[Hub]/) : Traits : Whole body water mass : ← →

chr5:129,797,129-132,839,137

Best TWAS P=1.32e-26 · Best GWAS P=6.12e-21 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	LOC553103	0.05	0.02	bslmm	433	0.03	3.2e-04	-6.58	5.3	1.3e-07	0.42	0.81	0.01	FALSE
2	CommonMind	Brain Pre-frontal Cortex	PDLIM4	0.11	0.18	lasso	5	0.18	8.0e-21	-6.06	-6.4	1.7e-10	-0.69	1.00	0.00	TRUE
3	GTEx	Adipose Subcutaneous	HINT1	0.10	0.07	enet	16	0.06	8.8e-06	-8.78	-10.7	1.3e-26	-0.39	0.06	0.92	TRUE
4	GTEx	Adipose Subcutaneous	SLC22A5	0.05	0.04	lasso	4	0.04	4.2e-04	9.07	-7.4	1.1e-13	-0.84	0.04	0.94	FALSE
5	GTEx	Adipose Subcutaneous	AC034220.3	0.11	0.11	lasso	10	0.09	4.8e-08	-7.60	7.6	3.0e-14	0.71	0.99	0.01	FALSE
6	GTEx	Adipose Visceral Omentum	AC034220.3	0.10	0.09	lasso	7	0.08	7.3e-05	-7.54	7.5	4.7e-14	0.72	0.40	0.35	FALSE
7	GTEx	Adrenal Gland	AC034220.3	0.12	0.11	lasso	16	0.08	7.7e-04	-7.61	7.6	3.1e-14	0.71	0.65	0.15	FALSE
8	GTEx	Artery Aorta	P4HA2	0.12	0.14	lasso	2	0.11	1.2e-06	9.38	9.4	6.0e-21	0.97	0.01	0.99	FALSE
9	GTEx	Artery Aorta	HINT1	0.07	0.07	enet	8	0.06	4.7e-04	-8.45	-9.7	4.0e-22	-0.34	0.10	0.48	FALSE
10	GTEx	Artery Aorta	AC034220.3	0.08	0.06	lasso	3	0.05	1.1e-03	-7.65	8.7	2.5e-18	0.75	0.41	0.38	FALSE
11	GTEx	Artery Aorta	P4HA2-AS1	0.08	0.03	lasso	3	0.01	6.6e-02	9.19	9.3	1.0e-20	0.99	0.02	0.96	FALSE
12	GTEx	Artery Tibial	P4HA2	0.12	0.15	lasso	6	0.14	3.2e-11	9.37	9.8	8.9e-23	0.98	0.01	0.99	FALSE
13	GTEx	Artery Tibial	HINT1	0.11	0.04	enet	18	0.06	1.0e-05	-8.32	-10.6	2.3e-26	-0.56	0.06	0.90	FALSE
14	GTEx	Artery Tibial	LYRM7	0.10	0.03	lasso	3	0.04	3.1e-04	-6.31	5.7	1.5e-08	0.21	0.52	0.08	FALSE
15	GTEx	Artery Tibial	SLC22A5	0.18	0.12	enet	8	0.12	2.5e-09	9.07	-8.0	1.0e-15	-0.83	0.03	0.97	FALSE
16	GTEx	Artery Tibial	P4HA2-AS1	0.10	0.09	lasso	4	0.11	1.0e-08	9.36	9.2	4.2e-20	0.96	0.01	0.99	FALSE
17	GTEx	Brain Caudate basal ganglia	AC034220.3	0.41	0.45	enet	19	0.46	8.8e-15	-7.54	8.0	1.9e-15	0.73	0.98	0.02	FALSE
18	GTEx	Brain Cortex	AC034220.3	0.43	0.39	lasso	15	0.17	2.4e-05	-7.54	7.3	2.4e-13	0.70	0.92	0.08	FALSE
19	GTEx	Brain Frontal Cortex BA9	AC034220.3	0.31	0.20	lasso	14	0.21	3.3e-06	-7.85	6.2	7.7e-10	0.65	0.63	0.23	FALSE
20	GTEx	Brain Hippocampus	AC034220.3	0.21	0.15	lasso	14	0.18	5.8e-05	-7.85	8.7	3.3e-18	0.85	0.07	0.87	FALSE
21	GTEx	Brain Nucleus accumbens basal ganglia	SLC22A5	0.15	0.00	enet	24	0.05	1.4e-02	-7.70	5.4	5.2e-08	0.45	0.10	0.15	FALSE
22	GTEx	Brain Nucleus accumbens basal ganglia	AC034220.3	0.24	0.24	enet	34	0.24	3.7e-07	-7.68	7.8	9.5e-15	0.71	0.83	0.11	FALSE
23	GTEx	Breast Mammary Tissue	SLC22A5	0.10	0.02	enet	16	0.06	4.5e-04	9.30	-6.9	6.3e-12	-0.71	0.10	0.86	TRUE
24	GTEx	Breast Mammary Tissue (Female)	SLC22A5	0.04	-0.01	lasso	3	0.01	1.3e-01	-4.30	-6.8	1.5e-11	-0.57	0.05	0.15	FALSE
25	GTEx	Cells EBV-transformed lymphocytes	SLC22A5	0.37	0.05	lasso	13	0.10	2.8e-04	9.30	-8.2	2.0e-16	-0.77	0.04	0.92	FALSE
26	GTEx	Cells Transformed fibroblasts	PDLIM4	0.08	0.09	lasso	1	0.07	6.4e-06	-6.23	-6.2	4.7e-10	-0.68	0.80	0.07	FALSE
27	GTEx	Cells Transformed fibroblasts	HINT1	0.10	0.06	lasso	2	0.05	2.1e-04	-8.32	-9.1	8.9e-20	-0.35	0.08	0.90	FALSE
28	GTEx	Cells Transformed fibroblasts	SLC22A5	0.32	0.28	lasso	7	0.35	1.6e-27	-7.49	-8.5	1.6e-17	-0.84	0.22	0.78	FALSE
29	GTEx	Colon Sigmoid	AC034220.3	0.18	0.11	lasso	12	0.06	3.7e-03	-7.84	7.4	1.8e-13	0.70	0.25	0.15	FALSE
30	GTEx	Colon Transverse	SLC22A5	0.12	0.07	enet	8	0.07	2.5e-04	9.30	-7.8	6.9e-15	-0.81	0.06	0.89	FALSE
31	GTEx	Colon Transverse	AC034220.3	0.30	0.15	lasso	3	0.11	8.4e-06	-7.65	8.1	4.1e-16	0.73	0.92	0.04	FALSE
32	GTEx	Esophagus Gastroesophageal Junction	SEPT8	0.22	0.08	lasso	12	0.10	2.2e-04	-6.96	7.6	4.1e-14	0.61	0.36	0.47	TRUE
33	GTEx	Esophagus Mucosa	P4HA2	0.23	0.10	lasso	6	0.14	6.1e-10	9.38	9.3	1.3e-20	0.93	0.01	0.99	FALSE
34	GTEx	Esophagus Mucosa	SLC22A5	0.16	0.16	enet	8	0.16	6.3e-11	9.30	-9.4	8.2e-21	-0.95	0.01	0.99	FALSE
35	GTEx	Esophagus Mucosa	AC034220.3	0.08	0.03	lasso	3	0.05	4.7e-04	-7.85	7.7	1.2e-14	0.71	0.94	0.04	FALSE
36	GTEx	Esophagus Mucosa	P4HA2-AS1	0.09	0.06	lasso	6	0.08	5.4e-06	9.38	8.9	3.9e-19	0.96	0.02	0.98	FALSE
37	GTEx	Esophagus Muscularis	AC034220.3	0.12	0.08	enet	20	0.07	3.8e-05	-7.65	7.1	1.7e-12	0.64	0.82	0.08	FALSE
38	GTEx	Heart Atrial Appendage	AC034220.3	0.16	0.09	enet	17	0.18	1.7e-08	-7.61	8.1	4.5e-16	0.78	0.52	0.48	FALSE
39	GTEx	Heart Left Ventricle	AC034220.3	0.25	0.22	lasso	6	0.25	8.6e-14	-7.65	8.3	8.2e-17	0.71	0.97	0.03	FALSE
40	GTEx	Liver	AC034220.3	0.30	0.16	lasso	6	0.16	3.9e-05	-7.61	6.1	1.1e-09	0.57	0.59	0.05	FALSE
41	GTEx	Lung	SLC22A5	0.10	0.15	enet	11	0.13	3.4e-10	9.30	-9.0	3.3e-19	-0.93	0.02	0.98	FALSE
42	GTEx	Muscle Skeletal	AC034220.3	0.27	0.23	lasso	9	0.24	9.1e-24	-7.54	7.8	5.2e-15	0.77	1.00	0.00	FALSE
43	GTEx	Muscle Skeletal	MIR3936	0.04	0.01	lasso	4	0.00	9.9e-02	-6.23	8.0	1.7e-15	0.83	0.09	0.65	FALSE
44	GTEx	Nerve Tibial	P4HA2	0.19	0.12	enet	26	0.14	6.2e-10	-7.61	8.4	3.6e-17	0.86	0.01	0.99	FALSE
45	GTEx	Nerve Tibial	LYRM7	0.05	0.02	enet	11	0.04	7.0e-04	-5.90	5.6	1.9e-08	0.23	0.34	0.37	FALSE
46	GTEx	Nerve Tibial	AC034220.3	0.15	0.11	lasso	5	0.10	1.9e-07	-7.61	7.8	6.7e-15	0.71	0.99	0.01	FALSE
47	GTEx	Nerve Tibial	P4HA2-AS1	0.14	0.05	lasso	8	0.08	3.8e-06	8.29	9.2	3.9e-20	0.89	0.03	0.97	FALSE
48	GTEx	Ovary	PDLIM4	0.25	0.22	enet	10	0.05	2.1e-02	-4.29	5.4	7.3e-08	0.60	0.29	0.35	FALSE
49	GTEx	Ovary	AC004041.2	0.21	-0.01	lasso	2	-0.01	7.7e-01	-5.64	7.5	9.6e-14	0.65	0.06	0.27	FALSE
50	GTEx	Pancreas	P4HA2	0.22	0.21	lasso	13	0.20	5.3e-09	-5.14	6.8	7.8e-12	0.59	0.76	0.22	FALSE
51	GTEx	Pancreas	P4HA2-AS1	0.16	0.16	lasso	5	0.16	3.2e-07	-5.14	6.0	1.6e-09	0.51	0.60	0.31	TRUE
52	GTEx	Pituitary	AC034220.3	0.25	0.22	lasso	12	0.18	3.1e-05	-6.65	7.4	1.7e-13	0.67	0.66	0.10	FALSE
53	GTEx	Prostate	AC034220.3	0.38	0.37	lasso	5	0.37	3.0e-10	-7.65	7.0	1.8e-12	0.69	0.88	0.11	FALSE
54	GTEx	Skin Not Sun Exposed Suprapubic	PDLIM4	0.13	0.08	lasso	2	0.06	2.6e-04	9.30	-8.5	2.7e-17	-0.84	0.04	0.93	FALSE
55	GTEx	Skin Not Sun Exposed Suprapubic	SLC22A4	0.13	0.00	lasso	4	0.01	7.1e-02	-2.60	-5.9	4.6e-09	-0.64	0.15	0.09	FALSE
56	GTEx	Skin Not Sun Exposed Suprapubic	SLC22A5	0.13	0.05	lasso	8	0.05	8.3e-04	-7.68	-8.5	1.5e-17	-0.82	0.14	0.86	FALSE
57	GTEx	Skin Sun Exposed Lower leg	PDLIM4	0.09	0.08	lasso	8	0.09	1.0e-07	9.38	-9.4	4.2e-21	-0.91	0.02	0.98	TRUE
58	GTEx	Skin Sun Exposed Lower leg	SLC22A5	0.25	0.21	lasso	3	0.20	1.4e-16	9.07	-9.2	4.4e-20	-0.90	0.03	0.97	FALSE
59	GTEx	Spleen	SLC22A5	0.26	0.28	lasso	4	0.28	6.6e-08	9.30	9.5	2.3e-21	0.88	0.02	0.94	FALSE
60	GTEx	Stomach	SLC22A5	0.09	0.04	lasso	4	0.01	9.0e-02	-7.01	-7.8	5.1e-15	-0.71	0.07	0.60	FALSE
61	GTEx	Stomach	AC034220.3	0.17	0.15	enet	21	0.16	4.2e-08	-6.72	7.9	3.0e-15	0.68	0.99	0.01	FALSE
62	GTEx	Testis	P4HA2	0.14	0.13	lasso	5	0.11	1.4e-05	9.38	9.6	8.3e-22	0.96	0.01	0.99	FALSE
63	GTEx	Testis	PDLIM4	0.15	0.07	enet	8	0.05	2.5e-03	-7.85	8.2	2.0e-16	0.71	0.24	0.15	FALSE
64	GTEx	Testis	RAPGEF6	0.50	0.35	lasso	4	0.32	6.5e-15	-8.16	-8.6	9.1e-18	-0.32	0.78	0.22	FALSE
65	GTEx	Testis	AC034220.3	0.15	0.12	lasso	9	0.12	4.4e-06	-7.54	7.5	5.3e-14	0.72	0.86	0.05	FALSE
66	GTEx	Thyroid	P4HA2	0.08	0.07	enet	9	0.06	3.5e-05	9.37	8.4	3.2e-17	0.98	0.01	0.99	FALSE
67	GTEx	Thyroid	PDLIM4	0.05	0.02	enet	5	0.01	3.1e-02	8.29	-8.3	1.3e-16	-0.90	0.05	0.89	FALSE
68	GTEx	Thyroid	SLC22A5	0.17	0.07	lasso	5	0.13	4.8e-10	-0.22	-5.3	1.1e-07	-0.67	0.06	0.94	FALSE
69	GTEx	Thyroid	AC034220.3	0.29	0.29	lasso	5	0.31	4.8e-24	-6.68	6.0	1.8e-09	0.47	1.00	0.00	FALSE
70	GTEx	Thyroid	P4HA2-AS1	0.08	0.06	enet	14	0.05	1.6e-04	9.37	8.5	2.8e-17	0.91	0.01	0.99	FALSE
71	GTEx	Uterus	P4HA2	0.58	-0.01	lasso	5	0.02	1.6e-01	-3.72	5.5	3.8e-08	0.41	0.05	0.38	FALSE
72	GTEx	Whole Blood	SLC22A4	0.07	0.05	enet	16	0.05	4.6e-05	-7.49	-8.4	4.0e-17	-0.71	0.11	0.81	FALSE
73	GTEx	Whole Blood	SLC22A5	0.09	0.12	lasso	2	0.10	1.7e-09	9.30	-9.3	1.4e-20	-0.89	0.01	0.99	FALSE
74	GTEx	Whole Blood	AC034220.3	0.08	0.05	enet	31	0.06	4.0e-06	9.07	-8.9	7.7e-19	-0.79	0.06	0.93	FALSE
75	GTEx	Whole Blood	AC116366.6	0.05	0.04	lasso	17	0.03	5.7e-04	-4.60	6.3	2.8e-10	0.50	0.35	0.39	FALSE
76	METSIM	Adipose	P4HA2	0.09	0.08	lasso	12	0.09	2.4e-13	9.36	9.0	1.5e-19	0.87	0.01	0.99	FALSE
77	METSIM	Adipose	PDLIM4	0.05	0.04	lasso	4	0.02	2.8e-04	8.31	-8.2	1.7e-16	-0.87	0.78	0.16	FALSE
78	METSIM	Adipose	SLC22A4	0.05	0.02	lasso	3	0.03	8.4e-06	4.57	-5.7	1.6e-08	-0.50	0.93	0.02	FALSE
79	METSIM	Adipose	SLC22A5	0.05	0.08	lasso	1	0.08	1.0e-11	9.30	-9.3	1.4e-20	-0.89	0.02	0.98	FALSE
80	NTR	Blood	SLC22A4	0.02	0.00	blup	423	0.01	5.2e-04	4.57	-7.5	9.6e-14	-0.67	0.15	0.82	FALSE
81	ROSMAP	Brain Pre-frontal Cortex	PDLIM4	0.25	0.27	lasso	4	0.26	2.7e-33	-6.20	-6.9	5.0e-12	-0.75	1.00	0.00	FALSE
82	ROSMAP	Brain Pre-frontal Cortex	SLC22A4	0.03	0.05	lasso	2	0.04	1.2e-05	-8.85	-9.2	2.5e-20	-0.73	0.34	0.60	FALSE
83	ROSMAP	Brain Pre-frontal Cortex	AC034220.3	0.04	0.02	blup	415	0.04	1.3e-05	-3.39	5.5	4.8e-08	0.62	0.94	0.04	FALSE
84	YFS	Blood	CDC42SE2	0.14	0.05	lasso	9	0.07	3.1e-22	-8.26	6.3	3.2e-10	0.20	0.15	0.85	FALSE
85	YFS	Blood	LYRM7	0.03	0.01	bslmm	243	0.01	7.0e-05	-6.44	-5.8	8.0e-09	-0.11	0.50	0.05	FALSE
86	YFS	Blood	SLC22A4	0.10	0.12	enet	47	0.14	5.1e-42	-7.58	-6.1	8.5e-10	-0.71	1.00	0.00	FALSE
87	YFS	Blood	SLC22A5	0.38	0.36	bslmm	430	0.37	3.0e-128	9.30	-10.1	5.0e-24	-0.88	0.01	0.99	FALSE
88	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	PDLIM4	0.05	0.01	enet	4	0.02	1.2e-02	-5.64	-5.5	3.2e-08	-0.56	0.08	0.07	FALSE
89	The Cancer Genome Atlas	Breast Invasive Carcinoma	P4HA2	0.03	0.02	blup	47	0.03	3.1e-06	9.36	8.5	2.7e-17	0.86	0.00	0.99	FALSE
90	The Cancer Genome Atlas	Breast Invasive Carcinoma	PDLIM4	0.05	0.05	lasso	4	0.05	9.0e-11	-6.20	-6.2	5.0e-10	-0.71	0.99	0.01	FALSE
91	The Cancer Genome Atlas	Breast Invasive Carcinoma	SLC22A4	0.05	0.01	enet	7	0.02	1.6e-05	9.30	-7.1	1.7e-12	-0.82	0.01	0.98	FALSE
92	The Cancer Genome Atlas	Breast Invasive Carcinoma	SLC22A5	0.05	0.07	enet	11	0.09	5.3e-17	-6.72	-8.0	1.4e-15	-0.68	1.00	0.00	FALSE
93	The Cancer Genome Atlas	Colon Adenocarcinoma	SLC22A5	0.08	0.04	blup	92	0.07	1.2e-04	-7.49	-7.9	2.1e-15	-0.75	0.03	0.91	FALSE
94	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	SLC22A4	0.02	0.02	lasso	1	0.02	3.0e-03	-6.96	-7.0	3.5e-12	-0.58	0.12	0.52	FALSE
95	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	SLC22A5	0.06	0.05	blup	93	0.08	1.2e-09	-7.62	-8.0	1.4e-15	-0.76	0.06	0.94	TRUE
96	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PDLIM4	0.09	0.02	lasso	6	0.05	4.5e-06	-5.64	-7.2	6.5e-13	-0.69	0.15	0.73	FALSE
97	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SLC22A4	0.03	0.03	lasso	1	0.02	3.5e-03	-7.68	-7.7	1.6e-14	-0.71	0.35	0.27	FALSE
98	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	CDC42SE2	0.10	0.07	lasso	1	0.06	2.6e-04	-5.45	5.5	5.1e-08	0.15	0.06	0.56	FALSE
99	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	SLC22A4	0.04	0.03	blup	108	0.01	7.1e-02	-6.71	-6.8	1.4e-11	-0.63	0.12	0.15	FALSE
100	The Cancer Genome Atlas	Brain Lower Grade Glioma	HINT1	0.06	0.03	enet	5	0.03	5.2e-04	-6.13	-7.4	1.5e-13	-0.25	0.08	0.41	FALSE
101	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	PDLIM4	0.08	0.03	blup	67	0.05	2.4e-03	-6.65	-5.3	1.0e-07	-0.62	0.04	0.36	FALSE
102	The Cancer Genome Atlas	Lung Adenocarcinoma	LYRM7	0.03	0.01	enet	10	0.02	7.5e-04	-6.24	9.0	2.2e-19	0.37	0.01	0.91	FALSE
103	The Cancer Genome Atlas	Lung Adenocarcinoma	SLC22A5	0.06	0.03	lasso	4	0.02	9.3e-04	-7.49	-8.0	9.0e-16	-0.68	0.07	0.70	FALSE
104	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	C5orf56	0.07	0.01	blup	98	0.03	3.2e-04	-4.77	5.3	1.0e-07	0.36	0.25	0.08	FALSE
105	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	SLC22A4	0.04	0.01	blup	111	0.03	3.0e-04	-1.54	-5.7	1.0e-08	-0.64	0.05	0.76	FALSE
106	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	SLC22A5	0.05	0.03	blup	93	0.05	1.9e-06	-6.71	-8.0	1.5e-15	-0.74	0.04	0.96	FALSE
107	The Cancer Genome Atlas	Prostate Adenocarcinoma	P4HA2	0.04	0.01	blup	47	0.03	4.4e-04	-4.32	5.3	1.0e-07	0.50	0.05	0.18	FALSE
108	The Cancer Genome Atlas	Prostate Adenocarcinoma	PDLIM4	0.32	0.36	enet	13	0.37	3.8e-40	-5.64	-7.1	1.4e-12	-0.77	1.00	0.00	FALSE
109	The Cancer Genome Atlas	Prostate Adenocarcinoma	SLC22A4	0.09	0.07	blup	108	0.09	3.0e-09	-7.61	-8.4	3.2e-17	-0.78	0.11	0.89	FALSE
110	The Cancer Genome Atlas	Prostate Adenocarcinoma	SLC22A5	0.12	0.05	lasso	4	0.08	1.8e-08	-4.92	-6.5	1.0e-10	-0.44	0.96	0.00	FALSE
111	The Cancer Genome Atlas	Stomach Adenocarcinoma	SLC22A5	0.05	0.01	blup	92	0.02	1.1e-02	-6.31	-6.2	6.3e-10	-0.50	0.09	0.13	FALSE
112	The Cancer Genome Atlas	Thyroid Carcinoma	C5orf56	0.06	0.04	blup	98	0.03	1.3e-03	-4.78	8.4	2.8e-17	0.55	0.80	0.11	FALSE
113	The Cancer Genome Atlas	Thyroid Carcinoma	HINT1	0.07	0.04	lasso	2	0.01	1.8e-02	-7.88	-7.9	3.1e-15	-0.32	0.00	0.98	FALSE
114	The Cancer Genome Atlas	Thyroid Carcinoma	IRF1	0.05	0.02	blup	83	0.03	1.5e-03	6.36	7.8	7.7e-15	0.79	0.05	0.09	FALSE
115	The Cancer Genome Atlas	Thyroid Carcinoma	P4HA2	0.21	0.35	enet	10	0.35	4.7e-35	9.36	9.1	9.9e-20	0.98	0.00	1.00	FALSE
116	The Cancer Genome Atlas	Thyroid Carcinoma	SLC22A5	0.03	0.02	lasso	1	0.01	2.6e-02	-7.49	-7.5	7.1e-14	-0.72	0.02	0.72	FALSE