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chr20:56,858,751-58,262,841

Best TWAS P=5.33e-23 · Best GWAS P=2.76e-42 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	NELFCD	0.43	0.31	enet	36	0.38	3.3e-33	-5.5	6.3	3.9e-10	0.16	1.00	0.00	FALSE
2	GTEx	Adipose Visceral Omentum	NELFCD	0.29	0.20	lasso	3	0.23	2.8e-12	-5.4	5.6	2.5e-08	0.14	1.00	0.00	FALSE
3	GTEx	Artery Aorta	NELFCD	0.43	0.34	lasso	4	0.37	1.8e-21	-5.5	5.8	5.8e-09	0.20	1.00	0.00	TRUE
4	GTEx	Artery Coronary	NELFCD	0.36	0.20	lasso	7	0.22	6.5e-08	-5.4	5.8	8.4e-09	0.13	0.85	0.02	FALSE
5	GTEx	Artery Tibial	NELFCD	0.24	0.16	lasso	4	0.16	1.2e-12	-5.5	6.0	2.6e-09	0.24	1.00	0.00	FALSE
6	GTEx	Breast Mammary Tissue	NELFCD	0.40	0.20	lasso	7	0.19	4.1e-10	-5.5	5.6	1.8e-08	0.18	1.00	0.00	FALSE
7	GTEx	Breast Mammary Tissue (Male)	NELFCD	0.05	-0.01	lasso	1	-0.01	7.8e-01	-5.5	5.5	4.1e-08	0.18	0.05	0.06	FALSE
8	GTEx	Breast Mammary Tissue (Female)	NELFCD	0.35	0.16	lasso	7	0.09	1.1e-03	-5.5	5.8	8.8e-09	0.17	0.18	0.06	FALSE
9	GTEx	Esophagus Gastroesophageal Junction	NELFCD	0.45	0.14	lasso	9	0.18	3.4e-07	-5.5	5.6	1.9e-08	0.18	0.96	0.01	FALSE
10	GTEx	Esophagus Mucosa	NELFCD	0.32	0.20	enet	8	0.27	2.1e-18	-5.4	6.6	4.8e-11	0.21	1.00	0.00	FALSE
11	GTEx	Esophagus Muscularis	NELFCD	0.23	0.15	enet	14	0.18	6.7e-11	-5.5	5.7	9.5e-09	0.18	1.00	0.00	FALSE
12	GTEx	Heart Atrial Appendage	NELFCD	0.23	0.17	enet	23	0.19	4.5e-09	-6.9	5.4	7.6e-08	0.11	0.85	0.01	FALSE
13	GTEx	Lung	NELFCD	0.22	0.22	lasso	2	0.21	5.0e-16	-5.5	5.6	2.1e-08	0.18	1.00	0.00	FALSE
14	GTEx	Nerve Tibial	NELFCD	0.30	0.17	enet	25	0.23	2.8e-16	-5.5	7.3	2.8e-13	0.26	1.00	0.00	FALSE
15	GTEx	Pancreas	NELFCD	0.17	0.03	lasso	3	0.07	5.7e-04	-5.5	5.4	5.6e-08	0.16	0.47	0.02	FALSE
16	GTEx	Skin Not Sun Exposed Suprapubic	NELFCD	0.22	0.15	lasso	3	0.11	1.9e-06	-5.5	5.5	4.0e-08	0.17	0.98	0.00	FALSE
17	GTEx	Skin Sun Exposed Lower leg	NELFCD	0.28	0.21	lasso	7	0.22	1.1e-17	-5.5	6.0	1.8e-09	0.17	1.00	0.00	FALSE
18	GTEx	Spleen	NELFCD	0.51	0.31	lasso	7	0.18	2.9e-05	-5.5	5.3	1.0e-07	0.16	0.54	0.03	FALSE
19	METSIM	Adipose	NELFCD	0.25	0.21	bslmm	540	0.23	1.0e-33	-5.5	5.3	1.3e-07	0.10	1.00	0.00	TRUE
20	The Cancer Genome Atlas	Colon Adenocarcinoma	TH1L	0.08	0.05	lasso	3	0.07	8.1e-05	-5.4	6.5	9.6e-11	0.12	0.01	0.98	TRUE
21	The Cancer Genome Atlas	Esophageal Carcinoma	TH1L	0.19	0.16	blup	46	0.19	8.9e-07	-6.9	6.2	5.8e-10	0.06	0.00	0.99	FALSE
22	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	TH1L	0.10	0.06	blup	46	0.08	3.3e-09	-5.3	5.8	5.1e-09	0.15	0.19	0.81	FALSE
23	The Cancer Genome Atlas	Brain Lower Grade Glioma	CTSZ	0.04	0.01	blup	50	0.01	1.7e-02	-4.8	5.9	3.3e-09	0.12	0.09	0.46	TRUE
24	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	TH1L	0.12	0.07	blup	46	0.11	2.2e-12	-5.4	5.6	2.8e-08	0.15	0.07	0.93	FALSE
25	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	TH1L	0.07	0.00	blup	46	0.02	2.8e-02	-5.5	6.8	9.1e-12	0.25	0.02	0.43	TRUE
26	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	TH1L	0.16	0.00	enet	14	0.08	3.4e-04	-5.5	6.1	7.8e-10	0.19	0.02	0.41	FALSE
27	The Cancer Genome Atlas	Skin Cutaneous Melanoma	ZNF831	0.22	0.03	enet	6	0.15	9.0e-05	13.5	-9.9	5.3e-23	-0.69	0.01	0.69	TRUE
28	The Cancer Genome Atlas	Stomach Adenocarcinoma	TH1L	0.05	0.04	lasso	2	0.03	1.9e-03	-5.5	6.0	1.6e-09	0.16	0.15	0.48	FALSE
29	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	CTSZ	0.14	0.04	blup	49	0.08	2.7e-03	-5.5	5.2	1.7e-07	0.04	0.02	0.55	TRUE
30	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	TUBB1	0.13	0.06	blup	50	0.04	2.3e-02	-5.6	6.0	1.8e-09	0.12	0.02	0.45	TRUE