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chr11:124,617,939-127,007,433

Best TWAS P=2.38e-14 · Best GWAS P=1.06e-17 conditioned to 0.0294

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	PATE2	0.11	0.03	bslmm	556	0.05	7.8e-07	2.5	-5.5	3.4e-08	0.29	0.92	0.02	TRUE
2	GTEx	Adipose Subcutaneous	EI24	0.09	0.01	lasso	6	0.00	4.6e-01	-5.0	5.4	7.7e-08	-0.18	0.08	0.80	FALSE
3	GTEx	Esophagus Muscularis	CDON	0.19	0.06	lasso	6	0.06	2.5e-04	-6.5	-7.5	6.9e-14	0.63	0.32	0.22	FALSE
4	GTEx	Esophagus Muscularis	RP11-680F20.12	0.14	0.06	lasso	3	0.04	2.2e-03	-6.5	-7.6	3.5e-14	0.63	0.17	0.22	TRUE
5	GTEx	Ovary	RP11-712L6.7	0.37	0.02	enet	9	0.07	6.9e-03	-4.7	5.1	2.9e-07	-0.06	0.09	0.07	TRUE
6	GTEx	Skin Sun Exposed Lower leg	FEZ1	0.07	0.03	lasso	5	0.04	3.1e-04	5.1	5.9	4.7e-09	-0.44	0.31	0.13	FALSE
7	GTEx	Thyroid	ST3GAL4	0.18	0.05	lasso	9	0.04	5.7e-04	-7.9	7.6	2.4e-14	-0.32	0.13	0.77	TRUE
8	The Cancer Genome Atlas	Breast Invasive Carcinoma	DDX25	0.14	0.12	lasso	2	0.12	1.9e-23	5.4	5.6	2.8e-08	-0.40	1.00	0.00	FALSE
9	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	DDX25	0.14	0.07	enet	14	0.08	5.0e-09	5.4	5.3	9.8e-08	-0.43	0.97	0.01	FALSE
10	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	DDX25	0.30	0.15	lasso	1	0.15	8.5e-09	5.4	5.4	7.1e-08	-0.40	0.98	0.00	FALSE
11	The Cancer Genome Atlas	Lung Adenocarcinoma	DDX25	0.11	0.06	lasso	1	0.06	3.4e-07	5.4	5.4	7.1e-08	-0.40	0.92	0.00	FALSE
12	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	DDX25	0.08	0.07	lasso	2	0.05	1.1e-06	5.4	5.5	5.1e-08	-0.40	0.96	0.00	FALSE
13	The Cancer Genome Atlas	Prostate Adenocarcinoma	DDX25	0.17	0.11	lasso	5	0.11	3.8e-11	5.4	5.3	1.3e-07	-0.41	1.00	0.00	FALSE
14	The Cancer Genome Atlas	Thyroid Carcinoma	DDX25	0.15	0.07	blup	78	0.09	4.3e-09	5.4	6.0	2.4e-09	-0.52	0.74	0.15	FALSE
15	The Cancer Genome Atlas	Thyroid Carcinoma	HYLS1	0.04	0.00	blup	56	0.01	2.6e-02	-4.7	7.6	3.1e-14	-0.45	0.02	0.67	FALSE