	0.16	FALSE
7	GTEx	Artery Tibial	TIPARP	0.13	0.02	enet	17	0.05	8.2e-05	-15.649	-17.3	2.0e-67	0.70	0.04	0.94	FALSE
8	GTEx	Artery Tibial	LINC00886	0.43	0.26	enet	59	0.42	4.2e-35	-12.461	-16.0	1.4e-57	0.68	0.39	0.61	FALSE
9	GTEx	Breast Mammary Tissue (Male)	LINC00886	0.17	0.03	enet	4	0.04	4.4e-02	-12.461	-9.2	5.0e-20	0.59	0.06	0.24	FALSE
10	GTEx	Cells Transformed fibroblasts	SSR3	0.08	0.01	lasso	6	0.02	2.1e-02	-6.229	6.9	4.8e-12	-0.04	0.24	0.03	FALSE
11	GTEx	Cells Transformed fibroblasts	LINC00886	0.11	0.01	lasso	7	0.01	4.1e-02	8.535	7.7	2.0e-14	-0.03	0.14	0.04	FALSE
12	GTEx	Colon Sigmoid	LINC00886	0.58	0.28	enet	26	0.40	1.7e-15	-1.717	-6.2	4.7e-10	0.47	0.97	0.03	FALSE
13	GTEx	Colon Transverse	SSR3	0.11	0.00	enet	22	0.01	9.2e-02	1.022	7.3	2.9e-13	-0.33	0.04	0.29	FALSE
14	GTEx	Colon Transverse	METTL15P1	0.26	0.00	lasso	5	-0.01	7.8e-01	-0.059	-6.0	1.9e-09	0.09	0.05	0.11	TRUE
15	GTEx	Colon Transverse	LINC00886	0.41	0.24	lasso	14	0.24	1.7e-11	-12.461	-9.1	8.2e-20	0.55	0.98	0.02	FALSE
16	GTEx	Esophagus Gastroesophageal Junction	LINC00886	0.40	0.31	enet	25	0.34	4.8e-13	-13.488	-9.0	2.2e-19	0.48	0.99	0.01	FALSE
17	GTEx	Esophagus Muscularis	METTL15P1	0.10	0.03	lasso	2	0.02	1.8e-02	-13.822	-14.0	1.6e-44	0.61	0.29	0.50	FALSE
18	GTEx	Esophagus Muscularis	LINC00886	0.46	0.29	lasso	6	0.43	4.1e-28	-12.461	-5.8	6.5e-09	0.37	1.00	0.00	FALSE
19	GTEx	Heart Atrial Appendage	LINC00886	0.33	0.04	lasso	11	0.03	2.0e-02	-3.471	-8.0	1.4e-15	0.56	0.28	0.47	FALSE
20	GTEx	Heart Left Ventricle	LINC00886	0.25	0.08	lasso	10	0.07	1.5e-04	-12.873	-9.3	8.5e-21	0.45	0.45	0.10	FALSE
21	GTEx	Heart Left Ventricle	TIPARP-AS1	0.20	0.11	enet	17	0.09	1.8e-05	1.479	6.7	1.9e-11	0.05	0.51	0.02	FALSE
22	GTEx	Lung	LINC00886	0.19	0.07	enet	21	0.13	2.5e-10	-12.461	-9.3	1.9e-20	0.50	0.92	0.07	FALSE
23	GTEx	Muscle Skeletal	LINC00886	0.23	0.10	enet	29	0.14	1.9e-13	-12.461	-6.2	5.9e-10	0.43	1.00	0.00	FALSE
24	GTEx	Nerve Tibial	LINC00886	0.30	0.14	lasso	16	0.16	8.4e-12	-12.461	-9.7	2.6e-22	0.54	0.92	0.08	FALSE
25	GTEx	Pancreas	LINC00886	0.32	0.23	enet	25	0.26	3.1e-11	-12.461	-12.0	4.6e-33	0.56	0.92	0.08	FALSE
26	GTEx	Prostate	LINC00886	0.40	0.18	lasso	13	0.16	8.0e-05	-3.471	-6.0	1.5e-09	0.52	0.14	0.21	TRUE
27	GTEx	Spleen	LINC00886	0.46	0.05	enet	21	0.12	7.4e-04	-2.492	-5.7	1.5e-08	0.46	0.09	0.30	FALSE
28	GTEx	Stomach	LINC00886	0.44	0.09	enet	42	0.27	1.8e-13	-13.488	-7.5	5.5e-14	0.49	0.98	0.02	TRUE
29	GTEx	Testis	LINC00886	0.39	0.24	lasso	9	0.21	1.5e-09	-12.461	-9.6	6.4e-22	0.36	0.99	0.00	FALSE
30	GTEx	Uterus	LINC00886	0.30	0.13	lasso	5	0.14	1.1e-03	-12.461	-7.8	7.1e-15	0.24	0.08	0.09	FALSE
31	METSIM	Adipose	CCNL1	0.03	0.01	blup	432	0.02	9.6e-04	-6.326	-10.4	4.1e-25	0.22	0.90	0.01	FALSE
32	METSIM	Adipose	LEKR1	0.09	0.09	lasso	3	0.09	1.7e-13	-16.857	16.7	9.1e-63	-0.85	0.36	0.64	FALSE
33	METSIM	Adipose	LINC00886	0.39	0.22	bslmm	466	0.26	3.3e-39	-11.631	-6.5	7.9e-11	0.39	1.00	0.00	FALSE
34	METSIM	Adipose	TIPARP	0.07	0.08	lasso	4	0.08	6.3e-12	-15.918	-15.9	7.8e-57	0.09	1.00	0.00	TRUE
35	METSIM	Adipose	VEPH1	0.05	0.02	blup	510	0.02	3.9e-04	2.140	-8.5	2.6e-17	0.22	0.78	0.04	TRUE
36	NTR	Blood	SSR3	0.02	0.01	lasso	3	0.01	2.5e-05	-5.198	7.3	3.7e-13	-0.11	0.93	0.00	TRUE
37	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	LEKR1	0.10	0.14	lasso	6	0.12	1.8e-10	-16.857	17.1	1.2e-65	-0.85	0.18	0.82	FALSE
38	The Cancer Genome Atlas	Breast Invasive Carcinoma	LEKR1	0.13	0.16	lasso	5	0.15	3.6e-30	-17.106	16.8	3.8e-63	-0.85	0.09	0.91	FALSE
39	The Cancer Genome Atlas	Breast Invasive Carcinoma	LOC100287227	0.05	0.01	blup	47	0.02	1.7e-04	-10.866	6.3	3.0e-10	-0.40	0.00	0.96	FALSE
40	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	LEKR1	0.18	0.12	enet	8	0.10	9.2e-06	-17.106	18.1	6.0e-73	-0.90	0.02	0.97	FALSE
41	The Cancer Genome Atlas	Colon Adenocarcinoma	LEKR1	0.16	0.12	lasso	2	0.09	5.2e-06	-17.106	16.9	3.6e-64	-0.85	0.12	0.87	FALSE
42	The Cancer Genome Atlas	Esophageal Carcinoma	LEKR1	0.25	0.08	blup	112	0.18	2.0e-06	-16.790	16.8	1.2e-63	-0.72	0.03	0.88	FALSE
43	The Cancer Genome Atlas	Esophageal Carcinoma	LOC100287227	0.14	0.04	lasso	5	0.02	5.7e-02	-10.336	10.3	4.6e-25	-0.24	0.01	0.63	FALSE
44	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	LEKR1	0.09	0.10	lasso	3	0.09	4.4e-10	-16.790	17.6	3.0e-69	-0.87	0.32	0.68	FALSE
45	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	LEKR1	0.22	0.18	enet	21	0.22	2.1e-24	-17.321	15.7	2.0e-55	-0.86	0.00	1.00	FALSE
46	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	LEKR1	0.16	0.13	lasso	5	0.13	8.4e-08	-17.106	17.6	4.8e-69	-0.92	0.01	0.99	FALSE
47	The Cancer Genome Atlas	Brain Lower Grade Glioma	LEKR1	0.06	0.01	blup	112	0.04	4.6e-05	-17.321	10.4	3.2e-25	-0.80	0.00	0.98	FALSE
48	The Cancer Genome Atlas	Lung Adenocarcinoma	LEKR1	0.09	0.12	lasso	1	0.11	1.2e-12	-17.106	17.1	1.3e-65	-0.85	0.16	0.84	FALSE
49	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	LEKR1	0.12	0.07	blup	114	0.08	2.6e-09	-17.225	14.5	2.4e-47	-0.87	0.02	0.98	FALSE
50	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	LEKR1	0.23	0.27	lasso	2	0.26	1.7e-17	-16.790	16.8	5.4e-63	-0.84	0.29	0.71	FALSE
51	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	LEKR1	0.14	0.15	lasso	1	0.15	9.8e-07	-17.106	17.1	1.3e-65	-0.85	0.13	0.80	FALSE
52	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	LEKR1	0.27	0.07	blup	113	0.07	1.0e-03	-16.857	14.5	2.4e-47	-0.78	0.02	0.92	FALSE
53	The Cancer Genome Atlas	Prostate Adenocarcinoma	LEKR1	0.20	0.19	lasso	5	0.19	2.6e-19	-17.106	16.9	2.1e-64	-0.85	0.22	0.78	FALSE
54	The Cancer Genome Atlas	Rectum Adenocarcinoma	LEKR1	0.40	0.25	lasso	2	0.26	9.1e-07	-17.225	17.1	7.3e-66	-0.97	0.00	0.99	FALSE
55	The Cancer Genome Atlas	Soft Tissue Sarcoma	LEKR1	0.15	0.04	lasso	6	0.09	6.9e-06	-17.106	18.7	2.6e-78	-0.84	0.03	0.97	TRUE
56	The Cancer Genome Atlas	Skin Cutaneous Melanoma	LOC100287227	0.15	0.03	blup	47	0.00	2.9e-01	-3.025	6.6	4.1e-11	-0.36	0.01	0.21	TRUE
57	The Cancer Genome Atlas	Stomach Adenocarcinoma	LEKR1	0.06	0.07	lasso	3	0.07	1.1e-05	-17.225	18.0	1.9e-72	-0.95	0.01	0.99	FALSE
58	The Cancer Genome Atlas	Stomach Adenocarcinoma	LOC100287227	0.07	0.01	blup	47	0.02	9.8e-03	-2.508	6.4	2.0e-10	-0.20	0.01	0.57	FALSE
59	The Cancer Genome Atlas	Testicular Germ Cell Tumors	LEKR1	0.12	0.03	blup	114	0.03	2.5e-02	-13.822	12.1	8.0e-34	-0.58	0.04	0.19	FALSE
60	The Cancer Genome Atlas	Thyroid Carcinoma	CCNL1	0.06	0.02	lasso	3	0.04	6.9e-05	-4.845	7.5	8.5e-14	-0.05	0.01	0.98	FALSE
61	The Cancer Genome Atlas	Thyroid Carcinoma	LEKR1	0.24	0.33	lasso	8	0.37	9.5e-38	-17.225	18.1	1.9e-73	-0.95	0.01	0.99	FALSE
62	The Cancer Genome Atlas	Thyroid Carcinoma	LOC100287227	0.11	0.07	blup	47	0.09	3.1e-09	1.479	6.0	2.0e-09	-0.31	0.09	0.90	FALSE
63	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	LEKR1	0.21	0.14	lasso	4	0.10	8.6e-04	-17.106	17.1	1.3e-65	-0.85	0.02	0.79	FALSE