TWAS hub - FASTK

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0790	0.0290	1.0e-03	0.051	0.010	0.027	0.020	0.046	8.1e-07	1.9e-02	2.7e-04	0.00130	2.3e-06
2	GTEx	Adipose Subcutaneous	0.1390	0.0430	4.0e-04	0.080	NA	0.052	NA	0.065	4.5e-07	NA	4.3e-05	NA	5.5e-06
3	GTEx	Artery Aorta	0.1660	0.0580	2.1e-03	0.137	NA	0.106	NA	0.119	5.4e-08	NA	1.9e-06	NA	4.5e-07
4	GTEx	Artery Tibial	0.1271	0.0441	1.1e-03	0.079	NA	0.043	NA	0.070	8.4e-07	NA	2.7e-04	NA	3.6e-06
5	GTEx	Brain Cerebellar Hemisphere	0.4630	0.1240	4.4e-03	0.034	NA	0.033	NA	0.065	4.8e-02	NA	5.0e-02	NA	9.3e-03
6	GTEx	Esophagus Gastroesophageal Junction	0.2040	0.0820	8.4e-03	0.001	NA	-0.004	NA	-0.008	2.9e-01	NA	5.0e-01	NA	8.4e-01
7	GTEx	Esophagus Muscularis	0.1710	0.0500	1.8e-04	0.173	NA	0.132	NA	0.156	1.1e-10	NA	2.2e-08	NA	9.2e-10
8	GTEx	Heart Left Ventricle	0.2618	0.0742	6.0e-04	0.041	NA	0.041	NA	0.040	3.0e-03	NA	3.0e-03	NA	3.3e-03
9	GTEx	Skin Sun Exposed Lower leg	0.1440	0.0460	4.5e-04	0.059	NA	0.030	NA	0.041	1.3e-05	NA	1.6e-03	NA	2.4e-04
10	GTEx	Stomach	0.1580	0.0580	3.3e-03	0.076	NA	0.081	NA	0.080	1.7e-04	NA	1.1e-04	NA	1.1e-04
11	METSIM	Adipose	0.0740	0.0260	1.1e-03	0.045	0.025	0.026	0.024	0.033	2.5e-07	1.1e-04	7.8e-05	0.00013	9.6e-06
12	YFS	Blood	0.0448	0.0129	5.4e-06	0.015	0.021	0.018	NA	0.020	8.1e-06	1.9e-07	1.3e-06	NA	3.6e-07
13	TCGA	Kidney Renal Clear Cell Carcinoma	0.0337	0.0204	9.4e-03	0.021	0.010	0.006	NA	0.020	1.7e-03	2.4e-02	6.2e-02	NA	2.2e-03
14	TCGA	Stomach Adenocarcinoma	0.0460	0.0260	5.9e-03	0.012	0.028	0.013	NA	0.012	4.2e-02	3.7e-03	3.6e-02	NA	4.3e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	7	8	9	10	11	12	13	14
Maternal smoking around birth	6.5	9.5	15.2	-3.6	-3.0	-3.4	-3.5	-2.9	-3.5	-3.9	-3.4	-3.2	-2.7	-2.0	-3.4	-2.5
Fractured/broken bones in last 5 years	5.8	7.5	15.2	-2.8	-2.6	-3.7	-2.1	-2.3	-3.9	-2.5	-3.0	-2.9	-2.2	-2.6	-3.5	-2.0
Serious illness, injury or assault of a close relative in last 2 years	5.6	6.5	11.6	2.1	2.6	2.3	1.7	2.1	2.7	2.5	3.2	3.0	3.2	2.5	2.6	3.4
Heel bone mineral density (BMD) T-score, automated (right)	4.9	11.2	19.0	3.9	3.1	4.1	3.6	2.4	4.4	3.9	3.6	3.4	2.9	2.1	3.9	3.2
Seen a psychiatrist for nerves, anxiety, tension or depression	4.3	5.6	10.3	-2.0	-2.9	-2.3	-1.8	-1.5	-2.2	-2.1	-3.0	-2.9	-3.2	-2.3	-2.4	-2.7
Lung FVC	4.1	20.9	32.7	-5.2	-4.6	-4.6	-5.2	-3.1	-4.7	-3.9	-5.3	-5.1	-4.9	-3.9	-4.8	-5.7
Heel bone mineral density (BMD) T-score, automated (left)	3.9	8.9	13.6	3.1	2.7	3.4	2.8	2.5	3.7	3.2	3.3	3.1	3.0	3.1	3.3	2.8
Mother’s age at death	3.4	4.2	8.7	2.9	1.5	2.2	2.9	2.0	2.2	2.5	2.0	1.7	1.3	1.0	2.2	2.2
Fed-up feelings	3.3	6.0	10.4	-2.1	-3.2	-2.4	-1.8	-2.2	-2.4	-2.5	-2.7	-3.0	-2.8	-2.2	-2.7	-2.6
Chronic bronchitis/emphysema (father)	3.3	3.8	12.6	2.3	1.6	1.9	2.2	3.5	2.3	2.1	1.7	1.8	1.4	0.5	2.1	1.7
Ever had stillbirth, spontaneous miscarriage or termination	3.1	3.3	7.1	1.7	2.7	1.4	1.7	0.6	1.5	1.5	2.1	2.5	2.3	1.9	1.9	1.9
Osteoporosis (self-reported)	3.1	3.8	9.1	-2.4	-1.6	-1.9	-2.3	-1.9	-2.2	-3.0	-1.8	-1.8	-1.4	-1.0	-2.1	-2.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	3.0	3.5	6.7	2.3	1.9	2.6	2.2	0.5	2.2	2.5	1.9	1.8	1.3	0.9	2.2	1.6
Eye problems/disorders: Glaucoma	3.0	3.5	6.6	1.9	1.5	2.6	1.5	2.2	2.4	2.4	1.6	1.6	0.9	2.3	2.3	1.4
Hearing difficulty/problems: Yes	2.9	4.4	9.6	2.9	1.9	2.1	3.1	1.5	2.2	1.7	2.4	2.2	2.1	1.7	2.1	1.9
Osteoarthritis (self-reported)	2.9	3.8	6.3	1.8	2.4	1.7	1.7	1.9	1.8	1.4	2.4	2.5	2.2	1.6	2.1	2.2
Ever depressed for a whole week	2.9	3.6	7.1	2.6	1.5	2.2	2.7	1.4	2.2	1.5	2.0	1.8	1.8	1.0	2.1	1.9
Mean time to correctly identify matches	2.7	5.1	7.6	2.0	2.7	2.5	1.8	2.6	2.4	1.9	2.8	2.7	2.6	1.3	2.5	1.9
Chronotype (morning person)	2.6	6.0	12.4	-3.1	-2.3	-2.8	-3.1	-0.8	-2.8	-3.5	-2.3	-2.3	-1.9	0.7	-2.7	-3.0
Hair/balding pattern: Pattern 3	2.6	3.8	9.8	-2.4	-1.7	-2.2	-2.3	-1.0	-2.1	-2.4	-1.6	-1.8	-1.1	-1.2	-2.2	-3.1
Depressed Affect (Nagel 2018)	2.5	5.2	10.0	-1.4	-3.2	-1.9	-1.1	-2.3	-1.9	-2.4	-2.4	-2.9	-2.7	-2.8	-2.3	-2.6
Average weekly spirits intake	2.4	2.9	6.3	1.7	1.3	2.5	1.2	2.3	2.5	1.3	1.9	1.7	0.9	0.5	2.2	1.9
Frequency of depressed mood in last 2 weeks	2.4	3.4	6.5	-1.1	-2.4	-1.4	-1.0	-2.4	-1.3	-2.6	-1.9	-2.1	-2.1	-2.4	-1.6	-1.7
Allergy or Eczema	2.3	6.0	11.2	2.0	2.6	2.6	1.7	0.5	2.4	2.9	3.0	2.8	2.6	2.9	2.6	3.3
Lung FEV1/FVC ratio	2.3	11.6	19.2	4.4	2.8	4.3	4.2	1.6	4.0	3.3	3.6	3.2	2.9	3.0	3.9	3.8
Neuroticism	2.3	5.6	9.7	-2.2	-3.1	-2.1	-2.1	-2.1	-2.2	-2.8	-2.5	-2.8	-2.5	-1.9	-2.5	-2.7
Neuroticism (Nagel 2018)	2.1	5.0	8.1	-1.9	-2.8	-2.3	-1.6	-2.1	-2.3	-2.8	-2.3	-2.6	-2.2	-2.1	-2.5	-2.1
Tinnitus: Yes, but not now, but have in the past	2.1	2.2	5.2	-0.9	-2.3	-1.2	-0.6	-0.2	-1.3	-0.3	-2.0	-2.2	-2.2	-0.6	-1.6	-2.2
Family relationship satisfaction	2.1	2.6	7.8	-1.6	-1.5	-0.9	-1.8	-0.2	-1.0	-2.5	-1.6	-1.5	-1.5	-2.8	-1.2	-2.0
Miserableness	2.1	3.7	7.2	-1.2	-2.5	-1.9	-0.9	-1.9	-1.8	-1.9	-2.0	-2.3	-2.0	-2.7	-2.0	-2.0
Sitting height	2.0	14.2	28.0	2.6	3.7	4.0	1.7	5.3	3.8	4.2	4.0	4.0	3.5	4.9	4.0	3.8
Breastfed as a baby	2.0	2.5	4.8	2.0	1.0	2.0	1.9	1.1	1.9	2.2	1.7	1.3	1.3	1.4	1.6	1.0
Migraine (self-reported)	2.0	2.5	5.4	0.8	2.3	1.3	0.5	1.4	1.3	1.3	1.9	2.1	2.0	1.8	1.7	2.0
Hand grip strength (left)	1.9	5.0	8.7	-2.8	-2.3	-2.6	-2.7	-0.8	-2.9	-1.6	-2.6	-2.5	-2.2	-0.2	-2.8	-2.3
Pulse wave Arterial Stiffness index	1.9	2.2	5.5	1.5	1.1	1.5	1.5	2.1	1.3	0.8	1.6	1.4	1.7	2.3	1.3	1.6
Age at first live birth	1.9	3.3	6.7	-1.3	-2.5	-1.7	-1.1	-1.8	-1.7	-1.7	-2.0	-2.2	-2.1	-1.1	-2.0	-2.6
Comparative height size at age 10	1.9	10.5	32.5	1.8	3.5	2.9	1.0	4.1	2.8	4.5	3.0	3.3	2.8	5.7	3.2	2.7
Qualifications: nursing, teaching	1.9	2.9	6.0	-1.5	-1.9	-1.9	-1.3	-1.9	-1.7	-1.3	-2.1	-2.1	-1.8	-0.8	-1.8	-2.5
Schizophrenia (2018)	1.8	3.8	12.2	3.1	1.9	1.7	3.5	0.8	1.9	2.2	1.7	1.8	1.6	1.2	2.0	1.4
Impedance of arm (left)	1.8	8.4	15.0	3.4	3.9	2.7	3.5	-1.2	3.0	3.7	2.9	3.3	3.1	-0.9	3.1	2.8
Mood swings	1.8	3.2	9.4	-1.2	-2.4	-1.8	-1.0	-1.1	-1.6	-2.3	-1.5	-2.0	-1.4	-3.1	-1.8	-1.9
Schizophrenia (2014)	1.7	3.7	8.7	2.8	1.7	1.9	2.9	1.1	2.1	1.6	2.0	1.9	1.7	1.9	2.1	1.6
Sensitivity / hurt feelings	1.7	3.0	6.1	-1.8	-2.5	-1.7	-1.7	-1.0	-1.8	-2.0	-1.9	-2.1	-1.6	-0.3	-2.0	-1.8
Had menopause	1.7	2.1	3.6	1.4	1.2	1.9	1.2	1.8	1.9	1.6	1.6	1.4	1.4	0.7	1.7	1.5
Time employed in main current job	1.7	1.9	5.3	1.1	1.1	1.5	1.0	1.3	1.0	1.9	1.1	1.2	1.1	2.3	1.2	2.1
Number of full sisters	1.7	2.1	4.8	2.0	0.6	1.4	2.2	1.8	1.4	1.3	1.2	1.1	1.1	2.0	1.2	1.5
Chest pain or discomfort	1.7	2.5	4.2	1.9	1.4	2.0	1.7	2.0	2.0	1.5	1.4	1.4	0.4	0.6	1.9	1.9
Impedance of whole body	1.7	8.5	16.7	3.2	3.9	2.9	3.3	-1.8	3.2	4.1	2.7	3.1	2.7	-1.8	3.2	2.4
Supplements: Zinc	1.6	1.8	3.3	1.1	1.3	1.5	0.8	1.8	1.5	1.4	1.6	1.4	1.3	0.8	1.4	1.7
Falls in the last year	1.6	2.1	6.2	2.3	0.9	1.6	2.5	1.5	1.6	1.2	1.2	1.2	1.0	0.7	1.6	1.1
Length of working week for main job	1.6	1.8	5.6	-1.7	-1.6	-1.3	-1.8	-0.1	-1.3	-2.4	-1.1	-1.4	-1.1	-0.7	-1.3	-1.0
Birth weight of first child	1.6	2.9	5.2	-1.7	-1.9	-2.0	-1.3	-1.5	-2.3	-0.4	-2.2	-2.0	-2.0	0.8	-2.2	-1.9
Number of full brothers	1.6	2.0	5.6	1.7	1.2	1.1	1.8	2.4	1.2	0.4	1.7	1.4	1.8	0.8	1.1	1.3
Leg pain on walking	1.6	2.0	3.2	1.6	1.0	1.6	1.6	1.5	1.5	1.2	1.8	1.4	1.7	1.4	1.4	1.0
Bipolar Disorder or Schizophrenia	1.5	3.7	8.6	2.7	2.0	1.6	2.9	0.3	1.8	1.8	2.2	2.1	2.3	1.3	1.9	1.9
Breast Cancer	1.5	3.6	8.9	-2.8	-1.5	-2.0	-3.0	-1.8	-2.4	-1.9	-1.7	-1.6	-1.2	-0.6	-2.1	-1.8
Heel T-Score	1.5	11.9	18.7	3.4	4.3	3.2	3.3	2.4	3.9	4.1	3.8	4.0	3.8	2.7	3.6	3.5
Height	1.5	29.3	91.8	4.2	4.7	5.6	3.3	6.5	5.1	7.7	5.1	5.0	4.0	9.6	5.3	3.9
Hayfever, allergic rhinitis or eczema	1.5	3.2	5.9	1.7	1.7	2.0	1.4	-0.3	1.8	1.9	2.1	2.0	1.7	2.4	1.9	2.1
Worry too long after embarrassment	1.5	2.5	4.8	-1.7	-1.9	-2.0	-1.5	-0.8	-2.1	-2.2	-1.5	-1.7	-1.1	-0.3	-2.0	-1.7
Average weekly red wine intake	1.5	2.2	4.3	1.3	1.9	1.5	1.0	0.9	1.8	1.1	2.1	1.9	2.0	0.3	1.9	1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.5	3.2	5.5	-2.4	-1.1	-1.9	-2.3	-1.8	-2.1	-1.7	-1.8	-1.6	-1.5	-1.7	-1.9	-1.9
Rheumatoid Arthritis	1.4	2.0	3.5	-0.6	-1.8	-1.5	-0.0	-0.5	-1.5	-0.4	-1.9	-1.8	-1.7	-1.8	-1.7	-1.8
Medication: Ramipril	1.4	1.8	3.7	-0.8	-1.6	-1.4	-0.5	-1.8	-1.4	-1.2	-1.4	-1.4	-1.2	-1.2	-1.5	-1.9
Neuroticism score	1.4	2.9	6.4	-1.5	-2.5	-1.6	-1.4	-1.0	-1.6	-2.1	-1.6	-2.0	-1.6	-1.3	-1.9	-2.1
Impedance of arm (right)	1.4	6.4	11.0	3.0	3.3	2.3	3.2	-1.4	2.7	3.1	2.5	2.7	2.6	-1.3	2.7	2.3
Mean Putamen Volume	1.3	1.5	2.3	-1.4	-1.4	-1.1	-1.4	-1.0	-1.5	-0.7	-1.5	-1.5	-1.5	-0.2	-1.2	-1.4
Bilateral oophorectomy (both ovaries removed)	1.3	1.5	3.3	0.2	1.8	1.3	-0.1	0.4	0.8	0.7	1.6	1.7	1.8	1.2	1.2	1.7
Medication: Ibuprofen (e.g. Nurofen)	1.3	1.7	4.4	-1.7	-0.8	-1.9	-1.4	-0.5	-2.1	-1.3	-1.0	-0.9	-0.4	0.1	-1.7	-1.7
Standing height	1.3	13.3	44.9	2.3	3.4	3.8	1.5	4.5	3.3	5.2	3.2	3.4	2.4	6.7	3.6	2.9
Medication: Omeprazole	1.3	1.6	3.6	1.0	1.1	1.9	0.6	1.1	1.5	1.2	1.4	1.3	1.0	1.5	1.6	1.4
Smoking status: Previous	1.3	2.0	11.5	1.6	0.5	1.4	1.7	1.3	1.2	1.8	0.7	0.6	0.3	3.4	1.1	0.7
Financial situation satisfaction	1.3	1.7	4.4	2.0	1.1	1.4	2.1	1.0	1.4	1.4	1.2	1.2	0.8	0.3	1.5	1.0
Medication for hormone replacement therapy	1.2	1.4	3.7	0.4	1.7	0.9	0.0	0.6	1.0	0.7	1.7	1.8	1.9	1.1	1.2	1.1
Severe depression (siblings)	1.2	1.3	2.5	1.2	1.1	1.4	1.0	0.3	1.4	1.3	1.6	1.3	1.1	0.9	1.4	1.0
Had other major operations	1.2	1.5	2.9	-1.2	-1.4	-1.1	-1.2	-1.6	-1.1	-1.7	-1.1	-1.2	-1.1	-1.2	-1.2	-1.4
Supplements: Vitamin C	1.2	1.4	2.8	1.5	1.2	1.7	1.4	0.6	1.5	0.6	1.5	1.3	1.3	-0.3	1.4	0.3
Medication: Omeprazole (e.g. Zanprol)	1.2	1.4	3.0	1.2	0.7	1.7	0.9	0.8	1.3	1.5	1.2	1.1	0.7	1.7	1.4	1.2
Depression (Nagel 2018)	1.1	1.6	3.3	-1.0	-1.6	-0.9	-0.9	-1.8	-1.0	-1.5	-1.5	-1.6	-1.6	-0.8	-1.1	-1.3
Coronary Artery Disease (CAD)	1.1	1.3	3.2	-0.8	-1.8	-1.0	-0.6	-1.4	-1.1	-1.3	-1.2	-1.4	-1.4	-0.1	-1.2	-1.4
Hair/balding pattern: Pattern 4	1.1	2.6	5.5	2.3	0.8	2.3	2.2	0.6	2.0	1.5	1.6	1.3	0.9	1.2	1.8	2.0
Qualifications: O levels/GCSEs or equivalent	1.1	1.8	2.9	1.5	1.0	1.6	1.3	1.5	1.7	1.3	1.6	1.3	1.3	0.5	1.6	1.5
Medication: Aspirin	1.1	1.4	3.1	1.3	0.7	1.4	1.2	1.4	1.4	1.2	1.2	1.1	1.0	1.8	1.3	1.0
Knee pain experienced in last month	1.1	1.7	4.2	1.5	1.3	0.9	1.8	2.0	0.8	1.4	1.2	1.3	1.3	1.1	1.0	1.5
Number of self-reported non-cancer illnesses	1.1	2.0	4.2	1.7	0.6	1.1	1.8	1.8	1.2	1.7	1.1	1.0	0.8	2.0	1.1	2.0
Basal cell carcinoma (self-reported)	1.1	1.4	4.6	0.9	1.3	1.2	0.8	1.6	1.1	1.2	1.1	1.2	1.0	2.1	1.1	0.1
Reaction Time	1.0	1.9	4.8	0.7	2.2	1.1	0.5	1.3	1.2	0.7	1.9	2.0	2.2	0.4	1.4	1.2
Verbal and Numeric Reasoning (VNR)	1.0	2.5	5.2	-2.2	-1.1	-2.1	-2.0	-2.2	-2.3	-1.0	-1.5	-1.3	-0.8	-0.4	-2.0	-1.0
HDL Cholesterol	1.0	1.7	3.1	1.7	1.5	1.5	1.8	1.1	1.5	0.7	1.2	1.3	1.1	-0.9	1.5	1.5
Type 2 Diabetes (T2D) (2012)	1.0	1.1	2.5	1.0	0.7	1.5	0.6	0.9	1.6	0.1	1.2	1.1	0.7	1.4	1.5	0.2
Age when periods started (menarche)	1.0	2.3	6.7	2.5	1.0	1.9	2.6	0.9	2.0	1.2	1.2	1.1	0.7	0.9	1.8	1.5
Past tobacco smoking	1.0	1.9	11.5	-1.5	-0.7	-1.1	-1.7	-1.3	-1.0	-1.6	-0.9	-0.8	-0.7	-3.4	-0.9	-0.9
Lung cancer (father)	1.0	1.2	2.9	1.6	1.1	1.4	1.7	1.1	1.1	1.0	0.7	1.0	0.2	0.4	1.3	1.0
Eye problems/disorders: None of the above	1.0	1.1	3.5	-0.7	-1.0	-1.5	-0.4	-0.2	-1.2	-1.3	-1.1	-1.2	-0.8	-1.9	-1.2	-0.5
Worry (Nagel 2018)	0.9	2.0	4.1	-1.5	-1.5	-1.6	-1.3	-1.1	-1.6	-2.0	-1.4	-1.4	-1.1	-1.3	-1.6	-1.1
Age at First Birth	0.9	1.4	3.9	1.8	0.9	1.1	2.0	0.3	1.1	1.2	1.1	1.1	1.0	0.7	1.1	1.5
Triglycerides	0.9	1.5	3.7	-1.9	-0.8	-1.5	-1.9	-1.4	-1.6	-1.2	-0.9	-0.8	-0.6	0.1	-1.4	-1.0
Eye problems/disorders: Diabetes related eye disease	0.9	1.0	4.8	0.9	0.8	0.8	0.9	1.1	0.9	0.8	1.1	1.1	1.1	2.2	0.8	-0.1
Diabetes (father)	0.9	1.1	2.2	-1.2	-1.5	-1.1	-1.1	-1.2	-1.2	-0.7	-1.1	-1.4	-0.7	0.0	-1.2	-1.2
Supplements: Glucosamine	0.9	1.1	2.6	0.5	1.6	0.9	0.3	0.4	1.1	0.7	1.4	1.5	1.5	-1.3	1.1	0.8
Body mass index (BMI)	0.9	3.7	11.8	-1.3	-3.4	-1.4	-1.2	1.3	-1.7	-3.0	-1.9	-2.5	-2.3	1.1	-2.0	-1.0
Impedance of leg (left)	0.9	4.3	9.8	2.1	2.4	2.2	2.2	-2.3	2.3	3.1	1.4	1.7	1.2	-2.7	2.1	1.0
Mouth/teeth dental problems	0.9	1.4	5.0	-0.9	-1.5	-0.7	-0.9	-0.3	-0.7	-0.8	-1.4	-1.5	-1.5	-2.2	-1.0	-1.5
Allergy	0.9	2.1	7.1	-1.2	-0.9	-1.7	-1.0	-0.0	-1.5	-1.5	-1.7	-1.4	-1.3	-2.7	-1.4	-1.8
Mouth/teeth dental problems: Dentures	0.9	1.5	5.0	1.0	1.2	0.7	1.0	2.2	0.7	0.3	1.2	1.2	1.3	1.6	0.9	1.8
Medication: Lansoprazole	0.9	1.0	2.4	1.4	0.6	1.6	1.3	0.9	1.2	1.4	0.8	0.7	0.5	0.6	1.1	0.5
Medication: Amlodipine	0.9	1.2	4.3	-0.5	-1.9	-0.1	-0.6	-0.4	-0.4	-0.9	-1.1	-1.6	-1.7	0.2	-0.8	-2.1
Forced vital capacity (FVC), Best measure	0.9	3.2	9.5	-2.7	-1.3	-1.2	-3.1	-0.5	-1.7	-0.6	-2.1	-1.8	-2.3	0.1	-1.5	-2.6
Pulse wave peak to peak time	0.9	1.1	2.5	-1.1	-0.6	-1.0	-1.2	-1.6	-0.8	-0.3	-1.1	-0.9	-1.3	-1.6	-0.8	-1.1
Health satisfaction	0.9	1.1	3.2	1.7	0.2	1.1	1.8	1.4	1.0	1.0	0.8	0.7	0.6	0.8	1.0	1.0
Emphysema/chronic bronchitis	0.9	1.0	3.3	-1.1	-0.6	-1.1	-1.0	-1.2	-1.1	-0.9	-0.9	-0.8	-0.5	-1.8	-1.0	-1.0
Medication: Ibuprofen	0.9	1.0	2.7	-1.2	-0.7	-1.4	-1.0	-0.3	-1.6	-1.1	-0.6	-0.7	-0.1	0.3	-1.4	-1.6
Friendships satisfaction	0.9	1.1	2.2	1.0	1.0	1.5	0.7	1.2	1.4	0.8	1.1	1.2	0.8	0.9	1.4	0.9
Number of operations (self-reported)	0.9	1.4	2.9	0.8	0.7	1.5	0.4	0.2	1.4	0.4	1.7	1.3	1.4	1.7	1.3	1.5
Cholesterol lowering medication	0.9	1.3	3.8	-1.4	-1.0	-1.3	-1.2	-1.9	-1.4	-1.1	-0.8	-0.9	-0.7	-0.2	-1.4	-1.0
Alzheimer’s Disease (in mother)	0.8	0.9	2.3	1.4	0.3	1.0	1.5	1.3	1.0	0.9	0.6	0.5	0.7	0.6	0.8	1.3
Blood Red Count	0.8	8.0	18.9	-2.4	-4.3	-1.2	-2.5	-1.7	-2.8	-2.5	-3.1	-3.9	-3.6	1.9	-2.7	-3.7
BMI	0.8	4.6	12.3	-1.5	-3.5	-2.1	-1.2	0.1	-2.3	-3.5	-2.1	-2.6	-2.4	1.4	-2.5	-1.1
Waist Hip Ratio (WHR)	0.8	3.5	8.6	-2.0	-2.0	-1.4	-2.0	-1.5	-1.9	-0.9	-2.4	-2.3	-2.9	-0.4	-1.8	-2.4
Impedance of leg (right)	0.8	4.0	9.2	2.0	2.4	2.1	2.0	-2.1	2.3	3.0	1.5	1.7	1.3	-2.7	2.1	0.8
Tense / ‘highly strung’	0.8	1.4	3.7	-1.7	-0.9	-1.3	-1.7	-0.3	-1.3	-1.9	-0.8	-0.8	-0.6	-0.9	-1.3	-1.0
Blood clot in the leg (DVT)	0.8	1.1	2.8	1.0	0.4	1.3	0.8	1.6	1.3	0.4	1.0	0.9	1.1	0.6	1.1	1.7
Exposure to tobacco smoke outside home	0.8	1.1	2.5	-1.3	-0.6	-1.5	-1.1	-0.7	-1.5	-1.6	-1.1	-0.8	-0.7	-0.4	-1.3	-0.6
Forced expiratory volume in 1-second (FEV1), predicted	0.8	1.6	9.3	0.9	1.1	0.9	0.9	1.4	0.9	1.5	0.8	1.1	0.6	3.1	0.9	1.0
Ever taken oral contraceptive pill	0.8	0.9	2.1	1.3	-0.3	1.1	1.2	1.4	1.2	1.1	0.5	0.1	-0.2	1.4	0.8	0.3
Risk taking	0.8	1.2	3.1	-1.0	-1.7	-0.7	-1.1	-0.4	-0.7	-0.4	-1.3	-1.5	-1.8	-0.1	-1.0	-1.6
Hand grip strength (right)	0.7	1.8	3.8	-1.9	-1.0	-1.7	-1.8	-0.4	-2.0	-0.6	-1.4	-1.3	-0.9	1.0	-1.7	-1.4
Average weekly fortified wine intake	0.7	0.8	2.3	0.3	0.5	1.1	-0.1	0.8	1.1	0.7	1.5	1.0	1.5	0.0	0.9	0.8
Hearing difficulty/problems with background noise	0.7	1.1	2.2	1.3	1.2	0.6	1.5	0.4	0.8	0.6	1.4	1.3	1.4	1.4	0.9	0.4
Medication for cholesterol, blood pressure or diabetes	0.7	1.1	2.6	-1.5	-0.2	-1.6	-1.4	-1.3	-1.5	-0.4	-0.6	-0.5	0.0	-0.6	-1.2	-1.2
Gout (self-reported)	0.7	0.9	2.7	-1.6	0.4	-1.3	-1.6	-0.4	-1.3	-0.9	-0.2	0.0	0.9	-1.1	-0.9	0.4
Birth weight	0.7	1.4	2.8	1.5	0.9	1.3	1.5	1.7	1.4	1.4	1.1	1.1	0.9	0.5	1.3	1.2
Comparative body size at age 10	0.7	2.0	7.0	-2.1	-1.3	-1.1	-2.5	-0.3	-1.2	-2.6	-1.0	-1.1	-0.7	-0.6	-1.1	-1.4
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.9	1.8	0.8	1.2	0.9	0.6	0.7	1.0	1.1	0.8	1.1	0.7	1.3	1.1	1.0
Handedness (chirality/laterality): Left-handed	0.7	0.9	2.6	1.5	0.5	1.1	1.6	1.2	0.9	0.7	0.7	0.7	0.4	0.6	1.0	0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.8	2.8	-0.9	0.4	0.8	-1.7	1.4	0.7	-1.4	0.8	0.6	0.3	0.1	0.7	0.8
Medication: Aspirin	0.7	0.9	2.8	1.2	0.2	1.2	1.1	1.1	1.1	0.8	0.7	0.6	0.5	1.7	0.9	0.6
Medication: Gliclazide	0.7	0.8	2.3	-0.7	-1.3	-0.6	-0.7	-0.0	-0.6	-0.3	-1.0	-1.1	-1.1	-1.3	-0.8	-1.5
Pain type(s) experienced in last month: Hip pain	0.7	0.8	4.3	0.4	0.3	1.0	0.2	0.6	0.8	1.4	1.0	0.6	1.0	2.1	0.6	0.6
Medication: Atorvastatin	0.7	0.9	2.6	0.2	-1.3	-0.7	0.6	-1.6	-0.7	-0.8	-1.0	-1.1	-1.2	-1.1	-0.9	-0.9
Illnesses of father: High blood pressure	0.7	0.9	2.3	0.8	0.7	1.1	0.5	0.8	1.3	1.1	1.0	0.8	0.8	1.5	1.1	0.5
Alcohol drinker status: Never	0.7	0.8	4.8	0.3	0.6	-0.2	0.5	1.6	-0.2	0.6	0.4	0.4	1.2	2.2	0.0	1.1
Arm fat-free mass (left)	0.7	3.3	17.8	-1.5	-1.9	-0.2	-2.1	3.4	-0.7	-0.7	-0.9	-1.2	-1.6	4.2	-0.8	-0.8
Major Depression (MDD)	0.6	0.7	3.2	0.0	0.0	-1.8	0.0	-1.6	0.0	-1.6	0.0	0.0	0.0	-1.4	0.0	0.0
Ever used hormone-replacement therapy (HRT)	0.6	0.7	1.8	0.5	0.9	0.9	0.4	0.9	0.7	0.4	1.2	1.1	1.3	0.5	0.7	1.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.8	2.2	-0.7	-1.2	-0.4	-0.9	-0.6	-0.5	-1.5	-0.9	-1.0	-1.5	-0.7	-0.5	-1.2
Waist circumference	0.6	2.1	7.5	-0.7	-2.7	-0.2	-0.9	2.1	-0.7	-1.7	-1.2	-1.8	-2.1	1.8	-1.0	-0.4
Forced vital capacity (FVC)	0.6	2.3	7.1	-2.3	-0.9	-1.3	-2.7	-0.1	-1.6	-0.5	-1.7	-1.4	-1.8	0.8	-1.4	-2.1
Heart attack	0.6	0.8	2.8	-0.3	1.0	0.2	-0.6	0.6	0.1	0.0	1.0	1.0	1.6	1.7	0.3	1.3
Trunk fat-free mass	0.6	3.6	24.8	-1.3	-1.4	0.1	-1.9	3.9	-0.4	-0.2	-0.4	-0.7	-1.2	5.0	-0.4	-0.4
Arm fat mass (right)	0.6	2.5	8.4	-1.1	-2.9	-1.0	-1.1	1.4	-1.3	-2.2	-1.4	-2.0	-1.8	1.6	-1.6	-0.6
Trunk predicted mass	0.6	3.6	24.8	-1.3	-1.4	0.1	-1.9	3.9	-0.4	-0.1	-0.4	-0.7	-1.2	5.0	-0.4	-0.4
Ever highly irritable/argumentative for 2 days	0.6	0.7	3.2	0.0	-1.1	-0.0	0.1	-0.3	-0.1	-0.8	-1.0	-1.1	-1.5	-1.8	-0.3	-0.9
Medication: Ventolin 100micrograms inhaler	0.6	0.7	2.2	-1.0	-0.9	-1.1	-0.9	-1.5	-1.3	-0.2	-0.8	-0.9	-0.1	-0.0	-1.2	-0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	2.1	-1.0	-0.2	-0.8	-1.2	-1.4	-0.7	-0.9	-0.4	-0.3	-0.3	-1.2	-0.5	-1.2
Arm predicted mass (right)	0.6	2.9	19.5	-1.1	-1.3	0.2	-1.6	3.7	-0.4	-0.2	-0.4	-0.6	-1.1	4.4	-0.3	-0.1
Had major operations	0.6	0.7	1.5	0.6	0.8	1.2	0.2	-0.3	1.2	0.5	1.2	1.0	1.1	0.4	1.1	0.9
Whole body fat-free mass	0.6	3.4	25.6	-1.1	-1.3	0.1	-1.6	3.9	-0.4	-0.4	-0.3	-0.6	-1.0	5.1	-0.3	-0.0
Long-standing illness, disability or infirmity	0.6	0.9	2.8	1.6	0.2	1.0	1.7	0.9	1.2	0.8	0.8	0.6	0.1	1.3	1.0	0.6
Mouth/teeth dental problems: Mouth ulcers	0.6	0.9	1.7	-1.0	-1.3	-0.9	-0.9	-0.7	-1.1	-0.9	-1.0	-1.1	-0.9	0.2	-1.1	-1.1
Back pain experienced in last month	0.6	0.8	3.7	0.5	0.5	0.8	0.3	1.8	0.8	0.5	0.9	0.8	0.8	1.9	0.7	-0.1
Mineral and other dietary supplements	0.6	0.8	2.2	-0.2	-1.2	-0.9	0.2	-0.5	-1.0	-0.2	-1.3	-1.2	-1.1	1.5	-1.0	-0.0
Breast cancer (self-reported)	0.6	0.8	2.6	1.1	0.2	1.3	0.9	1.6	1.4	-0.1	0.5	0.4	-0.1	0.1	1.2	0.7
Whole body water mass	0.6	3.5	26.0	-1.0	-1.2	0.1	-1.6	4.0	-0.4	-0.3	-0.3	-0.5	-0.9	5.1	-0.3	0.0
Wears glasses or contact lenses	0.6	0.7	2.8	0.9	0.2	1.1	0.8	0.9	1.0	1.1	0.5	0.4	0.1	1.7	0.9	0.7
Hearing aid user	0.6	0.7	2.2	-0.8	-1.0	-0.7	-0.8	-0.7	-0.7	-1.5	-0.7	-0.9	-0.5	-0.2	-1.0	-0.9
Ever smoked	0.6	1.1	10.2	0.8	0.5	0.5	0.9	0.9	0.5	1.0	0.6	0.5	0.5	3.2	0.4	0.8
Basal metabolic rate	0.6	3.2	22.7	-1.0	-1.6	0.0	-1.4	3.7	-0.5	-0.6	-0.5	-0.8	-1.2	4.8	-0.5	-0.0
Heart attack/myocardial infarction (self-reported)	0.6	0.7	2.8	-0.5	0.9	0.1	-0.8	0.5	-0.1	-0.2	0.9	0.9	1.5	1.7	0.2	1.2
Arm predicted mass (left)	0.6	3.2	18.9	-1.2	-1.8	0.0	-1.8	3.6	-0.5	-0.7	-0.7	-1.0	-1.5	4.3	-0.6	-0.5
Bipolar Disorder (2018)	0.5	0.7	2.9	0.4	0.8	0.3	0.3	-0.5	0.6	0.1	1.5	1.1	1.7	0.5	0.6	1.3
Alzheimer’s Disease (in father)	0.5	0.6	2.0	-1.3	-0.6	-0.7	-1.4	-0.5	-0.9	-0.1	-0.6	-0.7	-0.4	-0.2	-0.8	-0.7
Fasting Glucose	0.5	0.7	1.1	1.1	0.8	1.1	1.1	0.2	0.9	1.1	1.0	0.9	0.7	0.3	0.9	0.2
Other serious medical condition/disability diagnosed by doctor	0.5	0.7	2.3	0.8	-0.2	1.3	0.5	1.2	1.2	0.2	0.6	0.3	-0.1	1.5	1.0	0.7
Systolic blood pressure, automated reading	0.5	1.4	6.1	1.4	-0.2	1.7	1.1	2.5	1.8	0.8	0.7	0.3	-0.2	1.2	1.2	-0.4
Leg fat-free mass (left)	0.5	2.7	22.4	-0.5	-1.0	0.1	-0.9	3.5	-0.4	-0.6	-0.1	-0.3	-0.6	4.7	-0.2	0.6
Leg predicted mass (left)	0.5	2.8	22.0	-0.6	-1.1	0.1	-0.9	3.5	-0.4	-0.6	-0.2	-0.4	-0.7	4.7	-0.3	0.5
Nervous feelings	0.5	1.0	4.4	-1.0	-0.7	-0.9	-1.0	-0.3	-0.9	-2.1	-0.6	-0.6	-0.6	-1.5	-0.9	-1.0
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	2.7	1.0	-0.8	0.5	1.1	-0.5	0.9	-0.1	-0.3	-0.4	-0.7	-1.6	0.5	-0.5
Weight	0.5	2.3	15.4	-0.2	-1.8	0.4	-0.4	3.3	-0.1	-0.5	-0.3	-0.8	-1.1	3.9	-0.3	0.4
Arm fat percentage (right)	0.5	1.8	7.1	-0.7	-2.7	-0.9	-0.5	0.6	-1.1	-2.3	-1.3	-1.9	-1.6	0.3	-1.5	-0.5
Worrier / anxious feelings	0.5	1.0	2.2	-1.0	-1.5	-1.0	-1.0	-0.6	-0.9	-1.2	-1.0	-1.2	-0.9	-0.1	-1.1	-1.2
Medication: Cholesterol lowering	0.5	0.8	2.4	1.2	0.5	1.1	1.1	1.6	1.1	0.4	0.6	0.7	0.1	0.3	1.0	1.0
Arm fat-free mass (right)	0.5	2.8	19.7	-1.1	-1.0	0.2	-1.6	3.7	-0.4	-0.1	-0.2	-0.4	-0.8	4.4	-0.2	0.0
Qualifications: College or University degree	0.5	1.6	3.7	-1.0	-1.3	-1.5	-0.8	-1.9	-1.6	-1.1	-1.4	-1.3	-1.5	0.0	-1.4	-1.3
Suffer from ‘nerves’	0.5	0.8	1.8	-0.8	-0.9	-1.4	-0.5	-0.8	-1.2	-0.9	-1.0	-1.0	-0.8	-0.7	-1.2	-0.9
Commuting to job workplace: Car/motor vehicle	0.5	0.6	1.9	-0.3	-1.2	-0.4	-0.2	-0.3	-0.5	-0.2	-1.0	-1.1	-1.4	-0.1	-0.7	-1.2
Leg fat-free mass (right)	0.5	2.8	22.0	-0.8	-1.1	-0.2	-1.1	3.3	-0.7	-0.8	-0.4	-0.5	-0.8	4.7	-0.5	0.4
Leg predicted mass (right)	0.5	2.7	21.6	-0.8	-1.1	-0.2	-1.1	3.3	-0.7	-0.8	-0.4	-0.5	-0.8	4.7	-0.5	0.4
Arm fat mass (left)	0.5	2.0	6.6	-0.9	-2.6	-0.6	-0.9	1.8	-1.0	-1.9	-1.1	-1.6	-1.6	2.0	-1.2	-0.4
Leg fat percentage (left)	0.5	1.8	7.4	-0.5	-2.7	-0.6	-0.3	0.2	-0.8	-1.8	-1.5	-2.0	-2.0	-0.6	-1.3	-0.4
Commuting to job workplace: Cycle	0.5	0.6	1.6	-0.9	-0.8	-0.8	-0.8	-0.4	-0.9	-1.3	-0.7	-0.8	-0.6	-1.2	-0.8	-0.3
Supplements: Calcium	0.5	0.5	2.4	-0.3	-1.5	-0.6	-0.1	-0.5	-0.6	-0.1	-0.7	-1.1	-0.6	-0.2	-0.9	-1.0
Deep venous thrombosis (DVT) (self-reported)	0.5	0.7	1.9	0.9	0.2	1.0	0.8	1.2	1.1	0.3	0.7	0.6	0.7	0.3	0.8	1.4
Leg fat mass (left)	0.5	1.8	7.1	-0.7	-2.7	-0.4	-0.6	1.4	-0.8	-1.6	-1.3	-1.8	-1.9	1.2	-1.2	-0.3
Ovarian Cancer	0.4	0.5	3.6	-0.2	0.1	-0.1	-0.3	-1.4	-0.2	-0.4	0.6	0.4	1.0	1.9	-0.1	0.2
Neuroticism (2016)	0.4	0.6	4.0	0.0	-0.6	0.1	-0.1	-1.5	0.2	-1.3	0.0	-0.3	-0.2	-2.0	0.0	-0.7
Medication: Co-codamol	0.4	0.4	2.1	-1.1	-0.2	-0.3	-1.5	0.2	-0.5	-0.7	-0.4	-0.3	-0.9	-0.2	-0.3	-0.7
Current tobacco smoking	0.4	0.6	1.6	-1.0	0.5	-1.1	-1.0	0.5	-0.8	-1.2	0.3	0.4	1.1	0.7	-0.6	0.8
Serious illness, injury or assault to yourself	0.4	0.5	1.3	1.1	-0.2	0.8	1.1	1.1	0.8	0.4	0.2	0.1	-0.3	0.8	0.6	0.9
Diverticular disease/diverticulitis (self-reported)	0.4	0.4	0.9	-0.8	-0.9	-0.6	-0.8	0.4	-0.9	0.2	-0.7	-0.8	-0.5	0.3	-0.9	-0.5
Number of incorrect matches in round	0.4	0.6	5.4	-0.5	-0.5	-0.4	-0.4	-0.8	-0.4	0.2	-0.4	-0.5	-0.6	-2.3	-0.6	-0.6
Number of live births	0.4	0.5	2.9	-1.3	0.3	-0.2	-1.7	0.7	-0.2	-0.3	-0.0	0.1	0.1	1.3	-0.1	-0.6
Forced expiratory volume in 1-second (FEV1)	0.4	1.2	4.0	-1.7	-0.7	-0.5	-2.0	-0.3	-1.0	-0.3	-1.2	-1.0	-1.5	0.9	-0.8	-1.4
Illnesses of mother	0.4	0.5	1.3	-0.8	0.6	-0.9	-0.8	-1.1	-0.9	-0.8	-0.1	0.2	0.7	-0.9	-0.5	0.1
Pulse wave reflection index	0.4	0.5	1.3	0.7	0.6	0.4	0.8	0.7	0.3	0.5	0.8	0.8	1.1	0.9	0.5	0.6
Leg fat percentage (right)	0.4	1.5	6.8	-0.3	-2.6	-0.4	-0.2	0.5	-0.6	-1.7	-1.3	-1.9	-1.9	-0.5	-1.1	-0.4
Wheeze or whistling in the chest in last year	0.4	0.7	1.2	-1.1	-1.0	-0.7	-1.1	-0.7	-0.9	-1.1	-0.8	-1.0	-1.0	-0.4	-0.9	-0.3
Leg fat mass (right)	0.4	1.7	6.7	-0.6	-2.6	-0.4	-0.6	1.5	-0.8	-1.6	-1.2	-1.7	-1.9	1.2	-1.1	-0.2
Ever had bowel cancer screening	0.4	0.5	2.5	-0.4	-1.3	-0.3	-0.5	1.6	-0.3	-0.9	-0.4	-0.8	-0.3	-0.5	-0.6	-0.2
Medication for cholesterol	0.4	0.6	1.8	-0.5	-0.8	-0.9	-0.2	0.3	-0.9	-0.5	-1.4	-1.1	-1.1	-0.3	-0.9	-0.8
Smoking status: Current	0.4	0.6	2.0	-1.0	0.6	-1.1	-1.1	0.3	-0.7	-1.4	0.4	0.5	1.1	0.2	-0.5	0.7
Commuting to job workplace: Public transport	0.4	0.5	1.1	-1.0	-0.6	-0.9	-1.1	0.3	-0.8	-0.9	-0.6	-0.5	-0.3	0.5	-0.8	-0.6
High cholesterol (Self-reported)	0.4	0.7	3.0	0.2	1.1	0.8	-0.1	0.5	0.8	-0.4	1.0	1.1	0.7	0.2	0.9	1.7
Ever had prostate specific antigen (PSA) test	0.4	0.5	0.8	-0.6	-0.8	-0.7	-0.4	-0.5	-0.9	-0.7	-0.8	-0.8	-0.6	-0.6	-0.9	-0.4
Heart disease (siblings)	0.4	0.5	1.8	0.5	0.6	0.8	0.3	0.9	0.8	0.8	0.8	0.8	0.4	1.3	0.8	0.4
Ulcerative Colitis (UC)	0.3	0.6	3.0	0.9	0.8	0.4	1.2	-0.3	0.2	1.0	0.2	0.5	0.2	1.7	0.4	0.5
Bipolar Disorder (2011)	0.3	0.3	1.0	0.7	1.0	0.3	0.6	-0.1	0.8	0.8	0.7	0.8	0.6	-0.0	0.0	0.0
Smoking Status	0.3	0.6	6.4	0.3	-0.0	-0.2	0.5	1.1	-0.1	-0.6	0.1	0.1	0.3	2.5	-0.1	0.3
Number of treatments/medications taken	0.3	0.6	6.0	0.3	-0.4	0.6	0.1	0.8	0.5	0.3	0.4	0.2	0.1	2.4	0.3	0.0
Ever had hysterectomy (womb removed)	0.3	0.4	1.2	-0.8	-0.2	-0.1	-0.9	-1.1	-0.4	-0.8	0.3	0.0	0.7	-0.4	-0.3	0.8
Angina	0.3	0.4	1.5	-0.0	1.1	0.4	-0.1	-0.3	0.2	0.1	0.8	1.0	1.0	0.6	0.5	1.2
Pack years adult smoking proportion	0.3	0.5	1.7	-0.6	0.3	-1.3	-0.3	-1.3	-1.1	-1.1	-0.5	-0.1	0.0	-0.0	-0.8	-0.4
Trunk fat percentage	0.3	1.0	2.6	1.4	-0.6	1.3	1.4	1.6	1.0	0.1	0.6	0.1	-0.0	1.3	0.7	1.4
Relative age voice broke	0.3	0.5	1.4	0.8	0.5	0.0	1.1	1.0	-0.1	0.9	0.1	0.4	0.2	1.2	0.1	1.0
Taking other prescription medications	0.3	0.4	3.1	0.3	-0.7	0.4	0.3	1.2	0.2	0.7	-0.1	-0.3	-0.3	1.8	0.0	0.2
Qualifications: CSEs or equivalent	0.3	0.3	1.2	-0.8	-0.2	-0.9	-0.5	-0.3	-1.1	-0.6	-0.5	-0.4	0.1	0.0	-0.9	-0.3
Stomach or abdominal pain in last month	0.3	0.4	2.5	0.5	-0.3	0.1	0.7	1.3	-0.1	0.4	0.1	-0.0	-0.1	1.6	-0.1	0.0
Medication: Atenolol	0.3	0.3	1.8	-0.3	0.9	-0.3	-0.2	-0.3	-0.2	-0.3	0.7	0.8	1.3	0.4	0.0	0.6
High blood pressure (mother)	0.3	0.4	1.3	-0.1	-1.1	0.5	-0.3	0.9	0.3	-0.6	-0.3	-0.5	-1.1	0.3	0.0	-0.9
Trunk fat mass	0.3	1.3	6.6	0.7	-1.0	1.0	0.6	2.6	0.6	-0.1	0.3	-0.2	-0.4	2.5	0.3	1.0
Hair/balding pattern: Pattern 2	0.3	0.4	1.2	0.3	0.9	0.4	0.1	0.4	0.6	0.7	0.5	0.7	0.5	0.6	0.7	1.1
Fluid intelligence score	0.3	0.7	2.6	-1.2	-0.4	-1.1	-1.1	-1.6	-1.2	-0.3	-0.6	-0.6	-0.2	-0.2	-1.0	-0.4
Illnesses of siblings	0.3	0.4	2.8	-0.0	-0.4	-0.9	0.3	-1.7	-0.6	-0.0	-0.5	-0.5	-0.3	-0.5	-0.7	0.1
Hip circumference	0.3	1.3	6.2	-0.0	-1.7	0.4	-0.2	2.2	0.0	-1.4	-0.3	-0.8	-1.0	2.5	-0.2	0.2
Alcohol intake versus 10 years previously	0.3	0.4	3.1	-0.2	-0.2	-0.0	-0.3	1.1	-0.1	-1.1	-0.1	-0.1	-0.2	-1.8	-0.1	0.3
Father’s age at death	0.3	0.5	3.3	0.9	-0.8	0.2	1.0	1.8	0.5	-0.1	0.1	-0.3	-0.1	0.4	0.1	0.4
Pulse rate	0.3	0.5	1.9	-1.2	-0.3	-0.5	-1.4	0.4	-0.6	-0.9	-0.4	-0.4	-0.4	0.6	-0.6	-0.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	0.9	3.5	-1.4	-0.5	0.0	-1.9	-0.2	-0.5	0.1	-1.0	-0.8	-1.3	1.1	-0.4	-1.3
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	1.8	1.0	0.2	0.2	1.3	-1.4	0.1	0.8	0.2	0.3	0.1	0.4	0.2	0.6
Glaucoma (self-reported)	0.3	0.4	2.4	0.1	0.2	0.6	-0.1	1.6	0.4	0.9	0.1	0.1	-0.0	1.0	0.4	0.0
Mouth/teeth dental problems: Loose teeth	0.3	0.4	1.4	-0.7	-0.7	-0.6	-0.7	-0.2	-0.4	-0.0	-0.8	-0.8	-1.2	-0.5	-0.5	-0.5
Medication for pain relief, constipation, heartburn	0.3	0.5	4.3	-0.2	0.8	-0.4	-0.2	-1.2	-0.0	0.2	-0.1	0.3	0.1	-2.1	0.1	-0.0
Medication: Allopurinol	0.3	0.4	2.2	-0.3	0.8	-0.5	-0.2	0.4	-0.4	0.2	0.5	0.6	1.5	-0.6	-0.1	1.0
Heart disease (mother)	0.3	0.4	1.2	-0.8	-1.0	-0.0	-1.1	0.3	-0.1	-0.9	-0.5	-0.7	-0.3	-0.8	-0.4	-0.7
Whole body fat mass	0.3	1.1	4.0	-0.1	-1.8	0.1	-0.2	1.9	-0.2	-1.0	-0.6	-1.0	-1.2	2.0	-0.5	0.3
Alcohol intake frequency.	0.3	0.6	4.0	-0.2	0.5	-0.6	0.0	2.0	-0.5	0.1	0.3	0.4	0.5	1.5	-0.3	0.9
Age at last live birth	0.3	0.4	1.8	-0.6	-0.9	-0.4	-0.7	-0.0	-0.4	-0.9	-0.5	-0.7	-0.6	-0.3	-0.6	-1.4
Illnesses of father: Heart disease	0.3	0.5	2.0	-1.1	-0.4	-0.3	-1.3	-1.4	-0.5	-0.6	-0.3	-0.5	-0.1	0.2	-0.6	-0.3
Arm fat percentage (left)	0.3	1.2	5.0	-0.3	-2.2	-0.6	-0.1	0.8	-0.8	-1.9	-0.9	-1.4	-1.2	0.5	-1.1	-0.0
Average weekly champagne plus white wine intake	0.3	0.4	1.4	-0.4	-0.7	-0.6	-0.4	-0.7	-0.5	-0.4	-0.8	-0.8	-1.1	-0.1	-0.5	-1.2
Guilty feelings	0.3	0.4	1.6	-0.9	-0.2	-0.2	-1.3	1.2	-0.1	-1.1	0.1	-0.0	-0.0	0.9	-0.0	-0.2
Medication: Bendroflumethiazide	0.3	0.5	1.3	1.2	0.3	1.1	1.2	0.2	0.8	0.3	0.4	0.4	-0.2	0.1	0.9	0.5
Medication: Paracetamol	0.3	0.5	1.8	-0.4	-1.3	-0.4	-0.3	0.4	-0.4	-0.5	-0.7	-1.0	-1.0	0.3	-0.7	-0.9
Age started oral contraceptive pill	0.3	0.4	1.3	0.3	0.8	0.7	-0.0	1.1	0.9	0.7	0.6	0.6	0.7	-0.2	0.9	0.3
Unable to work because of sickness or disability	0.3	0.4	1.0	0.7	0.9	0.6	0.6	0.5	0.8	0.5	0.8	1.0	0.6	-0.6	0.9	0.0
Pack years of smoking	0.3	0.4	1.5	-0.5	0.2	-1.1	-0.1	-1.2	-1.0	-1.0	-0.5	-0.2	-0.1	-0.2	-0.8	-0.4
Schizophrenia vs Biploar Disorder	0.2	0.2	0.7	0.6	-0.4	0.4	0.8	0.2	0.3	0.6	-0.5	-0.4	-0.8	0.2	0.1	-0.2
Prostate Cancer	0.2	0.2	1.5	1.0	0.2	0.3	1.2	-0.5	0.4	-0.1	0.0	0.1	-0.5	-0.2	0.3	-0.2
Body Mass Index (BMI) (2010)	0.2	0.3	1.5	-0.8	0.0	-0.4	-1.0	0.5	-0.3	-0.3	0.1	0.2	0.3	1.2	-0.3	-0.5
LDL Cholesterol	0.2	0.3	2.3	-0.7	0.2	-0.6	-0.7	-1.5	-0.6	0.2	-0.0	0.1	0.1	0.4	-0.4	-0.2
Lupus	0.2	0.3	2.0	0.4	0.7	0.7	0.2	0.4	0.7	1.4	0.3	0.6	0.1	0.0	0.7	-0.3
Ulcerative Colitis	0.2	0.3	1.8	0.6	0.5	0.3	0.8	-0.3	0.2	0.4	0.3	0.3	0.4	1.4	0.2	0.2
Blood Platelet Count	0.2	2.3	6.2	-2.3	-0.6	-1.7	-2.5	-1.1	-1.7	-2.5	-0.9	-0.6	-0.2	1.4	-1.5	-1.0
Blood White Count	0.2	1.8	5.2	-1.3	-1.8	-1.1	-1.2	-0.0	-1.3	-2.3	-1.4	-1.7	-1.4	-0.6	-1.4	-1.4
Systolic Blood Pressure	0.2	0.8	2.6	0.8	0.8	1.6	0.6	0.6	1.3	-0.0	0.8	0.8	0.4	1.4	1.1	-0.1
Cardiovascular Disease	0.2	0.6	2.9	-0.9	-0.3	-0.5	-0.8	-1.1	-0.8	-1.7	-0.5	-0.5	-0.5	0.3	-0.7	-0.4
Respiratory disease	0.2	0.5	1.4	-1.1	-0.5	-0.7	-1.2	-0.7	-0.8	-1.1	-0.3	-0.4	-0.2	0.3	-0.8	0.2
Relative age of first facial hair	0.2	0.3	0.9	0.2	-0.4	-0.7	0.6	-1.0	-0.8	0.2	-0.5	-0.4	-0.4	0.9	-0.6	0.4
Vitamin and mineral supplements	0.2	0.3	0.9	-0.7	-0.5	-0.3	-0.9	0.1	-0.3	-0.1	-0.8	-0.6	-0.9	0.3	-0.3	0.4
Medication: Metformin	0.2	0.3	1.3	-0.1	0.0	0.1	-0.2	1.0	0.1	-0.2	0.7	0.4	0.7	1.2	0.1	-0.0
Townsend deprivation index at recruitment	0.2	0.3	2.1	-0.4	0.6	-0.2	-0.6	1.5	0.2	-0.3	0.5	0.7	0.6	-0.2	0.2	0.6
Medication: Levothyroxine sodium	0.2	0.3	0.9	-0.6	-1.0	-0.5	-0.6	-0.1	-0.6	-0.8	-0.6	-0.8	-0.6	-0.3	-0.7	-0.3
Financial difficulties in last 2 years	0.2	0.3	1.1	0.1	-0.6	-0.4	0.3	0.8	-0.4	0.3	-0.9	-0.7	-1.0	0.0	-0.4	-0.5
Medication: Simvastatin	0.2	0.3	1.1	0.1	0.7	0.4	-0.1	0.2	0.5	0.7	0.7	0.7	0.7	0.4	0.5	1.0
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	1.4	-0.5	-1.1	-0.2	-0.7	0.4	-0.2	-0.7	-0.2	-0.5	-0.5	0.5	-0.4	-1.2
Noisy workplace	0.2	0.2	0.9	0.4	-0.4	-0.3	0.7	-0.2	-0.3	-0.2	-0.3	-0.4	-0.6	-0.3	-0.3	-0.9
Depression (self-reported)	0.2	0.2	1.1	-0.3	-0.4	-0.4	-0.4	-0.0	-0.0	0.2	-0.4	-0.4	-0.4	-0.9	-0.3	-1.0
Prospective memory result	0.2	0.3	1.0	-0.3	-0.4	-0.8	0.1	-0.2	-1.0	-0.6	-0.5	-0.4	0.1	0.3	-0.9	0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	0.8	0.4	-0.9	-0.2	0.7	0.3	-0.1	0.5	-0.7	-0.8	-0.8	-0.5	-0.4	-0.5
Loud music exposure frequency	0.2	0.2	1.5	-0.1	0.3	-0.6	0.1	-0.4	-0.4	0.9	-0.2	0.0	-0.1	1.2	-0.3	-0.1
Medication: Paracetamol	0.2	0.3	1.1	-0.3	-1.0	-0.2	-0.3	0.7	-0.3	-0.6	-0.4	-0.7	-0.6	0.8	-0.5	-0.5
Headache pain in last month	0.2	0.3	1.3	0.0	0.9	-0.5	0.3	-0.4	-0.4	0.1	0.6	0.7	1.2	0.8	-0.2	0.6
Chronic bronchitis/emphysema (mother)	0.2	0.2	0.9	0.2	0.4	0.4	0.1	0.2	0.6	0.5	0.5	0.5	0.3	1.0	0.5	0.8
Number of children fathered	0.2	0.2	1.0	-0.0	-0.8	0.0	-0.1	0.8	0.0	-1.0	-0.1	-0.3	-0.4	-0.7	-0.2	-0.4
Shortness of breath walking on level ground	0.2	0.2	0.7	0.4	-0.7	-0.5	0.7	0.4	-0.3	-0.0	-0.6	-0.6	-0.8	0.1	-0.4	0.0
Neck or shoulder pain in last month	0.2	0.2	1.1	-0.0	-0.6	-0.3	0.1	0.9	-0.2	0.2	-0.5	-0.5	-0.6	0.1	-0.3	-1.0
Medication: Blood pressure	0.2	0.3	0.8	0.7	-0.1	0.9	0.6	0.8	0.7	-0.5	0.0	0.0	-0.3	0.8	0.5	0.6
Angina (self-reported)	0.2	0.3	1.0	-0.3	0.8	0.2	-0.4	-0.5	-0.1	-0.1	0.5	0.7	0.7	0.4	0.2	1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.2	1.0	0.4	0.3	-0.3	0.6	0.2	-0.0	0.1	0.5	0.4	1.0	0.7	0.0	-0.0
Illness, injury, bereavement, stress in last 2 years	0.2	0.3	2.2	-0.4	0.2	-0.2	-0.4	-0.5	-0.2	-0.6	-0.1	-0.0	0.2	-1.5	-0.2	-0.6
Loneliness, isolation	0.2	0.3	1.6	0.6	-1.3	0.1	0.8	-0.4	0.1	-0.7	-0.3	-0.7	-0.7	0.1	-0.2	-0.1
Eye problems/disorders: Cataract	0.2	0.2	1.5	-0.8	0.2	0.2	-1.2	-0.4	-0.1	0.0	0.1	0.3	0.1	0.6	0.1	-0.2
Supplements: Fish oil (including cod liver oil)	0.2	0.2	0.8	-0.5	0.5	0.2	-0.8	-0.3	0.3	-0.1	0.5	0.4	0.4	-0.9	0.3	-0.5
Medication: Lisinopril	0.2	0.3	1.0	0.2	0.6	0.7	0.1	-0.2	0.6	-0.4	0.6	0.6	0.3	0.8	0.6	1.0
Diastolic blood pressure, automated reading	0.2	0.7	2.2	-0.4	-1.0	0.5	-0.8	1.2	0.4	-1.3	-0.7	-0.8	-1.5	0.3	0.1	-1.2
Pain experienced in last month	0.2	0.3	0.7	0.1	0.7	0.7	-0.2	-0.4	0.7	-0.2	0.7	0.7	0.6	-0.9	0.7	0.6
Alcohol drinker status: Previous	0.2	0.3	1.8	1.0	-0.1	0.0	1.4	-0.5	0.1	-0.2	0.1	-0.0	-0.4	-0.5	0.0	0.5
Intelligence (Savage-Jansen 2018)	0.1	0.2	0.6	-0.6	0.4	-0.3	-0.7	-0.8	-0.4	0.2	0.1	0.2	0.4	0.0	-0.1	0.8
Alzheimer’s Disease (including proxy)	0.1	0.1	0.5	-0.1	0.2	0.0	-0.1	0.3	-0.1	0.2	0.3	0.1	0.7	-0.0	-0.1	0.7
Crohns Disease (2017)	0.1	0.2	1.1	0.9	-0.1	0.3	1.1	-0.5	0.2	0.7	0.3	0.3	0.3	0.2	0.2	0.5
Irritable Bowel Disease (IBD)	0.1	0.3	1.3	0.8	0.4	0.2	1.1	-0.5	-0.0	0.8	0.2	0.4	0.4	1.0	0.2	0.5
Crohns Disease (2012)	0.1	0.2	0.7	0.3	-0.6	-0.2	0.5	-0.8	-0.2	0.0	-0.0	-0.2	0.1	-0.8	-0.2	-0.6
HbA1C	0.1	0.1	0.3	0.5	-0.1	0.4	0.5	0.4	0.4	-0.2	-0.1	0.0	-0.5	-0.1	0.1	-0.1
Primary Biliary Cirrhosis	0.1	0.1	0.6	-0.1	0.6	-0.8	0.1	-0.2	-0.4	-0.1	-0.2	0.3	0.4	0.0	-0.3	0.1
Hypothyroidism (self reported)	0.1	0.1	0.8	-0.3	0.0	-0.2	-0.3	0.9	-0.4	0.1	0.2	0.1	0.5	0.5	-0.3	0.2
Type 2 Diabetes (T2D) (2018)	0.1	0.1	0.3	0.5	-0.5	0.1	0.6	-0.3	0.2	-0.4	0.3	0.1	0.2	0.5	0.1	-0.1
Tanning	0.1	0.6	1.8	0.8	1.0	0.6	0.9	0.5	0.4	0.6	0.6	0.9	0.7	1.2	0.7	1.3
Diabetes (mother)	0.1	0.2	1.6	-0.1	-0.2	0.4	-0.3	1.2	0.4	-0.1	0.2	0.1	0.1	0.1	0.2	-0.4
High blood pressure	0.1	0.2	0.6	-0.4	-0.6	0.2	-0.5	0.5	-0.1	-0.8	-0.5	-0.6	-0.8	-0.1	-0.2	-0.5
Multivitamins +/- minerals	0.1	0.2	0.8	0.4	0.2	-0.2	0.7	-0.9	-0.1	0.5	0.5	0.2	0.6	-0.3	-0.1	-0.3
Alcohol usually taken with meals	0.1	0.1	0.4	0.3	0.4	0.0	0.3	-0.0	0.2	0.0	0.3	0.3	0.0	-0.6	0.2	0.7
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.2	1.1	-0.8	-0.1	-0.0	-1.1	-0.7	-0.1	-0.3	0.0	-0.1	-0.1	-0.6	-0.1	-0.2
Qualifications: None of the above	0.1	0.2	0.9	0.3	0.6	0.6	0.2	0.9	0.7	0.3	0.4	0.5	0.3	-0.6	0.5	0.1
Pain all over the body in last month	0.1	0.1	0.7	0.4	0.3	0.1	0.6	-0.4	-0.1	-0.3	-0.1	0.2	0.0	0.9	0.1	0.0
Diabetes (self-reported)	0.1	0.1	0.4	-0.2	-0.6	0.1	-0.4	0.5	-0.0	-0.6	0.1	-0.1	-0.1	0.5	-0.1	-0.3
Hayfever/allergic rhinitis (self-reported)	0.1	0.2	0.8	0.3	-0.0	0.7	0.0	0.9	0.7	0.2	0.6	0.3	0.1	0.2	0.6	-0.2
Happiness	0.1	0.1	0.3	-0.1	-0.3	-0.2	-0.1	0.1	-0.2	-0.5	-0.4	-0.2	-0.1	0.4	-0.2	-0.3
Asthma	0.1	0.1	0.5	0.4	-0.4	0.5	0.3	0.2	0.4	-0.2	0.4	0.1	-0.0	0.4	0.3	0.7
Exposure to tobacco smoke at home	0.1	0.1	0.4	-0.1	0.0	0.6	-0.5	0.6	0.6	0.2	0.2	0.3	-0.2	0.1	0.4	0.0
Peak expiratory flow (PEF)	0.1	0.3	1.1	-0.5	-0.4	0.2	-0.6	-0.2	-0.3	0.6	-0.4	-0.5	-0.5	1.0	-0.2	-0.8
Hypothyroidism/myxoedema (self-reported)	0.1	0.1	0.7	-0.1	-0.4	-0.3	-0.0	0.8	-0.4	0.0	-0.1	-0.2	-0.1	0.3	-0.4	-0.1
High blood pressure (siblings)	0.1	0.2	0.8	-0.1	-0.3	0.5	-0.3	0.9	0.3	-0.5	-0.2	-0.2	-0.7	-0.2	0.2	-0.5
Body fat percentage	0.1	0.5	2.2	0.6	-1.5	0.4	0.7	1.2	0.2	-0.7	-0.3	-0.8	-0.8	0.6	-0.2	0.7
Pulse rate, automated reading	0.1	0.4	1.2	-0.3	0.4	0.9	-0.9	1.1	0.9	-0.4	0.4	0.6	0.0	0.6	0.8	0.5
Overall health rating	0.1	0.2	2.4	0.2	-0.3	-0.0	0.3	0.5	-0.1	-0.7	0.1	0.0	-0.2	1.6	-0.0	-0.3
Hypertension (Self-reported)	0.1	0.2	0.7	-0.2	-0.3	0.2	-0.2	0.8	-0.0	-0.7	-0.4	-0.4	-0.7	-0.0	-0.2	-0.5
Illnesses of siblings: Diabetes	0.1	0.2	1.3	0.3	-0.2	0.0	0.4	0.8	0.0	0.0	-0.1	-0.1	0.0	-0.5	-0.1	-1.2
Diabetes diagnosed by doctor	0.1	0.1	0.5	-0.1	-0.7	-0.1	-0.0	-0.0	-0.2	-0.6	0.0	-0.2	-0.0	0.7	-0.3	-0.5
Commuting to job workplace: Walk	0.1	0.1	0.4	-0.3	-0.0	0.1	-0.5	0.4	0.1	-0.6	0.0	0.0	-0.1	0.4	0.0	-0.5
Illnesses of father: None of the above (group 1)	0.1	0.1	0.4	0.1	-0.2	-0.6	0.4	-0.4	-0.6	-0.1	-0.3	-0.2	-0.3	0.0	-0.4	0.1
Tinnitus: Yes, now most or all of the time	0.1	0.1	0.3	-0.4	0.2	-0.0	-0.6	-0.1	-0.0	0.1	0.1	0.1	0.3	-0.5	-0.0	0.0
Medication: Blood pressure	0.1	0.1	0.3	0.5	-0.1	0.5	0.5	-0.3	0.4	-0.2	0.4	0.1	0.2	-0.6	0.3	-0.2
Average weekly beer plus cider intake	0.1	0.1	0.3	-0.2	0.2	-0.6	-0.0	0.0	-0.5	-0.5	-0.3	-0.1	0.2	-0.5	-0.4	0.2
Irritability	0.1	0.2	1.3	0.2	0.4	0.2	0.1	0.2	0.3	-0.3	0.8	0.6	0.8	-1.1	0.3	-0.3
Myopia	0.1	0.1	0.7	-0.6	0.0	-0.0	-0.8	-0.7	-0.0	-0.2	0.1	-0.0	0.1	-0.6	-0.1	0.2
Blood Eosinophil Count	0.0	0.4	1.2	-0.4	-0.5	-0.7	-0.2	-0.3	-1.1	-1.1	-0.4	-0.4	-0.1	-0.7	-0.9	-0.1
Hair Pigment	0.0	0.8	3.3	1.0	0.8	1.1	0.9	0.5	0.8	-0.2	1.0	0.9	0.7	-0.4	1.1	1.8
Qualifications: A levels/AS levels or equivalent	0.0	0.1	0.3	-0.4	0.2	-0.3	-0.6	0.4	-0.1	-0.1	0.3	0.2	0.5	0.3	0.1	-0.3
Medication: Seretide 50 evohaler	0.0	0.0	0.1	0.1	-0.0	-0.0	0.1	0.3	0.2	-0.0	0.2	0.2	0.2	0.1	0.1	0.1
Asthma (self-reported)	0.0	0.1	0.4	0.2	-0.3	0.4	0.1	0.2	0.3	-0.3	0.3	0.0	-0.1	0.2	0.2	0.6
Vascular/heart problems diagnosed by doctor	0.0	0.1	0.3	-0.1	0.1	-0.6	-0.0	-0.4	-0.2	0.5	-0.1	0.0	0.1	-0.4	-0.1	-0.3

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