[Hub]/) : Traits : Worrier / anxious feelings : ← →

chr16:29,580,611-31,758,245

Best TWAS P=3.89e-08 · Best GWAS P=4.21e-08 conditioned to 0.601

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	RP11-196G11.2	0.23	0.20	lasso	9	0.21	4.2e-17	-5.2	-5.2	1.8e-07	0.67	0.02	0.98	FALSE
2	GTEx	Adipose Visceral Omentum	RP11-196G11.2	0.08	0.07	enet	16	0.08	8.4e-05	-5.2	-5.2	1.5e-07	0.82	0.05	0.94	FALSE
3	GTEx	Artery Aorta	STX1B	0.17	0.18	lasso	6	0.15	1.9e-08	-5.2	-5.2	1.6e-07	0.69	0.02	0.97	FALSE
4	GTEx	Artery Tibial	RP11-196G11.2	0.08	0.04	lasso	4	0.03	3.8e-03	-5.0	-5.2	2.2e-07	0.67	0.03	0.95	FALSE
5	GTEx	Brain Cerebellum	STX1B	0.24	0.16	lasso	11	0.18	4.8e-06	-4.9	-5.1	2.9e-07	0.62	0.05	0.93	FALSE
6	GTEx	Brain Cerebellum	STX4	0.14	0.25	lasso	1	0.24	8.3e-08	-5.2	-5.2	2.6e-07	0.66	0.04	0.95	FALSE
7	GTEx	Brain Cerebellum	RP11-196G11.2	0.31	0.30	lasso	4	0.36	1.3e-11	-5.2	-5.2	1.9e-07	0.67	0.04	0.96	FALSE
8	GTEx	Cells Transformed fibroblasts	RP11-196G11.2	0.14	0.14	lasso	6	0.13	2.9e-10	-5.2	-5.1	3.0e-07	0.69	0.03	0.97	FALSE
9	GTEx	Colon Transverse	RP11-196G11.2	0.24	0.11	lasso	5	0.15	1.9e-07	-5.0	-5.1	3.1e-07	0.67	0.03	0.97	FALSE
10	GTEx	Esophagus Muscularis	STX4	0.05	0.05	lasso	3	0.03	6.7e-03	-5.0	-5.2	2.4e-07	0.69	0.03	0.93	FALSE
11	GTEx	Esophagus Muscularis	RP11-196G11.2	0.14	0.14	lasso	6	0.13	3.7e-08	-5.2	-5.3	1.1e-07	0.75	0.02	0.98	FALSE
12	GTEx	Lung	RP11-196G11.2	0.21	0.12	enet	22	0.14	1.6e-10	-5.1	-5.4	8.1e-08	0.62	0.05	0.95	FALSE
13	GTEx	Muscle Skeletal	STX4	0.04	0.04	lasso	3	0.03	2.9e-04	-5.2	-5.2	1.5e-07	0.70	0.02	0.97	FALSE
14	GTEx	Nerve Tibial	HSD3B7	0.09	0.05	lasso	3	0.03	2.4e-03	-5.1	-5.1	2.6e-07	0.64	0.05	0.80	FALSE
15	GTEx	Testis	STX1B	0.26	0.23	lasso	5	0.25	1.2e-11	-5.2	-5.2	1.7e-07	0.64	0.03	0.97	FALSE
16	GTEx	Testis	RP11-196G11.2	0.14	0.11	lasso	4	0.13	3.1e-06	-5.0	-5.1	2.7e-07	0.68	0.04	0.96	FALSE
17	GTEx	Thyroid	RP11-196G11.2	0.11	0.14	lasso	2	0.14	3.5e-11	-5.1	-5.1	2.7e-07	0.67	0.04	0.96	FALSE
18	METSIM	Adipose	RP11-196G11.2	0.13	0.17	lasso	9	0.16	2.2e-23	-5.1	-5.1	2.6e-07	0.68	0.03	0.97	FALSE
19	ROSMAP	Brain Pre-frontal Cortex	YPEL3	0.06	0.03	blup	209	0.04	1.9e-05	-4.1	-5.2	2.0e-07	0.22	0.01	0.87	TRUE
20	ROSMAP	Brain Pre-frontal Cortex	HSD3B7	0.03	0.05	lasso	6	0.02	3.0e-04	-5.2	-5.4	6.9e-08	0.68	0.03	0.96	FALSE
21	ROSMAP	Brain Pre-frontal Cortex	RP11-196G11.2	0.12	0.12	lasso	4	0.12	1.1e-14	-5.1	-5.1	2.8e-07	0.68	0.03	0.96	FALSE
22	YFS	Blood	STX4	0.03	0.06	lasso	2	0.05	4.3e-17	-5.2	-5.1	2.7e-07	0.70	0.03	0.97	FALSE
23	The Cancer Genome Atlas	Breast Invasive Carcinoma	MYST1	0.05	0.04	blup	34	0.08	2.1e-15	-4.9	-5.2	2.5e-07	0.78	0.04	0.96	FALSE
24	The Cancer Genome Atlas	Breast Invasive Carcinoma	PRSS53	0.03	0.03	blup	38	0.02	6.8e-06	-5.0	5.3	1.2e-07	-0.69	0.01	0.98	FALSE
25	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	MYST1	0.08	0.04	blup	34	0.07	7.2e-08	3.2	-5.5	3.9e-08	0.73	0.04	0.95	TRUE