[Hub]/) : Traits : Comparative height size at age 10 :

chr19:41,165,252-42,626,207

Best TWAS P=9.17e-20 · Best GWAS P=2.59e-18 conditioned to 0.238

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ATP5SL 0.34 0.48 bslmm 365 0.48 1.5e-65 8.6 -8.4 4.5e-17 -0.99 0.01 0.99 FALSE
2 CommonMind Brain Pre-frontal Cortex BCKDHA 0.12 0.08 lasso 6 0.10 8.9e-13 8.6 -7.4 1.1e-13 -0.95 0.02 0.98 FALSE
3 GTEx Artery Aorta ATP5SL 0.14 0.00 lasso 2 0.01 1.6e-01 8.4 -8.3 7.2e-17 -0.98 0.03 0.59 FALSE
4 GTEx Artery Aorta B3GNT8 0.14 0.09 lasso 2 0.08 2.6e-05 8.7 7.9 3.1e-15 0.97 0.02 0.98 FALSE
5 GTEx Artery Aorta CTC-435M10.6 0.16 0.14 lasso 3 0.13 1.3e-07 8.6 8.5 1.2e-17 0.99 0.02 0.98 FALSE
6 GTEx Brain Cerebellar Hemisphere B3GNT8 0.38 0.30 lasso 5 0.23 1.1e-06 8.7 8.4 4.1e-17 0.97 0.01 0.98 FALSE
7 GTEx Brain Cerebellar Hemisphere CTC-435M10.6 0.29 0.20 lasso 4 0.18 2.6e-05 8.7 8.8 1.8e-18 0.99 0.02 0.96 FALSE
8 GTEx Brain Cerebellum B3GNT8 0.28 0.23 lasso 5 0.21 9.2e-07 8.7 8.7 4.4e-18 0.99 0.02 0.98 FALSE
9 GTEx Brain Cerebellum CTC-435M10.6 0.18 0.01 lasso 4 0.03 5.1e-02 8.6 8.8 1.0e-18 0.88 0.02 0.87 FALSE
10 GTEx Brain Frontal Cortex BA9 ATP5SL 0.28 0.15 lasso 3 0.10 1.0e-03 8.6 -8.5 1.3e-17 -0.98 0.02 0.94 FALSE
11 GTEx Cells Transformed fibroblasts TMEM91 0.08 0.00 enet 31 0.01 7.4e-02 2.8 5.5 3.7e-08 0.56 0.02 0.81 FALSE
12 GTEx Cells Transformed fibroblasts B3GNT8 0.10 0.02 lasso 2 0.03 2.0e-03 8.4 8.3 9.8e-17 0.98 0.03 0.97 FALSE
13 GTEx Cells Transformed fibroblasts CTC-435M10.6 0.18 0.16 lasso 2 0.15 4.2e-11 8.4 8.5 2.9e-17 0.96 0.02 0.98 FALSE
14 GTEx Colon Transverse B3GNT8 0.21 0.17 lasso 4 0.18 6.7e-09 8.6 8.2 2.4e-16 0.97 0.02 0.98 FALSE
15 GTEx Colon Transverse CTC-435M10.6 0.26 0.19 enet 19 0.22 5.8e-11 8.4 7.5 5.6e-14 0.91 0.02 0.98 FALSE
16 GTEx Esophagus Gastroesophageal Junction CTC-435M10.6 0.23 0.10 enet 17 0.10 1.7e-04 8.7 7.1 1.1e-12 0.87 0.02 0.96 FALSE
17 GTEx Esophagus Muscularis B3GNT8 0.14 0.10 lasso 2 0.16 7.5e-10 -4.3 6.6 3.8e-11 0.90 0.03 0.97 FALSE
18 GTEx Esophagus Muscularis CTC-435M10.6 0.12 0.12 lasso 2 0.10 1.4e-06 8.5 8.4 6.7e-17 0.95 0.02 0.98 FALSE
19 GTEx Heart Atrial Appendage TMEM91 0.12 0.05 lasso 4 0.08 1.7e-04 7.0 6.4 1.9e-10 0.58 0.05 0.69 FALSE
20 GTEx Heart Left Ventricle B3GNT8 0.27 0.04 lasso 7 0.06 3.9e-04 -4.3 5.4 5.6e-08 0.77 0.03 0.97 FALSE
21 GTEx Heart Left Ventricle CTC-435M10.6 0.18 0.02 lasso 4 0.06 4.8e-04 8.6 6.3 3.9e-10 0.83 0.02 0.95 FALSE
22 GTEx Lung CTC-435M10.6 0.13 0.11 lasso 3 0.10 3.3e-08 8.4 8.4 5.0e-17 0.98 0.02 0.98 FALSE
23 GTEx Muscle Skeletal EXOSC5 0.07 0.03 enet 6 0.03 4.1e-04 8.6 8.8 1.1e-18 0.98 0.02 0.98 FALSE
24 GTEx Nerve Tibial B9D2 0.13 0.08 lasso 4 0.06 2.9e-05 6.4 7.1 9.8e-13 0.73 0.07 0.86 FALSE
25 GTEx Nerve Tibial B3GNT8 0.22 0.17 enet 12 0.20 6.6e-14 8.5 7.6 4.0e-14 0.96 0.02 0.98 FALSE
26 GTEx Nerve Tibial CTC-435M10.6 0.18 0.15 lasso 6 0.14 5.5e-10 8.5 8.7 2.9e-18 0.98 0.01 0.99 FALSE
27 GTEx Skin Sun Exposed Lower leg B3GNT8 0.11 0.04 lasso 6 0.05 1.1e-04 -4.3 6.8 8.5e-12 0.92 0.02 0.98 FALSE
28 GTEx Stomach B3GNT8 0.22 0.14 lasso 7 0.12 1.4e-06 8.6 8.5 2.4e-17 0.97 0.02 0.98 FALSE
29 GTEx Stomach CTC-435M10.6 0.23 0.14 lasso 11 0.13 1.0e-06 8.5 7.9 2.6e-15 0.94 0.02 0.98 FALSE
30 GTEx Testis EXOSC5 0.31 0.33 enet 10 0.33 1.8e-15 8.6 8.6 5.6e-18 0.99 0.02 0.98 FALSE
31 GTEx Thyroid EXOSC5 0.14 0.08 lasso 5 0.05 8.4e-05 8.4 8.2 1.8e-16 0.97 0.03 0.96 FALSE
32 GTEx Thyroid B3GNT8 0.09 0.04 enet 17 0.03 1.4e-03 8.7 7.6 4.2e-14 0.84 0.01 0.96 FALSE
33 GTEx Thyroid CTC-435M10.6 0.07 0.03 lasso 2 0.04 7.9e-04 8.7 7.3 2.3e-13 0.89 0.02 0.97 FALSE
34 YFS Blood ATP5SL 0.06 0.02 lasso 12 0.03 1.1e-09 8.6 8.1 7.4e-16 0.85 0.01 0.99 FALSE
35 YFS Blood B9D2 0.03 0.02 enet 16 0.02 5.6e-07 7.0 6.1 1.1e-09 0.57 0.73 0.20 FALSE
36 YFS Blood BCKDHA 0.08 0.05 enet 27 0.06 1.9e-18 8.6 -7.2 5.6e-13 -0.89 0.01 0.99 FALSE
37 YFS Blood TMEM91 0.50 0.05 enet 85 0.25 5.4e-82 3.0 5.2 1.8e-07 0.28 1.00 0.00 FALSE
38 The Cancer Genome Atlas Bladder Urothelial Carcinoma B3GNT8 0.03 0.04 blup 20 0.04 3.2e-04 8.6 8.5 1.6e-17 0.99 0.01 0.96 FALSE
39 The Cancer Genome Atlas Bladder Urothelial Carcinoma BCKDHA 0.02 0.02 lasso 2 0.02 1.5e-02 8.7 -8.7 3.3e-18 -0.99 0.01 0.82 FALSE
40 The Cancer Genome Atlas Breast Invasive Carcinoma B3GNT8 0.04 0.07 blup 20 0.07 1.2e-13 8.4 8.3 1.1e-16 0.98 0.02 0.98 FALSE
41 The Cancer Genome Atlas Colon Adenocarcinoma B3GNT8 0.09 0.13 blup 20 0.11 5.2e-07 8.5 8.2 1.8e-16 0.98 0.02 0.98 FALSE
42 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ATP5SL 0.04 0.03 enet 12 0.03 1.6e-04 8.7 -7.9 2.8e-15 -0.92 0.01 0.98 FALSE
43 The Cancer Genome Atlas Brain Lower Grade Glioma ATP5SL 0.02 0.03 enet 4 0.02 7.0e-04 8.6 -8.6 7.8e-18 -0.99 0.02 0.92 FALSE
44 The Cancer Genome Atlas Brain Lower Grade Glioma EXOSC5 0.04 0.03 lasso 2 0.02 5.8e-03 8.7 8.3 1.5e-16 0.95 0.01 0.74 FALSE
45 The Cancer Genome Atlas Pancreatic Adenocarcinoma B3GNT8 0.15 0.12 blup 20 0.12 1.3e-05 -4.3 6.7 2.7e-11 0.90 0.04 0.93 FALSE
46 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma ATP5SL 0.23 0.05 blup 18 0.05 4.5e-03 8.7 -9.1 9.2e-20 -0.90 0.01 0.85 TRUE
47 The Cancer Genome Atlas Prostate Adenocarcinoma ATP5SL 0.03 0.03 blup 18 0.03 4.1e-04 8.7 -8.7 2.3e-18 -0.99 0.01 0.93 FALSE
48 The Cancer Genome Atlas Rectum Adenocarcinoma B3GNT8 0.39 0.08 blup 20 0.07 1.1e-02 8.7 7.2 5.6e-13 0.85 0.00 0.32 FALSE
49 The Cancer Genome Atlas Thyroid Carcinoma ATP5SL 0.02 0.02 blup 18 0.02 3.5e-03 8.7 -8.5 2.1e-17 -0.99 0.01 0.79 FALSE
50 The Cancer Genome Atlas Thyroid Carcinoma B3GNT8 0.10 0.12 lasso 3 0.11 1.3e-10 8.6 7.8 7.5e-15 0.97 0.01 0.99 FALSE
51 The Cancer Genome Atlas Thyroid Carcinoma EXOSC5 0.02 0.01 blup 31 0.03 4.5e-04 8.4 7.8 4.6e-15 0.96 0.02 0.93 FALSE