[Hub]/) : Traits : Blood Red Count :

chr20:46,840,115-50,071,258

Best TWAS P=2.37e-35 · Best GWAS P=8.68e-61 conditioned to 4.19e-18

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CSE1L 0.08 0.07 bslmm 503 0.05 1.7e-06 -4.654 -5.5 3.1e-08 -0.10 0.53 0.47 FALSE
2 CommonMind Brain Pre-frontal Cortex DDX27 0.04 0.04 enet 11 0.07 7.3e-09 -4.530 5.2 2.1e-07 0.04 0.30 0.69 FALSE
3 GTEx Adipose Subcutaneous UBE2V1 0.11 0.05 enet 19 0.06 8.6e-06 2.307 -6.3 2.8e-10 0.14 0.24 0.06 FALSE
4 GTEx Brain Cerebellar Hemisphere RP11-112L6.4 0.37 0.12 enet 32 0.08 3.7e-03 1.975 5.2 2.2e-07 -0.29 0.09 0.18 FALSE
5 GTEx Brain Frontal Cortex BA9 RP11-112L6.4 0.29 0.25 lasso 5 0.22 1.8e-06 1.975 5.5 3.1e-08 -0.20 0.43 0.05 FALSE
6 GTEx Cells Transformed fibroblasts PTPN1 0.11 0.00 lasso 4 0.00 4.5e-01 -6.984 -7.0 3.5e-12 0.16 0.05 0.05 TRUE
7 GTEx Colon Sigmoid ARFGEF2 0.15 0.12 lasso 1 0.07 2.3e-03 5.987 -6.0 2.1e-09 -0.10 0.01 0.93 TRUE
8 GTEx Colon Transverse FAM65C 0.16 0.06 lasso 3 0.04 5.7e-03 12.048 -12.4 2.4e-35 0.40 0.28 0.06 TRUE
9 GTEx Nerve Tibial CSE1L 0.12 0.01 lasso 10 0.03 5.7e-03 -4.237 -5.9 3.0e-09 -0.09 0.19 0.24 FALSE
10 GTEx Nerve Tibial PTPN1 0.11 0.01 lasso 3 0.01 5.4e-02 0.097 6.4 2.0e-10 -0.28 0.10 0.24 TRUE
11 GTEx Nerve Tibial TMEM189 0.18 0.00 enet 36 0.05 3.1e-04 -1.592 10.2 2.9e-24 -0.35 0.08 0.52 TRUE
12 GTEx Testis FAM65C 0.25 -0.01 enet 52 0.00 3.1e-01 -1.134 -5.2 1.7e-07 0.26 0.05 0.26 FALSE
13 GTEx Testis RP4-530I15.9 0.36 0.42 lasso 1 0.42 3.3e-20 11.697 11.7 1.3e-31 -0.51 1.00 0.00 FALSE
14 METSIM Adipose PARD6B 0.03 0.00 bslmm 494 0.01 5.1e-02 6.375 -9.6 9.9e-22 0.40 0.04 0.37 TRUE
15 YFS Blood ZNFX1 0.06 0.05 lasso 3 0.05 1.4e-16 5.769 -5.8 5.8e-09 -0.07 0.01 0.99 FALSE