TWAS hub - MAPK13

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1260	0.0330	1.3e-08	0.094	0.064	0.069	0.069	0.082	1.8e-11	3.1e-08	7.7e-09	9.2e-09	3.0e-10
2	GTEx	Brain Cerebellum	0.4240	0.0770	3.9e-07	0.052	NA	0.314	NA	0.171	1.2e-02	NA	5.6e-10	NA	9.6e-06
3	GTEx	Brain Cortex	0.2180	0.0970	9.9e-03	0.029	NA	0.033	NA	0.048	5.5e-02	NA	4.2e-02	NA	1.9e-02
4	GTEx	Cells Transformed fibroblasts	0.1190	0.0390	1.4e-05	0.047	NA	0.053	NA	0.045	1.8e-04	NA	7.5e-05	NA	2.6e-04
5	GTEx	Colon Transverse	0.1870	0.0600	1.3e-04	0.024	NA	0.084	NA	0.060	2.5e-02	NA	8.1e-05	NA	8.0e-04
6	GTEx	Esophagus Mucosa	0.3420	0.0560	0.0e+00	0.291	NA	0.354	NA	0.376	9.6e-20	NA	1.4e-24	NA	2.3e-26
7	GTEx	Esophagus Muscularis	0.1320	0.0390	6.7e-05	0.094	NA	0.080	NA	0.070	2.4e-06	NA	1.5e-05	NA	4.8e-05
8	GTEx	Heart Atrial Appendage	0.1210	0.0590	9.8e-03	-0.002	NA	-0.004	NA	0.000	4.2e-01	NA	5.3e-01	NA	3.1e-01
9	GTEx	Ovary	0.2320	0.0880	4.6e-03	-0.012	NA	0.024	NA	-0.008	9.8e-01	NA	8.7e-02	NA	5.4e-01
10	GTEx	Pancreas	0.1970	0.0580	4.9e-05	0.138	NA	0.148	NA	0.158	2.0e-06	NA	8.2e-07	NA	3.4e-07
11	GTEx	Skin Not Sun Exposed Suprapubic	0.1970	0.0650	7.2e-05	0.053	NA	0.052	NA	0.082	7.4e-04	NA	8.1e-04	NA	2.8e-05
12	GTEx	Skin Sun Exposed Lower leg	0.2290	0.0580	3.9e-09	0.203	NA	0.231	NA	0.231	1.1e-16	NA	4.8e-19	NA	4.9e-19
13	GTEx	Testis	0.1640	0.0570	1.6e-03	0.161	NA	0.098	NA	0.162	1.2e-07	NA	4.1e-05	NA	1.1e-07
14	ROSMAP	Brain Pre-frontal Cortex	0.0656	0.0256	1.6e-03	0.002	0.026	0.001	NA	0.003	1.6e-01	2.5e-04	2.5e-01	NA	1.0e-01
15	TCGA	Breast Invasive Carcinoma	0.0187	0.0119	4.3e-03	0.018	0.007	0.009	NA	0.012	1.0e-04	1.3e-02	4.3e-03	NA	1.1e-03
16	TCGA	Cervical Squamous Cell Carcinoma	0.0990	0.0520	1.5e-03	0.022	0.038	0.035	NA	0.029	2.8e-02	5.7e-03	8.0e-03	NA	1.5e-02
17	TCGA	Colon Adenocarcinoma	0.1250	0.0520	5.4e-06	0.066	0.088	0.068	NA	0.070	1.2e-04	8.5e-06	8.7e-05	NA	7.4e-05
18	TCGA	Esophageal Carcinoma	0.1390	0.0650	4.3e-03	0.124	0.060	0.060	NA	0.101	9.8e-05	5.6e-03	5.6e-03	NA	4.2e-04
19	TCGA	Head and Neck Squamous Cell Carcinoma	0.0402	0.0203	1.1e-03	0.047	0.022	0.041	NA	0.040	5.2e-06	1.4e-03	2.1e-05	NA	2.2e-05
20	TCGA	Brain Lower Grade Glioma	0.0446	0.0198	2.8e-04	0.018	0.036	0.030	NA	0.020	3.7e-03	5.7e-05	2.0e-04	NA	2.2e-03
21	TCGA	Lung Adenocarcinoma	0.0247	0.0136	5.7e-03	0.017	0.010	0.013	NA	0.011	3.6e-03	2.3e-02	9.7e-03	NA	1.6e-02
22	TCGA	Lung Squamous Cell Carcinoma	0.0640	0.0289	1.6e-05	0.020	0.016	0.020	NA	0.019	2.1e-03	5.0e-03	2.1e-03	NA	2.7e-03
23	TCGA	Stomach Adenocarcinoma	0.0700	0.0310	1.2e-04	0.078	0.054	0.049	NA	0.061	2.6e-06	9.3e-05	1.9e-04	NA	3.1e-05
24	TCGA	Thyroid Carcinoma	0.0660	0.0310	4.4e-06	0.065	0.055	0.050	NA	0.061	6.7e-07	4.4e-06	1.2e-05	NA	1.4e-06

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24
Ever had bowel cancer screening	6.2	7.3	14.7	-3.2	2.4	-1.6	-2.0	2.6	3.4	2.7	1.1	2.5	3.0	3.5	3.3	2.6	-1.3	2.9	2.9	3.8	2.4	3.1	0.2	3.1	2.2	2.3	3.4
Age started oral contraceptive pill	5.7	7.1	12.6	3.2	-2.9	1.7	2.8	-1.8	-3.3	-2.2	-2.5	-1.9	-2.7	-3.6	-3.0	-2.7	1.8	-3.2	-2.8	-3.0	-2.3	-2.9	-0.1	-3.1	-2.4	-2.5	-3.4
Blood Red Count	5.4	52.4	83.5	8.3	-3.0	6.1	7.5	-8.2	-9.0	-1.9	2.5	-5.6	-8.2	-9.1	-8.9	-8.4	3.7	-8.2	-8.9	-8.3	-6.8	-8.0	2.0	-8.4	-7.2	-7.3	-9.0
Glaucoma (self-reported)	4.1	4.8	8.9	-2.7	-1.0	-2.7	-1.6	2.5	2.4	0.2	-1.5	1.5	1.6	1.9	2.7	2.2	-2.3	0.5	2.7	2.7	2.8	3.0	-0.9	2.8	2.4	2.2	2.5
Heart attack	3.8	4.9	8.2	-2.7	0.6	-1.9	-2.3	2.2	2.7	0.3	-2.4	1.4	2.1	2.9	2.7	2.2	-2.7	2.3	2.1	2.6	1.6	2.7	-0.2	2.6	2.2	1.9	2.9
Heart attack/myocardial infarction (self-reported)	3.5	4.5	7.4	-2.6	0.3	-2.0	-2.3	2.4	2.5	0.0	-2.6	1.4	2.0	2.7	2.5	2.0	-2.6	2.2	2.0	2.4	1.5	2.6	-0.4	2.4	2.1	1.7	2.7
Sitting height	3.1	22.0	45.0	-5.0	3.2	-2.1	-5.1	3.8	5.8	5.2	2.2	6.7	5.8	6.7	5.4	5.2	-0.4	6.0	4.5	5.3	3.1	4.3	1.1	4.9	3.5	4.4	5.8
Diverticular disease/diverticulitis (self-reported)	2.8	3.4	7.0	1.5	0.7	1.5	0.5	-1.6	-2.4	-0.0	0.6	-1.0	-2.4	-2.5	-2.5	-2.6	1.1	-1.8	-1.9	-2.2	-1.9	-2.0	1.6	-2.0	-1.8	-2.5	-2.0
Birth weight	2.8	6.1	24.7	-1.4	4.8	0.9	-2.5	0.3	2.2	3.4	5.0	3.9	2.6	2.7	1.7	1.4	0.7	3.4	0.9	3.0	-0.5	1.1	2.6	1.3	-0.0	0.4	2.5
Loneliness, isolation	2.8	3.9	16.8	-1.0	2.7	-0.5	-2.0	2.1	1.9	4.1	0.8	2.4	3.0	2.1	2.0	2.4	1.2	2.2	1.6	2.3	0.5	0.6	1.7	0.9	-0.6	1.6	1.9
Heel bone mineral density (BMD) T-score, automated (right)	2.7	6.3	12.7	2.7	-1.4	1.1	3.5	-3.3	-3.1	-1.0	0.5	-2.3	-3.2	-3.0	-3.1	-2.5	2.3	-2.8	-3.0	-2.5	-1.3	-2.3	-0.0	-2.9	-2.9	-1.4	-3.6
Heart disease (siblings)	2.7	3.3	10.1	-2.4	1.6	-3.2	-1.2	1.1	1.8	1.8	-0.1	2.1	1.3	1.5	2.2	1.6	-0.9	0.3	2.0	2.4	1.7	2.3	1.0	2.2	1.3	1.7	2.3
Height	2.6	49.2	151.3	-6.5	9.0	-1.0	-8.9	5.1	8.0	9.0	4.8	12.3	8.9	9.5	7.0	6.8	1.4	10.0	6.0	6.0	2.7	5.0	3.9	6.0	4.6	4.5	8.2
Medication: Aspirin	2.6	3.4	7.2	-1.6	1.0	-0.9	-2.5	2.5	2.1	1.7	-0.9	2.4	2.5	2.3	2.2	2.0	-0.9	2.7	2.2	2.4	0.9	1.2	0.7	1.7	0.9	1.1	2.3
Relative age voice broke	2.5	3.9	7.3	1.8	-1.0	2.5	2.5	-2.3	-2.4	-1.9	-1.3	-1.3	-2.2	-2.6	-2.2	-2.0	1.0	-2.3	-2.1	-2.7	-1.6	-1.9	0.2	-2.0	-1.3	-1.9	-2.1
Medication: Omeprazole	2.5	3.0	6.0	-2.1	0.5	-1.9	-2.3	1.9	1.8	1.9	1.3	2.4	1.9	1.7	2.0	1.5	-0.1	1.5	2.1	2.4	1.2	1.7	1.2	1.8	0.7	1.1	2.2
Alcohol drinker status: Never	2.5	3.1	7.5	2.4	-0.1	2.3	0.9	-0.8	-2.0	-1.1	-1.3	-0.7	-1.4	-1.5	-2.3	-1.8	1.2	-0.5	-2.3	-2.7	-1.9	-2.6	-0.6	-2.2	-1.2	-1.7	-2.5
Diabetes (self-reported)	2.4	3.8	11.0	-1.2	1.0	-0.5	-2.2	2.7	2.3	2.1	2.0	1.1	3.3	2.4	2.2	2.6	1.4	3.2	2.4	1.7	1.0	0.8	-0.4	1.5	1.3	1.5	1.9
Mouth/teeth dental problems: Loose teeth	2.4	2.8	6.6	-1.9	0.6	-1.8	-0.8	1.6	1.8	1.5	-0.3	1.4	2.0	1.6	2.0	2.5	1.2	1.0	2.6	1.8	2.3	1.3	-0.6	1.7	0.9	2.5	1.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.4	2.9	5.3	-1.5	0.8	-1.2	-1.4	1.4	2.2	1.1	0.8	0.1	2.3	2.1	2.3	2.3	-1.3	1.5	2.1	2.2	1.6	1.8	-1.0	1.9	1.5	2.2	1.8
Medication: Aspirin	2.4	3.2	7.8	-1.4	1.0	-1.1	-2.2	2.3	2.1	1.8	-1.1	2.0	2.6	2.1	2.2	2.1	-0.1	2.8	2.1	2.5	0.8	1.1	0.8	1.5	0.6	1.1	2.2
Risk taking	2.4	3.5	8.2	-2.0	2.5	-0.4	-1.2	1.1	2.2	1.9	2.1	2.0	2.2	2.4	2.0	2.1	-0.2	2.5	2.0	2.9	1.2	1.6	0.7	1.9	0.8	1.9	2.3
Bilateral oophorectomy (both ovaries removed)	2.3	2.7	9.8	1.5	1.1	0.1	-0.2	-1.3	-1.8	1.4	-0.1	0.8	-1.7	-1.8	-1.6	-2.2	-0.4	-1.6	-2.2	-0.9	-2.4	-1.3	3.1	-1.6	-2.0	-2.4	-1.2
Had menopause	2.2	2.8	7.5	2.1	-1.0	-0.1	0.6	-0.7	-2.2	-0.5	-2.3	-0.3	-1.5	-2.7	-1.7	-1.6	1.2	-2.7	-1.6	-1.7	-1.3	-1.9	0.7	-1.9	-1.8	-1.6	-2.2
Number of full sisters	2.2	2.7	9.1	-1.6	2.2	-1.6	-0.2	0.8	1.7	1.2	3.0	1.4	1.7	1.7	1.6	1.9	1.0	1.7	2.0	1.7	1.6	1.1	0.2	1.8	1.6	1.7	1.7
Standing height	2.1	20.9	64.8	-4.2	6.0	-0.4	-4.6	2.3	5.2	6.5	4.2	8.1	5.5	6.5	4.5	4.4	0.5	6.7	3.3	4.5	1.6	3.4	2.9	3.9	2.5	3.1	5.3
Seen doctor (GP) for nerves, anxiety, tension or depression	2.1	3.2	5.4	2.3	-0.5	1.9	1.1	-1.7	-2.2	-0.1	0.3	-1.3	-1.8	-2.2	-2.1	-2.1	1.7	-1.7	-2.0	-1.8	-2.0	-2.1	0.9	-2.1	-2.2	-1.9	-2.2
Exposure to tobacco smoke outside home	2.1	2.8	6.4	-2.2	0.6	-2.5	-0.8	1.3	1.9	1.7	0.8	1.8	1.2	1.8	1.7	1.8	-1.7	0.7	1.6	2.2	2.2	1.8	-0.3	2.0	1.6	2.0	1.7
Medication: Amlodipine	2.0	2.8	6.0	-1.9	-0.4	-2.5	-0.7	0.5	1.9	0.0	-1.4	1.5	1.3	1.6	2.2	1.9	-1.6	0.5	1.9	1.5	2.3	2.0	-1.4	2.1	1.9	2.0	1.9
Illnesses of father: High blood pressure	2.0	2.5	5.4	2.3	-0.6	0.4	1.3	-1.9	-1.9	-1.0	0.3	-1.7	-1.2	-1.7	-1.9	-1.5	0.8	-1.0	-1.9	-2.2	-1.5	-2.3	-0.2	-2.2	-1.7	-1.5	-2.1
Irritable Bowel Disease (IBD)	1.9	4.5	11.3	-2.8	-0.7	-1.8	-0.5	1.3	2.3	0.5	-3.4	1.4	0.9	2.2	2.3	2.1	-2.7	0.5	2.2	2.6	3.2	2.8	-1.6	2.5	1.8	3.0	1.9
Seen a psychiatrist for nerves, anxiety, tension or depression	1.9	2.4	5.6	1.6	0.4	1.1	0.1	-0.8	-1.9	0.2	-1.0	0.1	-2.0	-1.9	-1.9	-2.3	0.1	-1.9	-1.9	-1.3	-2.1	-1.6	1.7	-1.6	-1.6	-2.4	-1.5
Financial situation satisfaction	1.9	2.3	8.3	2.1	0.3	2.9	0.5	-0.9	-1.7	1.0	-0.4	-0.8	-1.0	-1.5	-1.7	-1.3	1.3	-1.1	-1.6	-1.7	-1.5	-2.2	1.0	-2.0	-2.0	-1.3	-1.9
Fasting Glucose	1.8	2.1	4.1	2.0	-1.2	0.7	1.5	-0.8	-1.9	-1.3	0.2	-0.3	-1.7	-1.5	-1.9	-1.9	0.7	-1.3	-1.8	-1.2	-1.9	-1.5	0.2	-1.6	-1.2	-1.9	-1.9
Blood Eosinophil Count	1.8	13.9	43.5	-3.7	-1.5	-4.9	-3.5	3.9	4.0	-0.5	-6.6	1.2	3.0	3.9	4.3	4.1	-3.8	1.5	4.7	3.3	4.5	4.1	-2.2	3.7	2.7	4.6	3.3
Medication: Metformin	1.8	2.5	7.4	-0.9	1.1	-0.7	-1.5	2.0	1.8	1.5	2.7	0.7	2.7	1.7	1.8	2.3	1.9	2.0	2.0	0.9	1.2	0.5	-0.6	1.2	1.1	1.4	1.4
Mean time to correctly identify matches	1.8	3.4	11.0	1.7	-1.0	1.7	3.3	-2.6	-2.2	-1.0	-1.5	-2.7	-2.4	-2.6	-1.9	-1.8	-0.7	-2.8	-1.6	-1.5	-0.5	-1.3	-0.2	-1.3	-0.7	-1.2	-2.2
Chest pain or discomfort	1.8	2.6	7.1	1.9	-1.1	1.2	1.8	-1.3	-2.2	-1.0	-1.1	-1.1	-1.8	-2.4	-1.8	-1.4	0.1	-2.7	-1.3	-2.0	-0.8	-1.9	-0.4	-1.8	-1.4	-1.1	-2.3
Diabetes diagnosed by doctor	1.8	3.0	9.1	-0.8	1.2	0.0	-2.1	2.4	1.9	2.4	2.2	1.2	3.0	2.1	1.8	2.3	1.7	2.9	1.9	1.3	0.6	0.3	-0.1	1.1	0.7	1.2	1.5
Eye problems/disorders: Glaucoma	1.8	2.1	6.6	-1.8	-2.0	-2.6	-1.1	1.6	1.0	-1.0	-1.4	0.8	0.1	0.6	1.3	0.7	-2.1	-0.5	1.8	1.1	1.8	2.1	-1.1	1.6	1.7	1.0	1.2
Rheumatoid Arthritis	1.7	2.4	5.7	-1.8	0.7	-1.7	-2.1	2.4	1.6	0.6	-1.8	0.6	1.5	1.8	1.6	1.5	0.1	2.1	1.7	0.9	1.5	1.6	-0.6	1.6	1.6	1.3	1.8
Lung FVC	1.7	8.9	24.1	3.3	1.1	2.7	1.7	-4.0	-3.0	1.3	4.9	-0.1	-2.2	-2.9	-3.2	-3.2	1.7	-1.6	-3.3	-2.2	-3.8	-3.4	3.2	-3.5	-3.8	-3.6	-2.8
Eye problems/disorders: None of the above	1.7	2.0	6.6	1.2	2.5	2.6	0.0	-1.3	-1.1	1.0	1.8	-0.5	-0.7	-0.9	-1.3	-1.2	1.6	0.4	-1.5	-1.4	-1.8	-1.6	1.7	-1.3	-1.1	-1.3	-0.8
Medication: Lisinopril	1.7	2.2	4.2	-1.9	-0.2	-2.0	-0.3	1.5	1.8	1.0	0.2	1.2	1.6	1.7	1.9	1.8	0.1	1.1	1.9	1.9	1.6	1.9	-0.5	1.8	1.3	1.7	1.8
Waist Hip Ratio (WHR)	1.6	7.4	15.7	-2.9	1.4	-0.0	-4.0	2.0	3.4	2.8	1.7	3.4	3.3	3.8	3.2	3.3	0.1	3.5	3.0	2.9	2.1	2.6	-0.6	2.6	1.7	2.9	3.0
Number of treatments/medications taken	1.6	2.9	6.6	-1.9	0.7	-1.7	-2.3	2.6	2.0	1.5	-1.4	1.4	1.9	2.0	2.0	1.5	0.0	2.0	1.9	1.9	0.9	1.6	0.3	1.9	1.4	1.0	2.2
Medication: Atenolol	1.6	1.9	4.7	-1.1	1.4	-1.1	-2.0	1.6	1.2	1.9	-2.1	2.0	1.3	0.9	1.4	1.2	-1.5	0.5	1.2	2.2	0.4	0.8	1.8	0.9	-0.2	0.6	1.4
Alcohol intake versus 10 years previously	1.6	2.4	4.4	-1.7	1.2	-1.3	-1.1	1.8	1.8	1.3	-1.9	0.6	1.5	1.8	1.9	2.1	-0.9	0.8	1.7	1.7	2.1	1.7	-0.7	1.6	1.2	2.1	1.5
Medication for pain relief, constipation, heartburn	1.6	2.8	13.5	1.2	-1.3	0.0	3.7	-3.3	-1.5	-2.5	1.1	-2.1	-2.1	-1.7	-1.4	-1.3	-0.5	-1.8	-1.4	-1.2	-0.2	-0.4	-1.5	-0.8	0.1	-0.4	-1.8
Cholesterol lowering medication	1.6	2.3	6.6	-1.3	1.3	-0.6	-2.0	1.7	1.5	2.6	1.2	2.2	2.0	1.4	1.6	1.7	0.0	1.6	1.7	2.3	0.9	0.7	1.0	1.2	0.1	1.2	1.5
Number of incorrect matches in round	1.5	2.5	5.0	1.2	-1.3	0.0	1.9	-0.8	-1.9	-1.5	-2.2	-1.9	-2.2	-2.0	-1.9	-1.9	1.0	-2.1	-1.6	-1.7	-1.2	-1.1	0.3	-1.5	-0.9	-1.5	-1.8
Forced expiratory volume in 1-second (FEV1), Best measure	1.5	4.8	28.2	1.0	3.6	2.4	-0.7	-2.5	-0.6	3.3	5.3	3.2	-0.1	0.2	-1.2	-1.3	0.8	1.0	-1.7	-0.6	-2.5	-1.4	3.4	-1.5	-2.2	-1.9	-0.5
Number of self-reported non-cancer illnesses	1.5	2.7	6.0	-1.5	-1.4	-2.4	-0.5	2.4	1.6	-0.7	-1.9	-0.2	1.1	1.5	1.7	1.6	-0.5	1.0	2.1	1.2	1.9	1.9	-2.4	1.8	2.1	1.8	1.3
Average weekly champagne plus white wine intake	1.5	2.0	4.1	-1.4	-2.0	-2.0	-0.7	1.1	1.6	-0.2	-1.7	-0.2	1.0	1.8	1.4	1.5	-1.6	1.3	1.4	1.6	1.8	1.6	-1.4	1.2	1.0	1.7	1.0
Myopia	1.5	2.2	7.1	-1.6	0.4	-0.9	-1.2	1.1	1.9	0.4	1.0	0.6	1.5	1.7	1.8	1.5	-2.7	1.4	1.6	1.4	1.6	1.6	-0.7	1.8	1.8	1.2	2.0
Trunk fat percentage	1.4	5.5	42.2	-2.2	-0.7	-2.0	-1.3	4.7	1.6	-0.6	-6.5	0.8	1.3	1.4	2.0	1.6	-1.9	-0.5	2.3	1.1	2.1	2.2	-1.4	2.5	3.0	1.5	1.9
Heel bone mineral density (BMD) T-score, automated (left)	1.4	3.2	6.2	1.7	-0.8	0.8	2.5	-2.3	-2.2	-0.4	0.7	-2.0	-2.2	-2.0	-2.1	-1.5	1.9	-2.0	-2.3	-1.7	-0.8	-1.6	-0.1	-2.1	-2.3	-0.7	-2.5
Leg predicted mass (left)	1.4	7.2	14.7	-2.8	2.9	-0.6	-1.3	2.6	3.1	3.1	1.0	3.8	3.3	3.7	2.9	3.4	1.1	2.9	2.9	2.7	2.4	2.1	-0.2	2.8	2.4	3.1	2.9
Trunk fat mass	1.4	5.9	22.8	-2.6	0.7	-1.5	-1.6	4.5	2.3	0.7	-4.8	2.1	2.2	2.4	2.5	2.4	-1.1	0.6	2.6	1.8	2.3	2.4	-1.1	2.9	3.2	2.1	2.4
Trunk fat-free mass	1.4	7.8	28.1	-1.8	4.4	1.0	-1.5	0.9	2.7	4.8	4.1	5.3	3.4	3.6	2.3	2.9	1.7	3.7	1.8	2.6	1.3	1.2	1.0	1.8	1.0	2.4	2.4
Time employed in main current job	1.4	1.6	5.8	0.9	-2.2	-0.1	1.6	-0.7	-1.3	-2.4	-1.9	-1.3	-1.3	-1.4	-1.0	-0.9	-0.9	-1.7	-0.8	-1.3	-0.2	-0.4	-1.6	-0.7	0.4	-0.3	-1.4
Serious illness, injury or assault of a close relative in last 2 years	1.4	1.6	4.9	0.9	0.7	1.6	0.9	-0.9	-1.4	0.4	2.2	0.3	-1.5	-1.4	-1.4	-1.6	0.9	-1.4	-1.3	-0.8	-1.3	-1.1	1.6	-0.9	-1.0	-1.5	-1.1
Mouth/teeth dental problems: Dentures	1.4	2.3	4.7	1.8	0.3	1.6	0.3	-1.2	-1.7	0.4	-0.3	-0.3	-1.3	-1.6	-1.8	-1.9	1.6	-1.1	-2.0	-1.8	-1.9	-1.8	1.1	-2.0	-2.0	-2.2	-1.6
Forced vital capacity (FVC), Best measure	1.4	5.1	34.2	0.9	3.6	2.4	-0.7	-2.2	-0.5	3.6	5.8	3.1	-0.1	0.3	-1.2	-1.4	0.8	1.3	-1.9	-0.7	-2.8	-1.3	3.4	-1.4	-1.9	-2.1	-0.2
Long-standing illness, disability or infirmity	1.4	2.1	5.7	-0.7	0.4	-0.3	-2.1	2.0	1.7	1.9	-0.1	2.2	2.4	2.1	1.5	1.7	1.0	2.4	1.2	1.5	0.3	0.6	0.1	0.8	0.1	1.1	1.1
Breast cancer (self-reported)	1.4	1.6	3.0	-1.1	-1.7	-1.5	-0.7	1.5	1.3	-0.8	-1.1	-0.5	1.2	1.3	1.4	1.6	-0.5	0.7	1.3	1.1	1.6	1.4	-1.6	1.2	1.4	1.7	1.0
Medication: Omeprazole (e.g. Zanprol)	1.4	1.7	4.5	-1.5	0.0	-1.1	-1.7	1.8	1.4	1.8	0.4	1.4	1.5	1.3	1.5	1.3	-0.2	1.2	1.6	2.1	0.9	1.2	1.1	1.1	0.1	0.9	1.5
Leg fat-free mass (left)	1.3	7.0	14.5	-2.7	2.9	-0.6	-1.4	2.6	3.0	3.0	0.9	3.8	3.3	3.6	2.9	3.3	1.0	2.9	2.9	2.7	2.4	2.1	-0.2	2.8	2.4	3.1	2.9
Townsend deprivation index at recruitment	1.3	1.9	9.0	-1.3	3.0	0.4	-1.1	1.1	1.2	2.2	1.8	1.1	1.4	1.6	1.0	1.4	1.6	1.6	1.0	0.8	1.1	0.5	0.0	1.0	0.3	1.5	1.2
Fed-up feelings	1.3	2.4	6.1	-1.1	1.5	-0.7	-1.4	1.8	1.9	1.8	0.5	1.6	2.5	2.0	1.9	2.1	1.3	1.7	1.7	1.7	1.0	1.1	-0.3	1.4	0.8	1.8	1.7
Trunk predicted mass	1.3	7.3	27.2	-1.7	4.2	1.1	-1.4	0.8	2.5	4.8	4.0	5.2	3.3	3.5	2.1	2.8	1.6	3.5	1.7	2.6	1.2	1.1	1.0	1.7	0.9	2.3	2.2
Number of full brothers	1.3	1.6	4.5	-1.7	1.5	-2.1	-0.5	0.8	1.1	1.7	1.6	1.5	0.8	1.1	1.1	1.0	-0.2	0.6	1.0	1.4	1.3	1.3	0.5	1.6	1.1	1.2	1.4
Forced expiratory volume in 1-second (FEV1), predicted	1.3	2.8	15.4	-1.0	3.1	-0.0	-2.0	-0.0	1.4	2.4	3.0	3.9	1.3	1.9	1.0	0.6	0.5	1.9	0.6	1.0	-0.1	0.7	1.9	1.0	0.5	0.4	1.6
Whole body fat-free mass	1.3	7.3	23.9	-2.2	4.0	0.4	-1.5	1.7	2.8	4.3	2.8	4.9	3.4	3.6	2.5	3.0	1.6	3.3	2.2	2.6	1.6	1.5	0.7	2.2	1.5	2.6	2.6
Leg fat-free mass (right)	1.3	7.0	14.2	-2.8	3.0	-0.7	-1.2	2.7	3.0	3.2	1.1	3.8	3.2	3.6	2.9	3.3	1.1	2.8	2.9	2.8	2.4	2.1	-0.0	2.8	2.3	3.0	2.9
Whole body water mass	1.3	7.5	24.1	-2.2	4.0	0.3	-1.5	1.8	2.8	4.4	2.9	4.9	3.4	3.6	2.5	3.1	1.5	3.3	2.3	2.8	1.7	1.6	0.8	2.3	1.5	2.6	2.6
Leg predicted mass (right)	1.3	7.2	13.8	-2.8	3.0	-0.8	-1.2	2.7	3.0	3.2	1.1	3.7	3.3	3.6	2.9	3.4	1.2	2.8	3.0	2.8	2.5	2.1	-0.0	2.9	2.3	3.1	2.9
Basal metabolic rate	1.3	7.1	21.4	-2.3	3.6	0.1	-1.6	2.3	2.9	3.9	1.7	4.6	3.4	3.6	2.6	3.2	1.1	3.1	2.4	2.6	1.9	1.7	0.3	2.4	1.8	2.7	2.7
Type 2 Diabetes (T2D) (2018)	1.2	2.2	6.2	-0.2	2.2	0.7	-2.5	1.9	1.3	2.1	1.7	2.0	2.5	1.6	1.2	1.4	1.6	2.5	1.3	0.5	-0.3	-0.2	0.5	0.6	0.3	0.2	1.3
Ever had hysterectomy (womb removed)	1.2	1.4	3.4	1.2	0.3	-0.4	1.1	-1.7	-1.5	0.7	-1.1	0.2	-1.6	-1.5	-1.3	-1.2	0.7	-1.9	-1.1	-0.3	-0.7	-1.0	1.5	-1.1	-1.6	-0.6	-1.5
Vitamin and mineral supplements	1.2	1.6	8.6	0.8	0.5	0.1	1.3	-1.0	-1.8	-0.3	-0.1	-0.1	-1.7	-2.2	-1.3	-1.5	-0.1	-2.9	-1.2	-1.0	-1.0	-0.9	1.6	-1.0	-1.1	-1.3	-1.2
Maternal smoking around birth	1.2	1.8	7.8	-1.6	2.8	-0.8	-0.6	0.5	1.2	1.9	1.5	1.4	1.2	1.0	1.3	1.2	1.4	0.8	1.4	1.5	0.7	0.7	1.4	1.3	0.6	0.9	1.8
Chronic bronchitis/emphysema (father)	1.2	1.4	5.1	-1.3	2.3	-2.0	-0.6	1.8	1.0	1.5	0.1	1.2	1.1	1.0	1.1	1.1	0.6	0.3	1.3	1.4	0.9	0.9	0.8	1.0	0.4	0.9	1.2
Ever unenthusiastic/disinterested for a whole week	1.2	1.5	3.7	1.6	-0.7	1.0	1.5	-1.9	-1.5	-0.4	-0.1	-0.7	-1.3	-1.5	-1.5	-1.3	-0.1	-1.1	-1.3	-1.5	-1.0	-1.0	-0.1	-1.3	-0.9	-1.1	-1.7
Medication: Cholesterol lowering	1.2	1.8	5.9	-1.3	1.1	-1.4	-1.3	2.4	1.6	1.2	-0.5	1.4	1.8	1.6	1.6	1.6	0.8	1.7	1.8	1.3	0.9	0.7	0.4	1.1	0.6	0.9	1.5
Birth weight of first child	1.2	2.1	19.8	-0.9	2.0	0.5	0.8	-1.0	1.1	1.9	4.4	1.2	0.8	1.1	1.0	1.2	0.8	0.6	0.6	2.0	1.2	1.1	0.2	1.4	0.9	1.5	0.9
Medication for cholesterol, blood pressure or diabetes	1.2	2.1	6.5	1.4	-0.6	1.5	1.5	-2.6	-1.7	-0.7	1.0	-1.0	-1.9	-1.6	-1.8	-1.8	-0.7	-1.4	-2.1	-0.9	-1.3	-1.0	0.5	-1.3	-1.1	-1.2	-1.6
Heart disease (mother)	1.2	1.5	4.1	-1.1	1.7	0.3	-1.3	1.6	1.3	1.6	-0.9	2.0	1.7	1.3	1.3	1.3	-0.0	0.9	1.3	1.6	0.4	0.6	1.1	0.9	-0.0	0.7	1.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.2	2.5	6.7	1.9	1.5	2.3	-0.2	-1.5	-1.1	1.8	2.6	1.2	-0.3	-0.7	-1.4	-1.3	1.1	0.5	-1.4	-0.9	-2.2	-1.9	2.0	-1.8	-2.3	-1.8	-1.2
Diastolic blood pressure, automated reading	1.2	3.6	8.9	1.8	-0.7	1.1	1.4	-0.2	-2.6	-0.7	-1.8	-1.5	-2.7	-3.0	-2.4	-2.7	-0.6	-2.8	-2.1	-2.0	-2.0	-1.6	0.6	-1.7	-1.0	-2.6	-2.1
Pack years of smoking	1.2	1.8	4.3	-1.6	1.9	-0.4	0.0	0.8	1.5	1.9	0.0	-0.2	1.2	1.8	1.4	1.6	2.1	1.4	1.3	1.1	1.4	1.2	-0.2	1.3	0.8	1.8	1.4
Ulcerative Colitis (UC)	1.1	2.1	5.9	-1.7	-1.0	-0.9	-0.7	0.5	1.7	0.6	-2.1	1.4	0.8	1.7	1.6	1.5	-2.4	0.4	1.3	1.9	2.1	1.7	-0.5	1.5	0.6	2.1	1.2
Mean Putamen Volume	1.1	1.3	3.6	-1.4	-0.9	-1.0	-1.3	0.2	1.1	-0.1	0.0	-0.1	0.9	0.9	1.4	1.7	-1.3	0.4	1.5	1.3	1.7	1.2	-0.9	1.3	1.1	1.9	0.9
Supplements: Zinc	1.1	1.2	3.2	-1.3	0.1	-1.4	-0.1	0.4	1.1	0.5	1.8	-0.2	0.9	1.1	1.1	1.1	1.6	1.4	1.4	1.2	1.4	1.3	-0.8	1.2	0.9	1.2	1.1
Severe depression (siblings)	1.1	1.3	5.4	1.0	1.1	2.3	-0.2	-0.1	-1.0	1.5	0.0	0.0	-0.4	-1.0	-1.0	-0.7	1.1	-0.4	-0.7	-0.8	-1.2	-1.7	2.0	-1.3	-1.8	-0.9	-0.8
Forced vital capacity (FVC)	1.1	4.3	25.6	1.3	2.1	2.3	0.1	-2.5	-0.9	2.9	5.1	2.7	-0.6	-0.2	-1.5	-1.7	0.1	0.6	-2.1	-0.8	-2.8	-1.4	3.2	-1.6	-2.1	-2.1	-0.7
Medication: Simvastatin	1.1	1.6	6.6	-0.0	1.4	0.0	-1.2	1.6	0.8	2.6	1.5	1.5	2.0	0.9	0.7	1.1	2.3	1.8	0.7	0.9	-0.1	-0.7	1.5	-0.2	-1.1	-0.0	0.6
Neuroticism score	1.1	2.3	4.5	-1.9	1.4	-2.0	-1.2	1.1	1.9	1.5	0.0	0.8	1.8	1.6	2.0	1.6	0.4	1.4	1.8	1.8	1.4	1.9	0.1	1.8	1.2	1.4	2.1
Forced expiratory volume in 1-second (FEV1)	1.1	3.9	24.9	0.9	2.4	2.0	-0.4	-2.4	-0.5	3.0	5.0	3.2	-0.2	0.3	-1.1	-1.2	0.0	1.0	-1.6	-0.3	-2.2	-1.1	3.2	-1.4	-2.1	-1.7	-0.4
Pulse rate	1.1	1.9	5.9	1.4	-0.0	1.0	-1.9	1.1	-0.9	1.6	0.3	1.7	-0.0	-0.4	-1.0	-1.0	2.4	0.4	-1.1	-0.4	-2.3	-1.6	1.8	-1.6	-2.2	-1.7	-0.9
Arm fat percentage (left)	1.1	4.4	30.9	-1.6	-1.0	-1.6	-0.7	4.1	1.3	-1.4	-5.6	0.1	1.1	1.1	1.6	1.5	-2.0	-0.5	2.1	0.7	2.0	1.8	-2.4	2.1	3.0	1.5	1.4
Tinnitus: Yes, now most or all of the time	1.1	1.3	4.0	-1.4	0.9	-1.3	-0.8	-0.2	1.2	0.6	2.0	1.7	0.4	1.0	1.1	0.7	-1.2	0.4	1.0	1.7	1.2	1.5	0.0	1.6	1.3	0.8	1.3
Basal cell carcinoma (self-reported)	1.1	1.3	5.6	-0.6	1.5	0.3	-1.2	0.9	0.8	2.0	1.6	2.4	1.4	0.7	1.0	1.1	0.8	0.3	0.9	1.6	0.5	0.4	1.5	0.5	-0.5	0.6	1.0
Reaction Time	1.0	1.9	7.5	0.3	-0.9	0.1	2.7	-2.6	-1.3	-0.7	-1.3	-2.0	-2.2	-1.6	-1.1	-1.2	-1.8	-2.5	-1.0	-0.3	0.4	0.1	-0.2	-0.3	-0.0	-0.2	-1.2
Primary Biliary Cirrhosis	1.0	1.4	3.0	-1.5	1.6	0.5	-1.7	1.7	1.2	1.3	0.3	0.7	0.7	1.5	1.0	0.8	-1.1	1.4	1.0	1.3	0.7	1.2	0.2	1.5	1.4	1.0	1.3
Medication: Levothyroxine sodium	1.0	1.7	6.2	1.4	-1.4	0.3	1.8	-0.5	-1.5	-1.1	-2.5	-0.9	-1.7	-1.0	-1.6	-1.5	0.1	-1.4	-1.5	-1.2	-0.9	-0.9	-0.4	-1.3	-1.1	-0.7	-1.8
Financial difficulties in last 2 years	1.0	1.4	6.4	-0.1	2.1	1.6	-0.9	1.1	1.0	2.5	-0.1	1.5	1.7	1.3	0.9	1.5	0.7	1.1	0.7	1.0	0.6	-0.2	0.6	0.2	-0.9	1.3	0.6
Weight	1.0	5.0	12.7	-2.2	1.9	-0.5	-1.5	3.6	2.4	2.4	-1.7	3.4	2.8	3.0	2.4	2.6	0.0	1.8	2.2	2.1	1.9	1.8	-0.4	2.4	2.3	2.3	2.3
Body fat percentage	1.0	4.1	41.1	-1.5	-1.0	-1.6	-0.8	4.2	1.0	-0.8	-6.4	0.4	0.8	0.8	1.4	1.1	-1.7	-0.9	1.7	0.5	1.7	1.5	-1.7	1.8	2.6	1.1	1.1
Medication: Blood pressure	1.0	1.8	3.3	-1.6	0.7	-1.8	-1.5	1.8	1.5	0.4	-1.2	1.3	1.2	1.3	1.6	1.3	0.5	0.9	1.7	0.6	1.4	1.3	-0.6	1.6	1.6	1.2	1.6
Comparative height size at age 10	1.0	5.6	24.8	-0.9	4.2	1.8	-2.5	0.6	2.2	3.8	1.6	5.0	3.1	3.1	1.7	1.9	0.7	3.8	0.7	1.9	-0.6	0.5	2.5	0.9	0.1	0.7	2.1
Handedness (chirality/laterality): Left-handed	1.0	1.2	4.3	-1.5	0.7	-0.7	-2.1	0.4	1.2	1.3	0.3	1.9	1.1	1.1	1.2	0.9	-1.3	0.9	0.8	1.0	0.8	1.1	0.6	1.0	0.6	0.6	1.5
Medication: Gliclazide	1.0	1.1	6.9	0.2	1.4	-0.0	-0.8	0.8	0.4	2.6	1.5	0.7	1.5	0.2	0.5	0.8	2.3	1.0	0.9	0.7	-0.2	-0.6	1.2	-0.0	-0.7	0.1	0.4
Medication: Bendroflumethiazide	1.0	1.6	3.4	-1.8	0.1	-1.4	-0.3	1.2	1.5	0.4	-0.3	0.8	0.7	1.3	1.4	1.1	-0.8	1.0	1.4	1.1	1.8	1.7	-1.0	1.7	1.8	1.3	1.4
Medication: Atorvastatin	1.0	1.2	5.9	-1.5	-0.0	-1.4	-1.7	0.4	0.9	0.0	0.3	1.1	0.1	0.8	1.0	0.5	-2.4	0.5	1.2	1.4	0.6	1.6	0.4	1.4	1.2	0.7	1.3
Pain experienced in last month	1.0	1.7	3.3	1.6	0.2	1.5	0.1	-1.5	-1.5	-0.4	1.4	0.2	-0.9	-1.6	-1.4	-1.3	-0.1	-1.0	-1.5	-1.7	-1.6	-1.8	1.5	-1.6	-1.3	-1.7	-1.2
Bipolar Disorder (2018)	0.9	1.5	6.1	-1.2	0.7	-0.1	-1.7	1.4	1.2	2.5	-1.6	1.0	1.0	1.3	1.2	1.1	-1.1	0.8	0.8	1.6	0.7	1.0	1.1	0.8	-0.4	1.2	1.3
Crohns Disease (2017)	0.9	1.9	7.3	-1.9	-0.6	-1.3	0.7	0.6	1.1	-0.1	-2.7	0.2	-0.1	0.9	1.2	1.0	-1.3	-0.4	1.3	1.5	2.4	2.0	-1.7	1.7	1.4	2.0	0.9
Coronary Artery Disease (CAD)	0.9	1.0	3.5	-0.3	-0.5	-1.1	-0.2	0.6	0.9	1.3	-1.7	-0.9	1.1	1.1	1.1	1.6	-0.9	0.8	0.8	1.9	1.0	1.0	-0.6	0.5	-0.3	1.4	0.5
HbA1C	0.9	1.0	7.2	-0.4	0.7	1.0	-1.9	0.9	-0.4	2.1	0.5	1.1	-0.2	-0.2	-0.5	-0.6	1.1	0.1	-0.4	0.5	0.5	-0.7	2.7	-0.2	-1.4	-0.8	-0.1
Heel T-Score	0.9	7.1	20.3	2.1	-2.6	-2.1	4.5	-3.3	-3.0	-3.6	3.0	-2.9	-3.4	-3.3	-2.5	-2.1	2.1	-3.9	-1.9	-2.6	0.1	-1.5	-1.7	-2.0	-1.1	-0.8	-3.2
Allergy or Eczema	0.9	2.4	10.8	-0.9	0.4	0.3	-2.9	3.3	1.6	2.2	0.8	1.6	2.5	2.0	1.5	1.9	0.7	2.4	1.2	0.9	0.4	0.2	0.4	0.5	-0.1	1.0	1.4
Diabetes (mother)	0.9	1.1	5.5	1.1	1.0	0.8	0.3	0.1	-0.8	1.7	1.3	0.3	-0.0	-0.7	-0.8	-0.4	2.4	-0.7	-0.5	-0.6	-0.6	-1.5	1.4	-1.1	-1.5	-0.8	-0.9
Pack years adult smoking proportion	0.9	1.3	5.2	-1.2	2.1	0.1	-0.1	0.5	1.2	2.0	0.3	-0.4	1.1	1.5	1.1	1.3	2.3	1.4	0.9	0.9	1.0	0.8	0.2	0.9	0.2	1.4	1.2
Waist circumference	0.9	3.4	10.5	-1.7	0.6	0.1	-1.2	3.2	1.9	1.6	-2.5	2.1	2.3	2.3	2.0	2.4	0.2	1.1	2.0	1.7	1.9	1.4	-1.3	1.8	1.7	2.3	1.5
Medication: Ramipril	0.9	1.2	5.2	-1.0	1.5	-2.3	0.5	0.5	0.7	-0.0	0.2	2.1	0.2	0.5	0.8	0.9	-0.3	-1.0	1.1	0.7	1.9	1.1	-0.7	1.2	1.2	1.3	0.6
Arm fat percentage (right)	0.9	3.7	27.1	-1.4	-1.0	-1.2	-0.5	4.0	1.2	-0.9	-5.2	0.0	1.1	1.0	1.5	1.4	-1.8	-0.4	1.8	0.8	1.9	1.5	-2.1	1.9	2.6	1.5	1.1
Medication: Ibuprofen (e.g. Nurofen)	0.9	1.1	4.8	0.4	1.7	0.8	-1.8	0.6	-0.4	1.3	-1.6	0.8	-0.1	-0.2	-0.6	-0.8	0.5	0.6	-1.1	-0.6	-1.5	-0.9	2.2	-1.0	-1.3	-1.2	0.0
Impedance of arm (left)	0.9	4.3	8.8	-2.4	-0.4	-2.7	-2.7	2.1	2.5	-1.0	-3.0	0.5	1.5	2.3	2.3	1.3	-2.6	2.1	2.1	1.6	1.1	2.8	-0.0	2.4	2.4	0.9	2.8
Arm fat mass (right)	0.9	3.6	15.0	-1.7	0.1	-1.0	-0.8	3.9	1.6	0.2	-3.8	1.5	1.8	1.7	1.9	2.0	-1.1	0.2	2.2	1.3	2.0	1.6	-1.6	2.1	2.6	1.9	1.6
Gout (self-reported)	0.9	1.2	4.7	0.8	0.4	-0.6	1.1	-1.7	-1.3	0.6	0.5	0.2	-1.7	-1.3	-1.2	-1.5	0.7	-2.2	-1.2	-0.5	-0.5	-0.8	1.4	-0.8	-1.1	-1.0	-1.1
Whole body fat mass	0.9	3.8	18.9	-1.9	0.5	-1.1	-1.3	4.1	1.6	0.6	-4.3	1.9	1.7	1.8	1.9	1.8	-0.9	0.3	2.0	1.1	1.8	1.6	-1.1	2.1	2.5	1.6	1.7
Arm predicted mass (right)	0.9	4.4	18.7	-1.5	3.2	0.3	-1.1	1.4	2.0	3.4	2.1	4.3	2.7	2.7	1.9	2.4	1.3	2.2	1.8	2.0	1.3	1.1	0.3	1.6	1.1	2.0	1.8
Had major operations	0.9	1.1	4.1	1.4	-0.7	2.0	1.2	-1.0	-1.0	-0.8	0.7	-0.6	-0.5	-0.8	-1.1	-0.8	1.0	-0.1	-1.1	-1.7	-1.1	-1.3	-0.8	-1.1	-0.5	-1.0	-1.2
Illnesses of siblings: Diabetes	0.9	1.1	3.0	1.3	1.0	0.3	0.0	0.4	-1.3	0.8	0.3	0.8	-0.5	-1.1	-1.2	-1.0	0.0	-0.8	-0.8	-0.1	-1.3	-1.7	1.7	-1.3	-1.5	-1.3	-1.2
Arm fat mass (left)	0.9	3.6	14.6	-1.8	0.3	-1.1	-0.8	3.7	1.6	-0.0	-3.8	1.5	1.6	1.7	1.9	1.9	-1.3	0.1	2.2	1.2	2.0	1.8	-1.7	2.2	2.7	1.8	1.6
Irritability	0.9	1.5	4.1	-1.1	1.4	-1.4	-0.8	1.1	1.6	2.0	0.2	1.0	1.6	1.6	1.5	1.3	0.1	1.4	1.0	1.8	0.9	1.3	0.3	1.1	0.4	1.1	1.5
Depressed Affect (Nagel 2018)	0.8	1.6	6.4	-0.6	1.4	-0.4	-1.5	2.5	1.1	2.5	-0.7	1.9	1.9	1.2	1.1	1.1	1.0	1.4	1.0	1.3	0.0	0.3	1.1	0.6	-0.0	0.5	1.1
Bipolar Disorder (2011)	0.8	0.8	7.5	0.0	0.2	0.0	-0.9	1.4	0.2	1.7	-2.7	1.0	0.4	0.4	0.0	0.2	0.3	0.0	0.3	1.1	0.0	0.0	1.3	0.0	-0.7	0.0	0.3
Systolic blood pressure, automated reading	0.8	2.3	7.6	1.6	-0.5	-0.1	0.1	-0.1	-1.7	-0.3	-2.0	-0.3	-1.6	-2.0	-1.6	-2.1	-1.7	-1.1	-1.8	-1.0	-2.4	-1.2	1.6	-1.4	-1.0	-2.8	-1.2
Qualifications: CSEs or equivalent	0.8	1.0	2.5	-0.9	0.9	-0.0	-0.3	1.1	1.3	-0.0	-1.1	0.3	1.2	1.6	1.0	1.0	-0.2	1.3	1.2	1.1	0.9	1.0	-0.8	1.2	1.2	1.0	1.1
Fluid intelligence score	0.8	1.7	5.9	-0.6	-0.3	-1.2	-2.4	1.6	1.3	-0.7	1.6	1.7	2.2	1.6	1.2	1.2	-0.9	2.3	1.2	1.2	-0.1	0.6	0.0	0.8	0.8	0.2	1.3
Falls in the last year	0.8	1.1	4.9	0.4	1.2	0.3	-1.4	1.6	1.1	1.4	-0.5	0.4	2.2	1.5	1.0	1.4	0.6	1.7	1.1	1.0	0.0	-0.2	-0.2	0.2	-0.2	0.6	0.5
Headache pain in last month	0.8	1.4	3.2	-1.5	1.8	-0.7	-1.3	1.8	1.3	1.3	0.2	1.1	1.3	1.1	1.3	1.2	0.5	0.8	1.4	0.8	1.2	0.9	0.1	1.1	0.8	1.0	1.4
Arm fat-free mass (right)	0.8	3.8	19.5	-1.3	3.0	0.4	-1.2	1.2	1.8	3.4	2.1	4.4	2.5	2.5	1.6	2.1	1.2	2.0	1.4	1.8	1.0	0.8	0.6	1.3	0.8	1.7	1.6
Medication: Ibuprofen	0.8	1.0	4.7	0.1	2.2	0.2	-1.6	0.5	-0.2	1.6	-1.4	1.1	0.0	-0.1	-0.4	-0.6	1.1	0.5	-0.7	-0.5	-1.2	-0.6	2.0	-0.6	-1.1	-0.9	0.3
Pulse rate, automated reading	0.8	2.7	9.5	-0.0	2.8	0.6	-2.6	1.9	0.5	3.1	1.0	2.6	1.3	0.6	0.3	0.1	2.6	1.6	0.0	1.4	-1.4	-0.4	2.9	-0.2	-1.4	-1.1	0.9
Knee pain experienced in last month	0.8	1.3	5.8	-1.1	-0.6	-2.4	0.3	1.5	0.7	-0.8	-1.5	-0.5	-0.1	0.4	0.6	0.4	-1.2	-0.8	1.1	0.7	1.6	1.3	-1.9	1.2	1.5	0.9	0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	0.9	2.6	-1.3	-0.2	-1.6	-0.8	1.0	0.9	0.8	-0.1	0.4	0.5	0.6	1.0	0.7	-1.1	-0.1	1.2	1.1	1.2	1.3	-0.2	1.2	1.0	0.8	1.0
Average weekly red wine intake	0.8	1.1	5.7	-1.0	1.1	0.5	-2.1	1.1	0.7	0.5	-0.7	2.4	0.6	0.5	0.6	-0.0	-2.0	1.2	0.7	0.8	-0.3	0.7	1.2	0.8	0.8	-0.6	1.3
Medication for cholesterol	0.8	1.3	6.2	1.0	-2.0	0.4	1.2	-0.7	-0.4	-2.5	-0.4	-2.5	-0.8	0.0	-0.8	-0.5	0.7	0.3	-0.7	-1.6	-0.1	-0.4	-2.1	-0.7	0.2	0.2	-1.0
Back pain experienced in last month	0.8	1.1	5.2	-1.0	0.3	-1.7	-0.0	1.2	1.1	0.0	-2.3	0.1	0.6	1.3	1.0	0.8	0.1	0.6	0.9	0.9	0.9	1.5	-1.3	1.1	1.1	1.0	0.8
Illnesses of father: None of the above (group 1)	0.8	1.0	3.1	-1.3	-0.5	0.7	1.0	-1.0	1.3	0.2	0.9	-0.2	0.3	1.4	1.0	0.8	0.4	1.2	0.4	0.9	1.1	1.8	-1.3	1.2	1.1	1.5	1.1
Wears glasses or contact lenses	0.8	0.9	6.7	0.8	-0.5	1.3	-1.6	1.9	0.0	0.5	-2.6	1.1	1.0	0.1	-0.0	0.3	0.5	0.7	0.2	-0.5	-0.5	-1.2	0.3	-0.6	-0.7	-0.5	-0.4
Arm fat-free mass (left)	0.8	3.8	18.1	-1.2	3.0	0.8	-0.8	1.2	1.7	3.6	2.2	4.2	2.5	2.4	1.6	2.2	1.4	1.9	1.4	1.8	1.2	0.7	0.4	1.3	0.7	1.9	1.4
Bipolar Disorder or Schizophrenia	0.7	1.6	4.9	-1.8	-0.5	-2.2	-1.8	0.8	1.4	1.8	-0.4	1.8	0.6	1.5	1.3	0.9	-0.6	0.5	0.7	1.4	1.1	1.8	0.5	1.2	0.5	1.2	1.5
Ever used hormone-replacement therapy (HRT)	0.7	0.9	4.1	0.4	0.3	-0.8	-0.7	-0.5	-0.8	0.7	-0.1	1.0	-0.8	-1.3	-0.5	-1.0	-1.3	-1.8	-0.8	0.4	-1.0	-0.2	2.0	-0.4	-0.9	-1.3	-0.3
Eye problems/disorders: Diabetes related eye disease	0.7	0.7	2.7	0.5	1.4	1.1	-0.4	-0.5	-0.7	1.4	-0.0	0.1	-0.4	-0.7	-0.7	-0.8	-0.7	-0.3	-0.9	-0.7	-1.0	-0.8	1.6	-0.9	-1.2	-1.0	-0.4
Diabetes (father)	0.7	0.9	5.0	-0.5	-0.8	0.2	-1.3	1.3	0.8	-0.5	-1.3	-0.1	0.8	1.0	0.7	0.7	-2.2	0.9	0.8	0.5	0.4	0.5	-0.7	0.8	1.3	0.5	0.7
Current tobacco smoking	0.7	1.1	6.0	-0.2	2.5	1.2	0.5	-0.8	0.4	2.4	0.6	0.9	0.6	0.7	0.4	0.7	2.3	0.8	0.0	1.0	0.2	0.1	1.0	0.0	-1.0	1.0	0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	0.9	3.2	-0.0	1.2	0.5	-1.3	1.0	1.0	1.7	0.7	0.7	1.8	1.2	0.9	1.5	1.0	1.5	0.6	0.0	0.4	-0.2	-0.5	0.3	0.3	1.0	0.6
Had other major operations	0.7	0.8	5.8	0.6	-2.4	-0.7	1.4	-0.8	-0.5	-1.0	-1.5	-0.6	-0.7	-0.5	-0.5	-0.5	-1.5	-0.8	-0.6	0.5	-0.1	-0.1	-0.4	-0.5	-0.6	-0.2	-0.8
Noisy workplace	0.7	0.8	7.0	0.8	1.0	0.4	0.7	-0.3	-0.1	1.3	2.0	-0.3	0.7	0.2	-0.1	0.6	2.6	0.8	0.2	0.4	-0.0	-0.8	0.2	-0.7	-1.4	0.5	-0.5
Length of working week for main job	0.7	0.8	2.5	0.4	1.6	0.3	0.9	-1.6	-1.0	0.4	-0.1	1.1	-0.9	-0.9	-0.9	-0.9	0.7	-0.2	-1.0	-0.6	-1.0	-0.8	1.3	-0.8	-1.0	-0.8	-0.5
Peak expiratory flow (PEF)	0.7	1.6	7.9	0.7	0.0	0.8	0.6	-2.1	-0.8	1.8	2.8	1.4	-1.3	-0.1	-1.2	-1.4	-0.2	-0.2	-1.7	-0.6	-1.3	-0.5	1.6	-1.1	-1.5	-1.0	-1.0
Ever highly irritable/argumentative for 2 days	0.7	0.8	2.9	0.6	-0.6	-0.1	-0.4	-0.9	-0.9	-0.9	-0.1	-1.3	-1.1	-0.9	-0.9	-1.3	-0.9	-0.9	-1.4	-1.7	-0.9	-0.3	-0.1	-0.8	-0.5	-1.2	-0.6
Loud music exposure frequency	0.7	0.8	3.3	-0.8	1.3	-0.4	-1.0	0.3	0.8	1.8	-0.2	1.1	0.7	0.9	0.8	0.7	-1.2	0.5	1.0	1.1	1.1	1.1	0.1	0.7	0.1	0.8	0.8
Medication: Paracetamol	0.7	1.1	5.9	-0.9	0.3	0.3	-2.4	2.4	0.8	2.4	-0.2	0.1	1.0	0.8	0.8	0.7	-0.1	0.4	0.7	1.0	0.2	0.3	1.4	0.4	-0.5	0.3	0.9
Health satisfaction	0.7	0.9	2.4	1.3	-1.1	0.9	1.6	-0.6	-0.8	-0.0	-0.9	-1.4	-0.2	-0.7	-0.8	-0.1	1.2	-1.1	-0.5	-0.8	0.1	-1.2	-1.2	-1.0	-0.7	0.1	-1.4
Migraine (self-reported)	0.7	0.8	4.5	-0.8	-0.1	-0.0	-0.8	2.1	1.0	0.3	0.5	-1.2	0.9	1.3	0.8	0.9	0.2	1.6	0.9	0.6	0.5	0.5	-0.4	0.9	0.8	0.6	1.0
Overall health rating	0.7	1.5	7.3	1.3	0.7	1.4	0.2	0.3	-1.1	1.6	-0.4	0.1	-0.0	-0.8	-1.2	-0.6	2.7	-0.6	-1.2	-1.4	-1.5	-1.9	0.9	-1.6	-1.6	-0.9	-1.4
Supplements: Vitamin C	0.7	0.8	5.6	0.4	-1.0	0.5	0.7	-0.8	-0.5	-1.1	-2.4	-1.9	-0.9	-0.4	-0.8	-0.6	0.1	-0.2	-0.6	-1.2	-0.1	-0.3	-1.3	-0.5	-0.0	-0.3	-0.8
Smoking status: Current	0.7	1.2	6.7	-0.2	2.6	1.0	0.6	-0.8	0.3	2.6	0.6	1.1	0.4	0.6	0.3	0.5	2.3	0.6	-0.1	0.9	0.1	0.0	1.1	0.0	-1.0	0.8	0.4
Leg fat percentage (left)	0.7	2.4	30.1	0.2	-1.5	-0.5	0.6	2.7	-0.4	-1.5	-5.5	-0.7	-0.2	-0.7	-0.0	0.2	-0.9	-2.1	0.4	-0.8	0.9	-0.0	-2.2	0.3	1.4	0.3	-0.6
Number of operations (self-reported)	0.7	1.1	3.8	1.1	-1.9	0.7	1.6	-2.0	-0.8	-1.8	-0.0	-0.4	-0.8	-0.6	-0.9	-0.7	1.0	-0.2	-1.0	-0.9	-0.5	-0.7	-1.2	-0.9	-0.6	-0.5	-1.1
Deep venous thrombosis (DVT) (self-reported)	0.7	0.9	2.8	-0.9	0.8	0.5	-1.1	1.4	1.0	0.6	-0.2	1.7	1.0	1.2	1.0	0.9	-0.2	1.3	1.1	1.3	0.9	0.6	0.4	0.9	0.6	0.9	1.0
Arm predicted mass (left)	0.7	3.8	19.4	-1.1	3.2	0.9	-1.1	1.5	1.6	3.5	2.0	4.4	2.5	2.3	1.5	2.1	1.4	1.9	1.4	1.7	0.9	0.5	0.5	1.2	0.8	1.7	1.4
Verbal and Numeric Reasoning (VNR)	0.6	1.4	5.1	1.1	0.7	0.4	-1.1	1.0	0.1	1.1	1.9	1.0	1.8	0.3	0.0	0.5	2.2	1.9	0.1	0.9	-1.4	-1.2	1.8	-0.8	-1.5	-0.6	-0.1
Ovarian Cancer	0.6	0.8	7.0	0.1	-1.5	0.1	-0.3	-0.0	0.2	-2.6	-0.5	-0.2	0.0	0.2	0.1	-0.1	-2.2	0.3	0.2	-0.3	-0.2	0.1	-1.4	0.3	1.0	-0.3	0.1
Schizophrenia (2014)	0.6	1.3	3.7	-1.7	-0.4	-1.9	-1.8	0.3	1.3	1.0	1.6	1.7	0.6	1.5	1.0	0.8	0.5	1.0	0.5	0.8	0.8	1.4	0.0	1.1	0.9	1.0	1.2
Triglycerides	0.6	0.9	3.8	-0.7	1.0	-0.2	-0.9	1.3	0.9	2.0	-0.0	1.4	1.4	0.9	0.8	1.0	0.9	0.9	0.4	1.4	0.2	0.2	1.1	0.2	-0.7	0.7	0.8
Type 2 Diabetes (T2D) (2012)	0.6	0.7	4.0	-0.1	0.8	0.3	-1.2	0.9	0.3	1.7	0.0	0.8	0.4	0.2	0.1	-0.1	2.0	0.9	-0.5	-0.2	-0.7	-0.2	1.5	-0.4	-0.9	-0.6	0.3
Average weekly spirits intake	0.6	0.8	1.6	-0.9	0.8	-0.7	-0.2	1.2	0.9	0.9	-0.1	1.2	0.7	0.8	0.9	0.7	0.1	-0.1	1.3	1.2	0.9	1.1	-0.1	1.2	1.1	0.6	1.1
Age when periods started (menarche)	0.6	1.4	8.5	0.2	-0.4	-0.8	1.7	-1.9	-0.7	-1.6	2.1	-2.9	-1.8	-0.5	-1.0	-1.3	-0.1	-0.1	-1.0	-1.4	-0.3	0.0	-1.0	-0.1	0.9	-0.4	-0.6
High blood pressure (mother)	0.6	0.9	5.1	0.6	-1.6	-0.3	1.5	-0.7	-0.5	-1.6	0.4	-2.2	-0.5	-0.4	-0.5	0.0	1.1	-0.2	-0.1	-0.6	0.5	-0.6	-1.8	-0.3	0.2	0.5	-0.9
Impedance of arm (right)	0.6	2.8	6.3	-2.1	-0.0	-1.8	-2.5	1.8	2.0	-0.4	-1.8	0.2	1.3	1.9	1.9	1.1	-2.1	2.0	1.6	1.2	0.8	2.2	0.4	2.0	1.9	0.7	2.4
Qualifications: A levels/AS levels or equivalent	0.6	1.3	7.5	0.8	-2.7	0.5	1.0	-0.8	-1.0	-2.3	-0.4	-0.8	-1.2	-1.0	-0.9	-1.2	-0.3	-1.0	-1.0	-1.9	-0.9	-0.5	-0.7	-0.8	-0.1	-1.2	-1.0
Asthma	0.6	1.1	5.6	-0.2	-2.4	-1.3	1.0	-0.1	-0.2	-2.0	-0.9	-2.2	-1.0	-0.3	-0.2	-0.7	-1.8	-0.4	-0.6	-0.4	-0.3	0.7	-1.3	0.2	0.8	-0.4	-0.2
Pulse wave reflection index	0.6	0.8	6.5	-0.4	0.4	1.6	0.1	-0.8	0.4	-0.6	2.2	-0.8	-0.1	0.4	0.2	0.1	-2.5	0.7	0.0	0.0	0.3	0.6	-0.9	0.6	0.9	0.4	0.3
Blood clot in the leg (DVT)	0.6	0.8	4.1	-0.6	1.0	0.7	-1.6	1.4	0.8	0.9	-0.0	2.0	0.9	0.9	0.7	0.5	-0.2	1.3	0.9	0.9	0.2	0.3	0.9	0.6	0.3	0.3	0.9
Leg fat percentage (right)	0.6	2.2	28.9	0.1	-1.4	-0.3	0.3	2.6	-0.3	-1.4	-5.4	-0.3	0.0	-0.4	0.1	0.3	-1.2	-1.7	0.5	-0.7	0.9	0.2	-2.2	0.4	1.4	0.4	-0.4
Number of children fathered	0.6	0.6	2.8	-0.2	0.9	0.3	-1.5	0.5	0.5	0.8	-1.7	1.4	0.6	0.6	0.5	0.2	-0.8	1.4	0.1	0.8	-0.6	0.2	0.8	0.3	0.3	-0.2	0.8
Pulse wave peak to peak time	0.6	0.7	4.5	-0.9	0.2	-2.1	1.0	0.1	0.5	0.3	-1.3	-0.5	-0.2	0.5	0.5	0.3	0.3	-0.3	0.4	0.8	1.1	1.0	-0.1	1.0	1.0	0.9	0.6
Shortness of breath walking on level ground	0.6	0.7	3.7	0.3	-1.8	-0.7	0.5	0.9	0.4	-0.7	-1.6	-0.3	0.8	0.3	0.4	0.9	0.5	-0.0	0.9	0.1	1.0	-0.2	-1.9	0.1	0.2	1.0	-0.3
Neck or shoulder pain in last month	0.6	0.9	3.5	-0.5	-1.3	-0.2	-1.0	1.9	0.8	0.1	-0.4	-0.8	1.2	0.9	0.6	0.9	1.9	1.8	1.0	0.5	0.2	0.3	-1.1	0.2	0.1	0.5	0.5
Angina (self-reported)	0.6	0.7	4.3	0.6	0.8	0.7	-0.7	0.6	-0.4	0.5	-2.1	1.7	0.2	-0.3	-0.4	-0.3	-1.4	-0.4	-0.0	0.2	-0.6	-0.9	1.5	-0.6	-1.0	-0.7	-0.4
Leg fat mass (right)	0.6	2.2	13.9	-1.2	0.1	-0.7	-0.7	3.2	1.0	0.1	-3.7	1.4	1.2	1.1	1.2	1.4	-0.8	-0.2	1.4	0.3	1.5	1.0	-1.6	1.5	2.1	1.3	1.0
Leg pain on walking	0.6	0.7	6.2	1.0	0.0	-0.2	0.7	0.1	-0.8	-0.1	1.2	-0.2	-0.1	-0.9	-0.6	-0.2	2.5	-0.8	-0.2	-0.3	-0.5	-1.2	0.1	-1.0	-1.1	-0.4	-1.0
Commuting to job workplace: Car/motor vehicle	0.6	0.7	2.0	0.7	1.1	1.4	-0.3	0.3	-0.7	0.1	1.2	0.6	-0.2	-0.5	-0.9	-0.9	0.4	0.1	-0.9	-1.0	-1.3	-0.8	0.9	-0.9	-0.7	-1.3	-0.5
Illnesses of father: Heart disease	0.6	0.8	7.3	0.1	0.0	-1.4	-1.4	1.1	-0.2	-0.8	-2.7	-0.2	-0.4	-0.5	-0.1	-0.5	-1.8	-0.5	0.4	0.2	-0.2	-0.0	0.9	0.1	0.1	-0.7	0.0
Commuting to job workplace: Walk	0.6	0.6	1.6	-1.1	-0.7	-0.3	-0.5	0.6	0.8	-0.8	-1.0	-0.4	0.5	0.5	0.8	0.7	0.7	0.3	0.9	-0.6	0.9	0.9	-1.1	0.8	1.3	0.9	0.9
Osteoarthritis (self-reported)	0.6	0.8	2.0	1.0	-0.2	-0.6	1.2	-0.7	-1.1	-0.6	0.6	-1.3	-0.8	-1.4	-0.8	-0.9	0.1	-1.3	-0.6	-1.1	-0.8	-1.0	-0.2	-0.7	-0.3	-1.1	-0.9
Ever had prostate specific antigen (PSA) test	0.6	0.7	6.2	-0.4	0.8	0.6	-0.3	-0.4	0.2	0.1	-2.5	0.5	-0.1	0.0	0.3	-0.2	-2.5	-0.5	-0.2	0.6	-0.1	0.4	0.8	0.4	0.3	-0.3	0.4
Ever depressed for a whole week	0.6	0.7	1.6	0.7	-1.3	0.9	1.2	-1.2	-0.9	-0.5	0.5	-0.6	-1.2	-1.0	-0.8	-0.9	-0.2	-1.2	-0.5	-1.1	-0.1	-0.2	-0.6	-0.6	-0.3	-0.4	-1.0
Unable to work because of sickness or disability	0.6	0.8	4.5	-0.1	1.8	0.4	-1.1	1.1	0.6	2.1	0.4	1.3	1.4	0.7	0.5	1.0	1.1	0.7	0.5	0.4	-0.0	-0.5	0.2	0.1	-0.2	0.5	0.3
Intelligence (Savage-Jansen 2018)	0.5	1.4	3.5	-0.5	-1.2	-1.5	-1.3	1.9	1.2	-0.4	0.4	0.1	1.9	1.2	1.3	1.7	1.1	1.9	1.8	1.6	0.8	0.7	-0.6	0.6	0.1	1.2	0.8
Age at First Birth	0.5	0.7	3.7	-0.6	-1.6	-0.9	0.7	-0.7	0.2	-1.8	0.2	-1.9	-0.3	0.2	0.3	0.2	-0.7	-0.4	0.6	0.1	0.9	0.7	-1.1	0.5	0.6	0.7	0.2
Crohns Disease (2012)	0.5	0.8	2.2	-1.3	-0.4	-0.6	0.3	0.4	0.9	0.5	-1.2	0.5	0.3	0.9	1.0	1.0	-0.7	-0.1	0.8	1.3	1.5	1.4	-0.9	1.1	0.8	1.5	0.8
Ulcerative Colitis	0.5	0.8	3.8	-0.6	-0.0	0.6	-1.4	0.9	0.9	1.0	-1.5	1.5	0.7	0.9	0.8	0.7	-1.9	0.3	0.4	1.0	0.6	0.6	0.2	0.5	-0.0	0.7	0.6
Systolic Blood Pressure	0.5	2.4	9.6	1.1	1.2	-0.1	-0.2	-0.8	-1.6	1.0	-0.8	0.6	-1.6	-1.9	-1.5	-2.2	-1.8	-1.0	-1.7	-0.5	-2.3	-0.9	3.1	-1.4	-1.7	-2.8	-0.8
Chronotype (morning person)	0.5	1.3	7.0	0.4	-1.6	-0.7	2.0	-1.8	-0.5	-2.0	-0.6	-2.7	-0.9	-0.6	-0.2	0.1	-0.7	-1.0	-0.2	-0.3	1.1	0.3	-1.6	0.0	0.4	0.8	-0.8
Sensitivity / hurt feelings	0.5	0.9	2.9	-0.9	-0.9	-0.5	0.1	0.7	0.6	-1.3	-1.4	-1.0	-0.1	0.2	0.7	0.5	-1.3	-0.4	1.2	0.7	1.3	1.2	-1.1	1.3	1.7	0.7	0.7
Relative age of first facial hair	0.5	1.0	2.7	0.7	0.6	1.1	1.4	-1.4	-1.1	-0.8	0.4	-0.3	-1.0	-1.2	-1.1	-1.0	1.4	-1.2	-0.9	-1.6	-0.7	-0.9	0.4	-1.1	-0.8	-0.9	-1.0
Other serious medical condition/disability diagnosed by doctor	0.5	0.6	2.5	-0.5	1.0	0.4	-1.5	1.1	0.7	0.5	0.8	1.2	1.0	1.2	0.5	0.4	0.4	1.6	0.3	0.2	-0.3	0.1	0.2	0.3	0.5	-0.0	0.7
Angina	0.5	0.7	3.9	0.2	1.0	0.6	-0.9	0.8	-0.1	0.6	-1.9	2.0	0.4	0.0	-0.1	-0.1	-1.4	-0.2	0.2	0.4	-0.4	-0.6	1.5	-0.3	-0.7	-0.5	-0.0
Hayfever, allergic rhinitis or eczema	0.5	1.0	5.5	-0.2	0.7	0.9	-2.0	2.3	0.7	1.7	0.8	0.8	1.6	1.1	0.5	0.8	0.6	1.7	0.3	0.1	-0.5	-0.4	0.8	-0.2	-0.6	-0.1	0.7
Hearing difficulty/problems with background noise	0.5	0.7	3.0	0.5	-1.6	0.2	0.2	1.0	0.5	-1.7	-1.2	-0.8	1.3	0.2	0.6	0.8	-1.0	0.3	0.9	-0.3	0.2	-0.2	-1.7	0.1	0.7	0.1	0.0
Worrier / anxious feelings	0.5	1.0	3.2	0.4	-0.9	-0.1	1.8	-1.3	-0.8	-1.2	-1.8	-1.6	-1.1	-1.3	-0.5	-0.5	0.7	-1.7	-0.1	-1.1	0.7	0.1	-0.8	-0.3	0.1	0.0	-0.8
Depression (self-reported)	0.5	0.6	1.4	1.2	0.2	0.6	0.8	-0.9	-0.9	0.6	0.3	-0.1	-0.8	-1.0	-0.9	-0.7	0.3	-0.7	-0.9	-0.3	-0.7	-1.0	1.1	-0.9	-1.2	-0.5	-1.1
Medication: Lansoprazole	0.5	0.6	3.6	-0.7	0.9	-1.3	-0.3	0.5	0.4	-0.5	-1.9	0.0	-0.1	0.1	0.6	0.1	-1.0	-0.5	0.6	1.0	0.5	1.0	0.1	1.0	1.0	0.1	0.7
Pulse wave Arterial Stiffness index	0.5	0.6	4.7	0.5	0.3	2.2	-1.3	0.2	-0.1	0.2	1.5	1.1	0.7	0.0	-0.1	0.1	-0.2	0.8	-0.1	-0.6	-0.9	-0.8	0.1	-0.7	-0.8	-0.5	-0.2
Exposure to tobacco smoke at home	0.5	0.5	2.0	-0.2	1.3	-0.8	1.2	0.1	0.1	1.2	1.1	1.3	0.2	-0.1	0.2	0.5	1.4	-0.8	0.5	0.2	0.8	-0.1	-0.2	0.4	0.2	0.6	0.1
Medication: Ventolin 100micrograms inhaler	0.5	0.6	1.8	-0.9	0.4	-0.7	-0.9	0.8	1.0	0.3	-0.3	-0.6	0.8	0.7	1.1	0.7	-0.5	1.4	0.7	0.6	0.3	0.7	0.1	1.1	1.1	0.2	1.3
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	1.6	-1.3	0.6	-0.7	0.3	0.4	0.8	0.4	-1.2	0.5	0.4	0.7	0.8	0.7	-0.7	-0.0	0.7	0.7	1.1	1.2	-0.6	0.9	0.7	0.9	0.9
Smoking status: Previous	0.5	0.7	4.4	-0.1	-0.3	-1.8	-0.6	0.9	0.2	-1.5	-0.4	-0.1	0.5	-0.6	0.5	-0.0	-2.1	-0.5	0.8	0.6	-0.3	0.4	0.1	0.8	1.1	-1.1	0.7
Asthma (self-reported)	0.5	1.0	5.3	-0.2	-2.3	-1.2	0.9	0.0	-0.2	-1.8	-1.1	-2.1	-0.9	-0.3	-0.2	-0.6	-1.8	-0.3	-0.5	-0.3	-0.3	0.7	-1.1	0.2	0.7	-0.4	-0.1
Miserableness	0.5	0.9	2.6	-0.9	0.6	-1.6	-1.6	1.0	1.1	1.0	-0.3	0.8	1.1	1.2	1.0	0.7	-0.2	1.5	0.5	0.6	0.1	1.0	0.1	0.9	0.8	0.3	1.2
Mother’s age at death	0.5	0.6	2.9	0.8	-0.9	0.1	-1.0	1.3	-0.5	-0.1	-1.7	-0.7	0.1	-0.3	-0.5	-0.4	0.4	0.3	-0.7	-0.7	-1.1	-0.9	0.9	-0.8	-0.8	-1.0	-0.5
Medication: Blood pressure	0.5	1.0	5.5	-0.9	1.6	-1.2	-0.3	0.3	0.4	1.9	-1.0	2.4	0.2	0.1	0.6	0.2	-0.3	-0.4	0.4	1.8	0.4	0.8	1.8	0.6	-0.4	0.2	0.7
Leg fat mass (left)	0.5	2.1	13.9	-1.1	0.0	-0.7	-0.5	3.3	0.9	-0.1	-3.7	1.1	1.1	0.9	1.1	1.2	-0.7	-0.4	1.3	0.2	1.5	0.9	-1.6	1.4	2.1	1.2	0.8
Depression (Nagel 2018)	0.4	0.6	2.9	1.2	0.4	1.2	-0.1	0.3	-0.4	1.7	0.0	0.9	0.5	-0.3	-0.4	-0.2	0.9	-0.2	-0.7	-0.6	-0.6	-1.2	0.3	-0.9	-0.9	-0.6	-0.7
Schizophrenia (2018)	0.4	0.9	5.5	-1.4	-1.2	-2.4	-1.0	-0.1	0.9	0.3	0.8	1.6	-0.0	0.9	0.7	0.2	0.1	0.0	0.2	0.5	0.7	1.4	-0.3	1.0	0.9	0.6	0.8
Schizophrenia vs Biploar Disorder	0.4	0.5	3.1	-0.3	-1.2	-0.0	0.1	-0.6	0.2	-1.1	1.8	-0.2	-0.1	0.4	-0.1	0.1	0.8	0.8	-0.3	-0.6	0.6	0.4	-1.4	0.3	1.0	0.4	-0.1
Alzheimer’s Disease (including proxy)	0.4	0.6	3.2	0.7	-0.6	0.1	1.0	-1.3	-0.6	-1.0	1.4	0.1	-0.7	-0.9	-0.4	-0.3	-1.8	-1.2	-0.5	-0.3	0.2	-0.3	-0.7	-0.4	-0.1	0.1	-0.9
Breast Cancer	0.4	0.9	4.6	1.0	-2.1	0.1	1.0	-1.2	-0.3	-0.9	-2.1	-1.4	-0.5	-0.1	-0.4	0.0	-1.0	-0.5	-0.2	0.3	0.3	-0.2	-1.4	-0.5	-0.6	0.6	-1.1
Body Mass Index (BMI) (2010)	0.4	0.6	3.0	0.6	-1.7	0.6	0.5	0.3	0.1	-1.4	-1.7	-0.5	0.4	0.4	0.1	0.5	-0.8	0.2	0.1	0.2	0.2	-0.0	-1.7	-0.2	0.2	0.5	-0.4
HDL Cholesterol	0.4	0.6	2.0	0.9	-0.8	0.7	0.1	-0.8	-0.8	-1.4	0.5	-1.4	-0.6	-1.1	-0.6	-0.8	0.4	-0.4	-0.4	-1.1	-0.9	-0.6	-0.5	-0.5	0.0	-1.0	-0.7
Lupus	0.4	0.6	2.4	-0.9	-0.8	-1.6	0.3	-0.0	0.2	-1.0	1.2	-0.5	-0.4	-0.0	0.4	0.2	-0.7	-0.6	0.3	0.8	0.8	1.0	-0.6	1.0	1.2	0.6	0.5
Smoking Status	0.4	1.0	9.3	-0.6	3.0	-0.5	-0.1	0.2	0.6	1.9	0.8	1.2	1.0	0.3	0.8	0.8	0.4	0.1	0.6	1.3	0.2	0.4	1.1	0.8	0.1	0.4	1.0
Cardiovascular Disease	0.4	1.2	4.3	-1.6	1.2	-2.1	0.6	1.3	0.7	1.4	-0.9	0.1	-0.2	0.3	1.0	0.6	-0.0	-1.4	1.2	1.3	1.7	1.3	0.4	1.5	0.9	1.0	1.0
Neuroticism	0.4	1.1	2.9	-1.4	0.2	-1.7	-0.8	0.9	1.3	0.5	0.2	0.5	1.1	0.9	1.3	1.0	0.3	0.7	1.3	1.1	0.9	1.3	-0.1	1.4	1.3	0.8	1.4
Hearing difficulty/problems: Yes	0.4	0.5	2.5	-0.4	1.5	0.5	0.1	1.4	0.4	0.7	-0.4	0.7	0.9	0.2	0.5	0.7	1.6	0.1	1.1	-0.6	0.6	-0.1	-0.5	0.4	0.6	0.4	0.5
Multivitamins +/- minerals	0.4	0.5	2.8	0.4	0.2	0.4	-0.7	0.1	0.5	1.1	1.7	0.5	0.9	0.8	0.2	0.3	1.0	1.7	-0.0	0.5	-0.2	-0.4	0.2	-0.2	-0.5	-0.0	0.1
Stomach or abdominal pain in last month	0.4	0.5	2.2	-0.8	-0.9	-0.5	0.4	0.3	0.2	-1.0	-1.5	-0.8	-0.7	0.2	0.2	-0.2	-1.1	-0.5	0.3	0.9	0.6	0.9	-0.4	0.8	0.8	0.4	0.3
Supplements: Glucosamine	0.4	0.5	6.6	0.3	-0.2	-0.2	0.1	-0.4	-0.4	0.1	2.6	0.7	-0.5	-0.5	-0.5	-0.9	0.2	0.2	-0.8	0.1	-1.0	-0.2	0.8	-0.0	0.3	-1.1	-0.2
Qualifications: None of the above	0.4	0.8	2.9	0.5	1.4	1.1	-1.7	0.4	0.2	1.7	-1.1	1.5	1.0	0.4	0.3	0.5	0.3	0.6	0.2	0.6	-0.5	-0.7	1.5	-0.3	-0.9	0.1	0.1
Number of live births	0.4	0.6	2.9	0.4	0.3	1.7	-1.4	0.8	-0.3	1.0	0.4	-0.2	0.1	-0.1	-0.4	-0.4	1.4	0.6	-0.3	0.1	-0.7	-0.7	1.1	-0.5	-0.8	-0.7	-0.2
Illnesses of mother	0.4	0.5	2.9	-0.1	1.7	0.4	-1.1	-0.3	0.0	1.2	1.0	1.0	0.1	0.2	-0.2	-0.4	0.3	1.0	-0.3	-0.3	-0.8	0.0	1.1	-0.1	-0.1	-0.5	0.3
Breastfed as a baby	0.4	0.5	4.1	0.0	0.1	-1.0	0.7	-0.4	-0.6	-0.4	0.7	-0.6	-0.7	-1.2	-0.2	-0.4	-2.0	-1.6	0.2	-0.1	0.3	0.1	-0.1	0.0	0.3	-0.3	-0.3
Hair/balding pattern: Pattern 4	0.4	1.0	3.5	-0.5	1.2	1.7	-0.9	-0.3	1.0	1.8	1.1	1.4	1.2	1.6	0.6	0.7	0.1	1.9	0.1	0.9	0.2	-0.0	0.9	0.1	-0.7	0.5	0.8
Comparative body size at age 10	0.4	1.2	3.0	1.3	-1.7	1.1	1.5	-0.0	-1.1	-1.6	-0.7	-1.0	-0.4	-1.3	-1.0	-0.6	1.1	-1.5	-0.7	-0.3	-0.7	-1.2	-0.9	-1.2	-1.2	-0.8	-1.4
Medication: Seretide 50 evohaler	0.4	0.5	4.4	-0.4	-1.2	-0.4	0.2	0.1	0.5	-1.1	-2.1	-0.6	-0.0	0.7	0.3	0.1	-0.3	0.4	0.1	-0.2	0.1	0.7	-1.3	0.4	0.7	0.4	0.2
Family relationship satisfaction	0.4	0.5	3.2	0.6	0.3	1.5	-0.9	0.7	0.4	0.3	-0.1	0.3	1.5	0.7	0.1	0.7	0.4	1.8	0.6	-0.1	-0.5	-0.9	-0.4	-0.4	-0.4	0.0	-0.0
Hypertension (Self-reported)	0.4	1.2	6.5	-1.6	1.2	-2.5	0.1	1.1	0.6	0.8	-1.4	0.6	-0.3	-0.1	0.9	0.3	0.4	-1.3	0.9	0.6	1.4	1.3	0.3	1.4	1.2	0.4	1.1
Osteoporosis (self-reported)	0.4	0.5	1.7	-1.1	-1.0	-1.3	-0.0	-0.4	0.2	-0.2	0.3	0.2	-0.8	-0.1	0.4	-0.1	-0.1	-1.0	0.4	0.9	0.9	1.1	0.3	0.9	0.6	0.4	0.5
Ever taken oral contraceptive pill	0.4	0.4	1.4	-0.9	0.5	-0.8	1.0	-1.1	-0.0	0.4	-0.4	-0.1	-1.1	0.2	-0.2	-0.4	-1.2	-0.9	-0.4	0.2	0.5	0.9	0.4	0.5	0.3	0.5	0.1
Hearing aid user	0.4	0.4	1.3	-1.0	0.5	-0.8	-0.7	1.0	0.7	0.1	0.3	0.6	0.3	0.8	0.6	0.2	-0.8	0.1	0.5	0.2	0.2	1.0	-0.1	0.9	1.1	0.0	1.0
Medication: Paracetamol	0.4	0.7	4.4	-0.6	0.2	0.1	-1.9	1.3	0.7	2.1	-0.0	0.3	0.8	0.7	0.6	0.5	-0.3	0.3	0.3	0.8	0.0	0.3	1.2	0.2	-0.6	0.1	0.7
Alcohol drinker status: Previous	0.4	0.4	4.8	-0.2	-1.4	-0.4	0.2	0.2	0.1	-0.4	0.5	-0.5	-0.5	-0.0	0.1	-0.1	-2.2	-0.1	0.2	-0.0	0.3	0.5	-0.9	0.4	0.8	0.1	0.0
Alzheimer’s Disease (in mother)	0.3	0.3	1.7	0.7	-0.2	0.0	-0.1	-0.7	-0.3	0.0	1.1	0.6	0.3	-0.7	0.0	0.3	-1.3	-1.0	-0.1	-0.2	0.2	-0.4	-0.6	-0.5	-0.4	-0.1	-0.5
BMI	0.3	1.6	12.2	0.2	-1.3	-0.3	1.6	1.4	-1.0	-1.7	-3.5	-1.1	-0.9	-0.9	-0.8	-0.4	0.6	-2.2	-0.3	-1.3	0.6	-0.4	-1.9	-0.2	0.7	0.1	-1.0
Hypothyroidism (self reported)	0.3	0.6	8.5	0.3	-0.6	0.0	0.5	1.2	-0.3	-0.1	-2.9	1.3	-0.2	0.1	-0.3	-0.2	1.0	-0.3	-0.2	-0.4	-0.1	-0.1	-0.1	-0.3	-0.2	0.2	-0.5
Hand grip strength (left)	0.3	0.8	7.2	0.0	1.1	-0.1	0.4	-0.9	0.0	1.7	2.7	1.6	-0.1	0.3	-0.2	-0.0	1.0	0.4	-0.6	0.7	-0.3	-0.0	1.6	-0.2	-0.8	0.1	0.0
Hand grip strength (right)	0.3	0.9	4.4	0.8	0.2	0.4	1.0	-1.3	-0.5	1.8	2.1	0.9	-0.5	-0.1	-0.7	-0.4	1.2	0.1	-1.2	0.4	-0.8	-0.4	1.5	-0.8	-1.4	-0.2	-0.7
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	1.5	0.6	-0.1	1.1	0.2	0.4	-0.1	-0.6	-0.8	0.0	0.4	0.3	-0.3	0.1	1.2	0.3	-0.5	-0.5	-0.1	-0.7	-0.3	-0.5	-0.3	0.1	-0.4
Serious illness, injury or assault to yourself	0.3	0.4	1.5	-0.4	0.3	-0.5	-0.1	0.2	0.6	1.2	1.2	1.0	0.5	1.0	0.3	0.3	0.6	0.9	0.3	0.6	0.2	0.7	0.3	0.2	-0.3	0.4	0.3
Body mass index (BMI)	0.3	1.3	12.4	-0.3	-0.8	-0.3	0.6	2.6	0.0	-0.6	-3.5	-0.1	0.3	0.0	0.3	0.7	-0.2	-1.3	0.8	0.0	1.1	0.2	-1.8	0.6	1.1	0.9	-0.1
Past tobacco smoking	0.3	0.5	1.5	0.1	-0.9	1.2	0.6	-1.0	-0.3	0.7	-0.1	-0.7	-0.6	0.4	-0.5	-0.0	1.2	0.3	-0.6	-0.4	0.5	-0.2	-0.3	-0.7	-1.0	1.0	-0.9
Nervous feelings	0.3	0.5	3.1	-0.4	-0.0	1.0	0.1	-1.4	-0.2	-0.9	1.7	-1.5	-0.5	-0.5	-0.1	-0.2	0.8	-0.2	0.2	-0.8	0.4	0.2	-0.7	0.2	0.4	0.3	-0.0
Allergy	0.3	0.6	3.0	-0.3	-0.3	-1.1	1.6	-1.7	-0.2	-0.7	-0.5	-0.5	-0.7	-0.5	0.1	0.2	-0.0	-1.4	0.4	0.4	1.2	0.6	-0.7	0.4	0.5	0.9	-0.3
Pain all over the body in last month	0.3	0.3	2.4	0.1	0.7	1.4	-0.2	-0.3	0.3	1.6	0.6	0.2	0.7	0.7	0.1	0.5	0.3	0.6	-0.3	0.0	-0.2	-0.3	0.0	-0.2	-0.4	0.4	-0.1
Hip circumference	0.3	1.2	8.0	-0.8	-0.1	-0.5	0.1	2.6	0.7	0.1	-2.8	0.8	1.0	1.0	0.8	1.0	-0.3	-0.2	0.8	0.3	1.0	0.6	-1.1	1.1	1.6	1.0	0.6
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	1.9	0.5	0.7	0.9	-1.2	1.3	0.3	0.9	0.0	1.0	1.1	0.5	0.1	0.2	0.3	1.4	0.3	-0.8	-0.7	-0.5	-0.5	-0.1	0.5	-0.4	0.2
Hair/balding pattern: Pattern 3	0.3	0.4	5.6	0.3	-0.5	0.2	-0.6	0.3	-0.0	-0.3	-0.5	-0.3	-0.2	0.2	-0.2	-0.5	-2.4	0.6	-0.4	0.6	-0.8	0.0	0.3	-0.2	-0.2	-0.7	-0.1
Happiness	0.3	0.4	2.0	0.9	-0.4	0.9	-0.1	-0.5	-0.3	-0.7	0.1	0.0	0.6	-0.0	-0.3	0.3	-0.4	0.0	-0.1	-1.1	-0.2	-0.9	-1.4	-0.8	-0.3	-0.0	-0.8
Prospective memory result	0.3	0.4	2.5	-0.2	-1.6	0.0	0.1	0.5	-0.2	-1.2	-1.3	-1.2	-0.7	-0.3	-0.2	-0.4	-0.4	-0.7	-0.1	-0.7	0.1	0.1	-0.5	0.1	0.5	-0.3	-0.2
Lung cancer (father)	0.3	0.4	2.5	0.5	-1.6	0.6	1.2	-0.1	0.1	0.1	-0.9	-1.0	0.0	0.3	-0.2	0.2	0.7	0.4	-0.1	-0.1	0.3	-0.2	-0.6	-0.4	-0.6	0.5	-0.6
Hypothyroidism/myxoedema (self-reported)	0.3	0.6	8.2	0.4	-0.8	-0.2	0.5	0.7	-0.6	-0.1	-2.9	0.7	-0.8	-0.1	-0.7	-0.7	-0.1	-0.6	-0.6	-0.3	-0.4	-0.1	-0.1	-0.4	-0.3	-0.2	-0.8
High blood pressure (siblings)	0.3	0.5	3.1	-0.0	-0.1	-1.5	0.0	1.3	0.2	0.3	-1.8	-0.3	0.5	0.0	0.4	0.6	1.3	-0.7	0.9	0.1	0.8	-0.2	-0.3	0.2	-0.1	0.4	0.0
Age at first live birth	0.3	0.5	4.0	-0.2	-0.4	-0.3	0.7	-0.5	0.2	-0.9	1.2	-2.0	-0.2	0.2	0.1	-0.1	-1.2	0.6	0.1	-0.0	0.3	0.6	-0.9	0.3	0.8	0.0	0.1
Medication: Allopurinol	0.3	0.4	2.0	0.1	-0.4	-0.5	0.8	-1.3	-0.6	-0.2	0.3	-0.0	-0.9	-0.4	-0.5	-0.6	1.0	-1.4	-0.7	-0.6	0.1	-0.3	-0.0	-0.2	-0.2	-0.0	-0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.4	1.4	-0.6	0.1	-0.3	-0.4	0.8	0.4	-0.2	-0.0	0.9	0.2	0.3	0.5	0.4	0.4	-0.3	0.8	0.0	0.9	0.4	-1.1	0.9	1.2	0.4	0.5
Alcohol intake frequency.	0.3	0.7	4.3	0.1	0.1	0.2	-0.3	1.7	0.2	-0.0	-2.1	-0.8	0.3	0.9	-0.0	0.2	-0.8	1.1	-0.2	-0.9	0.2	-0.1	-2.0	0.1	1.0	0.5	-0.2
Illness, injury, bereavement, stress in last 2 years	0.3	0.3	1.0	-0.8	-0.8	-1.0	-0.7	0.5	0.6	-0.3	0.1	-0.7	0.4	0.5	0.6	0.4	0.1	1.0	0.3	0.1	0.2	0.7	-0.5	0.5	0.8	0.1	0.7
Mood swings	0.3	0.5	1.5	-0.5	0.7	-0.8	-0.8	0.8	0.7	1.2	-0.5	1.0	0.9	0.6	0.6	0.5	1.1	0.7	0.4	0.8	0.2	0.5	0.7	0.4	-0.2	0.4	0.7
Eye problems/disorders: Cataract	0.3	0.4	2.0	-0.3	-1.1	-1.4	-0.4	0.5	0.6	-0.4	-0.2	0.6	0.4	0.5	0.6	0.3	-1.2	-0.0	0.4	0.7	0.4	0.7	-0.5	0.5	0.5	0.1	0.4
Mouth/teeth dental problems: Mouth ulcers	0.3	0.4	4.1	-0.5	-2.0	-0.6	-0.0	-0.3	0.2	-1.1	0.2	-1.1	-0.5	-0.0	0.3	-0.0	-0.5	-0.5	0.2	0.4	0.6	0.6	-0.3	0.5	0.3	0.4	0.2
Mineral and other dietary supplements	0.3	0.4	1.3	-0.4	-0.7	-1.2	0.6	0.5	0.5	0.1	-0.4	-0.8	0.4	0.5	0.5	0.8	-0.4	-0.2	0.4	0.3	1.0	0.6	-0.9	0.3	0.2	1.1	0.2
Guilty feelings	0.3	0.5	1.0	-0.7	-0.6	-0.5	-0.0	0.1	0.9	0.4	0.4	0.1	0.9	0.5	1.0	0.8	0.5	0.8	0.8	1.0	0.6	0.8	0.2	0.8	0.5	0.7	1.0
Commuting to job workplace: Public transport	0.3	0.4	1.5	-0.7	-0.3	-0.9	-0.2	-0.8	0.5	0.2	1.0	0.4	0.3	0.4	0.7	0.7	-0.6	0.1	0.4	1.2	0.8	0.6	0.0	0.6	0.2	0.8	0.5
Pain type(s) experienced in last month: Hip pain	0.3	0.4	1.4	-0.4	0.4	-1.2	-0.7	0.6	0.8	-0.0	-0.2	-0.2	0.6	0.9	0.7	0.5	-1.1	0.7	0.5	1.2	0.3	0.8	-0.4	0.6	0.3	0.2	0.6
Fractured/broken bones in last 5 years	0.3	0.4	2.8	0.6	-0.9	1.5	-0.3	1.0	0.0	0.0	-1.7	-0.6	0.1	0.0	-0.0	-0.1	-1.0	0.2	-0.2	0.2	-0.4	-0.3	0.1	-0.3	-0.5	-0.2	-0.2
Vascular/heart problems diagnosed by doctor	0.3	0.8	3.3	1.0	-1.6	1.7	0.3	-1.6	-0.4	-1.2	1.8	-1.2	-0.1	-0.1	-0.6	-0.1	-0.2	0.4	-0.8	-0.4	-0.6	-0.6	-0.8	-0.8	-0.5	0.1	-0.8
Worry (Nagel 2018)	0.2	0.5	2.8	0.6	-1.1	0.3	1.0	-1.7	-0.5	-0.6	0.0	-1.1	-0.8	-0.9	-0.4	-0.6	-0.0	-1.1	-0.2	-0.3	0.3	-0.1	-0.3	-0.4	-0.4	-0.1	-0.7
Major Depression (MDD)	0.2	0.3	1.7	-0.0	-0.0	-0.6	0.2	1.3	0.1	1.1	0.0	-0.2	0.5	0.2	0.1	0.6	1.3	0.4	0.3	-0.2	0.2	-0.2	-0.4	0.1	0.1	0.6	-0.2
LDL Cholesterol	0.2	0.2	1.9	0.7	0.3	1.4	-0.5	0.2	-0.3	-0.1	0.1	-0.6	-0.1	-0.3	-0.4	-0.4	-0.5	0.3	-0.4	0.1	-0.7	-0.7	0.1	-0.5	-0.4	-0.4	-0.5
Neuroticism (2016)	0.2	0.3	1.2	-0.6	-1.0	-0.9	0.1	-0.5	0.1	-0.5	-0.4	-1.1	-0.3	-0.1	-0.0	-0.1	-0.1	0.2	0.0	-0.5	0.4	0.4	-0.8	0.4	0.9	0.2	0.3
Blood White Count	0.2	1.5	8.5	2.1	-0.3	1.4	0.6	0.0	-0.7	2.0	-1.5	1.0	0.1	-0.1	-0.8	-0.1	1.5	0.2	-1.0	-0.2	-0.7	-1.4	0.7	-1.9	-2.9	0.0	-1.6
Lung FEV1/FVC ratio	0.2	0.8	4.2	-0.3	1.3	0.4	-0.7	-0.7	1.0	0.1	0.4	2.1	1.3	1.3	0.7	1.1	-0.8	1.2	0.7	0.8	0.8	0.5	-0.4	0.3	-0.0	0.7	0.6
Tanning	0.2	2.6	27.8	0.4	3.3	-0.7	-0.8	-1.0	0.2	2.1	5.3	1.4	0.8	0.4	-0.0	-0.1	2.0	0.9	-0.9	0.5	-1.1	-0.6	2.1	-0.5	-1.1	-0.8	0.4
Frequency of depressed mood in last 2 weeks	0.2	0.3	2.2	0.9	1.0	0.5	0.1	0.0	-0.2	1.5	0.6	0.8	0.7	-0.3	-0.1	0.2	0.4	-0.3	-0.2	-0.4	-0.4	-0.9	0.3	-0.6	-0.7	-0.5	-0.3
Medication for hormone replacement therapy	0.2	0.2	1.8	-0.4	-0.2	-0.3	-0.1	-0.9	-0.0	-0.5	0.5	0.5	-0.3	-0.0	0.1	0.0	-1.3	0.2	-0.2	0.4	-0.2	0.5	0.1	0.3	0.4	0.0	0.3
Medication: Co-codamol	0.2	0.2	2.4	-0.0	0.1	-0.3	0.5	-0.4	0.3	0.0	-0.6	-1.6	0.1	0.3	0.2	0.3	0.3	0.5	-0.1	-0.2	0.1	0.1	-1.1	0.1	0.4	0.3	0.0
Impedance of leg (right)	0.2	1.0	2.7	0.8	-1.0	0.0	-1.4	-1.1	-0.6	-0.8	-1.0	0.0	-0.8	-0.6	-0.8	-1.4	-1.6	-0.2	-1.5	-1.3	-1.5	-0.2	0.7	-1.1	-0.8	-1.7	-0.6
High blood pressure	0.2	0.6	3.5	-0.9	1.1	-1.9	0.4	1.0	0.1	0.7	-1.4	0.5	-0.5	-0.4	0.3	-0.1	0.5	-1.2	0.5	0.2	0.9	0.7	0.4	0.8	0.6	0.0	0.5
Impedance of leg (left)	0.2	1.2	3.6	0.8	-0.8	-0.2	-1.3	-0.7	-0.8	-0.7	-1.2	-0.2	-1.1	-1.0	-0.9	-1.6	-1.4	-0.8	-1.5	-1.4	-1.5	-0.4	1.1	-1.1	-0.8	-1.9	-0.6
Hair/balding pattern: Pattern 2	0.2	0.3	1.4	-0.4	-0.3	-0.7	0.2	1.1	-0.2	-0.3	-0.9	0.5	-0.3	-0.6	0.2	-0.0	-0.5	-1.2	0.6	0.2	0.5	0.6	-0.3	0.5	0.8	0.0	0.2
Mouth/teeth dental problems	0.2	0.4	1.9	-0.7	0.5	-0.5	0.8	-0.0	0.4	-0.2	1.0	-0.2	-0.1	0.3	0.3	0.2	-0.8	0.1	0.1	0.2	0.6	0.8	-0.8	0.8	1.4	0.6	0.4
Hayfever/allergic rhinitis (self-reported)	0.2	0.3	1.5	-0.1	0.3	-0.6	-1.0	0.4	-0.2	0.6	0.5	0.6	-0.2	-0.4	-0.2	-0.5	1.0	0.0	-0.1	-0.4	-0.6	-0.0	1.2	-0.3	-0.7	-1.0	0.3
Illnesses of siblings	0.2	0.3	1.8	-0.1	-0.1	1.3	-0.2	-1.4	0.0	0.1	1.2	0.1	-0.4	0.2	-0.2	-0.3	-0.2	0.4	-0.9	-0.2	-0.4	0.3	-0.0	-0.0	0.1	-0.1	0.0
Father’s age at death	0.2	0.2	1.4	0.1	1.1	0.3	0.1	0.5	0.4	0.5	-0.2	1.2	0.8	0.6	0.3	0.5	-0.0	0.5	0.4	-0.1	0.1	-0.0	-0.6	0.2	0.4	0.2	0.2
Tense / ‘highly strung’	0.2	0.3	1.4	0.5	0.3	0.6	-0.4	-0.9	-0.3	1.0	-0.2	0.7	-0.1	-0.2	-0.4	-0.5	-0.2	-0.1	-0.6	-0.6	-0.7	-0.6	0.6	-0.9	-1.2	-0.7	-0.4
Qualifications: O levels/GCSEs or equivalent	0.2	0.4	1.5	0.5	0.1	0.8	-0.1	0.2	-0.4	0.1	0.8	-0.3	-0.3	-0.4	-0.6	-0.7	0.2	-0.3	-0.6	-0.7	-0.9	-0.6	1.0	-0.8	-0.9	-1.2	-0.4
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	1.6	-0.2	0.6	-0.1	-1.2	0.6	0.1	0.8	0.2	0.4	0.3	0.2	0.2	0.2	0.3	0.8	0.5	0.2	-0.3	-0.2	1.3	-0.0	-0.7	-0.1	0.4
Chronic bronchitis/emphysema (mother)	0.2	0.2	1.2	-0.6	0.3	-0.3	0.3	-0.4	0.1	-1.1	-0.2	-0.2	-0.2	-0.1	0.3	0.2	-0.3	-0.1	0.5	0.2	0.6	0.5	-0.3	0.6	0.8	0.3	0.4
Worry too long after embarrassment	0.2	0.4	3.0	-0.1	0.0	-1.4	-0.1	-0.8	0.1	-1.7	0.3	0.2	-0.4	-0.4	0.1	-0.4	-0.9	-0.9	0.3	0.2	0.2	0.6	-0.5	0.5	0.7	-0.5	0.2
Qualifications: College or University degree	0.2	0.5	1.8	0.9	-0.9	0.4	0.0	-0.7	-0.5	-0.4	0.7	-1.0	-0.2	-0.6	-0.4	-0.4	-1.1	-0.1	-0.2	0.0	-0.8	-0.8	0.9	-0.9	-1.4	-0.7	-0.5
Age at last live birth	0.2	0.3	1.5	0.1	0.4	0.2	-0.8	0.6	0.2	0.8	0.7	-0.8	0.2	0.5	-0.1	-0.4	0.4	1.2	-0.2	-0.2	-0.5	-0.0	0.5	-0.2	-0.3	-0.7	0.2
Friendships satisfaction	0.2	0.3	1.3	0.8	0.2	0.5	-0.4	-0.3	0.2	-0.3	0.6	-0.1	1.1	0.2	0.2	0.6	-0.5	0.6	0.3	-0.3	-0.1	-0.6	-1.1	-0.4	0.0	0.1	-0.3
Supplements: Fish oil (including cod liver oil)	0.2	0.2	1.4	0.1	0.8	0.9	-1.2	0.3	0.1	-0.1	-0.5	0.8	0.3	0.0	0.1	-0.1	-0.5	0.6	0.4	-0.0	-0.2	-0.3	0.1	0.0	0.2	-0.3	0.2
Ever smoked	0.2	0.4	2.0	0.0	1.0	-0.2	-0.4	0.9	0.7	-0.6	0.4	0.7	1.4	0.2	0.8	0.7	-0.2	0.5	0.8	0.7	-0.3	0.0	0.1	0.6	0.7	-0.4	1.0
Average weekly beer plus cider intake	0.2	0.3	2.2	-0.0	1.2	-0.1	0.4	0.4	0.1	0.8	1.5	1.2	0.7	0.1	-0.1	0.3	0.3	-0.0	0.3	0.5	0.2	-0.5	0.8	-0.1	-0.5	0.2	0.1
Supplements: Calcium	0.2	0.2	1.3	-0.0	0.4	1.1	-1.1	-0.3	0.1	0.1	0.5	0.2	0.4	-0.0	0.1	0.1	1.0	0.7	0.3	-0.1	-0.1	-0.5	0.1	0.2	0.3	-0.1	0.2
Impedance of whole body	0.2	1.2	6.6	-1.0	-0.9	-1.6	-2.0	0.7	0.8	-1.1	-2.6	-0.2	0.0	0.6	0.7	-0.3	-2.4	0.4	0.3	0.0	-0.1	1.4	0.5	0.7	0.9	-0.5	1.1
Alzheimer’s Disease (in father)	0.1	0.1	1.4	-0.0	-0.0	0.6	-0.3	-0.0	0.1	-1.2	0.2	0.0	0.1	0.1	0.1	0.1	-0.8	-0.0	0.1	0.0	0.5	-0.2	-0.4	-0.1	0.1	0.2	-0.0
Blood Platelet Count	0.1	1.1	8.1	-0.8	-0.9	-0.8	0.4	1.0	1.1	0.9	-0.5	0.0	0.2	1.9	0.7	0.6	2.9	1.3	-0.1	0.9	1.0	1.2	0.4	0.3	-0.7	1.4	0.5
Respiratory disease	0.1	0.2	0.8	0.0	-0.7	-0.4	-0.6	0.6	-0.1	0.2	-0.9	-0.0	-0.2	0.1	-0.2	-0.4	0.1	0.5	-0.6	-0.4	-0.8	0.1	0.5	-0.3	-0.4	-0.5	-0.1
Hair Pigment	0.1	3.4	7.0	-2.0	2.5	-1.7	-1.7	0.6	1.9	2.0	-1.2	2.1	1.7	1.5	2.1	1.9	-2.6	-0.4	2.1	1.6	2.1	2.2	-0.1	2.0	1.7	1.5	2.0
Average weekly fortified wine intake	0.1	0.1	0.4	-0.2	-0.4	0.3	0.3	0.2	0.2	-0.2	-0.6	0.7	0.5	0.0	0.3	0.2	0.2	-0.3	0.0	0.4	-0.1	-0.1	0.3	-0.0	-0.3	0.0	0.2
Taking other prescription medications	0.1	0.2	0.9	-0.2	-0.7	-1.0	0.4	0.9	0.0	-0.6	-0.7	-0.5	-0.3	0.1	-0.1	-0.3	0.4	0.3	0.1	-0.4	-0.1	0.2	-0.6	0.2	0.6	-0.2	-0.1
Alcohol usually taken with meals	0.1	0.2	1.8	0.2	0.1	0.3	-1.4	0.1	-0.1	0.3	-0.0	0.3	0.3	-0.0	-0.1	-0.2	0.2	0.9	-0.2	-0.8	-0.4	-0.4	0.4	-0.5	-0.5	-0.5	-0.0
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.1	1.6	0.1	0.3	0.5	-0.3	-0.1	0.2	0.2	-0.2	-1.3	0.2	0.2	0.1	0.1	-0.2	1.0	0.2	0.2	-0.3	-0.1	0.1	0.0	-0.1	0.0	0.2
Wheeze or whistling in the chest in last year	0.1	0.2	1.1	-0.0	-0.6	-0.6	0.7	-0.4	0.0	-0.4	-0.7	-0.9	-0.3	0.1	-0.1	-0.1	0.5	0.3	-0.2	-0.6	-0.1	0.4	-1.0	0.1	0.3	0.4	-0.1
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.5	-0.1	-0.5	-0.0	-0.5	0.5	0.0	-0.5	0.2	0.6	0.0	0.1	-0.1	-0.3	-0.1	0.5	0.2	-0.2	-0.7	0.1	0.2	0.0	0.1	-0.6	0.3
Emphysema/chronic bronchitis	0.1	0.1	0.8	0.3	0.2	0.1	0.6	-0.0	-0.4	-0.1	-0.9	-0.1	-0.5	-0.5	-0.3	-0.3	0.2	-0.6	-0.1	-0.5	-0.1	-0.1	-0.3	-0.1	0.2	0.0	-0.4
Suffer from ‘nerves’	0.1	0.2	0.6	-0.2	0.5	-0.6	0.5	-0.4	0.1	0.7	0.8	-0.5	-0.3	-0.3	0.1	-0.0	-0.0	-0.2	0.5	0.6	0.7	0.3	0.2	0.4	0.2	0.2	0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.1	0.1	1.3	-0.0	-0.6	0.2	0.1	0.1	0.1	-0.1	0.7	-0.3	0.3	0.3	0.1	0.3	1.1	0.1	-0.0	0.4	-0.1	0.0	0.2	-0.2	-0.7	0.1	0.1
Qualifications: nursing, teaching	0.1	0.2	1.3	0.5	-1.1	0.1	0.7	0.4	-0.3	-0.7	0.6	-0.1	-0.0	-0.4	-0.2	-0.2	0.0	-0.4	0.0	-0.6	-0.2	-0.3	-0.3	-0.2	0.2	-0.6	-0.3
High cholesterol (Self-reported)	0.1	0.2	1.3	-0.2	-0.1	-0.9	0.3	0.3	-0.4	1.0	-0.1	0.2	-0.7	-0.6	-0.1	-0.3	0.1	-1.1	0.1	0.4	0.3	0.1	0.7	0.1	-0.3	-0.2	-0.1
Commuting to job workplace: Cycle	0.1	0.2	1.0	0.3	-1.0	1.0	0.2	0.2	-0.0	-0.4	0.3	-0.4	-0.3	0.2	-0.1	-0.1	-0.2	0.5	0.1	0.1	0.3	-0.2	-0.8	-0.0	-0.0	0.3	-0.4
Neuroticism (Nagel 2018)	0.0	0.1	0.8	0.1	-0.3	-0.2	-0.1	0.4	0.3	0.4	-0.9	0.5	0.3	0.1	0.3	0.1	0.1	-0.1	0.5	0.6	0.3	0.2	0.1	0.3	0.0	0.1	0.1
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0

Hub : Genes

MAPK13

Models

Trait associations