Best TWAS P=3.66e-09 · Best GWAS P=3.74e-31 conditioned to 4.57e-23
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | KIAA0247 | 0.15 | 0.02 | enet | 21 | 0.02 | 1.8e-02 | -5.63 | -5.7 | 9.1e-09 | 0.01 | 0.05 | 0.74 | TRUE |
| 2 | GTEx | Artery Tibial | SMOC1 | 0.33 | 0.32 | lasso | 10 | 0.33 | 3.0e-26 | -5.13 | -5.4 | 8.6e-08 | -0.05 | 0.22 | 0.78 | TRUE |
| 3 | METSIM | Adipose | ACTN1 | 0.05 | 0.00 | blup | 667 | 0.01 | 3.0e-03 | 3.91 | 5.3 | 1.2e-07 | -0.02 | 0.72 | 0.05 | FALSE |
| 4 | The Cancer Genome Atlas | Breast Invasive Carcinoma | VTI1B | 0.02 | 0.00 | blup | 39 | 0.01 | 7.3e-03 | 2.74 | 5.6 | 1.8e-08 | 0.46 | 0.01 | 0.55 | FALSE |
| 5 | The Cancer Genome Atlas | Lung Adenocarcinoma | RAD51L1 | 0.04 | 0.00 | blup | 471 | 0.00 | 9.9e-02 | 0.31 | 5.9 | 3.7e-09 | 0.61 | 0.07 | 0.23 | TRUE |
| 6 | The Cancer Genome Atlas | Soft Tissue Sarcoma | SMOC1 | 0.07 | 0.00 | blup | 188 | 0.02 | 1.9e-02 | 5.10 | -5.2 | 1.8e-07 | -0.02 | 0.04 | 0.51 | FALSE |
| 7 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | RDH12 | 0.12 | 0.00 | enet | 14 | 0.04 | 1.4e-02 | -1.14 | 5.7 | 1.3e-08 | 0.34 | 0.01 | 0.53 | FALSE |