TWAS hub - ATG9B

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Ovarian Serous Cystadenocarcinoma	0.082	0.048	0.0074	0.033	0.001	0.023	NA	0.033	2.7e-03	0.25000	1.0e-02	NA	2.5e-03
2	TCGA	Thyroid Carcinoma	0.045	0.023	0.0033	0.044	0.030	0.045	NA	0.039	3.5e-05	0.00058	2.9e-05	NA	9.9e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Allergy or Eczema	5.4	14.3	18.0	-4.2	-3.3
Back pain experienced in last month	5.3	7.8	12.6	-3.5	-1.7
Fractured/broken bones in last 5 years	5.2	6.7	8.8	3.0	2.1
Mean Putamen Volume	5.1	5.8	8.9	3.0	1.6
Seen a psychiatrist for nerves, anxiety, tension or depression	5.0	6.4	9.1	1.9	3.0
Hayfever, allergic rhinitis or eczema	4.9	10.6	14.3	-3.8	-2.7
Comparative height size at age 10	4.7	26.0	42.4	-6.5	-3.1
Medication for cholesterol, blood pressure or diabetes	4.5	7.4	14.8	-3.9	0.0
Cardiovascular Disease	4.4	14.5	28.8	5.4	0.3
Maternal smoking around birth	4.4	6.4	8.1	2.1	2.9
Chronic bronchitis/emphysema (father)	4.0	4.6	8.3	-2.9	-1.0
Eye problems/disorders: Diabetes related eye disease	3.8	4.2	5.0	-1.8	-2.2
Medication for hormone replacement therapy	3.7	4.1	5.4	-1.7	-2.3
Vascular/heart problems diagnosed by doctor	3.6	9.7	19.3	-4.4	-0.3
Trunk fat-free mass	3.5	19.9	39.4	-6.3	0.6
Trunk predicted mass	3.5	20.2	39.9	-6.3	0.7
Birth weight of first child	3.5	6.4	10.6	-3.3	1.5
Medication: Atorvastatin	3.4	4.2	7.0	2.7	1.1
Depressed Affect (Nagel 2018)	3.2	6.6	11.8	1.2	3.4
Medication: Cholesterol lowering	3.2	4.9	9.8	3.1	-0.2
Eye problems/disorders: None of the above	3.2	3.7	5.2	2.3	1.5
Whole body water mass	3.2	18.1	36.1	-6.0	0.4
Arm fat-free mass (left)	3.1	16.0	30.7	-5.5	1.1
Arm predicted mass (left)	3.1	15.5	30.0	-5.5	1.0
Tinnitus: Yes, but not now, but have in the past	3.0	3.2	5.6	0.8	2.4
Serious illness, injury or assault of a close relative in last 2 years	3.0	3.4	6.6	-0.6	-2.6
Medication: Blood pressure	3.0	5.3	10.7	3.3	-0.1
Whole body fat-free mass	3.0	17.0	33.9	-5.8	0.4
Hearing difficulty/problems: Yes	2.9	4.4	6.9	-1.4	-2.6
Sitting height	2.9	20.9	30.0	-5.5	-3.4
Arm fat-free mass (right)	2.9	14.8	29.5	-5.4	0.2
Migraine (self-reported)	2.9	3.6	3.6	1.9	-1.9
Arm predicted mass (right)	2.9	14.9	29.5	-5.4	0.5
Basal cell carcinoma (self-reported)	2.9	3.5	5.1	-2.2	-1.4
Ever had stillbirth, spontaneous miscarriage or termination	2.8	3.0	6.0	-0.3	-2.4
Osteoarthritis (self-reported)	2.8	3.7	7.2	-0.3	-2.7
Lung FVC	2.7	13.6	26.9	-0.5	5.2
Ever unenthusiastic/disinterested for a whole week	2.7	3.2	5.3	2.3	1.1
Impedance of arm (left)	2.7	12.6	15.9	4.0	-3.1
Hypertension (Self-reported)	2.7	7.4	14.2	3.8	0.7
Impedance of whole body	2.7	13.7	19.6	4.4	-2.8
Height	2.6	50.9	87.8	-9.4	-3.7
Impedance of leg (right)	2.6	12.6	22.5	4.7	-1.6
High blood pressure	2.6	7.3	13.8	3.7	0.9
Basal metabolic rate	2.6	14.4	28.5	-5.3	0.6
Number of operations (self-reported)	2.6	3.8	7.1	-2.7	-0.7
Heel bone mineral density (BMD) T-score, automated (left)	2.5	5.6	6.7	-2.1	-2.6
Impedance of leg (left)	2.5	11.9	21.2	4.6	-1.6
Allergy	2.5	5.8	7.2	2.7	2.1
Medication: Aspirin	2.5	3.4	5.7	2.4	-1.0
Diabetes (mother)	2.4	3.1	5.7	-2.4	-0.7
Diastolic blood pressure, automated reading	2.4	7.4	14.5	3.8	0.6
Supplements: Glucosamine	2.3	2.9	3.9	-1.4	-2.0
Hearing difficulty/problems with background noise	2.3	3.7	3.9	-2.0	-1.9
Ever highly irritable/argumentative for 2 days	2.3	2.7	3.3	1.8	1.5
Leg fat-free mass (right)	2.3	12.3	24.5	-5.0	0.3
Leg predicted mass (right)	2.2	12.0	23.8	-4.9	0.3
Miserableness	2.2	3.8	4.6	1.7	2.1
Heel bone mineral density (BMD) T-score, automated (right)	2.1	4.8	4.8	-2.2	-2.2
Impedance of arm (right)	2.1	10.0	13.9	3.7	-2.5
Health satisfaction	2.1	2.7	4.5	2.1	-0.9
Medication: Aspirin	2.1	2.7	5.2	2.3	-0.5
Leg fat-free mass (left)	2.0	10.7	21.3	-4.6	0.1
Fed-up feelings	2.0	3.6	5.2	1.4	2.3
Leg predicted mass (left)	2.0	10.5	21.0	-4.6	0.2
Standing height	2.0	20.2	31.8	-5.6	-2.9
Medication: Ibuprofen	2.0	2.3	4.4	-2.1	0.5
Qualifications: nursing, teaching	2.0	3.1	5.9	0.6	2.4
Supplements: Calcium	2.0	2.2	3.2	-1.8	1.1
Depression (Nagel 2018)	1.9	2.8	3.8	1.4	2.0
Eye problems/disorders: Glaucoma	1.9	2.3	4.2	-2.0	-0.6
Hand grip strength (left)	1.8	4.7	7.8	1.2	2.8
Medication: Amlodipine	1.8	2.5	3.1	1.4	1.8
Schizophrenia (2014)	1.7	3.7	3.9	-1.9	-2.0
Mouth/teeth dental problems	1.7	2.6	3.8	1.1	2.0
Pulse wave Arterial Stiffness index	1.7	2.0	2.3	-1.3	-1.5
Neuroticism (Nagel 2018)	1.6	3.7	6.4	1.0	2.5
Systolic Blood Pressure	1.6	7.9	14.7	3.8	-1.1
Chronotype (morning person)	1.6	3.8	4.1	-2.0	1.8
Frequency of depressed mood in last 2 weeks	1.6	2.2	3.8	0.8	2.0
Hair/balding pattern: Pattern 3	1.6	2.3	2.6	-1.4	1.6
Qualifications: None of the above	1.5	3.2	6.2	-2.5	-0.5
Mineral and other dietary supplements	1.5	2.0	2.4	1.5	1.2
Ever depressed for a whole week	1.5	1.8	3.0	1.7	-0.8
Ulcerative Colitis	1.4	2.0	4.0	-2.0	-0.1
Heel T-Score	1.4	11.0	13.9	-2.8	-3.7
Diabetes (father)	1.4	1.7	2.9	-0.8	1.7
Bilateral oophorectomy (both ovaries removed)	1.4	1.7	3.3	0.1	-1.8
Hayfever/allergic rhinitis (self-reported)	1.4	1.9	2.1	-1.3	-1.5
Weight	1.4	7.1	13.5	-3.7	0.8
Number of full brothers	1.4	1.7	3.0	-1.7	-0.7
Mean time to correctly identify matches	1.4	2.7	5.4	-0.2	-2.3
Family relationship satisfaction	1.4	1.7	1.8	1.3	1.4
Pain type(s) experienced in last month: Hip pain	1.4	1.7	2.9	-1.7	-0.7
Reaction Time	1.3	2.6	4.9	0.5	-2.2
Medication: Atenolol	1.3	1.6	1.8	1.3	-1.2
Had other major operations	1.3	1.6	2.8	-0.6	1.7
Angina (self-reported)	1.3	1.7	2.8	1.7	-0.8
Had major operations	1.3	1.5	2.9	-1.7	-0.4
Osteoporosis (self-reported)	1.3	1.7	3.3	-0.2	1.8
Smoking status: Current	1.3	2.1	2.8	-1.2	-1.7
Bipolar Disorder or Schizophrenia	1.2	2.9	3.8	-1.4	-2.0
Ovarian Cancer	1.2	1.6	2.8	1.7	-0.7
Body Mass Index (BMI) (2010)	1.2	1.7	2.3	-1.5	-1.0
HDL Cholesterol	1.2	2.0	3.9	2.0	0.3
Primary Biliary Cirrhosis	1.2	1.7	2.6	-1.6	-0.9
Rheumatoid Arthritis	1.2	1.7	3.2	-0.4	1.8
Neuroticism	1.2	3.0	5.4	0.7	2.3
Angina	1.2	1.6	1.8	1.3	-1.2
Current tobacco smoking	1.2	1.9	2.5	-1.1	-1.6
Multivitamins +/- minerals	1.2	1.5	2.8	-1.7	-0.5
Shortness of breath walking on level ground	1.2	1.5	1.5	1.2	1.2
Qualifications: NVQ or HND or HNC or equivalent	1.2	1.4	1.8	-1.0	-1.4
Forced expiratory volume in 1-second (FEV1), predicted	1.2	2.5	3.6	-1.9	-1.2
High cholesterol (Self-reported)	1.2	2.1	2.4	1.6	-1.3
Ever smoked	1.2	2.1	3.1	-1.8	-1.0
Schizophrenia (2018)	1.1	2.2	3.2	-1.1	-1.8
Smoking Status	1.1	2.7	3.6	-1.9	-1.3
Diverticular disease/diverticulitis (self-reported)	1.1	1.3	1.9	1.4	0.8
Forced vital capacity (FVC)	1.1	4.1	6.5	-2.6	1.3
Mouth/teeth dental problems: Dentures	1.1	1.8	2.4	-1.1	-1.5
Lung cancer (father)	1.1	1.3	1.8	0.9	-1.4
Pulse wave reflection index	1.1	1.3	2.2	-1.5	-0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.1	2.3	3.7	-0.9	1.9
Medication: Blood pressure	1.1	2.1	4.1	2.0	0.1
Medication: Bendroflumethiazide	1.1	1.7	3.4	1.9	-0.2
Vitamin and mineral supplements	1.0	1.4	2.4	1.6	0.6
Breastfed as a baby	1.0	1.3	1.8	-1.3	-0.9
Forced vital capacity (FVC), Best measure	1.0	3.6	3.7	-1.9	1.9
Leg pain on walking	1.0	1.2	1.5	-1.2	-0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.0	1.2	2.1	-0.5	-1.4
Commuting to job workplace: Cycle	1.0	1.2	1.8	0.8	1.3
Prostate Cancer	0.9	1.3	1.7	-1.3	-1.0
Age at First Birth	0.9	1.3	2.2	0.7	-1.5
Supplements: Zinc	0.9	1.0	1.2	-0.9	-1.1
Time employed in main current job	0.9	1.0	1.8	0.5	-1.3
Qualifications: College or University degree	0.9	2.9	5.4	2.3	0.6
Knee pain experienced in last month	0.9	1.3	2.6	-0.3	-1.6
Illnesses of siblings: Diabetes	0.9	1.1	2.2	-1.5	-0.2
Medication for cholesterol	0.9	1.4	2.2	-0.8	1.5
Risk taking	0.9	1.3	2.5	0.3	1.6
Age started oral contraceptive pill	0.9	1.2	2.3	-1.5	-0.3
Heart attack/myocardial infarction (self-reported)	0.9	1.2	1.4	1.0	-1.2
Crohns Disease (2012)	0.8	1.2	2.5	1.6	-0.0
Blood Red Count	0.8	7.7	14.8	0.8	3.9
Medication: Metformin	0.8	1.1	1.2	-1.1	-1.1
Body mass index (BMI)	0.8	3.5	5.1	-1.4	2.2
Heart attack	0.8	1.1	1.3	0.9	-1.1
Medication: Ramipril	0.8	1.0	1.6	1.3	0.7
Medication: Simvastatin	0.8	1.2	1.7	1.3	-0.8
Arm fat mass (right)	0.8	3.1	3.6	-1.9	1.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.2	1.3	1.1	1.0
Pulse wave peak to peak time	0.8	0.9	1.2	0.8	1.1
Alcohol intake frequency.	0.8	1.8	3.5	-1.9	-0.4
Commuting to job workplace: Car/motor vehicle	0.8	0.9	1.8	-0.1	1.3
Commuting to job workplace: Walk	0.8	0.9	1.5	1.2	-0.5
Hearing aid user	0.8	0.9	1.5	-1.2	0.6
Ulcerative Colitis (UC)	0.7	1.3	2.1	-1.4	-0.7
Breast Cancer	0.7	1.7	2.5	1.6	1.0
Waist Hip Ratio (WHR)	0.7	3.2	3.5	1.7	1.9
Waist circumference	0.7	2.4	3.6	-1.1	1.9
Past tobacco smoking	0.7	1.2	1.4	1.0	1.2
Father’s age at death	0.7	0.9	1.4	-1.2	0.6
Forced expiratory volume in 1-second (FEV1)	0.7	2.5	3.6	-1.9	1.2
Glaucoma (self-reported)	0.7	0.8	1.3	-1.1	0.6
Birth weight	0.7	1.4	2.8	-1.7	-0.1
Leg fat percentage (right)	0.7	2.6	3.3	1.4	1.8
Number of children fathered	0.7	0.8	0.9	-1.0	0.8
Pulse rate, automated reading	0.7	2.3	3.3	1.2	-1.8
Mood swings	0.7	1.3	2.5	0.1	1.6
Ever had bowel cancer screening	0.7	0.9	1.3	-0.6	1.1
Leg fat percentage (left)	0.7	2.6	3.8	1.2	1.9
Irritability	0.7	1.1	1.8	-0.6	-1.4
Cholesterol lowering medication	0.7	1.1	2.2	1.5	-0.0
HbA1C	0.6	0.6	1.3	1.1	-0.0
Average weekly spirits intake	0.6	0.7	1.4	-0.3	-1.2
Sensitivity / hurt feelings	0.6	1.0	2.0	0.3	1.4
Severe depression (siblings)	0.6	0.6	1.0	-1.0	-0.5
Townsend deprivation index at recruitment	0.6	0.8	1.6	-0.3	-1.3
Hip circumference	0.6	2.5	4.6	-2.1	0.6
Falls in the last year	0.6	0.8	1.0	1.0	-0.7
Depression (self-reported)	0.6	0.7	1.4	-1.2	0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	1.9	2.8	-1.7	1.0
Emphysema/chronic bronchitis	0.6	0.7	1.4	0.1	1.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.7	0.8	0.9	-0.8
Illness, injury, bereavement, stress in last 2 years	0.6	0.7	1.2	-1.1	-0.5
Arm fat mass (left)	0.6	2.6	3.3	-1.8	1.3
Wears glasses or contact lenses	0.6	0.7	1.3	-1.1	-0.2
Medication: Paracetamol	0.6	0.9	1.5	-1.2	0.6
Bipolar Disorder (2018)	0.5	0.8	0.8	-0.9	-0.9
Triglycerides	0.5	0.8	1.4	-1.2	-0.4
BMI	0.5	3.1	3.1	-1.8	1.8
Lung FEV1/FVC ratio	0.5	2.8	5.4	-0.4	-2.3
Other serious medical condition/disability diagnosed by doctor	0.5	0.6	1.2	-1.1	0.2
Ever had hysterectomy (womb removed)	0.5	0.6	1.0	1.0	-0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.7	0.8	0.8	0.9
Neuroticism score	0.5	1.0	1.8	-0.3	1.4
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	1.5	-1.2	0.0
Length of working week for main job	0.5	0.6	1.1	-0.1	1.1
Medication: Paracetamol	0.5	0.8	1.5	-1.2	0.3
Worry too long after embarrassment	0.5	0.9	1.6	-0.4	1.3
Heart disease (mother)	0.5	0.6	1.2	-0.2	1.1
Average weekly red wine intake	0.5	0.8	1.0	1.0	-0.8
Loneliness, isolation	0.5	0.7	1.5	-0.0	1.2
Mouth/teeth dental problems: Mouth ulcers	0.5	0.7	1.3	-0.4	1.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	0.8	-0.9	-0.7
Medication: Gliclazide	0.5	0.5	0.7	0.6	0.8
Illnesses of father: None of the above (group 1)	0.5	0.6	1.1	1.0	-0.3
Number of self-reported non-cancer illnesses	0.5	0.9	1.2	1.1	-0.8
Medication: Lisinopril	0.5	0.6	0.9	0.9	-0.6
Illnesses of father: High blood pressure	0.5	0.6	0.8	-0.9	-0.6
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	0.8	-0.6	-0.9
Pack years of smoking	0.5	0.7	1.2	-1.1	-0.4
LDL Cholesterol	0.4	0.6	1.2	-0.2	-1.1
Lupus	0.4	0.6	1.1	-1.1	-0.2
Ever used hormone-replacement therapy (HRT)	0.4	0.5	0.7	-0.6	-0.8
Pack years adult smoking proportion	0.4	0.7	0.7	-0.8	-0.8
Taking other prescription medications	0.4	0.6	1.1	-1.1	0.2
Financial difficulties in last 2 years	0.4	0.6	0.7	0.8	0.7
Qualifications: A levels/AS levels or equivalent	0.4	0.8	1.5	1.2	0.3
Medication: Lansoprazole	0.4	0.5	0.8	-0.9	-0.4
Illnesses of mother	0.4	0.4	0.8	-0.9	0.3
Hair/balding pattern: Pattern 4	0.4	0.9	1.8	-0.1	-1.3
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	0.6	0.8	-0.6
Gout (self-reported)	0.4	0.5	0.9	1.0	-0.3
Medication: Seretide 50 evohaler	0.4	0.4	0.5	-0.5	-0.7
Whole body fat mass	0.4	1.8	3.0	-1.7	0.8
Chest pain or discomfort	0.4	0.5	0.8	0.5	-0.9
Friendships satisfaction	0.4	0.5	1.0	-0.0	-1.0
Eye problems/disorders: Cataract	0.4	0.5	0.6	-0.8	-0.7
Supplements: Fish oil (including cod liver oil)	0.4	0.6	1.0	-1.0	-0.4
Ever had prostate specific antigen (PSA) test	0.4	0.5	0.8	0.4	0.9
Unable to work because of sickness or disability	0.4	0.5	0.8	-0.4	-0.9
Pain experienced in last month	0.4	0.6	1.3	1.1	0.1
Leg fat mass (left)	0.4	1.6	2.4	-0.9	1.5
Worry (Nagel 2018)	0.3	0.6	0.9	0.5	0.9
Alzheimer’s Disease (in father)	0.3	0.3	0.3	0.6	0.6
Crohns Disease (2017)	0.3	0.6	0.7	0.7	-0.8
Verbal and Numeric Reasoning (VNR)	0.3	0.8	1.5	0.3	1.2
Fasting Glucose	0.3	0.4	0.4	-0.6	-0.7
Blood White Count	0.3	1.9	2.8	1.7	1.0
Age when periods started (menarche)	0.3	0.8	0.8	0.9	-0.9
Medication: Levothyroxine sodium	0.3	0.5	0.5	-0.7	0.7
Trunk fat mass	0.3	1.4	2.8	-1.7	0.2
Number of incorrect matches in round	0.3	0.5	0.7	-0.9	0.5
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.4	0.8	-0.9	-0.3
Illnesses of siblings	0.3	0.4	0.6	0.5	0.7
Arm fat percentage (right)	0.3	1.3	2.6	-0.1	1.6
Worrier / anxious feelings	0.3	0.6	0.9	-0.6	1.0
Number of live births	0.3	0.4	0.7	-0.8	0.2
Pulse rate	0.3	0.5	1.0	0.2	-1.0
Happiness	0.3	0.4	0.8	0.9	-0.2
Prospective memory result	0.3	0.4	0.7	0.3	0.9
Exposure to tobacco smoke at home	0.3	0.4	0.6	0.8	-0.4
Blood clot in the leg (DVT)	0.3	0.4	0.5	-0.6	-0.7
Headache pain in last month	0.3	0.4	0.7	0.4	-0.9
Chronic bronchitis/emphysema (mother)	0.3	0.4	0.6	0.5	-0.7
High blood pressure (siblings)	0.3	0.5	0.8	0.9	-0.3
Comparative body size at age 10	0.3	0.9	1.2	-1.1	0.7
Age at first live birth	0.3	0.5	0.6	0.7	0.8
Neck or shoulder pain in last month	0.3	0.4	0.8	-0.9	-0.3
Medication: Allopurinol	0.3	0.5	0.5	0.6	-0.7
Medication: Omeprazole	0.3	0.4	0.7	-0.2	-0.8
Leg fat mass (right)	0.3	1.3	2.1	-0.6	1.4
Number of full sisters	0.3	0.4	0.6	-0.8	-0.5
Overall health rating	0.3	0.7	1.3	-0.4	-1.1
Illnesses of father: Heart disease	0.3	0.4	0.6	0.7	0.4
Long-standing illness, disability or infirmity	0.3	0.4	0.5	-0.6	-0.7
Diabetes diagnosed by doctor	0.3	0.5	0.7	-0.6	-0.8
Breast cancer (self-reported)	0.3	0.3	0.4	-0.4	0.7
Mother’s age at death	0.3	0.4	0.7	0.1	-0.8
Financial situation satisfaction	0.3	0.4	0.5	0.5	-0.7
Tinnitus: Yes, now most or all of the time	0.3	0.4	0.7	-0.9	0.0
Commuting to job workplace: Public transport	0.3	0.4	0.5	-0.7	-0.6
Irritable Bowel Disease (IBD)	0.2	0.5	0.8	-0.5	-0.9
Neuroticism (2016)	0.2	0.3	0.6	0.8	-0.2
Blood Platelet Count	0.2	1.9	3.3	-1.8	-0.7
Hypothyroidism (self reported)	0.2	0.4	0.7	-0.8	-0.3
Number of treatments/medications taken	0.2	0.4	0.7	-0.3	-0.8
Systolic blood pressure, automated reading	0.2	0.6	1.2	1.1	0.2
Medication: Co-codamol	0.2	0.2	0.3	0.5	-0.5
Hand grip strength (right)	0.2	0.6	1.0	0.5	1.0
Average weekly fortified wine intake	0.2	0.2	0.3	-0.4	-0.5
High blood pressure (mother)	0.2	0.3	0.6	0.8	0.0
Diabetes (self-reported)	0.2	0.3	0.4	-0.3	-0.7
Alcohol intake versus 10 years previously	0.2	0.3	0.5	-0.7	0.4
Peak expiratory flow (PEF)	0.2	0.5	0.6	0.6	0.8
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	0.5	0.7	-0.3
Medication: Ventolin 100micrograms inhaler	0.2	0.2	0.2	0.5	0.5
Wheeze or whistling in the chest in last year	0.2	0.3	0.4	-0.6	0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.3	0.5	0.7	0.2
Medication for pain relief, constipation, heartburn	0.2	0.3	0.4	-0.6	-0.4
Smoking status: Previous	0.2	0.2	0.3	-0.4	-0.6
Arm fat percentage (left)	0.2	0.7	1.3	0.2	1.1
Deep venous thrombosis (DVT) (self-reported)	0.2	0.3	0.4	-0.6	-0.5
Schizophrenia vs Biploar Disorder	0.1	0.1	0.1	-0.4	0.2
Alzheimer’s Disease (in mother)	0.1	0.2	0.3	0.5	-0.2
Alzheimer’s Disease (including proxy)	0.1	0.2	0.4	0.6	-0.0
Blood Eosinophil Count	0.1	0.6	1.0	1.0	-0.4
Type 2 Diabetes (T2D) (2018)	0.1	0.1	0.2	0.5	-0.1
Relative age of first facial hair	0.1	0.2	0.2	-0.4	0.5
Relative age voice broke	0.1	0.2	0.3	0.4	-0.5
Serious illness, injury or assault to yourself	0.1	0.2	0.2	-0.4	0.5
Stomach or abdominal pain in last month	0.1	0.2	0.3	0.1	-0.5
Hair/balding pattern: Pattern 2	0.1	0.1	0.2	-0.4	0.2
Pain all over the body in last month	0.1	0.1	0.2	0.2	-0.5
Asthma	0.1	0.1	0.3	-0.0	-0.5
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.1	0.1	-0.3	0.4
Hypothyroidism/myxoedema (self-reported)	0.1	0.2	0.3	-0.5	0.3
Body fat percentage	0.1	0.3	0.5	0.4	0.7
Mouth/teeth dental problems: Loose teeth	0.1	0.1	0.2	-0.0	0.4
Supplements: Vitamin C	0.1	0.1	0.2	-0.5	-0.1
Asthma (self-reported)	0.1	0.2	0.3	-0.1	-0.6
Guilty feelings	0.1	0.1	0.2	-0.4	-0.1
Ever taken oral contraceptive pill	0.1	0.1	0.1	-0.4	0.1
Alcohol drinker status: Never	0.1	0.2	0.2	0.5	0.3
Heart disease (siblings)	0.1	0.1	0.2	-0.2	-0.5
Intelligence (Savage-Jansen 2018)	0.0	0.2	0.3	-0.5	-0.1
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	0.0	0.0
Respiratory disease	0.0	0.1	0.1	-0.1	-0.4
Hair Pigment	0.0	0.5	0.7	0.8	-0.5
Tanning	0.0	0.3	0.4	-0.6	-0.4
Trunk fat percentage	0.0	0.0	0.1	0.2	-0.1
Qualifications: CSEs or equivalent	0.0	0.0	0.0	0.2	0.1
Alcohol usually taken with meals	0.0	0.0	0.0	-0.1	-0.1
Nervous feelings	0.0	0.0	0.0	-0.1	-0.1
Had menopause	0.0	0.0	0.0	-0.0	-0.0
Fluid intelligence score	0.0	0.1	0.1	0.3	0.2
Noisy workplace	0.0	0.0	0.0	-0.0	0.2
Tense / ‘highly strung’	0.0	0.0	0.0	0.0	-0.1
Loud music exposure frequency	0.0	0.0	0.0	0.0	-0.2
Exposure to tobacco smoke outside home	0.0	0.1	0.1	-0.3	-0.0
Suffer from ‘nerves’	0.0	0.1	0.1	0.2	0.2
Age at last live birth	0.0	0.0	0.1	0.2	-0.1
Handedness (chirality/laterality): Left-handed	0.0	0.1	0.1	0.2	-0.2
Average weekly champagne plus white wine intake	0.0	0.0	0.1	0.2	0.1
Average weekly beer plus cider intake	0.0	0.0	0.0	0.1	0.0
Myopia	0.0	0.0	0.0	0.2	0.1
Alcohol drinker status: Previous	0.0	0.0	0.1	0.2	-0.1

Hub : Genes

ATG9B

Models

Trait associations