[Hub]/) : Traits : Sitting height : ← →

chr7:149,810,606-151,474,607

Best TWAS P=1.31e-18 · Best GWAS P=2.19e-29 conditioned to 0.00123

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	TMEM176A	0.07	0.04	lasso	8	0.03	7.0e-05	7.315	7.8	4.2e-15	0.62	0.64	0.09	FALSE
2	GTEx	Artery Coronary	RP11-148K1.12	0.31	-0.01	enet	16	0.00	2.2e-01	7.428	-6.2	6.8e-10	-0.55	0.02	0.78	FALSE
3	GTEx	Brain Cerebellar Hemisphere	KCNH2	0.34	0.09	lasso	5	0.12	5.0e-04	4.390	-5.5	5.0e-08	-0.06	0.12	0.07	FALSE
4	GTEx	Brain Cerebellar Hemisphere	FASTK	0.46	0.03	lasso	8	0.07	9.3e-03	3.917	5.3	1.2e-07	0.02	0.06	0.06	FALSE
5	GTEx	Brain Cerebellum	KCNH2	0.35	0.20	enet	24	0.28	4.8e-09	-7.663	-6.4	1.5e-10	-0.17	0.87	0.06	TRUE
6	GTEx	Heart Atrial Appendage	TMEM176B	0.37	0.06	enet	15	0.23	1.1e-10	-0.064	-6.0	2.5e-09	-0.42	0.58	0.05	FALSE
7	METSIM	Adipose	AOC1	0.17	0.08	enet	26	0.11	3.2e-16	6.395	8.0	9.8e-16	0.64	0.52	0.48	FALSE
8	ROSMAP	Brain Pre-frontal Cortex	TMEM176A	0.25	0.17	enet	19	0.20	1.5e-25	5.496	8.0	1.5e-15	0.59	1.00	0.00	FALSE
9	ROSMAP	Brain Pre-frontal Cortex	TMEM176B	0.21	0.10	enet	21	0.13	1.0e-16	5.496	5.6	2.7e-08	0.35	1.00	0.00	FALSE
10	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	TMEM176A	0.06	0.01	blup	60	0.03	1.0e-03	7.330	8.5	2.1e-17	0.54	0.06	0.18	FALSE
11	The Cancer Genome Atlas	Breast Invasive Carcinoma	TMEM176A	0.04	0.01	blup	60	0.04	4.0e-08	7.330	6.8	9.9e-12	0.34	0.12	0.16	FALSE
12	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	TMEM176A	0.22	0.01	blup	60	0.14	1.7e-15	1.426	6.2	5.2e-10	0.34	0.92	0.03	FALSE
13	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	TMEM176B	0.21	0.11	blup	72	0.15	2.4e-16	1.426	5.9	3.2e-09	0.20	1.00	0.00	FALSE
14	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ABP1	0.16	0.19	lasso	4	0.20	9.3e-22	-7.533	7.3	1.9e-13	0.64	1.00	0.00	FALSE
15	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	TMEM176A	0.19	0.05	lasso	6	0.13	2.6e-14	-7.533	8.4	4.3e-17	0.64	0.06	0.94	FALSE
16	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	TMEM176B	0.04	0.02	lasso	2	0.02	1.5e-03	3.999	5.5	3.0e-08	0.45	0.05	0.51	TRUE
17	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	TMEM176A	0.17	0.05	blup	60	0.07	5.1e-05	-2.940	6.4	1.6e-10	0.48	0.36	0.27	FALSE
18	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	ABP1	0.26	0.20	enet	10	0.17	1.4e-08	-7.250	-8.6	1.2e-17	-0.55	0.96	0.04	FALSE
19	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	TMEM176B	0.06	0.01	blup	72	0.03	7.7e-05	1.437	5.9	4.3e-09	0.23	0.08	0.16	FALSE
20	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	ATG9B	0.08	0.03	lasso	3	0.03	2.5e-03	-1.103	-5.5	4.4e-08	-0.20	0.01	0.82	FALSE
21	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	ABP1	0.13	0.03	blup	102	0.05	4.4e-03	11.255	-6.2	5.4e-10	-0.59	0.00	0.94	FALSE
22	The Cancer Genome Atlas	Prostate Adenocarcinoma	TMEM176A	0.15	0.01	blup	60	0.04	6.1e-05	10.249	5.8	5.4e-09	0.55	0.06	0.69	FALSE
23	The Cancer Genome Atlas	Stomach Adenocarcinoma	TMEM176A	0.13	0.05	blup	60	0.04	1.3e-03	-2.940	5.5	5.1e-08	0.21	0.03	0.03	FALSE
24	The Cancer Genome Atlas	Testicular Germ Cell Tumors	TMEM176A	0.15	0.00	lasso	10	0.02	5.7e-02	10.249	8.8	1.3e-18	0.66	0.01	0.31	TRUE
25	The Cancer Genome Atlas	Thyroid Carcinoma	TMEM176A	0.32	0.09	blup	60	0.11	6.7e-11	-0.064	6.5	7.9e-11	0.35	1.00	0.00	FALSE