Hub : Genes

PISD

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.2000	0.0430	0.0e+00	0.269	0.267	0.279	0.267	0.278	9.9e-33	2.1e-32	4.0e-34	2.1e-32	6.2e-34
2	GTEx	Brain Cerebellum	0.4820	0.1000	9.1e-05	0.049	NA	0.070	NA	0.072	1.4e-02	NA	4.2e-03	NA	3.7e-03
3	GTEx	Brain Frontal Cortex BA9	0.1603	0.0792	4.2e-03	0.036	NA	0.029	NA	0.047	4.1e-02	NA	5.8e-02	NA	2.2e-02
4	GTEx	Colon Sigmoid	0.1870	0.0870	6.0e-03	-0.008	NA	-0.001	NA	-0.005	9.8e-01	NA	3.6e-01	NA	5.3e-01
5	GTEx	Nerve Tibial	0.1346	0.0524	8.4e-05	0.002	NA	0.014	NA	0.012	2.2e-01	NA	3.4e-02	NA	4.2e-02
6	GTEx	Whole Blood	0.0640	0.0290	3.6e-04	0.039	NA	0.048	NA	0.045	1.4e-04	NA	2.9e-05	NA	5.3e-05
7	NTR	Blood	0.0496	0.0132	0.0e+00	0.078	0.078	0.087	0.079	0.089	6.8e-24	7.0e-24	1.5e-26	3.9e-24	3.3e-27
8	YFS	Blood	0.3579	0.0494	0.0e+00	0.325	0.345	0.351	0.350	0.354	8.1e-110	4.2e-118	1.0e-120	2.5e-120	5.1e-122
9	TCGA	Colon Adenocarcinoma	0.0520	0.0310	3.3e-03	0.004	0.047	0.023	NA	0.015	1.8e-01	1.0e-03	1.6e-02	NA	4.3e-02
10	TCGA	Brain Lower Grade Glioma	0.0322	0.0212	3.3e-03	0.018	0.025	0.019	NA	0.018	3.5e-03	6.5e-04	2.7e-03	NA	3.1e-03
11	TCGA	Liver Hepatocellular Carcinoma	0.0640	0.0350	2.6e-03	0.038	0.047	0.028	NA	0.042	6.7e-03	2.9e-03	1.8e-02	NA	4.6e-03
12	TCGA	Lung Adenocarcinoma	0.0214	0.0142	7.4e-03	0.002	0.006	0.005	NA	0.002	1.9e-01	5.4e-02	7.2e-02	NA	1.6e-01
13	TCGA	Lung Squamous Cell Carcinoma	0.0289	0.0194	3.4e-03	0.004	0.022	0.010	NA	0.018	9.7e-02	1.3e-03	2.3e-02	NA	3.5e-03
14	TCGA	Prostate Adenocarcinoma	0.0578	0.0298	3.0e-05	0.010	0.035	0.035	NA	0.038	2.7e-02	1.3e-04	1.2e-04	NA	7.7e-05
15	TCGA	Thyroid Carcinoma	0.0580	0.0330	1.3e-04	0.049	0.042	0.032	NA	0.033	1.4e-05	5.4e-05	4.3e-04	NA	3.1e-04

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15
Bipolar Disorder (2018)	4.0	6.3	16.7	-3.0	-1.9	-3.4	-1.0	-2.5	0.0	1.2	-0.0	-1.8	-2.8	-3.4	-3.5	-2.6	-1.8	-4.1
Bipolar Disorder or Schizophrenia	2.1	5.0	16.4	-2.0	-3.2	-2.4	-2.7	-3.0	-2.7	-0.6	-1.7	-0.4	-1.3	-1.6	-2.6	-0.9	-0.6	-4.1
Depressed Affect (Nagel 2018)	1.8	3.8	7.2	-2.6	-1.6	-2.4	-0.0	-1.6	0.5	2.2	1.7	-2.3	-1.7	-2.7	-1.7	-2.1	-2.4	-1.9
Depression (Nagel 2018)	1.1	1.7	6.8	-1.7	-1.3	-2.6	0.1	-1.2	0.2	1.2	0.7	-1.5	-0.8	-1.4	-1.3	-1.4	-0.9	-1.4
Intelligence (Savage-Jansen 2018)	1.2	3.6	11.2	2.4	2.2	1.2	1.1	1.2	3.3	0.8	2.1	0.4	1.8	2.5	1.9	1.5	0.8	2.5
Neuroticism (Nagel 2018)	1.4	3.4	8.4	-2.0	0.1	-1.8	0.5	-0.4	1.7	2.9	2.8	-2.0	-1.7	-2.4	-1.2	-2.0	-2.3	-0.7
Schizophrenia (2018)	1.4	2.9	11.2	-0.2	-2.5	-0.3	-2.8	-1.7	-3.4	-1.8	-2.2	0.9	0.7	0.6	-0.5	0.9	0.8	-1.9
Schizophrenia vs Biploar Disorder	3.6	4.8	10.0	2.3	0.9	2.1	0.2	2.0	-0.3	-1.6	-0.9	2.6	2.9	2.9	3.0	3.2	1.9	2.6
Worry (Nagel 2018)	1.7	3.5	7.6	-2.5	-0.5	-1.9	-0.1	-0.4	1.9	2.8	2.7	-1.9	-1.6	-2.8	-1.3	-2.0	-2.1	-1.1
Alzheimer’s Disease (in mother)	0.4	0.4	1.5	0.2	0.4	0.2	0.2	0.8	-0.0	0.6	1.2	0.7	0.8	0.2	1.0	1.0	-0.1	0.8
Alzheimer’s Disease (in father)	3.3	3.6	7.2	1.9	0.1	0.9	-0.6	1.1	-1.1	-2.4	-2.0	2.4	2.4	2.4	1.9	2.4	2.7	1.4
Alzheimer’s Disease (including proxy)	1.0	1.4	4.0	1.1	0.3	0.6	-0.2	0.9	-0.5	-0.5	0.2	1.5	2.0	1.5	1.6	2.0	1.4	1.1
Crohns Disease (2017)	0.3	0.6	4.0	0.9	2.0	1.8	-0.4	-0.0	0.1	-0.0	0.0	-0.3	-0.7	0.4	-0.1	-0.2	-0.5	0.7
Irritable Bowel Disease (IBD)	0.4	0.9	2.5	0.6	1.5	0.9	-0.7	-0.4	0.7	0.6	0.4	-1.6	-1.3	0.2	-0.9	-1.1	-1.5	0.1
Ulcerative Colitis (UC)	0.6	1.2	4.0	0.2	0.7	-0.3	-0.9	-0.8	1.4	1.1	0.7	-2.0	-1.1	0.0	-1.2	-1.3	-1.8	-0.3
Major Depression (MDD)	0.1	0.1	0.5	-0.0	0.5	-0.4	-0.1	0.5	-0.7	0.4	0.4	-0.4	-0.3	-0.3	-0.3	-0.3	-0.3	-0.3
Reaction Time	2.3	4.4	22.7	-0.2	-1.7	0.5	-1.1	-1.0	-4.8	-3.4	-4.2	1.4	0.5	0.6	-0.2	0.9	1.9	-1.5
Verbal and Numeric Reasoning (VNR)	1.0	2.5	6.2	2.1	1.9	1.6	1.1	1.6	1.5	0.5	1.3	0.0	1.5	2.4	1.9	1.0	0.6	2.5
Breast Cancer	0.9	2.1	5.4	1.5	-0.8	1.1	0.1	0.2	-0.2	-1.5	-1.3	1.7	2.1	2.0	1.5	1.9	2.3	1.0
Ovarian Cancer	0.4	0.5	1.2	-0.5	0.2	-0.2	1.0	-1.1	-0.1	0.0	-0.1	-0.7	-1.0	-0.8	-1.0	-0.9	-0.4	-1.1
Prostate Cancer	0.5	0.7	3.5	-0.5	-0.1	-0.5	1.9	0.9	-0.1	-0.9	-0.9	1.0	0.4	-0.4	0.3	0.4	1.6	-0.2
Age at First Birth	5.8	8.5	14.6	3.0	1.2	3.1	0.2	3.3	-0.6	-2.1	-0.4	3.5	3.7	3.7	3.8	3.8	3.3	3.5
Bipolar Disorder (2011)	2.4	2.3	5.3	-2.0	-2.0	-2.3	-0.5	-1.7	-0.1	1.6	1.1	-1.2	-0.8	-1.7	-1.5	-1.2	-1.2	-2.1
Body Mass Index (BMI) (2010)	0.9	1.3	4.6	-0.0	-1.7	0.7	-0.3	-0.1	-1.9	-1.7	-2.2	1.0	1.1	0.3	0.6	0.8	1.1	-0.4
Coronary Artery Disease (CAD)	1.1	1.3	4.5	-1.7	-1.5	0.0	0.6	-1.5	-1.3	-0.1	-0.8	-0.4	-0.7	-2.1	-0.8	-0.9	0.1	-1.7
Crohns Disease (2012)	0.5	0.8	3.7	0.8	1.9	1.7	-0.5	0.0	-0.2	0.5	0.6	-0.6	-0.9	0.4	-0.3	-0.5	-1.0	0.6
Mean Putamen Volume	0.3	0.3	3.0	0.2	-0.4	-0.4	-1.7	-0.4	-0.8	-0.0	0.0	-0.2	-0.1	0.0	-0.3	0.1	-0.7	-0.4
Fasting Glucose	1.1	1.4	6.7	0.1	0.6	-0.8	0.5	0.5	2.6	1.9	2.3	-1.0	-0.4	-0.4	-0.4	-0.7	-1.1	0.2
HbA1C	1.2	1.3	3.2	-1.2	0.5	-1.8	1.0	-0.2	1.6	1.5	1.0	-0.8	-1.3	-1.6	-0.8	-1.0	-1.1	-0.3
HDL Cholesterol	0.6	1.0	5.5	1.2	2.4	1.9	0.0	0.5	-0.2	-0.2	0.1	0.3	-0.1	1.0	0.8	0.5	-0.1	1.6
LDL Cholesterol	1.2	2.0	4.6	-1.3	-0.7	-2.1	0.8	-1.0	0.7	1.2	0.3	-1.6	-1.6	-1.8	-1.8	-1.8	-1.3	-1.6
Lupus	0.6	1.0	1.8	1.2	0.9	0.9	-1.3	0.7	-1.3	-1.0	-1.2	1.2	0.3	0.8	0.5	0.9	0.9	0.8
Neuroticism (2016)	0.6	0.9	4.1	1.2	1.6	2.0	-0.3	1.1	-0.2	-0.5	-0.4	0.3	-0.2	0.8	0.7	0.5	-0.2	1.4
Primary Biliary Cirrhosis	0.4	0.6	1.8	0.4	0.1	0.7	0.2	0.3	0.3	0.5	1.2	0.6	1.2	0.7	1.4	1.3	0.1	1.0
Rheumatoid Arthritis	0.2	0.3	0.9	-0.3	-0.5	-0.1	-0.9	-0.1	-0.9	0.1	0.2	0.9	0.8	0.2	0.7	0.7	0.6	0.4
Schizophrenia (2014)	1.2	2.7	10.2	-1.4	-3.0	-0.6	-1.6	-1.9	-3.2	-1.3	-1.9	0.5	0.1	-0.6	-0.8	0.3	0.2	-2.4
Triglycerides	0.5	0.9	2.2	-1.2	-0.7	-1.4	0.5	0.1	1.1	1.5	1.3	-1.0	-0.3	-1.0	-0.4	-0.9	-0.7	-0.6
Type 2 Diabetes (T2D) (2012)	0.8	0.9	1.9	1.1	0.8	1.0	0.1	1.0	0.4	-0.4	0.4	1.0	1.3	1.3	1.4	1.2	0.6	1.3
Ulcerative Colitis	0.6	0.9	2.6	0.5	0.0	0.6	-1.6	-1.2	-0.8	0.0	-0.8	-1.6	-1.0	0.5	-1.1	-1.0	-1.4	-0.6
Blood Eosinophil Count	4.7	36.3	82.4	5.6	1.1	3.7	-2.5	4.2	-4.8	-8.9	-7.6	9.1	5.6	6.0	4.8	7.5	8.6	3.5
Blood Platelet Count	0.5	5.9	19.5	4.4	3.2	2.7	-2.3	1.1	-0.5	-1.7	-1.4	2.2	1.4	3.8	1.6	2.4	1.3	2.8
Blood Red Count	0.1	1.4	6.5	1.5	-0.9	0.9	-0.6	0.3	-1.6	-0.7	-1.3	-1.1	1.4	2.5	0.9	0.0	0.2	1.1
Blood White Count	1.4	10.0	31.0	-0.5	0.2	-2.4	-1.1	-1.1	2.2	5.6	5.0	-5.5	-2.2	-0.7	-2.3	-3.6	-5.2	-0.7
Heel T-Score	0.5	4.2	17.1	-1.6	-4.1	-0.1	0.6	-1.1	-3.0	-2.9	-3.2	1.3	1.4	0.0	0.3	0.8	2.7	-1.7
BMI	0.6	3.6	16.9	0.8	0.4	1.7	-1.3	-1.2	-4.1	-3.2	-4.1	1.4	-0.6	0.5	-0.3	0.6	0.7	-0.5
Height	0.5	10.1	22.4	1.8	-0.0	1.2	4.0	3.9	0.0	-1.5	0.1	3.5	4.7	3.2	4.4	3.5	4.7	3.9
Waist Hip Ratio (WHR)	1.4	6.3	28.4	-0.4	0.5	-0.6	3.1	2.3	5.3	3.6	5.0	-0.8	1.7	0.1	2.0	0.2	-0.1	2.3
Systolic Blood Pressure	1.3	6.6	19.7	0.9	3.9	0.5	1.8	0.3	4.4	2.3	1.9	-2.7	-3.7	-1.6	-2.6	-2.6	-3.6	-0.5
Smoking Status	0.8	2.0	5.1	-1.5	-0.1	-1.1	2.2	0.8	2.2	1.8	1.9	-1.2	-0.8	-1.9	-0.3	-0.9	-1.6	-0.4
Allergy or Eczema	2.9	7.6	16.8	2.0	-0.2	3.0	-0.3	1.7	-1.8	-2.4	-1.5	3.0	4.1	3.5	4.0	3.7	3.2	3.0
Cardiovascular Disease	0.1	0.3	1.1	-0.0	0.5	0.7	0.4	0.0	0.0	-0.6	-0.9	0.0	-1.1	-0.7	-0.7	-0.4	-0.4	-0.5
Hypothyroidism (self reported)	1.8	4.0	11.3	-2.8	-1.5	-2.2	-0.9	-1.7	0.1	1.0	-0.0	-1.0	-2.6	-3.4	-2.6	-2.1	-1.7	-2.8
Respiratory disease	1.3	2.8	10.1	0.2	-1.9	0.6	0.2	0.1	-0.7	-1.2	-0.4	2.0	3.2	1.5	2.6	2.5	2.3	1.1
Type 2 Diabetes (T2D) (2018)	1.2	2.2	5.4	1.8	0.9	1.6	-0.4	0.8	-0.5	-0.6	-0.1	1.5	2.1	2.3	2.0	2.2	1.5	1.6
Lung FEV1/FVC ratio	0.6	3.2	10.9	-3.3	-2.2	-2.0	0.9	-0.3	0.8	1.2	0.7	-0.9	-1.4	-3.3	-1.5	-1.6	-0.7	-2.4
Lung FVC	1.5	7.9	20.7	1.3	-1.1	2.3	1.4	1.8	-2.7	-4.5	-3.9	3.7	2.9	2.2	2.7	3.2	4.0	1.4
Neuroticism	1.0	2.3	6.8	-1.7	0.1	-1.3	0.8	-0.0	1.7	2.6	2.6	-1.5	-1.1	-2.0	-0.5	-1.3	-1.8	-0.2
Chronotype (morning person)	0.6	1.5	4.3	-1.2	-0.7	0.4	0.2	-1.3	-1.4	-1.0	-2.1	-0.9	-1.6	-1.1	-1.3	-1.3	-0.8	-1.5
Hair Pigment	0.1	3.0	9.4	1.0	1.7	0.5	1.2	1.6	2.4	2.1	3.1	0.1	1.8	1.1	2.2	0.9	0.0	2.6
Tanning	0.2	2.8	6.0	-1.6	-0.5	-1.1	0.5	-1.9	0.4	1.3	0.6	-2.2	-2.2	-1.7	-2.3	-1.9	-2.2	-2.4
Hand grip strength (left)	1.5	4.0	7.7	1.6	-0.2	1.7	1.7	1.9	-0.7	-2.7	-2.5	2.7	2.0	1.9	1.9	2.3	2.8	1.4
Number of treatments/medications taken	0.6	1.0	2.8	-1.5	-1.7	-0.5	1.5	0.8	0.5	0.1	0.4	1.1	1.1	-1.1	1.1	0.6	1.0	0.2
Average weekly spirits intake	1.6	2.0	4.8	-1.4	-0.5	-1.3	1.1	-1.0	2.2	1.3	0.9	-1.4	-1.5	-2.0	-1.5	-1.6	-1.5	-1.4
Sensitivity / hurt feelings	0.4	0.6	2.6	-0.4	0.6	-1.2	1.0	1.6	1.0	0.9	0.9	-0.1	0.0	-0.4	0.5	0.0	-0.4	0.8
Frequency of depressed mood in last 2 weeks	0.1	0.2	0.7	-0.5	-0.6	-0.7	0.9	0.1	0.8	0.1	-0.1	-0.2	0.3	-0.3	0.3	-0.0	0.2	-0.0
Hearing difficulty/problems: Yes	1.9	2.9	7.2	1.5	1.1	2.4	0.8	1.5	0.5	-0.2	0.7	1.2	2.2	2.2	2.7	2.1	1.3	2.7
Relative age of first facial hair	0.5	1.1	5.0	-0.3	0.4	1.3	2.2	0.4	0.7	0.4	0.7	1.0	1.2	-0.1	1.7	1.1	0.6	1.3
Other serious medical condition/disability diagnosed by doctor	1.2	1.6	4.2	-1.8	-0.4	-1.2	1.9	0.8	1.9	1.2	0.6	-0.9	-1.2	-2.0	-0.6	-1.4	-1.0	-0.5
Ever used hormone-replacement therapy (HRT)	0.5	0.7	4.8	-0.8	-0.6	-0.2	2.2	-0.2	-0.2	-0.1	0.5	1.0	0.8	-0.4	0.9	0.7	0.9	0.3
Ever had hysterectomy (womb removed)	0.4	0.4	1.8	-0.0	-0.6	0.1	-1.4	-0.3	-1.1	-1.0	-0.9	0.7	0.3	0.1	0.0	0.5	0.4	-0.4
Systolic blood pressure, automated reading	0.9	2.7	11.1	1.4	3.3	0.4	0.1	-0.5	1.9	0.9	0.2	-1.8	-2.7	-0.3	-2.0	-1.7	-2.2	-0.3
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	1.8	0.1	-0.1	-0.7	-0.6	0.0	0.6	0.8	1.3	-0.1	0.6	0.3	0.4	0.3	-0.2	0.3
Angina	0.3	0.4	0.7	-0.5	-0.8	0.6	0.8	-0.8	-0.7	-0.6	-0.8	-0.4	-0.4	-0.2	-0.4	-0.2	-0.1	-0.8
Medication for hormone replacement therapy	1.7	1.9	4.8	0.3	0.0	1.6	1.3	0.6	-0.7	-2.2	-1.4	2.1	1.3	0.7	1.5	1.7	2.2	0.7
Vitamin and mineral supplements	0.9	1.2	3.4	-0.5	-0.5	-0.6	-0.6	-1.8	0.9	0.5	0.0	-1.1	-1.3	-0.9	-1.7	-0.9	-1.4	-1.8
Supplements: Zinc	0.2	0.3	1.0	0.2	0.8	0.6	0.6	1.0	0.6	0.1	0.2	-0.6	-0.6	0.0	-0.2	-0.6	-0.2	0.3
Medication: Co-codamol	0.4	0.5	1.8	-0.2	-0.2	-0.3	1.3	0.8	0.6	0.3	1.1	0.2	0.9	0.4	0.9	0.5	0.5	0.8
Medication: Metformin	0.3	0.4	1.1	0.1	0.1	-0.6	-0.3	-0.8	-0.4	1.0	1.1	-1.0	-0.2	0.3	-0.5	-0.3	-1.0	-0.5
Diabetes (father)	0.3	0.4	1.1	0.0	-0.4	0.7	0.7	0.9	0.0	0.9	1.1	-0.4	0.7	0.6	0.8	0.0	-0.2	0.8
Diabetes (mother)	0.4	0.5	1.6	-0.4	-1.0	-1.1	1.3	-0.9	-0.7	-0.1	-0.3	0.1	-0.2	-0.2	-0.6	-0.2	-0.1	-1.0
Severe depression (siblings)	2.2	2.5	8.5	0.9	0.8	1.7	-0.6	0.4	-1.0	-2.6	-2.1	2.9	0.9	0.6	1.2	2.0	2.1	0.8
Pack years adult smoking proportion	1.6	2.5	5.5	-1.0	-1.5	-2.2	0.3	-2.2	0.4	0.9	0.6	-1.8	-1.6	-1.1	-2.3	-1.7	-1.5	-2.3
Impedance of leg (right)	1.0	4.8	24.3	-0.4	0.8	-1.1	1.0	1.2	4.2	4.2	4.9	-1.8	-0.1	-0.6	-0.1	-1.0	-1.6	0.9
Leg fat-free mass (left)	0.3	1.7	7.0	0.4	-0.0	0.9	0.3	0.5	-2.2	-2.4	-2.6	1.6	0.5	0.4	0.7	0.8	1.4	0.4
Trunk fat percentage	0.6	2.6	6.1	-0.9	1.0	-1.3	-0.5	-1.7	0.6	2.1	1.2	-2.0	-2.2	-1.6	-1.8	-2.0	-2.5	-1.0
Hand grip strength (right)	1.0	2.8	7.7	1.0	-0.4	0.4	1.6	1.6	-0.6	-2.3	-2.2	2.5	1.8	1.1	1.3	2.0	2.8	0.7
Townsend deprivation index at recruitment	0.3	0.4	2.0	0.4	0.7	-0.5	-1.4	0.2	0.5	0.2	-0.0	-0.8	-0.8	-0.2	-0.8	-0.8	-0.7	-0.1
Current tobacco smoking	1.7	2.8	8.0	-0.3	0.7	-0.9	2.4	1.3	2.8	2.5	2.8	-2.0	-0.7	-1.0	-0.3	-1.3	-1.8	0.4
Average weekly fortified wine intake	0.5	0.6	3.2	-0.1	0.5	0.4	-0.9	-0.1	0.9	1.5	1.8	-0.9	-0.2	-0.1	-0.2	-0.5	-0.7	0.3
Maternal smoking around birth	0.1	0.2	1.0	-0.1	0.4	-0.1	-0.0	-0.1	0.8	0.8	1.0	-0.3	-0.1	-0.4	-0.1	-0.2	-0.5	-0.1
Fed-up feelings	0.6	1.1	3.2	-1.5	-0.5	-1.1	-0.2	-1.1	-0.9	-0.1	-0.9	-0.2	-1.4	-1.8	-1.3	-0.9	-0.6	-1.6
Frequency of unenthusiasm / disinterest in last 2 weeks	1.7	2.3	6.1	-2.1	-1.7	-2.5	0.2	-2.2	-0.2	1.0	0.3	-1.3	-1.0	-1.8	-1.3	-1.4	-1.2	-1.9
Relative age voice broke	2.3	3.5	7.5	2.1	1.6	2.7	0.6	1.0	-1.7	-1.8	-1.4	1.8	1.9	2.2	2.3	2.1	1.6	2.2
Taking other prescription medications	0.8	1.3	3.2	-1.0	-1.3	0.0	1.6	1.2	0.1	0.4	1.1	1.2	1.8	-0.3	1.8	1.1	1.2	0.9
Age when periods started (menarche)	1.2	2.8	11.0	0.9	1.2	-0.5	0.9	-0.6	2.2	3.3	3.3	-2.2	-0.2	0.5	-0.0	-0.9	-2.2	1.2
Bilateral oophorectomy (both ovaries removed)	1.7	1.9	3.7	1.6	1.5	1.4	-0.4	1.1	1.0	-0.6	0.5	1.6	1.6	1.7	1.6	1.9	1.3	1.7
Heel bone mineral density (BMD) T-score, automated (left)	1.2	2.7	7.7	-0.8	-1.9	0.4	1.7	-0.4	-2.3	-2.6	-2.8	1.9	1.2	0.1	1.0	1.3	2.2	-0.5
Tinnitus: Yes, but not now, but have in the past	1.1	1.2	7.1	1.9	2.7	0.4	-0.8	0.6	-0.7	-1.1	-0.9	0.8	-0.7	1.1	-0.2	0.6	0.1	0.8
Qualifications: CSEs or equivalent	1.1	1.4	4.1	-2.0	-1.9	-1.8	0.2	-0.6	-0.7	0.2	-0.2	-0.2	-0.6	-1.8	-1.1	-0.6	-0.4	-2.0
Serious illness, injury or assault to yourself	5.9	7.2	14.0	-2.6	-0.3	-2.0	-0.1	-1.5	1.7	3.1	2.1	-3.7	-3.3	-3.4	-3.0	-3.6	-3.7	-2.4
High blood pressure	0.3	0.9	4.1	0.2	2.0	0.3	0.2	0.2	0.9	0.6	0.4	-0.9	-1.8	-0.6	-1.0	-1.0	-1.4	-0.1
Hayfever, allergic rhinitis or eczema	2.8	6.0	11.4	2.3	0.9	2.5	-0.5	2.5	-1.0	-1.8	-1.1	2.5	3.2	3.3	3.4	3.0	2.9	3.0
Multivitamins +/- minerals	0.2	0.3	1.0	-0.1	0.2	-0.2	0.1	1.0	0.0	0.3	0.9	0.6	0.7	-0.0	0.8	0.4	0.6	0.8
Stomach or abdominal pain in last month	0.3	0.4	1.4	-0.1	-0.5	-0.4	0.9	-0.7	1.2	0.7	0.8	0.1	0.7	0.2	0.3	0.5	0.2	-0.1
Supplements: Glucosamine	0.6	0.8	2.1	-0.4	-0.7	0.5	0.9	0.2	-0.9	-1.0	-0.6	1.0	1.3	0.4	1.4	1.0	1.1	0.7
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	4.6	-0.1	-0.4	-2.2	-0.3	-0.6	-0.0	0.5	0.3	-0.4	-0.2	-0.2	-0.8	-0.2	-0.4	-0.8
Medication: Atenolol	0.3	0.3	1.4	-0.2	-0.5	-1.0	0.8	1.0	1.2	0.4	0.4	-0.2	0.4	0.2	0.1	0.0	0.3	-0.0
Medication: Levothyroxine sodium	1.5	2.6	6.6	-2.3	-1.0	-1.9	-0.5	-0.7	1.2	2.0	1.6	-1.2	-1.3	-2.6	-1.4	-1.5	-1.6	-1.7
Sitting height	0.4	2.9	7.2	1.2	-0.2	0.5	2.0	2.1	-1.0	-2.2	-2.2	2.1	1.6	1.5	1.5	1.3	2.7	1.5
Chronic bronchitis/emphysema (father)	0.8	0.9	3.5	-1.4	-1.3	-1.1	1.1	0.2	0.4	1.1	1.9	0.3	0.9	-1.0	0.8	0.4	0.3	0.2
High blood pressure (mother)	0.3	0.5	1.8	0.1	0.6	0.1	0.4	0.4	1.2	1.2	1.3	-0.7	-0.4	-0.1	-0.3	-0.5	-0.7	0.1
Body mass index (BMI)	0.4	1.8	7.3	-0.6	-0.2	0.5	-0.1	-1.8	-2.7	-1.8	-2.7	0.3	-1.2	-0.8	-0.9	-0.4	-0.2	-1.3
Impedance of leg (left)	1.1	5.1	24.1	-0.6	0.3	-1.7	0.8	0.1	4.0	4.5	4.9	-2.4	-0.3	-0.7	-0.5	-1.3	-2.0	0.3
Leg predicted mass (left)	0.3	1.7	6.9	0.4	-0.1	0.9	0.4	0.5	-2.3	-2.4	-2.6	1.6	0.5	0.4	0.7	0.9	1.4	0.4
Trunk fat mass	0.2	0.8	1.9	-0.5	0.6	-0.8	-0.1	-1.1	-0.2	1.0	0.2	-1.1	-1.3	-0.9	-1.0	-1.2	-1.4	-0.4
Waist circumference	0.1	0.5	2.8	-0.9	-0.1	-0.4	1.7	-0.3	0.2	0.8	0.5	-0.5	-0.5	-0.9	-0.1	-0.7	-0.7	-0.0
Number of incorrect matches in round	0.3	0.6	2.3	0.8	1.1	0.4	-1.5	0.3	-1.1	-0.9	-1.0	0.7	-0.1	0.2	0.0	0.3	0.5	0.4
Past tobacco smoking	1.1	1.9	7.3	2.1	0.3	0.9	-0.3	0.7	-0.5	-1.1	-0.5	1.0	2.0	2.7	1.5	1.5	1.6	1.5
Alcohol usually taken with meals	0.7	1.2	4.6	-0.9	-2.0	-0.6	-0.5	-0.7	-0.7	-1.4	-2.1	-0.2	-0.2	-0.3	-1.0	-0.6	0.8	-1.7
Nervous feelings	1.0	1.8	4.6	-1.1	0.9	0.1	-1.2	-1.0	1.6	1.8	1.7	-0.7	-1.7	-2.2	-1.1	-1.0	-2.0	-0.8
Frequency of tenseness / restlessness in last 2 weeks	1.3	2.1	5.1	-2.2	-2.0	-2.1	1.8	-0.9	0.5	1.6	1.3	-1.4	-0.5	-1.7	-0.8	-1.3	-0.7	-1.4
Hearing difficulty/problems with background noise	1.0	1.7	4.8	1.0	1.5	1.9	1.1	1.2	0.2	-0.4	0.3	1.0	1.2	1.2	1.9	1.2	1.1	2.2
Hair/balding pattern: Pattern 2	0.8	1.0	5.7	-1.2	-0.4	-0.1	1.4	0.8	0.8	1.8	2.4	-0.5	0.3	-0.9	0.5	-0.2	-0.4	0.2
Had menopause	0.4	0.5	3.0	-0.3	-0.3	-0.5	0.2	-1.7	-1.0	-0.4	-0.9	-0.2	-0.7	-0.3	-0.8	-0.5	0.1	-0.9
Had other major operations	3.8	4.7	12.3	-2.9	-3.3	-3.1	-0.4	-2.8	-2.5	-0.5	-1.1	-0.6	-1.2	-2.2	-2.2	-1.4	-0.6	-3.5
Forced vital capacity (FVC)	2.0	7.7	19.3	0.4	-2.5	1.0	2.6	1.8	-2.4	-3.3	-2.5	3.8	3.8	1.9	3.2	3.3	4.4	1.5
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.4	4.1	-1.4	-2.0	-0.4	1.3	0.0	-1.6	-1.4	-1.6	1.1	0.8	-0.7	0.6	0.6	1.4	-0.7
Ever unenthusiastic/disinterested for a whole week	2.1	2.6	5.7	-1.9	-0.9	-1.8	-0.4	-1.8	0.5	1.2	0.4	-1.4	-2.0	-2.1	-2.1	-1.6	-2.0	-2.4
Qualifications: None of the above	0.7	1.4	4.4	-1.7	-1.0	-1.4	1.9	-1.4	1.1	0.6	0.2	-0.3	-0.7	-2.1	-0.7	-0.8	-0.7	-1.1
Financial difficulties in last 2 years	0.5	0.6	2.1	0.3	-1.4	0.0	-0.4	0.4	-1.2	-1.2	-1.1	0.1	0.7	1.0	0.5	0.0	1.0	0.5
Mouth/teeth dental problems	1.0	1.5	4.5	2.1	0.8	2.0	-1.4	1.7	0.4	-0.1	0.1	-0.1	0.9	1.9	0.8	0.5	0.5	1.4
Heart attack	0.5	0.7	2.4	0.4	-0.4	0.8	0.8	0.2	-1.5	-0.9	-1.1	0.6	0.8	0.9	0.9	0.7	0.4	0.7
Allergy	1.6	3.7	9.7	-1.5	-0.3	-1.2	0.4	-1.9	0.6	0.8	0.1	-2.0	-3.1	-2.4	-3.0	-2.7	-2.3	-2.5
Pain all over the body in last month	1.0	1.0	5.8	-0.4	0.9	-0.7	0.8	-0.1	2.4	1.6	2.0	-0.2	-0.0	-0.7	0.3	0.0	-0.5	0.5
Diabetes (self-reported)	0.5	0.7	3.0	-0.4	0.2	-1.1	-0.0	-0.6	1.0	1.6	1.7	-0.9	-0.2	-0.4	-0.5	-0.4	-0.9	-0.6
Hayfever/allergic rhinitis (self-reported)	0.6	0.8	4.8	0.4	0.6	2.2	0.2	0.9	-0.5	-0.9	-0.8	0.7	0.5	0.3	1.2	0.5	0.8	1.0
Medication: Ramipril	0.4	0.5	2.5	-1.6	-1.5	-0.9	0.1	0.3	-0.3	0.4	0.4	0.1	0.0	-1.0	-0.1	-0.3	-0.2	-0.6
Medication: Simvastatin	0.3	0.4	2.6	0.0	-0.0	0.1	1.6	1.2	0.3	-0.1	-0.6	0.6	0.6	0.0	0.7	0.5	0.3	0.5
Fluid intelligence score	0.3	0.5	2.2	0.6	0.6	0.3	1.5	0.5	1.0	0.6	0.9	-0.3	0.7	0.8	0.7	0.3	0.2	0.8
Illnesses of siblings	1.0	1.4	8.9	-1.4	-1.1	-3.0	-1.3	0.4	0.1	1.0	0.9	-0.5	-0.5	-1.5	-1.0	-0.7	-0.5	-1.2
Neuroticism score	0.3	0.7	2.0	-0.9	0.5	-0.5	0.3	-0.1	0.2	0.9	0.5	-0.9	-1.3	-1.4	-0.7	-1.0	-1.3	-0.3
Weight	0.2	1.1	5.2	-0.0	-0.3	0.5	0.8	-0.4	-2.2	-1.8	-2.3	1.0	0.1	0.1	0.2	0.3	0.9	-0.0
Impedance of arm (right)	1.4	6.7	23.3	-0.0	1.7	-2.4	-1.8	0.4	4.3	4.6	4.8	-2.9	-1.3	-0.9	-1.3	-1.9	-3.1	0.2
Arm fat percentage (right)	0.4	1.5	3.9	-0.5	0.7	-0.7	-1.1	-1.8	-1.2	0.2	-0.7	-0.9	-2.0	-1.2	-1.7	-1.3	-1.6	-1.4
Trunk fat-free mass	0.9	5.4	14.4	0.8	-1.3	1.7	1.8	1.4	-3.1	-3.8	-3.6	2.7	2.1	1.6	2.0	1.9	3.3	1.2
Hip circumference	0.3	1.2	4.6	-1.0	-0.8	-0.4	0.0	-1.4	-2.1	-0.5	-1.3	-0.5	-1.3	-0.9	-1.2	-1.0	-0.8	-1.2
Time employed in main current job	0.4	0.4	4.0	-0.4	0.1	0.0	2.0	0.5	0.0	0.2	0.5	0.7	0.4	-0.3	0.7	0.5	0.4	0.5
Alcohol intake versus 10 years previously	1.5	2.3	9.6	-2.3	-3.1	-2.8	-0.3	-1.0	-2.0	-0.4	-0.4	0.9	0.6	-1.4	-0.3	0.2	0.8	-1.8
Father’s age at death	2.1	2.8	9.2	0.5	0.5	-1.0	-1.1	-1.8	1.1	2.1	1.6	-3.0	-1.8	0.1	-2.2	-2.2	-2.3	-0.8
Worrier / anxious feelings	0.5	1.0	3.6	-0.9	0.4	-0.0	-0.9	-0.9	-0.3	0.3	-0.3	-0.7	-1.9	-1.5	-1.4	-1.2	-1.3	-1.2
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	0.9	-0.5	0.6	-0.3	0.0	-0.7	0.9	0.9	0.8	-0.6	-0.9	-0.9	-0.5	-0.7	-0.9	-0.3
Falls in the last year	1.4	2.0	4.7	-1.3	-1.2	-1.1	-0.3	-2.2	-0.7	0.9	0.0	-1.9	-1.4	-1.2	-1.7	-1.6	-1.6	-1.9
Hair/balding pattern: Pattern 3	1.6	2.4	5.7	0.2	2.3	-0.6	-1.1	-0.8	1.5	1.8	1.3	-1.7	-2.4	-1.0	-1.7	-1.6	-2.4	-0.6
Number of live births	2.5	3.5	9.9	-3.0	-3.2	-1.9	1.3	-1.9	-0.5	0.1	-0.6	-1.3	-1.2	-2.5	-1.8	-1.9	-0.6	-2.8
Forced expiratory volume in 1-second (FEV1)	1.5	5.1	13.2	-1.0	-3.3	0.1	2.6	1.3	-2.0	-2.6	-2.1	3.2	2.8	0.3	2.1	2.4	3.6	0.1
Pulse rate	0.2	0.3	2.3	-0.9	-0.6	-0.1	1.5	-0.3	0.5	0.1	-0.2	-0.0	-0.2	-0.8	-0.1	-0.2	-0.1	-0.6
Happiness	0.8	1.0	3.4	-0.8	-0.5	0.3	-1.8	-0.8	-1.6	-0.4	-0.9	-0.7	-1.1	-0.5	-1.1	-1.0	-0.5	-1.2
Noisy workplace	0.8	1.0	2.5	-1.5	-1.3	-1.1	0.7	0.8	0.1	-1.0	-0.8	1.4	0.2	-1.6	-0.1	0.5	1.0	-1.2
Qualifications: A levels/AS levels or equivalent	0.6	1.4	3.8	0.0	0.4	-0.8	-0.8	-0.6	1.9	1.7	1.7	-1.6	-1.0	-0.3	-1.1	-1.2	-1.5	-0.6
Serious illness, injury or assault of a close relative in last 2 years	0.9	1.1	3.2	-0.5	0.9	-0.4	-0.2	-0.6	1.3	1.6	1.8	-1.3	-1.1	-0.8	-0.8	-1.2	-1.2	-0.2
Mouth/teeth dental problems: Dentures	1.4	2.4	7.2	-2.7	-1.2	-2.6	1.7	-1.2	-0.2	1.2	0.9	-0.4	-1.0	-2.6	-1.0	-1.0	-1.1	-1.8
Asthma	2.3	4.6	11.8	1.8	-0.2	1.4	0.2	0.6	-1.3	-1.7	-0.9	2.7	3.4	2.6	3.0	3.1	2.9	2.1
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.8	2.1	-0.2	-1.2	-0.7	-1.4	-1.1	-0.8	-0.7	-0.9	-0.4	-0.8	-0.6	-1.3	-0.7	-0.2	-1.4
Medication: Cholesterol lowering	0.4	0.7	3.3	-0.1	-0.4	0.4	0.1	-0.1	-1.7	-1.3	-1.8	0.8	0.3	0.3	0.3	0.4	0.8	-0.1
Depression (self-reported)	0.6	0.8	5.6	-0.3	0.2	0.1	2.4	-0.0	2.0	0.8	0.7	-0.1	0.2	-0.4	0.4	0.2	-0.3	0.1
Medication: Lansoprazole	0.4	0.5	1.8	-0.2	0.3	-0.7	1.3	-0.0	0.8	1.3	1.1	-0.3	0.4	-0.1	0.5	0.2	-0.6	0.5
Prospective memory result	0.3	0.3	1.2	0.7	0.7	0.9	0.2	0.3	1.1	0.1	0.1	-0.7	-0.5	0.2	-0.2	-0.5	-0.5	0.5
Lung cancer (father)	1.5	1.8	3.7	-1.6	-0.6	-1.3	0.6	-0.6	1.2	1.6	1.7	-1.5	-1.2	-1.9	-1.2	-1.5	-1.5	-1.1
Illnesses of mother	0.4	0.5	1.7	-0.3	-0.9	-1.2	-0.5	0.5	-0.9	-0.9	-1.3	0.5	0.5	-0.1	0.1	0.2	1.1	-0.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.8	2.4	7.8	-1.5	-2.8	-1.2	2.1	1.0	-1.0	-1.4	-1.1	2.1	1.5	-0.8	0.9	1.2	2.2	-0.7
Pulse wave Arterial Stiffness index	0.6	0.7	2.4	0.5	0.8	0.8	0.2	1.2	0.7	0.2	0.9	0.7	1.0	0.4	1.4	0.8	0.3	1.5
Impedance of arm (left)	1.9	8.8	30.8	-0.2	1.9	-2.6	-1.8	0.2	5.0	5.3	5.5	-3.1	-1.6	-1.3	-1.6	-2.1	-3.4	0.1
Arm fat mass (right)	0.2	0.7	3.7	-0.0	0.3	0.1	-0.2	-1.1	-1.9	-1.0	-1.7	0.1	-0.9	-0.4	-0.7	-0.4	-0.3	-0.6
Trunk predicted mass	1.0	5.6	14.9	0.8	-1.3	1.7	1.8	1.5	-3.1	-3.9	-3.7	2.8	2.2	1.6	2.0	1.9	3.4	1.2
Standing height	0.4	3.7	10.4	1.1	-0.2	0.2	2.4	3.2	0.8	-0.2	0.6	1.5	2.8	1.9	2.6	1.6	2.5	2.8
Length of working week for main job	0.4	0.5	3.4	-0.2	-0.7	-0.0	-1.9	-0.4	-1.4	-0.5	-0.6	-0.1	-0.1	0.1	-0.3	0.0	-0.4	-0.7
Exposure to tobacco smoke at home	3.0	3.3	7.4	-2.4	-1.8	-2.4	-0.1	-2.3	0.4	1.5	1.0	-1.1	-1.6	-2.7	-2.1	-1.7	-1.3	-2.6
Breastfed as a baby	3.3	4.1	7.1	2.0	1.6	1.9	-0.1	2.3	-1.0	-1.7	-0.9	2.6	2.1	2.0	2.6	2.6	2.2	2.7
Tense / ‘highly strung’	0.5	0.9	2.3	-0.9	1.2	-0.3	0.3	0.1	0.8	1.2	0.8	-0.8	-1.4	-1.5	-0.8	-1.1	-1.1	-0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	1.1	-0.9	0.2	-1.0	0.8	0.9	1.0	0.6	0.5	0.1	-0.4	-1.0	0.2	-0.1	-0.4	0.2
Hair/balding pattern: Pattern 4	0.2	0.5	1.2	0.5	1.0	0.7	0.7	0.6	-0.2	-0.5	-0.5	1.1	0.3	-0.3	0.9	0.7	0.2	1.0
Birth weight of first child	1.4	2.5	7.8	-0.7	-1.2	0.7	0.6	0.5	-1.0	-2.1	-2.0	2.8	1.8	0.0	1.6	2.1	2.6	0.1
Peak expiratory flow (PEF)	2.0	4.6	10.9	-0.9	-3.2	-0.3	3.0	0.5	-1.8	-2.2	-2.0	2.9	2.8	0.5	2.0	2.4	3.3	-0.2
Pulse wave reflection index	0.3	0.3	2.1	0.3	0.4	0.4	-0.2	0.4	-0.2	0.4	1.4	0.1	0.5	0.4	0.8	0.3	0.0	1.0
Ever highly irritable/argumentative for 2 days	0.5	0.6	1.9	-1.1	-0.6	-0.7	1.2	1.4	-0.1	0.2	0.4	0.9	0.7	-0.9	1.0	0.6	0.6	0.1
Loud music exposure frequency	0.2	0.2	1.1	-0.3	-0.8	-0.5	0.0	0.3	-1.1	-0.5	-0.4	-0.1	-0.1	-0.3	-0.3	-0.2	0.1	-0.6
Qualifications: O levels/GCSEs or equivalent	1.3	2.1	5.1	-0.7	0.1	-1.3	-1.3	-1.1	1.3	2.2	2.3	-1.9	-1.2	-0.9	-1.4	-1.4	-2.1	-1.0
Mouth/teeth dental problems: Bleeding gums	1.2	1.5	6.8	0.5	0.5	0.4	-1.2	-1.4	-1.8	-1.8	-2.6	-0.2	-1.4	0.4	-1.4	-0.6	-0.1	-1.0
Blood clot in the leg (DVT)	1.6	2.1	4.2	1.3	-0.2	0.8	-0.5	1.4	-2.0	-2.0	-1.7	1.9	1.4	1.5	1.2	1.5	1.9	1.0
Medication: Paracetamol	0.5	0.8	3.3	-1.7	-1.8	-0.7	-0.1	-1.1	-0.3	-0.5	-0.1	0.5	0.4	-1.1	-0.0	0.4	0.3	-1.4
Headache pain in last month	2.0	3.5	11.3	-2.4	-3.0	-2.0	0.2	-3.0	-0.6	0.1	-0.8	-1.1	-1.0	-1.8	-2.1	-1.2	-1.1	-3.4
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	1.8	0.5	-0.8	0.0	-0.4	-0.5	-0.6	-0.2	0.4	0.6	1.3	0.9	0.8	1.0	0.8	0.2
Glaucoma (self-reported)	0.8	0.9	3.9	-0.1	1.2	0.1	0.2	0.8	1.9	1.4	2.0	-1.0	-0.4	-0.4	0.0	-0.5	-1.0	0.4
Gout (self-reported)	0.7	1.0	2.9	-0.5	-1.2	-0.6	0.9	1.0	1.1	1.0	1.7	-0.0	1.6	0.4	1.2	0.5	0.7	0.8
Hypothyroidism/myxoedema (self-reported)	1.9	3.6	12.6	-3.3	-2.1	-2.4	0.3	-0.7	0.6	1.3	0.6	-0.8	-1.8	-3.5	-1.9	-1.8	-1.2	-2.4
Medication: Amlodipine	1.5	2.2	5.9	-2.3	-1.1	-1.9	1.1	0.2	2.1	1.6	1.4	-0.8	-0.9	-2.4	-0.9	-1.1	-1.0	-1.4
Medication: Ventolin 100micrograms inhaler	0.7	0.9	3.0	-0.3	-1.0	-0.6	-0.2	-0.4	-1.0	0.5	1.1	1.1	1.7	0.3	1.4	1.5	0.5	0.5
Birth weight	4.4	9.6	17.7	3.1	0.1	3.1	-1.8	1.6	-2.6	-3.4	-3.0	3.3	3.7	4.2	3.4	3.6	3.9	2.9
Chronic bronchitis/emphysema (mother)	0.2	0.2	0.7	-0.1	0.6	0.4	-0.7	0.0	0.2	0.2	0.4	-0.3	-0.8	-0.6	-0.4	-0.5	-0.8	0.2
High blood pressure (siblings)	1.8	2.6	9.3	2.3	1.5	3.1	0.2	0.4	-0.9	-1.8	-1.5	1.4	0.9	2.3	1.4	1.4	1.2	1.8
Forced vital capacity (FVC), Best measure	1.2	4.3	11.0	0.1	-2.2	-0.1	2.1	1.6	-1.6	-2.3	-1.6	3.2	2.9	1.0	2.3	2.5	3.3	0.9
Body fat percentage	0.5	1.8	4.2	-0.8	0.6	-1.0	-0.5	-1.8	-0.1	1.4	0.5	-1.6	-2.0	-1.4	-1.7	-1.6	-2.1	-1.1
Leg fat percentage (right)	0.2	0.7	1.7	-0.6	0.5	-0.2	0.2	-1.2	-0.7	0.5	-0.1	-0.8	-1.3	-0.9	-1.0	-0.9	-1.2	-0.8
Arm fat-free mass (right)	0.7	3.4	8.8	0.0	-1.3	1.1	2.0	0.8	-2.4	-3.0	-3.0	2.2	1.6	0.7	1.5	1.4	2.7	0.6
Exposure to tobacco smoke outside home	1.7	2.3	4.9	-1.2	-1.6	-2.2	-1.4	-2.0	-1.3	0.4	-0.5	-1.2	-1.3	-1.2	-2.0	-1.4	-1.3	-2.2
Comparative body size at age 10	0.8	2.3	9.2	-1.3	-1.9	-0.0	0.1	-3.0	-0.7	-1.0	-2.0	-1.2	-1.4	-1.1	-1.7	-1.4	-0.7	-2.3
Number of full brothers	3.9	4.9	11.6	-3.4	-2.2	-3.1	1.1	-2.2	0.6	1.5	0.7	-1.3	-1.8	-3.3	-2.2	-1.7	-1.8	-3.2
Worry too long after embarrassment	0.4	0.7	5.6	0.4	2.4	0.5	-0.5	1.3	0.3	0.1	-0.0	-0.0	-1.3	-0.4	-0.3	-0.5	-0.6	0.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.8	2.8	-0.6	1.0	-1.2	0.9	-0.3	1.7	1.2	1.1	-0.3	-0.7	-0.8	-0.2	-0.2	-0.9	0.1
Wheeze or whistling in the chest in last year	0.5	1.0	4.2	-0.7	-1.6	-1.4	-0.3	-2.1	-1.9	0.2	-0.3	-0.7	0.2	-0.1	-0.4	-0.3	-0.4	-0.9
Number of children fathered	0.7	0.8	4.3	-1.5	-2.1	-1.5	0.6	-0.0	0.3	0.5	0.5	-0.6	0.4	-1.0	-0.1	-0.6	0.3	-0.5
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	1.3	0.3	1.1	0.2	-0.1	-0.0	0.3	-0.2	-0.1	-0.3	-0.8	-0.2	-0.6	-0.2	-0.7	-0.3
Age at first live birth	0.8	1.4	3.9	2.0	1.2	1.4	-0.5	1.1	0.2	-0.9	-0.8	1.0	0.7	1.8	1.1	1.0	0.8	1.7
Pulse wave peak to peak time	0.7	0.9	2.5	-0.5	-0.8	-0.9	-0.3	-1.2	-0.9	-0.3	-1.1	-0.7	-1.0	-0.5	-1.5	-0.9	-0.3	-1.6
Health satisfaction	2.1	2.8	6.2	-2.3	-1.4	-1.6	-1.1	-1.4	0.2	0.4	-0.5	-1.4	-2.0	-2.5	-2.1	-2.0	-1.3	-2.4
Shortness of breath walking on level ground	0.9	1.0	2.8	-0.1	0.9	0.1	-0.9	-0.4	1.7	0.7	0.5	-1.0	-1.6	-1.0	-1.4	-1.1	-1.4	-0.8
Qualifications: College or University degree	0.3	0.9	8.6	0.6	0.3	0.7	-2.9	-0.4	-0.1	-0.6	-0.9	-0.3	-0.8	0.4	-1.0	-0.6	-0.1	-0.5
Eye problems/disorders: None of the above	0.6	0.7	2.5	0.3	-0.0	0.5	-1.4	-0.2	-1.6	-1.2	-1.6	0.5	-0.4	0.2	-0.6	-0.0	0.6	-0.6
Mouth/teeth dental problems: Loose teeth	4.8	5.7	14.4	-3.4	-1.6	-3.8	1.5	-1.3	0.8	1.9	1.2	-1.8	-2.2	-3.7	-2.5	-2.4	-1.8	-3.1
Emphysema/chronic bronchitis	3.0	3.3	6.3	-2.3	-1.5	-1.3	0.8	-1.8	1.0	2.5	2.2	-2.2	-1.3	-2.2	-1.3	-1.8	-2.4	-1.5
Medication for pain relief, constipation, heartburn	0.8	1.4	4.7	1.6	2.2	-0.2	-0.5	0.6	1.2	1.8	1.9	-1.0	0.0	1.2	0.3	-0.2	-0.9	1.6
Neck or shoulder pain in last month	0.7	0.9	4.2	-0.6	-0.6	-1.0	-0.9	-2.0	-0.8	-0.2	-0.7	-0.7	-1.0	-0.6	-1.2	-1.0	-0.5	-1.1
Medication: Blood pressure	1.1	2.0	5.6	-0.9	0.9	-0.2	0.5	-0.1	1.7	1.4	0.7	-1.8	-2.4	-1.6	-1.6	-2.2	-2.0	-0.7
Angina (self-reported)	0.2	0.3	0.6	-0.4	-0.5	0.4	0.7	-0.7	-0.7	-0.4	-0.6	-0.3	-0.5	-0.3	-0.4	-0.2	-0.2	-0.7
Migraine (self-reported)	0.8	0.9	2.4	-1.5	-1.3	-1.4	1.0	0.3	1.2	0.8	1.2	0.4	0.9	-1.1	0.4	0.6	0.4	-0.7
Medication: Ibuprofen	0.3	0.3	1.3	0.3	-0.9	-0.4	-1.2	-0.3	-0.4	-0.8	-0.8	-0.1	-0.2	-0.0	-0.6	-0.3	0.2	-0.6
Medication: Allopurinol	0.8	1.0	3.2	-0.9	-0.6	-1.2	1.8	1.0	1.5	1.4	1.6	-0.7	0.5	-0.4	0.3	-0.3	-0.4	0.1
Medication: Omeprazole	0.6	0.7	2.2	-0.2	-0.0	1.3	0.6	0.0	-0.4	-0.3	0.2	1.4	1.2	0.0	1.5	1.3	0.9	0.8
Medication: Seretide 50 evohaler	0.8	0.9	3.0	0.1	-0.5	1.0	1.4	0.1	0.0	-0.0	0.0	0.6	1.6	1.0	1.7	1.2	0.5	1.1
Mean time to correctly identify matches	2.4	4.6	21.0	0.1	-1.4	1.1	-1.2	-1.3	-4.6	-3.6	-4.5	1.4	0.4	1.0	-0.2	0.8	2.0	-1.3
Heart disease (mother)	0.8	1.0	3.0	0.3	1.3	0.9	1.5	-1.7	-0.2	-0.7	-1.4	-0.5	-1.4	-0.1	-0.9	-0.5	-0.9	-0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	1.0	2.1	-0.7	-0.3	-1.2	-0.9	-1.0	0.6	0.9	0.6	-1.2	-1.2	-0.8	-1.4	-1.3	-0.9	-1.0
Whole body fat mass	0.1	0.6	1.5	-0.5	0.5	-0.3	0.2	-1.2	-1.1	0.3	-0.4	-0.7	-1.2	-0.8	-0.8	-0.9	-1.1	-0.5
Leg fat mass (right)	0.1	0.5	2.0	-0.4	0.3	-0.1	0.5	-1.0	-1.4	-0.3	-0.9	-0.2	-1.0	-0.6	-0.7	-0.5	-0.7	-0.6
Arm predicted mass (right)	0.6	2.9	6.8	0.0	-1.3	1.1	2.0	0.7	-2.1	-2.6	-2.6	2.1	1.6	0.7	1.5	1.3	2.5	0.7
Pulse rate, automated reading	0.5	1.6	6.2	-1.2	-0.2	-0.4	2.0	0.3	1.8	2.2	2.5	-0.6	0.3	-1.1	0.7	-0.3	-1.0	0.4
Alcohol intake frequency.	0.6	1.3	3.4	-1.2	-1.4	-1.2	0.7	-1.3	-1.6	-1.1	-1.5	0.3	-0.6	-1.2	-0.9	-0.2	0.0	-1.9
Comparative height size at age 10	0.6	3.1	8.9	1.1	0.6	0.9	1.6	3.0	0.9	-0.8	-0.2	1.7	2.2	1.7	2.3	1.5	2.7	2.5
Number of full sisters	0.6	0.8	4.4	-0.8	-2.1	-0.2	-0.4	-1.3	-1.1	-0.4	-0.3	-0.2	0.1	-0.5	-0.6	-0.1	0.1	-1.5
Suffer from ‘nerves’	1.2	1.9	8.1	-0.4	1.7	-1.2	0.4	0.2	2.8	2.1	2.1	-0.9	-1.1	-1.3	-0.4	-0.7	-1.7	0.4
Overall health rating	0.2	0.4	1.5	-1.2	-1.1	-0.5	0.6	0.4	0.3	0.2	0.3	0.2	0.1	-1.2	0.3	-0.1	0.0	-0.2
Chest pain or discomfort	2.2	3.1	8.6	-2.9	-1.8	-2.3	0.9	-2.4	-0.2	1.2	0.5	-1.1	-1.2	-2.8	-1.5	-1.5	-1.1	-2.4
Had major operations	1.8	2.1	7.3	-0.4	-0.5	-0.4	2.0	2.7	1.7	0.4	1.1	1.0	1.9	0.2	2.0	0.9	1.7	1.7
Age at last live birth	0.1	0.1	0.4	-0.0	-0.6	-0.4	0.6	-0.1	-0.1	-0.1	-0.3	0.0	-0.1	-0.0	-0.2	-0.3	0.0	-0.2
Family relationship satisfaction	0.1	0.1	0.4	-0.4	-0.1	0.4	-0.0	0.6	0.6	-0.1	0.3	0.1	0.2	-0.2	0.4	-0.1	0.5	0.3
Leg pain on walking	0.6	0.7	2.2	-0.9	-0.8	-1.5	0.5	-1.1	0.9	1.1	0.9	-0.8	-0.1	-0.5	-0.5	-0.6	-0.7	-0.8
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.4	2.2	-0.6	-0.8	-0.9	0.3	-1.1	-1.5	0.5	0.5	-0.0	0.2	-0.1	-0.1	0.3	-0.4	-0.7
Commuting to job workplace: Car/motor vehicle	0.3	0.4	1.5	-1.1	-1.2	-0.8	-0.0	-0.8	-0.6	0.1	0.2	-0.1	-0.1	-0.7	-0.4	-0.4	0.2	-0.8
Illness, injury, bereavement, stress in last 2 years	1.2	1.5	3.6	0.6	-0.7	1.3	-0.9	-0.2	-1.9	-1.4	-1.0	1.5	1.6	1.4	1.1	1.8	1.3	0.2
Medication: Aspirin	0.1	0.2	1.1	-0.1	-0.3	0.5	0.6	0.5	-0.4	-0.5	-1.0	-0.2	-0.2	0.1	-0.2	-0.1	0.1	-0.5
Supplements: Vitamin C	0.9	1.0	3.8	-0.2	-1.9	-0.8	1.4	-0.1	-1.5	-1.2	-1.7	-0.0	0.7	0.6	0.0	-0.3	1.3	-0.3
Knee pain experienced in last month	0.3	0.5	2.0	-0.5	0.1	-0.5	1.2	-0.1	0.7	1.1	1.4	-0.6	-0.2	-0.6	-0.1	-0.6	-0.6	0.2
Hypertension (Self-reported)	0.4	1.2	3.6	-0.3	1.6	-0.4	-0.2	-0.0	1.3	1.0	0.8	-1.1	-1.9	-1.1	-1.3	-1.3	-1.6	-0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.5	3.1	-1.0	-1.1	0.6	1.8	-0.5	-0.2	0.8	0.8	-0.1	0.4	-0.3	0.5	0.0	-0.0	-0.1
Illnesses of father: Heart disease	2.9	4.0	6.8	1.6	0.2	2.2	1.4	1.1	-1.1	-2.4	-2.1	2.5	2.3	2.2	2.5	2.6	2.3	1.8
Illnesses of siblings: Diabetes	0.4	0.5	1.2	-0.4	-0.9	1.1	1.1	-0.8	-0.7	-0.5	-0.4	0.7	0.8	0.2	0.7	0.6	1.0	0.1
Smoking status: Previous	1.0	1.5	4.8	-1.8	-0.5	-0.5	-0.7	-1.3	-0.4	0.4	-0.2	-0.6	-1.8	-2.2	-1.4	-1.2	-1.3	-1.6
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.0	2.5	-0.2	-1.3	-0.1	1.1	1.0	-0.4	-0.6	-0.5	1.1	1.6	0.4	1.5	0.8	1.6	1.0
Whole body fat-free mass	0.7	4.0	12.0	0.7	-0.9	1.5	1.2	1.0	-2.9	-3.4	-3.5	2.4	1.5	1.2	1.5	1.5	2.7	0.8
Leg fat-free mass (right)	0.3	1.6	7.5	0.3	-0.4	0.6	0.3	0.0	-2.3	-2.4	-2.7	1.3	0.4	0.4	0.5	0.7	1.2	0.1
Arm fat percentage (left)	0.4	1.6	4.2	-0.5	0.9	-0.8	-1.1	-1.8	-0.6	0.6	-0.2	-1.0	-2.0	-1.3	-1.8	-1.4	-1.7	-1.3
Average weekly red wine intake	1.1	1.6	3.7	-1.1	0.1	-1.8	0.0	-0.7	0.2	1.7	0.9	-1.9	-1.3	-1.0	-1.5	-1.7	-1.3	-1.3
Handedness (chirality/laterality): Left-handed	1.6	2.0	4.4	1.9	0.9	1.9	-2.1	0.4	-1.8	-1.5	-1.4	0.9	0.7	2.0	1.0	1.2	0.5	1.2
Mood swings	1.2	2.1	5.5	-2.2	-1.5	-1.6	-0.1	-1.2	-0.9	1.0	0.3	-1.2	-1.3	-2.3	-1.4	-1.4	-1.7	-1.9
Loneliness, isolation	0.1	0.2	0.7	0.4	0.2	-0.4	-0.9	-0.7	-0.6	0.2	0.1	-0.6	-0.3	0.2	-0.2	-0.4	-0.4	0.1
Long-standing illness, disability or infirmity	0.5	0.7	5.0	-1.2	-0.5	-0.1	2.2	0.7	0.3	0.9	0.9	-0.1	0.4	-0.9	0.8	-0.1	0.1	0.5
Ever had bowel cancer screening	0.5	0.5	2.8	0.7	0.6	-0.1	0.4	-0.2	1.7	1.0	0.9	-1.1	-0.2	0.6	-0.2	-0.5	-0.5	0.4
Diabetes diagnosed by doctor	0.2	0.4	2.4	-0.3	-0.1	-0.8	-0.3	0.1	0.7	1.2	1.5	-0.5	0.4	-0.0	0.1	0.0	-0.3	-0.2
Ever had stillbirth, spontaneous miscarriage or termination	1.0	1.1	2.3	-0.8	-0.5	-0.5	-0.3	-0.7	0.5	0.9	0.1	-1.1	-1.5	-1.5	-1.5	-1.3	-1.4	-1.4
Friendships satisfaction	0.4	0.5	3.5	0.1	0.6	0.2	-1.9	0.4	-1.0	-0.8	-0.9	0.4	-0.4	-0.3	-0.4	-0.2	0.7	-0.2
Qualifications: nursing, teaching	2.0	3.0	12.7	3.1	3.6	1.9	-2.5	2.0	0.3	-0.8	-0.4	0.5	-0.1	2.1	0.4	0.6	0.4	1.9
Commuting to job workplace: Walk	0.6	0.7	2.1	-0.5	0.3	-0.4	1.4	-0.2	1.1	1.5	1.1	-1.0	-0.4	-0.4	-0.1	-0.8	-1.0	0.3
Eye problems/disorders: Cataract	0.8	0.9	2.2	0.3	1.1	-1.3	-0.8	-0.0	1.1	1.4	1.4	-1.1	-0.8	-0.2	-0.6	-0.7	-1.5	0.1
Mouth/teeth dental problems: Mouth ulcers	0.6	1.0	2.6	0.2	0.3	1.1	1.4	0.0	0.5	-0.2	0.3	1.0	1.4	0.9	1.6	1.4	1.0	1.3
Medication for cholesterol	0.2	0.3	1.8	0.5	0.4	0.1	-1.3	0.2	0.4	0.6	0.8	0.0	0.5	0.7	0.5	0.4	-0.1	0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.1	0.7	-0.5	-0.4	-0.2	0.1	0.1	0.8	0.4	0.4	-0.2	0.1	-0.6	0.3	-0.2	-0.2	0.2
Back pain experienced in last month	1.3	1.9	5.8	-1.8	-2.1	-0.9	1.2	-2.4	-0.8	0.4	-0.2	-1.0	-1.1	-1.5	-1.4	-1.4	-0.6	-1.7
Mineral and other dietary supplements	0.2	0.3	1.1	1.1	0.7	0.3	-0.4	0.4	0.1	0.5	0.5	0.2	0.5	1.1	0.3	0.5	0.2	0.5
Breast cancer (self-reported)	2.5	3.0	7.4	-1.3	0.4	-1.5	-1.2	-1.5	0.8	1.9	1.3	-1.8	-2.3	-1.9	-2.2	-1.8	-2.7	-1.8
Asthma (self-reported)	2.2	4.3	10.4	1.4	-0.3	1.3	0.5	0.5	-1.5	-1.9	-1.1	2.9	3.2	2.3	2.9	3.0	3.0	1.9
Osteoporosis (self-reported)	3.5	4.3	9.0	-2.2	-1.0	-1.6	-0.1	-2.0	0.3	2.1	1.1	-2.6	-2.7	-2.4	-2.5	-2.7	-3.0	-2.2
Osteoarthritis (self-reported)	0.2	0.2	1.4	-0.8	-1.2	-0.0	0.6	-0.3	0.1	0.4	0.5	-0.2	0.6	-0.2	0.5	0.0	0.2	-0.1
Medication: Aspirin	0.2	0.2	1.0	-0.0	-0.5	0.5	0.8	0.8	-0.1	-0.6	-1.0	-0.1	0.2	0.3	0.1	0.1	0.3	-0.1
Medication: Gliclazide	1.9	2.2	5.1	-0.2	-0.3	-1.6	-0.9	-1.9	1.4	1.5	1.0	-2.1	-1.5	-0.5	-2.3	-1.8	-1.4	-1.7
Illnesses of father: None of the above (group 1)	2.0	2.5	6.5	-0.4	0.3	-1.0	-2.1	-0.8	0.0	1.1	0.6	-2.0	-2.4	-1.3	-2.6	-2.3	-2.0	-1.5
Smoking status: Current	1.2	2.0	5.6	-0.2	0.6	-0.7	2.3	1.2	2.4	2.1	2.3	-1.6	-0.5	-0.8	-0.1	-1.0	-1.5	0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.9	2.3	-1.5	-1.5	-0.5	1.4	-0.8	-0.1	-0.6	-0.7	0.5	-0.6	-1.3	-0.7	-0.2	0.2	-1.4
Whole body water mass	0.7	4.2	12.5	0.8	-0.8	1.5	1.1	1.0	-2.9	-3.5	-3.5	2.5	1.6	1.3	1.6	1.6	2.7	0.9
Leg predicted mass (right)	0.3	1.6	7.5	0.3	-0.5	0.6	0.3	0.0	-2.3	-2.4	-2.7	1.3	0.4	0.4	0.5	0.6	1.2	0.1
Arm fat mass (left)	0.2	0.7	3.5	-0.1	0.4	0.3	-0.2	-1.2	-1.9	-0.9	-1.6	0.1	-1.0	-0.4	-0.7	-0.4	-0.3	-0.7
Number of self-reported non-cancer illnesses	0.6	1.0	3.7	-0.9	-0.6	0.1	1.9	1.0	-0.5	-0.4	-0.1	1.6	1.1	-0.5	1.2	1.0	1.6	0.5
Average weekly champagne plus white wine intake	0.1	0.1	0.4	-0.1	-0.5	0.2	0.2	0.6	0.3	0.0	-0.0	-0.1	0.4	-0.0	0.2	-0.1	0.4	0.0
Miserableness	1.1	1.9	4.4	-0.8	-0.1	-0.7	-1.0	-1.3	-0.2	0.5	-0.4	-1.7	-2.1	-1.6	-2.0	-1.7	-2.1	-1.8
Guilty feelings	0.4	0.7	1.1	0.8	0.8	0.6	0.4	0.5	-0.9	-0.9	-0.9	0.9	0.6	1.0	0.8	0.8	1.0	1.0
Wears glasses or contact lenses	1.8	2.1	5.5	-1.2	0.6	-1.6	0.5	-1.0	2.3	1.8	1.6	-1.4	-1.5	-1.8	-1.4	-1.3	-1.4	-1.1
Ever taken oral contraceptive pill	0.5	0.5	2.0	0.1	-0.7	-0.1	1.4	-0.2	-0.7	-0.5	-0.2	0.9	0.9	0.6	0.7	1.0	0.8	0.2
Hearing aid user	0.3	0.3	1.4	-0.1	0.6	0.9	0.3	1.2	0.1	-0.3	0.2	0.7	0.2	-0.1	0.6	0.6	0.3	0.4
Mother’s age at death	0.9	1.1	5.5	1.5	0.5	0.9	-2.4	-0.8	-1.5	-1.0	-1.2	-0.2	-0.2	1.5	-0.6	-0.1	0.2	-0.0
Financial situation satisfaction	2.1	2.6	6.8	-1.4	-0.6	-1.3	-0.2	-1.4	0.6	1.3	0.3	-2.6	-2.1	-1.5	-2.0	-2.5	-2.2	-1.6
Tinnitus: Yes, now most or all of the time	0.4	0.4	2.1	-0.4	-1.1	-0.6	-0.2	0.2	-1.2	-0.8	-1.4	-0.1	0.3	-0.1	-0.0	-0.2	0.3	-0.5
Commuting to job workplace: Public transport	2.1	2.5	7.9	2.8	2.7	2.2	-2.3	1.7	0.5	-0.6	-0.5	0.1	0.1	2.1	0.5	0.4	0.5	1.9
Eye problems/disorders: Glaucoma	0.2	0.2	1.0	-0.1	0.4	0.1	0.1	0.6	1.0	0.5	1.0	-0.3	-0.0	-0.3	0.2	-0.2	-0.3	0.2
Medication: Blood pressure	0.1	0.1	0.5	0.0	-0.1	0.0	0.3	0.3	-0.4	-0.7	-0.6	0.7	0.2	0.0	0.1	0.5	0.4	-0.2
Pain type(s) experienced in last month: Hip pain	0.4	0.5	1.9	-0.9	-1.4	-0.5	1.2	-1.0	-0.9	0.2	-0.2	-0.7	0.0	-0.1	-0.3	-0.5	0.0	-0.7
Supplements: Fish oil (including cod liver oil)	0.2	0.3	0.8	-0.5	0.1	-0.6	0.3	-0.2	0.4	0.2	0.5	-0.6	-0.9	-0.9	-0.7	-0.8	-0.7	-0.2
High cholesterol (Self-reported)	0.6	1.1	5.9	1.0	0.4	0.5	0.1	-0.3	-2.2	-1.5	-2.4	0.4	-0.6	0.6	-0.8	-0.1	0.5	-0.5
Medication: Bendroflumethiazide	0.3	0.4	1.2	-0.1	0.8	0.1	-0.1	-0.1	0.1	1.0	1.0	-0.7	-0.6	-0.7	-0.3	-0.8	-1.1	0.1
Medication: Paracetamol	0.5	0.7	4.6	-1.4	-2.1	-0.3	-0.7	-0.9	-0.3	-0.4	0.2	0.4	0.7	-0.7	0.2	0.5	0.3	-1.1
Medication: Lisinopril	0.3	0.4	2.1	0.8	1.4	0.3	-0.5	0.1	0.8	0.3	0.1	-0.5	-0.8	0.2	-0.4	-0.4	-0.8	0.2
Medication: Atorvastatin	1.2	1.5	3.9	-1.5	-1.3	-1.8	0.0	-1.6	-0.4	-0.1	-0.5	-0.8	-1.3	-1.3	-1.8	-1.4	-0.1	-2.0
Illnesses of father: High blood pressure	0.3	0.4	0.9	-0.6	-0.2	-0.2	-0.1	-0.7	0.3	-0.1	-0.6	-0.7	-0.9	-0.8	-0.7	-0.7	-1.0	-0.8
Alcohol drinker status: Never	0.9	1.1	3.2	0.4	1.1	0.2	-1.0	-1.3	-0.5	-0.3	-0.8	-1.1	-1.8	0.1	-1.8	-1.0	-1.3	-1.2
Ever smoked	0.6	1.1	3.1	-1.5	-0.7	-0.7	0.7	-0.6	0.3	0.6	0.3	-1.0	-1.3	-1.8	-1.1	-1.2	-1.1	-1.2
Basal metabolic rate	0.6	3.2	10.9	0.6	-0.7	1.2	1.1	0.7	-2.9	-3.1	-3.3	2.1	1.1	0.9	1.2	1.2	2.2	0.6
Leg fat percentage (left)	0.3	1.2	3.9	-0.7	0.2	-0.6	0.0	-2.0	-0.8	0.7	-0.1	-1.2	-1.6	-1.0	-1.4	-1.3	-1.5	-1.2
Arm fat-free mass (left)	1.0	5.1	15.6	0.6	-1.1	1.7	1.6	0.7	-3.5	-3.9	-4.0	2.6	1.6	1.3	1.6	1.7	2.9	0.8
Number of operations (self-reported)	1.5	2.3	7.9	-2.7	-2.8	-2.7	0.9	-1.3	-0.9	0.5	0.6	0.3	0.2	-1.8	-0.6	-0.1	0.2	-2.0
Average weekly beer plus cider intake	0.7	1.0	5.7	-0.1	0.8	-0.0	-0.0	0.1	1.2	1.8	2.4	-0.9	-0.1	-0.3	0.4	-0.3	-1.3	0.7
Irritability	1.2	2.0	4.0	-1.3	0.9	-0.6	1.5	-0.1	0.3	2.0	1.5	-1.8	-2.0	-2.0	-1.2	-2.0	-1.6	-0.6
Risk taking	0.3	0.4	2.0	-0.5	-1.1	-0.2	0.7	-0.2	0.3	0.6	0.5	-1.4	0.1	-0.1	-0.1	-0.8	-0.4	-0.3
Ever had prostate specific antigen (PSA) test	2.2	2.5	7.6	2.2	2.3	2.0	-0.0	1.6	1.9	0.9	1.5	0.2	0.7	1.7	1.4	0.6	0.5	2.8
Fractured/broken bones in last 5 years	0.1	0.2	0.8	0.5	0.5	0.3	0.1	0.9	0.1	-0.4	-0.5	0.4	-0.0	0.1	0.3	0.2	0.0	0.5
Age started oral contraceptive pill	0.1	0.2	0.8	0.4	-0.0	-0.1	-0.7	-0.9	0.4	-0.2	-0.1	0.5	-0.1	0.1	-0.4	0.1	0.4	-0.3
Diastolic blood pressure, automated reading	0.9	2.7	9.8	-0.5	1.8	-0.3	0.9	-0.5	3.1	2.1	1.7	-1.6	-2.0	-1.7	-1.3	-1.6	-2.2	-0.3
Ever depressed for a whole week	0.4	0.5	1.9	-1.2	-0.3	0.1	0.8	0.4	1.4	0.2	0.4	0.1	-0.4	-1.3	-0.3	-0.1	-0.2	-0.9
Unable to work because of sickness or disability	0.7	0.9	3.9	-1.2	-0.8	-0.4	1.8	0.5	2.0	0.8	1.0	0.1	0.4	-1.1	0.4	0.1	-0.1	-0.2
Commuting to job workplace: Cycle	0.7	0.8	1.9	1.4	0.5	1.1	-1.2	0.0	-0.4	-1.4	-1.1	0.5	0.5	1.3	0.3	0.6	1.0	0.3
Myopia	0.7	1.0	4.8	1.0	2.2	1.5	-1.1	0.7	-0.5	0.6	0.4	-0.8	-1.2	0.1	-0.4	-0.6	-1.1	0.5
Vascular/heart problems diagnosed by doctor	0.4	1.0	4.2	-0.2	-2.0	-0.3	-0.5	-0.3	-1.0	-0.8	-0.5	1.0	1.7	0.6	0.9	1.0	1.4	-0.1
Cholesterol lowering medication	0.7	1.0	3.7	-1.2	-1.9	-1.3	1.8	-0.3	-0.3	-0.4	-0.9	-0.2	-0.0	-1.0	-0.6	-0.5	0.2	-1.3
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	1.9	-0.4	0.1	1.4	0.7	-0.3	-0.6	0.1	0.3	0.7	0.6	-0.2	1.0	0.8	0.3	0.4
Pain experienced in last month	1.3	2.2	5.8	2.1	2.4	1.4	-1.0	2.3	0.6	-0.2	0.0	0.9	1.0	1.7	1.6	1.3	0.7	2.1
Supplements: Calcium	0.4	0.5	3.6	-0.7	-0.6	0.1	-0.0	-0.6	-1.9	-0.8	-0.6	0.7	0.5	-0.1	0.6	0.6	0.3	-0.0
Basal cell carcinoma (self-reported)	0.4	0.5	1.9	-0.6	-1.1	-0.1	1.0	0.4	-1.4	-0.8	-0.6	0.6	0.5	-0.2	0.4	0.4	0.8	-0.0
Heart attack/myocardial infarction (self-reported)	0.6	0.8	2.7	0.4	-0.6	0.8	0.9	0.4	-1.6	-1.0	-1.2	0.8	1.0	0.9	1.1	0.9	0.7	0.7
Deep venous thrombosis (DVT) (self-reported)	2.1	2.7	5.7	1.4	-0.2	0.9	-0.3	1.5	-2.2	-2.4	-2.0	2.1	1.6	1.8	1.3	1.7	2.2	1.0
Heart disease (siblings)	0.8	1.0	2.7	-0.5	0.3	0.0	1.2	-1.7	1.2	0.2	-0.2	-0.9	-1.5	-1.0	-1.1	-0.9	-1.5	-0.9
Alcohol drinker status: Previous	3.0	3.4	7.6	-2.3	-0.9	-2.3	1.0	-1.8	0.7	1.5	1.0	-1.8	-1.9	-2.8	-2.0	-2.0	-2.0	-2.3
Pack years of smoking	1.5	2.2	5.0	-0.6	-0.9	-1.9	0.7	-2.0	0.7	1.1	0.7	-1.9	-1.6	-0.9	-2.2	-1.7	-1.5	-2.0
Impedance of whole body	1.6	8.0	32.0	-0.7	1.1	-2.7	-0.9	0.2	4.8	5.4	5.7	-3.0	-1.2	-1.3	-1.3	-1.9	-3.1	0.1
Leg fat mass (left)	0.2	0.6	2.6	-0.4	0.2	-0.1	0.3	-1.3	-1.6	-0.3	-0.9	-0.3	-1.0	-0.6	-0.8	-0.6	-0.7	-0.7
Arm predicted mass (left)	0.9	4.4	13.8	0.4	-1.3	1.3	1.5	0.5	-3.5	-3.6	-3.7	2.4	1.5	1.1	1.4	1.5	2.8	0.5