TWAS hub - RBMXL1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0640	0.0330	7.1e-03	0.005	0.006	0.012	0.010	0.029	7.8e-02	0.0590	1.3e-02	0.0180	1.7e-04
2	GTEx	Adipose Subcutaneous	0.0970	0.0430	1.9e-03	0.025	NA	-0.001	NA	0.017	3.8e-03	NA	4.0e-01	NA	1.4e-02
3	GTEx	Artery Tibial	0.0584	0.0297	6.1e-03	0.056	NA	0.048	NA	0.048	3.5e-05	NA	1.1e-04	NA	1.2e-04
4	GTEx	Esophagus Mucosa	0.1600	0.0460	2.4e-07	0.133	NA	0.145	NA	0.163	3.7e-09	NA	6.3e-10	NA	5.1e-11
5	GTEx	Pancreas	0.2750	0.0710	4.9e-06	0.159	NA	0.165	NA	0.148	3.1e-07	NA	1.8e-07	NA	8.6e-07
6	GTEx	Skin Not Sun Exposed Suprapubic	0.1820	0.0620	4.4e-04	0.003	NA	-0.005	NA	0.004	2.2e-01	NA	7.5e-01	NA	1.9e-01
7	GTEx	Skin Sun Exposed Lower leg	0.0910	0.0370	5.1e-04	0.063	NA	0.072	NA	0.076	6.3e-06	NA	1.5e-06	NA	6.9e-07
8	GTEx	Spleen	0.3370	0.0990	1.2e-03	-0.011	NA	-0.011	NA	-0.010	8.8e-01	NA	8.1e-01	NA	7.3e-01
9	GTEx	Thyroid	0.0870	0.0360	2.3e-04	0.017	NA	0.044	NA	0.028	1.8e-02	NA	2.7e-04	NA	3.2e-03
10	ROSMAP	Brain Pre-frontal Cortex	0.0469	0.0206	7.5e-04	0.052	0.018	0.039	0.022	0.041	2.6e-07	0.0017	8.7e-06	0.0006	4.4e-06
11	TCGA	Lung Adenocarcinoma	0.0345	0.0190	9.7e-04	0.010	0.021	0.014	NA	0.013	2.3e-02	0.0013	8.5e-03	NA	9.9e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Hearing aid user	5.3	6.0	10.6	-1.8	-2.0	-3.2	-2.2	-3.2	-2.9	-2.5	-2.6	-2.3	-2.6	0.1
Mother’s age at death	4.2	5.2	9.5	2.5	3.1	2.6	2.5	0.9	0.9	3.0	2.2	1.7	3.0	-1.1
Commuting to job workplace: Walk	3.5	3.8	7.0	1.5	2.3	2.2	1.4	1.6	2.5	1.9	1.4	2.5	2.7	-0.3
Birth weight of first child	3.2	5.8	21.1	1.9	2.5	3.0	1.7	1.5	1.9	2.0	2.2	4.6	2.2	-1.3
Wears glasses or contact lenses	3.2	3.7	7.6	-2.1	-1.6	-2.7	-2.6	0.2	-1.4	-2.8	-0.9	-1.7	-2.2	-1.3
Height	3.1	59.9	193.2	6.9	7.8	9.8	6.8	4.7	4.9	8.0	4.9	13.9	9.1	0.2
Rheumatoid Arthritis	3.0	4.1	9.1	-1.6	-2.1	-2.7	-2.0	-0.5	-1.8	-2.2	-1.1	-3.0	-2.7	-0.4
Medication: Metformin	3.0	4.2	7.8	-2.2	-1.8	-2.6	-2.8	-1.1	-1.5	-2.8	-1.7	-1.8	-2.5	-0.3
Medication: Blood pressure	3.0	5.8	14.1	-2.6	-2.2	-2.5	-0.8	-3.7	-0.4	-1.4	-2.5	-3.8	-2.9	0.5
Heel bone mineral density (BMD) T-score, automated (left)	2.9	6.6	19.4	-1.4	-2.3	-3.4	-2.4	-2.2	-2.5	-2.7	-1.8	-4.4	-2.5	0.6
Noisy workplace	2.8	3.5	9.6	-2.4	-1.6	-2.2	-2.5	-0.1	-0.7	-2.1	-1.0	-3.1	-1.8	-0.4
Standing height	2.8	27.8	93.3	4.3	5.3	6.5	4.4	4.0	3.6	5.0	4.0	9.7	5.9	-0.7
Commuting to job workplace: Car/motor vehicle	2.8	3.2	9.4	0.3	-1.9	-2.2	-0.8	-1.9	-2.2	-1.6	-1.4	-3.1	-1.7	0.9
Medication: Aspirin	2.7	3.5	7.2	-1.4	-1.5	-2.6	-2.1	-1.4	-1.6	-2.1	-1.9	-2.7	-1.8	-0.3
Medication: Aspirin	2.7	3.5	7.2	-1.5	-1.7	-2.5	-2.1	-1.2	-1.4	-2.1	-2.1	-2.7	-1.9	0.0
Hair/balding pattern: Pattern 2	2.6	3.3	6.3	1.9	2.2	2.3	1.5	1.7	0.6	1.9	1.4	2.5	2.4	-0.3
Hayfever/allergic rhinitis (self-reported)	2.6	3.4	8.2	-2.9	-2.1	-1.6	-1.7	-1.7	-0.1	-1.7	-2.2	-1.6	-2.1	1.5
Number of self-reported non-cancer illnesses	2.6	4.5	10.3	-2.0	-1.9	-2.4	-1.9	-3.2	-0.7	-1.9	-3.2	-1.9	-2.2	0.6
Illnesses of father: Heart disease	2.4	3.4	9.9	-0.1	-3.2	-1.6	-0.3	-1.4	-0.8	-1.5	-1.2	-2.6	-1.7	2.9
Loneliness, isolation	2.4	3.3	10.0	3.2	1.5	2.1	1.3	1.7	-0.3	1.7	1.5	2.1	2.2	-0.7
Medication: Bendroflumethiazide	2.4	3.6	6.5	-2.4	-2.3	-1.9	-0.6	-2.5	0.4	-1.0	-1.7	-2.5	-2.1	1.7
Irritability	2.4	4.1	11.6	-1.2	-1.8	-2.5	-2.2	-0.7	-1.8	-2.5	-1.6	-3.4	-2.3	-0.2
Ever depressed for a whole week	2.4	3.0	5.4	2.0	2.2	1.8	0.7	1.9	0.2	1.5	1.7	1.9	2.3	-1.6
Heel bone mineral density (BMD) T-score, automated (right)	2.3	5.3	15.9	-1.6	-2.1	-2.9	-2.2	-1.9	-1.9	-2.5	-2.1	-4.0	-2.1	0.8
Comparative height size at age 10	2.3	12.7	31.2	3.7	3.6	4.4	3.4	2.4	1.9	3.7	3.0	5.6	4.3	-0.3
Sitting height	2.2	15.6	53.4	3.0	3.8	4.5	3.1	3.9	2.5	3.3	3.8	7.3	4.3	-0.7
Supplements: Calcium	2.2	2.5	9.5	2.1	0.6	1.6	1.1	0.2	0.4	1.4	0.3	3.1	1.9	1.8
Ever had prostate specific antigen (PSA) test	2.1	2.4	4.8	1.7	1.7	1.4	0.7	1.9	0.3	1.3	2.2	1.6	2.1	-0.9
Alcohol drinker status: Previous	2.1	2.4	4.2	-1.9	-2.0	-1.6	-1.6	-1.0	-0.0	-1.9	-2.0	-1.0	-1.6	1.1
Alzheimer’s Disease (including proxy)	2.0	2.9	7.8	1.5	1.5	2.1	1.9	0.9	1.5	1.8	1.4	2.8	1.8	0.0
Systolic Blood Pressure	2.0	9.8	30.2	-1.6	-3.0	-2.3	0.2	-5.4	0.2	-0.5	-3.9	-5.5	-2.6	3.0
Eye problems/disorders: Diabetes related eye disease	2.0	2.2	4.3	-1.5	-1.9	-1.5	-1.9	-0.5	-1.3	-2.0	-1.3	-0.7	-2.1	0.3
Diabetes (father)	1.9	2.4	7.3	0.0	-1.6	-1.6	-1.7	-0.8	-2.7	-1.8	-1.1	-1.8	-1.5	0.5
Had menopause	1.9	2.4	11.3	0.4	1.1	-0.9	-2.1	1.2	-2.0	-1.6	0.2	-0.4	-0.7	-3.4
Suffer from ‘nerves’	1.9	2.9	8.1	0.6	0.8	2.0	2.3	1.6	2.8	2.1	2.1	1.1	1.0	0.0
Medication: Gliclazide	1.9	2.2	4.4	-1.4	-0.9	-2.0	-1.7	-0.6	-1.3	-1.7	-0.7	-2.1	-1.8	-1.4
Medication: Lisinopril	1.9	2.4	4.0	-1.8	-1.9	-1.9	-1.8	-0.9	-0.8	-2.0	-1.4	-1.5	-1.8	0.7
Vascular/heart problems diagnosed by doctor	1.9	5.3	21.3	2.0	1.4	2.4	0.5	4.6	-0.4	0.8	3.1	3.2	2.1	-0.5
Medication: Atenolol	1.8	2.3	5.7	-1.7	-1.3	-2.0	-1.2	-1.6	-0.5	-1.1	-0.2	-2.4	-2.1	-0.9
Number of incorrect matches in round	1.8	3.0	8.3	-2.2	-1.1	-1.9	-1.9	-0.2	-0.6	-2.2	-1.6	-2.9	-1.7	-0.6
Ever unenthusiastic/disinterested for a whole week	1.8	2.3	4.4	1.3	1.5	1.7	1.2	1.4	1.3	1.5	1.5	1.9	2.1	-0.4
Prospective memory result	1.8	2.2	10.2	-0.2	-0.9	-0.8	1.4	-3.2	1.1	0.0	-1.3	-1.0	-0.1	2.7
Number of full sisters	1.8	2.2	3.9	-1.5	-1.9	-1.9	-1.6	0.6	-1.2	-1.9	-0.8	-1.6	-2.0	0.2
Ever had stillbirth, spontaneous miscarriage or termination	1.8	1.9	3.2	-1.4	-1.0	-1.4	-1.7	-1.3	-1.5	-1.6	-1.5	-0.9	-1.8	-0.8
HbA1C	1.7	1.9	4.8	1.0	0.1	1.8	1.7	1.0	2.2	1.5	0.7	1.0	1.1	1.9
Hearing difficulty/problems: Yes	1.6	2.5	5.9	-0.0	-1.9	-1.7	-1.8	0.1	-2.3	-1.7	-1.0	-2.4	-1.2	0.8
Systolic blood pressure, automated reading	1.6	4.5	20.0	-0.8	-2.0	-2.1	-0.5	-2.6	-0.9	-0.9	-2.4	-4.5	-2.2	1.3
Pulse wave reflection index	1.6	1.9	4.3	-1.4	-1.8	-1.8	-1.1	-1.1	-0.5	-1.3	-0.5	-2.1	-1.8	0.8
Ever highly irritable/argumentative for 2 days	1.6	1.9	6.2	-1.4	-1.3	-1.5	-1.1	0.1	-0.7	-1.4	-0.7	-2.5	-2.0	-0.9
Bipolar Disorder (2011)	1.5	1.5	6.9	0.7	1.0	0.8	0.6	2.6	0.6	1.1	1.7	0.1	1.4	-0.4
Average weekly fortified wine intake	1.5	1.8	10.4	-1.8	1.0	-1.0	-1.1	0.0	-0.4	-1.1	-0.1	0.3	-1.0	-3.2
High blood pressure	1.5	4.3	22.2	-1.5	-1.1	-1.7	0.2	-4.7	0.9	-0.2	-2.9	-2.5	-1.6	0.7
Hayfever, allergic rhinitis or eczema	1.5	3.3	6.0	-2.5	-2.4	-1.8	-1.5	-1.4	-0.3	-2.1	-1.6	-2.1	-2.4	0.8
Mouth/teeth dental problems: Loose teeth	1.5	1.8	4.3	-0.6	-1.7	-1.5	-1.4	-0.2	-1.9	-2.0	-0.7	-0.5	-2.1	-0.5
Hypertension (Self-reported)	1.5	4.1	19.1	-1.7	-1.2	-1.8	0.0	-4.4	0.7	-0.3	-2.8	-2.6	-1.7	0.5
Schizophrenia vs Biploar Disorder	1.4	1.9	4.0	-0.9	-1.5	-1.3	-0.2	-2.0	-0.9	-1.0	-1.8	-1.7	-1.7	1.2
Diverticular disease/diverticulitis (self-reported)	1.4	1.7	3.6	-1.8	-0.3	-1.2	-1.8	-0.0	-0.7	-1.7	-0.3	-0.8	-1.7	-1.9
High blood pressure (mother)	1.4	1.9	13.7	0.1	-0.5	-1.1	0.1	-3.7	-0.9	-0.2	-1.8	-1.3	-0.5	0.4
Medication: Ramipril	1.4	1.8	4.8	-1.4	-1.3	-1.5	-0.7	-2.0	-0.5	-0.9	-0.9	-2.2	-1.5	0.4
Time employed in main current job	1.4	1.7	3.2	-1.8	-1.2	-1.4	-0.5	-1.8	0.4	-1.2	-1.7	-0.7	-1.8	0.4
Breastfed as a baby	1.4	1.7	5.8	-1.6	0.3	-0.4	-1.1	2.1	-0.4	-0.3	1.3	-0.9	-1.2	-2.4
Birth weight	1.4	3.1	9.2	2.3	1.7	2.3	1.2	0.6	-0.4	2.0	1.3	3.0	1.9	-0.6
Number of children fathered	1.4	1.6	5.0	-1.0	-1.4	-1.3	-0.4	-0.7	-0.8	-1.1	-1.5	-2.2	-1.0	1.3
Alcohol drinker status: Never	1.4	1.6	4.9	-0.7	-0.2	-1.4	-2.2	-0.4	-2.1	-1.3	-1.6	-1.2	-0.7	0.0
Bipolar Disorder (2018)	1.3	2.0	7.7	1.1	1.6	0.9	0.2	2.8	0.2	0.6	1.9	0.5	1.3	-1.9
Allergy or Eczema	1.3	3.3	6.8	-2.6	-2.1	-1.8	-1.5	-1.7	-0.4	-1.8	-1.5	-2.5	-2.2	0.5
Hearing difficulty/problems with background noise	1.3	2.0	4.5	-0.6	-1.3	-1.1	-1.7	1.6	-2.1	-1.7	-0.3	-1.7	-1.4	-1.0
Age at last live birth	1.3	1.9	5.2	1.8	1.3	1.7	1.0	0.7	0.2	1.4	0.9	2.3	1.9	-0.0
Alzheimer’s Disease (in father)	1.2	1.3	3.5	1.7	1.1	1.1	0.7	1.2	-0.4	0.6	1.1	1.9	1.2	-0.3
Waist Hip Ratio (WHR)	1.2	5.5	10.4	2.3	2.6	3.2	1.8	3.0	1.4	1.7	2.0	3.2	2.5	-1.2
Leg fat-free mass (left)	1.2	6.2	14.5	2.6	2.4	2.9	2.3	1.3	1.3	2.7	2.1	3.8	3.3	1.0
Frequency of unenthusiasm / disinterest in last 2 weeks	1.2	1.6	5.7	2.4	1.3	1.2	0.5	1.6	-0.1	0.8	1.0	1.2	1.5	-0.8
Pulse rate	1.2	2.0	4.7	1.4	0.3	1.8	2.2	-0.0	1.1	1.8	0.6	1.4	1.5	1.6
Heart disease (mother)	1.2	1.4	3.8	-1.4	0.1	-1.7	-1.4	-0.6	-0.4	-1.1	-0.2	-1.7	-0.8	-1.9
Forced expiratory volume in 1-second (FEV1), predicted	1.2	2.5	10.3	0.3	0.3	1.8	1.5	-0.1	2.2	1.4	0.3	3.2	1.7	1.4
Illnesses of father: None of the above (group 1)	1.2	1.5	5.3	-0.6	1.8	0.4	-0.2	1.5	-0.0	0.7	1.7	0.9	0.7	-2.3
Intelligence (Savage-Jansen 2018)	1.1	3.3	14.1	0.7	2.2	2.0	0.7	2.1	1.1	1.2	0.8	3.8	1.9	-1.1
Diabetes (mother)	1.1	1.5	5.3	2.3	1.6	1.0	0.7	1.1	-0.9	0.6	1.1	0.5	1.2	-1.2
Leg predicted mass (left)	1.1	6.0	14.5	2.5	2.4	2.9	2.2	1.2	1.3	2.6	2.0	3.8	3.3	1.0
Trunk fat-free mass	1.1	6.4	15.0	2.8	2.7	3.0	2.5	1.3	1.2	2.8	1.8	3.9	3.3	0.4
Loud music exposure frequency	1.1	1.2	4.6	0.4	-0.3	-1.0	-1.8	1.0	-2.1	-1.4	-0.2	-0.7	-0.3	-0.9
Medication: Ventolin 100micrograms inhaler	1.1	1.3	3.6	1.2	-0.5	1.3	1.6	-1.2	0.6	1.2	-1.1	1.0	0.3	1.9
Whole body fat-free mass	1.1	6.4	15.4	2.9	2.6	3.0	2.3	1.4	1.1	2.7	1.9	3.9	3.4	0.6
Leg fat-free mass (right)	1.1	5.7	14.1	2.8	2.2	2.7	2.0	1.6	0.9	2.4	2.1	3.8	3.2	1.0
Leg predicted mass (right)	1.1	6.0	15.0	2.8	2.3	2.8	2.0	1.6	0.9	2.5	2.2	3.9	3.3	0.9
Forced vital capacity (FVC)	1.0	4.0	10.1	1.3	1.2	2.6	2.4	0.8	2.2	2.0	1.3	3.2	2.2	1.4
Trunk predicted mass	1.0	6.0	13.9	2.8	2.6	2.9	2.4	1.2	1.1	2.7	1.7	3.7	3.2	0.4
Headache pain in last month	1.0	1.7	4.4	0.5	1.4	1.7	1.1	0.3	2.1	1.1	0.6	1.9	1.3	-1.0
Shortness of breath walking on level ground	1.0	1.1	3.1	-1.8	-0.7	-0.7	-1.2	0.9	0.1	-1.0	0.8	-0.3	-1.4	-1.6
Qualifications: College or University degree	1.0	3.3	14.4	0.8	1.2	2.1	1.6	1.1	1.1	1.9	1.8	3.8	1.8	0.1
Migraine (self-reported)	1.0	1.2	3.2	-0.9	-1.8	-0.8	-0.9	0.1	-0.4	-1.4	-1.2	-0.9	-1.1	1.6
Mouth/teeth dental problems: Mouth ulcers	1.0	1.5	5.1	2.1	0.3	1.3	2.3	1.0	0.2	1.3	1.1	0.7	0.8	0.6
Breast cancer (self-reported)	1.0	1.2	5.7	0.8	0.8	-0.3	-1.2	0.5	-2.4	-0.8	0.2	0.7	-0.1	-1.8
Osteoarthritis (self-reported)	1.0	1.3	3.8	0.3	1.1	-0.3	-0.7	1.6	-1.5	-0.6	1.6	-0.8	0.1	-1.9
Whole body water mass	1.0	5.9	14.0	2.7	2.6	2.8	2.2	1.4	1.1	2.5	1.9	3.7	3.2	0.5
Ulcerative Colitis (UC)	0.9	1.7	12.5	-0.0	-1.8	0.2	1.4	-0.1	0.5	0.4	-0.3	-0.3	-0.2	3.5
Cardiovascular Disease	0.9	3.1	13.0	-1.7	-0.9	-0.9	1.4	-3.6	1.9	0.8	-2.0	-1.9	-1.2	1.0
Maternal smoking around birth	0.9	1.3	3.8	-0.9	-1.9	-1.2	-0.9	-0.0	-0.8	-0.9	-0.7	-1.5	-1.0	1.6
Stomach or abdominal pain in last month	0.9	1.2	4.9	-0.3	0.9	0.6	-0.3	2.2	0.7	0.1	1.4	0.5	0.3	-2.0
Chronic bronchitis/emphysema (father)	0.9	1.1	2.4	0.9	0.5	1.0	1.4	-0.6	1.1	1.0	-0.1	1.1	1.3	1.5
Diabetes (self-reported)	0.9	1.4	3.8	-0.6	-0.8	-1.3	-1.9	0.8	-1.2	-1.9	-0.6	-1.0	-1.2	-0.7
Fluid intelligence score	0.9	1.8	6.5	-0.3	1.4	1.4	0.8	1.7	1.3	1.1	0.9	2.6	1.4	-0.4
Leg fat percentage (right)	0.9	3.2	11.4	-1.5	-1.1	-2.1	-1.7	-1.9	-1.6	-1.4	-0.9	-3.4	-1.8	-0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.9	1.1	4.8	1.7	-0.1	0.5	0.3	2.2	-0.9	0.4	1.6	-0.2	0.8	0.4
Medication: Seretide 50 evohaler	0.9	1.1	2.4	1.6	0.9	1.5	1.1	0.1	0.2	1.5	-0.0	1.3	1.0	0.1
Had major operations	0.9	1.1	2.4	1.5	1.6	0.7	0.1	0.9	0.0	0.6	1.0	1.0	1.5	-1.1
Mineral and other dietary supplements	0.9	1.1	4.9	-1.1	-1.2	-0.9	-1.2	-0.4	0.2	-0.9	-0.9	-2.2	-0.5	0.9
Medication: Atorvastatin	0.9	1.1	7.3	0.3	-1.2	0.2	0.9	-0.3	1.2	0.2	-0.9	-0.5	0.4	2.7
Illnesses of father: High blood pressure	0.9	1.1	3.2	0.7	-0.8	-0.3	-0.1	-1.2	-0.8	-0.4	-1.7	-1.8	-0.3	1.7
Basal metabolic rate	0.9	5.2	12.2	2.5	2.3	2.7	2.1	1.2	1.0	2.4	1.8	3.5	3.0	0.6
Leg fat percentage (left)	0.9	3.2	11.3	-1.3	-1.2	-2.2	-1.8	-1.6	-1.8	-1.6	-0.8	-3.4	-1.8	-0.4
Age at First Birth	0.8	1.2	6.0	-0.1	1.3	1.0	0.3	0.7	1.0	0.5	0.7	2.4	1.0	-1.1
LDL Cholesterol	0.8	1.3	2.2	0.9	1.3	1.5	1.3	0.8	0.8	1.2	1.2	1.5	1.2	0.4
Angina	0.8	1.1	2.1	0.1	-0.5	-1.1	-1.2	-1.3	-1.5	-1.1	-1.3	-1.4	-0.7	0.2
Financial difficulties in last 2 years	0.8	1.1	5.6	2.4	-0.3	0.5	0.3	0.4	-1.2	0.5	-0.0	0.5	0.9	1.8
Allergy	0.8	1.9	3.4	1.8	1.8	1.4	1.2	0.8	0.4	1.8	1.5	1.1	1.8	-0.7
Pain all over the body in last month	0.8	0.9	3.6	0.7	-0.7	-0.5	-0.4	-1.9	-1.4	-0.5	-0.9	-0.1	-0.1	1.1
Forced expiratory volume in 1-second (FEV1)	0.8	2.8	5.9	0.8	0.5	1.9	2.4	-0.2	2.2	1.8	1.1	2.0	1.7	2.2
Illnesses of mother	0.8	1.0	6.4	-0.2	-0.2	1.0	0.2	2.5	0.9	-0.0	0.7	1.3	0.4	1.0
Peak expiratory flow (PEF)	0.8	1.9	4.9	0.6	0.2	1.4	1.9	0.4	1.5	1.5	1.6	1.2	1.3	2.2
Forced vital capacity (FVC), Best measure	0.8	2.8	9.1	0.8	1.1	2.2	1.8	0.3	1.8	1.6	0.6	3.0	2.1	1.2
Neck or shoulder pain in last month	0.8	1.1	4.1	0.3	0.5	1.1	0.9	1.4	1.2	1.3	2.0	0.1	0.3	-0.7
Angina (self-reported)	0.8	1.0	2.2	0.2	-0.5	-1.0	-1.2	-1.2	-1.4	-1.2	-1.2	-1.5	-0.5	0.4
Alcohol intake frequency.	0.8	1.8	4.5	-0.4	-0.6	-1.6	-2.1	-0.9	-1.7	-1.7	-2.0	-0.9	-0.9	-0.5
Qualifications: NVQ or HND or HNC or equivalent	0.8	0.9	4.2	1.1	-0.9	-0.6	-0.4	0.1	-2.1	-0.6	0.2	-1.1	-0.7	1.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	1.0	4.0	1.0	0.2	0.8	1.4	0.6	0.1	1.2	2.0	0.7	0.6	0.8
Commuting to job workplace: Cycle	0.8	1.0	2.2	1.3	0.1	1.2	0.6	1.5	0.1	0.9	1.3	1.2	1.1	0.8
Basal cell carcinoma (self-reported)	0.8	1.0	5.0	-1.0	0.7	0.3	0.3	1.1	0.9	0.0	0.9	1.2	-0.2	-2.2
Depressed Affect (Nagel 2018)	0.7	1.5	2.9	1.7	1.1	1.3	1.3	1.4	0.6	1.3	1.4	0.5	1.5	-0.6
Prostate Cancer	0.7	1.0	3.1	1.8	0.5	1.0	1.0	1.4	-0.3	0.9	1.3	0.5	0.6	0.2
Heel T-Score	0.7	5.4	31.4	-1.2	-2.6	-2.5	-0.7	-2.2	-0.4	-1.3	-0.9	-5.6	-1.8	1.7
Supplements: Glucosamine	0.7	1.0	4.1	1.0	1.6	0.6	0.5	0.8	-0.2	0.3	0.9	0.8	0.6	-2.0
Alcohol intake versus 10 years previously	0.7	1.0	2.4	-0.6	-0.4	-1.5	-1.3	-0.8	-0.9	-0.9	-0.9	-1.5	-0.9	-0.3
Number of live births	0.7	1.0	2.6	0.6	0.3	-0.5	-1.3	1.4	-1.3	-0.7	0.7	-1.0	-0.4	-1.6
Medication: Lansoprazole	0.7	0.8	2.4	-1.6	0.1	-0.9	-0.9	-1.6	0.2	-0.6	-0.8	-0.7	-0.6	-0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.1	6.2	2.5	0.0	0.7	0.7	0.8	-1.0	0.8	0.8	0.6	1.1	0.6
Age at first live birth	0.7	1.2	5.2	1.2	0.8	1.1	0.7	-0.2	0.8	0.6	-0.2	2.3	1.6	0.2
Pulse wave peak to peak time	0.7	0.8	1.4	1.1	0.9	1.2	1.0	0.6	1.1	0.9	0.3	0.5	1.2	0.2
Emphysema/chronic bronchitis	0.7	0.7	2.5	0.9	1.6	0.8	0.3	0.7	-0.2	0.3	-0.1	0.8	1.3	-1.2
Chest pain or discomfort	0.7	1.0	3.9	0.4	0.3	-0.6	-1.1	0.4	-1.6	-1.0	-0.2	-0.5	-0.8	-2.0
Medication for cholesterol	0.7	1.0	2.6	1.5	0.5	1.0	0.6	1.6	0.1	0.2	0.8	1.6	1.3	0.4
Arm fat-free mass (left)	0.7	3.7	7.2	2.3	2.1	2.2	1.7	1.3	0.7	2.0	1.7	2.7	2.6	0.1
Irritable Bowel Disease (IBD)	0.6	1.5	9.3	-0.0	-1.4	0.1	1.5	0.6	0.9	0.6	0.5	-0.8	0.1	3.0
Number of treatments/medications taken	0.6	1.0	4.7	-1.6	-0.8	-0.5	-0.3	-2.2	0.9	-0.1	-0.8	-0.5	-0.8	0.5
Medication: Co-codamol	0.6	0.7	2.1	-0.3	-0.6	-1.1	-1.0	-0.9	-1.4	-1.0	-0.6	-0.1	-0.8	0.1
Townsend deprivation index at recruitment	0.6	0.8	2.2	-0.2	-1.2	-1.0	-1.0	0.5	-1.5	-1.3	-0.6	-0.3	-0.9	0.1
Tinnitus: Yes, but not now, but have in the past	0.6	0.7	1.6	0.3	-1.3	-0.7	-0.6	-0.5	-1.1	-0.6	-0.9	-1.0	-0.7	0.9
Nervous feelings	0.6	1.0	4.6	-0.8	-1.5	-0.9	-0.1	-0.6	0.8	-0.6	-0.4	-2.1	-1.0	0.9
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	2.0	4.1	0.4	0.3	1.5	1.7	-0.6	1.9	1.4	0.2	1.8	1.7	2.0
Arm fat-free mass (right)	0.6	3.1	8.5	1.9	2.0	2.0	1.3	0.8	0.7	1.8	1.4	2.9	2.4	0.1
Number of full brothers	0.6	0.7	3.4	0.1	1.1	0.3	-0.3	1.8	0.2	0.2	0.8	0.3	0.4	-1.5
Worry too long after embarrassment	0.6	1.0	2.6	-0.6	-0.7	-1.0	-0.7	-0.2	-0.9	-1.3	-0.6	-1.2	-1.6	-1.4
Wheeze or whistling in the chest in last year	0.6	1.1	3.5	1.9	0.1	1.1	0.5	1.1	-0.8	0.7	0.7	1.6	1.1	0.9
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	1.5	0.7	1.2	1.1	0.6	0.2	-0.0	1.2	0.5	1.1	1.0	-0.7
Medication: Allopurinol	0.6	0.9	3.6	0.3	1.7	0.1	-0.3	0.8	0.2	0.2	0.8	0.9	0.7	-1.9
Medication: Omeprazole	0.6	0.7	1.8	1.1	0.2	0.7	1.2	1.1	0.3	0.8	1.4	0.2	0.7	0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.7	2.0	-1.1	-1.4	-0.6	0.6	-0.4	0.2	-0.3	0.7	-1.2	-1.0	0.9
Arm predicted mass (right)	0.6	3.0	7.7	1.9	1.9	1.9	1.4	1.0	0.9	1.7	1.3	2.8	2.5	0.3
Leg pain on walking	0.6	0.7	4.3	-0.9	1.1	-0.3	-0.3	0.4	0.9	-0.2	0.2	0.5	0.1	-2.1
Osteoporosis (self-reported)	0.6	0.8	2.3	-0.0	-0.0	0.9	0.8	-0.9	1.4	0.9	-0.5	1.5	0.1	1.1
Smoking status: Current	0.6	0.9	5.1	1.1	-0.7	0.0	0.1	-0.9	0.1	0.1	-1.4	-0.4	0.9	2.3
Average weekly champagne plus white wine intake	0.6	0.8	2.3	-0.7	1.1	0.6	0.7	0.0	1.2	0.7	0.9	1.0	0.4	-1.5
Commuting to job workplace: Public transport	0.6	0.8	4.2	-2.0	-0.6	0.2	-0.1	0.1	1.7	-0.0	-0.1	0.7	-0.3	0.3
Supplements: Fish oil (including cod liver oil)	0.6	0.8	1.9	1.4	1.1	0.7	0.7	0.4	-0.9	0.8	0.7	1.3	0.6	-0.5
Medication: Paracetamol	0.6	0.9	3.0	-0.7	-1.0	-0.7	-0.7	-1.7	0.2	-0.7	-1.2	-1.2	-0.7	0.7
Average weekly beer plus cider intake	0.6	0.9	5.0	0.4	-1.0	-0.1	0.9	-1.2	0.1	0.0	-1.1	-0.3	0.1	2.2
Diastolic blood pressure, automated reading	0.6	1.7	6.6	0.0	-1.1	-0.8	0.3	-2.6	-0.2	0.0	-1.8	-1.9	-1.0	1.6
Arm predicted mass (left)	0.6	2.8	5.3	2.0	1.8	1.9	1.4	1.3	0.5	1.7	1.6	2.3	2.3	0.3
Depression (Nagel 2018)	0.5	0.8	3.5	1.9	1.0	0.8	0.6	0.7	-0.3	0.6	0.8	0.5	1.0	-0.8
Breast Cancer	0.5	1.1	6.1	-1.2	-1.1	-0.8	-0.0	-0.8	0.1	-0.3	0.2	-2.5	-1.6	0.0
Ovarian Cancer	0.5	0.7	3.5	0.3	1.5	0.5	0.1	0.0	0.2	0.5	0.2	0.9	0.6	-1.9
Body Mass Index (BMI) (2010)	0.5	0.7	2.4	-1.6	-0.2	-0.5	-0.5	0.6	0.1	-0.9	0.8	-0.9	-0.7	-1.2
Neuroticism (2016)	0.5	0.8	5.1	0.9	-0.5	-0.7	-0.4	0.5	-0.7	-0.6	0.4	-2.2	-0.5	-0.6
Type 2 Diabetes (T2D) (2012)	0.5	0.5	2.5	-0.7	-0.7	-0.5	0.1	-0.7	-0.0	-0.2	-0.9	-1.6	-0.7	0.5
Ulcerative Colitis	0.5	0.7	4.8	0.7	-0.9	0.3	0.9	0.2	-0.3	0.2	-0.3	0.2	0.2	2.2
Sensitivity / hurt feelings	0.5	0.9	4.0	0.4	0.8	0.6	0.1	2.0	0.4	0.4	1.0	0.2	0.8	-1.6
Frequency of depressed mood in last 2 weeks	0.5	0.7	2.8	1.7	0.7	0.7	0.4	0.8	0.2	0.6	1.4	0.1	0.8	-0.8
Supplements: Zinc	0.5	0.5	1.4	0.6	1.1	0.8	0.6	0.2	0.2	0.8	-0.3	1.1	1.2	-0.1
Severe depression (siblings)	0.5	0.6	3.9	0.2	-0.1	0.7	0.8	2.0	0.7	0.7	0.5	-0.1	0.1	0.1
Current tobacco smoking	0.5	0.8	3.8	1.4	-0.5	0.0	-0.1	-0.3	-0.4	0.0	-1.1	-0.5	0.9	1.9
Age when periods started (menarche)	0.5	1.1	1.9	0.5	1.4	1.1	1.4	-0.9	1.3	1.3	-0.0	1.2	1.2	-0.1
Serious illness, injury or assault to yourself	0.5	0.6	2.4	-1.6	-1.1	-0.4	-0.0	0.3	0.3	-0.3	0.8	1.0	-1.0	0.3
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	1.8	0.8	-0.0	-0.6	-1.3	1.2	-1.4	-0.7	0.1	-1.4	-0.2	-0.8
Had other major operations	0.5	0.6	2.2	-1.5	-0.2	-0.7	-0.7	1.3	0.5	-0.7	0.8	-0.5	-0.4	-0.5
Mouth/teeth dental problems	0.5	0.8	2.6	-1.6	-0.6	-0.7	-0.9	-1.1	0.8	-0.4	-1.1	0.0	-0.2	1.2
Illnesses of siblings	0.5	0.7	2.8	1.1	0.5	0.9	0.3	1.1	-0.4	0.2	0.8	1.7	0.9	0.2
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	1.8	1.3	0.9	1.1	0.6	0.3	0.4	1.1	0.8	1.0	1.1	-0.2
Asthma	0.5	0.9	3.5	1.9	-0.4	0.7	0.6	-0.2	-0.6	0.3	-1.0	0.9	0.8	1.6
Pulse wave Arterial Stiffness index	0.5	0.6	1.3	-0.9	-0.9	-1.0	-0.8	-0.6	-1.1	-0.8	-0.4	-0.0	-1.1	-0.1
Tense / ‘highly strung’	0.5	0.8	3.2	0.7	0.4	0.7	1.3	-1.8	1.0	1.2	-0.7	-0.3	0.3	0.4
Gout (self-reported)	0.5	0.7	2.4	0.9	1.6	0.2	-0.2	0.6	-0.4	0.0	0.9	1.1	0.7	-1.4
Medication: Blood pressure	0.5	0.9	4.7	-0.2	-0.1	-0.1	0.9	-2.2	1.4	1.0	-0.3	-0.9	0.1	0.8
Medication: Ibuprofen	0.5	0.6	2.8	-0.1	1.4	0.4	0.0	-0.0	0.8	0.4	-0.2	0.6	0.5	-1.7
Smoking status: Previous	0.5	0.7	2.8	-0.7	0.2	-0.6	-0.8	1.0	-0.5	-0.8	1.1	-0.3	-0.7	-1.7
Ever had bowel cancer screening	0.5	0.6	1.5	-0.6	-1.0	-0.9	-0.9	-0.2	-0.7	-1.2	0.2	-0.2	-1.2	-0.5
Diabetes diagnosed by doctor	0.5	0.8	2.0	-0.6	-0.3	-1.0	-1.4	0.7	-0.8	-1.4	-0.5	-1.0	-0.7	-0.8
Asthma (self-reported)	0.5	1.0	3.7	1.9	-0.0	1.0	0.8	-0.0	-0.3	0.6	-0.6	1.2	1.2	1.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.2	2.6	0.7	0.6	1.3	1.6	-0.3	1.2	1.4	1.0	0.9	1.1	1.0
Miserableness	0.5	0.9	2.1	1.4	0.4	0.9	1.0	1.4	0.2	0.9	1.1	0.6	0.9	0.1
Tinnitus: Yes, now most or all of the time	0.5	0.6	3.4	-0.2	0.9	0.4	-0.3	1.0	0.6	0.2	0.7	-0.4	0.3	-1.9
Pain type(s) experienced in last month: Hip pain	0.5	0.6	1.8	-0.1	-0.3	-1.3	-1.1	0.1	-0.9	-1.3	0.3	-1.0	-0.3	-0.6
Alzheimer’s Disease (in mother)	0.4	0.5	2.0	0.1	0.8	0.8	0.4	0.1	0.9	0.7	0.5	1.4	0.6	-0.3
Crohns Disease (2017)	0.4	0.9	2.4	-0.8	-1.2	-0.6	0.3	1.2	0.7	-0.0	1.1	-1.6	-0.3	1.3
Verbal and Numeric Reasoning (VNR)	0.4	1.0	3.4	0.2	1.8	0.7	-0.3	0.9	0.2	0.4	0.1	1.8	1.2	-1.4
Fasting Glucose	0.4	0.5	1.6	-1.2	0.2	-0.3	-0.3	0.8	1.2	-0.7	-0.1	-0.8	-0.1	-0.5
Type 2 Diabetes (T2D) (2018)	0.4	0.8	1.5	-0.9	-0.2	-1.0	-1.1	0.2	-0.8	-1.0	-0.9	-1.2	-0.8	-0.9
Chronotype (morning person)	0.4	0.8	3.9	0.2	-0.1	0.5	0.8	2.0	1.1	0.4	1.5	-0.8	0.3	0.3
Hand grip strength (left)	0.4	1.0	3.4	1.0	0.4	1.1	1.0	0.3	0.8	0.9	-0.3	1.8	1.1	0.9
Vitamin and mineral supplements	0.4	0.5	2.0	-1.4	-0.3	-0.5	-0.2	0.2	0.9	-0.5	-0.4	-1.3	-0.5	-0.1
Qualifications: CSEs or equivalent	0.4	0.5	1.8	-0.0	0.2	0.7	1.3	-0.7	1.2	1.1	0.6	-0.0	0.1	0.0
Waist circumference	0.4	1.5	3.4	1.8	1.5	1.4	0.9	0.6	-0.3	1.2	1.1	1.5	1.6	-0.0
Past tobacco smoking	0.4	0.7	2.0	1.4	0.6	1.1	1.0	-0.3	0.2	1.0	-0.3	0.6	1.1	1.0
Heart attack	0.4	0.5	2.5	-0.4	0.6	-0.3	-0.6	0.5	-0.4	-0.4	0.2	-0.9	-0.3	-1.6
Medication: Simvastatin	0.4	0.6	2.7	0.5	0.7	-0.8	-0.5	-0.4	-1.6	-0.1	-0.3	-0.0	-0.1	-1.2
Weight	0.4	1.7	4.3	1.6	1.4	1.5	1.0	0.7	-0.0	1.4	1.2	2.1	1.7	0.3
Happiness	0.4	0.5	1.0	0.7	0.5	0.9	1.0	0.8	0.2	1.0	0.2	0.8	0.2	-0.6
Mouth/teeth dental problems: Dentures	0.4	0.8	2.8	0.3	0.1	-0.4	-0.9	0.5	-1.7	-0.6	-0.1	-1.1	-0.6	-1.6
Qualifications: O levels/GCSEs or equivalent	0.4	0.7	3.6	0.1	-1.1	-0.6	-0.4	-0.8	-0.1	-0.4	-0.9	-0.4	-0.2	1.9
Blood clot in the leg (DVT)	0.4	0.5	1.3	-1.2	-0.1	-0.9	-0.8	-0.3	0.1	-0.8	-0.9	0.0	-0.7	-0.7
Medication for cholesterol, blood pressure or diabetes	0.4	0.6	3.3	0.1	-0.2	0.1	-0.7	1.8	-0.9	-0.9	0.8	0.4	-0.3	-0.4
Chronic bronchitis/emphysema (mother)	0.4	0.5	1.6	-0.7	-0.7	-0.4	-0.0	-0.9	0.5	-0.1	-1.2	-1.3	-0.5	0.0
Family relationship satisfaction	0.4	0.5	2.0	0.1	1.1	0.5	0.0	-0.3	0.3	0.4	-0.3	1.1	0.4	-1.4
Illness, injury, bereavement, stress in last 2 years	0.4	0.4	1.6	-0.9	0.2	-0.5	-0.9	-0.1	0.0	-0.9	-0.5	-0.6	-0.2	-1.3
Supplements: Vitamin C	0.4	0.5	1.5	0.4	0.7	0.1	-0.8	1.2	-1.0	0.0	0.6	0.1	0.3	-0.8
Knee pain experienced in last month	0.4	0.6	2.0	1.3	0.7	0.0	0.4	0.7	-0.9	0.5	1.4	-0.0	0.7	-0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	1.6	-0.4	-1.1	-0.9	-0.5	-0.3	-0.2	-0.7	-0.0	-0.8	-1.3	0.5
Eye problems/disorders: Cataract	0.4	0.5	2.3	-0.9	0.4	-0.1	-0.5	-0.8	0.2	-0.3	-0.5	1.5	-0.1	-1.0
Ever taken oral contraceptive pill	0.4	0.4	1.9	0.7	-0.3	-0.4	-1.0	0.4	-1.4	-0.7	-0.2	0.4	-0.1	-0.5
Eye problems/disorders: Glaucoma	0.4	0.4	1.3	0.0	-0.4	-0.6	-0.1	-1.1	-0.5	-0.4	-0.9	-1.0	-0.8	-0.7
Heart attack/myocardial infarction (self-reported)	0.4	0.6	2.8	-0.4	0.6	-0.5	-0.8	0.3	-0.6	-0.6	0.0	-1.1	-0.3	-1.7
Pack years of smoking	0.4	0.6	1.6	-0.5	-0.2	-0.9	-1.2	0.3	-0.9	-1.3	-0.4	-0.4	-0.8	-0.9
Bipolar Disorder or Schizophrenia	0.3	0.7	4.7	-0.2	0.8	0.5	0.1	2.2	0.8	0.2	0.8	0.3	0.3	-0.9
Major Depression (MDD)	0.3	0.3	1.4	0.5	-0.6	0.0	0.1	1.2	-0.5	0.2	0.7	-0.2	-0.1	1.0
Coronary Artery Disease (CAD)	0.3	0.4	2.3	-0.6	0.0	-0.2	-0.1	-0.4	-0.2	0.5	-0.8	-1.5	-0.4	0.0
Crohns Disease (2012)	0.3	0.4	1.0	-0.2	-0.5	0.4	0.3	0.9	0.8	0.6	0.7	-0.8	0.2	1.0
HDL Cholesterol	0.3	0.6	1.1	0.9	0.8	0.9	0.6	0.2	0.4	1.0	0.7	1.0	0.6	-0.8
Primary Biliary Cirrhosis	0.3	0.4	1.1	-1.0	-0.0	0.4	0.2	-0.6	0.6	0.3	-0.7	1.1	-0.0	0.4
Respiratory disease	0.3	0.6	2.2	0.6	-0.7	0.1	0.1	-1.3	-0.8	-0.2	-1.5	0.9	0.1	1.0
Hand grip strength (right)	0.3	0.7	3.1	0.7	-0.3	0.8	0.0	0.9	0.3	0.4	-0.2	1.8	0.9	1.2
Fed-up feelings	0.3	0.6	2.4	1.5	0.7	0.9	0.6	0.1	-0.4	1.1	0.3	0.5	1.0	-0.3
Relative age voice broke	0.3	0.4	2.4	-0.5	-0.4	-0.3	-0.9	1.5	-0.3	-0.7	0.4	0.2	-0.3	-0.3
Taking other prescription medications	0.3	0.4	1.5	-0.2	-0.8	-0.2	-0.0	-1.2	0.6	-0.4	-0.5	-0.1	-0.4	1.1
Body mass index (BMI)	0.3	1.5	5.7	-0.4	-0.9	-1.6	-1.0	-1.1	-1.5	-0.9	-0.6	-2.4	-0.9	0.7
Qualifications: None of the above	0.3	0.7	3.5	-0.6	0.4	0.4	1.2	0.1	1.9	0.8	0.0	-1.1	0.5	0.2
Father’s age at death	0.3	0.4	2.4	1.6	0.4	0.5	0.0	0.3	-0.2	0.3	-0.7	0.6	0.5	-0.1
Hair/balding pattern: Pattern 3	0.3	0.5	1.9	-0.6	-0.8	-0.7	-0.5	-0.5	0.0	-0.9	-0.7	-0.3	-0.4	1.4
Depression (self-reported)	0.3	0.4	2.2	1.0	-0.5	0.3	0.4	0.4	0.1	0.2	-0.1	0.3	0.3	1.5
Length of working week for main job	0.3	0.3	1.6	-0.4	0.0	0.3	0.4	-0.8	1.2	0.3	0.6	0.6	0.3	0.3
Exposure to tobacco smoke at home	0.3	0.3	1.9	0.5	-0.4	0.4	-0.3	1.4	-0.0	-0.2	0.3	0.7	-0.1	-0.2
Hair/balding pattern: Pattern 4	0.3	0.8	3.0	0.1	-0.2	-0.5	-0.2	-0.3	-1.6	-0.1	0.1	-1.7	-0.8	-1.4
Exposure to tobacco smoke outside home	0.3	0.4	1.3	-0.5	-0.2	-0.1	0.1	1.1	0.7	-0.4	0.6	0.1	-0.9	-1.2
Health satisfaction	0.3	0.4	1.9	-1.2	-0.4	-0.2	-0.2	0.0	1.4	-0.4	0.1	-0.7	-0.5	-0.6
Illnesses of siblings: Diabetes	0.3	0.4	1.2	-0.6	0.3	0.4	0.5	-0.5	0.8	0.6	-0.7	-1.1	-0.0	0.4
Arm fat percentage (left)	0.3	1.1	3.3	-0.9	-0.7	-1.4	-1.0	-1.3	-0.9	-0.9	-0.4	-1.8	-0.9	0.1
Average weekly red wine intake	0.3	0.5	1.6	0.2	-0.2	0.6	0.9	0.5	1.2	0.4	0.3	0.7	0.3	1.3
Friendships satisfaction	0.3	0.4	1.3	-1.0	-0.2	-0.6	-0.1	-0.5	-0.3	-0.4	-0.4	-0.5	-1.0	-1.1
Ever smoked	0.3	0.6	1.7	-0.7	-0.5	-1.1	-1.3	-0.1	-0.3	-1.1	-0.4	-0.4	-0.9	-0.7
Age started oral contraceptive pill	0.3	0.3	1.5	-0.5	0.8	0.0	-0.7	0.2	0.4	-0.1	-0.5	0.7	0.3	-1.2
Medication: Omeprazole (e.g. Zanprol)	0.3	0.3	1.6	0.6	-0.1	0.3	0.4	1.3	0.0	0.3	0.9	0.2	0.2	0.4
Heart disease (siblings)	0.3	0.4	1.8	-0.5	0.2	-0.1	0.2	0.3	1.2	0.2	0.6	-1.4	-0.1	-0.6
Schizophrenia (2018)	0.2	0.3	1.3	-1.1	-0.3	-0.1	0.0	0.6	0.8	-0.3	-0.5	-0.1	-0.7	0.3
Worry (Nagel 2018)	0.2	0.5	2.5	-0.4	0.3	-0.0	0.7	-0.9	1.6	0.6	-0.1	-1.0	0.0	-0.2
Reaction Time	0.2	0.3	1.2	-0.7	-0.6	-0.2	0.5	-0.1	1.1	-0.1	-0.3	-0.4	-0.5	0.6
Mean Putamen Volume	0.2	0.2	0.9	-0.0	-0.3	0.0	-0.9	-0.4	-0.8	0.2	-0.1	0.5	-0.5	-0.3
Lupus	0.2	0.3	1.3	1.1	0.0	0.1	0.1	-0.5	-1.0	-0.1	0.2	0.7	0.3	-0.2
Triglycerides	0.2	0.4	1.5	0.6	1.2	0.6	0.3	0.6	0.3	0.4	0.3	0.2	0.9	-0.5
Blood Eosinophil Count	0.2	1.6	5.3	0.0	-0.4	-1.2	-1.7	0.0	-2.2	-1.4	-0.7	-2.3	-0.2	-0.1
Blood Red Count	0.2	1.9	17.9	0.2	0.2	-0.2	0.7	0.4	1.0	0.8	0.5	-4.2	-0.1	0.2
Smoking Status	0.2	0.4	1.7	0.3	-0.4	-0.5	-0.4	-0.7	-0.0	-0.4	-0.6	-0.7	0.3	1.3
Hypothyroidism (self reported)	0.2	0.4	0.9	0.1	-0.9	-0.8	-0.5	-0.8	-0.6	-0.3	-0.1	-0.9	-0.6	0.9
Lung FVC	0.2	0.9	3.4	-0.1	-0.9	-0.7	-0.2	-1.8	-0.6	-0.7	-1.4	-1.0	-0.6	0.7
Average weekly spirits intake	0.2	0.2	0.7	0.2	0.4	0.0	0.1	0.2	-0.6	0.3	0.2	-0.8	-0.1	-0.8
Relative age of first facial hair	0.2	0.5	1.1	0.5	0.9	0.3	-0.3	1.1	-0.1	0.3	1.0	0.8	1.0	-0.6
Other serious medical condition/disability diagnosed by doctor	0.2	0.3	1.0	-0.5	0.5	0.6	0.3	0.1	1.0	0.6	-0.1	0.4	0.2	-0.7
Ever had hysterectomy (womb removed)	0.2	0.2	0.9	-0.8	-0.4	0.1	0.4	0.6	1.0	0.1	0.4	0.4	-0.5	0.1
Medication for hormone replacement therapy	0.2	0.3	0.7	-0.1	-0.7	-0.2	-0.6	-0.1	-0.6	-0.5	-0.5	-0.8	-0.4	0.5
Pack years adult smoking proportion	0.2	0.3	0.8	-0.1	0.0	-0.5	-0.8	0.2	-0.5	-0.9	-0.5	-0.0	-0.4	-0.7
Multivitamins +/- minerals	0.2	0.3	1.7	0.4	-0.2	0.0	0.1	-1.3	-0.0	0.1	-0.5	0.7	0.0	0.4
Impedance of arm (right)	0.2	0.9	3.1	-0.2	0.4	1.2	1.0	0.7	1.8	0.8	0.5	1.6	0.2	-0.1
Arm fat percentage (right)	0.2	0.9	3.4	-0.8	-0.7	-1.3	-0.7	-1.3	-0.6	-0.7	-0.3	-1.8	-1.0	0.2
Hip circumference	0.2	1.0	2.0	1.4	1.0	0.9	0.8	0.2	-0.4	1.2	1.4	1.1	1.2	0.4
Worrier / anxious feelings	0.2	0.4	2.3	-0.2	-0.4	-0.3	0.4	-1.5	0.6	0.3	-0.4	-1.0	-0.6	0.2
Falls in the last year	0.2	0.3	1.6	1.0	0.2	-0.3	-0.5	-0.4	-1.3	-0.2	-0.2	-0.3	0.2	0.1
Qualifications: A levels/AS levels or equivalent	0.2	0.5	1.7	-0.3	-1.1	-0.4	-0.3	-0.2	-0.7	-0.5	-1.2	0.1	-0.4	1.3
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.3	1.2	0.6	0.3	-0.4	0.2	-0.8	-0.3	0.1	0.1	-1.1	-0.2	-0.6
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	1.1	0.1	0.7	0.3	0.4	-0.2	1.0	0.3	-0.2	0.5	0.2	-0.8
Medication: Cholesterol lowering	0.2	0.2	0.8	0.9	0.6	0.2	0.6	-0.3	-0.5	0.6	-0.2	0.0	0.4	-0.1
Impedance of arm (left)	0.2	0.7	3.2	-0.7	0.5	0.8	0.3	0.7	1.6	0.3	0.3	1.8	0.2	-0.5
Mouth/teeth dental problems: Bleeding gums	0.2	0.2	0.7	-0.3	-0.3	-0.4	-0.2	0.3	-0.1	-0.5	0.2	-0.8	-0.9	-0.6
Medication: Paracetamol	0.2	0.4	1.6	0.4	-0.3	0.3	0.4	-0.9	0.9	0.2	-0.4	-0.1	0.4	1.3
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	0.7	-0.6	-0.8	-0.8	-0.8	-0.8	0.0	-0.4	-0.2	-0.8	-0.7	0.6
Medication: Amlodipine	0.2	0.3	1.1	-0.5	0.2	-0.0	0.7	-0.3	0.4	0.1	0.5	-0.1	-0.6	-1.1
High blood pressure (siblings)	0.2	0.3	1.3	0.8	0.7	0.2	0.2	-1.1	-0.1	0.6	0.0	-0.2	0.2	-0.8
Body fat percentage	0.2	0.9	2.2	-1.0	-0.6	-1.3	-1.1	-1.0	-0.7	-0.8	-0.2	-1.5	-1.0	-0.2
Comparative body size at age 10	0.2	0.5	1.7	0.6	0.3	0.4	0.6	-1.3	0.8	0.4	-0.3	1.1	0.7	0.8
Medication for pain relief, constipation, heartburn	0.2	0.3	0.8	0.4	0.7	0.4	0.1	0.5	-0.6	0.2	0.5	0.9	0.4	-0.9
Mood swings	0.2	0.4	1.5	0.3	-0.2	0.4	1.0	-0.4	1.2	0.6	0.0	-0.9	-0.2	0.2
Long-standing illness, disability or infirmity	0.2	0.3	1.4	-0.9	0.0	0.4	-0.3	1.2	0.4	-0.0	0.2	-0.1	-0.0	-0.5
Qualifications: nursing, teaching	0.2	0.3	1.3	-0.0	0.6	-0.2	-0.5	0.1	-0.7	-0.2	0.1	0.9	0.3	-1.2
Back pain experienced in last month	0.2	0.4	1.8	-0.2	0.0	-0.4	-1.3	-0.5	-0.4	-0.7	-0.3	0.3	-0.4	-0.9
Guilty feelings	0.2	0.3	1.5	0.5	-0.4	-0.3	-0.4	0.9	-0.4	-0.2	0.2	-1.2	-0.3	-0.2
High cholesterol (Self-reported)	0.2	0.4	1.2	0.5	1.0	0.5	0.9	-0.2	0.5	1.1	0.0	0.1	0.8	-0.3
Risk taking	0.2	0.4	1.3	-0.0	-0.5	-0.2	-0.6	1.1	-0.7	-0.4	-0.7	-0.7	-0.5	0.4
Fractured/broken bones in last 5 years	0.2	0.3	1.6	-0.4	0.3	0.3	0.5	0.2	1.3	0.3	0.3	0.7	0.3	-0.1
Unable to work because of sickness or disability	0.2	0.3	1.9	-0.3	-0.2	-0.5	-0.3	0.8	-0.2	-0.2	0.6	-1.4	0.0	0.1
Myopia	0.2	0.3	1.2	0.9	0.5	0.3	0.1	1.1	-0.2	0.1	0.8	0.3	0.7	-0.0
Cholesterol lowering medication	0.2	0.3	1.4	-0.0	-0.6	-0.8	-0.1	-1.2	-0.0	-0.1	-0.7	-0.1	-0.4	0.6
Pain experienced in last month	0.2	0.3	2.0	0.4	-0.7	-0.3	0.2	-0.2	-0.5	-0.1	-0.6	-0.2	-0.1	1.4
Deep venous thrombosis (DVT) (self-reported)	0.2	0.3	1.0	-1.0	0.2	-0.5	-0.5	-0.0	0.2	-0.5	-0.5	0.6	-0.4	-0.9
Neuroticism (Nagel 2018)	0.1	0.3	1.4	0.4	0.1	-0.1	0.4	0.6	0.6	0.2	0.6	-1.2	0.3	-0.4
Schizophrenia (2014)	0.1	0.3	1.3	-1.1	-0.2	-0.2	-0.2	0.4	0.5	-0.4	-1.0	-0.5	-0.7	-0.0
Blood Platelet Count	0.1	0.8	4.5	-0.6	-0.7	-0.7	0.0	-1.3	0.5	0.1	-0.5	-2.1	-0.6	0.9
Blood White Count	0.1	1.1	3.5	1.5	0.1	0.4	1.0	-0.8	-0.3	1.4	-0.2	-1.4	0.8	1.9
BMI	0.1	0.4	2.3	-0.5	-0.3	-0.8	-0.2	0.1	-0.7	-0.2	0.5	-1.5	-0.3	0.0
Lung FEV1/FVC ratio	0.1	0.7	3.0	-0.2	-0.3	-0.7	0.7	-1.7	0.5	0.2	-0.3	-1.3	0.3	1.3
Neuroticism	0.1	0.3	2.3	-0.1	-0.1	-0.5	-0.1	-0.4	0.4	-0.1	-0.1	-1.5	-0.1	-0.6
Tanning	0.1	1.8	3.2	-0.2	-1.3	-1.7	-1.0	-1.7	-1.8	-1.6	-1.0	-1.6	-1.4	0.5
Ever used hormone-replacement therapy (HRT)	0.1	0.1	0.2	0.3	0.4	0.3	0.2	0.4	0.3	0.2	0.3	0.0	0.3	-0.4
Impedance of leg (right)	0.1	0.6	1.9	-1.4	-0.1	0.0	-0.1	-0.4	1.3	-0.2	-0.7	-0.5	-0.9	-1.1
Trunk fat percentage	0.1	0.2	0.5	-0.7	-0.2	-0.6	-0.6	-0.6	-0.2	-0.3	0.2	-0.4	-0.6	-0.3
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.3	-0.4	-0.2	-0.1	0.4	0.5	0.6	0.1	0.3	-0.1	-0.6	-0.2
Medication: Levothyroxine sodium	0.1	0.2	1.3	0.5	-0.0	-0.2	-0.3	0.2	-0.0	0.1	1.1	-0.3	0.3	0.2
Impedance of leg (left)	0.1	0.7	2.0	-1.4	-0.5	-0.5	-0.6	-0.1	0.7	-0.7	-0.7	-0.8	-1.3	-1.2
Alcohol usually taken with meals	0.1	0.1	0.2	-0.4	-0.4	-0.2	-0.0	0.3	0.3	-0.1	0.4	-0.1	-0.2	0.4
Neuroticism score	0.1	0.3	1.4	0.7	0.2	-0.1	0.0	0.2	-0.1	0.2	0.2	-1.2	-0.2	-1.1
Lung cancer (father)	0.1	0.1	0.7	-0.2	0.1	-0.0	-0.1	-0.4	-0.1	0.3	-0.1	0.1	0.3	0.9
Glaucoma (self-reported)	0.1	0.1	0.4	0.3	0.0	0.1	0.5	-0.6	0.1	0.2	-0.5	-0.0	-0.0	-0.2
Eye problems/disorders: None of the above	0.1	0.2	0.7	0.2	0.1	0.0	-0.1	-0.3	-0.1	-0.1	-0.6	-0.7	0.3	0.8
Mean time to correctly identify matches	0.1	0.1	0.4	-0.1	0.1	0.1	0.2	0.6	0.6	0.0	0.1	0.2	-0.2	-0.5
Leg fat mass (right)	0.1	0.3	1.1	-0.4	-0.1	-0.6	-0.4	-1.0	-0.6	-0.1	-0.1	-1.0	-0.3	-0.1
Overall health rating	0.1	0.2	1.1	0.1	-0.1	0.3	-0.1	-1.1	-0.2	0.2	-0.4	0.7	-0.3	0.1
Handedness (chirality/laterality): Left-handed	0.1	0.1	0.2	0.3	0.2	0.3	0.5	-0.3	0.3	0.2	0.1	0.5	0.1	-0.4
Financial situation satisfaction	0.1	0.1	0.5	0.6	0.0	0.1	-0.3	0.3	-0.5	-0.3	-0.3	0.1	-0.0	-0.7
Number of operations (self-reported)	0.1	0.2	0.6	-0.7	-0.3	-0.4	-0.5	0.7	-0.1	-0.4	-0.3	-0.2	-0.2	-0.4
Impedance of whole body	0.1	0.4	1.8	-0.9	0.0	0.3	0.0	0.4	1.4	-0.0	-0.0	0.9	-0.4	-0.6
Leg fat mass (left)	0.1	0.3	0.9	-0.3	-0.1	-0.6	-0.5	-0.9	-0.7	-0.2	-0.1	-1.0	-0.3	0.0
Hair Pigment	0.0	1.2	5.6	-0.4	-0.3	-1.1	-0.6	0.8	-0.6	-0.9	0.7	-2.4	-1.2	-1.4
Trunk fat mass	0.0	0.2	0.5	0.2	0.6	0.3	0.1	-0.1	0.1	0.5	0.7	0.7	0.4	-0.1
Arm fat mass (right)	0.0	0.2	0.6	-0.3	-0.3	-0.6	-0.2	-0.7	-0.2	-0.2	0.0	-0.8	-0.2	0.5
Whole body fat mass	0.0	0.0	0.2	0.0	0.2	-0.1	-0.2	-0.3	-0.4	0.1	0.4	0.1	0.0	-0.0
Pulse rate, automated reading	0.0	0.1	0.2	0.3	0.0	0.4	0.3	0.0	-0.3	0.4	-0.3	0.0	0.2	0.3
Arm fat mass (left)	0.0	0.1	0.4	-0.2	-0.0	-0.5	-0.3	-0.5	-0.5	-0.2	0.1	-0.6	-0.1	0.3

Hub : Genes

RBMXL1

Models

Trait associations