[Hub]/) : Traits : Irritable Bowel Disease (IBD) :

chr16:49,403,920-51,535,063

Best TWAS P=1.28e-33 · Best GWAS P=1.84e-45 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Hypothalamus CYLD 0.38 0.13 enet 36 0.15 2.7e-04 -8.22 -6.2 6.9e-10 -0.28 0.14 0.09 TRUE
2 GTEx Colon Transverse NKD1 0.22 0.00 enet 42 0.05 2.5e-03 -0.51 -5.8 6.2e-09 -0.17 0.21 0.11 TRUE
3 GTEx Esophagus Mucosa CYLD 0.13 0.06 enet 10 0.06 7.0e-05 -8.73 11.9 1.5e-32 0.72 0.06 0.93 TRUE
4 GTEx Esophagus Mucosa NOD2 0.19 0.14 lasso 7 0.15 4.1e-10 -8.31 8.9 7.0e-19 0.46 0.99 0.01 FALSE
5 GTEx Nerve Tibial CYLD 0.10 0.00 lasso 6 0.00 1.7e-01 6.95 6.7 1.9e-11 0.37 0.10 0.05 TRUE
6 GTEx Skin Not Sun Exposed Suprapubic NOD2 0.15 0.06 lasso 4 0.02 1.9e-02 -8.29 8.6 6.7e-18 0.46 0.54 0.24 TRUE
7 GTEx Testis NKD1 0.24 0.13 lasso 4 0.14 8.1e-07 6.15 7.5 4.5e-14 0.10 0.76 0.01 TRUE
8 GTEx Testis HEATR3 0.47 0.37 enet 33 0.38 4.5e-18 3.56 -5.2 2.0e-07 -0.10 1.00 0.00 TRUE
9 GTEx Whole Blood BRD7 0.16 0.12 enet 9 0.12 4.2e-11 -6.28 -6.2 5.6e-10 0.00 1.00 0.00 TRUE
10 METSIM Adipose ADCY7 0.04 0.00 enet 22 0.01 1.7e-02 1.49 -6.9 4.6e-12 -0.03 0.20 0.04 TRUE
11 METSIM Adipose BRD7 0.06 0.05 lasso 6 0.05 1.1e-07 -6.28 -6.2 6.4e-10 0.01 1.00 0.00 TRUE
12 NTR Blood ADCY7 0.07 0.06 enet 17 0.07 2.0e-20 -6.30 -6.1 1.3e-09 0.01 1.00 0.00 FALSE
13 YFS Blood PAPD5 0.03 0.01 enet 13 0.02 1.4e-07 -6.41 -6.2 5.7e-10 0.02 0.96 0.00 FALSE
14 The Cancer Genome Atlas Brain Lower Grade Glioma CYLD 0.03 0.03 enet 7 0.02 9.3e-04 -8.56 6.0 1.7e-09 0.29 0.26 0.04 TRUE
15 The Cancer Genome Atlas Lung Adenocarcinoma CYLD 0.03 0.00 blup 69 0.02 3.8e-03 -8.73 11.9 1.5e-32 0.60 0.11 0.66 TRUE
16 The Cancer Genome Atlas Lung Adenocarcinoma NOD2 0.07 0.01 lasso 4 0.02 1.1e-03 14.15 12.1 1.3e-33 0.78 0.00 0.91 TRUE