[Hub]/) : Traits : Body fat percentage : ← →

chr2:24,324,172-27,649,375

Best TWAS P=9.14e-47 · Best GWAS P=1.32e-38 conditioned to 0.237

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ADCY3	0.16	0.12	lasso	10	0.14	3.2e-17	12.69	-14.4	9.1e-47	-0.87	0.01	0.99	TRUE
2	CommonMind	Brain Pre-frontal Cortex	CENPO	0.07	0.03	bslmm	322	0.03	7.0e-05	8.16	-10.2	1.9e-24	-0.49	0.46	0.27	FALSE
3	GTEx	Adipose Subcutaneous	ADCY3	0.07	0.04	lasso	6	0.01	3.2e-02	11.94	11.5	1.3e-30	0.86	0.07	0.91	FALSE
4	GTEx	Adipose Subcutaneous	RP11-443B20.1	0.04	0.00	enet	10	0.00	1.2e-01	7.54	10.1	6.9e-24	0.81	0.04	0.90	FALSE
5	GTEx	Adrenal Gland	PTRHD1	0.32	0.28	lasso	3	0.26	8.3e-10	-6.00	6.5	8.8e-11	0.41	0.98	0.00	FALSE
6	GTEx	Artery Coronary	DNAJC27	0.12	0.03	lasso	7	0.00	2.4e-01	2.89	5.1	2.9e-07	0.46	0.14	0.22	FALSE
7	GTEx	Artery Tibial	ADCY3	0.21	0.14	lasso	6	0.15	4.3e-12	11.34	12.7	4.7e-37	0.69	0.98	0.02	FALSE
8	GTEx	Artery Tibial	RP11-443B20.1	0.17	0.08	enet	40	0.09	8.2e-08	11.34	10.9	1.0e-27	0.59	0.46	0.50	FALSE
9	GTEx	Cells EBV-transformed lymphocytes	ADCY3	0.25	0.23	enet	10	0.12	9.2e-05	11.94	-9.9	2.5e-23	-0.84	0.02	0.97	FALSE
10	GTEx	Cells EBV-transformed lymphocytes	RP11-443B20.1	0.13	0.13	enet	9	0.05	9.2e-03	11.94	-12.2	2.1e-34	-0.93	0.01	0.96	FALSE
11	GTEx	Nerve Tibial	ADCY3	0.09	0.05	enet	6	0.03	2.2e-03	11.34	-13.5	1.1e-41	-0.91	0.01	0.99	FALSE
12	GTEx	Nerve Tibial	RP11-443B20.1	0.07	0.03	enet	6	0.02	1.1e-02	11.34	-13.1	3.7e-39	-0.81	0.03	0.96	FALSE
13	GTEx	Prostate	EPT1	0.21	-0.01	enet	23	0.00	3.2e-01	-2.92	-5.4	5.8e-08	0.01	0.08	0.06	TRUE
14	GTEx	Whole Blood	DNAJC27	0.08	0.10	lasso	1	0.10	2.2e-09	11.76	11.8	6.4e-32	0.80	0.89	0.11	FALSE
15	GTEx	Whole Blood	ADCY3	0.23	0.24	enet	24	0.27	5.5e-25	12.13	13.2	6.2e-40	0.86	0.98	0.02	FALSE
16	GTEx	Whole Blood	RP11-443B20.1	0.21	0.17	enet	32	0.20	1.8e-18	11.76	13.6	5.5e-42	0.86	0.77	0.23	FALSE
17	METSIM	Adipose	EFR3B	0.04	0.00	bslmm	357	0.00	9.7e-02	-0.61	-6.9	6.1e-12	-0.37	0.06	0.08	FALSE
18	ROSMAP	Brain Pre-frontal Cortex	ADCY3	0.17	0.26	enet	32	0.26	6.8e-33	12.13	-13.2	5.3e-40	-0.89	0.81	0.19	FALSE
19	ROSMAP	Brain Pre-frontal Cortex	CENPO	0.08	0.04	enet	5	0.05	2.6e-07	-3.92	-5.4	7.0e-08	-0.36	1.00	0.00	FALSE
20	ROSMAP	Brain Pre-frontal Cortex	KCNK3	0.24	0.15	lasso	3	0.15	6.5e-19	6.13	-6.2	7.2e-10	0.03	0.00	1.00	TRUE
21	YFS	Blood	ADCY3	0.07	0.02	bslmm	343	0.04	7.3e-14	12.95	-7.3	2.5e-13	-0.61	0.00	1.00	FALSE
22	YFS	Blood	POMC	0.35	0.05	enet	71	0.19	5.7e-59	-7.74	-6.5	6.8e-11	-0.31	1.00	0.00	FALSE
23	The Cancer Genome Atlas	Breast Invasive Carcinoma	ADCY3	0.05	0.03	blup	81	0.03	5.0e-07	0.60	-6.2	7.5e-10	-0.50	0.63	0.32	FALSE
24	The Cancer Genome Atlas	Breast Invasive Carcinoma	POMC	0.08	0.05	lasso	3	0.06	2.6e-12	-1.37	-5.6	2.0e-08	-0.20	0.97	0.03	FALSE
25	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	POMC	0.06	0.00	enet	12	0.03	9.3e-05	-1.37	-6.5	7.8e-11	-0.27	0.01	0.41	FALSE
26	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	EFR3B	0.03	0.05	lasso	1	0.04	1.9e-05	-9.78	-9.8	1.3e-22	-0.67	0.56	0.06	FALSE
27	The Cancer Genome Atlas	Brain Lower Grade Glioma	ADCY3	0.03	0.02	blup	81	0.02	7.1e-04	7.77	-11.4	3.7e-30	-0.87	0.04	0.93	FALSE
28	The Cancer Genome Atlas	Lung Adenocarcinoma	DNAJC27	0.05	0.01	blup	46	0.04	3.2e-05	2.88	-6.4	1.4e-10	-0.55	0.35	0.59	FALSE
29	The Cancer Genome Atlas	Lung Adenocarcinoma	POMC	0.14	0.04	enet	7	0.08	5.3e-10	-1.37	-6.6	3.4e-11	-0.22	0.38	0.62	FALSE
30	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	POMC	0.19	0.01	blup	38	0.05	1.5e-04	-7.74	-6.1	8.8e-10	-0.33	0.01	0.56	FALSE
31	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	POMC	0.22	0.05	blup	37	0.03	2.1e-02	-1.94	-6.0	2.0e-09	-0.12	0.01	0.29	FALSE
32	The Cancer Genome Atlas	Prostate Adenocarcinoma	POMC	0.11	0.08	enet	7	0.09	1.6e-09	-1.37	-6.4	1.2e-10	-0.24	0.92	0.06	FALSE