[Hub]/) : Traits : Fed-up feelings :

chr8:8,092,025-11,891,593

Best TWAS P=5.99e-13 · Best GWAS P=4.25e-11 conditioned to 0.232

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum AF131215.2 0.12 0.08 lasso 6 0.06 4.6e-04 -4.5 -5.4 7.3e-08 0.67 0.26 0.71 FALSE
2 GTEx Adrenal Gland AF131215.2 0.20 0.16 enet 12 0.13 2.2e-05 -4.9 -5.2 1.7e-07 0.70 0.28 0.71 FALSE
3 GTEx Adrenal Gland AF131215.9 0.18 0.16 lasso 10 0.18 3.5e-07 -4.9 -5.4 6.6e-08 0.72 0.33 0.66 FALSE
4 GTEx Artery Aorta ERI1 0.11 0.08 lasso 5 0.10 5.1e-06 -5.1 5.3 1.1e-07 -0.72 0.41 0.56 FALSE
5 GTEx Artery Aorta AF131215.2 0.09 0.09 lasso 7 0.08 2.0e-05 4.5 -5.3 1.5e-07 0.70 0.30 0.68 FALSE
6 GTEx Artery Aorta AF131215.9 0.13 0.05 lasso 6 0.07 1.3e-04 -4.7 -5.3 9.4e-08 0.69 0.36 0.62 FALSE
7 GTEx Artery Tibial ERI1 0.05 0.02 lasso 7 0.01 3.2e-02 -5.3 5.5 4.6e-08 -0.76 0.13 0.76 FALSE
8 GTEx Brain Cerebellar Hemisphere FAM86B3P 0.28 0.27 lasso 8 0.28 5.4e-08 -6.5 6.7 2.3e-11 -0.93 0.01 0.99 FALSE
9 GTEx Brain Cerebellar Hemisphere AF131215.2 0.15 0.17 lasso 3 0.09 3.0e-03 5.4 -6.0 1.7e-09 0.63 0.12 0.61 FALSE
10 GTEx Brain Cerebellum FAM86B3P 0.19 0.14 lasso 5 0.16 1.8e-05 -6.3 6.5 6.0e-11 -0.89 0.02 0.98 FALSE
11 GTEx Brain Cortex FAM86B3P 0.14 0.05 enet 9 0.07 5.1e-03 -6.2 6.8 8.3e-12 -0.84 0.05 0.77 FALSE
12 GTEx Brain Frontal Cortex BA9 FAM86B3P 0.16 0.13 enet 27 0.10 1.1e-03 -5.8 7.2 6.0e-13 -0.82 0.02 0.95 TRUE
13 GTEx Breast Mammary Tissue AF131215.2 0.16 0.15 lasso 6 0.12 1.1e-06 4.5 -5.4 5.7e-08 0.73 0.03 0.97 FALSE
14 GTEx Breast Mammary Tissue AF131215.9 0.10 0.10 lasso 8 0.12 8.7e-07 4.6 -5.4 5.5e-08 0.74 0.09 0.90 FALSE
15 GTEx Breast Mammary Tissue (Female) AF131215.2 0.04 -0.01 lasso 2 0.00 4.8e-01 4.6 -5.2 2.1e-07 0.66 0.06 0.22 FALSE
16 GTEx Cells EBV-transformed lymphocytes AF131215.2 0.20 0.10 enet 14 0.11 1.5e-04 5.4 -5.2 1.6e-07 0.69 0.13 0.84 FALSE
17 GTEx Cells Transformed fibroblasts ERI1 0.34 0.35 lasso 7 0.35 1.9e-27 -5.1 5.4 6.2e-08 -0.70 0.44 0.56 FALSE
18 GTEx Cells Transformed fibroblasts FAM86B3P 0.23 0.33 lasso 11 0.38 8.4e-30 -5.9 -6.5 8.6e-11 0.89 0.09 0.91 FALSE
19 GTEx Colon Sigmoid AF131215.2 0.10 0.00 enet 7 0.02 5.0e-02 -5.3 -6.3 3.1e-10 0.74 0.07 0.72 FALSE
20 GTEx Colon Sigmoid AF131215.9 0.11 0.17 enet 5 0.09 4.9e-04 5.5 -5.9 3.4e-09 0.63 0.05 0.88 FALSE
21 GTEx Colon Transverse FAM86B3P 0.13 0.04 lasso 8 0.04 4.4e-03 -6.3 -5.4 5.6e-08 0.84 0.03 0.90 FALSE
22 GTEx Colon Transverse AF131215.9 0.12 0.14 enet 18 0.12 4.0e-06 5.4 -5.5 3.0e-08 0.62 0.08 0.91 FALSE
23 GTEx Esophagus Mucosa FAM86B3P 0.22 0.17 lasso 8 0.19 1.7e-12 -5.9 -5.9 3.2e-09 0.88 0.03 0.97 FALSE
24 GTEx Esophagus Mucosa AF131215.2 0.15 0.14 enet 15 0.18 4.3e-12 5.1 -6.0 2.6e-09 0.69 0.20 0.79 FALSE
25 GTEx Esophagus Mucosa AF131215.9 0.18 0.16 lasso 14 0.19 1.6e-12 -5.2 -5.7 1.4e-08 0.71 0.24 0.76 FALSE
26 GTEx Esophagus Muscularis ERI1 0.12 0.09 enet 13 0.08 7.7e-06 -4.3 6.0 1.7e-09 -0.77 0.19 0.81 FALSE
27 GTEx Esophagus Muscularis AF131215.2 0.10 0.08 lasso 5 0.09 2.3e-06 5.1 -5.7 1.1e-08 0.63 0.25 0.74 FALSE
28 GTEx Esophagus Muscularis AF131215.9 0.14 0.17 enet 16 0.17 1.6e-10 5.5 -5.8 7.3e-09 0.67 0.07 0.93 FALSE
29 GTEx Heart Atrial Appendage AF131215.2 0.39 0.13 enet 26 0.21 6.6e-10 5.1 -5.7 1.2e-08 0.67 0.21 0.79 FALSE
30 GTEx Heart Atrial Appendage AF131215.9 0.24 0.17 enet 26 0.18 1.3e-08 5.1 -5.6 1.8e-08 0.63 0.22 0.78 FALSE
31 GTEx Heart Left Ventricle AF131215.2 0.05 0.01 enet 11 0.01 1.5e-01 -4.6 -5.5 3.9e-08 0.66 0.20 0.56 FALSE
32 GTEx Heart Left Ventricle AF131215.9 0.07 0.10 enet 8 0.10 9.4e-06 5.4 -5.7 1.4e-08 0.65 0.12 0.86 FALSE
33 GTEx Lung ERI1 0.13 0.07 lasso 6 0.09 2.7e-07 4.1 5.4 6.1e-08 -0.74 0.43 0.57 FALSE
34 GTEx Lung AF131215.2 0.12 0.08 lasso 5 0.08 1.0e-06 5.4 -5.5 4.0e-08 0.59 0.08 0.92 FALSE
35 GTEx Lung AF131215.9 0.15 0.18 lasso 4 0.15 1.5e-11 5.4 -5.5 4.9e-08 0.58 0.07 0.93 FALSE
36 GTEx Nerve Tibial AF131215.2 0.19 0.18 lasso 12 0.23 3.5e-16 5.1 -5.6 2.6e-08 0.68 0.19 0.81 FALSE
37 GTEx Nerve Tibial AF131215.9 0.17 0.17 lasso 4 0.18 5.0e-13 5.4 -5.5 3.7e-08 0.59 0.08 0.92 FALSE
38 GTEx Pancreas AF131215.2 0.16 0.16 enet 17 0.15 9.1e-07 5.5 -5.8 6.6e-09 0.69 0.15 0.85 FALSE
39 GTEx Pancreas AF131215.9 0.25 0.24 enet 14 0.22 1.0e-09 -4.7 -5.4 8.7e-08 0.68 0.17 0.83 FALSE
40 GTEx Pituitary FAM86B3P 0.13 0.15 lasso 4 0.13 3.5e-04 5.4 5.6 1.6e-08 -0.78 0.03 0.90 FALSE
41 GTEx Prostate AF131215.2 0.18 0.02 lasso 6 0.02 9.6e-02 -4.5 -5.6 2.8e-08 0.67 0.10 0.40 FALSE
42 GTEx Skin Not Sun Exposed Suprapubic AF131215.2 0.16 0.11 enet 21 0.20 3.9e-11 5.1 -5.6 2.6e-08 0.68 0.22 0.78 FALSE
43 GTEx Skin Not Sun Exposed Suprapubic AF131215.9 0.17 0.14 lasso 8 0.19 9.4e-11 5.4 -5.6 2.2e-08 0.66 0.14 0.86 FALSE
44 GTEx Skin Sun Exposed Lower leg AF131215.2 0.14 0.11 lasso 9 0.16 4.3e-13 5.1 -5.2 2.2e-07 0.64 0.27 0.73 FALSE
45 GTEx Skin Sun Exposed Lower leg AF131215.9 0.19 0.17 enet 29 0.21 3.9e-17 5.4 -6.1 1.2e-09 0.68 0.11 0.89 FALSE
46 GTEx Spleen AF131215.2 0.16 0.08 enet 14 0.06 1.1e-02 5.4 -5.7 1.3e-08 0.68 0.16 0.62 FALSE
47 GTEx Spleen AF131215.9 0.34 0.23 enet 16 0.15 1.2e-04 -4.7 -5.4 7.1e-08 0.66 0.19 0.72 FALSE
48 GTEx Stomach AF131215.9 0.14 0.06 enet 19 0.06 6.7e-04 5.4 -5.1 2.6e-07 0.60 0.14 0.82 FALSE
49 GTEx Testis FAM86B3P 0.15 0.14 lasso 7 0.13 2.2e-06 -6.2 5.9 4.2e-09 -0.86 0.03 0.97 FALSE
50 GTEx Testis SGK223 0.29 0.02 enet 19 0.07 3.5e-04 -5.9 6.5 8.9e-11 -0.71 0.07 0.73 FALSE
51 GTEx Thyroid SGK223 0.19 0.35 enet 16 0.36 1.1e-28 -5.5 6.4 1.6e-10 -0.91 0.62 0.38 FALSE
52 GTEx Thyroid AF131215.2 0.11 0.15 enet 17 0.18 1.2e-13 5.1 -5.7 1.4e-08 0.67 0.13 0.87 FALSE
53 GTEx Thyroid AF131215.9 0.11 0.08 enet 16 0.17 4.7e-13 5.5 -5.5 4.4e-08 0.66 0.09 0.91 FALSE
54 GTEx Uterus AF131215.2 0.17 0.07 enet 13 0.09 7.1e-03 -4.9 -5.7 1.5e-08 0.73 0.10 0.65 FALSE
55 GTEx Uterus AF131215.9 0.16 -0.01 enet 18 0.03 7.5e-02 -5.1 -5.4 5.6e-08 0.65 0.13 0.43 FALSE
56 GTEx Vagina AF131215.9 0.21 0.11 lasso 9 0.08 6.3e-03 -5.1 -5.7 1.4e-08 0.68 0.11 0.79 FALSE
57 NTR Blood MFHAS1 0.02 0.01 blup 759 0.01 2.9e-04 -5.6 -5.4 5.8e-08 0.75 0.39 0.60 FALSE
58 NTR Blood MSRA 0.02 0.01 blup 833 0.01 2.3e-05 -4.4 5.2 1.7e-07 -0.68 0.79 0.19 FALSE
59 ROSMAP Brain Pre-frontal Cortex FAM167A 0.12 0.03 bslmm 620 0.08 1.3e-10 -4.2 5.4 6.9e-08 -0.65 0.06 0.94 FALSE
60 ROSMAP Brain Pre-frontal Cortex XKR6 0.11 0.10 enet 23 0.13 1.2e-16 4.4 -5.3 1.3e-07 0.70 0.21 0.79 FALSE
61 ROSMAP Brain Pre-frontal Cortex FAM86B3P 0.19 0.27 bslmm 331 0.27 5.6e-35 -6.2 6.0 2.2e-09 -0.70 0.03 0.97 FALSE
62 ROSMAP Brain Pre-frontal Cortex SGK223 0.07 0.02 blup 427 0.05 4.3e-07 -2.5 -5.5 3.5e-08 0.68 0.13 0.87 FALSE
63 ROSMAP Brain Pre-frontal Cortex FAM85B 0.16 0.23 enet 18 0.22 1.8e-28 -6.0 6.3 3.4e-10 -0.87 0.04 0.96 FALSE
64 ROSMAP Brain Pre-frontal Cortex AF131215.3 0.08 0.10 lasso 7 0.12 8.3e-16 -5.0 -5.6 2.1e-08 0.72 0.29 0.71 FALSE
65 ROSMAP Brain Pre-frontal Cortex AF131215.2 0.49 0.57 lasso 7 0.57 9.0e-89 5.4 -5.5 3.7e-08 0.59 0.06 0.94 FALSE
66 The Cancer Genome Atlas Bladder Urothelial Carcinoma FLJ10661 0.10 0.16 lasso 1 0.15 6.1e-13 -6.3 -6.3 3.5e-10 0.81 0.00 1.00 FALSE
67 The Cancer Genome Atlas Colon Adenocarcinoma FLJ10661 0.15 0.26 lasso 4 0.23 3.0e-13 -6.3 -6.4 1.4e-10 0.83 0.00 1.00 FALSE
68 The Cancer Genome Atlas Esophageal Carcinoma FLJ10661 0.20 0.23 lasso 2 0.23 5.6e-08 -5.8 -6.0 2.6e-09 0.84 0.01 0.99 FALSE
69 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma FLJ10661 0.07 0.14 lasso 3 0.14 3.7e-15 -6.3 -6.3 3.3e-10 0.82 0.00 1.00 FALSE
70 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma FLJ10661 0.07 0.02 blup 42 0.04 2.9e-03 -5.6 -6.5 8.9e-11 0.83 0.01 0.91 FALSE
71 The Cancer Genome Atlas Brain Lower Grade Glioma FLJ10661 0.21 0.26 lasso 9 0.30 2.3e-34 -6.0 6.6 4.7e-11 -0.83 0.01 0.99 FALSE
72 The Cancer Genome Atlas Liver Hepatocellular Carcinoma FLJ10661 0.09 0.07 blup 41 0.07 3.6e-04 5.1 -5.6 2.8e-08 0.81 0.03 0.72 FALSE
73 The Cancer Genome Atlas Lung Adenocarcinoma FLJ10661 0.06 0.05 lasso 3 0.04 2.4e-05 -5.6 -5.5 4.8e-08 0.78 0.02 0.97 FALSE
74 The Cancer Genome Atlas Lung Squamous Cell Carcinoma FLJ10661 0.12 0.09 lasso 4 0.08 4.7e-09 -6.0 -5.4 8.4e-08 0.77 0.01 0.99 FALSE
75 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma FLJ10661 0.11 0.06 enet 5 0.07 2.3e-05 -6.3 -5.6 1.8e-08 0.78 0.00 0.97 FALSE
76 The Cancer Genome Atlas Pancreatic Adenocarcinoma FAM167A 0.09 0.05 lasso 4 0.08 3.0e-04 -4.6 -5.4 5.6e-08 0.55 0.02 0.64 FALSE
77 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma FLJ10661 0.25 0.18 lasso 4 0.16 4.2e-07 -5.8 6.2 6.6e-10 -0.85 0.01 0.99 FALSE
78 The Cancer Genome Atlas Soft Tissue Sarcoma FLJ10661 0.12 0.00 blup 42 0.00 6.9e-01 -6.3 -5.2 1.7e-07 0.73 0.01 0.54 FALSE
79 The Cancer Genome Atlas Stomach Adenocarcinoma FLJ10661 0.08 0.05 blup 42 0.07 9.3e-06 -5.6 -6.0 1.9e-09 0.84 0.01 0.99 FALSE
80 The Cancer Genome Atlas Testicular Germ Cell Tumors FLJ10661 0.24 0.36 enet 8 0.35 4.1e-13 -6.3 -6.3 3.1e-10 0.83 0.00 1.00 FALSE
81 The Cancer Genome Atlas Thyroid Carcinoma SGK223 0.16 0.20 enet 14 0.22 6.1e-21 5.6 6.4 1.7e-10 -0.88 0.02 0.98 FALSE