[Hub]/) : Traits : Body fat percentage : ← →

chr6:33,745,071-36,804,187

Best TWAS P=2.15e-30 · Best GWAS P=9.38e-24 conditioned to 0.0774

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	C6orf106	0.29	0.21	bslmm	382	0.23	6.9e-28	9.6	7.7	1.6e-14	0.85	0.05	0.95	FALSE
2	CommonMind	Brain Pre-frontal Cortex	PACSIN1	0.07	0.01	lasso	6	0.02	1.1e-03	10.0	7.0	2.5e-12	0.81	0.05	0.86	FALSE
3	CommonMind	Brain Pre-frontal Cortex	SNRPC	0.10	0.16	lasso	4	0.15	3.6e-18	10.0	-10.4	1.9e-25	-0.65	0.04	0.96	FALSE
4	CommonMind	Brain Pre-frontal Cortex	UHRF1BP1	0.17	0.23	lasso	19	0.22	5.8e-27	10.0	10.0	1.4e-23	0.59	0.04	0.96	FALSE
5	GTEx	Adipose Subcutaneous	UHRF1BP1	0.30	0.35	enet	28	0.36	1.6e-30	10.0	10.4	2.4e-25	0.60	0.04	0.96	FALSE
6	GTEx	Adipose Subcutaneous	SNRPC	0.13	0.13	enet	21	0.13	1.2e-10	10.0	-9.3	1.4e-20	-0.41	0.04	0.96	FALSE
7	GTEx	Adipose Visceral Omentum	UHRF1BP1	0.30	0.34	lasso	3	0.34	3.0e-18	10.0	10.0	1.7e-23	0.59	0.04	0.96	FALSE
8	GTEx	Adrenal Gland	UHRF1BP1	0.32	0.26	enet	33	0.33	1.3e-12	10.0	7.0	1.8e-12	0.30	0.04	0.96	FALSE
9	GTEx	Adrenal Gland	SNRPC	0.13	0.04	lasso	6	0.03	2.7e-02	9.9	-9.5	2.4e-21	-0.56	0.06	0.78	FALSE
10	GTEx	Artery Aorta	ANKS1A	0.10	0.10	lasso	2	0.08	2.4e-05	-7.2	-7.5	7.9e-14	-0.17	0.32	0.21	FALSE
11	GTEx	Artery Aorta	UHRF1BP1	0.35	0.32	lasso	10	0.30	7.7e-17	10.0	10.0	1.3e-23	0.59	0.04	0.96	FALSE
12	GTEx	Artery Coronary	UHRF1BP1	0.33	0.36	lasso	2	0.35	1.6e-12	10.0	10.0	2.1e-23	0.59	0.04	0.96	FALSE
13	GTEx	Artery Tibial	UHRF1BP1	0.31	0.43	lasso	11	0.43	4.0e-36	10.0	9.6	5.4e-22	0.53	0.04	0.96	FALSE
14	GTEx	Artery Tibial	SNRPC	0.06	0.06	lasso	4	0.05	1.3e-04	10.0	-10.0	1.1e-23	-0.62	0.04	0.96	FALSE
15	GTEx	Brain Caudate basal ganglia	UHRF1BP1	0.19	0.14	lasso	7	0.12	3.1e-04	10.0	9.4	6.4e-21	0.46	0.04	0.90	FALSE
16	GTEx	Brain Caudate basal ganglia	SNRPC	0.19	0.15	lasso	3	0.06	7.7e-03	10.0	-10.7	1.1e-26	-0.65	0.04	0.92	FALSE
17	GTEx	Brain Cerebellar Hemisphere	UHRF1BP1	0.22	0.16	lasso	12	0.15	1.0e-04	10.0	9.8	9.5e-23	0.64	0.04	0.91	FALSE
18	GTEx	Brain Cerebellum	UHRF1BP1	0.14	0.09	enet	23	0.12	1.5e-04	10.0	8.9	6.3e-19	0.51	0.04	0.83	FALSE
19	GTEx	Brain Cortex	C6orf106	0.22	0.07	enet	16	0.10	1.1e-03	10.0	7.2	5.0e-13	0.73	0.04	0.92	FALSE
20	GTEx	Brain Putamen basal ganglia	UHRF1BP1	0.20	0.17	lasso	2	0.16	1.5e-04	9.9	10.0	1.6e-23	0.59	0.04	0.85	FALSE
21	GTEx	Breast Mammary Tissue	UHRF1BP1	0.34	0.28	enet	46	0.29	4.7e-15	10.0	9.8	1.5e-22	0.51	0.04	0.96	FALSE
22	GTEx	Breast Mammary Tissue (Male)	UHRF1BP1	0.19	0.16	enet	24	0.08	5.6e-03	9.9	10.1	4.5e-24	0.59	0.04	0.91	FALSE
23	GTEx	Breast Mammary Tissue (Female)	UHRF1BP1	0.23	0.21	lasso	3	0.20	1.0e-06	10.0	9.6	5.9e-22	0.50	0.04	0.96	FALSE
24	GTEx	Cells EBV-transformed lymphocytes	UHRF1BP1	0.37	0.08	enet	46	0.11	1.7e-04	10.0	6.7	3.0e-11	0.52	0.04	0.91	FALSE
25	GTEx	Cells EBV-transformed lymphocytes	C6orf106	0.20	0.00	lasso	5	0.00	2.7e-01	9.2	8.0	1.5e-15	0.82	0.05	0.27	FALSE
26	GTEx	Cells Transformed fibroblasts	TEAD3	0.36	0.29	enet	27	0.32	8.4e-25	-7.0	5.8	6.6e-09	-0.01	0.98	0.02	FALSE
27	GTEx	Cells Transformed fibroblasts	DEF6	0.14	0.03	enet	35	0.04	9.7e-04	5.1	-7.8	9.2e-15	-0.16	0.60	0.02	FALSE
28	GTEx	Cells Transformed fibroblasts	UHRF1BP1	0.34	0.32	enet	44	0.31	2.4e-23	10.0	10.6	3.4e-26	0.65	0.04	0.96	FALSE
29	GTEx	Colon Sigmoid	UHRF1BP1	0.44	0.36	lasso	12	0.38	1.8e-14	10.0	9.5	1.4e-21	0.45	0.04	0.96	FALSE
30	GTEx	Colon Transverse	UHRF1BP1	0.42	0.28	lasso	4	0.28	1.6e-13	10.0	10.3	6.7e-25	0.64	0.04	0.96	FALSE
31	GTEx	Colon Transverse	C6orf106	0.15	0.05	lasso	1	0.03	1.5e-02	8.2	8.2	2.4e-16	0.61	0.11	0.39	FALSE
32	GTEx	Esophagus Gastroesophageal Junction	UHRF1BP1	0.47	0.38	enet	22	0.43	7.3e-17	8.9	8.4	3.7e-17	0.51	0.05	0.95	FALSE
33	GTEx	Esophagus Mucosa	UHRF1BP1	0.14	0.15	enet	28	0.17	1.3e-11	9.9	10.4	1.9e-25	0.65	0.04	0.96	FALSE
34	GTEx	Esophagus Mucosa	SNRPC	0.12	0.10	lasso	2	0.08	4.8e-06	10.0	-10.0	1.7e-23	-0.59	0.04	0.96	FALSE
35	GTEx	Esophagus Muscularis	UHRF1BP1	0.42	0.35	enet	48	0.33	1.0e-20	10.0	10.4	2.5e-25	0.46	0.04	0.96	FALSE
36	GTEx	Esophagus Muscularis	SNRPC	0.09	0.11	lasso	3	0.07	3.8e-05	10.0	-9.6	6.8e-22	-0.60	0.04	0.96	FALSE
37	GTEx	Heart Atrial Appendage	UHRF1BP1	0.13	0.07	enet	17	0.05	1.9e-03	10.0	8.5	1.6e-17	0.38	0.04	0.93	FALSE
38	GTEx	Heart Atrial Appendage	MAPK13	0.12	0.00	lasso	5	0.00	3.1e-01	6.6	-6.4	1.5e-10	-0.01	0.02	0.79	TRUE
39	GTEx	Heart Left Ventricle	UHRF1BP1	0.23	0.12	lasso	7	0.22	1.2e-11	10.0	7.3	2.4e-13	0.34	0.04	0.96	FALSE
40	GTEx	Liver	UHRF1BP1	0.13	0.04	lasso	3	0.05	1.8e-02	10.0	9.9	5.0e-23	0.52	0.04	0.78	FALSE
41	GTEx	Lung	UHRF1BP1	0.17	0.20	enet	22	0.18	4.3e-14	10.0	10.5	6.4e-26	0.57	0.04	0.96	FALSE
42	GTEx	Muscle Skeletal	UHRF1BP1	0.34	0.34	enet	45	0.39	4.3e-40	10.0	8.7	4.2e-18	0.33	0.04	0.96	FALSE
43	GTEx	Muscle Skeletal	SNRPC	0.03	0.02	lasso	3	0.02	8.3e-03	10.0	-10.6	2.4e-26	-0.69	0.04	0.90	FALSE
44	GTEx	Muscle Skeletal	C6orf106	0.08	0.06	lasso	4	0.06	7.1e-07	9.8	-9.9	4.5e-23	-0.89	0.09	0.90	FALSE
45	GTEx	Nerve Tibial	UHRF1BP1	0.31	0.31	lasso	6	0.31	3.9e-22	10.0	10.1	4.1e-24	0.58	0.04	0.96	FALSE
46	GTEx	Nerve Tibial	SNRPC	0.12	0.10	lasso	4	0.08	1.5e-06	10.0	-10.0	1.8e-23	-0.60	0.04	0.96	FALSE
47	GTEx	Nerve Tibial	C6orf106	0.11	0.07	enet	17	0.07	1.3e-05	9.8	8.1	7.1e-16	0.88	0.04	0.94	FALSE
48	GTEx	Pancreas	C6orf106	0.14	0.11	enet	11	0.13	2.8e-06	9.9	9.6	8.4e-22	0.88	0.06	0.93	FALSE
49	GTEx	Skin Not Sun Exposed Suprapubic	UHRF1BP1	0.20	0.10	enet	30	0.15	2.1e-08	9.9	7.1	9.3e-13	0.20	0.05	0.95	FALSE
50	GTEx	Skin Not Sun Exposed Suprapubic	SNRPC	0.18	0.04	enet	37	0.03	1.0e-02	9.8	-5.2	2.1e-07	-0.17	0.05	0.82	FALSE
51	GTEx	Skin Sun Exposed Lower leg	UHRF1BP1	0.19	0.13	enet	33	0.14	2.7e-11	10.0	10.1	3.6e-24	0.52	0.04	0.96	FALSE
52	GTEx	Skin Sun Exposed Lower leg	SNRPC	0.03	0.04	lasso	2	0.03	1.9e-03	10.0	-10.0	1.6e-23	-0.59	0.04	0.93	FALSE
53	GTEx	Small Intestine Terminal Ileum	UHRF1BP1	0.20	0.03	lasso	5	0.00	3.4e-01	10.0	10.7	1.2e-26	0.60	0.04	0.70	FALSE
54	GTEx	Spleen	UHRF1BP1	0.34	0.21	enet	36	0.17	4.5e-05	10.0	9.7	3.5e-22	0.54	0.04	0.93	FALSE
55	GTEx	Stomach	UHRF1BP1	0.24	0.22	enet	20	0.23	2.2e-11	9.9	11.0	2.9e-28	0.58	0.04	0.96	FALSE
56	GTEx	Thyroid	UHRF1BP1	0.13	0.06	enet	37	0.08	5.9e-07	5.1	7.5	6.0e-14	0.23	0.22	0.78	FALSE
57	GTEx	Thyroid	SNRPC	0.07	0.04	lasso	6	0.05	1.6e-04	10.0	-10.0	1.6e-23	-0.57	0.04	0.96	FALSE
58	GTEx	Thyroid	C6orf106	0.09	0.01	enet	29	0.01	1.1e-01	10.0	6.0	1.6e-09	0.75	0.04	0.57	FALSE
59	GTEx	Uterus	UHRF1BP1	0.20	0.03	lasso	4	0.07	1.8e-02	10.0	11.5	2.1e-30	0.73	0.04	0.63	TRUE
60	GTEx	Vagina	UHRF1BP1	0.31	0.05	lasso	8	0.04	5.0e-02	10.0	10.4	3.2e-25	0.59	0.04	0.76	FALSE
61	GTEx	Whole Blood	UHRF1BP1	0.14	0.14	lasso	7	0.14	2.9e-13	10.0	10.4	2.8e-25	0.55	0.04	0.96	FALSE
62	METSIM	Adipose	C6orf106	0.04	0.02	blup	381	0.02	7.7e-04	6.1	6.3	2.8e-10	0.62	0.11	0.74	FALSE
63	METSIM	Adipose	PPARD	0.04	0.00	enet	19	0.01	3.9e-03	-4.0	6.7	1.9e-11	0.06	0.10	0.02	TRUE
64	METSIM	Adipose	SNRPC	0.05	0.05	lasso	7	0.07	2.9e-11	10.0	-7.9	2.5e-15	-0.32	0.04	0.96	FALSE
65	METSIM	Adipose	UHRF1BP1	0.16	0.31	enet	30	0.32	1.0e-49	10.0	9.3	1.3e-20	0.50	0.03	0.97	FALSE
66	NTR	Blood	C6orf106	0.03	0.02	lasso	6	0.02	7.2e-07	10.0	9.6	8.1e-22	0.96	0.05	0.95	FALSE
67	NTR	Blood	UHRF1BP1	0.03	0.05	enet	19	0.05	7.4e-15	9.9	10.0	1.1e-23	0.64	0.04	0.96	FALSE
68	ROSMAP	Brain Pre-frontal Cortex	UHRF1BP1	0.16	0.27	lasso	10	0.28	2.7e-36	9.9	9.9	6.3e-23	0.55	0.04	0.96	FALSE
69	ROSMAP	Brain Pre-frontal Cortex	SNRPC	0.15	0.27	lasso	4	0.27	4.0e-35	10.0	-10.1	7.9e-24	-0.59	0.04	0.96	FALSE
70	ROSMAP	Brain Pre-frontal Cortex	C6orf106	0.30	0.26	bslmm	372	0.33	9.3e-44	10.0	7.4	1.2e-13	0.84	0.04	0.96	FALSE
71	YFS	Blood	SNRPC	0.02	0.03	lasso	5	0.02	3.0e-08	8.9	-8.8	1.7e-18	-0.64	0.28	0.72	FALSE
72	YFS	Blood	UHRF1BP1	0.18	0.34	enet	36	0.34	2.5e-117	10.0	10.1	8.6e-24	0.64	0.03	0.97	FALSE
73	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	UHRF1BP1	0.03	0.04	lasso	3	0.04	1.7e-04	10.0	10.0	1.9e-23	0.59	0.02	0.94	FALSE
74	The Cancer Genome Atlas	Breast Invasive Carcinoma	SNRPC	0.01	0.01	blup	31	0.00	3.0e-02	5.5	-10.2	3.2e-24	-0.56	0.01	0.65	FALSE
75	The Cancer Genome Atlas	Breast Invasive Carcinoma	UHRF1BP1	0.04	0.05	lasso	3	0.04	8.4e-09	10.0	10.0	9.7e-24	0.59	0.02	0.98	FALSE
76	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	UHRF1BP1	0.07	0.11	lasso	3	0.07	2.6e-04	10.0	10.0	2.2e-23	0.59	0.02	0.97	FALSE
77	The Cancer Genome Atlas	Colon Adenocarcinoma	UHRF1BP1	0.08	0.11	lasso	12	0.10	2.3e-06	10.0	9.9	2.8e-23	0.58	0.02	0.98	FALSE
78	The Cancer Genome Atlas	Esophageal Carcinoma	UHRF1BP1	0.19	0.20	lasso	10	0.17	5.2e-06	10.0	10.0	1.7e-23	0.59	0.02	0.98	FALSE
79	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	SNRPC	0.06	0.07	lasso	2	0.07	6.7e-08	10.0	-10.0	1.2e-23	-0.59	0.02	0.98	FALSE
80	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	UHRF1BP1	0.06	0.06	enet	8	0.06	1.3e-07	9.9	9.2	3.7e-20	0.35	0.02	0.98	FALSE
81	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C6orf106	0.04	0.01	blup	68	0.01	2.4e-02	10.0	7.6	4.1e-14	0.87	0.02	0.51	FALSE
82	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	UHRF1BP1	0.18	0.28	lasso	5	0.27	1.0e-30	10.0	10.1	4.7e-24	0.61	0.02	0.98	FALSE
83	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	UHRF1BP1	0.08	0.09	blup	71	0.10	2.0e-06	10.0	10.5	1.4e-25	0.59	0.02	0.98	FALSE
84	The Cancer Genome Atlas	Brain Lower Grade Glioma	C6orf106	0.04	0.05	lasso	4	0.03	8.1e-05	10.0	9.9	5.7e-23	0.98	0.03	0.97	FALSE
85	The Cancer Genome Atlas	Brain Lower Grade Glioma	UHRF1BP1	0.06	0.05	blup	70	0.04	8.6e-06	5.5	8.2	1.6e-16	0.19	0.05	0.95	FALSE
86	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	UHRF1BP1	0.12	0.09	blup	70	0.06	5.6e-04	10.0	8.0	8.7e-16	0.58	0.02	0.94	FALSE
87	The Cancer Genome Atlas	Lung Adenocarcinoma	C6orf106	0.03	0.03	lasso	3	0.01	7.6e-03	6.1	7.9	3.0e-15	0.80	0.04	0.72	FALSE
88	The Cancer Genome Atlas	Lung Adenocarcinoma	FKBP5	0.04	0.05	lasso	2	0.04	5.4e-05	5.4	5.7	1.6e-08	0.10	0.08	0.86	FALSE
89	The Cancer Genome Atlas	Lung Adenocarcinoma	UHRF1BP1	0.06	0.07	enet	20	0.08	6.4e-10	10.0	9.8	1.4e-22	0.49	0.02	0.98	FALSE
90	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	UHRF1BP1	0.04	0.06	blup	70	0.06	1.5e-07	10.0	8.0	1.3e-15	0.36	0.02	0.98	FALSE
91	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	C6orf106	0.14	0.07	enet	6	0.06	1.0e-04	10.0	6.8	1.4e-11	0.86	0.03	0.93	FALSE
92	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	UHRF1BP1	0.06	0.07	lasso	1	0.05	1.5e-04	9.9	9.9	4.3e-23	0.57	0.02	0.98	FALSE
93	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	UHRF1BP1	0.20	0.23	lasso	16	0.25	8.3e-11	10.0	10.4	3.3e-25	0.57	0.02	0.98	FALSE
94	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	UHRF1BP1	0.13	0.09	enet	13	0.10	6.4e-05	10.0	8.7	2.5e-18	0.52	0.02	0.96	FALSE
95	The Cancer Genome Atlas	Prostate Adenocarcinoma	UHRF1BP1	0.10	0.20	lasso	5	0.19	1.6e-19	10.0	9.7	2.2e-22	0.53	0.02	0.98	FALSE
96	The Cancer Genome Atlas	Soft Tissue Sarcoma	UHRF1BP1	0.08	0.09	blup	71	0.08	1.0e-05	10.0	10.4	2.8e-25	0.49	0.02	0.98	FALSE
97	The Cancer Genome Atlas	Stomach Adenocarcinoma	UHRF1BP1	0.08	0.10	lasso	1	0.10	7.1e-08	10.0	10.0	1.1e-23	0.59	0.02	0.98	FALSE
98	The Cancer Genome Atlas	Thyroid Carcinoma	SNRPC	0.05	0.05	blup	31	0.05	2.9e-05	10.0	-10.7	1.4e-26	-0.67	0.02	0.98	FALSE
99	The Cancer Genome Atlas	Thyroid Carcinoma	UHRF1BP1	0.07	0.03	blup	71	0.05	2.8e-05	10.0	7.2	5.8e-13	0.20	0.02	0.98	FALSE
100	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	SNRPC	0.09	0.11	lasso	2	0.10	8.1e-04	10.0	-10.0	1.6e-23	-0.59	0.02	0.80	FALSE