[Hub]/) : Traits : Whole body water mass :

chr12:55,601,472-58,222,672

Best TWAS P=3.26e-16 · Best GWAS P=1.97e-16 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex HSD17B6 0.38 0.22 bslmm 343 0.24 2.4e-28 -5.72 -5.2 2.2e-07 -0.03 1.00 0.00 FALSE
2 CommonMind Brain Pre-frontal Cortex PRIM1 0.31 0.24 enet 7 0.24 1.1e-28 -7.92 8.1 5.6e-16 -0.01 0.00 1.00 TRUE
3 CommonMind Brain Pre-frontal Cortex RPS26 0.48 0.62 lasso 5 0.63 5.9e-99 -6.17 -6.1 1.0e-09 0.64 1.00 0.00 FALSE
4 GTEx Artery Tibial STAT6 0.08 0.03 enet 4 0.02 1.3e-02 -5.17 -5.3 9.5e-08 0.00 0.29 0.05 TRUE
5 GTEx Artery Tibial RPS26 0.07 0.02 enet 5 0.01 3.5e-02 -6.17 -6.0 1.6e-09 0.65 0.24 0.16 FALSE
6 GTEx Brain Caudate basal ganglia RP11-977G19.11 0.31 0.25 lasso 5 0.28 1.2e-08 4.87 -5.2 1.5e-07 0.29 0.86 0.06 FALSE
7 GTEx Brain Cerebellum HSD17B6 0.31 0.27 lasso 5 0.29 3.2e-09 -5.72 -5.1 2.8e-07 -0.02 0.09 0.85 FALSE
8 GTEx Brain Cortex SUOX 0.16 0.11 lasso 4 0.10 1.1e-03 -5.79 5.9 3.0e-09 -0.68 0.07 0.26 FALSE
9 GTEx Breast Mammary Tissue RPS26 0.29 0.05 enet 37 0.12 9.4e-07 -6.17 -7.6 3.4e-14 0.63 0.22 0.77 FALSE
10 GTEx Breast Mammary Tissue (Female) RPS26 0.20 0.11 lasso 3 0.10 6.6e-04 -5.79 -8.2 3.3e-16 0.84 0.01 0.87 TRUE
11 GTEx Cells Transformed fibroblasts PAN2 0.09 0.07 lasso 4 0.05 1.7e-04 4.67 5.1 3.0e-07 -0.24 0.90 0.00 FALSE
12 GTEx Colon Sigmoid SUOX 0.23 0.18 lasso 4 0.15 7.9e-06 -5.79 5.7 1.4e-08 -0.64 0.38 0.57 FALSE
13 GTEx Colon Sigmoid RP11-977G19.11 0.22 0.00 enet 33 0.04 1.5e-02 4.87 -6.6 4.6e-11 0.24 0.12 0.08 TRUE
14 GTEx Esophagus Gastroesophageal Junction SUOX 0.20 0.16 lasso 5 0.19 2.7e-07 -5.76 6.1 1.1e-09 -0.66 0.66 0.27 FALSE
15 GTEx Esophagus Gastroesophageal Junction WIBG 0.16 0.02 lasso 5 0.04 1.9e-02 0.86 5.5 4.7e-08 -0.35 0.04 0.24 FALSE
16 GTEx Esophagus Muscularis SUOX 0.24 0.19 enet 16 0.15 2.3e-09 -5.79 5.7 1.0e-08 -0.62 0.99 0.01 FALSE
17 GTEx Heart Atrial Appendage SUOX 0.09 0.10 enet 8 0.09 1.1e-04 -6.17 6.0 2.5e-09 -0.68 0.14 0.63 FALSE
18 GTEx Muscle Skeletal RAB5B 0.29 0.32 lasso 4 0.33 1.3e-33 -6.50 6.7 2.1e-11 -0.66 1.00 0.00 FALSE
19 GTEx Muscle Skeletal SUOX 0.11 0.04 lasso 7 0.04 4.4e-05 -5.79 6.3 2.9e-10 -0.67 0.29 0.63 FALSE
20 GTEx Muscle Skeletal AC034102.1 0.28 0.31 lasso 4 0.31 2.3e-31 -6.53 6.7 2.1e-11 -0.66 1.00 0.00 TRUE
21 GTEx Nerve Tibial RPS26 0.12 0.09 enet 7 0.11 3.0e-08 -5.95 -5.6 2.5e-08 0.58 0.96 0.03 FALSE
22 GTEx Nerve Tibial CNPY2 0.07 0.00 enet 21 0.00 3.2e-01 -5.95 5.2 2.0e-07 -0.39 0.09 0.14 FALSE
23 GTEx Prostate SUOX 0.22 0.04 enet 11 0.05 2.3e-02 -5.76 6.6 4.8e-11 -0.67 0.10 0.37 FALSE
24 GTEx Skin Not Sun Exposed Suprapubic SUOX 0.10 0.14 lasso 2 0.12 2.5e-07 -5.79 5.8 8.4e-09 -0.67 0.49 0.44 FALSE
25 GTEx Skin Sun Exposed Lower leg SUOX 0.23 0.30 lasso 3 0.29 1.9e-24 -5.79 6.0 2.1e-09 -0.68 1.00 0.00 FALSE
26 GTEx Spleen SUOX 0.34 0.31 enet 15 0.28 5.4e-08 -5.79 5.5 4.3e-08 -0.65 0.14 0.76 FALSE
27 GTEx Stomach SUOX 0.15 0.17 enet 8 0.09 6.7e-05 -5.79 5.4 6.5e-08 -0.65 0.68 0.24 FALSE
28 GTEx Stomach RPS26 0.16 0.08 enet 5 0.05 1.8e-03 -5.79 -5.7 1.3e-08 0.61 0.11 0.46 FALSE
29 GTEx Testis SUOX 0.27 0.18 lasso 14 0.18 1.4e-08 -5.79 6.3 2.4e-10 -0.67 0.74 0.25 FALSE
30 GTEx Thyroid SUOX 0.37 0.40 lasso 7 0.38 5.4e-31 -5.79 6.0 2.4e-09 -0.70 1.00 0.00 TRUE
31 GTEx Thyroid RP11-977G19.11 0.16 0.11 enet 20 0.13 3.5e-10 4.56 -5.7 9.8e-09 0.37 1.00 0.00 FALSE
32 GTEx Whole Blood RPS26 0.05 0.05 lasso 1 0.05 3.4e-05 -5.76 -5.8 8.2e-09 0.68 0.23 0.68 FALSE
33 METSIM Adipose IKZF4 0.04 0.04 enet 3 0.04 1.0e-06 -5.98 -6.0 1.5e-09 0.61 0.99 0.01 FALSE
34 METSIM Adipose RPS26 0.30 0.40 lasso 5 0.41 7.2e-66 -6.08 -6.2 7.7e-10 0.62 1.00 0.00 FALSE
35 YFS Blood SUOX 0.11 0.09 bslmm 269 0.09 3.4e-27 -5.76 5.5 3.7e-08 -0.65 1.00 0.00 FALSE
36 The Cancer Genome Atlas Bladder Urothelial Carcinoma RPS26 0.14 0.22 lasso 2 0.23 4.8e-19 -6.08 -6.1 7.9e-10 0.62 0.63 0.37 FALSE
37 The Cancer Genome Atlas Breast Invasive Carcinoma RPS26 0.30 0.44 enet 10 0.45 5.2e-104 -6.17 -6.3 2.2e-10 0.64 0.61 0.39 FALSE
38 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma RPS26 0.23 0.40 lasso 2 0.39 1.5e-20 -6.17 -6.4 1.8e-10 0.64 0.41 0.59 FALSE
39 The Cancer Genome Atlas Colon Adenocarcinoma RPS26 0.43 0.48 lasso 4 0.47 1.8e-30 -6.17 -6.5 1.0e-10 0.65 0.56 0.44 FALSE
40 The Cancer Genome Atlas Esophageal Carcinoma RPS26 0.19 0.13 lasso 5 0.11 2.4e-04 -6.17 -6.3 2.3e-10 0.65 0.02 0.95 FALSE
41 The Cancer Genome Atlas Glioblastoma Multiforme RPS26 0.41 0.38 enet 9 0.39 7.9e-13 -6.08 -6.2 5.6e-10 0.63 0.39 0.61 FALSE
42 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma RPS26 0.17 0.29 lasso 4 0.29 6.2e-33 -6.08 -6.2 5.7e-10 0.63 0.74 0.26 FALSE
43 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma RPS26 0.50 0.45 enet 13 0.52 1.4e-67 -6.08 -5.3 1.4e-07 0.62 0.79 0.21 FALSE
44 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma RPS26 0.27 0.38 enet 8 0.40 5.0e-24 -6.17 -6.3 3.7e-10 0.66 0.65 0.35 FALSE
45 The Cancer Genome Atlas Brain Lower Grade Glioma RPS26 0.31 0.53 enet 8 0.55 1.7e-74 -6.17 -6.3 3.9e-10 0.65 0.69 0.31 FALSE
46 The Cancer Genome Atlas Liver Hepatocellular Carcinoma RPS26 0.18 0.31 lasso 2 0.29 3.9e-14 -6.17 -6.2 7.6e-10 0.63 0.64 0.36 FALSE
47 The Cancer Genome Atlas Lung Adenocarcinoma RAB5B 0.03 0.02 enet 7 0.02 4.3e-03 -6.50 -6.0 2.0e-09 0.57 0.02 0.26 FALSE
48 The Cancer Genome Atlas Lung Adenocarcinoma RPS26 0.26 0.45 enet 9 0.47 3.6e-61 -6.17 -6.4 1.6e-10 0.66 0.65 0.35 FALSE
49 The Cancer Genome Atlas Lung Squamous Cell Carcinoma RPS26 0.22 0.31 lasso 3 0.31 1.6e-35 -6.17 -6.5 9.3e-11 0.65 0.61 0.39 TRUE
50 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma RPS26 0.30 0.20 lasso 4 0.24 3.9e-16 -6.17 -6.7 2.6e-11 0.67 0.11 0.89 FALSE
51 The Cancer Genome Atlas Pancreatic Adenocarcinoma ESYT1 0.16 0.02 blup 33 0.05 5.5e-03 2.26 -5.9 3.5e-09 0.30 0.01 0.67 TRUE
52 The Cancer Genome Atlas Pancreatic Adenocarcinoma RPS26 0.36 0.44 lasso 7 0.42 2.4e-19 -6.08 -6.0 1.6e-09 0.64 0.79 0.21 FALSE
53 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma RPS26 0.47 0.43 lasso 2 0.44 3.2e-19 -5.76 -6.0 1.9e-09 0.67 0.78 0.22 FALSE
54 The Cancer Genome Atlas Prostate Adenocarcinoma RPS26 0.33 0.52 enet 9 0.54 5.6e-66 -6.17 -6.3 2.8e-10 0.65 0.62 0.38 FALSE
55 The Cancer Genome Atlas Rectum Adenocarcinoma RPS26 0.24 0.18 lasso 2 0.20 1.9e-05 -6.17 -6.1 9.1e-10 0.66 0.06 0.49 FALSE
56 The Cancer Genome Atlas Soft Tissue Sarcoma RPS26 0.23 0.31 lasso 3 0.30 2.4e-18 -6.17 -6.3 3.4e-10 0.64 0.54 0.46 FALSE
57 The Cancer Genome Atlas Skin Cutaneous Melanoma RPS26 0.28 0.15 lasso 2 0.17 3.0e-05 -6.44 -6.4 1.4e-10 0.69 0.02 0.94 FALSE
58 The Cancer Genome Atlas Stomach Adenocarcinoma RPS26 0.19 0.32 lasso 5 0.34 2.0e-25 -6.08 -6.3 3.3e-10 0.63 0.75 0.25 FALSE
59 The Cancer Genome Atlas Testicular Germ Cell Tumors RPS26 0.46 0.64 lasso 4 0.65 8.5e-30 -6.17 -6.5 9.2e-11 0.64 0.35 0.65 FALSE
60 The Cancer Genome Atlas Thyroid Carcinoma RPS26 0.33 0.51 enet 19 0.50 7.3e-56 -6.17 -5.4 7.3e-08 0.64 0.62 0.38 FALSE
61 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma RPS26 0.17 0.19 lasso 4 0.18 1.3e-05 -6.17 -6.1 8.6e-10 0.67 0.04 0.93 FALSE