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chr3:49,598,064-51,234,774

Best TWAS P=9.61e-08 · Best GWAS P=7.83e-08 conditioned to 1

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
6	GTEx	Nerve Tibial	U73166.2	0.07	0.03	lasso	3	0.03	2.8e-03	5.2	-5.3	9.6e-08	-0.96	0.01	0.98	TRUE
7	GTEx	Thyroid	U73166.2	0.05	0.02	enet	6	0.01	5.9e-02	5.4	-5.3	1.0e-07	-0.98	0.01	0.96	FALSE
8	METSIM	Adipose	CYB561D2	0.09	0.08	lasso	5	0.07	3.8e-10	5.1	-5.3	1.1e-07	-0.85	0.02	0.98	FALSE
9	ROSMAP	Brain Pre-frontal Cortex	CACNA2D2	0.05	0.02	lasso	3	0.02	3.6e-03	5.2	-5.3	1.4e-07	-0.92	0.01	0.98	FALSE
5	GTEx	Muscle Skeletal	SEMA3B-AS1	0.17	0.01	lasso	7	0.02	8.3e-03	5.2	5.3	1.5e-07	0.77	0.03	0.93	FALSE
10	ROSMAP	Brain Pre-frontal Cortex	SEMA3B	0.05	0.03	lasso	6	0.02	8.3e-04	5.1	5.3	1.5e-07	0.88	0.01	0.99	FALSE
4	GTEx	Muscle Skeletal	HYAL1	0.08	0.08	lasso	3	0.06	7.6e-07	5.2	5.2	1.6e-07	0.92	0.01	0.99	FALSE
3	GTEx	Esophagus Muscularis	HYAL1	0.11	0.08	lasso	5	0.05	3.3e-04	5.1	5.2	1.7e-07	0.90	0.01	0.99	FALSE
2	GTEx	Esophagus Gastroesophageal Junction	HYAL1	0.30	0.13	lasso	9	0.10	2.1e-04	5.1	5.2	2.3e-07	0.88	0.01	0.96	FALSE
1	GTEx	Cells Transformed fibroblasts	SEMA3B-AS1	0.15	0.01	enet	3	0.00	3.9e-01	4.8	5.1	3.1e-07	0.86	0.02	0.92	FALSE