Best TWAS P=2.71e-30 · Best GWAS P=4.69e-145 conditioned to 2.75e-31
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | ZNF285 | 0.17 | 0.05 | enet | 20 | 0.07 | 1.3e-04 | -1.26 | -6.5 | 9.7e-11 | -0.09 | 0.39 | 0.15 | TRUE |
| 2 | GTEx | Artery Tibial | CEACAM19 | 0.26 | 0.14 | lasso | 12 | 0.20 | 2.7e-15 | 4.09 | 5.7 | 1.4e-08 | -0.04 | 1.00 | 0.00 | FALSE |
| 3 | GTEx | Esophagus Mucosa | PVRL2 | 0.15 | 0.01 | enet | 10 | 0.02 | 1.7e-02 | -10.25 | 8.8 | 1.1e-18 | -0.16 | 0.14 | 0.04 | FALSE |
| 4 | GTEx | Skin Not Sun Exposed Suprapubic | ZNF229 | 0.28 | 0.09 | enet | 58 | 0.08 | 2.2e-05 | -0.46 | -8.1 | 6.0e-16 | 0.07 | 0.19 | 0.06 | TRUE |
| 5 | GTEx | Stomach | BCAM | 0.33 | 0.00 | enet | 3 | 0.01 | 9.6e-02 | 3.21 | -8.8 | 1.6e-18 | 0.27 | 0.07 | 0.08 | TRUE |
| 6 | YFS | Blood | TOMM40 | 0.04 | 0.00 | bslmm | 371 | 0.01 | 2.6e-04 | -7.66 | 7.4 | 1.3e-13 | -0.08 | 0.05 | 0.02 | TRUE |
| 7 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | CEACAM16 | 0.04 | 0.00 | enet | 6 | 0.02 | 1.4e-03 | -7.15 | 5.5 | 3.8e-08 | -0.04 | 0.03 | 0.03 | TRUE |
| 8 | The Cancer Genome Atlas | Brain Lower Grade Glioma | APOC4 | 0.06 | 0.03 | blup | 34 | 0.04 | 8.4e-06 | 0.16 | 6.0 | 1.6e-09 | -0.19 | 0.66 | 0.06 | TRUE |
| 9 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | APOC1P1 | 0.11 | 0.02 | blup | 38 | 0.04 | 7.6e-03 | -9.14 | -6.2 | 6.3e-10 | 0.01 | 0.03 | 0.03 | FALSE |
| 10 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | APOC2 | 0.18 | 0.12 | enet | 14 | 0.13 | 5.2e-06 | 0.16 | 6.7 | 2.0e-11 | -0.19 | 0.64 | 0.05 | TRUE |
| 11 | The Cancer Genome Atlas | Thyroid Carcinoma | PVRL2 | 0.09 | 0.05 | blup | 55 | 0.03 | 4.6e-04 | 2.48 | -11.4 | 2.7e-30 | 0.31 | 0.46 | 0.09 | TRUE |