[Hub]/) : Traits : Comparative body size at age 10 : ← →

chr3:49,615,624-51,320,800

Best TWAS P=1.83e-11 · Best GWAS P=4.04e-08 conditioned to 0.0016

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Brain Cerebellar Hemisphere	HYAL3	0.32	0.17	lasso	8	0.10	1.4e-03	4.7	-5.2	1.8e-07	-0.78	0.04	0.47	FALSE
2	GTEx	Brain Cortex	HEMK1	0.16	0.01	enet	19	0.03	6.1e-02	-4.2	6.4	1.9e-10	0.19	0.08	0.29	FALSE
3	GTEx	Brain Cortex	HYAL3	0.43	0.28	lasso	6	0.34	4.9e-10	4.7	-5.2	2.0e-07	-0.72	0.15	0.77	FALSE
4	GTEx	Brain Cortex	NAT6	0.32	0.20	enet	11	0.18	1.3e-05	4.7	5.2	1.8e-07	0.72	0.07	0.73	FALSE
5	GTEx	Brain Frontal Cortex BA9	NAT6	0.27	0.13	enet	4	0.16	6.3e-05	4.7	5.3	1.2e-07	0.82	0.05	0.69	FALSE
6	GTEx	Esophagus Muscularis	RASSF1	0.10	0.00	lasso	7	0.01	8.7e-02	-5.1	-5.5	3.4e-08	-0.11	0.05	0.68	FALSE
7	GTEx	Esophagus Muscularis	SEMA3B-AS1	0.47	0.00	lasso	7	0.00	5.9e-01	-4.8	-5.5	3.8e-08	0.01	0.12	0.41	FALSE
8	GTEx	Heart Left Ventricle	HYAL1	0.23	0.03	enet	26	0.12	5.8e-07	-4.9	-6.3	3.0e-10	-0.55	0.03	0.94	FALSE
9	GTEx	Muscle Skeletal	SEMA3B-AS1	0.17	0.01	lasso	7	0.02	8.3e-03	-4.4	-5.9	2.8e-09	-0.24	0.11	0.77	FALSE
10	GTEx	Nerve Tibial	RASSF1	0.05	0.03	enet	19	0.02	1.0e-02	-5.0	-5.6	2.5e-08	-0.12	0.06	0.89	FALSE
11	GTEx	Nerve Tibial	HYAL3	0.22	0.10	lasso	5	0.08	2.3e-06	4.7	-5.2	2.1e-07	-0.78	0.15	0.84	FALSE
12	GTEx	Skin Not Sun Exposed Suprapubic	CYB561D2	0.08	0.01	enet	7	0.02	2.3e-02	-4.1	5.5	2.9e-08	0.13	0.13	0.46	FALSE
13	GTEx	Skin Sun Exposed Lower leg	CYB561D2	0.13	0.02	lasso	3	0.05	5.7e-05	-4.1	5.2	1.7e-07	0.11	0.34	0.54	FALSE
14	GTEx	Skin Sun Exposed Lower leg	NAT6	0.10	0.05	lasso	6	0.06	7.0e-06	5.5	5.7	1.1e-08	0.92	0.01	0.99	FALSE
15	GTEx	Spleen	CACNA2D2	0.18	0.01	enet	43	0.03	5.4e-02	-4.3	-6.6	3.5e-11	-0.32	0.17	0.27	FALSE
16	ROSMAP	Brain Pre-frontal Cortex	RASSF1	0.03	0.00	bslmm	257	0.02	1.8e-03	-4.2	-6.7	1.8e-11	-0.38	0.04	0.44	TRUE
17	ROSMAP	Brain Pre-frontal Cortex	C3orf18	0.03	0.00	bslmm	232	0.01	2.7e-02	-4.1	-5.8	8.9e-09	-0.15	0.10	0.46	FALSE
18	ROSMAP	Brain Pre-frontal Cortex	HYAL1	0.10	0.04	blup	248	0.04	1.3e-05	-4.6	-5.8	6.9e-09	-0.31	0.14	0.82	FALSE
19	ROSMAP	Brain Pre-frontal Cortex	NAT6	0.28	0.24	lasso	4	0.25	1.6e-31	4.7	5.4	6.9e-08	0.82	0.12	0.87	FALSE
20	YFS	Blood	NAT6	0.09	0.06	bslmm	295	0.06	9.9e-19	4.7	5.9	3.3e-09	0.68	0.18	0.81	FALSE
21	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	C3orf45	0.07	0.05	enet	4	0.05	2.9e-03	-4.6	5.5	4.4e-08	0.46	0.00	0.52	FALSE
22	The Cancer Genome Atlas	Testicular Germ Cell Tumors	CYB561D2	0.08	0.04	blup	17	0.08	9.3e-04	-4.6	5.5	4.4e-08	0.26	0.00	0.33	FALSE