[Hub]/) : Traits : Body mass index (BMI) : ← →

chr2:218,736,292-220,804,712

Best TWAS P=8.27e-10 · Best GWAS P=1.57e-08 conditioned to 0.00307

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PLCD4 0.06 0.09 blup 382 0.09 1.3e-10 4.8 -5.2 1.8e-07 -0.02 0.15 0.84 FALSE
2 GTEx Brain Cerebellar Hemisphere RQCD1 0.13 0.04 lasso 11 0.01 2.1e-01 4.6 5.5 2.8e-08 0.05 0.07 0.50 FALSE
3 GTEx Breast Mammary Tissue BCS1L 0.05 0.03 enet 7 0.03 6.8e-03 -5.1 -6.1 8.3e-10 0.02 0.07 0.79 TRUE
4 GTEx Breast Mammary Tissue (Female) BCS1L 0.06 0.03 lasso 1 -0.01 7.1e-01 -5.1 -5.1 2.9e-07 0.08 0.04 0.24 FALSE
5 GTEx Esophagus Mucosa TTLL4 0.08 0.08 enet 15 0.08 4.3e-06 -5.1 5.3 9.4e-08 -0.07 0.05 0.95 FALSE
6 GTEx Muscle Skeletal WNT6 0.16 0.02 enet 54 0.07 1.2e-07 -1.4 -5.3 1.1e-07 0.21 0.20 0.23 FALSE
7 GTEx Testis CYP27A1 0.20 0.18 lasso 4 0.26 4.0e-12 -5.0 5.3 1.2e-07 -0.05 0.09 0.91 FALSE
8 GTEx Testis GLB1L 0.34 0.24 lasso 9 0.27 2.3e-12 -4.4 5.3 1.3e-07 -0.60 0.56 0.42 TRUE
9 GTEx Whole Blood CYP27A1 0.03 0.05 lasso 5 0.02 1.3e-02 4.8 5.2 1.8e-07 -0.01 0.15 0.74 FALSE
10 GTEx Whole Blood RQCD1 0.04 0.02 lasso 2 0.00 2.4e-01 4.8 -5.2 1.5e-07 0.00 0.11 0.56 FALSE
11 METSIM Adipose CYP27A1 0.06 0.04 lasso 7 0.04 1.1e-06 4.8 5.3 1.5e-07 -0.04 0.17 0.82 FALSE
12 NTR Blood CYP27A1 0.21 0.30 enet 44 0.31 3.8e-104 4.8 5.7 9.7e-09 -0.07 0.31 0.68 FALSE
13 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma VIL1 0.02 0.01 blup 50 0.01 8.6e-03 4.7 -5.4 5.4e-08 -0.06 0.02 0.64 FALSE
14 The Cancer Genome Atlas Lung Adenocarcinoma SLC11A1 0.03 0.03 blup 51 0.03 1.4e-04 4.3 5.8 9.0e-09 0.01 0.09 0.40 FALSE