TWAS hub - WDR20

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1360	0.0350	5.6e-17	0.182	0.164	0.170	0.172	0.175	1.3e-21	1.6e-19	3.3e-20	2.0e-20	9.0e-21
2	METSIM	Adipose	0.0314	0.0138	3.6e-04	0.037	0.021	0.036	0.023	0.039	2.3e-06	3.4e-04	3.7e-06	1.9e-04	1.6e-06

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Impedance of arm (left)	10.0	46.1	48.5	-6.6	7.0
Severe depression (siblings)	8.7	9.7	10.8	-3.3	2.9
Impedance of arm (right)	8.6	40.2	43.2	-6.1	6.6
Worry too long after embarrassment	8.6	14.4	14.9	-3.7	3.9
Frequency of tiredness / lethargy in last 2 weeks	7.7	12.4	16.0	-3.0	4.0
Frequency of tenseness / restlessness in last 2 weeks	7.3	11.3	13.0	-3.1	3.6
Pulse rate, automated reading	7.2	23.2	25.0	5.0	-4.6
Impedance of whole body	7.2	36.5	41.3	-5.6	6.4
Maternal smoking around birth	6.8	9.8	11.9	-2.8	3.4
Mean Putamen Volume	6.5	7.4	9.0	3.0	-2.4
Supplements: Calcium	6.5	7.2	7.3	-2.6	2.7
Age started oral contraceptive pill	6.4	8.1	8.6	2.9	-2.7
Loud music exposure frequency	6.2	6.7	8.0	-2.3	2.8
Vitamin and mineral supplements	5.9	8.0	10.4	2.4	-3.2
Medication: Levothyroxine sodium	5.8	9.8	11.4	3.4	-2.9
Financial situation satisfaction	5.4	6.6	7.5	-2.4	2.7
Qualifications: nursing, teaching	5.2	8.1	9.9	-2.5	3.1
Neuroticism score	4.9	10.3	12.2	-2.9	3.5
Had other major operations	4.8	5.9	5.9	2.4	-2.4
Health satisfaction	4.6	6.0	7.5	-2.1	2.7
Neuroticism (Nagel 2018)	4.2	9.9	10.6	-3.0	3.3
Miserableness	4.2	7.4	8.6	-2.5	2.9
Multivitamins +/- minerals	4.1	5.2	6.4	-2.0	2.5
Fasting Glucose	3.8	4.5	5.3	2.3	-1.9
Sensitivity / hurt feelings	3.7	6.4	6.9	-2.4	2.6
Hair/balding pattern: Pattern 3	3.7	5.4	5.9	2.2	-2.4
Number of children fathered	3.7	4.1	4.6	1.9	-2.1
Number of operations (self-reported)	3.6	5.3	5.8	2.2	-2.4
Lupus	3.5	5.3	6.1	2.5	-2.1
Medication for hormone replacement therapy	3.5	3.9	5.2	1.7	-2.3
Nervous feelings	3.5	6.5	7.7	-2.3	2.8
Pulse wave Arterial Stiffness index	3.5	4.1	4.3	2.0	-2.1
Pulse wave peak to peak time	3.5	4.1	4.3	-2.0	2.1
Neuroticism	3.4	8.3	9.8	-2.6	3.1
Mood swings	3.4	6.1	7.6	-2.1	2.8
Basal cell carcinoma (self-reported)	3.3	4.0	4.7	1.8	-2.2
Had menopause	3.1	3.8	4.5	2.1	-1.8
Medication: Omeprazole (e.g. Zanprol)	3.1	3.8	4.4	-2.1	1.8
High blood pressure (siblings)	3.0	4.3	4.7	2.0	-2.2
Medication: Allopurinol	3.0	4.0	4.1	2.0	-2.0
Hair/balding pattern: Pattern 2	2.9	3.7	3.7	-1.9	1.9
Irritability	2.9	5.0	5.8	-2.4	2.0
Reaction Time	2.8	5.3	6.2	-2.1	2.5
Impedance of leg (left)	2.8	13.7	16.9	-3.2	4.1
Guilty feelings	2.8	4.2	5.4	-1.7	2.3
Type 2 Diabetes (T2D) (2012)	2.7	3.1	3.3	1.8	-1.7
Commuting to job workplace: Car/motor vehicle	2.7	3.0	3.3	-1.7	1.8
Arm fat-free mass (left)	2.6	13.0	13.6	3.7	-3.5
Frequency of depressed mood in last 2 weeks	2.5	3.5	4.3	-1.6	2.1
Trunk predicted mass	2.5	14.3	14.4	3.8	-3.8
Breastfed as a baby	2.5	3.1	3.5	1.9	-1.7
Arm predicted mass (left)	2.5	12.9	13.5	3.7	-3.5
Trunk fat-free mass	2.4	14.0	14.2	3.8	-3.7
Mouth/teeth dental problems: Dentures	2.4	4.1	4.7	1.9	-2.2
Seen doctor (GP) for nerves, anxiety, tension or depression	2.4	3.7	3.8	-1.9	1.9
Headache pain in last month	2.4	4.1	5.4	-1.6	2.3
Emphysema/chronic bronchitis	2.4	2.7	2.9	1.7	-1.6
Impedance of leg (right)	2.3	11.3	14.2	-2.9	3.8
Arm fat-free mass (right)	2.3	11.7	12.5	3.5	-3.3
Mean time to correctly identify matches	2.3	4.4	4.8	-2.0	2.2
Depressed Affect (Nagel 2018)	2.2	4.6	5.0	-2.1	2.2
Ever unenthusiastic/disinterested for a whole week	2.2	2.7	3.0	-1.5	1.7
Ever depressed for a whole week	2.2	2.8	3.1	-1.6	1.8
Number of incorrect matches in round	2.1	3.5	4.1	2.0	-1.7
Hearing difficulty/problems with background noise	2.1	3.4	3.6	-1.8	1.9
Arm predicted mass (right)	2.1	10.7	10.8	3.3	-3.3
High blood pressure (mother)	2.0	2.8	3.6	1.9	-1.4
Alzheimer’s Disease (including proxy)	1.9	2.8	3.0	-1.6	1.7
Rheumatoid Arthritis	1.9	2.6	3.0	1.7	-1.5
Lung FVC	1.9	9.6	11.8	2.7	-3.4
Financial difficulties in last 2 years	1.9	2.5	3.2	-1.3	1.8
Ever highly irritable/argumentative for 2 days	1.9	2.2	3.0	-1.7	1.2
Forced expiratory volume in 1-second (FEV1), predicted	1.9	4.0	4.1	-2.0	2.0
Breast Cancer	1.8	4.3	4.8	-1.9	2.2
Qualifications: A levels/AS levels or equivalent	1.8	3.9	4.2	-1.9	2.1
Whole body water mass	1.8	10.1	10.3	3.2	-3.2
Trunk fat percentage	1.7	6.8	8.1	-2.4	2.8
Fed-up feelings	1.7	3.1	4.4	-1.4	2.1
Whole body fat-free mass	1.7	9.5	9.6	3.1	-3.1
Ever had bowel cancer screening	1.7	1.9	2.1	1.4	-1.3
Blood Eosinophil Count	1.6	12.2	13.6	3.3	-3.7
Medication: Metformin	1.6	2.2	2.3	1.5	-1.5
Diabetes (father)	1.6	1.9	2.4	-1.2	1.6
Average weekly fortified wine intake	1.6	1.9	1.9	1.4	-1.4
Length of working week for main job	1.6	1.7	2.4	1.1	-1.5
Exposure to tobacco smoke outside home	1.6	2.2	2.5	-1.4	1.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.6	3.5	4.9	1.4	-2.2
Townsend deprivation index at recruitment	1.5	2.1	2.5	-1.3	1.6
Worrier / anxious feelings	1.5	2.8	3.9	-1.3	2.0
Gout (self-reported)	1.5	2.0	2.5	1.6	-1.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.5	1.7	1.8	1.3	-1.3
Lung FEV1/FVC ratio	1.4	7.2	7.6	2.8	-2.6
Noisy workplace	1.4	1.8	1.8	1.3	-1.3
Tense / ‘highly strung’	1.4	2.4	3.3	-1.2	1.8
Qualifications: College or University degree	1.4	4.4	4.9	-2.0	2.2
Neck or shoulder pain in last month	1.4	2.0	2.4	1.2	-1.6
Handedness (chirality/laterality): Left-handed	1.4	1.7	1.9	1.4	-1.3
Eye problems/disorders: Glaucoma	1.4	1.7	2.1	-1.1	1.5
Commuting to job workplace: Cycle	1.4	1.6	2.7	0.8	-1.6
BMI	1.3	7.7	8.8	2.6	-3.0
Exposure to tobacco smoke at home	1.3	1.4	1.9	1.4	-1.0
Blood Platelet Count	1.2	14.1	20.1	-2.9	4.5
Chronotype (morning person)	1.2	2.7	3.2	1.8	-1.5
Tinnitus: Yes, but not now, but have in the past	1.2	1.3	1.9	1.4	-0.8
Illnesses of siblings	1.2	1.7	1.9	-1.2	1.4
Happiness	1.2	1.4	1.6	-1.3	1.1
Glaucoma (self-reported)	1.2	1.4	1.6	-1.1	1.3
Chronic bronchitis/emphysema (mother)	1.2	1.4	1.5	-1.1	1.2
Medication: Omeprazole	1.2	1.4	1.7	-1.1	1.3
Suffer from ‘nerves’	1.2	1.8	2.7	-1.0	1.7
Average weekly beer plus cider intake	1.2	1.8	2.5	1.0	-1.6
Myopia	1.2	1.8	2.5	-1.0	1.6
Alzheimer’s Disease (in mother)	1.1	1.3	1.9	-1.4	0.9
Primary Biliary Cirrhosis	1.1	1.6	1.9	1.1	-1.4
Type 2 Diabetes (T2D) (2018)	1.1	2.0	2.3	1.3	-1.5
Past tobacco smoking	1.1	2.0	2.2	1.3	-1.5
Mouth/teeth dental problems: Bleeding gums	1.1	1.4	1.5	-1.1	1.2
Chest pain or discomfort	1.1	1.6	1.7	-1.2	1.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.1	1.2	1.4	-1.0	1.2
Basal metabolic rate	1.1	6.0	6.2	2.5	-2.4
Cholesterol lowering medication	1.1	1.6	2.2	-1.0	1.5
Heel T-Score	1.0	7.8	8.8	3.0	-2.6
Frequency of unenthusiasm / disinterest in last 2 weeks	1.0	1.3	2.0	-0.8	1.4
Bilateral oophorectomy (both ovaries removed)	1.0	1.2	1.5	1.0	-1.2
Ever taken oral contraceptive pill	1.0	1.1	1.3	-0.9	1.1
Tinnitus: Yes, now most or all of the time	1.0	1.1	1.6	-0.8	1.3
Ever had prostate specific antigen (PSA) test	1.0	1.1	1.5	0.8	-1.2
Pack years of smoking	1.0	1.4	1.5	1.2	-1.2
Worry (Nagel 2018)	0.9	1.9	2.4	-1.2	1.5
Ulcerative Colitis	0.9	1.3	1.4	-1.1	1.2
Hearing difficulty/problems: Yes	0.9	1.4	2.1	-0.9	1.4
Forced expiratory volume in 1-second (FEV1)	0.9	3.0	3.0	1.7	-1.7
Reason for reducing amount of alcohol drunk: Health precaution	0.9	1.1	1.4	1.2	-0.8
Age at first live birth	0.9	1.6	2.1	-1.5	1.1
Had major operations	0.9	1.0	1.1	0.9	-1.1
Medication: Paracetamol	0.9	1.4	2.3	1.5	-0.7
HbA1C	0.8	0.9	1.5	1.2	-0.4
Qualifications: None of the above	0.8	1.6	1.9	1.4	-1.2
Medication: Ibuprofen	0.8	1.0	1.1	1.0	-0.9
Alcohol intake frequency.	0.8	1.9	2.5	-1.2	1.6
Illnesses of father: Heart disease	0.8	1.2	1.2	1.1	-1.1
Schizophrenia vs Biploar Disorder	0.7	1.0	1.2	1.1	-0.9
Body Mass Index (BMI) (2010)	0.7	1.0	1.3	1.1	-0.8
HDL Cholesterol	0.7	1.1	1.1	-1.1	1.1
Schizophrenia (2014)	0.7	1.4	1.6	1.1	-1.3
Ever used hormone-replacement therapy (HRT)	0.7	0.9	1.5	0.5	-1.2
Qualifications: O levels/GCSEs or equivalent	0.7	1.0	1.1	-1.0	1.0
Number of full sisters	0.7	0.8	1.0	-0.8	1.0
Leg pain on walking	0.7	0.9	1.2	0.8	-1.1
Smoking status: Previous	0.7	1.1	1.3	-1.1	1.0
Average weekly red wine intake	0.7	1.1	1.2	1.0	-1.1
Mouth/teeth dental problems: Mouth ulcers	0.7	1.1	1.3	-1.1	1.0
Depression (Nagel 2018)	0.6	0.8	1.0	-1.0	0.8
Ulcerative Colitis (UC)	0.6	1.1	1.3	-1.0	1.1
Blood Red Count	0.6	5.9	7.7	-2.8	2.0
Average weekly spirits intake	0.6	0.7	1.1	0.5	-1.1
Supplements: Glucosamine	0.6	0.7	1.4	1.2	-0.3
Body mass index (BMI)	0.6	2.7	2.9	1.6	-1.7
Diabetes (self-reported)	0.6	0.9	1.4	0.7	-1.2
Hair/balding pattern: Pattern 4	0.6	1.4	1.6	-1.1	1.3
Hypothyroidism/myxoedema (self-reported)	0.6	1.3	1.5	1.2	-1.0
Forced vital capacity (FVC), Best measure	0.6	2.1	2.6	1.2	-1.6
Body fat percentage	0.6	2.3	2.7	-1.4	1.7
Medication for pain relief, constipation, heartburn	0.6	1.1	1.5	0.9	-1.2
Medication: Aspirin	0.6	0.8	0.8	-0.9	0.9
Illnesses of siblings: Diabetes	0.6	0.7	0.7	-0.8	0.8
Medication: Bendroflumethiazide	0.6	1.0	1.9	-0.3	1.4
Ever smoked	0.6	1.1	1.6	-0.8	1.3
Crohns Disease (2012)	0.5	0.9	1.6	-1.3	0.4
Triglycerides	0.5	0.8	1.0	0.7	-1.0
Relative age of first facial hair	0.5	1.1	1.4	-0.9	1.2
Systolic blood pressure, automated reading	0.5	1.5	2.0	1.0	-1.4
Leg fat-free mass (left)	0.5	2.7	2.7	1.6	-1.6
Relative age voice broke	0.5	0.7	0.8	0.9	-0.8
Leg predicted mass (left)	0.5	2.7	2.7	1.6	-1.6
Heart attack	0.5	0.6	0.7	-0.8	0.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.6	2.1	1.1	-1.4
Birth weight of first child	0.5	0.8	1.0	1.0	-0.8
Peak expiratory flow (PEF)	0.5	1.2	1.3	1.1	-1.0
Blood clot in the leg (DVT)	0.5	0.6	0.8	0.7	-0.9
Eye problems/disorders: None of the above	0.5	0.6	0.9	0.9	-0.6
Migraine (self-reported)	0.5	0.6	1.2	1.1	-0.2
Age at last live birth	0.5	0.7	0.7	-0.8	0.8
Leg fat-free mass (right)	0.5	2.5	2.5	1.6	-1.6
Loneliness, isolation	0.5	0.6	0.9	-0.6	1.0
Medication: Aspirin	0.5	0.7	0.8	-0.7	0.9
Mother’s age at death	0.5	0.6	0.8	0.9	-0.6
Medication: Lisinopril	0.5	0.6	1.0	-0.5	1.0
Diastolic blood pressure, automated reading	0.5	1.5	1.6	1.3	-1.2
Intelligence (Savage-Jansen 2018)	0.4	1.3	1.6	-1.3	1.0
Pack years adult smoking proportion	0.4	0.6	0.7	0.8	-0.8
Stomach or abdominal pain in last month	0.4	0.5	0.8	-0.5	0.9
Chronic bronchitis/emphysema (father)	0.4	0.4	0.5	-0.7	0.6
Trunk fat mass	0.4	1.7	2.2	-1.1	1.5
Forced vital capacity (FVC)	0.4	1.5	1.7	1.1	-1.3
Weight	0.4	1.9	2.1	1.5	-1.3
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	0.6	0.5	-0.8
Depression (self-reported)	0.4	0.5	0.9	-0.4	1.0
Prospective memory result	0.4	0.5	0.9	0.9	-0.4
Comparative body size at age 10	0.4	1.1	1.5	0.9	-1.2
Supplements: Vitamin C	0.4	0.5	0.6	-0.6	0.8
Arm fat percentage (left)	0.4	1.7	1.7	-1.3	1.3
Diabetes diagnosed by doctor	0.4	0.6	1.1	0.5	-1.0
Osteoporosis (self-reported)	0.4	0.5	0.5	0.7	-0.7
Medication: Gliclazide	0.4	0.4	0.6	0.8	-0.5
Leg predicted mass (right)	0.4	2.1	2.1	1.4	-1.4
Alcohol drinker status: Never	0.4	0.4	0.5	0.6	-0.7
Heart attack/myocardial infarction (self-reported)	0.4	0.5	0.6	-0.8	0.7
Deep venous thrombosis (DVT) (self-reported)	0.4	0.6	0.6	0.7	-0.8
Alzheimer’s Disease (in father)	0.3	0.4	0.6	-0.4	0.7
Ovarian Cancer	0.3	0.3	0.5	0.4	-0.7
Bipolar Disorder (2011)	0.3	0.3	0.3	0.5	-0.5
Tanning	0.3	4.1	4.6	-2.1	1.9
Sitting height	0.3	2.3	3.1	1.8	-1.3
Waist circumference	0.3	1.0	1.4	1.2	-0.8
Medication: Ramipril	0.3	0.4	0.5	0.5	-0.7
Lung cancer (father)	0.3	0.3	0.4	-0.5	0.6
Illnesses of mother	0.3	0.3	0.4	-0.6	0.6
Pulse wave reflection index	0.3	0.3	0.5	0.5	-0.7
Medication: Paracetamol	0.3	0.5	1.0	1.0	-0.2
Number of full brothers	0.3	0.4	0.4	-0.6	0.7
Wheeze or whistling in the chest in last year	0.3	0.5	0.7	-0.6	0.8
Comparative height size at age 10	0.3	1.9	2.4	-1.2	1.5
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.4	0.5	0.5	-0.7
Back pain experienced in last month	0.3	0.4	0.5	0.7	-0.6
Mineral and other dietary supplements	0.3	0.4	0.4	0.6	-0.7
Osteoarthritis (self-reported)	0.3	0.3	0.3	0.6	-0.6
Number of self-reported non-cancer illnesses	0.3	0.5	0.9	-0.3	0.9
Wears glasses or contact lenses	0.3	0.4	0.7	-0.9	0.3
Supplements: Fish oil (including cod liver oil)	0.3	0.4	0.4	-0.6	0.7
Pain experienced in last month	0.3	0.5	0.7	0.5	-0.9
Bipolar Disorder (2018)	0.2	0.3	0.5	-0.7	0.1
Irritable Bowel Disease (IBD)	0.2	0.4	0.4	-0.6	0.6
Major Depression (MDD)	0.2	0.2	0.3	-0.4	0.6
Verbal and Numeric Reasoning (VNR)	0.2	0.4	0.5	-0.6	0.7
Number of treatments/medications taken	0.2	0.4	0.6	-0.5	0.7
Angina	0.2	0.3	0.5	-0.2	0.7
Current tobacco smoking	0.2	0.4	0.5	0.7	-0.6
Age when periods started (menarche)	0.2	0.4	0.5	0.6	-0.7
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.4	0.6	-0.8	0.3
Serious illness, injury or assault to yourself	0.2	0.2	0.4	0.7	-0.2
Hayfever, allergic rhinitis or eczema	0.2	0.5	0.7	-0.8	0.6
Diverticular disease/diverticulitis (self-reported)	0.2	0.2	0.4	-0.2	0.6
Alcohol usually taken with meals	0.2	0.4	0.5	-0.7	0.5
Mouth/teeth dental problems	0.2	0.2	0.4	-0.2	0.6
Pain all over the body in last month	0.2	0.2	0.4	-0.1	0.6
Arm fat percentage (right)	0.2	0.7	0.8	-0.8	0.9
Pulse rate	0.2	0.4	0.7	0.8	-0.2
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.3	0.5	-0.7	0.1
Medication: Ventolin 100micrograms inhaler	0.2	0.3	0.5	0.7	-0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.2	0.3	-0.4	0.5
Shortness of breath walking on level ground	0.2	0.2	0.2	-0.5	0.4
Medication: Blood pressure	0.2	0.4	0.5	0.7	-0.5
Medication: Seretide 50 evohaler	0.2	0.2	0.3	-0.5	0.4
Heart disease (mother)	0.2	0.3	0.3	0.5	-0.6
Leg fat mass (right)	0.2	0.7	0.9	0.9	-0.8
Overall health rating	0.2	0.4	0.8	0.1	0.9
Commuting to job workplace: Walk	0.2	0.2	0.3	-0.3	0.6
Medication for cholesterol	0.2	0.3	0.3	-0.6	0.6
Breast cancer (self-reported)	0.2	0.3	0.4	-0.3	0.7
Smoking status: Current	0.2	0.3	0.3	0.6	-0.4
Pain type(s) experienced in last month: Hip pain	0.2	0.2	0.2	0.5	-0.5
High cholesterol (Self-reported)	0.2	0.3	0.5	0.7	-0.4
Unable to work because of sickness or disability	0.2	0.3	0.5	0.3	0.7
Alcohol drinker status: Previous	0.2	0.2	0.2	-0.5	0.4
Leg fat mass (left)	0.2	0.8	1.0	1.0	-0.8
Crohns Disease (2017)	0.1	0.2	0.2	0.3	-0.5
Age at First Birth	0.1	0.1	0.2	0.4	-0.3
LDL Cholesterol	0.1	0.1	0.3	0.5	0.0
Neuroticism (2016)	0.1	0.2	0.2	-0.3	0.5
Blood White Count	0.1	1.1	1.5	-1.2	0.8
Height	0.1	2.6	3.7	-1.2	1.9
Hypothyroidism (self reported)	0.1	0.2	0.2	0.5	-0.3
Hand grip strength (left)	0.1	0.3	0.3	-0.5	0.6
Eye problems/disorders: Diabetes related eye disease	0.1	0.1	0.1	0.1	-0.4
Supplements: Zinc	0.1	0.1	0.3	-0.1	0.5
Medication: Co-codamol	0.1	0.2	0.3	0.6	-0.1
Diabetes (mother)	0.1	0.1	0.1	-0.4	0.3
Taking other prescription medications	0.1	0.2	0.3	0.5	-0.3
Qualifications: CSEs or equivalent	0.1	0.1	0.1	0.4	-0.1
Medication: Atenolol	0.1	0.1	0.2	0.5	-0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.2	0.4	-0.6	0.2
Allergy	0.1	0.3	0.3	0.6	-0.4
Hayfever/allergic rhinitis (self-reported)	0.1	0.1	0.1	-0.1	0.4
Fluid intelligence score	0.1	0.3	0.3	0.6	-0.5
Hip circumference	0.1	0.5	0.5	0.7	-0.7
Alcohol intake versus 10 years previously	0.1	0.1	0.1	-0.4	0.3
Father’s age at death	0.1	0.1	0.2	0.0	0.5
Number of live births	0.1	0.1	0.2	0.4	0.0
Medication: Cholesterol lowering	0.1	0.2	0.4	0.1	-0.6
Medication: Lansoprazole	0.1	0.1	0.1	0.3	-0.2
Arm fat mass (right)	0.1	0.2	0.3	0.5	-0.5
Medication for cholesterol, blood pressure or diabetes	0.1	0.2	0.3	-0.5	0.4
Angina (self-reported)	0.1	0.1	0.3	-0.0	0.5
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.1	0.2	-0.4	0.0
Illness, injury, bereavement, stress in last 2 years	0.1	0.1	0.1	0.4	-0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.1	0.2	-0.4	0.2
Illnesses of father: None of the above (group 1)	0.1	0.1	0.2	0.4	-0.3
Hearing aid user	0.1	0.1	0.2	-0.5	0.0
Commuting to job workplace: Public transport	0.1	0.2	0.2	0.5	-0.4
Medication: Blood pressure	0.1	0.2	0.4	0.7	-0.2
Illnesses of father: High blood pressure	0.1	0.1	0.2	-0.5	-0.1
Bipolar Disorder or Schizophrenia	0.0	0.1	0.2	-0.5	-0.1
Schizophrenia (2018)	0.0	0.0	0.0	-0.0	-0.1
Prostate Cancer	0.0	0.0	0.0	-0.1	-0.1
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	-0.1
Waist Hip Ratio (WHR)	0.0	0.2	0.2	0.3	0.5
Systolic Blood Pressure	0.0	0.0	0.0	-0.2	0.1
Smoking Status	0.0	0.1	0.2	0.4	-0.1
Allergy or Eczema	0.0	0.0	0.0	-0.1	-0.1
Cardiovascular Disease	0.0	0.2	0.3	0.5	-0.2
Respiratory disease	0.0	0.1	0.2	0.1	0.4
Hair Pigment	0.0	1.2	1.9	0.7	-1.4
Other serious medical condition/disability diagnosed by doctor	0.0	0.0	0.0	0.1	0.1
Ever had hysterectomy (womb removed)	0.0	0.0	0.0	-0.1	0.1
Hand grip strength (right)	0.0	0.1	0.1	0.4	-0.1
High blood pressure	0.0	0.0	0.0	0.0	0.1
Medication: Simvastatin	0.0	0.0	0.0	0.1	-0.2
Time employed in main current job	0.0	0.0	0.0	-0.0	0.2
Falls in the last year	0.0	0.0	0.1	0.2	0.1
Asthma	0.0	0.0	0.1	0.0	0.3
Standing height	0.0	0.3	0.6	-0.1	0.8
Medication: Amlodipine	0.0	0.0	0.0	0.2	0.0
Birth weight	0.0	0.0	0.0	0.2	0.1
Leg fat percentage (right)	0.0	0.1	0.2	0.4	-0.2
Mouth/teeth dental problems: Loose teeth	0.0	0.0	0.0	0.0	0.0
Whole body fat mass	0.0	0.1	0.2	-0.3	0.4
Family relationship satisfaction	0.0	0.0	0.0	-0.1	-0.0
Knee pain experienced in last month	0.0	0.0	0.0	0.1	-0.1
Hypertension (Self-reported)	0.0	0.0	0.0	0.0	0.1
Long-standing illness, disability or infirmity	0.0	0.0	0.0	0.0	0.0
Friendships satisfaction	0.0	0.1	0.1	0.2	0.3
Eye problems/disorders: Cataract	0.0	0.0	0.0	-0.2	0.0
Asthma (self-reported)	0.0	0.0	0.1	0.2	0.2
Arm fat mass (left)	0.0	0.1	0.1	0.4	-0.2
Average weekly champagne plus white wine intake	0.0	0.1	0.1	0.4	-0.0
Medication: Atorvastatin	0.0	0.0	0.0	-0.2	-0.1
Leg fat percentage (left)	0.0	0.1	0.1	0.4	-0.1
Risk taking	0.0	0.0	0.1	-0.1	0.2
Fractured/broken bones in last 5 years	0.0	0.0	0.1	0.1	-0.3
Vascular/heart problems diagnosed by doctor	0.0	0.0	0.0	-0.2	0.1
Heart disease (siblings)	0.0	0.0	0.0	0.2	-0.2

Hub : Genes

WDR20

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Trait associations