[Hub]/) : Traits : Systolic Blood Pressure : ← →

chr1:88,453,303-90,145,331

Best TWAS P=1.3e-19 · Best GWAS P=2.21e-21 conditioned to 0.000901

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	CCBL2	0.58	0.68	lasso	7	0.69	1.4e-117	5.1	-6.1	1.2e-09	-0.64	1.00	0.00	FALSE
2	GTEx	Adipose Subcutaneous	CCBL2	0.26	0.21	enet	15	0.23	1.2e-18	5.1	-5.7	9.6e-09	-0.61	1.00	0.00	FALSE
3	GTEx	Adipose Visceral Omentum	PKN2	0.09	0.04	enet	8	0.05	1.2e-03	8.4	7.6	3.0e-14	0.67	0.30	0.39	FALSE
4	GTEx	Adipose Visceral Omentum	CCBL2	0.21	0.10	enet	7	0.15	5.2e-08	5.0	-5.8	5.0e-09	-0.65	0.84	0.14	FALSE
5	GTEx	Artery Aorta	CCBL2	0.29	0.20	enet	24	0.24	1.5e-13	5.0	-5.3	1.5e-07	-0.58	0.99	0.01	FALSE
6	GTEx	Artery Coronary	CCBL2	0.29	0.19	enet	5	0.14	1.6e-05	5.4	-5.3	1.0e-07	-0.60	0.75	0.05	FALSE
7	GTEx	Artery Tibial	CCBL2	0.30	0.24	lasso	8	0.29	4.9e-23	5.1	-6.1	1.1e-09	-0.66	1.00	0.00	FALSE
8	GTEx	Brain Cerebellar Hemisphere	CCBL2	0.31	0.18	lasso	5	0.23	1.7e-06	8.4	-8.4	3.1e-17	-0.85	0.05	0.94	FALSE
9	GTEx	Brain Cortex	CCBL2	0.59	0.39	enet	13	0.37	3.0e-11	8.4	-6.3	2.2e-10	-0.67	0.90	0.10	FALSE
10	GTEx	Brain Frontal Cortex BA9	CCBL2	0.47	0.38	enet	25	0.48	1.5e-14	5.0	-6.1	1.1e-09	-0.64	0.86	0.14	FALSE
11	GTEx	Brain Hippocampus	CCBL2	0.39	0.27	lasso	5	0.13	5.1e-04	5.1	5.3	1.3e-07	0.53	0.21	0.29	FALSE
12	GTEx	Brain Hypothalamus	CCBL2	0.34	0.00	enet	34	0.13	6.4e-04	5.1	-5.3	9.9e-08	-0.43	0.21	0.28	FALSE
13	GTEx	Brain Nucleus accumbens basal ganglia	CCBL2	0.38	0.44	enet	20	0.32	2.1e-09	5.5	-6.1	1.1e-09	-0.68	0.77	0.23	FALSE
14	GTEx	Cells Transformed fibroblasts	CCBL2	0.65	0.61	enet	32	0.67	6.1e-67	5.1	-5.7	1.5e-08	-0.62	1.00	0.00	FALSE
15	GTEx	Colon Sigmoid	CCBL2	0.22	0.12	enet	4	0.09	5.2e-04	5.1	-5.2	1.5e-07	-0.56	0.32	0.40	FALSE
16	GTEx	Colon Transverse	CCBL2	0.30	0.19	lasso	8	0.26	1.2e-12	5.1	-6.9	5.0e-12	-0.69	0.98	0.02	FALSE
17	GTEx	Esophagus Muscularis	CCBL2	0.25	0.29	enet	18	0.28	1.6e-17	5.1	-6.3	2.9e-10	-0.65	1.00	0.00	FALSE
18	GTEx	Heart Atrial Appendage	CCBL2	0.30	0.20	enet	11	0.15	3.4e-07	5.1	-5.6	1.9e-08	-0.60	0.98	0.01	FALSE
19	GTEx	Muscle Skeletal	CCBL2	0.12	0.15	enet	9	0.16	5.4e-15	5.1	-5.2	2.0e-07	-0.58	1.00	0.00	FALSE
20	GTEx	Nerve Tibial	CCBL2	0.42	0.33	enet	38	0.38	3.4e-28	5.1	-5.4	8.0e-08	-0.58	1.00	0.00	FALSE
21	GTEx	Pancreas	CCBL2	0.26	0.21	lasso	4	0.23	5.3e-10	8.4	-7.3	2.8e-13	-0.70	0.17	0.81	FALSE
22	GTEx	Pancreas	RBMXL1	0.27	0.16	enet	36	0.16	1.8e-07	-5.2	-5.4	7.6e-08	-0.41	0.93	0.02	FALSE
23	GTEx	Pituitary	CCBL2	0.45	0.30	lasso	2	0.26	2.7e-07	8.4	-7.4	1.5e-13	-0.72	0.20	0.78	FALSE
24	GTEx	Stomach	CCBL2	0.16	0.08	lasso	4	0.15	9.0e-08	5.1	-6.5	7.8e-11	-0.72	0.55	0.40	FALSE
25	GTEx	Testis	CCBL2	0.47	0.56	lasso	5	0.57	1.2e-30	5.1	-5.1	2.9e-07	-0.57	1.00	0.00	FALSE
26	GTEx	Thyroid	CCBL2	0.22	0.15	enet	22	0.22	9.8e-17	8.4	-7.0	2.2e-12	-0.68	0.94	0.06	FALSE
27	GTEx	Thyroid	RBMXL1	0.09	0.02	enet	19	0.04	2.7e-04	2.2	-5.5	3.8e-08	-0.60	0.04	0.88	FALSE
28	METSIM	Adipose	CCBL2	0.27	0.14	lasso	6	0.18	6.4e-27	5.1	-7.2	7.9e-13	-0.71	1.00	0.00	FALSE
29	ROSMAP	Brain Pre-frontal Cortex	CCBL2	0.43	0.56	enet	31	0.56	1.1e-87	5.1	-6.2	5.4e-10	-0.66	1.00	0.00	FALSE
30	YFS	Blood	GTF2B	0.01	0.00	lasso	3	0.01	2.3e-04	9.5	9.1	1.3e-19	0.86	0.01	0.98	TRUE
31	The Cancer Genome Atlas	Breast Invasive Carcinoma	PKN2	0.02	0.01	enet	5	0.01	2.3e-03	6.8	7.0	2.6e-12	0.82	0.02	0.79	FALSE
32	The Cancer Genome Atlas	Glioblastoma Multiforme	CCBL2	0.36	0.32	enet	37	0.33	6.4e-11	5.0	-7.2	4.3e-13	-0.69	0.02	0.98	FALSE
33	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	GTF2B	0.04	0.01	blup	53	0.01	2.2e-02	-4.6	6.8	1.3e-11	0.50	0.08	0.13	FALSE
34	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	CCBL2	0.28	0.42	enet	15	0.40	1.5e-24	5.1	-5.4	6.5e-08	-0.59	1.00	0.00	FALSE
35	The Cancer Genome Atlas	Brain Lower Grade Glioma	CCBL2	0.28	0.32	enet	24	0.31	2.5e-35	5.1	-5.9	3.3e-09	-0.61	1.00	0.00	FALSE
36	The Cancer Genome Atlas	Brain Lower Grade Glioma	PKN2	0.05	0.01	enet	8	0.02	1.6e-03	7.2	6.3	2.4e-10	0.75	0.11	0.82	FALSE
37	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	CCBL2	0.10	0.07	enet	12	0.08	2.0e-09	5.5	-5.5	3.6e-08	-0.53	0.98	0.01	FALSE
38	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	CCBL2	0.15	0.18	lasso	2	0.16	3.5e-07	5.4	-5.4	7.5e-08	-0.61	0.76	0.18	FALSE
39	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	CCBL2	0.37	0.47	enet	19	0.46	3.1e-20	5.5	-5.2	1.5e-07	-0.61	1.00	0.00	FALSE
40	The Cancer Genome Atlas	Prostate Adenocarcinoma	CCBL2	0.20	0.34	lasso	2	0.35	9.5e-38	5.5	-5.3	1.1e-07	-0.58	1.00	0.00	FALSE
41	The Cancer Genome Atlas	Rectum Adenocarcinoma	CCBL2	0.35	0.27	lasso	6	0.25	1.7e-06	5.5	-5.5	3.9e-08	-0.60	0.10	0.87	FALSE
42	The Cancer Genome Atlas	Skin Cutaneous Melanoma	GBP3	0.35	0.13	blup	43	0.12	4.2e-04	2.2	-5.5	5.1e-08	-0.43	0.06	0.26	FALSE