TWAS hub - PPIL6

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0830	0.0360	2.1e-04	0.017	0.039	0.025	0.040	0.021	2.9e-03	1.4e-05	4.8e-04	1.2e-05	1.1e-03
2	GTEx	Brain Cerebellum	0.3020	0.0930	2.2e-03	0.144	NA	0.020	NA	0.112	4.8e-05	NA	8.2e-02	NA	3.5e-04
3	GTEx	Brain Cortex	0.2890	0.1070	7.0e-03	0.220	NA	0.140	NA	0.179	9.9e-07	NA	1.1e-04	NA	1.1e-05
4	GTEx	Cells Transformed fibroblasts	0.0650	0.0350	7.7e-03	-0.001	NA	-0.002	NA	-0.003	3.9e-01	NA	4.6e-01	NA	7.3e-01
5	GTEx	Thyroid	0.1690	0.0490	4.5e-07	0.054	NA	0.101	NA	0.115	5.4e-05	NA	3.9e-08	NA	4.4e-09
6	NTR	Blood	0.0217	0.0105	5.6e-04	0.007	0.007	0.006	0.006	0.007	1.6e-03	2.0e-03	2.9e-03	3.0e-03	2.1e-03
7	TCGA	Breast Invasive Carcinoma	0.0529	0.0204	1.5e-10	0.039	0.056	0.059	NA	0.054	1.3e-08	1.3e-11	3.9e-12	NA	2.7e-11
8	TCGA	Brain Lower Grade Glioma	0.0527	0.0289	6.0e-04	0.035	0.021	0.015	NA	0.020	6.6e-05	1.8e-03	7.0e-03	NA	2.0e-03
9	TCGA	Liver Hepatocellular Carcinoma	0.0750	0.0560	8.8e-03	0.028	0.016	0.011	NA	0.013	1.8e-02	5.8e-02	9.4e-02	NA	7.7e-02
10	TCGA	Thyroid Carcinoma	0.0950	0.0390	7.1e-07	0.085	0.072	0.076	NA	0.073	1.1e-08	1.4e-07	7.7e-08	NA	1.4e-07

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Sitting height	9.8	69.5	125.4	-7.0	2.0	4.8	9.7	10.7	-8.1	9.0	8.7	11.2	8.0
Breastfed as a baby	7.6	9.4	17.0	-0.2	3.0	3.8	2.9	3.5	-1.6	4.0	3.6	1.0	4.1
Birth weight	6.1	13.2	24.2	-3.1	-0.5	2.8	4.8	4.9	-1.9	4.1	4.0	4.0	3.8
Trunk fat-free mass	5.5	31.8	71.9	-5.0	0.2	2.1	6.3	7.4	-5.5	5.7	5.8	8.5	5.0
Forced expiratory volume in 1-second (FEV1)	5.5	18.4	55.8	-5.0	-1.1	0.6	3.8	5.4	-4.8	4.1	3.5	7.5	2.4
Trunk predicted mass	5.5	31.5	70.6	-4.9	0.2	2.2	6.3	7.4	-5.5	5.7	5.8	8.4	5.0
Whole body fat-free mass	5.4	30.7	72.4	-4.8	-0.1	1.8	6.2	7.3	-5.6	5.6	5.6	8.5	4.8
Leg fat-free mass (right)	5.4	28.7	69.4	-4.5	-0.2	1.6	6.1	7.0	-5.7	5.4	5.2	8.3	4.5
Whole body water mass	5.4	30.7	73.1	-4.9	-0.1	1.8	6.2	7.2	-5.6	5.5	5.6	8.6	4.7
Peak expiratory flow (PEF)	5.3	12.4	31.3	-4.0	-0.5	1.1	3.3	4.4	-4.4	3.4	3.0	5.6	2.4
Leg predicted mass (right)	5.3	28.4	68.1	-4.5	-0.2	1.6	6.1	7.0	-5.6	5.4	5.2	8.3	4.5
Ever taken oral contraceptive pill	5.2	5.8	10.2	0.6	-1.4	-2.7	-2.5	-3.0	2.4	-3.2	-2.5	-1.7	-2.8
Arm fat-free mass (right)	5.1	26.0	60.7	-4.2	-0.0	1.6	5.9	6.7	-5.2	5.0	5.3	7.8	4.4
Forced expiratory volume in 1-second (FEV1), Best measure	5.0	16.0	47.5	-4.6	-0.9	0.8	3.4	5.0	-4.5	3.9	3.5	6.9	2.4
Arm predicted mass (right)	5.0	25.7	61.8	-4.3	-0.2	1.4	5.8	6.6	-5.2	5.0	5.2	7.9	4.3
Forced vital capacity (FVC)	4.9	18.9	55.2	-5.1	-0.6	0.7	4.0	5.4	-4.9	4.2	3.7	7.4	2.5
Arm fat-free mass (left)	4.9	24.6	57.3	-3.9	0.2	1.7	5.5	6.7	-4.9	5.0	5.3	7.6	4.4
Standing height	4.8	48.0	95.8	-6.4	0.7	3.4	8.2	9.0	-7.0	7.3	6.7	9.8	6.1
Height	4.7	90.2	219.0	-10.7	-2.5	2.8	10.9	12.0	-9.1	8.9	8.6	14.8	7.4
Leg fat-free mass (left)	4.7	24.9	67.6	-4.7	-0.8	0.9	5.5	6.4	-5.2	4.8	4.7	8.2	3.9
Leg predicted mass (left)	4.7	24.7	65.4	-4.5	-0.7	1.0	5.5	6.4	-5.2	4.8	4.7	8.1	4.0
Basal metabolic rate	4.6	25.5	66.6	-4.6	-0.5	1.2	5.6	6.6	-5.2	4.8	4.9	8.2	4.0
Arm predicted mass (left)	4.6	23.5	55.5	-3.7	0.1	1.6	5.4	6.5	-4.8	4.9	5.2	7.5	4.3
Forced vital capacity (FVC), Best measure	4.2	15.2	44.4	-4.7	-0.5	0.6	3.3	4.8	-4.5	3.7	3.5	6.7	2.2
Number of children fathered	4.0	4.6	9.5	0.7	1.6	2.1	1.8	2.6	-1.2	2.5	3.1	1.4	2.9
Alcohol drinker status: Previous	4.0	4.6	11.6	0.4	3.4	3.1	1.5	2.0	-1.3	2.4	2.0	-0.4	2.5
Medication: Ventolin 100micrograms inhaler	3.7	4.8	10.5	-0.4	-0.4	-2.7	-2.5	-3.1	1.1	-2.1	-3.2	-1.4	-2.5
Average weekly fortified wine intake	3.5	4.1	8.8	3.0	-0.1	-1.5	-1.2	-2.2	2.9	-2.4	-1.3	-2.3	-1.7
Family relationship satisfaction	3.4	4.2	10.8	3.0	0.6	-0.3	-1.9	-2.1	3.3	-2.0	-0.5	-2.9	-0.5
Type 2 Diabetes (T2D) (2012)	3.1	3.5	6.7	-1.4	-2.6	-2.6	-1.0	-1.9	1.2	-2.1	-2.0	0.6	-2.3
LDL Cholesterol	3.0	4.8	11.5	3.4	0.7	-0.9	-1.7	-2.3	2.6	-2.4	-1.9	-2.8	-1.7
Wheeze or whistling in the chest in last year	3.0	5.3	8.1	2.6	0.4	-1.2	-2.8	-2.6	2.6	-2.5	-2.0	-2.8	-2.2
Comparative height size at age 10	3.0	16.5	30.7	-3.4	1.5	2.1	4.5	5.2	-4.9	4.5	3.4	5.5	3.7
Friendships satisfaction	3.0	3.7	10.5	2.7	1.4	0.4	-1.8	-1.5	3.2	-1.3	0.6	-3.1	0.1
Happiness	2.9	3.5	10.4	3.2	0.1	-0.4	-1.5	-1.8	3.1	-1.7	-0.2	-2.5	-0.4
Alcohol intake frequency.	2.9	6.7	13.6	-2.5	-0.0	1.1	1.8	3.5	-3.4	3.2	2.2	3.7	2.1
Blood Red Count	2.8	26.8	87.4	-1.8	-9.3	-7.0	-4.5	-2.5	-2.0	-3.0	-6.7	4.1	-5.1
Tinnitus: Yes, but not now, but have in the past	2.8	3.0	6.1	2.4	-0.9	-0.9	-1.7	-1.6	2.5	-2.0	-0.8	-2.0	-1.4
Length of working week for main job	2.8	3.1	9.3	-2.2	1.3	1.5	0.7	1.9	-3.0	1.8	1.3	1.4	1.4
Medication: Levothyroxine sodium	2.7	4.5	7.8	0.4	-2.8	-2.1	-2.0	-2.1	2.2	-2.5	-2.7	-0.5	-2.5
Glaucoma (self-reported)	2.6	3.1	5.7	0.9	2.4	2.4	1.8	1.8	-1.2	2.1	1.7	-0.1	1.8
Hypothyroidism/myxoedema (self-reported)	2.6	5.0	7.8	1.9	-2.4	-1.4	-2.2	-2.1	2.8	-2.4	-2.7	-1.8	-2.3
HbA1C	2.5	2.7	6.9	-1.6	-2.4	-2.6	-0.3	-1.3	-0.5	-1.4	-2.3	1.3	-1.2
Weight	2.5	12.3	38.9	-3.3	-1.6	-0.1	3.7	4.4	-3.8	2.9	3.1	6.2	2.2
Basal cell carcinoma (self-reported)	2.5	3.0	5.4	-0.6	0.7	1.9	1.9	2.3	-2.1	2.3	1.4	1.4	1.7
Bipolar Disorder (2011)	2.4	2.3	7.8	1.9	1.0	0.6	-0.9	-1.3	2.5	-1.2	-0.5	-2.8	-0.7
Respiratory disease	2.4	5.2	10.2	2.4	0.6	-1.0	-2.9	-2.8	2.1	-2.3	-2.2	-3.2	-2.1
Hand grip strength (right)	2.4	6.4	13.0	-0.8	0.9	1.6	2.8	3.6	-1.3	2.8	3.5	3.2	2.7
Forced expiratory volume in 1-second (FEV1), predicted	2.4	5.1	8.8	-1.3	1.3	1.4	3.0	3.0	-1.8	2.2	2.7	2.8	2.3
Ever had bowel cancer screening	2.4	2.8	11.9	3.5	1.7	1.5	-0.8	-0.8	1.4	-0.4	0.2	-2.7	0.4
High blood pressure (mother)	2.3	3.2	5.7	-1.7	-1.6	-2.2	-2.1	-1.7	0.4	-1.9	-2.2	0.3	-2.4
Shortness of breath walking on level ground	2.3	2.7	4.7	0.4	-1.4	-1.9	-2.0	-1.9	1.1	-1.6	-2.2	-0.7	-2.1
Ever had stillbirth, spontaneous miscarriage or termination	2.3	2.5	6.7	-0.9	-1.1	-1.8	-2.6	-1.7	0.3	-1.8	-1.8	-0.3	-1.8
Supplements: Calcium	2.3	2.6	6.8	1.3	2.0	2.6	1.1	1.3	-0.2	1.9	1.6	-0.8	1.9
Hearing difficulty/problems: Yes	2.2	3.4	5.8	0.8	-1.6	-1.8	-1.3	-2.2	2.2	-2.4	-2.2	-1.6	-1.6
Impedance of leg (right)	2.2	10.4	19.3	2.3	-0.5	-1.6	-3.7	-4.2	3.2	-3.6	-3.4	-4.4	-3.2
Guilty feelings	2.2	3.3	7.5	1.7	0.3	-0.9	-1.8	-2.4	2.0	-2.2	-1.3	-2.7	-1.3
Pain type(s) experienced in last month: Hip pain	2.2	2.8	5.4	2.0	-0.3	-0.7	-1.6	-2.1	1.8	-1.6	-1.6	-2.3	-1.7
Rheumatoid Arthritis	2.1	2.9	7.1	-1.3	1.3	1.3	1.3	2.0	-2.7	2.0	1.6	1.8	1.2
Hypothyroidism (self reported)	2.1	4.8	9.5	1.0	-1.8	-1.7	-2.2	-2.4	2.3	-2.5	-3.1	-1.9	-2.5
Diabetes (mother)	2.1	2.7	9.3	-3.1	-1.9	-0.9	1.3	0.9	-2.1	0.5	-0.2	2.5	-0.1
Age when periods started (menarche)	2.1	5.0	13.0	-2.6	-1.4	0.7	2.0	2.9	-1.6	2.3	2.3	3.6	1.5
Pain all over the body in last month	2.1	2.3	4.7	-0.3	1.4	1.4	2.2	1.5	-1.6	1.8	1.6	0.6	1.8
Major Depression (MDD)	2.0	2.4	5.3	1.7	0.1	-0.7	-1.3	-1.7	1.9	-1.9	-1.4	-2.3	-1.4
Body Mass Index (BMI) (2010)	2.0	2.8	9.6	-2.3	-2.6	-1.5	1.1	0.7	-1.1	0.3	-1.0	3.1	-0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.0	2.3	6.6	1.2	-0.6	-0.5	-1.5	-1.7	2.6	-1.8	-1.0	-1.7	-1.3
Impedance of whole body	2.0	10.3	20.9	2.2	-0.4	-1.5	-3.6	-4.3	2.6	-3.4	-3.9	-4.6	-3.3
Age at First Birth	1.9	2.7	5.1	1.7	0.3	-0.9	-2.1	-2.1	2.2	-1.7	-0.8	-2.1	-1.1
Sensitivity / hurt feelings	1.9	3.2	10.4	2.2	-0.1	-0.7	-1.1	-2.0	3.2	-1.9	-0.9	-2.5	-1.1
Impedance of leg (left)	1.9	9.4	23.3	2.9	0.3	-0.9	-3.3	-3.8	3.1	-3.2	-3.0	-4.8	-2.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.9	2.3	6.6	2.5	2.3	1.0	-0.8	-1.1	1.2	-0.2	-0.6	-2.6	0.2
Supplements: Glucosamine	1.8	2.3	7.7	2.8	1.1	0.3	-0.9	-1.5	2.0	-0.5	-0.6	-2.5	-0.2
Had menopause	1.8	2.2	4.4	0.2	0.4	1.5	1.6	2.1	-1.4	2.0	1.5	1.5	1.7
Had major operations	1.8	2.1	5.9	-2.4	-0.3	0.6	1.6	1.4	-1.4	1.4	0.9	2.2	1.1
Blood Eosinophil Count	1.7	13.1	41.5	4.6	3.5	0.5	-3.0	-4.1	4.0	-3.3	-1.4	-6.4	-1.4
Had other major operations	1.7	2.0	5.8	1.3	0.1	-0.2	-1.9	-1.9	0.4	-1.5	-1.6	-2.4	-1.0
Hair/balding pattern: Pattern 3	1.7	2.5	4.2	-1.7	-1.5	-2.0	-1.6	-2.0	0.6	-1.5	-2.0	-0.2	-1.7
Seen a psychiatrist for nerves, anxiety, tension or depression	1.7	2.2	4.1	1.9	1.3	2.0	0.5	1.5	0.6	1.3	1.9	-0.7	2.0
Illnesses of siblings: Diabetes	1.7	2.1	4.1	-0.8	1.0	0.8	2.0	1.7	-1.4	1.5	1.3	2.0	1.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.7	3.5	13.4	-2.5	-2.4	-0.9	0.7	1.6	-2.1	1.0	0.7	3.7	-0.2
Irritability	1.7	2.9	5.9	2.3	0.4	-0.4	-2.0	-1.9	2.1	-2.0	-0.8	-2.4	-1.0
Severe depression (siblings)	1.6	1.8	5.0	2.2	1.6	1.7	0.0	0.5	1.0	0.9	1.0	-1.7	1.1
Impedance of arm (left)	1.6	7.6	14.0	1.4	-0.9	-1.6	-3.1	-3.7	2.0	-2.8	-3.6	-3.5	-3.0
Age at first live birth	1.6	2.9	10.2	1.9	1.2	-0.1	-0.9	-1.8	2.8	-1.3	0.0	-3.2	-0.2
Illnesses of father: Heart disease	1.6	2.2	4.6	0.8	-0.4	-1.7	-1.0	-2.1	1.0	-1.9	-1.9	-1.2	-1.6
Lung FVC	1.5	7.6	24.5	-2.0	-0.3	0.5	2.4	3.8	-3.0	2.9	2.6	4.9	1.4
Health satisfaction	1.5	1.9	3.8	1.9	-0.3	-0.5	-1.5	-1.6	1.7	-1.4	-0.9	-1.9	-0.9
Age at last live birth	1.5	2.2	6.1	1.1	0.4	-1.0	-1.1	-2.1	1.6	-1.7	-1.1	-2.5	-1.0
Leg pain on walking	1.5	1.9	5.2	0.0	-0.8	-1.5	-2.3	-1.3	1.6	-1.4	-1.2	-0.0	-1.7
Osteoporosis (self-reported)	1.5	1.8	4.2	-1.4	-2.1	-1.5	-0.4	-1.1	-0.8	-1.4	-1.8	0.3	-1.4
Crohns Disease (2012)	1.4	2.3	5.2	-2.3	-1.5	-2.0	-0.7	-1.2	0.2	-1.5	-1.8	1.0	-1.9
Neuroticism (2016)	1.4	2.0	6.1	-0.2	-1.1	-1.3	-1.3	-1.7	2.5	-1.9	-0.9	-0.9	-1.1
Multivitamins +/- minerals	1.4	1.8	3.5	0.2	-0.7	-1.4	-1.6	-1.5	1.9	-1.8	-1.1	-0.6	-1.6
Medication: Atenolol	1.4	1.7	5.8	-1.3	0.2	0.1	1.5	1.3	-2.4	1.3	0.6	1.8	1.0
Hearing difficulty/problems with background noise	1.4	2.2	4.4	0.7	0.0	-1.1	-2.0	-2.0	1.3	-1.7	-1.5	-2.1	-0.9
Medication: Simvastatin	1.4	2.0	8.7	3.0	0.8	-0.4	0.1	-1.4	1.4	-1.3	-0.5	-2.1	-0.5
Neuroticism score	1.4	3.0	7.9	1.6	-0.8	-1.0	-1.8	-1.8	2.8	-2.3	-1.0	-1.7	-1.4
Exposure to tobacco smoke at home	1.4	1.6	4.8	1.2	1.0	2.2	0.5	1.2	-0.4	1.5	1.2	-0.6	1.6
Mouth/teeth dental problems: Bleeding gums	1.4	1.8	5.5	2.0	2.3	1.2	0.3	-0.4	0.2	0.5	0.4	-2.2	1.1
Heart disease (mother)	1.4	1.7	6.9	2.6	1.9	1.1	0.4	-0.2	1.1	0.1	0.6	-1.9	0.6
Handedness (chirality/laterality): Left-handed	1.4	1.7	5.4	-2.3	-0.2	-0.4	0.9	1.2	-1.7	0.9	0.3	2.2	0.2
Osteoarthritis (self-reported)	1.4	1.8	10.7	3.3	1.3	1.2	-0.0	0.1	0.8	0.5	0.8	-1.4	0.8
Number of self-reported non-cancer illnesses	1.4	2.4	13.4	3.7	1.5	1.6	0.9	0.1	0.4	0.2	0.5	-2.0	1.0
Average weekly champagne plus white wine intake	1.4	1.9	4.2	2.1	1.5	1.9	0.9	0.5	0.1	1.3	1.2	-1.2	1.9
Reaction Time	1.3	2.4	4.0	1.0	-0.6	-0.9	-1.8	-1.9	2.0	-1.5	-1.5	-2.0	-1.5
Chronotype (morning person)	1.3	3.0	9.4	-2.8	-2.4	-1.6	-0.0	0.6	-1.8	0.1	-0.8	3.1	-0.3
Vitamin and mineral supplements	1.3	1.7	2.7	-0.3	0.7	1.2	1.5	1.6	-1.4	1.6	1.4	1.1	1.6
Alcohol usually taken with meals	1.3	2.0	5.6	1.1	-0.5	-0.6	-1.2	-2.0	1.2	-1.6	-1.5	-2.4	-1.1
Impedance of arm (right)	1.3	6.3	11.3	1.2	-0.7	-1.3	-3.1	-3.4	1.7	-2.6	-3.3	-3.2	-2.7
Hip circumference	1.3	5.8	20.2	-3.2	-2.3	-1.2	2.0	2.2	-3.0	1.3	0.9	4.5	0.5
High blood pressure (siblings)	1.3	1.9	3.9	-1.1	0.5	0.9	2.0	1.7	-0.8	1.5	1.6	1.4	1.7
Chest pain or discomfort	1.3	1.9	7.0	2.2	1.7	0.6	-1.0	-0.9	1.2	-0.7	-0.2	-2.7	-0.3
Mood swings	1.3	2.3	7.4	1.1	-0.5	-1.0	-2.2	-1.4	2.7	-1.7	-0.8	-0.9	-1.4
Fractured/broken bones in last 5 years	1.3	1.6	3.4	0.8	0.3	-1.4	-1.9	-1.5	1.1	-1.3	-1.4	-0.8	-1.6
Depressed Affect (Nagel 2018)	1.2	2.4	4.9	1.7	-1.2	-1.2	-2.0	-1.4	2.2	-1.8	-1.1	-1.0	-1.5
Neuroticism (Nagel 2018)	1.2	2.8	5.6	1.7	-1.0	-1.1	-1.9	-1.8	2.4	-2.0	-1.0	-1.7	-1.6
Blood Platelet Count	1.2	14.2	37.2	1.5	1.1	-1.5	-2.7	-5.3	5.0	-4.5	-2.7	-6.1	-3.2
Worry too long after embarrassment	1.2	2.1	4.1	0.5	0.4	-0.7	-1.0	-2.0	1.7	-1.9	-1.4	-1.9	-1.5
Back pain experienced in last month	1.2	1.8	5.1	2.2	1.6	0.6	-0.9	-1.1	1.7	-0.2	0.0	-2.2	-0.0
Medication: Atorvastatin	1.2	1.5	3.0	0.3	1.4	1.4	1.4	1.5	-1.7	1.2	1.2	0.2	1.0
Average weekly beer plus cider intake	1.2	1.7	6.8	-2.6	-1.6	-1.5	-0.1	-0.4	-0.6	-0.9	-1.0	1.3	-1.1
Commuting to job workplace: Cycle	1.2	1.4	4.0	0.6	-0.5	-1.1	-2.0	-1.1	1.4	-1.2	-1.1	-0.5	-1.5
Pack years of smoking	1.2	1.7	6.4	-1.0	-2.5	-1.7	-0.1	-0.5	0.1	-0.8	-1.6	1.0	-1.6
Hand grip strength (left)	1.1	2.9	6.2	-0.0	0.7	1.5	1.6	2.5	-0.6	1.9	2.5	1.7	2.0
Diabetes (father)	1.1	1.4	2.7	0.1	1.6	1.4	0.9	1.1	-1.2	1.4	1.1	-0.1	1.4
Relative age voice broke	1.1	1.6	4.8	2.2	1.3	1.3	0.2	0.3	1.4	0.2	1.4	-1.6	1.0
Past tobacco smoking	1.1	2.0	6.8	-2.0	-2.6	-1.7	-0.3	0.2	-0.6	-0.2	-0.3	2.2	-0.9
Alcohol intake versus 10 years previously	1.1	1.6	4.7	-0.4	-0.5	0.4	1.3	1.8	-1.1	1.4	1.4	2.2	1.1
Frequency of tiredness / lethargy in last 2 weeks	1.1	1.8	4.0	1.0	-0.1	-0.8	-0.6	-2.0	1.2	-1.6	-1.8	-1.9	-1.3
Loud music exposure frequency	1.1	1.2	1.7	-1.0	1.3	1.2	1.3	0.9	-0.9	1.1	1.3	0.3	1.3
Number of full sisters	1.1	1.4	2.8	-0.8	1.6	1.7	0.2	1.4	-0.2	1.4	1.4	0.9	1.1
Qualifications: NVQ or HND or HNC or equivalent	1.1	1.3	5.0	-1.6	-2.2	-1.5	-0.0	-0.4	-0.3	-0.6	-0.8	1.4	-0.7
Risk taking	1.1	1.6	3.8	0.4	1.9	1.4	1.1	1.1	-0.7	1.4	1.7	-0.3	1.7
Diastolic blood pressure, automated reading	1.1	3.5	6.9	-2.0	-2.4	-2.6	-0.0	-0.2	-2.6	-0.7	-1.9	2.5	-1.3
Mean Putamen Volume	1.0	1.1	3.1	0.9	-1.1	-0.5	-1.1	-1.0	1.8	-1.3	-0.5	-1.1	-0.8
HDL Cholesterol	1.0	1.6	3.1	0.5	1.8	1.0	1.2	1.4	-1.3	1.4	1.5	0.7	1.2
Other serious medical condition/disability diagnosed by doctor	1.0	1.4	5.4	1.8	0.6	0.9	-1.0	-1.0	1.1	-0.7	-0.2	-2.3	0.3
Medication for hormone replacement therapy	1.0	1.1	3.0	0.9	1.3	0.2	-0.8	-1.2	1.6	-0.8	-0.2	-1.7	-0.3
Pack years adult smoking proportion	1.0	1.5	5.2	-1.1	-2.3	-1.5	0.2	-0.2	-0.1	-0.7	-1.3	1.2	-1.4
Number of incorrect matches in round	1.0	1.6	3.0	1.7	1.6	1.6	0.4	0.9	0.9	1.2	1.6	-0.8	1.3
Arm fat percentage (right)	1.0	3.9	8.3	0.0	-2.9	-2.9	-2.1	-1.7	0.1	-2.2	-2.0	0.2	-2.5
Asthma	1.0	2.1	4.1	2.0	1.0	-0.4	-1.7	-1.6	1.3	-1.2	-1.3	-2.0	-1.1
Tense / ‘highly strung’	1.0	1.7	3.7	1.8	-1.2	-0.3	-1.3	-1.0	1.8	-1.3	-0.4	-1.9	-0.7
Chronic bronchitis/emphysema (mother)	1.0	1.2	2.2	-0.4	1.0	1.4	0.9	1.5	-1.4	1.2	1.0	0.5	1.0
Mouth/teeth dental problems: Loose teeth	1.0	1.2	2.9	1.1	0.3	-0.7	-0.7	-1.5	1.7	-1.1	-1.0	-1.4	-0.8
Arm fat percentage (left)	1.0	3.9	8.9	-0.1	-3.0	-3.0	-1.8	-1.7	0.0	-2.2	-2.0	0.3	-2.5
Medication: Bendroflumethiazide	1.0	1.6	4.5	-0.8	0.5	0.2	2.1	1.2	-1.6	1.0	0.8	1.9	1.0
Heart disease (siblings)	1.0	1.2	6.3	2.5	0.5	-0.3	-0.2	-0.8	1.9	-0.3	-0.3	-1.2	0.1
Coronary Artery Disease (CAD)	0.9	1.1	2.5	0.6	1.0	1.4	1.4	1.1	0.1	0.9	1.6	0.1	1.2
Relative age of first facial hair	0.9	1.9	4.0	1.6	1.7	1.6	0.5	0.9	0.7	1.0	2.0	-1.0	1.8
Time employed in main current job	0.9	1.0	3.3	-1.6	-1.2	-0.3	0.7	0.6	-1.8	-0.0	-0.3	1.3	-0.4
Medication: Amlodipine	0.9	1.3	4.0	-0.6	-0.3	0.6	2.0	1.3	-0.5	1.0	1.5	1.2	1.1
Medication: Gliclazide	0.9	1.0	3.6	-1.9	-0.0	0.9	0.4	1.2	-0.7	1.0	0.8	1.2	0.9
Depression (Nagel 2018)	0.8	1.2	2.2	1.5	-0.2	-0.6	-1.2	-1.3	1.4	-1.1	-0.8	-1.3	-0.8
Alzheimer’s Disease (in father)	0.8	0.8	1.7	0.8	1.3	1.2	0.3	0.9	-0.3	1.0	1.2	0.1	1.1
Alzheimer’s Disease (including proxy)	0.8	1.1	4.1	2.0	1.0	1.0	-0.7	-0.4	1.3	0.4	-0.0	-1.6	0.2
Crohns Disease (2017)	0.8	1.8	4.8	-2.2	-1.0	-1.4	-0.2	-0.3	-1.4	-0.7	-1.6	1.6	-1.6
Ovarian Cancer	0.8	1.1	2.5	1.1	0.2	1.6	0.8	1.1	0.3	0.5	1.6	-0.0	1.5
Townsend deprivation index at recruitment	0.8	1.2	4.3	-1.8	-0.9	-1.0	0.1	0.6	-0.9	-0.1	-0.6	2.1	-0.8
Qualifications: None of the above	0.8	1.8	5.2	-1.3	-0.3	0.9	0.7	1.8	-1.6	1.5	0.7	2.3	0.9
Mouth/teeth dental problems	0.8	1.2	5.8	-2.4	-1.0	-0.5	0.3	0.7	-0.9	0.2	0.2	1.9	-0.2
Illnesses of siblings	0.8	1.1	2.0	-0.5	-1.3	-0.8	-1.4	-1.0	0.4	-1.1	-1.2	-0.5	-1.4
Worrier / anxious feelings	0.8	1.4	3.1	0.1	-1.3	-1.4	-0.8	-1.4	1.6	-1.7	-1.0	-0.4	-1.2
Qualifications: O levels/GCSEs or equivalent	0.8	1.3	5.1	-0.9	-2.2	-1.6	0.1	-0.9	0.2	-1.2	-1.1	0.4	-1.1
Medication for cholesterol, blood pressure or diabetes	0.8	1.4	5.8	-0.1	-1.1	-0.9	-2.4	-0.9	1.3	-0.7	-0.9	-0.2	-1.3
Leg fat percentage (right)	0.8	2.8	6.3	0.8	-2.5	-2.4	-1.6	-1.5	0.7	-2.0	-1.6	-0.0	-1.9
Pulse wave peak to peak time	0.8	0.9	1.9	1.3	1.3	1.2	0.7	0.5	-0.1	0.8	1.4	-0.8	0.7
Emphysema/chronic bronchitis	0.8	0.9	1.8	0.7	0.8	0.9	1.3	1.0	0.1	1.0	1.3	0.2	1.1
Mean time to correctly identify matches	0.8	1.5	2.9	1.4	-0.3	-0.6	-1.3	-1.5	1.2	-1.0	-1.3	-1.7	-1.2
Illness, injury, bereavement, stress in last 2 years	0.8	0.9	2.2	1.1	0.1	1.3	1.5	0.9	-0.4	0.8	0.9	-0.3	1.2
Hypertension (Self-reported)	0.8	2.1	6.8	-0.5	-0.3	0.5	2.6	1.8	-1.8	1.2	0.7	1.8	1.4
Smoking status: Previous	0.8	1.2	4.0	1.7	1.7	0.8	-0.2	-0.7	0.7	-0.4	-0.3	-2.0	0.3
Asthma (self-reported)	0.8	1.6	3.5	1.9	0.8	-0.3	-1.6	-1.4	1.2	-1.0	-1.1	-1.7	-0.9
Schizophrenia vs Biploar Disorder	0.7	0.9	3.4	-1.2	-0.0	0.1	1.0	0.5	-1.8	0.7	-0.3	1.3	0.4
Ulcerative Colitis (UC)	0.7	1.3	3.3	-0.6	1.3	0.5	1.4	1.1	-1.8	1.3	0.7	1.1	0.7
Breast Cancer	0.7	1.7	3.8	-0.3	-0.7	-1.0	-1.4	-1.9	0.9	-1.4	-1.9	-1.6	-1.0
Primary Biliary Cirrhosis	0.7	1.0	4.3	1.6	1.2	0.9	-0.6	-0.6	0.3	-0.5	-0.5	-2.1	0.1
Triglycerides	0.7	1.2	2.7	0.7	-0.0	-0.2	-0.8	-1.5	0.8	-1.5	-1.4	-1.6	-1.0
Cardiovascular Disease	0.7	2.2	6.8	-0.8	0.0	0.6	2.6	1.8	-1.9	1.2	1.0	1.8	1.3
Lung FEV1/FVC ratio	0.7	3.4	8.6	-1.3	-2.2	0.6	2.2	2.5	-1.4	1.6	1.0	2.9	1.0
Number of treatments/medications taken	0.7	1.3	2.9	1.1	1.3	1.7	1.4	1.1	-0.2	0.8	1.2	-0.3	1.3
Systolic blood pressure, automated reading	0.7	2.2	6.9	-1.3	-1.7	-1.3	0.8	0.3	-2.6	-0.0	-1.5	2.2	-0.9
Qualifications: CSEs or equivalent	0.7	0.9	3.9	-1.4	-0.8	-0.9	0.8	0.5	-0.7	0.6	-0.2	2.0	-0.1
Trunk fat mass	0.7	3.0	11.2	-1.5	-2.4	-1.6	1.1	1.4	-2.0	0.5	0.5	3.4	-0.1
Frequency of tenseness / restlessness in last 2 weeks	0.7	1.1	3.5	1.5	0.4	0.7	-1.5	-0.7	1.3	-0.7	-0.1	-1.9	-0.1
Heart attack	0.7	0.9	2.5	1.5	0.8	1.1	-0.2	-0.5	1.1	-0.4	0.3	-1.6	0.3
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.9	2.5	1.6	0.8	1.2	0.0	0.8	1.3	0.3	1.2	-0.3	0.8
Medication: Cholesterol lowering	0.7	1.1	4.0	0.6	1.8	0.7	2.0	0.1	-1.4	0.3	0.5	-0.5	0.7
Prospective memory result	0.7	0.8	2.8	-1.1	-0.9	-0.4	0.9	0.6	-1.7	0.5	-0.0	1.3	0.4
Pulse wave Arterial Stiffness index	0.7	0.8	2.7	-1.7	-1.3	-0.8	-0.1	0.2	-0.4	-0.2	-0.9	1.4	-0.3
Arm fat mass (right)	0.7	2.9	9.9	-1.8	-2.6	-2.2	0.3	0.8	-1.8	-0.2	-0.1	3.1	-0.8
Birth weight of first child	0.7	1.2	3.2	-0.6	-0.8	0.2	1.8	1.3	0.9	0.8	1.2	1.8	0.6
Number of full brothers	0.7	0.9	2.6	-0.2	1.6	1.2	0.3	0.8	-0.6	1.1	1.0	-0.1	1.2
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.8	2.4	1.6	1.2	1.1	0.3	0.2	0.3	0.6	0.4	-0.9	1.3
Medication: Ibuprofen	0.7	0.9	2.6	1.6	0.8	1.2	-0.1	0.6	1.4	0.2	1.0	-0.5	0.7
Mineral and other dietary supplements	0.7	1.0	1.8	-1.2	0.1	0.6	1.1	1.3	-1.2	0.8	1.1	1.3	0.4
Hearing aid user	0.7	0.8	2.4	1.1	0.0	0.3	-0.2	-0.9	1.3	-0.7	-0.9	-1.6	-0.3
High cholesterol (Self-reported)	0.7	1.2	6.7	2.6	1.2	-0.1	1.0	-0.4	0.5	-1.0	0.2	-1.1	-0.0
Ever depressed for a whole week	0.7	0.9	4.4	2.1	0.4	0.5	-0.0	-0.2	1.7	-0.0	0.5	-0.9	0.4
Myopia	0.7	1.1	5.2	-1.4	0.6	-0.1	0.9	0.5	-2.3	0.9	-0.3	1.0	0.4
Schizophrenia (2018)	0.6	1.3	4.0	1.4	2.0	1.6	1.0	0.1	-0.2	0.8	0.4	-1.4	0.8
Alzheimer’s Disease (in mother)	0.6	0.7	1.3	0.8	-0.3	-0.2	-1.2	-0.9	1.1	-0.2	-1.0	-1.0	-0.6
Fasting Glucose	0.6	0.7	2.2	-1.5	-1.0	-0.7	0.9	-0.1	-1.0	-0.3	-0.8	1.1	0.1
Neuroticism	0.6	1.6	6.4	1.6	-0.1	-0.1	-0.9	-1.0	2.5	-1.5	-0.3	-1.3	-0.7
Trunk fat percentage	0.6	2.3	7.5	-0.2	-2.7	-2.5	-0.8	-0.7	-0.6	-1.3	-1.3	1.2	-1.7
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.3	8.0	2.8	0.1	0.2	-1.5	-0.5	1.3	-0.3	-0.1	-1.1	-0.3
High blood pressure	0.6	1.8	6.1	-0.6	-0.4	0.5	2.5	1.6	-1.6	1.1	0.5	1.6	1.3
Nervous feelings	0.6	1.1	2.8	-0.2	-1.4	-1.0	-1.3	-0.9	0.4	-1.1	-1.2	-0.5	-1.7
Pulse rate	0.6	1.1	2.2	-1.5	0.4	0.7	1.1	1.2	-1.2	1.3	0.2	0.9	0.9
Hair/balding pattern: Pattern 4	0.6	1.5	5.2	2.3	1.6	1.7	0.1	0.4	0.5	0.5	0.8	-1.6	0.9
Pulse wave reflection index	0.6	0.8	1.8	-0.5	-1.3	-1.2	-0.8	-0.6	0.7	-1.1	-0.6	0.6	-1.0
Body fat percentage	0.6	2.4	6.8	0.4	-2.6	-2.4	-1.2	-1.1	-0.1	-1.6	-1.5	0.4	-1.9
Neck or shoulder pain in last month	0.6	0.8	1.8	1.3	1.1	1.4	0.5	0.5	0.4	0.9	0.7	-0.9	1.0
Medication: Blood pressure	0.6	1.1	5.0	-0.2	0.1	0.6	2.2	1.1	-1.2	0.5	0.8	0.7	1.1
Migraine (self-reported)	0.6	0.7	1.8	0.6	0.8	1.1	0.6	0.9	-0.0	0.8	1.3	-0.0	1.0
Whole body fat mass	0.6	2.4	8.8	-1.2	-2.4	-1.6	0.9	1.2	-1.6	0.2	0.4	3.0	-0.3
Diabetes diagnosed by doctor	0.6	1.0	2.7	0.4	1.0	1.2	1.6	1.1	-0.4	1.0	0.9	0.0	1.0
Qualifications: nursing, teaching	0.6	1.0	5.1	1.1	1.2	1.2	0.2	-0.2	0.1	0.4	0.3	-2.2	0.5
Arm fat mass (left)	0.6	2.4	8.8	-1.6	-2.3	-1.8	0.5	1.0	-1.8	0.0	0.2	3.0	-0.5
Tinnitus: Yes, now most or all of the time	0.6	0.7	1.5	0.8	1.2	0.9	1.1	-0.0	0.1	0.9	0.1	-0.9	0.9
Medication: Blood pressure	0.6	1.1	2.3	-0.4	0.5	0.4	1.5	1.3	-1.5	1.1	0.9	1.1	1.1
Supplements: Fish oil (including cod liver oil)	0.6	0.8	2.0	0.2	-1.0	-1.1	-1.1	-1.1	0.4	-0.9	-1.4	-0.3	-0.6
Worry (Nagel 2018)	0.5	1.0	3.3	0.1	-1.8	-1.0	-0.7	-0.7	0.8	-1.2	-0.5	-0.3	-1.3
Irritable Bowel Disease (IBD)	0.5	1.3	5.0	-1.7	0.6	-0.3	1.1	0.6	-2.2	0.6	-0.4	1.6	-0.3
Blood White Count	0.5	3.7	18.0	1.7	2.6	1.8	0.3	-1.5	1.4	-1.1	0.5	-4.2	0.2
Frequency of depressed mood in last 2 weeks	0.5	0.6	1.7	0.7	-0.2	-0.5	-1.3	-0.9	0.8	-1.0	-0.7	-1.0	-0.5
Ever used hormone-replacement therapy (HRT)	0.5	0.6	1.8	-0.1	0.4	0.7	0.4	0.8	0.4	0.8	1.4	0.6	1.2
Supplements: Zinc	0.5	0.6	2.0	1.0	1.4	0.6	-0.2	-0.4	0.8	0.0	0.1	-1.2	0.2
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	1.3	0.7	0.5	-0.4	-1.1	-0.8	0.6	-1.1	-0.6	-0.6	-0.8
Waist circumference	0.5	1.9	8.5	-1.0	-1.8	-1.3	1.3	1.3	-1.0	0.5	0.6	2.9	0.0
Hair/balding pattern: Pattern 2	0.5	0.6	2.5	-0.5	-1.6	-0.7	-0.2	-0.1	-0.1	-0.7	-0.8	1.0	-0.7
Medication: Ramipril	0.5	0.7	3.5	-0.6	0.8	0.5	0.6	0.8	-1.9	0.6	-0.0	0.6	0.3
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	1.2	-0.6	-1.1	-1.0	-0.7	-0.6	0.4	-0.6	-0.8	0.6	-0.9
Mouth/teeth dental problems: Dentures	0.5	0.8	2.3	1.0	-1.5	-0.7	-0.8	-0.9	0.8	-0.5	-1.0	-0.4	-0.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.8	3.9	1.3	0.1	0.0	-0.9	-0.5	2.0	-0.4	0.1	-1.2	0.0
Leg fat mass (right)	0.5	2.1	7.7	-0.9	-2.4	-1.7	0.7	1.0	-1.4	-0.0	0.4	2.8	-0.2
Long-standing illness, disability or infirmity	0.5	0.8	2.6	1.6	0.3	1.2	-0.6	0.2	0.8	0.2	0.7	-1.3	0.6
Commuting to job workplace: Public transport	0.5	0.6	2.5	1.1	-0.2	-0.7	0.0	-0.7	1.6	-0.6	-0.0	-0.6	-0.6
Eye problems/disorders: Glaucoma	0.5	0.6	1.6	0.5	0.8	1.3	0.7	0.9	-0.3	1.1	0.6	-0.2	0.5
Medication: Paracetamol	0.5	0.8	2.2	-0.7	-1.5	-1.2	-0.8	-0.1	0.6	-0.7	0.2	1.3	-0.8
Medication: Lisinopril	0.5	0.7	2.7	1.0	1.6	0.7	0.8	-0.4	-0.2	0.1	-0.1	-1.2	0.5
Ever smoked	0.5	0.8	3.6	1.0	1.9	1.2	0.7	0.3	-0.0	0.3	0.4	-1.0	0.6
Leg fat percentage (left)	0.5	1.6	4.0	1.1	-2.0	-1.9	-1.1	-1.1	0.4	-1.4	-1.1	-0.1	-1.4
Cholesterol lowering medication	0.5	0.8	5.3	2.3	-0.4	-0.7	0.5	-0.3	0.6	-0.8	0.1	-0.6	-0.1
Medication: Omeprazole (e.g. Zanprol)	0.5	0.7	3.1	-0.3	-1.8	-1.1	-0.2	-0.4	0.0	-0.5	-1.0	0.7	-0.6
Heart attack/myocardial infarction (self-reported)	0.5	0.6	2.0	1.4	0.7	0.9	-0.2	-0.5	1.0	-0.3	0.2	-1.3	0.1
Leg fat mass (left)	0.5	2.0	7.6	-0.8	-2.2	-1.4	1.0	1.2	-1.6	0.3	0.6	2.8	0.0
Bipolar Disorder (2018)	0.4	0.6	1.8	0.3	-0.3	-0.5	-0.4	-1.0	1.4	-0.9	-0.3	-0.7	-1.0
Verbal and Numeric Reasoning (VNR)	0.4	1.0	2.1	0.5	-0.3	-1.0	-1.2	-1.4	0.9	-1.3	-0.7	-1.1	-0.9
BMI	0.4	2.5	7.4	-0.0	-2.7	-2.6	-1.0	-0.9	-0.2	-1.6	-1.3	1.0	-2.0
Waist Hip Ratio (WHR)	0.4	1.8	7.4	2.7	1.1	0.3	-0.1	-0.5	2.5	-0.8	0.0	-1.5	-0.3
Systolic Blood Pressure	0.4	1.9	6.1	-1.1	-1.1	-0.6	1.7	0.9	-2.5	0.6	-1.0	2.1	-0.5
Current tobacco smoking	0.4	0.7	1.8	-0.5	-1.1	-0.7	-0.8	-0.6	0.9	-0.9	-0.8	-0.2	-1.3
Maternal smoking around birth	0.4	0.5	2.6	1.6	0.6	0.1	0.5	-0.1	1.3	0.0	0.2	-0.1	0.3
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	1.9	-0.1	0.9	0.8	0.5	0.5	-1.4	0.8	0.3	0.5	0.7
Heel bone mineral density (BMD) T-score, automated (right)	0.4	0.9	6.1	2.5	0.3	0.5	-1.1	-0.0	1.0	0.1	0.3	-0.7	0.4
Allergy	0.4	1.0	2.5	-0.5	-0.2	0.8	1.6	1.4	-0.2	0.9	1.1	0.9	1.2
Hayfever/allergic rhinitis (self-reported)	0.4	0.6	2.1	0.8	-0.1	-1.5	0.7	-0.7	0.4	-1.1	-0.3	0.4	-0.7
Father’s age at death	0.4	0.6	1.2	-0.4	-1.1	-0.8	0.0	-1.1	0.6	-0.3	-1.0	-0.9	-0.5
Noisy workplace	0.4	0.4	1.9	-1.4	-0.8	0.0	-0.1	0.7	0.2	0.2	-0.0	1.2	-0.0
Depression (self-reported)	0.4	0.5	1.3	-0.2	0.5	0.6	0.3	1.0	0.5	0.8	1.1	0.6	1.0
Illnesses of mother	0.4	0.5	0.9	-0.2	0.2	0.3	0.6	0.8	-0.7	0.9	0.7	0.9	1.0
Medication: Paracetamol	0.4	0.7	2.4	-0.5	-1.5	-1.0	-0.7	0.4	0.6	-0.3	0.5	1.4	-0.4
Qualifications: College or University degree	0.4	1.1	5.3	0.5	1.7	0.5	-0.6	-1.1	0.6	-0.8	-0.1	-2.3	0.1
Medication: Seretide 50 evohaler	0.4	0.4	1.7	-0.6	-0.2	-0.2	0.6	0.8	-0.5	0.2	0.8	1.3	0.3
Alcohol drinker status: Never	0.4	0.5	1.8	0.1	-0.4	0.1	-0.3	0.9	-1.3	1.0	0.3	0.6	0.7
Unable to work because of sickness or disability	0.4	0.5	3.9	-0.4	0.2	0.2	-2.0	-0.2	0.4	-0.4	-0.2	-0.6	-0.4
Vascular/heart problems diagnosed by doctor	0.4	1.0	3.5	0.7	0.7	-0.0	-1.9	-0.9	1.5	-0.5	0.3	-1.3	-0.7
Bipolar Disorder or Schizophrenia	0.3	0.8	2.4	1.3	1.4	1.0	0.5	-0.5	0.7	0.1	0.1	-1.5	-0.0
Schizophrenia (2014)	0.3	0.7	2.7	0.7	1.4	0.8	0.3	-0.9	0.7	-0.2	-0.5	-1.6	-0.2
Smoking Status	0.3	0.7	3.9	0.5	0.9	0.7	-0.5	-0.7	0.5	-0.4	-0.2	-2.0	-0.4
Fed-up feelings	0.3	0.6	2.1	0.4	-0.7	-0.2	-1.2	-0.3	1.5	-1.0	-0.0	-0.1	-0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	0.8	0.7	0.6	0.9	-0.6	0.3	0.2	0.8	0.5	-0.4	0.8
Taking other prescription medications	0.3	0.4	1.8	1.3	-0.5	0.2	-0.4	-0.3	0.9	-0.7	-0.1	-0.7	-0.1
Hayfever, allergic rhinitis or eczema	0.3	0.6	1.2	-0.3	-0.5	-1.1	-0.8	-1.0	-0.8	-0.9	-0.9	0.4	-1.1
Stomach or abdominal pain in last month	0.3	0.3	1.2	0.4	-0.1	-0.2	-1.1	-0.6	0.1	-0.6	-0.6	-0.7	-0.5
Body mass index (BMI)	0.3	1.3	4.8	-0.7	-2.0	-1.6	0.2	0.6	-0.9	-0.1	0.2	2.2	-0.4
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	1.1	0.7	1.1	0.9	-0.0	0.3	0.7	0.7	0.4	-0.5	0.3
Falls in the last year	0.3	0.4	1.3	0.3	0.5	0.3	-1.1	-0.6	0.5	-0.5	-0.3	-1.1	-0.5
Number of live births	0.3	0.4	1.7	1.3	-0.3	-0.5	-0.7	-0.5	0.2	-0.7	-0.3	-0.7	-0.4
Qualifications: A levels/AS levels or equivalent	0.3	0.6	1.2	-0.8	-0.1	-0.5	-1.1	-1.0	0.0	-0.7	-1.0	-0.9	-0.9
Medication: Lansoprazole	0.3	0.3	1.0	1.0	-0.3	0.7	1.0	0.5	-0.4	0.4	-0.0	0.1	0.4
Ever highly irritable/argumentative for 2 days	0.3	0.3	1.2	0.5	0.6	0.3	-0.4	0.3	1.1	0.1	0.9	-0.1	0.5
Medication: Allopurinol	0.3	0.4	1.4	0.2	1.2	0.5	0.8	0.7	-0.3	0.2	1.0	0.6	0.1
Supplements: Vitamin C	0.3	0.3	1.4	-0.5	0.0	-0.0	0.1	0.6	-1.2	0.5	0.3	0.8	0.4
Loneliness, isolation	0.3	0.4	2.8	1.7	0.0	-0.4	-0.4	-0.4	0.2	-0.1	-0.1	-0.7	0.2
Commuting to job workplace: Walk	0.3	0.3	1.6	-1.3	-0.4	-0.1	0.9	0.1	-0.3	0.2	0.0	0.7	0.3
Eye problems/disorders: Cataract	0.3	0.3	1.6	1.2	-0.0	-0.5	-0.2	-0.4	0.8	-0.6	-0.2	-0.2	-0.6
Medication for cholesterol	0.3	0.5	2.0	-1.4	-1.1	-0.4	-0.7	-0.2	-0.4	-0.0	-0.6	0.6	-0.6
Mother’s age at death	0.3	0.4	2.1	0.6	0.4	0.6	-0.7	-0.4	-0.2	-0.2	0.0	-1.5	-0.1
Intelligence (Savage-Jansen 2018)	0.2	0.5	2.0	0.5	-0.1	0.2	-1.1	-0.8	0.5	-0.6	0.0	-1.4	0.2
Ever had hysterectomy (womb removed)	0.2	0.2	0.4	-0.4	0.6	0.3	-0.0	0.4	-0.5	0.5	0.4	0.6	0.6
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.9	-0.2	-0.8	0.1	-0.3	0.6	-0.2	0.0	0.2	0.9	-0.1
Angina	0.2	0.2	0.6	0.2	0.7	-0.1	-0.0	-0.6	-0.8	-0.3	-0.3	-0.7	0.0
Medication: Co-codamol	0.2	0.2	1.3	-0.4	0.2	-0.5	-0.0	-0.4	-1.1	0.0	-0.3	-0.1	0.2
Serious illness, injury or assault to yourself	0.2	0.2	0.8	0.9	0.6	0.0	-0.4	-0.3	0.0	0.1	-0.3	-0.5	-0.4
Chronic bronchitis/emphysema (father)	0.2	0.3	1.3	-0.4	0.3	0.7	-1.1	0.3	0.4	0.3	0.4	-0.2	0.3
Financial difficulties in last 2 years	0.2	0.3	0.9	-0.9	-0.0	-0.5	-0.2	0.4	-0.6	-0.0	0.1	0.9	-0.1
Diabetes (self-reported)	0.2	0.3	1.1	0.7	0.6	0.6	1.1	0.5	-0.1	0.5	0.3	-0.3	0.4
Fluid intelligence score	0.2	0.4	1.1	0.5	0.1	-0.0	-1.0	-0.7	1.0	-0.5	-0.1	-1.0	-0.4
Lung cancer (father)	0.2	0.3	0.8	0.9	-0.2	0.6	-0.2	0.2	0.8	0.2	0.7	-0.3	0.4
Headache pain in last month	0.2	0.4	2.0	0.2	1.4	0.8	0.2	0.6	-0.4	0.5	0.6	0.1	0.6
Comparative body size at age 10	0.2	0.5	1.1	-0.3	0.7	0.6	-0.3	0.8	-0.2	1.1	1.1	0.4	0.7
Eye problems/disorders: None of the above	0.2	0.2	0.8	-0.6	0.2	0.2	-0.3	-0.4	0.3	-0.1	0.0	-0.9	0.7
Medication for pain relief, constipation, heartburn	0.2	0.4	0.9	-0.2	0.1	-0.5	-0.4	-0.9	-0.5	-0.5	-1.0	-0.8	-0.5
Medication: Omeprazole	0.2	0.3	1.9	0.3	-1.4	-0.3	-0.2	-0.2	0.3	-0.2	-0.4	0.2	-0.1
Suffer from ‘nerves’	0.2	0.3	1.6	0.3	-1.3	-0.5	-0.1	0.4	-0.4	0.1	-0.2	0.6	-0.2
Commuting to job workplace: Car/motor vehicle	0.2	0.2	1.1	0.1	0.2	0.3	0.0	0.4	-1.1	0.6	0.4	-0.1	0.7
Medication: Aspirin	0.2	0.2	1.1	1.0	0.4	-0.1	0.6	-0.1	0.7	-0.2	0.3	-0.2	-0.1
Knee pain experienced in last month	0.2	0.3	1.6	1.3	0.3	0.2	0.5	0.5	0.4	0.5	0.3	0.6	0.3
Average weekly red wine intake	0.2	0.2	0.8	-0.6	-0.1	-0.5	-0.2	-0.9	0.4	-0.5	-0.3	-0.6	0.2
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	0.7	-0.1	-0.8	-0.8	-0.5	0.1	-0.3	-0.7	-0.2	0.7	-0.8
Breast cancer (self-reported)	0.2	0.3	1.1	0.0	0.4	1.1	-0.6	0.5	-0.2	0.6	0.6	0.0	0.5
Medication: Aspirin	0.2	0.3	1.6	1.2	0.4	-0.3	0.4	-0.2	0.9	-0.3	0.3	-0.2	-0.2
Illnesses of father: None of the above (group 1)	0.2	0.3	0.7	0.5	0.1	0.7	0.3	0.8	0.5	0.6	0.8	0.2	0.5
Miserableness	0.2	0.3	1.4	0.2	0.4	0.1	-1.2	-0.3	1.1	-0.4	-0.1	-0.4	-0.3
Wears glasses or contact lenses	0.2	0.2	0.7	0.3	0.1	0.3	0.0	0.3	0.0	0.8	0.4	0.5	0.8
Financial situation satisfaction	0.2	0.3	0.7	0.4	-0.6	0.4	-0.4	0.3	0.7	0.3	0.9	-0.4	0.6
Ever had prostate specific antigen (PSA) test	0.2	0.2	0.9	0.3	-0.1	0.7	0.9	0.2	-0.0	0.4	0.5	-0.1	0.5
Age started oral contraceptive pill	0.2	0.3	1.4	0.5	-1.2	-0.0	-0.1	-0.3	0.7	-0.6	-0.3	-0.5	-0.3
Pain experienced in last month	0.2	0.3	1.6	-1.0	-1.3	-0.3	-0.4	0.2	0.0	-0.4	0.1	0.6	-0.2
Lupus	0.1	0.1	0.7	-0.2	0.9	-0.1	-0.2	-0.4	0.3	-0.2	-0.1	-0.3	-0.2
Ulcerative Colitis	0.1	0.1	0.5	-0.3	0.6	-0.5	0.7	-0.1	-0.1	-0.0	-0.0	0.4	-0.2
Heel T-Score	0.1	0.7	3.2	1.8	-1.1	-0.4	-0.8	0.6	-0.5	-0.0	-0.4	0.7	-0.1
Allergy or Eczema	0.1	0.4	0.8	-0.3	0.1	-0.9	-0.5	-0.7	-0.9	-0.6	-0.5	0.5	-0.8
Type 2 Diabetes (T2D) (2018)	0.1	0.2	1.4	0.3	0.2	0.1	1.2	0.4	-0.2	0.1	-0.0	0.1	0.2
Hair Pigment	0.1	3.3	7.5	2.5	2.1	2.7	1.6	1.4	0.8	1.2	2.1	-0.1	2.0
Tanning	0.1	0.6	1.1	-0.9	-0.1	0.4	0.8	0.9	-1.0	0.9	1.1	0.6	0.7
Average weekly spirits intake	0.1	0.1	0.3	0.5	-0.3	-0.0	-0.1	-0.0	0.5	0.2	0.2	-0.1	0.5
Medication: Metformin	0.1	0.1	0.5	0.3	0.7	0.4	-0.0	-0.0	0.1	-0.1	-0.0	-0.6	-0.3
Blood clot in the leg (DVT)	0.1	0.1	0.6	-0.1	0.6	0.3	-0.0	-0.3	0.1	-0.2	0.3	-0.8	0.1
Gout (self-reported)	0.1	0.2	0.8	-0.2	0.9	-0.0	0.5	0.3	-0.5	-0.1	0.4	0.5	-0.3
Exposure to tobacco smoke outside home	0.1	0.1	0.6	0.6	-0.1	-0.1	-0.2	-0.3	0.4	-0.2	-0.8	-0.4	-0.0
Angina (self-reported)	0.1	0.2	0.7	0.1	0.7	-0.0	0.2	-0.3	-0.9	-0.1	-0.0	-0.5	0.1
Pulse rate, automated reading	0.1	0.2	0.8	-0.7	-0.6	0.1	-0.3	0.2	-0.9	0.3	-0.6	0.2	-0.2
Smoking status: Current	0.1	0.2	1.1	-1.0	-0.6	-0.2	-0.4	0.1	0.1	-0.2	-0.3	0.1	-0.6
Illnesses of father: High blood pressure	0.1	0.1	0.4	-0.4	0.1	0.6	-0.4	0.1	-0.0	0.1	-0.1	-0.3	0.3
Number of operations (self-reported)	0.1	0.1	0.3	0.3	-0.1	0.5	-0.4	-0.4	0.2	-0.1	-0.3	-0.5	-0.1
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Overall health rating	0.0	0.1	0.4	0.6	-0.1	0.6	-0.1	0.1	0.3	0.2	-0.0	-0.3	0.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.0	0.1	0.3	-0.6	0.0	0.1	0.0	-0.2	-0.1	0.2	-0.3	0.2	-0.1
Deep venous thrombosis (DVT) (self-reported)	0.0	0.1	0.3	-0.1	0.3	0.1	0.2	-0.2	-0.1	-0.3	0.2	-0.5	0.0

Hub : Genes

PPIL6

Models

Trait associations