[Hub]/) : Traits : Blood Red Count :

chr14:63,623,678-66,266,677

Best TWAS P=2.79e-27 · Best GWAS P=2.82e-37 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex MAX 0.15 0.16 lasso 2 0.16 1.2e-18 -11.2 10.8 2.8e-27 -0.55 1.00 0.00 TRUE
2 CommonMind Brain Pre-frontal Cortex SPTB 0.06 0.05 bslmm 528 0.05 9.5e-07 -1.3 7.2 6.0e-13 -0.30 0.84 0.07 FALSE
3 GTEx Adipose Subcutaneous RAB15 0.48 0.07 enet 82 0.18 5.7e-15 -2.2 -5.6 1.8e-08 0.35 1.00 0.00 FALSE
4 GTEx Brain Nucleus accumbens basal ganglia MTHFD1 0.27 0.10 lasso 3 0.14 1.3e-04 -5.1 5.3 1.3e-07 -0.02 0.18 0.31 FALSE
5 GTEx Cells EBV-transformed lymphocytes MTHFD1 0.20 0.03 lasso 6 0.09 5.6e-04 -2.6 -6.9 4.2e-12 0.00 0.02 0.84 TRUE
6 GTEx Cells Transformed fibroblasts RAB15 0.64 0.08 enet 41 0.33 1.3e-25 -5.7 -7.0 1.9e-12 0.46 1.00 0.00 FALSE
7 GTEx Colon Transverse MTHFD1 0.20 0.01 enet 49 0.02 6.2e-02 -3.3 6.2 4.9e-10 -0.20 0.20 0.14 TRUE
8 GTEx Esophagus Mucosa MTHFD1 0.09 0.00 enet 25 0.02 3.2e-02 5.9 5.6 2.2e-08 -0.06 0.10 0.07 FALSE
9 GTEx Esophagus Muscularis RAB15 0.35 0.06 enet 23 0.17 1.2e-10 -5.7 -5.1 2.8e-07 0.56 0.84 0.16 TRUE
10 GTEx Heart Left Ventricle SYNE2 0.20 0.14 lasso 5 0.09 1.6e-05 5.4 -5.6 1.7e-08 -0.03 0.27 0.70 FALSE
11 GTEx Muscle Skeletal FNTB 0.05 0.02 lasso 6 0.01 5.8e-02 -9.9 9.2 3.0e-20 -0.53 0.25 0.46 FALSE
12 GTEx Nerve Tibial RAB15 0.35 0.15 enet 68 0.18 4.7e-13 -8.2 -8.0 9.2e-16 0.43 1.00 0.00 FALSE
13 GTEx Nerve Tibial CTD-2555O16.4 0.09 0.06 lasso 6 0.04 7.7e-04 6.9 5.3 1.3e-07 0.02 0.07 0.80 FALSE
14 GTEx Ovary CTD-2555O16.2 0.23 0.10 enet 26 0.18 2.7e-05 -2.1 7.4 1.1e-13 0.02 0.07 0.83 FALSE
15 GTEx Pituitary RAB15 0.32 0.03 enet 16 0.10 1.9e-03 -10.8 -9.6 5.4e-22 0.63 0.15 0.48 TRUE
16 GTEx Testis RAB15 0.23 0.16 lasso 5 0.13 2.8e-06 -5.7 -6.2 4.5e-10 0.59 0.18 0.74 FALSE
17 GTEx Testis PPP1R36 0.29 0.25 enet 17 0.28 1.1e-12 3.6 -6.2 5.7e-10 0.36 1.00 0.00 FALSE
18 GTEx Thyroid RAB15 0.26 0.04 enet 52 0.08 1.5e-06 -5.7 -7.0 2.1e-12 0.41 0.90 0.08 TRUE
19 GTEx Whole Blood RAB15 0.34 0.03 lasso 6 0.05 2.8e-05 -2.2 -6.6 5.7e-11 0.34 0.68 0.06 FALSE
20 METSIM Adipose ESR2 0.03 0.02 enet 8 0.03 2.5e-05 6.2 -6.4 1.2e-10 -0.09 0.64 0.30 FALSE
21 METSIM Adipose RAB15 0.10 0.04 enet 22 0.08 3.8e-12 -9.2 -7.8 4.4e-15 0.56 1.00 0.00 FALSE
22 NTR Blood ESR2 0.03 0.01 bslmm 507 0.01 5.5e-04 5.1 6.7 1.6e-11 0.06 0.00 1.00 FALSE
23 NTR Blood SYNE2 0.08 0.08 lasso 5 0.08 9.9e-25 6.2 -6.9 4.3e-12 -0.04 1.00 0.00 TRUE
24 YFS Blood MAX 0.04 0.02 lasso 4 0.02 2.8e-06 -10.2 10.3 7.6e-25 -0.66 0.68 0.26 FALSE
25 The Cancer Genome Atlas Bladder Urothelial Carcinoma FNTB 0.10 0.03 blup 107 0.07 7.9e-07 -2.1 5.4 6.4e-08 -0.36 0.84 0.02 FALSE
26 The Cancer Genome Atlas Breast Invasive Carcinoma FNTB 0.02 0.03 enet 8 0.03 2.0e-07 -3.5 5.5 3.3e-08 -0.43 0.98 0.01 FALSE
27 The Cancer Genome Atlas Breast Invasive Carcinoma RAB15 0.02 0.01 blup 49 0.02 6.7e-05 -3.6 -6.4 1.2e-10 0.57 0.36 0.36 FALSE
28 The Cancer Genome Atlas Esophageal Carcinoma FNTB 0.09 0.05 lasso 3 0.04 2.6e-02 -8.6 6.9 5.3e-12 -0.61 0.06 0.22 FALSE
29 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma ESR2 0.04 0.01 blup 88 0.03 1.1e-04 6.9 7.1 8.8e-13 0.04 0.04 0.94 TRUE
30 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma FNTB 0.06 0.02 blup 106 0.04 3.7e-05 -1.7 7.9 3.0e-15 -0.51 0.16 0.37 FALSE
31 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma RAB15 0.03 0.00 blup 49 0.01 1.8e-02 -8.1 -6.8 1.3e-11 0.59 0.05 0.64 FALSE
32 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ESR2 0.11 0.03 blup 88 0.06 6.9e-07 -11.1 10.6 3.7e-26 0.02 0.00 0.99 TRUE
33 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma RAB15 0.14 0.07 enet 15 0.09 5.5e-10 -8.2 -7.9 4.1e-15 0.56 0.66 0.34 FALSE
34 The Cancer Genome Atlas Brain Lower Grade Glioma RAB15 0.04 0.05 blup 49 0.06 2.5e-07 -3.6 -6.6 4.9e-11 0.62 0.44 0.53 FALSE
35 The Cancer Genome Atlas Lung Adenocarcinoma RAB15 0.04 0.01 enet 5 0.03 1.9e-04 -12.3 -9.6 6.3e-22 0.82 0.00 0.97 TRUE
36 The Cancer Genome Atlas Lung Squamous Cell Carcinoma ESR2 0.02 0.00 blup 88 0.01 2.1e-02 -11.1 9.2 2.7e-20 -0.01 0.01 0.88 FALSE
37 The Cancer Genome Atlas Prostate Adenocarcinoma RAB15 0.04 0.00 blup 49 0.01 6.9e-02 -8.2 -6.7 1.7e-11 0.51 0.11 0.11 FALSE
38 The Cancer Genome Atlas Soft Tissue Sarcoma FNTB 0.05 0.04 blup 107 0.03 6.5e-03 -2.0 6.1 1.4e-09 -0.51 0.22 0.15 FALSE
39 The Cancer Genome Atlas Thyroid Carcinoma ESR2 0.05 0.05 lasso 3 0.05 9.6e-06 6.2 6.4 1.9e-10 0.04 0.28 0.64 FALSE
40 The Cancer Genome Atlas Thyroid Carcinoma FNTB 0.14 0.06 enet 18 0.14 1.4e-13 -1.7 5.9 2.7e-09 -0.47 0.99 0.01 FALSE