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chr20:46,840,115-50,071,258

Best TWAS P=2.37e-35 · Best GWAS P=8.68e-61 conditioned to 4.19e-18

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
8	GTEx	Colon Transverse	FAM65C	0.16	0.06	lasso	3	0.04	5.7e-03	12.048	-12.4	2.4e-35	0.40	0.28	0.06	TRUE
11	GTEx	Nerve Tibial	TMEM189	0.18	0.00	enet	36	0.05	3.1e-04	-1.592	10.2	2.9e-24	-0.35	0.08	0.52	TRUE
14	METSIM	Adipose	PARD6B	0.03	0.00	bslmm	494	0.01	5.1e-02	6.375	-9.6	9.9e-22	0.40	0.04	0.37	TRUE
6	GTEx	Cells Transformed fibroblasts	PTPN1	0.11	0.00	lasso	4	0.00	4.5e-01	-6.984	-7.0	3.5e-12	0.16	0.05	0.05	TRUE
10	GTEx	Nerve Tibial	PTPN1	0.11	0.01	lasso	3	0.01	5.4e-02	0.097	6.4	2.0e-10	-0.28	0.10	0.24	TRUE
7	GTEx	Colon Sigmoid	ARFGEF2	0.15	0.12	lasso	1	0.07	2.3e-03	5.987	-6.0	2.1e-09	-0.10	0.01	0.93	TRUE
13	GTEx	Testis	RP4-530I15.9	0.36	0.42	lasso	1	0.42	3.3e-20	11.697	11.7	1.3e-31	-0.51	1.00	0.00	FALSE
3	GTEx	Adipose Subcutaneous	UBE2V1	0.11	0.05	enet	19	0.06	8.6e-06	2.307	-6.3	2.8e-10	0.14	0.24	0.06	FALSE
9	GTEx	Nerve Tibial	CSE1L	0.12	0.01	lasso	10	0.03	5.7e-03	-4.237	-5.9	3.0e-09	-0.09	0.19	0.24	FALSE
15	YFS	Blood	ZNFX1	0.06	0.05	lasso	3	0.05	1.4e-16	5.769	-5.8	5.8e-09	-0.07	0.01	0.99	FALSE
1	CommonMind	Brain Pre-frontal Cortex	CSE1L	0.08	0.07	bslmm	503	0.05	1.7e-06	-4.654	-5.5	3.1e-08	-0.10	0.53	0.47	FALSE
5	GTEx	Brain Frontal Cortex BA9	RP11-112L6.4	0.29	0.25	lasso	5	0.22	1.8e-06	1.975	5.5	3.1e-08	-0.20	0.43	0.05	FALSE
12	GTEx	Testis	FAM65C	0.25	-0.01	enet	52	0.00	3.1e-01	-1.134	-5.2	1.7e-07	0.26	0.05	0.26	FALSE
2	CommonMind	Brain Pre-frontal Cortex	DDX27	0.04	0.04	enet	11	0.07	7.3e-09	-4.530	5.2	2.1e-07	0.04	0.30	0.69	FALSE
4	GTEx	Brain Cerebellar Hemisphere	RP11-112L6.4	0.37	0.12	enet	32	0.08	3.7e-03	1.975	5.2	2.2e-07	-0.29	0.09	0.18	FALSE