[Hub]/) : Traits : Worrier / anxious feelings :

chr16:29,580,611-31,758,245

Best TWAS P=3.89e-08 · Best GWAS P=4.21e-08 conditioned to 0.601

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous RP11-196G11.2 0.23 0.20 lasso 9 0.21 4.2e-17 -5.2 -5.2 1.8e-07 0.67 0.02 0.98 FALSE
2 GTEx Adipose Visceral Omentum RP11-196G11.2 0.08 0.07 enet 16 0.08 8.4e-05 -5.2 -5.2 1.5e-07 0.82 0.05 0.94 FALSE
3 GTEx Artery Aorta STX1B 0.17 0.18 lasso 6 0.15 1.9e-08 -5.2 -5.2 1.6e-07 0.69 0.02 0.97 FALSE
4 GTEx Artery Tibial RP11-196G11.2 0.08 0.04 lasso 4 0.03 3.8e-03 -5.0 -5.2 2.2e-07 0.67 0.03 0.95 FALSE
5 GTEx Brain Cerebellum STX1B 0.24 0.16 lasso 11 0.18 4.8e-06 -4.9 -5.1 2.9e-07 0.62 0.05 0.93 FALSE
6 GTEx Brain Cerebellum STX4 0.14 0.25 lasso 1 0.24 8.3e-08 -5.2 -5.2 2.6e-07 0.66 0.04 0.95 FALSE
7 GTEx Brain Cerebellum RP11-196G11.2 0.31 0.30 lasso 4 0.36 1.3e-11 -5.2 -5.2 1.9e-07 0.67 0.04 0.96 FALSE
8 GTEx Cells Transformed fibroblasts RP11-196G11.2 0.14 0.14 lasso 6 0.13 2.9e-10 -5.2 -5.1 3.0e-07 0.69 0.03 0.97 FALSE
9 GTEx Colon Transverse RP11-196G11.2 0.24 0.11 lasso 5 0.15 1.9e-07 -5.0 -5.1 3.1e-07 0.67 0.03 0.97 FALSE
10 GTEx Esophagus Muscularis STX4 0.05 0.05 lasso 3 0.03 6.7e-03 -5.0 -5.2 2.4e-07 0.69 0.03 0.93 FALSE
11 GTEx Esophagus Muscularis RP11-196G11.2 0.14 0.14 lasso 6 0.13 3.7e-08 -5.2 -5.3 1.1e-07 0.75 0.02 0.98 FALSE
12 GTEx Lung RP11-196G11.2 0.21 0.12 enet 22 0.14 1.6e-10 -5.1 -5.4 8.1e-08 0.62 0.05 0.95 FALSE
13 GTEx Muscle Skeletal STX4 0.04 0.04 lasso 3 0.03 2.9e-04 -5.2 -5.2 1.5e-07 0.70 0.02 0.97 FALSE
14 GTEx Nerve Tibial HSD3B7 0.09 0.05 lasso 3 0.03 2.4e-03 -5.1 -5.1 2.6e-07 0.64 0.05 0.80 FALSE
15 GTEx Testis STX1B 0.26 0.23 lasso 5 0.25 1.2e-11 -5.2 -5.2 1.7e-07 0.64 0.03 0.97 FALSE
16 GTEx Testis RP11-196G11.2 0.14 0.11 lasso 4 0.13 3.1e-06 -5.0 -5.1 2.7e-07 0.68 0.04 0.96 FALSE
17 GTEx Thyroid RP11-196G11.2 0.11 0.14 lasso 2 0.14 3.5e-11 -5.1 -5.1 2.7e-07 0.67 0.04 0.96 FALSE
18 METSIM Adipose RP11-196G11.2 0.13 0.17 lasso 9 0.16 2.2e-23 -5.1 -5.1 2.6e-07 0.68 0.03 0.97 FALSE
19 ROSMAP Brain Pre-frontal Cortex YPEL3 0.06 0.03 blup 209 0.04 1.9e-05 -4.1 -5.2 2.0e-07 0.22 0.01 0.87 TRUE
20 ROSMAP Brain Pre-frontal Cortex HSD3B7 0.03 0.05 lasso 6 0.02 3.0e-04 -5.2 -5.4 6.9e-08 0.68 0.03 0.96 FALSE
21 ROSMAP Brain Pre-frontal Cortex RP11-196G11.2 0.12 0.12 lasso 4 0.12 1.1e-14 -5.1 -5.1 2.8e-07 0.68 0.03 0.96 FALSE
22 YFS Blood STX4 0.03 0.06 lasso 2 0.05 4.3e-17 -5.2 -5.1 2.7e-07 0.70 0.03 0.97 FALSE
23 The Cancer Genome Atlas Breast Invasive Carcinoma MYST1 0.05 0.04 blup 34 0.08 2.1e-15 -4.9 -5.2 2.5e-07 0.78 0.04 0.96 FALSE
24 The Cancer Genome Atlas Breast Invasive Carcinoma PRSS53 0.03 0.03 blup 38 0.02 6.8e-06 -5.0 5.3 1.2e-07 -0.69 0.01 0.98 FALSE
25 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma MYST1 0.08 0.04 blup 34 0.07 7.2e-08 3.2 -5.5 3.9e-08 0.73 0.04 0.95 TRUE