TWAS hub - PFKM

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Brain Cerebellar Hemisphere	0.2930	0.0890	3.7e-04	0.094	NA	0.057	NA	0.052	2.2e-03	NA	1.4e-02	NA	1.9e-02
2	GTEx	Brain Cerebellum	0.2020	0.0640	3.4e-04	0.067	NA	0.028	NA	0.070	4.9e-03	NA	5.2e-02	NA	4.2e-03
3	GTEx	Skin Not Sun Exposed Suprapubic	0.1460	0.0460	3.6e-05	0.055	NA	0.134	NA	0.110	5.4e-04	NA	8.4e-08	NA	1.3e-06
4	GTEx	Skin Sun Exposed Lower leg	0.2240	0.0510	5.3e-11	0.157	NA	0.170	NA	0.164	6.0e-13	NA	5.0e-14	NA	1.7e-13
5	METSIM	Adipose	0.0461	0.0187	3.8e-04	0.007	0.017	0.006	0.018	0.009	2.4e-02	1.1e-03	3.4e-02	7.3e-04	1.4e-02
6	YFS	Blood	0.0252	0.0109	1.2e-03	0.003	0.013	0.008	0.013	0.006	2.9e-02	2.5e-05	8.4e-04	3.6e-05	2.6e-03
7	TCGA	Lung Adenocarcinoma	0.0314	0.0209	5.5e-03	0.008	0.006	0.005	NA	0.006	3.5e-02	5.8e-02	6.7e-02	NA	5.2e-02
8	TCGA	Ovarian Serous Cystadenocarcinoma	0.0980	0.0520	1.7e-04	0.022	0.018	0.014	NA	0.025	1.2e-02	2.1e-02	3.5e-02	NA	7.5e-03
9	TCGA	Prostate Adenocarcinoma	0.0579	0.0316	7.8e-04	0.027	0.033	0.030	NA	0.031	7.1e-04	2.2e-04	3.8e-04	NA	2.8e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Eye problems/disorders: None of the above	8.0	9.3	15.1	1.7	3.6	3.0	2.4	3.4	1.8	3.9	2.8	3.8
Age at first live birth	4.9	8.7	14.5	3.2	3.8	3.5	3.2	3.2	2.1	2.4	1.1	3.0
Qualifications: None of the above	4.4	9.3	17.3	-4.2	-3.6	-3.2	-2.9	-4.0	-1.1	-2.9	-2.2	-2.0
Mouth/teeth dental problems	4.3	6.6	15.4	1.3	2.9	3.4	3.5	1.5	1.0	2.7	0.5	3.9
Qualifications: NVQ or HND or HNC or equivalent	4.3	5.1	11.0	1.4	2.7	2.5	3.0	2.2	-0.1	2.5	0.4	3.3
Supplements: Zinc	4.2	4.6	7.9	2.6	2.8	2.2	1.6	1.6	2.6	1.9	1.7	1.8
Blood Red Count	4.1	39.8	96.4	-4.9	-0.9	-4.9	-8.0	6.0	-9.1	3.8	9.8	-4.0
Multivitamins +/- minerals	4.0	5.1	12.2	1.3	3.0	2.0	0.9	3.5	0.5	2.6	2.1	2.6
Happiness	3.6	4.4	7.4	2.7	2.7	2.2	1.4	2.2	0.4	2.5	2.1	1.5
High blood pressure (siblings)	3.5	5.0	10.0	2.5	2.9	3.2	2.2	0.8	1.8	1.4	0.3	3.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	3.4	4.0	9.2	-1.6	-2.0	-1.1	-1.7	-3.0	-0.9	-2.9	-1.7	-1.9
Bipolar Disorder (2011)	3.2	3.1	9.1	0.6	1.6	0.4	0.1	2.8	0.4	2.7	3.0	0.4
Knee pain experienced in last month	3.1	4.7	14.3	-0.7	-2.0	0.4	1.3	-3.5	1.9	-2.5	-3.8	0.2
Qualifications: nursing, teaching	3.1	4.8	12.4	3.5	3.3	1.0	1.3	2.6	1.3	1.9	1.7	1.4
Loud music exposure frequency	3.0	3.2	9.9	-0.4	-1.7	-1.4	-0.6	-2.0	-0.3	-3.1	-2.7	-1.6
Mineral and other dietary supplements	3.0	4.0	12.1	-0.8	-2.3	-1.8	-1.2	-3.5	-0.1	-2.4	-1.6	-2.2
High blood pressure (mother)	2.8	3.9	15.3	2.4	2.2	1.5	1.7	-0.9	3.9	0.2	-0.6	1.8
Medication: Simvastatin	2.7	3.9	11.1	-0.3	-0.9	-0.5	0.4	-2.9	2.7	-2.7	-3.3	-0.2
Medication: Cholesterol lowering	2.7	4.2	12.5	-0.1	-0.6	0.3	1.4	-2.9	3.5	-1.9	-3.2	0.3
Qualifications: College or University degree	2.7	8.6	18.0	4.1	3.5	2.8	1.9	4.2	1.6	2.8	2.8	1.0
Basal cell carcinoma (self-reported)	2.7	3.2	10.2	1.1	0.9	-0.5	-1.4	2.9	0.7	1.8	3.2	-1.4
Alzheimer’s Disease (in mother)	2.6	3.0	6.5	-1.4	-1.6	-2.5	-2.2	-1.8	-2.1	-0.8	0.3	-1.8
HbA1C	2.6	2.8	8.3	2.6	0.2	1.4	2.2	-0.2	1.0	-1.3	-2.9	0.9
Smoking Status	2.6	6.1	14.9	-3.6	-3.8	-0.5	0.9	-1.7	-2.0	-2.3	-3.9	-0.4
Shortness of breath walking on level ground	2.6	3.2	6.8	0.4	-1.6	-2.0	-2.2	-2.2	-0.2	-2.0	-1.0	-2.6
Sitting height	2.4	16.8	53.0	7.3	7.1	2.2	1.1	1.2	5.9	0.9	2.3	0.5
Alcohol intake versus 10 years previously	2.4	3.6	9.4	1.9	2.8	1.6	0.9	0.7	3.1	1.4	1.7	1.4
Mouth/teeth dental problems: Bleeding gums	2.4	3.1	7.3	0.5	-1.2	-2.6	-2.0	-1.7	0.3	-2.2	-0.3	-2.7
Supplements: Fish oil (including cod liver oil)	2.4	3.1	11.8	0.6	1.8	1.4	0.7	3.4	-0.4	2.1	1.6	1.6
Impedance of leg (right)	2.3	11.0	36.1	1.5	-1.6	-1.4	-1.4	-3.8	3.0	-6.0	-4.8	-2.8
Exposure to tobacco smoke at home	2.3	2.6	7.0	-1.2	-2.6	-1.7	-1.4	-1.4	-0.7	-1.6	-1.1	-1.9
Guilty feelings	2.2	3.3	8.1	-0.4	-2.0	-1.1	-0.9	-2.3	-0.4	-2.8	-2.8	-1.5
High cholesterol (Self-reported)	2.2	3.9	14.5	-0.7	-1.1	-0.4	0.8	-2.7	1.9	-2.7	-3.8	0.3
Cholesterol lowering medication	2.2	3.2	9.0	-1.0	-1.4	-1.5	-1.1	-3.0	0.7	-2.7	-2.2	-1.0
Illnesses of siblings	2.1	3.0	7.2	-1.4	-1.7	-2.4	-1.9	-0.4	-2.1	-0.8	0.5	-2.7
Qualifications: A levels/AS levels or equivalent	2.1	4.6	10.8	3.2	2.5	1.5	1.4	3.3	0.7	1.9	2.2	0.6
Headache pain in last month	2.1	3.7	12.7	3.6	1.9	1.2	0.6	0.9	3.4	1.1	1.2	0.3
Illnesses of father: None of the above (group 1)	2.1	2.6	5.5	-2.1	-1.6	-2.2	-2.0	-0.4	-2.3	-0.4	0.2	-1.4
Alzheimer’s Disease (in father)	2.0	2.2	5.8	0.9	1.5	1.1	0.6	2.0	0.3	2.4	2.0	1.1
Cardiovascular Disease	2.0	6.5	24.7	1.5	0.5	-0.2	-0.0	-5.0	4.2	-2.6	-2.7	-0.4
Impedance of leg (left)	2.0	9.7	32.5	0.8	-2.0	-0.9	-0.9	-3.7	2.3	-5.7	-4.8	-2.4
Medication for cholesterol, blood pressure or diabetes	2.0	3.3	11.9	-0.7	0.1	0.1	-0.5	3.2	-3.4	1.5	2.1	0.1
Chronic bronchitis/emphysema (mother)	2.0	2.3	5.2	-1.7	-2.2	-0.8	-0.1	-2.3	-1.5	-1.1	-2.0	-0.2
Vitamin and mineral supplements	1.9	2.5	7.2	-1.2	-2.2	-0.7	0.2	-2.7	-0.1	-1.7	-2.0	-1.3
Current tobacco smoking	1.9	3.1	9.0	-2.1	-3.0	-0.9	-0.7	-1.5	-1.5	-1.6	-1.9	-1.5
Had menopause	1.9	2.4	4.8	-2.2	-2.2	-1.5	-1.7	-1.7	-1.1	-1.2	-0.9	-0.9
Impedance of arm (right)	1.9	8.7	22.5	2.8	0.3	-2.4	-2.4	-1.7	4.6	-4.7	-2.1	-2.9
Smoking status: Current	1.9	3.0	8.6	-2.1	-2.9	-0.8	-0.7	-1.4	-1.6	-1.6	-1.9	-1.5
Blood Platelet Count	1.8	21.4	92.0	2.8	2.7	4.3	5.3	1.8	9.6	-0.7	-3.8	4.5
Neuroticism	1.8	4.3	10.9	-0.5	-2.4	-1.7	-1.9	-1.7	-0.8	-3.3	-3.0	-1.7
Average weekly spirits intake	1.8	2.3	8.0	-2.8	-1.9	-1.2	-1.1	-0.4	-0.2	-2.0	-1.5	0.1
Townsend deprivation index at recruitment	1.8	2.5	7.6	-1.1	-1.2	0.1	0.5	-2.5	1.2	-1.9	-2.8	0.3
Medication: Ibuprofen (e.g. Nurofen)	1.8	2.3	6.8	2.6	2.5	1.0	0.4	1.6	1.4	0.6	0.8	0.6
Medication: Blood pressure	1.8	3.1	12.9	0.6	0.3	-0.8	0.0	-3.4	3.6	-1.2	-1.2	-0.1
Illnesses of siblings: Diabetes	1.8	2.2	5.1	-0.3	0.3	2.3	2.0	-1.3	-0.2	-0.4	-2.1	2.1
Impedance of whole body	1.8	9.2	28.2	2.8	-0.3	-1.3	-1.3	-2.5	4.2	-5.3	-3.5	-2.6
Schizophrenia vs Biploar Disorder	1.7	2.2	6.3	-1.5	-0.9	0.7	1.5	-1.1	-1.7	-0.5	-2.5	1.8
Leg pain on walking	1.7	2.2	6.7	0.3	-0.2	0.1	1.0	-2.1	2.6	-1.8	-2.0	0.1
Hypertension (Self-reported)	1.7	4.8	21.3	1.8	1.3	-0.1	-0.1	-4.6	3.5	-1.7	-1.1	-0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.7	1.9	4.8	-2.2	-1.3	-1.7	-1.7	-0.1	-2.1	-0.0	0.2	-0.7
Illnesses of father: Heart disease	1.7	2.3	5.9	1.2	1.1	2.4	2.4	0.2	1.0	0.3	-1.1	2.0
Fasting Glucose	1.6	1.9	5.8	-0.1	-0.7	-2.4	-1.9	-0.7	0.9	-1.3	-0.1	-2.0
Hand grip strength (right)	1.6	4.4	11.6	-0.2	1.8	0.2	0.1	3.0	-1.6	3.4	3.4	1.0
Comparative body size at age 10	1.6	4.4	16.9	-3.9	-2.3	-0.9	-0.9	0.2	-4.1	0.9	0.2	0.2
Reason for reducing amount of alcohol drunk: Health precaution	1.6	1.8	3.7	-1.0	-1.6	-1.9	-1.9	-0.9	-0.4	-1.2	-0.5	-1.7
Angina (self-reported)	1.6	2.1	10.9	1.1	0.7	1.2	1.4	-1.0	3.3	0.2	-0.7	1.0
Medication: Aspirin	1.6	2.1	12.7	0.5	1.1	0.3	1.6	-0.1	3.6	0.7	0.0	1.3
Tinnitus: Yes, now most or all of the time	1.6	1.9	5.4	-0.9	0.2	0.5	0.3	2.3	-1.9	1.9	1.6	0.5
Commuting to job workplace: Public transport	1.6	1.9	5.2	-0.1	-1.1	0.1	-0.2	-2.1	1.3	-2.3	-1.7	-1.3
Pain type(s) experienced in last month: Hip pain	1.6	2.0	5.5	-2.3	-2.0	0.1	1.0	-1.1	-1.2	-1.0	-1.8	0.6
Medication: Lisinopril	1.6	2.0	9.2	1.4	1.8	0.0	0.6	-1.1	3.0	0.8	0.6	1.0
Medication: Metformin	1.5	2.1	8.1	0.0	-0.9	1.0	1.5	-1.9	0.4	-1.5	-2.9	0.5
High blood pressure	1.5	4.3	19.8	1.7	1.5	0.2	0.0	-4.5	3.4	-1.3	-0.8	-0.1
Chronic bronchitis/emphysema (father)	1.5	1.7	3.5	-1.6	-0.6	-1.6	-1.6	0.4	-1.9	1.2	1.6	-0.3
Past tobacco smoking	1.5	2.7	7.4	1.4	1.6	1.1	0.5	1.4	1.2	2.6	2.7	0.8
Number of live births	1.5	2.2	3.6	-1.6	-1.6	-1.7	-1.8	0.5	-1.4	0.4	1.6	-1.9
Impedance of arm (left)	1.5	6.7	19.8	3.1	0.7	-1.5	-1.4	-1.2	4.4	-4.1	-2.1	-2.1
Standing height	1.5	15.0	48.4	7.0	5.7	4.8	3.0	0.9	4.4	-0.3	-0.8	1.4
Pulse wave peak to peak time	1.5	1.7	4.2	2.0	1.2	1.0	2.0	-0.6	1.6	0.1	-0.8	1.2
Health satisfaction	1.5	2.0	7.6	0.9	-0.9	-0.7	0.1	-2.8	0.7	-1.8	-1.8	-0.9
Heart disease (mother)	1.5	1.8	4.3	-0.6	0.8	0.3	1.5	-2.1	2.1	-0.3	-1.2	1.7
Medication for cholesterol	1.5	2.3	7.3	-1.1	-1.0	-0.3	-0.9	2.2	-2.7	1.2	1.5	-1.2
Vascular/heart problems diagnosed by doctor	1.5	4.1	16.1	-1.9	-1.5	-0.6	-0.3	4.0	-3.6	1.1	0.8	-0.0
Type 2 Diabetes (T2D) (2012)	1.4	1.6	6.5	2.5	0.5	0.9	0.4	0.2	2.5	-0.2	0.2	-0.8
Height	1.4	26.5	81.0	9.0	7.1	6.8	4.0	1.0	6.3	-0.0	-0.4	1.9
Angina	1.4	1.8	10.1	1.1	0.8	0.9	1.2	-0.9	3.2	0.3	-0.6	0.9
Supplements: Glucosamine	1.4	1.8	5.3	0.4	0.4	2.3	2.1	0.7	-0.8	0.0	-1.6	1.7
Pain all over the body in last month	1.4	1.5	3.7	0.3	1.2	1.3	1.8	0.3	1.3	1.3	0.3	1.9
Mouth/teeth dental problems: Dentures	1.4	2.4	5.1	-1.3	-1.9	-0.9	-2.1	-1.2	-1.4	-1.6	-0.7	-2.3
Chest pain or discomfort	1.4	2.0	7.1	2.6	0.8	1.4	1.0	-0.1	2.7	0.5	0.1	0.4
Age at last live birth	1.4	2.1	6.0	1.3	1.8	1.3	1.2	2.5	0.9	1.4	0.9	1.2
Leg fat-free mass (right)	1.4	7.4	13.7	2.5	3.7	3.5	2.8	2.1	0.6	3.2	1.7	3.0
Friendships satisfaction	1.4	1.8	3.7	1.8	1.9	1.5	0.6	1.3	1.3	1.1	1.2	0.5
Leg predicted mass (right)	1.4	7.6	13.6	2.5	3.7	3.6	2.9	2.1	0.6	3.3	1.7	3.0
Illnesses of father: High blood pressure	1.4	1.8	6.2	2.3	1.9	-0.0	0.0	-0.9	2.5	-0.3	-0.2	0.3
Primary Biliary Cirrhosis	1.3	1.8	3.5	-0.0	-0.1	1.6	1.8	-1.2	1.5	-0.8	-1.9	1.6
Systolic Blood Pressure	1.3	6.7	26.4	1.3	1.5	-1.2	-0.2	-5.1	4.2	-2.6	-2.0	0.3
Hand grip strength (left)	1.3	3.4	8.9	-1.0	1.2	1.0	1.3	2.1	-2.1	3.0	2.2	1.7
Diverticular disease/diverticulitis (self-reported)	1.3	1.6	5.1	0.8	1.6	0.4	0.7	1.0	2.2	1.2	1.6	0.7
Medication: Atenolol	1.3	1.6	8.8	1.4	1.4	-0.4	0.4	-0.5	3.0	0.6	0.8	0.6
Forced expiratory volume in 1-second (FEV1)	1.3	4.5	11.8	-0.0	1.8	3.4	3.2	1.8	0.3	1.6	0.1	3.0
Noisy workplace	1.3	1.6	5.0	-0.6	-0.5	-0.2	0.5	-2.1	0.9	-1.8	-2.2	-0.2
Illnesses of mother	1.3	1.6	6.0	-0.6	-0.8	-0.2	-0.8	2.5	-2.2	-0.1	0.6	-1.1
Hypothyroidism/myxoedema (self-reported)	1.3	2.5	6.5	-0.3	-1.7	-1.0	-0.4	-2.2	1.1	-2.5	-2.1	-1.3
Medication: Omeprazole	1.3	1.5	4.6	-2.1	-1.5	-1.4	-0.9	-1.5	-1.4	0.3	-0.2	-0.2
Pulse rate, automated reading	1.3	4.1	13.4	-0.8	-1.2	-2.8	-3.7	-0.8	-0.5	-1.3	1.0	-3.2
Overall health rating	1.3	2.9	7.2	2.0	-0.5	0.5	0.9	-2.7	2.7	-1.3	-2.0	-0.6
Commuting to job workplace: Car/motor vehicle	1.3	1.5	4.0	-0.6	0.5	-1.2	-1.5	1.6	-1.3	0.9	2.0	-0.4
Osteoarthritis (self-reported)	1.3	1.6	5.2	-2.3	-0.7	-0.4	0.2	-1.8	-0.2	-0.5	-2.0	1.2
Medication: Omeprazole (e.g. Zanprol)	1.3	1.5	3.5	-1.9	-1.6	-1.6	-1.2	-1.1	-1.6	0.4	0.0	-0.4
Bipolar Disorder (2018)	1.2	2.0	6.4	1.1	0.5	-0.8	-1.3	2.5	1.6	0.7	1.8	-1.2
Rheumatoid Arthritis	1.2	1.6	9.4	-1.0	-0.7	0.6	0.1	-0.6	-3.1	-0.7	-1.4	0.3
Schizophrenia (2014)	1.2	2.6	6.6	-0.2	0.7	1.7	1.5	2.4	-1.7	1.5	-0.2	2.6
Leg predicted mass (left)	1.2	6.1	12.8	2.7	3.6	3.2	2.6	1.5	1.2	2.5	1.1	2.6
Hearing difficulty/problems with background noise	1.2	1.9	4.0	1.5	1.6	0.3	0.5	2.0	1.6	1.3	1.9	0.7
Trunk fat-free mass	1.2	6.8	15.3	2.4	3.5	3.9	2.7	1.7	-0.3	3.0	1.3	2.7
Father’s age at death	1.2	1.7	4.4	0.7	0.8	1.1	1.3	2.1	-0.1	1.9	1.4	0.9
Hair/balding pattern: Pattern 3	1.2	1.8	3.3	1.7	1.5	1.8	1.6	1.0	0.4	1.4	0.2	1.5
Trunk predicted mass	1.2	6.9	15.1	2.5	3.6	3.9	2.7	1.7	-0.2	3.1	1.3	2.7
Gout (self-reported)	1.2	1.6	5.4	0.9	1.4	1.6	1.7	0.3	0.3	1.0	0.1	2.3
Neck or shoulder pain in last month	1.2	1.7	6.7	0.1	-1.2	0.3	0.7	-2.0	-0.0	-1.7	-2.6	-0.1
Medication: Ibuprofen	1.2	1.5	3.8	2.0	1.9	1.0	0.6	1.4	1.0	0.6	0.6	0.7
Whole body fat-free mass	1.2	6.9	14.4	2.4	3.6	3.8	2.7	1.7	0.1	3.0	1.3	2.8
Eye problems/disorders: Cataract	1.2	1.4	3.0	-0.4	-1.6	-1.7	-1.2	-0.4	-1.3	-1.0	-0.5	-1.7
Whole body water mass	1.2	6.9	14.0	2.4	3.6	3.7	2.7	1.7	0.2	3.0	1.3	2.8
Ever taken oral contraceptive pill	1.2	1.4	3.6	-0.7	-0.2	-1.7	-1.7	-0.0	0.4	0.6	1.9	-1.3
Crohns Disease (2017)	1.1	2.4	5.3	-2.3	-1.5	-2.1	-1.5	-1.1	0.3	-1.9	-0.9	-1.3
Heel T-Score	1.1	8.8	32.3	-4.7	-0.6	0.8	-0.7	2.5	-5.7	2.7	3.0	0.9
Waist Hip Ratio (WHR)	1.1	4.9	14.3	-1.9	-3.8	-0.3	-0.8	-0.7	-1.4	-2.9	-3.4	-1.8
Medication for hormone replacement therapy	1.1	1.2	2.4	-1.0	-0.5	0.2	0.9	-1.6	1.4	-1.2	-1.5	0.9
Leg fat-free mass (left)	1.1	6.0	12.6	2.7	3.5	3.1	2.5	1.6	1.1	2.6	1.2	2.6
Average weekly fortified wine intake	1.1	1.3	3.0	0.1	1.2	1.1	1.0	1.1	1.4	1.4	1.7	0.6
Diabetes (self-reported)	1.1	1.8	7.0	0.2	-1.3	0.9	1.2	-1.4	0.6	-1.6	-2.6	0.4
Birth weight of first child	1.1	1.9	3.6	1.3	0.3	1.5	1.0	-1.9	1.7	-1.5	-1.8	-0.6
Peak expiratory flow (PEF)	1.1	2.7	6.4	-0.9	0.6	2.5	2.3	1.4	-1.5	1.6	0.4	2.0
Pulse wave reflection index	1.1	1.4	3.0	-1.7	-1.3	-1.1	-1.3	0.3	-1.1	0.2	1.2	-1.4
Medication: Amlodipine	1.1	1.6	6.1	1.3	0.8	-0.4	0.6	-1.8	2.5	-0.6	-1.2	0.7
Arm fat-free mass (right)	1.1	5.6	15.9	2.0	2.9	4.0	3.0	0.9	-0.3	2.4	0.4	2.6
Number of full brothers	1.1	1.4	2.9	-1.0	-1.4	-1.5	-1.3	-0.7	-0.7	-1.1	-0.6	-1.7
Arm predicted mass (right)	1.1	5.5	15.2	1.9	2.9	3.9	3.0	0.7	-0.1	2.4	0.4	2.7
Comparative height size at age 10	1.1	6.0	19.3	2.8	2.6	4.4	3.3	-0.2	-0.0	-0.0	-2.1	2.1
Medication: Aspirin	1.1	1.4	6.7	-0.2	0.8	0.3	1.7	-0.0	2.6	0.7	-0.2	1.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.1	2.4	4.6	-1.2	0.6	1.8	1.9	1.7	0.3	2.1	1.1	2.1
Age started oral contraceptive pill	1.1	1.3	3.0	-0.5	1.4	-0.1	0.6	0.4	1.5	1.3	1.5	1.7
Other serious medical condition/disability diagnosed by doctor	1.0	1.3	2.8	-1.2	-0.5	1.5	1.7	-0.5	-0.2	1.1	-0.7	1.6
Maternal smoking around birth	1.0	1.4	3.4	-1.0	-1.2	-1.3	-1.1	-1.9	-0.5	-1.1	-1.6	-0.4
Worrier / anxious feelings	1.0	2.0	4.4	-0.6	-1.5	-1.9	-2.1	-1.0	-0.4	-1.6	-0.7	-1.8
Forced expiratory volume in 1-second (FEV1), Best measure	1.0	3.3	8.8	0.3	1.5	3.0	2.9	1.4	1.2	1.1	-0.1	2.4
Worry too long after embarrassment	1.0	1.7	5.1	1.2	-0.1	-1.0	-1.1	-0.3	2.3	-1.8	-0.9	-1.5
Wheeze or whistling in the chest in last year	1.0	1.8	3.7	0.7	-1.5	-1.4	-1.8	-1.0	-0.4	-1.6	-0.9	-1.9
Migraine (self-reported)	1.0	1.2	5.1	1.8	0.3	-0.1	-0.2	-0.9	2.3	-0.8	-0.6	-0.7
Illness, injury, bereavement, stress in last 2 years	1.0	1.2	3.5	1.3	1.9	0.7	0.3	0.8	1.7	0.6	0.8	0.7
Smoking status: Previous	1.0	1.6	6.2	-1.1	-0.8	-0.3	0.7	-1.2	-1.1	-1.6	-2.5	0.4
Diabetes diagnosed by doctor	1.0	1.7	6.3	0.2	-1.3	0.4	0.9	-1.7	0.7	-1.5	-2.5	0.0
Alcohol drinker status: Never	1.0	1.2	4.3	-1.8	-0.8	-0.8	-1.1	-0.3	-2.1	0.7	0.4	-0.1
Basal metabolic rate	1.0	5.8	13.2	2.5	3.3	3.6	2.7	1.3	0.4	2.4	0.7	2.6
Alcohol drinker status: Previous	1.0	1.1	2.4	-0.1	1.3	0.8	1.3	0.0	1.6	0.9	0.6	1.4
Crohns Disease (2012)	0.9	1.5	3.6	-1.9	-1.2	-1.5	-0.8	-1.3	-0.1	-1.4	-1.2	-0.8
Lung FVC	0.9	4.7	13.2	-3.6	-0.3	1.6	1.6	1.7	-1.8	2.7	1.7	2.7
Eye problems/disorders: Diabetes related eye disease	0.9	1.0	3.3	-0.0	0.3	1.1	1.4	-1.3	1.8	-0.2	-0.5	0.7
Trunk fat percentage	0.9	3.8	9.0	1.6	0.1	-0.3	0.3	-2.5	3.0	-2.9	-2.8	-0.3
Forced vital capacity (FVC)	0.9	3.4	9.2	0.4	1.9	3.0	2.8	1.1	0.7	1.1	0.0	2.6
Falls in the last year	0.9	1.2	2.7	1.0	-1.1	-0.2	-0.5	-0.7	1.3	-1.5	-1.0	-1.7
Pulse wave Arterial Stiffness index	0.9	1.1	3.4	-1.3	-0.8	-0.5	-1.9	0.5	-1.1	-0.3	0.7	-1.2
Forced vital capacity (FVC), Best measure	0.9	3.1	8.2	0.9	1.8	2.9	2.5	1.1	1.1	1.1	-0.1	2.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.9	1.2	4.2	-0.0	-0.9	-2.0	-1.7	-0.2	-0.7	-0.1	0.8	-1.4
Number of full sisters	0.9	1.1	2.7	-1.5	-0.0	-1.4	-1.6	-0.9	-1.0	-0.2	0.7	-0.5
Mouth/teeth dental problems: Mouth ulcers	0.9	1.4	3.4	-0.4	-1.3	-1.6	-1.8	0.9	0.1	-0.7	0.7	-1.8
Arm fat-free mass (left)	0.9	4.4	11.5	2.0	2.8	3.4	2.5	0.8	0.0	2.1	0.4	2.4
Average weekly beer plus cider intake	0.9	1.3	2.5	-1.2	-1.0	-1.5	-1.6	-1.2	1.0	-1.1	-0.2	-1.1
Risk taking	0.9	1.4	5.9	-0.1	0.2	0.8	-0.4	1.7	-2.4	1.1	1.1	0.0
Fractured/broken bones in last 5 years	0.9	1.2	2.9	0.2	-1.5	-1.0	-0.6	-0.7	0.7	-1.6	-1.0	-1.7
Worry (Nagel 2018)	0.8	1.7	4.0	-0.3	-1.4	-1.1	-1.3	-1.3	-0.5	-1.9	-2.0	-0.7
Blood White Count	0.8	5.6	14.5	-1.8	-1.5	-1.0	0.1	-3.8	-2.7	-2.5	-3.8	1.0
Type 2 Diabetes (T2D) (2018)	0.8	1.6	5.2	1.3	-0.2	0.9	1.3	-1.5	0.8	-1.2	-2.3	0.5
Diabetes (father)	0.8	0.9	2.4	1.4	0.6	1.5	1.5	0.0	0.5	-0.3	-0.9	0.5
Relative age voice broke	0.8	1.2	2.8	1.4	1.0	-0.9	-0.9	0.3	1.4	0.6	1.7	-0.9
Heel bone mineral density (BMD) T-score, automated (left)	0.8	1.9	5.6	-1.7	0.1	1.2	-0.0	1.2	-2.4	1.7	1.4	1.0
Stomach or abdominal pain in last month	0.8	1.0	2.4	0.1	-1.1	-0.3	0.6	-1.3	1.3	-0.9	-1.6	-0.9
Hair/balding pattern: Pattern 2	0.8	1.0	1.8	-1.3	-1.2	-0.8	-0.7	-0.4	-1.3	-0.8	0.1	-1.3
Length of working week for main job	0.8	0.9	2.2	1.1	0.2	-1.2	-0.5	-1.5	0.7	-1.0	-0.9	-1.0
Body fat percentage	0.8	3.1	8.2	0.5	-0.7	-0.4	0.2	-2.7	2.0	-2.7	-2.9	-0.4
Number of children fathered	0.8	0.9	2.9	0.1	-1.0	-0.4	-0.4	1.5	-1.7	0.4	0.7	-1.0
Mouth/teeth dental problems: Loose teeth	0.8	0.9	3.6	-0.3	-0.7	0.6	0.7	-1.9	-1.3	-0.5	-1.1	0.3
Mean time to correctly identify matches	0.8	1.4	3.7	-0.8	-0.2	-1.7	-1.8	0.2	-0.3	-0.0	1.9	-1.5
Suffer from ‘nerves’	0.8	1.2	4.8	0.5	-0.4	0.3	0.8	-1.5	0.5	-1.4	-2.2	0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.8	1.7	4.6	2.1	1.3	2.1	1.2	0.2	1.5	-0.3	-1.0	0.5
Average weekly red wine intake	0.8	1.2	5.1	-0.5	0.3	1.3	1.0	0.1	-2.3	-0.4	-1.4	0.8
Osteoporosis (self-reported)	0.8	1.0	5.7	-1.2	-2.4	-0.2	0.3	-0.0	-1.1	-0.3	-0.8	-0.5
Number of self-reported non-cancer illnesses	0.8	1.4	6.0	0.8	0.3	-0.1	-0.0	-2.4	1.7	-1.1	-1.4	0.3
Miserableness	0.8	1.3	3.1	1.6	1.4	0.7	1.4	0.5	1.1	0.6	-0.4	1.8
Medication: Bendroflumethiazide	0.8	1.2	3.1	0.9	1.5	0.6	0.7	0.4	1.8	1.3	0.9	0.9
Medication: Atorvastatin	0.8	1.0	4.5	0.7	-0.1	0.5	1.6	0.0	2.1	-0.5	-0.9	0.2
Unable to work because of sickness or disability	0.8	1.0	3.8	-0.9	-1.0	1.5	0.5	0.1	-2.0	0.0	-0.9	0.6
Arm predicted mass (left)	0.8	4.2	11.4	1.9	2.6	3.4	2.3	1.0	-0.1	2.0	0.4	2.3
Intelligence (Savage-Jansen 2018)	0.7	2.2	6.5	1.3	2.3	0.1	0.0	1.6	1.2	1.5	2.5	-0.1
Alzheimer’s Disease (including proxy)	0.7	1.0	2.4	-0.7	-0.6	-1.6	-1.5	-0.6	-1.2	0.2	0.7	-1.0
Major Depression (MDD)	0.7	0.9	2.0	-0.6	-0.5	-0.9	-1.4	1.2	-1.2	0.5	0.9	-0.6
Body Mass Index (BMI) (2010)	0.7	1.0	1.4	0.9	1.1	0.8	0.7	1.2	1.2	1.2	1.1	0.7
Hypothyroidism (self reported)	0.7	1.6	3.8	0.2	-1.4	-0.6	-0.6	-1.8	0.9	-1.9	-1.4	-1.5
Ever had hysterectomy (womb removed)	0.7	0.8	2.0	0.6	1.2	0.6	1.0	-1.4	0.7	0.6	0.3	1.0
Severe depression (siblings)	0.7	0.7	2.7	0.3	0.0	-1.3	-1.1	-1.6	0.3	-0.7	-0.2	-0.7
Age when periods started (menarche)	0.7	1.7	5.9	0.7	0.1	-0.8	-1.7	-0.8	2.4	-1.3	-0.1	-1.8
Medication: Levothyroxine sodium	0.7	1.1	3.9	1.0	0.4	-0.4	0.7	-1.9	2.0	-0.7	-0.5	0.1
Trunk fat mass	0.7	2.9	6.6	2.0	0.9	0.8	1.1	-1.9	2.6	-1.8	-2.3	0.4
Financial difficulties in last 2 years	0.7	0.9	2.3	-0.3	-0.7	0.9	1.5	-0.8	1.5	-0.6	-1.1	0.6
Glaucoma (self-reported)	0.7	0.9	3.2	1.0	-0.2	0.3	0.0	-0.1	0.8	-1.6	-1.8	-0.5
Medication: Ventolin 100micrograms inhaler	0.7	0.9	2.9	0.2	0.4	-1.2	-1.7	-0.3	0.7	0.0	1.2	-1.0
Leg fat percentage (right)	0.7	2.6	8.1	-0.3	-1.6	-0.5	0.1	-2.7	0.4	-2.2	-2.8	-0.4
Medication for pain relief, constipation, heartburn	0.7	1.1	5.4	-1.7	-1.2	0.1	0.4	-0.6	-2.3	-0.2	-0.4	-0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.8	2.0	-1.4	-1.0	-1.3	-0.7	0.0	-0.9	-0.7	-0.8	0.0
Loneliness, isolation	0.7	0.9	2.8	0.5	-0.3	1.3	1.0	-0.6	-1.2	-0.4	-1.7	0.7
Medication: Blood pressure	0.7	1.4	3.4	1.8	1.7	0.4	0.5	-1.2	1.9	0.5	0.7	0.5
Ever smoked	0.7	1.2	4.1	-1.1	-1.3	0.1	-0.0	0.0	-0.9	-1.7	-2.0	-0.4
Leg fat percentage (left)	0.7	2.5	7.9	-0.8	-1.7	-0.1	0.4	-2.7	-0.1	-1.9	-2.8	-0.1
Number of operations (self-reported)	0.7	1.0	1.9	-0.2	0.7	1.0	1.4	1.1	1.3	0.9	0.3	1.4
Diastolic blood pressure, automated reading	0.7	2.0	5.2	0.2	-0.7	-1.8	-2.3	-1.8	-0.4	-0.9	0.8	-2.1
Ever depressed for a whole week	0.7	0.8	2.4	1.5	0.5	1.2	1.5	0.2	0.6	0.2	-0.6	0.6
Neuroticism (Nagel 2018)	0.6	1.5	4.9	0.4	-0.9	-0.7	-1.1	-0.9	-0.1	-2.2	-2.1	-0.5
Schizophrenia (2018)	0.6	1.3	3.1	-0.5	-0.1	1.5	1.1	1.2	-1.6	0.7	-0.8	1.8
Relative age of first facial hair	0.6	1.2	3.3	-0.3	-0.5	-1.8	-1.6	-0.4	0.8	-0.5	0.8	-1.7
Systolic blood pressure, automated reading	0.6	1.6	5.5	1.1	1.2	-0.7	-0.6	-2.4	2.0	-1.1	-0.2	0.1
Fed-up feelings	0.6	1.0	2.7	1.2	0.3	1.6	1.1	0.0	-0.1	-0.0	-1.3	1.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.8	2.5	-0.4	-0.9	0.3	1.2	-0.9	-0.3	0.1	-1.6	1.2
Taking other prescription medications	0.6	0.9	4.2	-1.1	-0.9	-0.4	-0.0	-2.0	-0.0	-0.4	-1.1	0.2
Number of incorrect matches in round	0.6	1.0	3.0	0.0	-0.5	-0.5	-1.7	0.9	-0.8	-1.1	0.4	-1.6
Pulse rate	0.6	1.0	3.7	-0.2	-0.8	-0.1	-1.9	0.5	-1.2	-0.6	0.3	-1.5
Medication: Lansoprazole	0.6	0.7	2.0	-0.6	-0.9	-1.4	-0.4	-1.3	0.5	-0.7	-0.8	-0.5
Breastfed as a baby	0.6	0.8	2.5	-0.7	-0.7	1.1	1.6	0.8	-0.6	-0.1	-0.7	0.8
Seen doctor (GP) for nerves, anxiety, tension or depression	0.6	0.9	2.0	-1.2	-1.1	-0.5	-0.1	-1.0	-1.4	-0.8	-1.2	0.3
Ever highly irritable/argumentative for 2 days	0.6	0.7	2.5	0.6	0.1	-0.3	0.4	-1.6	-1.3	-0.4	-1.2	0.3
Medication: Paracetamol	0.6	0.9	2.6	1.6	1.0	-0.0	-0.9	0.9	1.3	0.6	1.0	-0.1
Alcohol intake frequency.	0.6	1.5	3.3	0.8	1.1	1.8	1.3	0.3	0.4	1.6	0.7	1.8
Had major operations	0.6	0.7	1.9	-0.9	-0.7	-0.5	0.3	-1.4	1.2	-0.6	-1.1	0.3
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.6	1.3	0.5	0.5	0.3	1.2	0.9	0.5	1.1	1.1	0.1
Average weekly champagne plus white wine intake	0.6	0.8	2.9	-0.2	-0.2	-1.4	-1.7	0.2	-0.5	-0.1	0.8	-1.1
Wears glasses or contact lenses	0.6	0.7	2.7	-0.6	-0.5	-1.2	-1.1	-0.4	-1.6	0.1	0.5	-0.2
Myopia	0.6	0.9	1.9	1.4	0.8	1.0	0.9	0.4	1.4	-0.2	-1.1	0.8
Ovarian Cancer	0.5	0.6	1.8	1.3	0.4	-0.6	-0.9	0.8	0.3	0.4	1.2	-0.6
Coronary Artery Disease (CAD)	0.5	0.6	2.5	0.4	0.3	0.8	1.1	-0.5	1.6	-0.4	-0.7	0.2
HDL Cholesterol	0.5	0.8	2.1	0.5	-1.1	0.3	0.2	-0.9	0.3	-1.4	-1.4	-0.8
Ever used hormone-replacement therapy (HRT)	0.5	0.6	2.2	-0.4	-1.5	-0.2	-0.4	-0.5	0.3	-1.1	-0.6	-1.0
Medication: Co-codamol	0.5	0.6	2.3	0.7	1.5	0.4	-0.3	-0.2	0.8	0.2	0.1	1.2
Diabetes (mother)	0.5	0.6	2.9	-0.2	-0.0	-0.6	-0.3	-1.7	0.5	-1.0	-0.9	0.0
Bilateral oophorectomy (both ovaries removed)	0.5	0.6	2.0	0.9	0.4	-0.0	0.0	0.2	1.2	0.3	1.4	-0.6
Qualifications: CSEs or equivalent	0.5	0.6	1.4	0.3	0.6	1.2	0.2	0.3	1.1	-0.6	-1.0	1.1
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.2	2.9	-1.7	-0.0	1.0	0.1	1.0	-1.7	1.2	0.9	0.9
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	1.5	1.2	0.2	-0.2	-0.7	1.0	0.3	0.8	0.9	-0.6
Fluid intelligence score	0.5	1.1	3.0	0.2	-0.1	-0.9	-1.5	1.0	0.1	0.2	1.7	-1.6
Weight	0.5	2.6	5.9	2.0	1.8	2.4	2.2	-0.3	1.0	0.5	-0.9	1.7
Hip circumference	0.5	2.3	4.9	2.2	1.7	1.8	1.7	-0.7	1.7	-0.2	-1.1	1.4
Medication: Allopurinol	0.5	0.7	2.5	-0.2	0.8	0.5	0.4	0.5	-0.1	1.1	0.8	1.6
Medication: Seretide 50 evohaler	0.5	0.6	2.0	0.1	-0.4	0.6	0.2	-1.0	-0.4	-1.3	-1.4	-0.1
Whole body fat mass	0.5	2.2	5.0	1.4	0.7	0.9	1.2	-1.9	2.0	-1.4	-2.2	0.7
Long-standing illness, disability or infirmity	0.5	0.8	2.8	-0.5	-0.8	-0.3	0.8	-1.7	1.2	-0.1	-1.1	0.5
Ever had bowel cancer screening	0.5	0.6	2.0	0.2	0.2	-1.1	-0.5	-0.8	1.4	-0.8	0.1	-0.6
Medication: Gliclazide	0.5	0.6	2.2	0.2	-1.0	0.4	0.2	-1.0	-0.3	-0.6	-1.5	-0.4
Hearing aid user	0.5	0.6	2.2	0.7	0.6	1.5	1.0	0.3	0.6	0.3	-0.6	0.8
Eye problems/disorders: Glaucoma	0.5	0.6	2.1	0.6	-0.6	-0.1	-0.4	-0.2	0.4	-1.4	-1.4	-0.7
Medication: Paracetamol	0.5	0.7	1.7	0.7	0.7	-0.4	-1.1	1.0	0.5	0.9	1.3	0.1
Pain experienced in last month	0.5	0.8	2.6	-0.5	0.6	0.1	-0.5	0.8	-1.5	0.7	1.6	-0.0
Leg fat mass (left)	0.5	1.8	6.3	0.3	-0.3	1.0	1.4	-2.2	0.6	-1.2	-2.5	0.7
Bipolar Disorder or Schizophrenia	0.4	1.0	6.5	0.3	0.2	0.8	0.0	2.5	-0.3	1.0	0.5	0.6
Irritable Bowel Disease (IBD)	0.4	0.9	4.0	-2.0	-0.7	-1.4	-0.9	-0.1	0.5	-0.5	0.1	-0.3
Verbal and Numeric Reasoning (VNR)	0.4	1.1	2.6	0.6	1.5	-0.0	-0.0	1.0	1.6	0.9	1.6	-0.1
Mean Putamen Volume	0.4	0.4	0.9	0.9	0.9	-0.8	-0.9	0.3	-0.0	-0.2	0.4	-0.5
LDL Cholesterol	0.4	0.6	1.6	-0.1	-0.5	0.4	1.0	-0.8	1.0	-0.7	-1.3	0.4
Blood Eosinophil Count	0.4	3.3	14.8	-0.9	-0.8	1.9	1.4	-1.4	-1.2	-1.6	-3.9	1.5
Number of treatments/medications taken	0.4	0.8	3.3	0.5	0.3	-0.8	-0.8	-1.5	1.8	-0.1	-0.0	-0.2
Sensitivity / hurt feelings	0.4	0.7	1.9	0.4	-0.4	-1.0	-1.2	0.4	-0.1	-1.4	-1.0	-0.8
Serious illness, injury or assault to yourself	0.4	0.5	1.5	1.2	0.9	1.1	0.2	-0.1	0.2	0.7	0.3	0.3
Nervous feelings	0.4	0.7	1.7	0.0	-0.9	-1.2	-1.3	0.1	0.3	-1.0	-0.5	-0.9
Had other major operations	0.4	0.4	1.4	-0.4	-0.0	0.2	0.5	0.8	0.3	1.2	0.6	1.0
Heart attack	0.4	0.5	2.3	-1.5	-1.0	-0.3	0.2	-0.1	0.4	0.9	0.3	0.3
Arm fat percentage (right)	0.4	1.4	3.2	-0.1	-1.0	-1.1	-0.4	-1.7	1.0	-1.8	-1.8	-0.3
Time employed in main current job	0.4	0.5	1.6	0.9	1.2	-0.5	-0.2	-0.2	1.1	0.0	0.3	0.2
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.7	3.2	1.2	0.3	-0.3	-0.4	-0.5	1.8	0.6	0.7	-0.4
Lung cancer (father)	0.4	0.5	1.4	1.0	0.7	-0.3	-1.2	-0.0	1.0	0.3	0.7	-0.2
Qualifications: O levels/GCSEs or equivalent	0.4	0.7	3.3	1.8	0.5	0.4	0.7	0.7	0.2	0.9	0.9	-0.2
Blood clot in the leg (DVT)	0.4	0.5	2.4	0.5	0.0	0.3	-0.1	-0.5	0.8	-1.6	-0.9	-0.7
Birth weight	0.4	0.9	2.7	1.6	1.0	1.0	1.1	-0.8	0.4	-0.2	-0.9	0.4
Emphysema/chronic bronchitis	0.4	0.5	1.0	0.6	-0.5	-0.2	-0.8	-1.0	0.3	-0.9	-0.7	-0.8
Leg fat mass (right)	0.4	1.6	5.6	0.5	-0.2	0.6	1.1	-2.1	0.9	-1.3	-2.4	0.5
Supplements: Vitamin C	0.4	0.5	2.0	0.5	0.2	0.4	-0.5	1.4	-1.4	0.2	0.2	0.1
Breast cancer (self-reported)	0.4	0.4	1.6	-1.3	-0.0	0.2	0.2	0.1	-0.3	1.1	0.6	0.6
Heart attack/myocardial infarction (self-reported)	0.4	0.5	2.3	-1.5	-1.0	-0.2	0.3	-0.0	0.3	1.1	0.3	0.3
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	2.6	0.1	-0.2	0.3	-0.4	-0.4	0.5	-1.6	-0.9	-0.7
Depressed Affect (Nagel 2018)	0.3	0.7	2.1	1.0	0.6	0.5	0.6	-0.2	0.1	-0.6	-1.4	1.3
Depression (Nagel 2018)	0.3	0.4	1.8	-0.5	-0.2	-0.1	0.4	-0.4	-0.7	0.0	-1.1	1.3
Reaction Time	0.3	0.5	1.8	-1.0	-0.2	-1.3	-1.0	-0.1	-0.1	-0.2	0.8	-0.5
Lupus	0.3	0.5	2.3	-1.1	-0.8	-0.2	-0.3	0.1	-1.5	0.4	0.2	-0.0
Ulcerative Colitis	0.3	0.5	1.3	-1.1	0.3	0.7	0.6	-0.1	1.0	-0.1	-0.4	1.1
Respiratory disease	0.3	0.6	4.0	-0.1	0.4	-0.3	-0.6	-2.0	-0.4	-0.4	-0.6	0.1
Lung FEV1/FVC ratio	0.3	1.4	3.8	-1.3	-1.0	0.4	0.6	1.9	-1.8	0.9	1.2	-0.4
Hearing difficulty/problems: Yes	0.3	0.5	0.8	0.7	0.1	0.8	0.8	0.8	0.7	-0.8	-0.9	0.4
Tinnitus: Yes, but not now, but have in the past	0.3	0.4	1.1	-0.1	-0.4	0.4	0.3	0.9	-0.8	0.2	-0.3	1.1
Waist circumference	0.3	1.2	5.5	-0.1	-1.1	0.9	0.7	-1.1	-0.3	-1.1	-2.3	0.2
Alcohol usually taken with meals	0.3	0.4	2.0	0.2	-0.2	0.7	0.6	0.6	-1.4	0.4	0.3	-0.6
Neuroticism score	0.3	0.5	2.2	0.7	-0.3	-0.2	-0.4	-0.2	0.3	-1.3	-1.5	-0.1
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.3	0.8	-0.3	-0.8	0.1	0.7	-0.1	-0.5	-0.4	-0.9	0.4
Tense / ‘highly strung’	0.3	0.5	1.9	1.0	-0.2	0.1	-0.2	0.3	-0.5	-1.1	-1.4	-0.1
Hair/balding pattern: Pattern 4	0.3	0.8	2.5	0.6	-0.1	-1.0	-1.1	-0.5	1.6	-1.2	-0.4	-0.8
Exposure to tobacco smoke outside home	0.3	0.4	0.7	-0.4	-0.8	-0.8	0.1	-0.8	-0.8	0.3	-0.5	0.7
Family relationship satisfaction	0.3	0.4	1.9	-0.1	-0.4	0.5	0.5	-0.7	-1.4	-0.3	-0.7	-0.3
Mood swings	0.3	0.6	1.4	0.8	0.9	0.3	0.5	-0.7	1.2	-0.2	-0.8	1.0
Commuting to job workplace: Walk	0.3	0.3	1.6	0.5	-0.1	-0.3	0.5	0.0	1.3	-0.4	-0.3	-0.2
Financial situation satisfaction	0.3	0.4	2.1	1.5	0.6	0.6	0.3	-0.3	0.8	0.0	0.0	-0.3
Commuting to job workplace: Cycle	0.3	0.3	1.2	0.0	0.8	-0.1	0.1	0.1	1.1	0.5	0.8	0.0
Supplements: Calcium	0.3	0.3	1.2	-0.2	0.1	0.4	0.5	0.5	-0.4	0.5	-0.3	1.1
Heart disease (siblings)	0.3	0.4	1.9	0.7	0.6	-0.4	-0.2	-0.3	1.4	0.1	-0.1	0.5
Ulcerative Colitis (UC)	0.2	0.3	0.9	-0.9	0.1	-0.4	-0.4	0.8	0.5	0.5	0.7	0.3
Age at First Birth	0.2	0.3	1.6	-1.3	-0.1	-0.1	-0.5	0.3	-0.8	0.0	0.5	-0.1
Neuroticism (2016)	0.2	0.3	1.4	1.2	0.2	0.0	0.1	-0.1	-0.4	-0.3	-0.9	0.6
Triglycerides	0.2	0.3	1.4	-1.0	-0.3	-1.2	-0.4	-0.4	-0.4	0.1	0.3	0.1
Chronotype (morning person)	0.2	0.6	2.4	-0.3	0.8	0.6	0.2	-0.8	-0.6	0.2	-0.6	1.6
Frequency of depressed mood in last 2 weeks	0.2	0.2	0.9	-0.2	-0.1	0.5	0.6	-0.2	0.0	0.3	-0.7	0.9
Body mass index (BMI)	0.2	0.7	1.4	-1.2	-0.8	0.2	0.8	-0.8	-1.1	0.6	-0.6	1.0
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	1.3	0.6	-0.7	-0.1	0.1	-0.6	0.1	-0.4	-1.2	-0.3
Allergy	0.2	0.4	0.7	-0.5	0.5	-0.2	0.1	0.8	0.1	0.9	0.7	0.8
Medication: Ramipril	0.2	0.3	1.3	1.1	0.6	0.5	0.0	-0.3	0.8	0.1	0.2	-0.3
Asthma	0.2	0.4	1.8	-0.6	-0.2	0.1	-0.0	-0.8	-1.3	-0.4	-0.7	0.2
Depression (self-reported)	0.2	0.3	0.6	0.5	0.6	0.7	0.1	-0.2	0.8	-0.4	-0.7	0.5
Prospective memory result	0.2	0.2	0.8	-0.7	-0.7	-0.9	-0.6	0.2	0.1	-0.1	0.2	-0.2
Arm fat mass (right)	0.2	0.7	2.2	0.4	0.0	0.1	0.4	-1.4	0.7	-0.9	-1.5	0.4
Arm fat percentage (left)	0.2	0.8	2.4	0.2	-0.6	-0.5	0.1	-1.4	1.0	-1.2	-1.6	0.1
Handedness (chirality/laterality): Left-handed	0.2	0.2	0.7	-0.3	-0.7	0.5	0.1	0.7	-0.8	0.3	0.3	-0.2
Back pain experienced in last month	0.2	0.3	1.5	-1.2	-0.6	-0.0	-0.1	0.4	-0.2	0.2	-0.5	0.4
Asthma (self-reported)	0.2	0.3	1.5	-0.2	0.1	0.3	0.0	-0.8	-1.2	-0.2	-0.5	0.4
Arm fat mass (left)	0.2	0.7	1.5	0.9	0.6	0.6	0.8	-0.9	1.0	-0.4	-1.2	0.9
Irritability	0.2	0.3	0.5	-0.5	-0.4	0.7	0.7	0.2	-0.3	-0.1	-0.7	0.6
Pack years of smoking	0.2	0.3	1.3	-0.3	-0.7	0.2	-0.4	0.4	-0.4	1.1	0.6	-0.3
BMI	0.1	0.5	2.0	-1.4	-0.5	-0.7	-0.2	-0.8	-0.8	0.4	-0.0	0.4
Allergy or Eczema	0.1	0.3	1.0	0.5	0.1	-0.2	-0.2	0.2	0.8	0.7	1.0	-0.4
Hair Pigment	0.1	1.7	4.0	-0.3	0.6	1.4	1.5	0.8	0.3	2.0	1.4	1.9
Tanning	0.1	0.8	2.2	0.7	0.2	-1.3	-1.5	-0.2	0.5	-0.5	-0.2	-1.4
Pack years adult smoking proportion	0.1	0.2	0.6	-0.4	-0.8	0.3	-0.3	0.2	-0.3	0.7	0.2	-0.2
Hayfever, allergic rhinitis or eczema	0.1	0.2	0.8	0.9	-0.2	0.4	0.3	0.2	0.6	0.1	0.2	-0.5
Hayfever/allergic rhinitis (self-reported)	0.1	0.1	0.3	0.5	0.2	0.5	0.1	-0.0	-0.2	0.5	0.3	-0.1
Mother’s age at death	0.1	0.2	0.4	-0.5	0.0	0.4	-0.6	-0.1	-0.6	0.1	0.5	-0.3
Ever had prostate specific antigen (PSA) test	0.1	0.1	0.3	-0.1	-0.3	-0.4	-0.2	0.4	-0.3	0.4	0.6	-0.1
Breast Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0

Hub : Genes

PFKM

Models

Trait associations