TWAS hub - ASB8

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Visceral Omentum	0.1040	0.0460	3.2e-03	-0.003	NA	-0.005	NA	-0.005	4.8e-01	NA	9.9e-01	NA	6.8e-01
2	GTEx	Brain Caudate basal ganglia	0.1770	0.0730	4.0e-03	0.017	NA	0.032	NA	0.044	1.0e-01	NA	4.3e-02	NA	2.1e-02
3	GTEx	Brain Cortex	0.2800	0.0960	3.8e-04	0.194	NA	0.171	NA	0.200	4.7e-06	NA	1.8e-05	NA	3.3e-06
4	GTEx	Brain Frontal Cortex BA9	0.2430	0.0930	1.5e-03	0.155	NA	0.033	NA	0.068	6.6e-05	NA	4.8e-02	NA	7.1e-03
5	GTEx	Brain Nucleus accumbens basal ganglia	0.2040	0.0800	2.2e-03	0.040	NA	0.015	NA	0.024	3.2e-02	NA	1.3e-01	NA	7.7e-02
6	GTEx	Breast Mammary Tissue	0.1680	0.0680	2.9e-03	0.015	NA	0.025	NA	0.020	5.1e-02	NA	1.9e-02	NA	3.0e-02
7	GTEx	Breast Mammary Tissue (Female)	0.2655	0.1038	6.6e-03	-0.001	NA	-0.010	NA	-0.004	3.3e-01	NA	9.2e-01	NA	4.4e-01
8	GTEx	Nerve Tibial	0.0867	0.0346	1.1e-03	0.082	NA	0.042	NA	0.067	2.1e-06	NA	5.5e-04	NA	1.8e-05
9	GTEx	Testis	0.1680	0.0650	7.0e-04	0.147	NA	0.115	NA	0.133	4.6e-07	NA	8.6e-06	NA	1.8e-06
10	GTEx	Thyroid	0.0900	0.0410	2.3e-03	0.002	NA	0.014	NA	0.006	2.2e-01	NA	2.8e-02	NA	1.0e-01
11	METSIM	Adipose	0.0307	0.0158	1.9e-02	0.002	0.006	0.000	0.006	0.001	1.6e-01	4.1e-02	2.9e-01	3.8e-02	2.1e-01
12	YFS	Blood	0.0507	0.0149	1.1e-12	0.050	0.046	0.051	0.048	0.047	5.4e-16	9.3e-15	3.6e-16	1.7e-15	4.7e-15
13	TCGA	Head and Neck Squamous Cell Carcinoma	0.0673	0.0532	6.1e-03	0.019	0.016	0.022	NA	0.008	2.9e-03	5.3e-03	1.3e-03	NA	4.2e-02
14	TCGA	Kidney Renal Clear Cell Carcinoma	0.0431	0.0257	4.9e-04	0.027	0.027	0.023	NA	0.022	4.8e-04	4.1e-04	1.2e-03	NA	1.6e-03
15	TCGA	Brain Lower Grade Glioma	0.0810	0.0431	1.2e-05	0.015	0.037	0.035	NA	0.034	7.0e-03	3.9e-05	7.5e-05	NA	8.2e-05
16	TCGA	Lung Adenocarcinoma	0.0337	0.0215	5.8e-03	0.001	0.012	0.005	NA	0.005	2.4e-01	1.2e-02	7.9e-02	NA	7.9e-02
17	TCGA	Ovarian Serous Cystadenocarcinoma	0.0680	0.0450	9.5e-03	0.047	0.022	0.032	NA	0.040	3.8e-04	1.1e-02	3.0e-03	NA	1.0e-03
18	TCGA	Stomach Adenocarcinoma	0.0870	0.0450	4.1e-04	0.007	0.036	0.026	NA	0.018	9.2e-02	1.1e-03	5.4e-03	NA	1.7e-02
19	TCGA	Thyroid Carcinoma	0.0400	0.0240	6.1e-04	0.032	0.030	0.024	NA	0.035	4.1e-04	5.9e-04	1.8e-03	NA	2.3e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19
Impedance of arm (right)	8.5	39.6	74.8	7.9	6.8	8.6	8.2	7.9	2.5	0.5	8.1	8.5	4.3	7.5	3.0	2.8	8.3	7.3	3.2	-2.2	-2.0	7.9
Impedance of leg (right)	6.8	32.9	76.8	8.8	6.2	7.4	6.9	5.9	4.7	3.6	6.6	8.3	4.6	8.0	0.7	-0.2	5.7	4.6	-0.7	-4.9	-3.9	6.7
Tinnitus: Yes, now most or all of the time	6.8	7.9	15.6	-3.0	-2.8	-3.9	-3.5	-4.0	-1.6	-1.1	-3.7	-3.2	-2.6	-3.6	-1.1	-1.2	-3.5	-3.0	-0.7	1.9	1.7	-3.5
Impedance of whole body	6.7	34.1	66.7	8.1	6.3	7.9	7.5	6.8	3.4	2.3	7.1	8.2	4.3	7.8	2.0	1.1	7.1	6.2	1.1	-3.3	-2.5	7.1
Impedance of arm (left)	6.6	30.8	58.8	6.9	5.8	7.6	7.2	7.0	2.3	0.8	7.0	7.7	3.6	6.8	2.8	2.3	7.4	6.8	2.7	-1.8	-1.5	6.9
Blood Red Count	6.2	59.6	116.9	-9.3	-6.9	-9.6	-8.5	-7.8	-8.7	-4.7	-8.5	-10.8	-6.8	-9.2	4.8	2.2	-6.1	-6.4	5.0	10.7	6.9	-7.9
Cardiovascular Disease	5.5	18.1	31.1	5.2	5.0	5.4	5.3	5.6	2.5	0.6	5.2	5.2	4.7	5.3	0.3	1.5	5.2	4.7	0.9	-2.5	-2.4	5.2
Medication: Simvastatin	5.5	8.1	15.8	4.0	2.6	3.7	3.5	2.8	3.0	2.1	3.2	3.7	3.4	3.4	-1.3	0.7	2.2	2.0	-1.1	-2.2	-3.0	3.4
High blood pressure (mother)	5.1	7.1	13.6	3.6	3.4	3.3	3.3	2.6	2.5	-0.6	3.4	3.3	2.5	3.7	-0.3	1.8	3.1	3.0	0.9	-1.4	-0.9	2.8
Impedance of leg (left)	4.8	23.1	57.0	7.6	4.9	6.0	5.7	4.5	4.2	3.9	5.3	6.9	3.8	6.9	-0.2	-0.7	4.2	3.2	-1.7	-4.9	-3.8	5.5
Hand grip strength (left)	4.6	12.1	24.7	-5.0	-3.8	-4.3	-3.9	-4.7	-3.1	-0.8	-4.2	-4.9	-2.8	-4.0	-1.5	0.0	-4.2	-3.6	-0.8	3.0	1.6	-3.8
Systolic Blood Pressure	4.5	22.7	39.8	6.2	5.6	5.7	5.4	5.4	3.9	1.1	5.7	5.4	6.3	6.2	-0.3	4.3	5.4	5.4	1.9	-0.9	-2.3	5.3
Medication for cholesterol	4.5	6.8	11.9	-3.4	-2.9	-3.4	-3.1	-3.4	-2.3	0.3	-3.2	-3.4	-2.0	-3.1	0.6	-2.1	-3.0	-3.0	-0.4	1.8	1.5	-2.9
Hand grip strength (right)	4.2	11.5	23.4	-4.7	-3.0	-4.1	-3.6	-4.2	-3.9	-2.1	-4.2	-4.8	-3.1	-3.8	0.3	0.3	-3.4	-2.9	0.7	4.0	2.8	-3.6
Medication: Blood pressure	4.2	7.3	14.2	3.1	2.5	3.3	3.0	3.8	2.2	0.5	3.5	3.7	3.4	3.1	0.0	2.0	3.3	3.0	1.1	-1.0	-1.7	3.0
Bipolar Disorder (2011)	4.1	4.0	11.0	-2.5	-1.3	-1.8	-1.7	-1.4	-1.8	-3.3	-1.9	-1.9	-2.2	-3.3	1.8	0.0	-0.8	-0.6	1.8	2.4	2.4	-1.9
Knee pain experienced in last month	4.1	6.4	15.3	2.9	2.4	2.6	2.6	2.5	3.1	2.5	2.5	3.3	1.5	2.9	-1.9	-0.6	1.3	1.2	-2.0	-3.9	-3.2	2.7
High cholesterol (Self-reported)	4.1	7.3	12.2	3.5	2.5	3.2	3.2	2.3	2.3	2.4	2.9	3.5	3.0	3.5	-2.0	0.3	1.6	1.6	-1.9	-2.9	-3.3	3.1
Medication: Cholesterol lowering	4.0	6.3	11.5	3.2	2.0	3.3	2.8	2.6	2.5	1.7	2.8	3.1	3.4	3.0	-1.2	0.1	1.9	1.7	-1.4	-2.7	-2.9	2.7
Medication for cholesterol, blood pressure or diabetes	4.0	6.7	14.1	-3.2	-2.3	-3.3	-2.9	-3.3	-2.4	-1.1	-3.1	-3.4	-3.8	-3.0	0.3	-0.6	-2.9	-2.6	0.0	1.8	1.9	-2.7
Medication: Amlodipine	3.8	5.3	11.2	3.3	1.9	2.6	2.1	3.0	2.2	0.3	2.9	3.2	3.0	2.9	0.1	1.1	2.7	2.8	0.7	-1.1	-1.2	2.1
Illnesses of father: High blood pressure	3.7	4.5	8.9	2.4	2.8	2.3	2.1	2.7	1.9	-0.1	2.6	2.6	2.0	2.8	0.6	1.5	2.9	3.0	1.6	-0.1	0.0	1.9
Cholesterol lowering medication	3.6	5.3	15.4	3.9	1.9	3.0	2.8	2.8	1.9	1.2	2.8	2.9	1.6	2.7	-0.9	0.7	2.1	1.5	-0.5	-2.3	-2.4	2.8
Worry too long after embarrassment	3.4	5.7	12.9	2.7	2.9	2.9	2.6	3.4	1.7	0.1	2.8	3.3	2.2	3.6	1.2	0.6	3.1	2.8	1.3	-0.7	-0.7	2.5
Medication: Atenolol	3.3	4.1	8.5	1.6	1.7	2.4	2.3	2.8	-0.1	-0.5	2.7	2.5	1.7	2.1	1.5	2.2	2.9	2.8	2.3	0.4	0.1	2.1
Hypertension (Self-reported)	3.3	9.3	21.4	3.6	3.3	3.5	3.2	4.6	1.8	-0.8	3.6	3.6	3.2	3.0	1.3	1.9	4.6	4.5	1.9	-0.4	-0.4	3.0
Heel T-Score	3.1	24.5	46.5	-6.0	-5.3	-6.5	-6.4	-6.5	-2.5	-1.3	-6.2	-6.8	-3.1	-6.4	-1.9	0.7	-6.2	-5.7	-0.9	4.1	1.8	-6.0
High blood pressure	3.0	8.5	19.2	3.5	2.9	3.1	2.9	4.3	1.9	-0.7	3.4	3.4	3.3	3.0	1.2	2.2	4.4	4.4	2.0	0.0	-0.2	2.7
Leg pain on walking	3.0	3.8	10.0	2.9	2.2	1.9	2.0	2.6	2.4	1.0	1.9	3.2	1.6	2.7	0.1	0.6	1.8	2.0	-0.4	-1.4	-1.0	1.9
Illnesses of mother	2.9	3.6	7.8	-2.8	-2.5	-2.6	-2.4	-2.2	-1.5	0.4	-2.4	-2.1	-1.4	-1.7	-0.0	-1.3	-2.3	-2.1	-0.7	1.2	1.1	-2.2
Peak expiratory flow (PEF)	2.9	6.7	14.0	-3.7	-1.7	-3.0	-2.5	-3.7	-0.5	0.3	-3.5	-3.7	-2.3	-3.7	-1.7	0.1	-3.6	-2.8	-1.9	1.6	0.9	-2.5
Townsend deprivation index at recruitment	2.8	3.9	9.7	3.1	1.7	2.1	2.3	1.8	2.2	1.5	2.1	1.9	0.7	3.0	-1.4	0.6	0.9	0.9	-1.3	-2.4	-2.7	2.3
Heart disease (mother)	2.8	3.4	8.4	2.1	1.2	2.2	1.9	1.8	1.6	0.7	2.3	2.3	2.9	1.9	-1.6	2.5	1.4	1.5	-0.0	-0.8	-2.1	1.9
Trunk fat percentage	2.7	10.9	22.0	3.5	3.6	4.7	4.7	4.0	1.4	1.6	4.3	4.0	2.9	3.8	0.0	1.0	3.8	3.7	0.1	-2.7	-2.0	4.5
Basal cell carcinoma (self-reported)	2.7	3.2	10.1	-2.1	-0.2	-0.8	-1.1	0.6	-2.6	-2.4	-0.9	-1.3	-0.5	-0.7	3.2	-0.3	0.9	0.8	3.0	2.7	3.0	-1.3
Average weekly spirits intake	2.6	3.2	10.7	1.9	0.2	1.2	1.3	-0.2	2.2	1.0	1.2	1.6	2.8	1.6	-3.0	1.9	-0.8	-1.4	-1.5	-1.8	-3.3	1.5
Sitting height	2.6	18.6	55.2	3.4	4.6	4.6	4.0	4.8	1.8	-3.4	3.6	2.6	2.8	1.8	5.4	3.6	6.8	7.4	5.3	4.1	3.9	3.4
Vascular/heart problems diagnosed by doctor	2.6	7.2	15.8	-3.7	-2.6	-2.9	-2.5	-3.9	-2.0	0.8	-2.9	-3.3	-3.0	-2.9	-1.3	-1.6	-4.0	-4.0	-1.6	0.3	0.1	-2.3
Alcohol intake versus 10 years previously	2.5	3.7	10.1	0.3	1.3	1.8	1.6	2.1	0.6	-1.1	1.8	1.0	2.6	1.6	1.7	3.2	2.6	2.9	2.8	1.9	1.2	1.3
Mouth/teeth dental problems: Bleeding gums	2.5	3.2	6.2	1.1	2.5	2.2	2.2	2.2	-1.6	-0.9	2.2	1.6	1.6	2.4	1.7	-0.2	2.5	1.8	1.2	-0.7	-0.2	2.3
Heel bone mineral density (BMD) T-score, automated (left)	2.4	5.5	11.5	-2.6	-2.3	-3.1	-2.7	-3.4	-0.7	-0.9	-2.8	-3.3	-0.9	-3.3	-1.6	-0.0	-3.2	-3.0	-0.9	1.6	0.7	-2.6
Ever had bowel cancer screening	2.4	2.8	7.9	1.6	1.9	2.0	1.7	2.8	1.3	-0.8	2.1	1.9	0.9	0.7	0.9	1.6	2.3	2.3	1.8	-0.0	-0.4	1.7
Pain type(s) experienced in last month: Hip pain	2.4	3.0	8.6	-0.9	-1.5	-1.7	-1.5	-1.8	1.0	1.3	-1.4	-0.6	-0.0	-1.3	-2.9	-0.3	-2.8	-2.6	-2.8	-1.5	-1.9	-1.2
Rheumatoid Arthritis	2.3	3.1	8.9	0.9	-2.5	-1.4	-1.7	-2.5	0.8	1.3	-1.8	-1.0	-0.5	-1.2	-2.4	-1.7	-2.4	-2.4	-3.0	-0.7	-0.8	-1.5
Medication: Co-codamol	2.3	2.6	7.2	2.5	1.6	1.8	1.7	1.2	2.7	-0.6	1.8	1.5	1.5	2.0	-0.1	2.2	1.5	1.6	0.9	0.4	-0.5	1.7
Comparative body size at age 10	2.3	6.5	19.0	-2.6	-3.0	-2.9	-2.7	-3.8	-1.1	0.2	-2.7	-2.9	-1.1	-1.8	-2.8	-1.0	-4.2	-4.4	-1.9	-0.4	-1.4	-2.4
Number of children fathered	2.3	2.6	6.3	-1.6	-0.9	-1.8	-1.8	-2.2	-1.6	-0.0	-2.1	-2.0	-1.1	-2.0	0.5	-2.5	-1.7	-1.9	-0.9	0.2	1.2	-1.8
Commuting to job workplace: Public transport	2.3	2.7	5.7	2.4	1.7	1.9	1.8	2.2	1.0	1.4	1.7	2.3	0.8	2.4	-0.2	-0.6	1.7	1.5	-0.3	-2.0	-1.0	1.8
Smoking Status	2.2	5.2	17.7	-0.8	-1.5	-0.5	-0.6	-1.2	0.8	3.3	-0.0	0.3	-0.8	0.4	-3.7	-2.3	-2.6	-3.0	-4.2	-3.6	-4.1	-0.2
Lung FVC	2.2	11.1	23.9	-4.4	-4.1	-3.5	-3.5	-4.4	-2.0	-0.6	-3.7	-4.7	-2.1	-4.1	-2.7	2.0	-4.9	-4.4	-1.2	1.4	-0.3	-3.3
Number of live births	2.2	3.1	7.7	-2.8	-1.4	-1.9	-1.5	-1.8	-2.6	-0.6	-1.5	-2.1	-1.8	-2.7	1.4	-0.8	-1.3	-1.4	1.1	2.1	1.1	-1.3
Loud music exposure frequency	2.2	2.4	8.9	2.4	1.2	1.6	1.5	1.3	1.0	3.0	1.2	1.8	1.0	1.3	-0.4	-0.9	0.8	0.5	-1.5	-2.0	-1.8	1.7
Medication for pain relief, constipation, heartburn	2.2	3.7	9.5	-2.1	-1.6	-2.2	-2.4	-3.1	-0.1	0.7	-2.1	-2.5	-0.5	-1.8	-1.6	-0.8	-2.8	-3.0	-2.0	-0.0	-0.5	-2.1
Angina (self-reported)	2.2	2.9	7.2	2.7	1.8	1.7	1.4	2.3	2.4	0.7	1.6	2.4	1.7	2.1	0.2	0.4	1.8	1.8	0.3	-1.8	-0.5	1.2
Overall health rating	2.2	4.8	10.4	2.9	2.1	2.1	2.3	2.9	1.6	1.6	2.3	2.9	1.0	3.2	0.3	-2.0	2.5	2.2	-0.5	-3.2	-0.6	2.1
Number of self-reported non-cancer illnesses	2.2	3.8	8.1	2.8	2.8	2.0	2.3	2.2	2.1	0.4	2.3	2.6	1.3	2.3	-0.1	0.7	2.1	2.2	0.2	-1.5	-1.0	2.3
Guilty feelings	2.2	3.3	10.1	2.2	1.3	1.9	1.7	1.7	0.9	0.9	2.0	2.0	-0.0	3.1	-1.2	-1.2	1.3	0.6	-1.6	-3.2	-2.3	1.9
Supplements: Fish oil (including cod liver oil)	2.2	2.9	6.4	-1.8	-1.8	-2.3	-1.8	-2.5	0.2	-0.9	-2.2	-1.4	-1.5	-2.2	0.3	0.4	-1.9	-1.2	0.0	2.5	1.9	-2.1
Fasting Glucose	2.1	2.5	5.1	1.7	2.1	2.0	1.8	1.8	0.5	1.0	2.2	1.4	2.3	0.9	1.6	0.1	2.0	1.6	1.4	0.3	-0.7	1.9
Neuroticism	2.1	5.0	13.9	2.7	2.1	2.3	2.3	1.7	2.7	1.5	2.6	3.1	1.8	3.7	-0.8	-0.6	1.4	0.9	-1.3	-2.5	-2.8	2.6
Angina	2.1	2.8	6.8	2.6	1.9	1.8	1.5	2.4	2.1	0.6	1.7	2.3	1.5	2.0	0.4	0.5	1.9	1.8	0.5	-1.6	-0.4	1.3
Neuroticism (Nagel 2018)	2.0	4.7	13.3	2.8	2.1	2.3	2.2	1.8	3.4	0.5	2.6	3.1	2.1	3.6	-0.2	0.8	1.7	1.6	-0.5	-1.4	-2.0	2.4
HbA1C	2.0	2.2	9.7	1.0	1.5	1.5	1.3	1.4	-0.1	2.0	1.4	0.9	0.3	1.2	-1.0	-2.1	1.2	1.4	-2.3	-3.1	-0.6	1.0
Schizophrenia (2014)	2.0	4.5	9.9	-2.4	-3.0	-2.7	-2.5	-2.9	-0.4	0.8	-2.6	-2.3	-1.8	-2.3	-2.0	-0.1	-3.1	-1.9	-1.7	0.6	0.6	-2.6
Type 2 Diabetes (T2D) (2012)	2.0	2.3	5.5	0.7	1.8	1.7	1.8	2.0	-0.8	-0.1	1.8	1.3	0.4	2.0	1.7	-1.4	2.3	2.0	1.0	-1.2	0.6	1.5
Other serious medical condition/disability diagnosed by doctor	2.0	2.7	6.4	-0.4	-1.9	-2.0	-1.8	-1.8	0.8	0.6	-1.9	-1.4	-0.9	-1.4	-2.1	-1.2	-2.5	-2.3	-2.0	-1.2	-0.7	-1.8
Systolic blood pressure, automated reading	2.0	5.7	10.9	2.9	3.3	2.5	2.6	2.3	1.9	-0.8	2.8	2.5	3.2	2.2	0.5	2.9	2.9	3.0	1.8	0.7	-0.3	2.6
Breastfed as a baby	2.0	2.5	5.3	-1.9	-1.7	-1.8	-2.0	-2.3	-0.0	1.5	-1.4	-0.7	-1.0	-1.4	-1.8	-0.6	-2.3	-2.0	-2.0	-0.4	-0.4	-1.8
Headache pain in last month	2.0	3.5	9.8	2.1	2.5	1.2	1.6	2.0	1.6	-1.4	1.0	1.9	-1.2	1.6	3.1	-0.1	2.4	2.8	2.2	0.2	2.2	1.1
Blood Platelet Count	1.9	22.3	56.0	5.4	3.0	6.9	5.4	3.9	4.0	0.5	5.8	6.4	7.5	6.7	-2.0	3.3	3.6	3.6	-1.7	-3.9	-4.1	4.9
Medication for hormone replacement therapy	1.9	2.2	5.4	1.5	1.2	1.8	1.6	0.9	1.8	1.2	1.5	1.4	1.6	1.1	-1.6	1.7	0.4	0.2	-0.8	-1.8	-2.3	1.7
Alcohol usually taken with meals	1.9	3.1	6.3	-2.2	-1.5	-2.5	-2.5	-1.8	-0.8	0.6	-2.3	-2.3	-1.1	-2.5	-0.3	-1.8	-1.5	-1.4	-0.8	0.7	1.4	-2.5
Length of working week for main job	1.9	2.1	4.5	2.0	1.4	2.1	1.9	1.5	0.2	0.2	1.7	2.1	1.9	1.1	0.0	-1.0	1.9	1.4	0.1	-1.1	-0.5	1.9
Migraine (self-reported)	1.9	2.3	6.5	1.2	2.5	1.9	2.3	2.1	-0.3	-0.3	1.7	1.9	0.6	0.7	0.5	-0.5	2.0	1.5	0.3	-1.9	-0.4	2.1
Medication: Lisinopril	1.9	2.5	5.0	0.6	1.8	1.8	1.7	2.2	0.4	-1.6	1.9	1.5	1.9	1.3	0.5	1.8	2.1	2.2	1.7	0.3	0.2	1.6
Schizophrenia vs Biploar Disorder	1.8	2.3	13.0	-0.1	-1.4	-1.0	-0.7	-0.9	1.0	1.6	-0.4	-0.2	0.6	-0.2	-3.6	-0.3	-2.0	-1.5	-2.9	-2.0	-2.1	-0.5
Time employed in main current job	1.8	2.1	5.4	2.3	1.5	1.2	1.2	2.0	1.2	-1.4	1.4	1.6	-0.4	1.1	1.6	1.3	2.0	2.0	1.5	0.4	0.3	1.0
Happiness	1.8	2.2	9.0	-0.9	-0.3	-1.2	-1.1	-1.2	-1.0	-2.5	-1.4	-1.2	-2.6	-1.0	1.2	-0.1	0.2	0.6	1.1	1.9	3.0	-1.4
Type 2 Diabetes (T2D) (2018)	1.7	3.1	6.0	1.5	2.2	2.2	2.2	2.3	1.3	1.2	2.1	2.0	1.3	1.9	-0.8	-0.6	1.8	1.8	-1.1	-2.5	-1.4	2.1
Chronic bronchitis/emphysema (father)	1.7	2.0	5.8	-1.4	-1.2	-1.9	-1.6	-1.6	-2.3	-1.3	-1.5	-2.4	-1.0	-1.1	-0.3	0.1	-1.5	-1.8	0.5	0.8	0.5	-1.5
Body fat percentage	1.7	6.7	13.4	2.8	2.7	3.6	3.7	2.9	1.3	1.9	3.2	3.0	2.2	3.1	-0.7	0.2	2.4	2.2	-0.7	-3.0	-2.2	3.5
Commuting to job workplace: Car/motor vehicle	1.7	1.9	5.4	-1.4	-1.2	-1.3	-1.5	-1.4	-0.9	-0.9	-1.3	-2.0	-0.8	-2.1	1.1	1.2	-1.1	-0.9	1.3	2.3	1.1	-1.3
Ever had stillbirth, spontaneous miscarriage or termination	1.7	1.8	9.2	-3.0	-0.2	-1.1	-0.9	-1.2	-2.3	-1.3	-0.9	-1.4	0.2	-2.4	0.7	-0.4	-0.6	-0.3	0.6	1.3	1.3	-1.0
Average weekly beer plus cider intake	1.7	2.5	7.5	1.3	1.7	2.3	2.1	1.6	0.1	0.4	1.9	1.7	2.7	1.8	0.9	0.8	1.3	0.7	0.8	-0.8	-1.5	2.2
Unable to work because of sickness or disability	1.7	2.2	4.5	-0.6	-1.7	-1.8	-1.4	-2.0	-0.1	1.3	-1.7	-1.1	-1.2	-1.4	-1.6	-1.6	-2.1	-1.8	-2.0	-1.0	-0.2	-1.3
Heel bone mineral density (BMD) T-score, automated (right)	1.6	3.6	8.9	-2.0	-1.6	-2.7	-2.0	-3.0	0.1	-0.9	-2.2	-2.4	-0.3	-2.7	-1.8	0.1	-2.8	-2.5	-0.8	1.4	0.3	-2.0
Father’s age at death	1.6	2.2	4.1	-1.5	-1.7	-2.0	-1.8	-1.6	-1.2	-1.0	-1.8	-1.3	-1.8	-1.6	1.2	-0.3	-1.2	-0.8	0.2	1.4	2.0	-2.0
Eye problems/disorders: None of the above	1.6	1.9	9.7	-1.6	-0.5	-0.5	-0.6	-1.3	-0.8	-2.4	-0.7	-0.7	0.8	-0.4	0.8	3.1	-0.2	0.4	1.7	2.1	2.1	-0.9
Chest pain or discomfort	1.6	2.3	6.2	1.8	1.7	1.2	1.2	1.9	0.6	-0.3	1.4	2.3	0.3	2.3	1.5	-0.3	2.2	2.5	1.3	-0.9	1.2	0.9
Alzheimer’s Disease (in father)	1.5	1.7	10.1	-1.3	-0.7	-0.9	-0.8	-0.5	-1.6	-3.2	-1.5	-1.7	-0.7	-1.4	0.7	-0.1	-0.4	-0.2	1.1	0.8	1.9	-1.1
Diabetes (mother)	1.5	1.9	4.3	1.5	1.5	1.7	1.6	1.5	0.8	0.9	1.8	1.6	2.1	1.4	-0.3	1.3	1.5	1.4	0.3	-0.4	-1.2	1.6
Past tobacco smoking	1.5	2.8	10.4	-1.0	-1.1	-2.1	-1.8	-1.1	-1.4	-1.1	-2.0	-2.2	-0.6	-1.3	2.0	0.2	-0.3	0.3	1.9	2.4	3.2	-2.0
Noisy workplace	1.5	1.8	4.6	1.7	1.5	1.6	1.9	0.8	1.6	0.7	1.2	0.8	1.2	1.8	-0.9	-0.1	0.3	0.3	-1.4	-1.2	-2.1	1.9
Lung cancer (father)	1.5	1.8	4.4	1.2	1.0	1.4	1.3	1.7	0.6	-0.4	1.3	1.6	0.4	0.5	1.9	1.1	2.0	2.1	2.0	0.8	0.5	1.2
Medication: Paracetamol	1.5	2.6	5.0	1.7	1.4	1.6	2.1	2.1	0.0	-1.0	1.7	2.0	-0.1	1.8	1.7	0.5	2.2	2.1	2.0	0.0	0.6	1.9
Health satisfaction	1.5	1.9	5.8	1.7	1.7	1.1	1.4	1.5	0.2	1.1	1.3	1.7	0.3	1.7	-1.0	-1.5	1.4	1.0	-1.1	-2.4	-0.9	1.4
Shortness of breath walking on level ground	1.5	1.8	5.0	2.1	1.5	1.2	1.2	1.3	-0.2	0.5	1.3	1.6	0.4	2.2	0.4	-2.2	1.6	0.6	-0.2	-2.0	-0.5	1.2
Smoking status: Previous	1.5	2.2	7.4	1.5	0.5	1.5	1.1	0.6	2.1	1.4	1.2	2.0	-0.0	0.9	-2.2	0.0	-0.2	-0.5	-2.2	-2.1	-2.7	1.3
Average weekly red wine intake	1.5	2.2	6.1	-0.8	-1.5	-1.4	-1.5	-1.7	1.3	1.7	-1.4	-1.5	-1.3	-1.7	-1.9	-0.8	-1.8	-1.6	-2.5	0.1	-0.5	-1.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.5	1.8	4.1	1.9	1.2	1.5	1.6	1.1	1.4	1.6	1.4	0.9	1.1	1.9	-0.6	-0.1	0.7	0.1	-0.8	-1.5	-2.0	1.8
Mineral and other dietary supplements	1.5	2.1	5.3	1.6	1.7	1.9	1.7	1.8	-0.2	0.7	1.7	1.0	0.7	1.8	0.1	-1.2	1.4	0.7	-0.3	-2.3	-1.7	2.0
Age when periods started (menarche)	1.4	3.4	7.5	1.8	1.6	2.6	2.4	2.7	-0.2	-0.2	2.3	1.5	2.1	1.8	1.7	0.4	2.7	2.2	1.6	0.2	-0.5	2.3
Qualifications: None of the above	1.4	3.1	14.7	2.6	1.0	1.4	1.7	1.0	1.3	1.9	1.6	1.2	1.6	1.6	-1.8	0.4	-0.1	-1.0	-1.1	-2.3	-3.8	2.1
Diabetes (self-reported)	1.4	2.1	7.2	0.9	1.6	1.3	1.5	1.6	1.5	1.4	1.5	1.7	0.1	1.7	-1.0	-0.8	0.7	0.8	-1.8	-2.7	-1.6	1.4
Qualifications: A levels/AS levels or equivalent	1.4	3.0	13.6	-1.4	-1.0	-1.8	-2.1	-1.1	-1.0	-1.6	-1.9	-0.8	-1.3	-1.4	2.5	-0.6	-0.1	0.6	1.2	2.5	3.7	-2.4
Suffer from ‘nerves’	1.4	2.2	5.0	2.1	1.0	1.6	1.5	1.5	1.9	0.7	1.8	2.2	1.2	1.7	-0.9	0.4	1.2	1.4	-0.9	-1.6	-1.6	1.6
Medication: Aspirin	1.4	1.8	5.4	1.0	0.6	1.9	1.7	1.6	-0.3	-0.8	1.6	1.9	2.3	1.4	0.0	1.4	1.4	1.5	0.8	0.2	-0.5	1.4
Diabetes diagnosed by doctor	1.4	2.3	7.0	0.8	1.8	1.6	1.8	1.7	0.9	1.4	1.8	1.6	0.7	1.8	-1.1	-1.0	1.0	0.8	-1.6	-2.6	-1.8	1.7
Alcohol drinker status: Never	1.4	1.7	4.5	0.3	-2.1	-1.6	-1.9	-1.6	-0.6	0.0	-1.8	-1.2	-0.2	-0.8	-0.6	-1.1	-1.8	-2.0	-0.8	-0.0	-0.1	-1.8
Age started oral contraceptive pill	1.4	1.8	15.7	-0.4	0.3	0.4	-0.0	0.3	1.2	-2.8	1.0	0.1	0.5	-0.1	0.6	4.0	0.6	0.7	1.8	1.7	-0.1	0.0
Worry (Nagel 2018)	1.3	2.8	6.9	2.3	1.0	1.7	1.7	1.9	2.1	1.0	2.2	2.6	0.9	2.5	-0.0	0.6	1.5	1.4	-0.3	-1.2	-1.9	2.0
Maternal smoking around birth	1.3	1.8	4.6	1.1	1.1	1.7	2.0	1.1	-0.3	0.9	1.7	1.2	0.1	1.7	-1.0	-0.4	0.8	0.3	-0.8	-2.1	-2.1	2.1
Bilateral oophorectomy (both ovaries removed)	1.3	1.5	8.5	0.9	0.1	0.3	-0.3	0.8	0.2	-1.3	-0.2	-0.3	-2.9	-0.3	2.3	0.3	1.2	1.2	1.7	1.0	1.9	-0.4
Trunk fat mass	1.3	5.4	11.1	2.5	2.5	3.3	3.3	2.8	1.5	1.3	2.8	2.6	2.0	2.3	-0.3	0.4	2.7	2.8	-0.4	-2.1	-1.2	3.1
Medication: Lansoprazole	1.3	1.4	3.3	0.7	1.6	1.5	1.7	1.4	0.2	0.5	1.8	1.7	1.2	0.8	0.3	0.8	1.3	1.1	0.6	-0.7	-1.2	1.8
Hypothyroidism/myxoedema (self-reported)	1.3	2.6	5.4	2.1	1.3	1.6	1.5	2.1	1.6	2.3	2.0	1.7	1.1	2.1	-0.5	-0.2	1.5	1.2	-0.5	-1.8	-1.6	1.6
Neck or shoulder pain in last month	1.3	1.8	5.1	1.8	0.8	1.4	1.3	1.4	1.4	1.1	1.6	2.3	-0.5	1.2	-0.2	-1.0	1.0	1.2	-1.2	-1.9	-1.5	1.4
Had major operations	1.3	1.6	5.7	0.9	0.2	0.8	1.1	-0.3	1.6	0.5	1.1	1.2	1.3	1.2	-2.3	0.2	-0.5	-0.9	-1.0	-2.0	-2.4	1.1
Illnesses of siblings: Diabetes	1.3	1.6	8.5	0.8	0.5	1.0	0.8	0.2	2.4	0.9	0.4	1.0	0.5	-0.0	-2.9	0.6	-0.5	-0.2	-2.0	-1.8	-1.9	0.9
Osteoarthritis (self-reported)	1.3	1.7	6.8	1.6	0.1	0.3	0.3	-0.2	2.1	1.0	0.3	0.9	1.5	0.4	-2.6	0.4	-1.0	-0.9	-1.9	-1.1	-2.6	0.6
Medication: Blood pressure	1.3	2.5	7.3	1.0	1.8	1.3	1.1	2.2	0.6	-2.5	1.5	1.5	0.9	1.2	1.4	1.1	2.5	2.7	2.0	0.5	1.1	0.9
Myopia	1.3	1.9	4.2	1.6	2.1	1.8	1.8	1.1	1.3	0.2	1.7	1.9	1.3	1.8	-0.1	0.0	1.5	1.6	-0.2	-1.1	-0.6	1.6
Pain experienced in last month	1.3	2.2	5.3	-1.6	-2.3	-1.7	-2.0	-1.4	-1.1	-0.5	-1.5	-2.1	-0.5	-2.2	-0.3	1.1	-1.0	-1.0	0.7	1.9	1.2	-1.8
Depressed Affect (Nagel 2018)	1.2	2.4	9.1	1.9	1.4	1.4	1.4	0.6	3.0	-0.3	1.8	2.2	1.6	2.5	-1.3	1.1	0.8	0.9	-0.8	-1.2	-1.5	1.4
Schizophrenia (2018)	1.2	2.5	6.5	-1.8	-2.3	-2.0	-1.6	-2.1	0.0	1.0	-1.8	-1.2	-1.1	-1.8	-1.7	-0.4	-2.6	-1.6	-1.7	0.0	-0.0	-1.7
Primary Biliary Cirrhosis	1.2	1.7	4.4	0.8	0.4	1.2	1.3	0.9	1.9	1.2	1.3	1.4	0.7	1.4	-2.1	1.1	0.2	0.4	-1.3	-2.0	-1.9	1.3
Number of treatments/medications taken	1.2	2.1	6.0	2.2	1.4	1.4	1.2	2.4	1.0	-0.3	1.8	2.1	0.1	1.7	0.4	0.4	2.1	1.9	1.3	-0.5	-0.3	1.1
Qualifications: CSEs or equivalent	1.2	1.6	4.5	2.0	0.3	1.0	1.1	-0.2	2.1	1.4	0.9	1.2	1.9	2.1	-1.3	0.5	-0.2	-0.2	-1.1	-1.3	-1.4	1.0
Exposure to tobacco smoke at home	1.2	1.3	4.8	1.4	1.2	1.3	1.0	1.0	0.4	1.2	1.0	1.4	-1.0	0.8	-0.5	-1.6	0.5	-0.2	-0.5	-2.2	-1.4	1.2
Qualifications: College or University degree	1.2	3.9	19.4	-2.1	0.0	-1.2	-1.5	-0.4	-0.8	-2.1	-1.2	-1.1	-1.8	-1.1	3.3	-0.1	1.0	1.8	2.4	3.1	4.4	-1.9
Emphysema/chronic bronchitis	1.2	1.4	3.3	1.6	1.1	1.6	1.6	1.8	0.3	-0.0	1.4	0.9	0.0	1.2	1.0	-0.7	1.6	1.4	0.3	-1.1	-0.3	1.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.2	1.4	4.9	-1.2	-1.3	-1.6	-1.1	-1.9	-0.8	-0.1	-1.3	-1.0	-0.2	-1.3	-0.5	-0.1	-1.8	-2.2	-0.7	0.3	-0.7	-0.9
Mood swings	1.2	2.1	5.1	1.7	1.2	1.7	1.4	1.2	2.2	-0.2	1.9	1.9	1.4	2.2	-0.8	1.4	1.2	1.2	0.2	-0.8	-1.3	1.5
Osteoporosis (self-reported)	1.2	1.5	4.2	-0.8	-1.1	-1.0	-0.8	-1.5	-1.3	1.0	-0.8	-0.3	-1.3	-0.7	-0.7	-2.0	-1.7	-2.0	-1.5	-1.7	-0.9	-0.6
Ovarian Cancer	1.1	1.4	3.9	0.5	1.2	1.1	1.1	1.3	-1.7	-0.2	0.8	0.4	0.5	1.2	2.0	-0.0	1.7	1.6	1.8	0.4	1.3	0.9
Waist Hip Ratio (WHR)	1.1	5.0	16.3	2.6	0.5	0.8	0.8	0.2	1.9	2.4	0.6	2.4	1.4	4.0	-2.2	-3.3	-0.8	-1.4	-3.1	-4.0	-2.7	0.9
Lung FEV1/FVC ratio	1.1	5.6	12.5	-3.5	-2.2	-2.2	-2.1	-2.4	-3.2	-1.1	-2.9	-3.5	-3.5	-2.9	0.8	-1.3	-2.3	-1.9	-0.3	1.5	1.7	-2.1
Medication: Metformin	1.1	1.5	6.0	0.2	1.1	0.9	1.0	0.5	1.2	1.9	0.8	0.8	0.5	0.6	-1.5	-1.1	-0.0	0.0	-2.5	-2.2	-1.8	0.9
Average weekly fortified wine intake	1.1	1.3	3.7	-1.2	-1.4	-1.3	-1.6	-0.9	-0.4	-1.1	-1.2	-0.5	-1.1	-0.9	0.1	0.8	-0.6	-0.4	0.9	1.9	1.4	-1.6
Multivitamins +/- minerals	1.1	1.4	5.0	-1.1	-1.1	-1.2	-0.9	-1.5	-0.1	-1.4	-0.9	-1.2	-0.9	-0.4	-0.1	1.9	-0.7	-0.1	1.0	2.2	1.5	-1.2
Illnesses of siblings	1.1	1.5	5.7	-1.3	-1.4	-1.3	-1.2	-1.3	-2.4	0.8	-1.1	-1.5	-1.2	-0.6	0.9	-1.9	-0.9	-1.7	-0.2	0.4	0.3	-1.0
Trunk fat-free mass	1.1	6.4	16.3	-2.8	-2.4	-3.3	-3.2	-2.8	1.1	-1.3	-3.4	-3.7	-1.7	-4.0	-0.7	-0.9	-2.4	-1.4	-1.0	2.0	2.6	-3.3
Frequency of tiredness / lethargy in last 2 weeks	1.1	1.8	5.6	1.6	2.2	1.3	1.6	1.5	0.7	-1.5	1.2	1.1	-0.1	2.4	1.0	-0.3	1.8	1.3	1.3	-0.6	0.3	1.4
Medication: Ibuprofen (e.g. Nurofen)	1.1	1.4	5.7	0.4	0.4	0.6	0.4	1.8	-0.3	-1.6	0.8	0.9	0.3	-0.2	1.3	1.0	1.9	2.4	1.8	0.9	1.4	0.1
Depression (self-reported)	1.1	1.4	5.5	1.7	1.0	1.3	1.5	0.7	2.3	0.2	1.4	1.7	0.6	1.1	0.1	0.9	1.0	1.2	0.2	-0.3	-0.6	1.4
Trunk predicted mass	1.1	6.2	16.2	-2.7	-2.4	-3.2	-3.1	-2.7	1.1	-1.3	-3.4	-3.6	-1.7	-4.0	-0.6	-0.9	-2.3	-1.3	-0.9	2.0	2.6	-3.3
Hair/balding pattern: Pattern 4	1.1	2.6	5.9	1.4	1.8	2.3	2.0	1.7	0.0	-0.2	2.4	2.3	0.8	2.1	0.7	1.0	2.0	1.2	0.7	-1.5	-1.3	2.0
Arm fat-free mass (right)	1.1	5.7	13.0	-2.6	-2.3	-3.1	-2.9	-2.8	1.0	-0.5	-3.3	-3.6	-1.5	-3.6	-1.1	-1.1	-2.5	-1.6	-1.6	1.4	2.0	-3.1
Qualifications: NVQ or HND or HNC or equivalent	1.1	1.4	3.3	-1.5	-1.0	-1.3	-0.9	-1.8	-0.5	-1.1	-1.5	-1.3	-0.6	-1.4	-1.3	0.3	-1.6	-0.5	-0.9	1.1	1.1	-1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.1	2.4	4.8	-2.1	-2.1	-1.5	-1.8	-1.9	-0.9	-0.8	-1.8	-2.2	-1.7	-1.5	-0.7	1.2	-2.0	-1.5	-0.2	1.0	0.4	-1.8
Lupus	1.0	1.5	4.9	-0.9	-2.2	-2.0	-1.8	-1.6	-0.8	0.1	-1.3	-0.6	-0.2	-0.8	-0.8	-0.3	-1.6	-1.5	-0.5	1.1	0.1	-1.5
Supplements: Zinc	1.0	1.1	5.1	-0.1	0.7	-0.1	0.2	0.6	0.3	-2.3	0.1	0.2	-1.0	0.2	1.1	1.2	0.8	1.4	1.4	1.5	1.9	-0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	1.0	1.4	5.9	1.2	-0.1	-0.1	-0.0	-0.2	1.5	1.3	0.1	0.8	-0.5	1.4	-2.0	-1.0	-0.8	-0.8	-2.0	-2.4	-1.3	0.0
Medication: Levothyroxine sodium	1.0	1.6	5.2	1.9	1.1	1.2	0.8	2.3	1.1	0.6	1.5	1.6	0.8	0.8	0.7	1.0	2.0	2.1	0.9	-0.3	0.0	0.8
Leg fat percentage (right)	1.0	3.7	11.5	2.1	1.8	2.0	2.2	1.3	1.2	2.4	1.8	2.2	1.5	2.2	-1.6	-1.3	0.7	0.4	-1.9	-3.4	-2.3	2.2
Loneliness, isolation	1.0	1.3	5.8	0.7	0.2	-0.7	-0.6	-1.0	1.9	1.1	-0.6	0.2	-1.1	0.4	-1.5	-1.9	-0.9	-0.8	-2.4	-1.7	-0.5	-0.6
Smoking status: Current	1.0	1.6	4.8	-1.4	-0.7	-0.4	0.1	-0.8	-1.5	1.2	-0.0	-0.5	-0.6	-0.0	-1.4	-2.2	-1.3	-1.7	-1.9	-2.0	-2.0	0.3
Heart disease (siblings)	1.0	1.2	3.0	1.7	1.4	1.2	0.9	1.5	1.5	-0.4	1.1	1.6	0.6	0.7	0.9	1.1	1.3	1.4	0.9	-0.1	-0.1	0.8
Bipolar Disorder (2018)	0.9	1.4	5.4	-0.6	0.7	-0.0	0.1	0.1	-1.6	-0.9	-0.5	-0.6	-1.6	-0.4	2.3	-0.7	0.7	0.9	2.1	1.5	2.2	-0.2
Chronotype (morning person)	0.9	2.1	5.8	1.9	1.0	1.7	1.6	0.9	2.4	-0.0	1.7	1.3	1.5	1.7	-1.7	1.8	0.7	0.4	-0.3	-1.1	-1.8	1.7
Current tobacco smoking	0.9	1.4	4.5	-1.2	-0.4	-0.2	0.2	-0.5	-1.3	1.5	0.2	-0.2	-0.6	0.2	-1.1	-2.1	-1.0	-1.4	-1.7	-2.0	-2.0	0.4
Supplements: Glucosamine	0.9	1.2	4.0	-0.5	-1.1	-1.1	-0.9	-0.9	1.9	1.7	-0.6	0.2	-0.3	-0.9	-1.9	-0.4	-1.2	-0.6	-2.0	-0.8	-0.4	-0.8
Ever unenthusiastic/disinterested for a whole week	0.9	1.0	4.5	-0.7	0.2	-0.1	-0.1	0.2	-2.1	-1.1	-0.3	-0.3	-1.6	0.7	1.9	-1.2	0.7	0.9	1.2	0.6	1.5	-0.3
Neuroticism score	0.9	1.9	6.8	2.3	0.9	1.3	1.1	1.2	2.3	0.3	1.5	2.2	0.3	2.6	-0.5	0.2	1.0	1.0	-0.5	-1.2	-1.2	1.2
Arm fat percentage (right)	0.9	3.6	8.1	1.4	2.0	2.7	2.9	2.2	0.1	1.1	2.6	2.1	1.2	2.1	-0.7	0.6	1.7	1.6	-0.1	-2.3	-1.9	2.8
Falls in the last year	0.9	1.2	2.6	1.0	1.0	1.1	1.3	1.2	-0.7	-0.4	1.1	1.5	1.0	1.6	0.9	-1.5	1.3	1.1	0.1	-1.3	-0.1	1.1
Qualifications: O levels/GCSEs or equivalent	0.9	1.4	3.5	-1.1	-0.9	-1.5	-1.7	-0.5	-1.0	-0.9	-1.2	-0.6	-1.5	-1.2	1.2	-1.7	-0.2	-0.1	0.2	0.2	1.9	-1.8
Blood clot in the leg (DVT)	0.9	1.2	5.4	1.9	1.6	1.4	1.1	1.1	2.3	-0.5	1.0	1.0	0.3	0.8	0.8	0.2	1.0	1.1	0.1	-0.8	-0.4	1.0
Chronic bronchitis/emphysema (mother)	0.9	1.1	4.6	0.7	-0.4	0.1	-0.0	0.2	-0.1	1.6	0.0	0.6	-0.9	-0.7	-1.3	-1.5	-0.6	-0.7	-1.7	-2.1	-1.6	0.2
Wheeze or whistling in the chest in last year	0.9	1.6	5.4	1.2	2.1	0.9	1.6	0.7	0.2	0.1	1.4	2.3	-0.5	1.2	0.1	-1.8	1.2	0.7	-0.0	-1.6	-0.6	1.7
Mean time to correctly identify matches	0.9	1.8	7.1	-0.7	0.7	0.3	0.6	0.7	-0.6	-1.6	0.4	0.3	-0.9	-1.0	2.3	1.8	1.2	1.1	2.7	2.6	1.2	0.7
Arm predicted mass (right)	0.9	4.7	11.1	-2.4	-2.0	-2.8	-2.7	-2.6	1.2	-0.3	-3.0	-3.3	-1.2	-3.3	-1.1	-1.0	-2.3	-1.5	-1.6	1.2	1.8	-2.8
Whole body fat-free mass	0.9	5.1	13.9	-2.9	-2.1	-2.8	-2.6	-2.4	0.6	-1.5	-2.9	-3.5	-1.5	-3.7	-0.5	-0.3	-1.9	-0.9	-0.6	2.1	2.5	-2.8
Leg fat-free mass (right)	0.9	4.6	12.5	-3.2	-2.0	-2.4	-2.2	-1.9	-0.3	-1.8	-2.6	-3.5	-1.6	-3.5	-0.1	0.4	-1.4	-0.3	0.2	2.5	2.7	-2.5
Leg predicted mass (right)	0.9	4.8	12.7	-3.3	-2.0	-2.5	-2.3	-2.0	-0.4	-1.9	-2.6	-3.6	-1.6	-3.5	-0.2	0.3	-1.5	-0.3	0.2	2.4	2.8	-2.5
Ever taken oral contraceptive pill	0.9	1.0	5.0	-0.6	0.2	0.3	0.2	0.3	-1.7	-1.3	0.1	-0.1	-0.8	-0.4	1.7	0.7	0.7	0.4	2.2	1.4	0.8	0.2
Deep venous thrombosis (DVT) (self-reported)	0.9	1.1	6.6	2.0	1.5	1.2	0.9	0.8	2.6	-0.4	0.8	0.9	0.2	1.0	0.5	0.2	0.6	0.7	-0.2	-0.8	-0.7	0.9
Intelligence (Savage-Jansen 2018)	0.8	2.4	11.4	-1.4	0.1	-0.6	-0.6	0.2	-0.5	-1.0	-1.1	-1.9	-0.9	-1.4	2.3	1.2	0.6	1.1	2.5	3.4	2.9	-0.9
Blood Eosinophil Count	0.8	5.8	21.3	1.4	-0.7	0.3	0.7	-1.2	3.6	3.9	0.4	1.2	1.5	1.1	-4.6	-1.1	-1.7	-1.8	-4.2	-3.7	-3.5	0.7
Severe depression (siblings)	0.8	0.8	2.6	1.1	1.0	0.9	1.1	1.3	0.1	0.1	1.2	1.6	0.1	0.6	0.5	0.3	1.3	1.1	0.7	-0.3	-0.4	1.3
Fed-up feelings	0.8	1.4	6.5	1.6	0.2	0.3	0.3	0.4	2.6	0.4	0.8	1.4	0.0	2.5	-1.2	-0.2	0.2	0.3	-1.2	-1.9	-0.8	0.3
Relative age voice broke	0.8	1.3	4.6	-0.4	1.5	0.9	1.1	1.1	-0.5	-0.5	0.8	0.2	0.1	0.5	1.9	0.2	1.7	1.3	2.1	1.1	1.4	0.9
Stomach or abdominal pain in last month	0.8	0.9	3.4	0.6	1.4	0.9	0.9	1.4	-0.1	1.1	0.6	0.7	1.3	0.8	-0.3	-1.9	0.6	0.7	-0.5	-1.3	-0.8	0.9
Hearing difficulty/problems with background noise	0.8	1.3	5.8	-0.9	-0.2	-0.6	-0.7	-0.1	0.1	-2.4	-0.1	-0.3	-1.5	-0.6	0.8	1.6	0.4	0.8	1.8	1.6	1.6	-0.9
Mouth/teeth dental problems	0.8	1.2	4.6	-0.5	-1.5	-0.9	-1.2	-1.4	1.4	-0.5	-1.0	-1.1	-0.4	-0.8	-2.1	0.9	-1.5	-0.8	-1.0	0.0	0.1	-1.4
Birth weight of first child	0.8	1.5	5.0	1.7	1.1	1.5	1.3	1.3	2.2	0.8	1.1	1.3	1.2	0.9	0.6	-1.2	1.3	1.3	-0.8	-1.0	-0.5	1.2
High blood pressure (siblings)	0.8	1.1	4.6	1.0	0.8	0.5	0.7	0.9	2.0	-1.1	0.7	0.5	1.1	0.7	-0.9	2.1	0.8	1.8	0.6	0.3	0.8	0.4
Age at first live birth	0.8	1.3	5.0	-1.5	-1.3	-0.7	-1.0	-0.9	0.7	-1.6	-0.9	-0.9	0.3	-1.1	0.5	1.0	-0.2	0.7	0.1	2.2	2.1	-1.5
Whole body fat mass	0.8	3.2	6.6	1.9	1.9	2.5	2.6	2.0	1.4	1.4	2.0	1.8	1.5	1.7	-0.9	0.0	1.7	1.9	-0.9	-2.1	-1.2	2.4
Friendships satisfaction	0.8	1.0	3.7	-0.4	1.1	0.1	0.5	0.2	-0.9	-1.8	0.2	0.0	-0.2	0.4	1.0	0.8	1.1	1.4	1.5	1.9	1.7	0.4
Qualifications: nursing, teaching	0.8	1.2	5.5	-0.2	0.1	0.0	-0.5	1.0	-0.4	-1.8	0.2	0.1	0.2	-0.6	1.0	0.9	1.6	1.9	1.6	1.5	2.3	-0.7
Whole body water mass	0.8	4.8	13.4	-2.8	-2.0	-2.7	-2.6	-2.3	0.7	-1.5	-2.8	-3.4	-1.5	-3.7	-0.4	-0.2	-1.8	-0.8	-0.5	2.1	2.5	-2.8
Medication: Paracetamol	0.8	1.3	3.3	0.9	0.5	1.0	1.3	1.4	-0.7	-1.7	1.1	1.4	-0.2	0.9	1.3	0.6	1.4	1.3	1.8	0.4	0.5	1.2
Risk taking	0.8	1.2	3.5	-1.9	-0.2	-1.2	-1.0	-1.7	-0.2	-0.7	-1.2	-1.6	-1.5	-0.9	0.2	-0.8	-1.3	-1.2	0.1	0.8	0.8	-1.0
Heart attack/myocardial infarction (self-reported)	0.8	1.0	4.1	-0.7	-2.0	-1.0	-1.5	-1.0	-0.9	-0.6	-1.1	-1.2	0.2	-0.7	-0.3	-0.6	-1.3	-1.4	-0.4	-0.3	-0.2	-1.4
Bipolar Disorder or Schizophrenia	0.7	1.7	4.4	-1.8	-1.3	-1.6	-1.2	-1.6	-0.9	0.2	-1.7	-1.3	-2.1	-1.6	0.1	-0.7	-1.5	-0.7	-0.0	1.0	1.3	-1.4
Crohns Disease (2017)	0.7	1.4	3.8	1.4	1.6	1.1	1.1	0.6	1.9	0.1	1.2	1.7	1.8	1.2	-1.1	0.8	0.2	-0.2	-0.1	-0.1	-1.9	1.4
HDL Cholesterol	0.7	1.1	5.2	0.4	-0.1	0.4	0.2	0.4	1.2	1.5	0.5	0.7	-0.8	-0.3	-1.2	-1.9	-0.0	-0.5	-1.8	-2.3	-1.2	0.4
Blood White Count	0.7	5.5	18.7	1.1	0.2	1.7	2.1	0.3	-0.9	3.6	2.0	1.6	2.1	1.7	-4.3	0.6	-0.1	-0.7	-3.5	-3.7	-4.1	2.4
Vitamin and mineral supplements	0.7	1.0	4.4	0.9	0.8	0.6	0.4	0.8	0.8	1.6	0.2	0.5	0.1	0.3	-0.9	-1.8	0.1	-0.3	-1.5	-2.1	-1.4	0.6
Had menopause	0.7	0.8	3.5	1.6	0.2	0.7	0.3	0.8	1.3	-0.3	1.0	1.4	0.3	0.5	-0.5	0.2	0.1	-0.4	-0.3	-1.5	-1.9	0.6
Worrier / anxious feelings	0.7	1.3	5.8	2.1	-0.1	0.8	0.6	1.5	1.0	-0.2	1.4	1.9	-0.2	2.4	0.9	-0.2	1.2	0.9	0.6	-0.6	-0.9	0.8
Forced expiratory volume in 1-second (FEV1)	0.7	2.5	5.2	-1.8	-1.8	-1.1	-1.2	-2.3	0.5	0.7	-1.9	-2.3	-1.2	-2.1	-1.8	1.4	-2.3	-1.4	-1.4	1.2	0.3	-1.3
Standing height	0.7	7.1	23.4	3.8	2.6	3.0	2.5	2.9	4.5	-0.9	1.9	2.6	1.4	1.0	2.0	0.3	4.2	4.8	0.7	0.8	2.3	1.8
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.1	3.2	0.7	-0.8	-0.7	-0.8	-1.1	1.7	0.4	-0.2	0.7	-0.6	-0.4	-1.8	-0.0	-1.3	-1.3	-1.5	-1.5	-1.5	-0.6
Pulse wave reflection index	0.7	0.9	2.2	-1.5	-0.4	-1.1	-1.1	-1.0	-1.3	-1.4	-1.0	-1.0	0.4	-0.5	0.5	-0.2	-0.9	-1.2	0.7	1.1	0.3	-0.9
Glaucoma (self-reported)	0.7	0.8	3.7	1.3	0.5	0.2	0.4	0.5	1.9	0.9	0.7	1.5	0.4	0.7	-0.3	-1.1	0.4	0.7	-1.1	-1.0	-0.6	0.3
Number of full brothers	0.7	0.9	2.8	0.4	1.3	1.7	1.6	0.7	0.3	0.8	1.3	1.0	0.6	0.7	0.7	-0.5	1.1	0.5	0.3	-0.1	-0.9	1.6
Medication: Omeprazole	0.7	0.8	2.6	0.3	-1.4	-1.0	-1.4	-0.6	-0.2	0.3	-1.0	-0.5	-0.4	-0.3	-1.2	-0.6	-1.2	-1.6	-0.8	-0.9	-0.9	-1.1
Illness, injury, bereavement, stress in last 2 years	0.7	0.8	2.2	1.0	0.3	0.9	0.6	0.6	1.5	-0.8	0.5	0.2	0.7	-0.1	0.8	1.4	1.1	1.2	1.0	1.4	0.7	0.4
Medication: Gliclazide	0.7	0.8	4.9	0.3	0.7	0.5	0.9	0.3	0.7	0.5	0.4	0.2	0.1	0.7	-0.4	-2.2	0.1	-0.1	-1.5	-1.7	-0.8	0.8
Leg fat percentage (left)	0.7	2.6	11.0	1.2	1.0	1.1	1.4	0.4	1.0	2.6	0.9	1.2	0.9	1.3	-2.2	-1.4	-0.3	-0.5	-2.4	-3.3	-2.3	1.4
Pack years of smoking	0.7	1.0	3.5	0.0	-0.2	-1.3	-1.3	-1.3	-0.5	0.2	-1.3	-1.0	-1.4	-0.2	-0.0	-1.9	-1.0	-1.2	-0.3	-0.3	0.7	-1.3
Depression (Nagel 2018)	0.6	1.0	2.7	1.6	0.4	0.4	0.4	0.2	1.6	0.9	0.6	0.9	-0.0	1.5	-1.6	0.7	-0.2	-0.1	-1.1	-1.6	-1.2	0.5
Crohns Disease (2012)	0.6	1.0	3.6	1.4	0.6	1.4	1.2	0.4	1.3	-0.1	0.9	1.2	0.5	0.8	-1.1	0.3	0.1	-0.3	-0.6	-0.6	-1.9	1.4
LDL Cholesterol	0.6	0.9	2.6	1.0	1.1	1.0	0.7	0.9	0.6	1.1	1.0	1.6	1.2	1.2	-0.9	0.1	0.2	0.2	-0.8	-1.4	-1.3	0.6
Height	0.6	10.7	38.4	4.6	3.1	2.6	2.2	3.4	6.2	-1.3	1.6	3.1	0.1	0.2	3.8	0.1	4.8	6.2	1.4	1.4	4.2	1.2
Sensitivity / hurt feelings	0.6	1.0	3.2	1.4	1.1	1.2	1.2	0.9	0.8	0.9	1.1	1.6	0.7	1.8	-0.1	-0.1	0.9	0.8	-0.1	-0.5	-0.7	1.3
Relative age of first facial hair	0.6	1.3	3.4	-0.4	1.7	1.4	1.6	1.7	-0.2	-0.9	1.3	0.5	0.5	-0.0	1.2	0.7	1.5	1.0	1.9	0.4	-0.1	1.7
Taking other prescription medications	0.6	1.0	3.5	1.6	0.1	-0.4	0.0	-0.3	1.5	0.0	0.1	1.1	-0.8	0.8	-1.9	-0.7	-0.6	-0.9	-1.2	-1.6	-1.3	0.1
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	3.2	0.6	0.6	0.1	0.4	0.6	0.5	0.1	0.0	0.3	-0.1	-0.6	0.7	1.6	0.7	1.1	1.8	1.4	1.4	0.3
Frequency of tenseness / restlessness in last 2 weeks	0.6	0.9	3.6	1.5	0.3	0.4	0.2	0.9	0.2	1.7	0.3	0.5	-1.1	1.5	0.3	-1.6	0.5	0.5	-0.7	-1.9	-0.2	0.2
Heart attack	0.6	0.8	4.0	-0.3	-2.0	-0.9	-1.4	-0.8	-0.6	-0.5	-0.8	-0.7	0.3	-0.5	-0.3	-0.4	-1.0	-1.2	-0.3	-0.3	-0.3	-1.3
Age at last live birth	0.6	0.9	3.4	-1.6	-1.2	-1.0	-0.9	-1.2	-0.2	-0.8	-0.8	-0.9	-0.1	-0.8	0.1	0.4	-0.7	-0.1	0.2	1.9	1.3	-1.2
Arm fat percentage (left)	0.6	2.2	5.4	0.9	1.5	2.1	2.3	1.8	-0.1	1.1	2.0	1.6	0.7	1.7	-0.7	0.3	1.4	1.4	-0.2	-2.0	-1.3	2.2
Commuting to job workplace: Walk	0.6	0.6	2.3	0.8	0.5	0.6	0.4	0.8	-0.2	0.6	0.6	1.5	-0.5	0.6	1.2	0.2	1.1	1.5	0.6	0.7	0.6	0.3
Eye problems/disorders: Cataract	0.6	0.7	5.8	-0.2	0.0	-0.6	-0.6	-0.1	-1.0	1.1	-0.8	-0.6	-1.4	-0.8	0.2	-2.4	-0.5	-0.5	-0.5	-0.4	0.2	-0.6
Eye problems/disorders: Glaucoma	0.6	0.7	3.8	1.0	0.2	-0.1	0.0	0.2	1.9	0.8	0.6	1.3	0.4	1.1	0.0	-1.3	0.1	0.2	-0.9	-0.7	-0.6	-0.0
Ever smoked	0.6	1.0	4.7	-0.5	0.4	0.8	0.8	-0.1	0.6	0.7	0.9	1.0	0.1	0.3	-1.5	-0.6	-0.5	-0.8	-1.9	-1.5	-2.2	0.9
Arm fat-free mass (left)	0.6	3.1	9.8	-2.2	-1.3	-2.2	-2.0	-2.0	0.9	-0.6	-2.3	-2.9	-0.7	-3.1	-0.8	-0.7	-1.7	-0.9	-1.2	1.0	1.6	-2.2
Fractured/broken bones in last 5 years	0.6	0.8	3.0	0.1	0.6	1.1	1.0	0.8	-0.8	-0.2	1.4	0.8	0.1	0.9	0.5	-1.3	0.9	0.3	-0.2	-1.7	-1.0	1.1
Alcohol drinker status: Previous	0.6	0.7	4.8	0.9	0.0	-0.3	-0.6	0.6	1.3	-0.1	-0.5	-0.2	-0.4	-0.4	0.6	2.2	0.2	0.9	1.0	1.3	0.8	-0.7
Arm predicted mass (left)	0.6	3.2	9.0	-2.1	-1.4	-2.2	-2.1	-2.1	1.0	-0.6	-2.3	-2.9	-0.9	-3.0	-0.7	-0.7	-1.8	-1.1	-1.2	1.0	1.6	-2.2
Alzheimer’s Disease (in mother)	0.5	0.5	2.4	-0.4	-0.4	-0.6	-0.6	0.5	-1.0	-1.0	-0.3	-0.8	-1.5	-1.6	0.8	-0.5	0.1	-0.1	0.7	0.0	0.2	-0.3
Alzheimer’s Disease (including proxy)	0.5	0.7	2.7	-0.1	0.0	-0.3	-0.3	0.6	-1.6	-1.1	-0.6	-0.9	-1.3	-1.1	1.1	-0.8	0.2	0.2	1.0	0.3	0.9	-0.2
Major Depression (MDD)	0.5	0.6	4.2	-0.6	-0.7	-0.8	-0.6	-0.7	-1.2	-0.4	-0.9	-0.9	-2.0	-0.3	0.3	-0.7	-0.8	-0.7	0.4	0.4	0.4	-0.5
Reaction Time	0.5	0.9	3.8	0.1	0.9	0.9	1.1	0.8	0.2	-0.1	0.9	0.9	0.3	-0.2	0.7	2.0	0.9	0.8	1.5	1.3	-0.1	1.2
Age at First Birth	0.5	0.8	2.6	-0.5	-1.0	-1.0	-1.1	-1.6	0.2	-0.2	-0.9	-1.1	0.1	-0.8	-0.3	0.7	-1.2	-1.3	-0.3	1.2	-0.0	-1.0
Body Mass Index (BMI) (2010)	0.5	0.7	2.0	-1.1	0.0	-0.6	-0.6	0.0	-0.3	-0.1	-0.5	-1.1	-1.3	-0.8	1.1	0.4	0.2	0.7	1.0	1.0	1.4	-0.7
Ulcerative Colitis	0.5	0.7	3.1	1.0	-0.1	0.6	0.5	-0.2	1.8	0.6	0.6	0.7	-0.2	1.0	-1.7	1.4	-0.3	-0.3	-0.6	-0.2	-1.1	0.5
Allergy or Eczema	0.5	1.2	4.0	-1.6	0.8	-2.0	-1.4	-0.4	0.1	-1.5	-1.0	-0.9	-1.1	-1.2	0.8	-0.7	-0.6	-0.2	0.8	0.9	1.2	-1.4
Hypothyroidism (self reported)	0.5	1.2	3.7	1.2	0.8	1.1	1.2	1.5	0.5	1.6	1.3	0.9	0.2	1.9	0.0	-0.9	1.2	0.9	-0.2	-1.6	-0.8	1.1
Ever had hysterectomy (womb removed)	0.5	0.5	1.9	1.4	0.3	0.9	0.2	1.1	1.0	-1.1	0.5	0.2	0.4	-0.1	0.3	1.0	1.0	1.1	0.6	-0.1	0.2	0.1
Pack years adult smoking proportion	0.5	0.8	3.4	0.5	0.0	-1.0	-0.9	-1.3	-0.3	0.9	-1.0	-0.6	-1.0	0.3	-0.5	-1.8	-1.0	-1.2	-0.7	-0.6	0.2	-0.9
Tinnitus: Yes, but not now, but have in the past	0.5	0.5	2.0	0.3	-0.5	-0.7	-0.7	-0.7	1.4	0.4	-0.5	0.2	-1.2	0.7	-0.2	0.5	-0.9	-0.6	-0.8	-0.3	-0.1	-0.8
Nervous feelings	0.5	0.9	2.8	1.6	0.6	0.9	0.6	1.2	1.4	0.4	1.0	1.7	0.0	1.0	1.0	0.6	1.1	1.0	0.6	-0.2	-0.3	0.8
Fluid intelligence score	0.5	1.0	5.5	-0.9	-0.2	-0.6	-0.6	0.2	-0.3	-0.5	-0.4	-0.8	-1.4	-0.2	2.4	0.1	0.5	0.3	1.9	1.7	1.6	-0.7
Tense / ‘highly strung’	0.5	0.8	3.0	1.3	0.2	0.3	0.2	0.5	1.6	1.7	0.9	1.3	-0.9	0.6	0.0	-0.4	0.6	0.7	-0.8	-1.0	-0.6	0.3
Gout (self-reported)	0.5	0.7	5.3	0.0	-0.2	-0.4	-0.5	0.3	1.3	-0.8	0.5	1.2	-0.2	0.5	-0.8	2.3	0.1	1.1	0.6	0.7	0.2	-0.5
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.6	1.6	1.2	0.9	1.1	1.0	0.9	-0.6	0.0	0.6	0.6	-0.6	0.5	0.6	-1.0	0.6	0.1	0.1	-1.3	-0.7	1.0
Pulse wave peak to peak time	0.5	0.6	2.0	0.1	0.6	1.0	0.9	1.3	0.2	1.0	0.8	0.6	-0.4	-0.1	-0.0	0.3	1.0	1.4	-0.1	-0.8	-0.1	0.8
Medication: Ibuprofen	0.5	0.6	2.4	-0.0	-0.2	0.2	-0.1	1.0	-0.2	-1.1	0.3	0.5	-0.2	-1.0	0.7	0.6	1.1	1.5	1.1	0.6	1.2	-0.3
Medication: Allopurinol	0.5	0.6	4.7	0.4	-0.2	-0.5	-0.8	0.3	1.4	-0.6	0.3	0.8	0.3	0.5	-0.7	2.2	-0.0	0.4	1.0	0.8	-0.0	-0.7
Leg fat mass (right)	0.5	1.9	5.8	1.3	1.2	1.4	1.5	1.0	1.4	1.9	1.2	1.3	1.1	1.1	-1.6	-0.9	0.6	0.6	-1.7	-2.4	-1.5	1.5
Comparative height size at age 10	0.5	2.8	20.4	2.3	-1.2	-0.8	-1.3	-0.9	4.5	1.3	-1.3	0.8	-0.9	-1.7	-1.2	-1.6	-0.6	0.2	-2.8	-0.7	0.7	-1.5
Number of full sisters	0.5	0.6	1.3	0.1	-1.1	-0.2	-0.4	-1.1	-0.5	-1.0	-0.2	-1.0	0.8	-0.9	-1.1	1.1	-0.5	-0.8	0.4	1.1	-0.5	-0.2
Supplements: Vitamin C	0.5	0.5	2.0	-1.0	-0.3	-1.2	-0.8	-1.0	-0.4	-0.0	-0.6	-0.3	-1.4	-0.5	0.3	-0.7	-0.9	-0.8	-0.4	-0.1	0.4	-0.9
Mouth/teeth dental problems: Mouth ulcers	0.5	0.8	3.1	-0.4	1.0	0.9	1.0	1.1	-0.4	0.0	1.0	0.8	-0.1	-0.5	1.6	0.6	1.2	0.9	1.7	0.3	0.2	1.1
Breast cancer (self-reported)	0.5	0.6	2.1	-0.7	-0.6	-0.7	-0.9	-0.9	-0.1	-1.5	-0.9	-0.8	-0.7	-0.3	-1.0	-0.1	-1.2	-1.2	-0.2	0.2	-0.4	-0.8
Medication: Aspirin	0.5	0.7	3.1	0.5	-0.2	1.2	0.9	0.7	-0.5	-0.4	0.9	1.2	1.8	0.5	-0.6	1.1	0.4	0.6	0.1	0.2	-0.8	0.8
Medication: Bendroflumethiazide	0.5	0.7	1.9	0.1	0.8	0.4	0.2	1.2	0.4	-1.4	0.6	0.2	0.2	0.7	0.7	0.8	1.2	1.4	1.4	0.8	0.8	0.1
Basal metabolic rate	0.5	2.9	8.5	-2.2	-1.5	-2.0	-1.9	-1.7	0.8	-1.0	-2.2	-2.8	-1.1	-2.9	-0.6	-0.3	-1.4	-0.4	-0.7	1.4	2.0	-2.1
Irritability	0.5	0.9	4.1	0.3	-0.8	-0.5	-0.9	-0.9	2.0	1.0	-0.4	-0.1	-0.5	0.6	-1.4	-0.0	-1.2	-1.2	-1.3	-0.5	-0.9	-0.7
Commuting to job workplace: Cycle	0.5	0.6	3.5	0.0	-0.3	0.2	0.1	0.5	-1.0	-1.1	-0.1	0.1	0.1	-0.2	0.6	0.9	0.6	0.9	1.2	1.9	0.9	0.1
Medication: Omeprazole (e.g. Zanprol)	0.5	0.7	2.0	0.0	-1.3	-1.1	-1.4	-0.3	-0.9	0.2	-0.8	-0.3	-0.6	-0.5	-0.6	-0.8	-0.8	-1.3	-0.4	-0.8	-0.6	-1.1
Verbal and Numeric Reasoning (VNR)	0.4	1.0	3.6	-0.4	1.0	0.4	0.2	1.0	0.6	-0.6	-0.1	-0.4	-0.2	-0.4	1.9	1.1	0.9	1.1	1.9	1.7	1.4	0.0
Coronary Artery Disease (CAD)	0.4	0.5	2.0	1.4	0.6	0.7	0.6	0.4	1.3	0.6	0.6	0.6	1.1	-0.1	-0.8	0.0	0.4	0.3	-0.6	-0.7	-0.4	0.5
Neuroticism (2016)	0.4	0.5	1.9	0.9	0.0	0.7	0.6	0.2	0.3	-0.7	0.7	0.7	0.5	1.4	-0.6	-0.5	0.4	0.4	-0.8	-1.4	-0.7	0.5
Frequency of depressed mood in last 2 weeks	0.4	0.6	3.0	1.7	-0.1	0.0	-0.0	0.1	1.4	0.9	0.0	0.4	-0.3	1.6	-0.7	-0.0	-0.2	-0.1	-0.8	-1.0	-0.5	-0.1
Leg fat-free mass (left)	0.4	2.2	7.0	-2.3	-1.0	-1.4	-1.3	-1.0	0.2	-1.6	-1.6	-2.4	-1.0	-2.6	0.1	0.5	-0.6	0.5	0.4	2.0	2.3	-1.5
Body mass index (BMI)	0.4	1.9	4.2	-2.0	-1.2	-1.4	-1.1	-1.4	-1.0	0.8	-1.2	-1.8	-0.6	-1.5	-1.9	-0.7	-2.0	-1.7	-1.4	-1.0	-0.6	-1.0
Leg predicted mass (left)	0.4	2.1	6.4	-2.2	-1.0	-1.3	-1.2	-0.9	0.3	-1.6	-1.5	-2.3	-0.8	-2.5	0.1	0.6	-0.5	0.6	0.4	2.0	2.2	-1.5
Waist circumference	0.4	1.5	6.9	0.3	-0.2	-0.0	0.2	-0.1	0.7	1.9	-0.1	0.2	0.7	0.5	-2.0	-2.1	-0.8	-0.7	-2.4	-2.6	-1.3	0.1
Hair/balding pattern: Pattern 2	0.4	0.4	2.4	-0.7	-0.1	-0.4	-0.2	-0.3	-0.7	1.6	-0.9	-0.8	-0.3	0.3	1.0	-0.6	-0.4	-0.4	-0.0	1.1	0.5	-0.0
Had other major operations	0.4	0.5	1.5	-1.0	-0.4	-1.2	-0.8	-0.9	0.2	-0.1	-0.9	-0.5	-1.1	0.1	-0.5	0.1	-1.1	-0.7	-0.0	0.4	0.4	-0.8
Financial difficulties in last 2 years	0.4	0.5	1.6	-0.1	0.7	0.6	0.8	0.8	0.5	1.2	0.5	1.1	0.7	0.8	-0.7	0.2	0.2	0.6	-0.4	-1.1	-0.7	0.8
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	2.3	-0.1	0.4	-1.1	-0.6	-0.6	0.6	-1.2	-0.6	-0.1	-1.5	-0.1	0.2	-0.9	-0.4	-0.2	-0.0	0.1	0.8	-0.7
Medication: Ramipril	0.4	0.5	1.4	0.9	0.4	0.4	0.1	0.4	0.5	0.2	0.4	1.2	0.3	0.3	1.1	-0.5	1.1	1.1	0.6	0.5	0.9	0.1
Pulse rate	0.4	0.7	3.2	0.0	-1.2	-0.9	-1.0	-0.8	-0.7	-0.0	-1.1	-0.7	-0.9	0.3	0.5	-1.8	-0.6	-1.0	-0.4	0.0	0.7	-1.0
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.5	2.3	0.2	0.4	0.5	0.8	-0.2	-0.9	-0.0	0.3	0.5	-0.4	0.6	-1.1	-0.5	-0.3	-0.3	-1.0	-1.5	-0.8	0.8
Asthma	0.4	0.7	3.3	-0.0	0.0	-1.3	-0.7	-1.4	1.3	0.1	-0.5	0.3	0.0	-0.9	-1.8	-0.1	-1.1	-0.9	-1.0	0.0	-0.5	-0.4
Ever highly irritable/argumentative for 2 days	0.4	0.5	2.1	0.3	1.1	0.1	0.4	-0.1	-0.1	0.0	-0.3	-0.1	-1.3	-0.3	-0.6	-1.5	-0.3	-0.0	-1.3	-1.0	-0.2	0.4
Exposure to tobacco smoke outside home	0.4	0.5	2.8	0.7	0.0	0.5	0.6	0.9	-0.3	-0.1	0.8	0.5	-0.2	1.0	-0.8	0.1	0.2	0.2	-0.2	-1.7	-1.1	0.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	3.2	0.3	0.5	-0.2	0.2	-0.1	-1.2	-1.3	-0.1	0.4	-1.8	-0.2	1.0	-0.8	0.2	0.0	0.9	0.3	0.6	0.2
Medication: Seretide 50 evohaler	0.4	0.5	1.6	0.5	-0.9	-0.4	-0.1	-0.5	1.1	0.0	0.3	0.3	-0.5	0.6	-1.2	-0.3	-0.5	-0.4	-1.3	-0.9	-1.1	-0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	2.4	-0.2	0.6	0.2	0.3	-0.3	0.3	1.5	0.3	0.1	0.4	0.2	-1.2	0.5	-0.7	-0.6	-0.7	-0.3	-1.4	0.5
Pulse rate, automated reading	0.4	1.1	4.8	0.8	0.8	0.8	0.8	1.1	-1.8	-0.7	0.4	-0.5	0.1	1.4	2.2	-0.7	1.3	0.6	1.7	0.7	0.7	0.8
Family relationship satisfaction	0.4	0.5	2.3	-0.3	-0.3	-0.4	-0.4	-1.0	-1.1	0.8	-0.8	-0.9	-0.4	-0.7	-0.2	-1.5	-0.5	-0.4	-1.0	-0.5	0.2	-0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.7	3.9	2.0	0.6	0.8	0.6	0.4	1.6	0.7	0.2	0.8	0.3	1.0	0.4	-0.9	0.6	0.8	-0.9	-0.8	0.3	0.4
Handedness (chirality/laterality): Left-handed	0.4	0.5	3.0	-1.7	-0.1	-0.5	-0.3	-1.0	-0.7	-0.1	-0.6	-1.1	0.0	-0.6	-0.2	-0.7	-0.7	-0.7	-0.2	-0.1	0.3	-0.4
Long-standing illness, disability or infirmity	0.4	0.6	1.9	1.1	0.8	0.3	0.6	0.9	1.1	0.6	0.7	1.2	0.0	0.3	-1.1	-0.5	0.2	0.2	-0.8	-1.4	-1.1	0.6
Back pain experienced in last month	0.4	0.5	1.8	-0.1	0.0	-0.3	-0.4	-0.9	0.4	-0.0	-0.4	-0.1	0.3	0.5	-1.2	-0.6	-1.2	-1.3	-1.1	-0.9	-1.1	-0.3
Illnesses of father: None of the above (group 1)	0.4	0.5	2.9	-0.2	-0.8	-0.3	-0.5	-1.0	-0.5	-0.3	-0.4	-0.7	-0.3	-0.9	-0.4	-0.5	-1.0	-1.7	-0.4	-0.0	-1.1	-0.1
Miserableness	0.4	0.8	2.9	1.7	0.1	0.6	0.1	0.6	1.6	-1.0	0.6	1.6	0.3	1.3	-0.6	0.6	0.5	0.7	-0.4	-1.0	-0.1	-0.1
Ever depressed for a whole week	0.4	0.5	2.3	-0.5	0.2	0.0	-0.1	0.6	-0.7	-1.5	-0.4	-0.4	-1.2	-0.4	1.0	-1.0	0.5	1.1	-0.2	-0.7	0.9	-0.3
Leg fat mass (left)	0.4	1.7	6.0	0.8	0.8	1.0	1.2	0.5	1.4	2.1	0.8	0.7	0.8	0.6	-2.0	-0.9	0.0	0.2	-2.1	-2.4	-1.6	1.2
Mean Putamen Volume	0.3	0.3	1.9	0.3	0.2	0.2	0.3	0.6	-0.2	-0.9	0.3	0.4	1.4	0.4	0.7	-0.0	0.8	0.5	0.4	0.4	0.4	0.2
Triglycerides	0.3	0.5	2.0	0.0	1.0	0.5	0.8	0.2	-0.5	0.3	0.6	0.7	1.4	0.3	0.2	1.3	0.4	0.4	0.6	1.0	-0.2	0.8
Respiratory disease	0.3	0.7	2.2	1.5	0.8	0.3	0.7	-0.0	1.4	-0.5	0.7	1.1	1.3	0.6	-1.5	0.2	0.2	0.1	-0.3	-0.3	-0.9	0.8
Ever used hormone-replacement therapy (HRT)	0.3	0.4	1.0	-0.4	0.4	0.4	0.6	0.8	0.9	-0.0	1.0	1.0	-0.8	0.4	0.4	-0.1	0.6	0.4	0.1	-0.7	-0.7	0.6
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	3.0	0.0	0.5	0.2	0.1	0.9	1.7	0.4	0.4	0.2	-0.2	-0.5	-0.1	0.8	0.1	0.3	-0.3	-0.8	-0.6	0.1
Diabetes (father)	0.3	0.4	2.3	-0.3	-0.2	0.2	0.7	0.5	0.2	1.5	0.1	0.6	-1.3	-0.0	0.1	-0.5	0.3	0.8	-0.6	-0.5	0.5	0.5
Serious illness, injury or assault to yourself	0.3	0.4	1.4	0.9	0.1	-0.3	-0.5	0.1	0.4	-0.3	-0.4	0.0	-1.0	-0.1	1.2	-0.9	0.3	0.5	0.1	0.3	1.1	-0.7
Hayfever, allergic rhinitis or eczema	0.3	0.7	2.3	-1.2	1.4	-1.5	-0.7	-0.2	0.7	-0.4	-0.7	-0.4	-1.2	-0.6	0.5	-1.4	-0.4	-0.0	0.1	0.1	0.9	-0.8
Forced vital capacity (FVC)	0.3	1.0	3.3	-1.0	-1.0	-0.2	-0.4	-1.4	1.1	0.5	-0.8	-1.3	-0.3	-1.2	-1.7	1.8	-1.2	-0.6	-0.9	0.8	-0.0	-0.4
Pain all over the body in last month	0.3	0.4	1.1	-0.6	-0.3	-0.4	-0.4	-1.0	0.0	-0.4	-0.5	-0.6	-0.5	-0.9	-0.5	0.9	-0.7	-0.2	-0.3	0.9	0.5	-0.5
Hair/balding pattern: Pattern 3	0.3	0.5	2.0	-0.5	-0.8	-0.7	-0.8	0.3	0.9	-0.9	-0.0	-0.0	-1.0	-1.4	-0.6	0.1	0.3	0.7	0.2	0.2	0.7	-1.0
Prospective memory result	0.3	0.4	1.3	1.2	0.8	0.4	0.4	0.9	0.8	-0.2	0.5	0.0	0.1	0.8	0.6	0.8	0.5	0.4	0.8	-0.3	-0.3	0.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	0.9	2.1	-1.2	-0.8	-0.3	-0.5	-1.2	0.6	0.6	-1.0	-1.4	-1.1	-1.2	-0.9	1.4	-1.2	-0.4	-0.8	0.7	0.2	-0.7
Arm fat mass (right)	0.3	1.3	2.9	0.7	1.2	1.6	1.7	1.3	0.6	1.0	1.5	0.8	0.7	0.9	-0.9	0.2	1.0	1.0	-0.6	-1.7	-1.2	1.7
Medication: Ventolin 100micrograms inhaler	0.3	0.4	2.2	0.3	0.6	-0.2	0.2	0.1	0.2	-0.9	0.4	0.4	0.4	-0.7	0.7	0.6	0.6	0.4	1.5	1.3	0.5	0.2
Asthma (self-reported)	0.3	0.6	3.3	0.2	0.2	-1.1	-0.5	-1.3	1.2	-0.3	-0.5	0.4	-0.0	-0.9	-1.8	-0.2	-0.9	-0.7	-0.9	0.0	-0.4	-0.4
Hearing aid user	0.3	0.3	1.8	0.2	-0.8	-0.4	-0.2	0.0	0.7	-1.3	-0.6	0.2	0.7	0.2	-0.4	-0.6	-0.5	-0.1	-0.8	-0.0	0.0	-0.4
Number of operations (self-reported)	0.3	0.4	1.9	-0.4	-0.1	-0.6	-0.1	-0.8	1.4	-0.9	-0.4	0.1	0.3	-0.8	-0.6	0.9	-0.9	-0.3	0.1	0.8	0.0	-0.2
Ever had prostate specific antigen (PSA) test	0.3	0.3	1.3	-0.5	-0.2	-0.6	-0.7	-0.6	-0.7	-0.8	-0.4	-0.5	-1.1	-0.2	-0.2	-0.2	-0.3	-0.7	-0.0	-0.5	0.1	-0.6
Irritable Bowel Disease (IBD)	0.2	0.4	1.6	0.5	0.5	0.3	0.0	-0.1	1.3	0.1	0.5	1.1	0.6	0.5	-0.9	1.1	-0.3	-0.5	0.3	0.7	-1.1	0.3
Hearing difficulty/problems: Yes	0.2	0.2	1.9	0.2	0.5	0.1	0.1	-0.0	1.4	-0.4	0.0	0.9	0.1	0.2	-0.2	0.0	-0.2	0.0	-0.9	-0.8	-0.2	0.0
Number of incorrect matches in round	0.2	0.3	1.1	-0.1	0.0	-0.3	0.5	-0.4	-0.6	0.5	-0.4	-0.0	-0.8	-0.8	0.6	-0.1	-0.2	-0.3	0.3	1.1	0.7	0.4
Allergy	0.2	0.5	2.7	0.8	-1.6	0.9	0.1	-0.1	-1.2	0.4	0.2	0.1	1.0	0.9	-0.1	1.1	0.1	-0.3	0.2	0.2	-0.3	0.0
Mouth/teeth dental problems: Dentures	0.2	0.4	1.9	0.3	0.1	-0.5	-0.2	0.2	0.6	1.4	-0.6	-0.0	-1.3	0.2	0.9	-1.3	-0.2	-0.5	-0.3	-0.0	-0.1	-0.1
Pulse wave Arterial Stiffness index	0.2	0.2	0.9	0.3	-0.1	-0.5	-0.5	-0.8	0.1	-0.9	-0.4	-0.1	0.6	0.3	0.3	-0.4	-0.4	-0.8	0.3	0.6	0.2	-0.4
Birth weight	0.2	0.4	1.8	0.7	0.0	0.6	0.6	1.1	0.1	-0.3	0.5	0.1	-1.0	0.0	0.3	-0.6	1.0	1.3	-0.2	-0.7	0.4	0.4
Mouth/teeth dental problems: Loose teeth	0.2	0.2	0.6	-0.7	0.2	-0.0	0.0	0.4	-0.5	-0.3	0.4	-0.5	-0.3	-0.1	-0.8	0.0	0.1	0.3	-0.7	-0.8	-0.5	0.1
Alcohol intake frequency.	0.2	0.5	1.5	-0.0	-0.2	-1.2	-0.9	-0.5	0.5	0.4	-1.0	-1.0	-0.6	-0.8	0.0	0.4	-0.5	0.2	0.3	0.3	1.2	-1.1
Illnesses of father: Heart disease	0.2	0.3	2.6	-0.1	0.3	-0.1	-0.3	0.1	1.6	0.7	-0.1	0.1	0.1	0.3	-0.8	0.1	-0.2	0.6	-1.0	-0.6	-0.0	-0.3
Arm fat mass (left)	0.2	0.9	2.5	0.4	1.1	1.4	1.6	1.2	0.4	0.7	1.2	0.7	0.6	0.6	-0.8	0.3	0.9	1.1	-0.4	-1.3	-0.7	1.5
Average weekly champagne plus white wine intake	0.2	0.3	1.6	1.3	-0.7	0.4	-0.0	0.5	-0.1	0.2	0.3	0.1	1.0	0.9	0.4	-0.1	0.5	-0.2	0.8	-0.2	-0.1	-0.0
Wears glasses or contact lenses	0.2	0.2	1.3	-0.2	-0.6	-0.3	-0.2	-0.1	-0.6	-1.1	0.2	0.8	-0.1	-0.3	-0.1	0.6	0.0	-0.3	0.5	-0.0	-0.3	-0.0
Mother’s age at death	0.2	0.2	0.8	-0.7	-0.4	-0.8	-0.9	-0.5	-0.1	0.2	-0.2	-0.3	0.4	-0.4	0.2	0.4	-0.3	-0.4	0.3	0.9	0.1	-0.7
Financial situation satisfaction	0.2	0.2	0.7	0.4	0.8	0.2	0.4	0.4	-0.2	0.0	0.2	0.6	0.5	0.2	0.4	-0.8	0.7	0.7	0.3	-0.0	0.7	0.3
Medication: Atorvastatin	0.2	0.3	0.9	0.2	0.1	0.7	0.6	0.8	-0.1	-0.1	0.8	0.7	0.2	0.8	0.2	-0.2	0.8	0.9	-0.3	-0.6	-0.2	0.3
Diastolic blood pressure, automated reading	0.2	0.7	2.8	0.6	1.2	-0.0	0.3	0.5	0.0	-0.5	0.5	0.2	0.0	0.5	1.5	-0.0	1.2	1.0	1.7	1.1	0.9	0.5
Supplements: Calcium	0.2	0.3	1.7	0.2	-0.8	-0.3	-0.4	0.2	0.5	1.3	0.2	0.7	-0.2	-0.4	-0.6	0.5	-0.3	-0.0	-0.2	-0.2	-0.5	-0.3
Ulcerative Colitis (UC)	0.1	0.2	0.6	0.2	-0.1	-0.1	-0.3	-0.3	0.7	0.3	0.1	0.3	-0.6	0.1	-0.2	0.8	-0.2	-0.3	0.5	0.8	-0.1	-0.3
BMI	0.1	0.8	3.5	-1.9	-0.5	-0.5	-0.4	-0.8	-1.0	0.3	-0.4	-1.4	0.1	-1.3	-1.4	0.4	-1.0	-1.0	-0.3	-0.1	-0.7	-0.2
Hair Pigment	0.1	2.2	5.8	-1.4	-1.2	-2.0	-1.8	-2.4	0.0	-2.2	-1.8	-1.1	-0.4	-1.8	-0.4	1.0	-2.0	-1.6	-0.1	1.1	0.8	-1.9
Tanning	0.1	1.0	2.3	0.9	1.4	1.0	0.9	1.2	-0.3	0.6	1.0	1.1	0.1	1.4	1.5	-0.4	1.4	1.3	0.9	0.4	0.1	0.9
Weight	0.1	0.3	1.2	-0.2	-0.0	-0.0	0.0	-0.1	1.1	0.3	-0.3	-0.5	0.1	-1.0	-0.9	-0.6	-0.0	0.5	-1.1	-0.6	0.5	-0.2
Hip circumference	0.1	0.6	2.3	0.1	1.0	0.8	1.1	1.0	0.9	0.6	0.9	0.3	0.7	0.1	-0.6	0.4	1.0	1.5	-0.4	-0.8	0.2	0.9
Forced vital capacity (FVC), Best measure	0.1	0.4	2.0	-0.4	-0.3	0.1	-0.0	-0.8	1.1	0.3	-0.4	-0.8	-0.5	-0.5	-0.8	1.4	-0.6	0.0	-0.5	0.5	0.1	-0.2
Breast Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0

Hub : Genes

ASB8

Models

Trait associations