[Hub]/) : Traits : Impedance of whole body :

chr22:30,914,473-32,995,751

Best TWAS P=1.22e-10 · Best GWAS P=4.61e-10 conditioned to 0.0161

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Esophagus Gastroesophageal Junction SFI1 0.15 0.07 lasso 3 0.06 3.7e-03 -6.1 6.4 1.6e-10 -0.93 0.02 0.88 FALSE
2 GTEx Esophagus Mucosa SFI1 0.13 0.11 lasso 6 0.10 3.9e-07 -5.0 5.2 2.1e-07 -0.80 0.83 0.17 FALSE
3 GTEx Esophagus Muscularis LIMK2 0.08 0.03 lasso 4 0.01 4.3e-02 -6.1 5.9 2.7e-09 -0.84 0.03 0.92 FALSE
4 GTEx Heart Left Ventricle SFI1 0.12 0.10 enet 20 0.07 2.3e-04 5.1 5.4 7.1e-08 -0.67 0.07 0.92 FALSE
5 GTEx Muscle Skeletal SFI1 0.13 0.09 enet 22 0.10 1.7e-10 5.1 6.4 1.2e-10 -0.70 0.44 0.56 TRUE
6 GTEx Nerve Tibial SFI1 0.23 0.06 enet 16 0.14 1.9e-10 -4.6 5.6 2.6e-08 -0.75 0.27 0.72 FALSE
7 GTEx Thyroid SFI1 0.12 0.10 lasso 12 0.11 1.4e-08 -5.0 5.4 6.8e-08 -0.79 0.49 0.51 FALSE
8 NTR Blood DEPDC5 0.02 0.02 lasso 5 0.01 2.4e-05 -6.0 6.2 4.5e-10 -0.60 0.00 1.00 FALSE
9 NTR Blood PISD 0.05 0.08 lasso 5 0.09 3.3e-27 -6.0 5.4 7.6e-08 -0.52 0.02 0.98 FALSE
10 YFS Blood PISD 0.36 0.32 lasso 9 0.35 5.1e-122 -6.0 5.7 1.6e-08 -0.64 0.01 0.99 FALSE
11 The Cancer Genome Atlas Colon Adenocarcinoma RNF185 0.08 0.05 blup 54 0.08 1.8e-05 -6.2 -5.4 7.2e-08 0.85 0.01 0.98 FALSE
12 The Cancer Genome Atlas Brain Lower Grade Glioma LIMK2 0.06 0.06 blup 47 0.06 9.3e-08 -5.0 5.8 5.6e-09 -0.91 0.07 0.93 FALSE
13 The Cancer Genome Atlas Prostate Adenocarcinoma RNF185 0.06 0.05 blup 54 0.05 4.7e-06 -6.0 -5.2 2.1e-07 0.82 0.00 0.99 FALSE
14 The Cancer Genome Atlas Rectum Adenocarcinoma RNF185 0.18 0.10 enet 6 0.12 9.7e-04 -6.0 -5.9 3.1e-09 0.95 0.00 0.86 FALSE
15 The Cancer Genome Atlas Thyroid Carcinoma RNF185 0.06 0.09 lasso 4 0.07 1.5e-07 -6.2 -6.2 6.2e-10 1.00 0.00 1.00 FALSE
16 The Cancer Genome Atlas Thyroid Carcinoma SELM 0.04 0.00 blup 54 0.01 4.8e-02 -4.2 5.3 1.2e-07 -0.68 0.02 0.63 FALSE