TWAS hub - TCIRG1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Esophagus Mucosa	0.3390	0.0810	4.9e-05	0.019	NA	0.075	NA	0.050	1.8e-02	NA	1.0e-05	NA	2.8e-04
2	GTEx	Esophagus Muscularis	0.0990	0.0500	9.5e-03	0.087	NA	0.035	NA	0.065	5.9e-06	NA	3.3e-03	NA	8.7e-05
3	YFS	Blood	0.0692	0.0189	9.8e-10	0.044	0.038	0.043	0.045	0.043	3.6e-14	1.3e-12	8.0e-14	1.8e-14	5.2e-14

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Height	5.9	113.0	256.0	9.1	16.0	0.6
Trunk predicted mass	5.7	32.3	73.1	4.7	8.6	-1.2
Standing height	5.7	56.4	127.7	6.5	11.3	0.2
Trunk fat-free mass	5.5	31.4	71.6	4.6	8.5	-1.2
Arm fat-free mass (right)	5.5	28.4	61.2	4.8	7.8	-1.1
Arm predicted mass (left)	5.5	28.2	61.3	4.6	7.8	-1.4
Whole body water mass	5.4	30.7	68.6	4.6	8.3	-1.6
Whole body fat-free mass	5.3	30.5	68.4	4.6	8.3	-1.6
Basal metabolic rate	5.3	29.5	64.5	4.6	8.0	-1.7
Forced vital capacity (FVC), Best measure	5.2	19.1	39.7	4.2	6.3	-0.1
Arm predicted mass (right)	5.2	26.8	58.8	4.5	7.7	-1.1
Arm fat-free mass (left)	5.1	26.0	58.4	4.2	7.6	-1.3
Weight	5.0	24.6	51.3	4.4	7.2	-1.7
Leg predicted mass (left)	4.9	25.9	56.1	4.1	7.5	-2.1
Leg fat-free mass (left)	4.8	25.4	55.1	4.1	7.4	-2.1
Forced expiratory volume in 1-second (FEV1), Best measure	4.8	15.4	34.0	3.5	5.8	-0.3
Comparative height size at age 10	4.7	25.8	60.7	3.8	7.8	1.6
Leg fat-free mass (right)	4.6	24.7	52.0	4.2	7.2	-2.1
Leg predicted mass (right)	4.6	24.3	51.1	4.1	7.2	-2.2
Peak expiratory flow (PEF)	4.4	10.3	23.7	2.6	4.9	-0.4
Supplements: Glucosamine	4.3	5.7	10.3	2.2	3.2	-1.4
Forced vital capacity (FVC)	4.3	16.6	38.1	3.3	6.2	0.7
Forced expiratory volume in 1-second (FEV1)	3.6	12.3	28.9	2.8	5.4	0.3
Headache pain in last month	3.6	6.2	8.9	-3.0	-2.3	2.1
Trunk fat mass	3.4	14.6	30.0	3.3	5.5	-1.7
Hip circumference	3.4	14.7	28.8	3.4	5.4	-1.9
Prostate Cancer	3.1	4.3	6.4	-2.0	-1.6	2.5
Bilateral oophorectomy (both ovaries removed)	3.0	3.5	5.3	-2.0	-1.1	2.3
Heel bone mineral density (BMD) T-score, automated (right)	2.9	6.7	8.4	2.9	2.6	-2.3
Whole body fat mass	2.8	11.8	23.8	2.9	4.9	-1.8
Heel T-Score	2.7	21.3	30.9	3.6	5.6	-4.4
Waist circumference	2.7	9.8	18.2	3.1	4.3	-1.4
Alcohol usually taken with meals	2.7	4.4	9.7	1.4	3.1	1.2
Hand grip strength (right)	2.5	6.7	10.5	3.0	3.2	-0.9
Tense / ‘highly strung’	2.4	4.0	7.6	-1.3	-2.8	-1.6
Pulse wave peak to peak time	2.4	2.8	5.1	0.8	1.6	-2.3
Emphysema/chronic bronchitis	2.4	2.7	7.0	1.1	0.1	-2.6
Leg fat mass (right)	2.4	9.2	17.8	2.5	4.2	-1.9
Illnesses of father: High blood pressure	2.4	2.9	5.5	-1.8	-2.3	0.1
Leg fat mass (left)	2.4	9.5	17.8	2.6	4.2	-1.9
Hand grip strength (left)	2.3	6.1	13.5	2.0	3.7	-0.8
Heel bone mineral density (BMD) T-score, automated (left)	2.3	5.3	5.8	2.4	2.2	-2.3
Forced expiratory volume in 1-second (FEV1), predicted	2.3	4.9	10.5	2.0	3.2	-0.5
Arm fat mass (left)	2.3	9.6	18.6	2.7	4.3	-1.8
Heart attack	2.2	2.8	5.5	-2.4	-1.6	-0.7
Birth weight of first child	2.2	3.9	9.0	0.6	3.0	1.6
Arm fat mass (right)	2.1	8.4	16.7	2.4	4.1	-1.7
Pulse wave Arterial Stiffness index	2.0	2.4	6.1	-0.4	-0.9	2.5
Risk taking	2.0	3.0	5.5	1.4	2.3	-1.2
Ever depressed for a whole week	2.0	2.5	4.5	1.7	2.1	-0.5
Medication: Metformin	1.9	2.7	4.7	1.7	2.2	-0.8
Diabetes (mother)	1.9	2.5	3.3	-1.8	-1.8	-0.9
Hearing difficulty/problems with background noise	1.9	3.0	6.2	-2.5	-1.4	0.9
Medication: Ramipril	1.9	2.4	5.0	-1.1	-2.2	1.1
Medication: Amlodipine	1.8	2.5	5.2	-2.3	-1.1	1.1
Mineral and other dietary supplements	1.8	2.4	2.9	-1.1	-1.7	1.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.8	3.9	6.7	2.2	2.6	-0.1
Heart attack/myocardial infarction (self-reported)	1.8	2.3	4.5	-2.1	-1.3	-0.9
Age at First Birth	1.7	2.4	3.8	1.8	1.9	-0.4
Trunk fat percentage	1.7	6.9	13.2	2.3	3.6	-1.4
Had other major operations	1.7	2.1	3.8	0.8	1.9	1.4
Hearing difficulty/problems: Yes	1.6	2.5	5.7	-2.4	-1.2	0.6
Sitting height	1.6	11.4	26.6	2.6	5.2	0.8
Medication: Seretide 50 evohaler	1.6	1.9	3.1	1.8	-0.2	1.6
Qualifications: NVQ or HND or HNC or equivalent	1.6	2.0	5.1	-0.9	-2.3	-0.1
Qualifications: nursing, teaching	1.6	2.4	3.8	0.2	1.8	2.0
Mouth/teeth dental problems: Bleeding gums	1.5	2.0	3.8	-0.8	-1.2	1.9
Hearing aid user	1.5	1.7	2.6	-1.6	-1.5	-0.5
Multivitamins +/- minerals	1.4	1.7	2.4	1.6	1.3	-1.0
Mouth/teeth dental problems	1.4	2.2	4.4	1.5	-0.2	-2.1
Breastfed as a baby	1.4	1.8	2.7	0.3	1.6	1.6
Number of children fathered	1.4	1.6	3.8	0.2	-0.9	-2.0
Medication: Aspirin	1.4	1.9	5.2	0.5	2.3	-0.4
Supplements: Vitamin C	1.4	1.7	2.1	-1.1	1.4	-1.5
Loneliness, isolation	1.4	1.9	2.8	1.5	0.9	-1.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.4	1.6	3.1	-1.8	-1.1	0.8
Average weekly champagne plus white wine intake	1.4	1.9	5.8	0.2	2.4	-0.0
Serious illness, injury or assault to yourself	1.3	1.6	4.1	0.1	2.0	0.8
Hair/balding pattern: Pattern 2	1.3	1.7	4.4	2.1	0.8	0.3
Body fat percentage	1.3	5.2	8.8	1.9	3.0	-1.7
Reason for reducing amount of alcohol drunk: Health precaution	1.3	1.5	2.8	-1.0	0.8	1.7
Handedness (chirality/laterality): Left-handed	1.3	1.5	3.0	-1.7	-0.5	1.2
Number of operations (self-reported)	1.3	1.9	3.8	1.3	0.5	1.9
Alcohol drinker status: Previous	1.3	1.5	2.6	-1.4	-1.6	0.2
Type 2 Diabetes (T2D) (2018)	1.2	2.2	4.0	0.8	1.4	-2.0
Pulse wave reflection index	1.2	1.5	3.0	-0.7	-1.0	1.7
Chronic bronchitis/emphysema (mother)	1.2	1.5	2.1	1.4	1.2	0.8
Chest pain or discomfort	1.2	1.8	3.8	-0.5	-1.1	2.0
Mouth/teeth dental problems: Mouth ulcers	1.2	1.9	3.2	-1.8	0.4	1.6
LDL Cholesterol	1.1	1.8	3.4	-1.4	-1.8	-0.0
Frequency of depressed mood in last 2 weeks	1.1	1.6	2.1	-1.2	-1.4	-1.1
Other serious medical condition/disability diagnosed by doctor	1.1	1.5	3.0	-1.1	0.2	1.7
Ever used hormone-replacement therapy (HRT)	1.1	1.4	2.4	1.1	0.9	1.5
Vitamin and mineral supplements	1.1	1.5	2.1	-1.3	-1.5	0.9
High blood pressure (mother)	1.1	1.5	3.5	-1.0	-0.1	-1.9
Ever unenthusiastic/disinterested for a whole week	1.1	1.4	2.0	1.4	1.4	-0.5
Mouth/teeth dental problems: Dentures	1.1	1.8	4.3	0.7	2.1	0.8
Medication: Lansoprazole	1.1	1.3	2.5	1.1	1.6	-0.4
High blood pressure (siblings)	1.1	1.6	3.2	-1.8	-1.3	0.3
Eye problems/disorders: Cataract	1.1	1.3	2.3	1.5	0.2	1.3
Ever taken oral contraceptive pill	1.1	1.3	2.1	0.8	1.0	-1.4
Mother’s age at death	1.1	1.4	2.6	1.0	1.6	-0.7
Average weekly beer plus cider intake	1.1	1.6	4.8	-0.3	-2.2	-0.3
Myopia	1.1	1.5	4.2	-2.0	0.6	0.2
Schizophrenia vs Biploar Disorder	1.0	1.3	3.9	2.0	0.0	0.1
Alzheimer’s Disease (in father)	1.0	1.1	2.4	0.7	1.5	-0.5
Ovarian Cancer	1.0	1.4	2.5	-1.3	0.0	-1.6
Crohns Disease (2012)	1.0	1.6	4.7	-0.1	-2.2	0.4
Time employed in main current job	1.0	1.2	3.0	-1.7	-0.7	0.3
Alcohol intake versus 10 years previously	1.0	1.6	3.7	-1.9	-1.0	-0.1
Hypothyroidism/myxoedema (self-reported)	1.0	1.9	5.5	0.3	0.5	2.4
Medication: Blood pressure	1.0	1.8	2.5	-1.6	-1.4	-1.0
Medication: Aspirin	1.0	1.3	3.7	0.2	1.9	-0.4
Financial situation satisfaction	1.0	1.2	2.1	-1.5	-0.5	-1.2
Pain type(s) experienced in last month: Hip pain	1.0	1.3	3.2	-0.7	-0.4	1.8
Alcohol drinker status: Never	1.0	1.2	3.2	-0.2	-0.6	-1.8
Schizophrenia (2018)	0.9	1.8	4.8	0.8	2.2	0.0
Alzheimer’s Disease (including proxy)	0.9	1.3	1.9	1.2	1.4	-0.6
Lupus	0.9	1.4	2.2	0.5	1.4	1.5
Schizophrenia (2014)	0.9	2.1	3.3	1.8	1.7	0.3
BMI	0.9	5.0	7.3	2.7	2.4	-1.3
Ever had hysterectomy (womb removed)	0.9	1.0	2.1	-0.9	-0.4	1.4
Maternal smoking around birth	0.9	1.2	3.5	0.5	-0.0	1.9
Medication: Atenolol	0.9	1.1	3.1	-0.4	1.8	-0.1
Body mass index (BMI)	0.9	3.9	5.3	1.6	2.3	-2.0
Diabetes (self-reported)	0.9	1.3	1.8	0.7	1.3	-1.4
Serious illness, injury or assault of a close relative in last 2 years	0.9	1.0	1.7	0.6	0.9	1.3
Diabetes diagnosed by doctor	0.9	1.5	2.2	0.7	1.4	-1.5
Commuting to job workplace: Walk	0.9	0.9	2.7	-0.3	-0.1	1.6
Supplements: Fish oil (including cod liver oil)	0.9	1.2	2.1	0.6	1.4	-1.1
Age started oral contraceptive pill	0.9	1.1	2.2	0.9	1.5	0.5
Unable to work because of sickness or disability	0.9	1.2	2.7	0.2	-0.9	1.6
Basal cell carcinoma (self-reported)	0.9	1.0	2.2	1.0	1.5	0.1
Intelligence (Savage-Jansen 2018)	0.8	2.5	5.1	2.3	1.6	-0.1
Verbal and Numeric Reasoning (VNR)	0.8	2.0	2.8	1.7	1.1	1.4
Systolic Blood Pressure	0.8	4.0	8.0	-2.8	-2.0	0.3
Cardiovascular Disease	0.8	2.6	5.6	-1.5	-2.4	0.1
Lung FVC	0.8	3.9	7.1	2.1	2.7	0.4
Nervous feelings	0.8	1.6	2.2	-1.5	-1.4	0.8
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.2	2.2	-1.5	-1.0	-0.5
Illnesses of mother	0.8	0.9	2.1	0.7	0.4	1.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.3	2.7	1.6	1.1	0.1
Medication for cholesterol, blood pressure or diabetes	0.8	1.3	2.9	1.7	0.9	-0.4
Leg fat percentage (right)	0.8	2.8	3.3	1.6	1.8	-1.6
Pulse rate, automated reading	0.8	2.5	3.6	1.9	0.4	-1.9
Alcohol intake frequency.	0.8	1.8	3.4	-1.8	-1.1	-0.9
Arm fat percentage (left)	0.8	3.2	4.5	1.3	2.1	-1.9
Smoking status: Current	0.8	1.2	2.0	1.3	-1.4	0.3
Guilty feelings	0.8	1.2	2.9	-0.8	0.3	1.7
Leg fat percentage (left)	0.8	2.9	3.0	1.7	1.7	-1.7
Ulcerative Colitis (UC)	0.7	1.3	3.9	-0.3	-2.0	0.2
Hypothyroidism (self reported)	0.7	1.6	3.6	0.7	0.8	1.9
Current tobacco smoking	0.7	1.2	2.8	1.7	-0.9	0.1
Relative age voice broke	0.7	1.0	1.6	1.3	0.4	-1.1
Qualifications: CSEs or equivalent	0.7	0.9	2.2	-0.6	-1.5	-0.3
Financial difficulties in last 2 years	0.7	1.0	2.5	0.2	-0.6	-1.6
Arm fat percentage (right)	0.7	2.8	4.1	1.0	2.0	-1.8
Medication: Paracetamol	0.7	1.1	2.6	-0.4	-1.6	-0.7
Mouth/teeth dental problems: Loose teeth	0.7	0.9	2.5	-0.2	0.2	1.6
Neck or shoulder pain in last month	0.7	0.9	2.6	0.0	-1.6	0.5
Migraine (self-reported)	0.7	0.8	2.1	-0.7	-1.4	0.0
Wears glasses or contact lenses	0.7	0.8	1.7	-1.3	-0.1	0.8
Irritability	0.7	1.2	3.1	-0.8	-1.8	-0.0
Ever had prostate specific antigen (PSA) test	0.7	0.8	2.2	0.0	0.5	-1.5
Pack years of smoking	0.7	1.1	2.6	0.1	0.8	1.6
Alzheimer’s Disease (in mother)	0.6	0.7	1.1	1.0	1.1	-0.1
Neuroticism (2016)	0.6	0.8	1.0	-0.9	-1.0	0.7
Primary Biliary Cirrhosis	0.6	0.8	1.6	1.3	0.3	0.9
Ulcerative Colitis	0.6	0.9	2.4	-0.3	-1.6	0.4
Townsend deprivation index at recruitment	0.6	0.8	2.2	0.3	-1.5	-0.3
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	1.6	-1.2	-0.3	0.6
Medication: Levothyroxine sodium	0.6	1.0	1.5	0.8	1.2	0.9
Hayfever/allergic rhinitis (self-reported)	0.6	0.8	1.1	0.5	-1.1	1.0
Father’s age at death	0.6	0.8	2.0	0.4	0.6	-1.4
Noisy workplace	0.6	0.7	1.5	-1.2	-0.7	0.0
Qualifications: A levels/AS levels or equivalent	0.6	1.3	1.7	1.3	1.2	1.0
Length of working week for main job	0.6	0.7	1.9	-0.4	-1.4	0.1
Glaucoma (self-reported)	0.6	0.8	1.6	0.3	0.7	1.3
Comparative body size at age 10	0.6	1.5	4.0	-0.2	2.0	-0.8
Worry too long after embarrassment	0.6	1.1	3.2	-0.1	-0.1	1.8
Heart disease (mother)	0.6	0.7	1.8	-1.4	0.4	-0.3
Age at last live birth	0.6	0.9	1.5	0.8	0.7	1.2
Family relationship satisfaction	0.6	0.8	1.8	0.6	0.5	1.4
Knee pain experienced in last month	0.6	1.0	1.9	0.8	1.4	-0.6
Illnesses of father: Heart disease	0.6	0.8	1.9	-1.4	0.4	0.7
Illnesses of siblings: Diabetes	0.6	0.8	1.6	-1.2	-0.9	0.2
Breast cancer (self-reported)	0.6	0.7	1.3	0.7	1.1	-0.6
Medication: Gliclazide	0.6	0.7	1.6	0.4	1.3	-0.5
Tinnitus: Yes, now most or all of the time	0.6	0.7	2.0	0.2	-0.5	1.4
Medication: Paracetamol	0.6	0.9	1.7	-0.8	-1.3	-0.6
Depression (Nagel 2018)	0.5	0.8	1.6	-0.5	-0.6	-1.3
Reaction Time	0.5	1.0	2.8	-1.7	-0.5	0.2
Triglycerides	0.5	0.8	1.0	-0.8	-0.9	-1.0
Angina	0.5	0.6	0.8	-0.9	-0.7	0.8
Medication for hormone replacement therapy	0.5	0.6	0.7	-0.7	-0.8	0.8
Pack years adult smoking proportion	0.5	0.8	2.2	0.1	0.3	1.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.7	1.3	0.8	-0.1	-1.1
Impedance of leg (left)	0.5	2.3	4.0	-0.2	-2.0	1.7
Had menopause	0.5	0.6	0.8	0.9	0.8	0.7
Illnesses of siblings	0.5	0.7	1.3	1.1	0.9	0.0
Hair/balding pattern: Pattern 3	0.5	0.7	1.2	-1.1	-0.9	0.6
Exposure to tobacco smoke at home	0.5	0.6	1.8	-0.0	-0.3	-1.3
Blood clot in the leg (DVT)	0.5	0.7	1.1	-1.0	1.1	0.1
Angina (self-reported)	0.5	0.7	0.9	-0.8	-1.0	0.8
Medication: Allopurinol	0.5	0.6	1.8	0.0	-0.3	1.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.5	1.6	1.3	0.1	-0.2
Osteoporosis (self-reported)	0.5	0.6	1.5	0.1	-1.2	0.6
Miserableness	0.5	0.9	1.5	-0.5	-1.2	0.9
Medication: Lisinopril	0.5	0.6	1.4	-0.6	1.2	-0.2
Fractured/broken bones in last 5 years	0.5	0.6	1.6	-0.1	-0.5	1.3
Commuting to job workplace: Cycle	0.5	0.5	0.6	0.8	0.7	-0.8
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	1.7	1.3	0.3	-0.2
Deep venous thrombosis (DVT) (self-reported)	0.5	0.6	1.1	-0.9	1.0	0.3
Worry (Nagel 2018)	0.4	0.8	1.0	-0.6	-1.0	-1.0
Irritable Bowel Disease (IBD)	0.4	1.0	1.9	0.2	-1.4	1.0
Body Mass Index (BMI) (2010)	0.4	0.5	1.0	-0.3	-0.6	-1.0
HbA1C	0.4	0.5	1.4	0.1	0.2	-1.2
HDL Cholesterol	0.4	0.7	1.8	0.5	-0.3	-1.3
Type 2 Diabetes (T2D) (2012)	0.4	0.5	0.8	0.5	-0.7	0.9
Blood Red Count	0.4	4.1	10.6	1.0	-0.8	3.2
Chronotype (morning person)	0.4	0.9	1.2	-0.9	1.1	0.9
Average weekly spirits intake	0.4	0.5	1.0	0.8	-0.0	-1.0
Sensitivity / hurt feelings	0.4	0.6	1.6	0.4	1.3	0.4
Relative age of first facial hair	0.4	0.9	2.4	0.5	-0.0	-1.6
Medication: Co-codamol	0.4	0.4	1.0	-0.3	0.4	1.0
Diabetes (father)	0.4	0.4	0.9	-0.6	1.0	0.2
Impedance of leg (right)	0.4	1.8	2.6	-0.4	-1.6	1.6
Hayfever, allergic rhinitis or eczema	0.4	0.8	1.8	1.3	0.1	0.9
Chronic bronchitis/emphysema (father)	0.4	0.4	0.9	0.2	-0.5	-1.0
Fluid intelligence score	0.4	0.9	1.1	0.9	0.9	1.0
Happiness	0.4	0.5	0.8	0.9	0.8	0.3
Depression (self-reported)	0.4	0.5	1.4	1.2	-0.3	-0.1
Lung cancer (father)	0.4	0.5	1.4	0.2	-1.2	-0.2
Loud music exposure frequency	0.4	0.5	1.4	-1.2	-0.1	0.3
Birth weight	0.4	0.9	2.3	0.6	1.5	0.4
Exposure to tobacco smoke outside home	0.4	0.5	0.8	-0.5	-0.8	-0.9
Age at first live birth	0.4	0.8	1.3	1.1	0.9	0.6
Mean time to correctly identify matches	0.4	0.7	1.9	-1.4	-0.1	0.5
Long-standing illness, disability or infirmity	0.4	0.6	1.2	-0.7	1.1	-0.4
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.4	0.6	-0.2	-0.8	0.8
Friendships satisfaction	0.4	0.4	1.2	-0.4	-0.0	1.1
Osteoarthritis (self-reported)	0.4	0.5	1.3	0.3	1.2	-0.1
Illnesses of father: None of the above (group 1)	0.4	0.5	1.3	1.1	0.2	0.2
Commuting to job workplace: Public transport	0.4	0.4	1.1	-0.2	1.1	-0.4
Medication: Blood pressure	0.4	0.7	2.2	0.1	0.0	1.5
High cholesterol (Self-reported)	0.4	0.7	2.0	0.1	-1.4	-0.3
Medication: Bendroflumethiazide	0.4	0.7	1.8	-0.5	-1.3	-0.1
Heart disease (siblings)	0.4	0.4	0.8	0.6	0.9	0.4
Bipolar Disorder or Schizophrenia	0.3	0.8	1.7	0.8	1.3	0.1
Breast Cancer	0.3	0.8	2.1	-0.6	-0.1	-1.4
Mean Putamen Volume	0.3	0.3	0.9	0.2	1.0	0.0
Blood Eosinophil Count	0.3	2.6	5.0	2.2	1.7	-0.2
Waist Hip Ratio (WHR)	0.3	1.2	2.0	0.6	1.4	1.1
Allergy or Eczema	0.3	0.8	2.2	1.5	-0.5	0.1
Hair Pigment	0.3	7.9	12.7	3.6	2.9	-1.6
Tanning	0.3	4.1	8.1	-2.9	-2.0	-0.3
Systolic blood pressure, automated reading	0.3	0.9	1.7	-1.3	0.4	0.9
Supplements: Zinc	0.3	0.4	0.5	-0.4	0.6	-0.7
Fed-up feelings	0.3	0.5	1.1	0.3	-1.1	0.4
Taking other prescription medications	0.3	0.5	1.1	1.1	0.3	0.5
Stomach or abdominal pain in last month	0.3	0.3	0.7	0.2	-0.8	0.5
Neuroticism score	0.3	0.5	1.1	0.1	-1.0	0.7
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	0.8	-0.8	-0.9	-0.2
Falls in the last year	0.3	0.4	1.1	-1.0	0.1	-0.0
Number of live births	0.3	0.5	1.1	-0.0	-0.6	1.0
Ever highly irritable/argumentative for 2 days	0.3	0.4	0.6	-0.2	-0.8	-0.7
Qualifications: O levels/GCSEs or equivalent	0.3	0.5	0.9	1.0	0.8	0.0
Medication: Ventolin 100micrograms inhaler	0.3	0.4	0.8	-0.2	-0.9	-0.6
Number of full brothers	0.3	0.4	0.5	-0.7	-0.7	-0.1
Wheeze or whistling in the chest in last year	0.3	0.5	0.9	0.1	-0.9	0.7
Medication: Ibuprofen	0.3	0.3	0.7	0.2	0.9	0.4
Medication: Omeprazole	0.3	0.3	0.5	0.7	-0.1	0.7
Commuting to job workplace: Car/motor vehicle	0.3	0.3	0.4	0.5	-0.6	-0.6
Smoking status: Previous	0.3	0.4	1.0	-1.0	-0.1	0.6
Impedance of whole body	0.3	1.6	2.8	-0.4	-1.7	1.4
Crohns Disease (2017)	0.2	0.5	0.9	1.0	-0.2	0.7
Major Depression (MDD)	0.2	0.2	0.5	0.2	0.0	-0.7
Fasting Glucose	0.2	0.3	0.7	0.8	-0.3	-0.0
Blood Platelet Count	0.2	1.9	2.2	1.3	-1.4	-1.5
Smoking Status	0.2	0.5	1.5	1.2	-0.1	-0.1
Respiratory disease	0.2	0.4	0.7	0.8	-0.8	-0.2
Average weekly fortified wine intake	0.2	0.3	0.8	-0.1	0.2	0.9
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.6	-0.3	0.2	0.8
High blood pressure	0.2	0.4	0.9	-0.6	-1.0	0.1
Past tobacco smoking	0.2	0.3	0.4	0.5	0.6	-0.5
Allergy	0.2	0.6	1.5	-1.2	0.1	0.4
Pain all over the body in last month	0.2	0.2	0.5	0.7	-0.0	-0.5
Worrier / anxious feelings	0.2	0.4	0.6	0.1	-0.7	-0.7
Asthma	0.2	0.4	0.9	0.6	-1.0	0.1
Qualifications: College or University degree	0.2	0.6	0.7	0.8	0.8	-0.8
Eye problems/disorders: None of the above	0.2	0.2	0.4	-0.3	0.5	-0.6
Medication for pain relief, constipation, heartburn	0.2	0.3	0.6	-0.3	-0.2	0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.3	0.8	-0.0	-0.0	-0.9
Suffer from ‘nerves’	0.2	0.4	0.9	-0.4	-0.9	0.1
Had major operations	0.2	0.2	0.4	0.2	0.6	0.3
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	0.4	-0.0	-0.6	-0.5
Hypertension (Self-reported)	0.2	0.4	1.0	-0.5	-1.0	0.1
Ever had bowel cancer screening	0.2	0.3	0.4	-0.3	0.5	0.7
Medication for cholesterol	0.2	0.3	0.6	-0.6	-0.2	-0.8
Back pain experienced in last month	0.2	0.3	0.8	0.9	0.2	-0.3
Asthma (self-reported)	0.2	0.4	0.9	0.4	-1.0	0.3
Eye problems/disorders: Glaucoma	0.2	0.2	0.3	0.6	0.1	0.5
Vascular/heart problems diagnosed by doctor	0.2	0.5	1.1	0.5	1.1	-0.1
Cholesterol lowering medication	0.2	0.2	0.5	0.7	-0.2	-0.4
Pain experienced in last month	0.2	0.4	0.9	-0.5	-0.2	-0.9
Bipolar Disorder (2018)	0.1	0.1	0.3	0.5	-0.1	-0.0
Depressed Affect (Nagel 2018)	0.1	0.2	0.2	0.3	-0.4	0.5
Neuroticism (Nagel 2018)	0.1	0.1	0.2	-0.5	-0.4	0.2
Rheumatoid Arthritis	0.1	0.2	0.3	-0.5	-0.3	-0.4
Blood White Count	0.1	0.7	2.0	-0.4	-1.4	0.4
Lung FEV1/FVC ratio	0.1	0.4	0.8	0.3	0.9	0.5
Neuroticism	0.1	0.1	0.4	-0.0	-0.6	0.1
Number of treatments/medications taken	0.1	0.2	0.3	-0.5	-0.3	-0.4
Eye problems/disorders: Diabetes related eye disease	0.1	0.1	0.4	-0.1	-0.6	-0.0
Age when periods started (menarche)	0.1	0.2	0.4	-0.0	-0.4	-0.6
Number of incorrect matches in round	0.1	0.1	0.4	-0.6	0.1	-0.1
Qualifications: None of the above	0.1	0.3	0.8	0.1	-0.9	-0.2
Medication: Simvastatin	0.1	0.1	0.2	-0.2	-0.5	-0.2
Impedance of arm (right)	0.1	0.6	1.1	-0.6	-1.1	0.6
Pulse rate	0.1	0.2	0.3	0.4	0.3	-0.6
Medication: Cholesterol lowering	0.1	0.1	0.3	-0.6	-0.0	-0.3
Prospective memory result	0.1	0.1	0.3	-0.2	0.6	-0.1
Impedance of arm (left)	0.1	0.7	1.0	-0.1	-1.0	1.0
Hair/balding pattern: Pattern 4	0.1	0.1	0.2	-0.3	0.4	-0.4
Gout (self-reported)	0.1	0.1	0.2	0.2	-0.3	0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.1	0.1	-0.2	-0.4	0.2
Health satisfaction	0.1	0.1	0.2	-0.3	-0.2	-0.5
Shortness of breath walking on level ground	0.1	0.1	0.1	0.3	0.4	-0.0
Number of full sisters	0.1	0.1	0.3	-0.0	-0.2	0.5
Overall health rating	0.1	0.2	0.3	-0.5	-0.3	-0.5
Leg pain on walking	0.1	0.1	0.3	0.3	0.3	-0.5
Average weekly red wine intake	0.1	0.1	0.1	-0.2	-0.3	0.4
Mood swings	0.1	0.2	0.6	0.8	-0.1	-0.2
Number of self-reported non-cancer illnesses	0.1	0.2	0.5	0.7	0.4	0.1
Diastolic blood pressure, automated reading	0.1	0.2	0.3	-0.5	-0.4	-0.6
Supplements: Calcium	0.1	0.1	0.2	-0.1	-0.5	-0.2
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.1	0.1	-0.4	0.0	0.1
Severe depression (siblings)	0.0	0.0	0.1	-0.3	0.0	0.1
Medication: Ibuprofen (e.g. Nurofen)	0.0	0.0	0.1	-0.0	0.0	0.3
Medication: Atorvastatin	0.0	0.0	0.0	0.1	-0.1	0.2
Ever smoked	0.0	0.0	0.1	0.2	0.1	0.3

Hub : Genes

TCIRG1

Models

Trait associations