Hub : Genes

PISD

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.2000 0.0430 0.0e+00 0.269 0.267 0.279 0.267 0.278 9.9e-33 2.1e-32 4.0e-34 2.1e-32 6.2e-34
2 GTEx Brain Cerebellum 0.4820 0.1000 9.1e-05 0.049 NA 0.070 NA 0.072 1.4e-02 NA 4.2e-03 NA 3.7e-03
3 GTEx Brain Frontal Cortex BA9 0.1603 0.0792 4.2e-03 0.036 NA 0.029 NA 0.047 4.1e-02 NA 5.8e-02 NA 2.2e-02
4 GTEx Colon Sigmoid 0.1870 0.0870 6.0e-03 -0.008 NA -0.001 NA -0.005 9.8e-01 NA 3.6e-01 NA 5.3e-01
5 GTEx Nerve Tibial 0.1346 0.0524 8.4e-05 0.002 NA 0.014 NA 0.012 2.2e-01 NA 3.4e-02 NA 4.2e-02
6 GTEx Whole Blood 0.0640 0.0290 3.6e-04 0.039 NA 0.048 NA 0.045 1.4e-04 NA 2.9e-05 NA 5.3e-05
7 NTR Blood 0.0496 0.0132 0.0e+00 0.078 0.078 0.087 0.079 0.089 6.8e-24 7.0e-24 1.5e-26 3.9e-24 3.3e-27
8 YFS Blood 0.3579 0.0494 0.0e+00 0.325 0.345 0.351 0.350 0.354 8.1e-110 4.2e-118 1.0e-120 2.5e-120 5.1e-122
9 TCGA Colon Adenocarcinoma 0.0520 0.0310 3.3e-03 0.004 0.047 0.023 NA 0.015 1.8e-01 1.0e-03 1.6e-02 NA 4.3e-02
10 TCGA Brain Lower Grade Glioma 0.0322 0.0212 3.3e-03 0.018 0.025 0.019 NA 0.018 3.5e-03 6.5e-04 2.7e-03 NA 3.1e-03
11 TCGA Liver Hepatocellular Carcinoma 0.0640 0.0350 2.6e-03 0.038 0.047 0.028 NA 0.042 6.7e-03 2.9e-03 1.8e-02 NA 4.6e-03
12 TCGA Lung Adenocarcinoma 0.0214 0.0142 7.4e-03 0.002 0.006 0.005 NA 0.002 1.9e-01 5.4e-02 7.2e-02 NA 1.6e-01
13 TCGA Lung Squamous Cell Carcinoma 0.0289 0.0194 3.4e-03 0.004 0.022 0.010 NA 0.018 9.7e-02 1.3e-03 2.3e-02 NA 3.5e-03
14 TCGA Prostate Adenocarcinoma 0.0578 0.0298 3.0e-05 0.010 0.035 0.035 NA 0.038 2.7e-02 1.3e-04 1.2e-04 NA 7.7e-05
15 TCGA Thyroid Carcinoma 0.0580 0.0330 1.3e-04 0.049 0.042 0.032 NA 0.033 1.4e-05 5.4e-05 4.3e-04 NA 3.1e-04

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Bipolar Disorder (2018) 4.0 6.3 16.7 -3.0 -1.9 -3.4 -1.0 -2.5 0.0 1.2 -0.0 -1.8 -2.8 -3.4 -3.5 -2.6 -1.8 -4.1
Bipolar Disorder or Schizophrenia 2.1 5.0 16.4 -2.0 -3.2 -2.4 -2.7 -3.0 -2.7 -0.6 -1.7 -0.4 -1.3 -1.6 -2.6 -0.9 -0.6 -4.1
Depressed Affect (Nagel 2018) 1.8 3.8 7.2 -2.6 -1.6 -2.4 -0.0 -1.6 0.5 2.2 1.7 -2.3 -1.7 -2.7 -1.7 -2.1 -2.4 -1.9
Depression (Nagel 2018) 1.1 1.7 6.8 -1.7 -1.3 -2.6 0.1 -1.2 0.2 1.2 0.7 -1.5 -0.8 -1.4 -1.3 -1.4 -0.9 -1.4
Intelligence (Savage-Jansen 2018) 1.2 3.6 11.2 2.4 2.2 1.2 1.1 1.2 3.3 0.8 2.1 0.4 1.8 2.5 1.9 1.5 0.8 2.5
Neuroticism (Nagel 2018) 1.4 3.4 8.4 -2.0 0.1 -1.8 0.5 -0.4 1.7 2.9 2.8 -2.0 -1.7 -2.4 -1.2 -2.0 -2.3 -0.7
Schizophrenia (2018) 1.4 2.9 11.2 -0.2 -2.5 -0.3 -2.8 -1.7 -3.4 -1.8 -2.2 0.9 0.7 0.6 -0.5 0.9 0.8 -1.9
Schizophrenia vs Biploar Disorder 3.6 4.8 10.0 2.3 0.9 2.1 0.2 2.0 -0.3 -1.6 -0.9 2.6 2.9 2.9 3.0 3.2 1.9 2.6
Worry (Nagel 2018) 1.7 3.5 7.6 -2.5 -0.5 -1.9 -0.1 -0.4 1.9 2.8 2.7 -1.9 -1.6 -2.8 -1.3 -2.0 -2.1 -1.1
Alzheimer’s Disease (in mother) 0.4 0.4 1.5 0.2 0.4 0.2 0.2 0.8 -0.0 0.6 1.2 0.7 0.8 0.2 1.0 1.0 -0.1 0.8
Alzheimer’s Disease (in father) 3.3 3.6 7.2 1.9 0.1 0.9 -0.6 1.1 -1.1 -2.4 -2.0 2.4 2.4 2.4 1.9 2.4 2.7 1.4
Alzheimer’s Disease (including proxy) 1.0 1.4 4.0 1.1 0.3 0.6 -0.2 0.9 -0.5 -0.5 0.2 1.5 2.0 1.5 1.6 2.0 1.4 1.1
Crohns Disease (2017) 0.3 0.6 4.0 0.9 2.0 1.8 -0.4 -0.0 0.1 -0.0 0.0 -0.3 -0.7 0.4 -0.1 -0.2 -0.5 0.7
Irritable Bowel Disease (IBD) 0.4 0.9 2.5 0.6 1.5 0.9 -0.7 -0.4 0.7 0.6 0.4 -1.6 -1.3 0.2 -0.9 -1.1 -1.5 0.1
Ulcerative Colitis (UC) 0.6 1.2 4.0 0.2 0.7 -0.3 -0.9 -0.8 1.4 1.1 0.7 -2.0 -1.1 0.0 -1.2 -1.3 -1.8 -0.3
Major Depression (MDD) 0.1 0.1 0.5 -0.0 0.5 -0.4 -0.1 0.5 -0.7 0.4 0.4 -0.4 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3
Reaction Time 2.3 4.4 22.7 -0.2 -1.7 0.5 -1.1 -1.0 -4.8 -3.4 -4.2 1.4 0.5 0.6 -0.2 0.9 1.9 -1.5
Verbal and Numeric Reasoning (VNR) 1.0 2.5 6.2 2.1 1.9 1.6 1.1 1.6 1.5 0.5 1.3 0.0 1.5 2.4 1.9 1.0 0.6 2.5
Breast Cancer 0.9 2.1 5.4 1.5 -0.8 1.1 0.1 0.2 -0.2 -1.5 -1.3 1.7 2.1 2.0 1.5 1.9 2.3 1.0
Ovarian Cancer 0.4 0.5 1.2 -0.5 0.2 -0.2 1.0 -1.1 -0.1 0.0 -0.1 -0.7 -1.0 -0.8 -1.0 -0.9 -0.4 -1.1
Prostate Cancer 0.5 0.7 3.5 -0.5 -0.1 -0.5 1.9 0.9 -0.1 -0.9 -0.9 1.0 0.4 -0.4 0.3 0.4 1.6 -0.2
Age at First Birth 5.8 8.5 14.6 3.0 1.2 3.1 0.2 3.3 -0.6 -2.1 -0.4 3.5 3.7 3.7 3.8 3.8 3.3 3.5
Bipolar Disorder (2011) 2.4 2.3 5.3 -2.0 -2.0 -2.3 -0.5 -1.7 -0.1 1.6 1.1 -1.2 -0.8 -1.7 -1.5 -1.2 -1.2 -2.1
Body Mass Index (BMI) (2010) 0.9 1.3 4.6 -0.0 -1.7 0.7 -0.3 -0.1 -1.9 -1.7 -2.2 1.0 1.1 0.3 0.6 0.8 1.1 -0.4
Coronary Artery Disease (CAD) 1.1 1.3 4.5 -1.7 -1.5 0.0 0.6 -1.5 -1.3 -0.1 -0.8 -0.4 -0.7 -2.1 -0.8 -0.9 0.1 -1.7
Crohns Disease (2012) 0.5 0.8 3.7 0.8 1.9 1.7 -0.5 0.0 -0.2 0.5 0.6 -0.6 -0.9 0.4 -0.3 -0.5 -1.0 0.6
Mean Putamen Volume 0.3 0.3 3.0 0.2 -0.4 -0.4 -1.7 -0.4 -0.8 -0.0 0.0 -0.2 -0.1 0.0 -0.3 0.1 -0.7 -0.4
Fasting Glucose 1.1 1.4 6.7 0.1 0.6 -0.8 0.5 0.5 2.6 1.9 2.3 -1.0 -0.4 -0.4 -0.4 -0.7 -1.1 0.2
HbA1C 1.2 1.3 3.2 -1.2 0.5 -1.8 1.0 -0.2 1.6 1.5 1.0 -0.8 -1.3 -1.6 -0.8 -1.0 -1.1 -0.3
HDL Cholesterol 0.6 1.0 5.5 1.2 2.4 1.9 0.0 0.5 -0.2 -0.2 0.1 0.3 -0.1 1.0 0.8 0.5 -0.1 1.6
LDL Cholesterol 1.2 2.0 4.6 -1.3 -0.7 -2.1 0.8 -1.0 0.7 1.2 0.3 -1.6 -1.6 -1.8 -1.8 -1.8 -1.3 -1.6
Lupus 0.6 1.0 1.8 1.2 0.9 0.9 -1.3 0.7 -1.3 -1.0 -1.2 1.2 0.3 0.8 0.5 0.9 0.9 0.8
Neuroticism (2016) 0.6 0.9 4.1 1.2 1.6 2.0 -0.3 1.1 -0.2 -0.5 -0.4 0.3 -0.2 0.8 0.7 0.5 -0.2 1.4
Primary Biliary Cirrhosis 0.4 0.6 1.8 0.4 0.1 0.7 0.2 0.3 0.3 0.5 1.2 0.6 1.2 0.7 1.4 1.3 0.1 1.0
Rheumatoid Arthritis 0.2 0.3 0.9 -0.3 -0.5 -0.1 -0.9 -0.1 -0.9 0.1 0.2 0.9 0.8 0.2 0.7 0.7 0.6 0.4
Schizophrenia (2014) 1.2 2.7 10.2 -1.4 -3.0 -0.6 -1.6 -1.9 -3.2 -1.3 -1.9 0.5 0.1 -0.6 -0.8 0.3 0.2 -2.4
Triglycerides 0.5 0.9 2.2 -1.2 -0.7 -1.4 0.5 0.1 1.1 1.5 1.3 -1.0 -0.3 -1.0 -0.4 -0.9 -0.7 -0.6
Type 2 Diabetes (T2D) (2012) 0.8 0.9 1.9 1.1 0.8 1.0 0.1 1.0 0.4 -0.4 0.4 1.0 1.3 1.3 1.4 1.2 0.6 1.3
Ulcerative Colitis 0.6 0.9 2.6 0.5 0.0 0.6 -1.6 -1.2 -0.8 0.0 -0.8 -1.6 -1.0 0.5 -1.1 -1.0 -1.4 -0.6
Blood Eosinophil Count 4.7 36.3 82.4 5.6 1.1 3.7 -2.5 4.2 -4.8 -8.9 -7.6 9.1 5.6 6.0 4.8 7.5 8.6 3.5
Blood Platelet Count 0.5 5.9 19.5 4.4 3.2 2.7 -2.3 1.1 -0.5 -1.7 -1.4 2.2 1.4 3.8 1.6 2.4 1.3 2.8
Blood Red Count 0.1 1.4 6.5 1.5 -0.9 0.9 -0.6 0.3 -1.6 -0.7 -1.3 -1.1 1.4 2.5 0.9 0.0 0.2 1.1
Blood White Count 1.4 10.0 31.0 -0.5 0.2 -2.4 -1.1 -1.1 2.2 5.6 5.0 -5.5 -2.2 -0.7 -2.3 -3.6 -5.2 -0.7
Heel T-Score 0.5 4.2 17.1 -1.6 -4.1 -0.1 0.6 -1.1 -3.0 -2.9 -3.2 1.3 1.4 0.0 0.3 0.8 2.7 -1.7
BMI 0.6 3.6 16.9 0.8 0.4 1.7 -1.3 -1.2 -4.1 -3.2 -4.1 1.4 -0.6 0.5 -0.3 0.6 0.7 -0.5
Height 0.5 10.1 22.4 1.8 -0.0 1.2 4.0 3.9 0.0 -1.5 0.1 3.5 4.7 3.2 4.4 3.5 4.7 3.9
Waist Hip Ratio (WHR) 1.4 6.3 28.4 -0.4 0.5 -0.6 3.1 2.3 5.3 3.6 5.0 -0.8 1.7 0.1 2.0 0.2 -0.1 2.3
Systolic Blood Pressure 1.3 6.6 19.7 0.9 3.9 0.5 1.8 0.3 4.4 2.3 1.9 -2.7 -3.7 -1.6 -2.6 -2.6 -3.6 -0.5
Smoking Status 0.8 2.0 5.1 -1.5 -0.1 -1.1 2.2 0.8 2.2 1.8 1.9 -1.2 -0.8 -1.9 -0.3 -0.9 -1.6 -0.4
Allergy or Eczema 2.9 7.6 16.8 2.0 -0.2 3.0 -0.3 1.7 -1.8 -2.4 -1.5 3.0 4.1 3.5 4.0 3.7 3.2 3.0
Cardiovascular Disease 0.1 0.3 1.1 -0.0 0.5 0.7 0.4 0.0 0.0 -0.6 -0.9 0.0 -1.1 -0.7 -0.7 -0.4 -0.4 -0.5
Hypothyroidism (self reported) 1.8 4.0 11.3 -2.8 -1.5 -2.2 -0.9 -1.7 0.1 1.0 -0.0 -1.0 -2.6 -3.4 -2.6 -2.1 -1.7 -2.8
Respiratory disease 1.3 2.8 10.1 0.2 -1.9 0.6 0.2 0.1 -0.7 -1.2 -0.4 2.0 3.2 1.5 2.6 2.5 2.3 1.1
Type 2 Diabetes (T2D) (2018) 1.2 2.2 5.4 1.8 0.9 1.6 -0.4 0.8 -0.5 -0.6 -0.1 1.5 2.1 2.3 2.0 2.2 1.5 1.6
Lung FEV1/FVC ratio 0.6 3.2 10.9 -3.3 -2.2 -2.0 0.9 -0.3 0.8 1.2 0.7 -0.9 -1.4 -3.3 -1.5 -1.6 -0.7 -2.4
Lung FVC 1.5 7.9 20.7 1.3 -1.1 2.3 1.4 1.8 -2.7 -4.5 -3.9 3.7 2.9 2.2 2.7 3.2 4.0 1.4
Neuroticism 1.0 2.3 6.8 -1.7 0.1 -1.3 0.8 -0.0 1.7 2.6 2.6 -1.5 -1.1 -2.0 -0.5 -1.3 -1.8 -0.2
Chronotype (morning person) 0.6 1.5 4.3 -1.2 -0.7 0.4 0.2 -1.3 -1.4 -1.0 -2.1 -0.9 -1.6 -1.1 -1.3 -1.3 -0.8 -1.5
Hair Pigment 0.1 3.0 9.4 1.0 1.7 0.5 1.2 1.6 2.4 2.1 3.1 0.1 1.8 1.1 2.2 0.9 0.0 2.6
Tanning 0.2 2.8 6.0 -1.6 -0.5 -1.1 0.5 -1.9 0.4 1.3 0.6 -2.2 -2.2 -1.7 -2.3 -1.9 -2.2 -2.4
Hand grip strength (left) 1.5 4.0 7.7 1.6 -0.2 1.7 1.7 1.9 -0.7 -2.7 -2.5 2.7 2.0 1.9 1.9 2.3 2.8 1.4
Number of treatments/medications taken 0.6 1.0 2.8 -1.5 -1.7 -0.5 1.5 0.8 0.5 0.1 0.4 1.1 1.1 -1.1 1.1 0.6 1.0 0.2
Average weekly spirits intake 1.6 2.0 4.8 -1.4 -0.5 -1.3 1.1 -1.0 2.2 1.3 0.9 -1.4 -1.5 -2.0 -1.5 -1.6 -1.5 -1.4
Sensitivity / hurt feelings 0.4 0.6 2.6 -0.4 0.6 -1.2 1.0 1.6 1.0 0.9 0.9 -0.1 0.0 -0.4 0.5 0.0 -0.4 0.8
Frequency of depressed mood in last 2 weeks 0.1 0.2 0.7 -0.5 -0.6 -0.7 0.9 0.1 0.8 0.1 -0.1 -0.2 0.3 -0.3 0.3 -0.0 0.2 -0.0
Hearing difficulty/problems: Yes 1.9 2.9 7.2 1.5 1.1 2.4 0.8 1.5 0.5 -0.2 0.7 1.2 2.2 2.2 2.7 2.1 1.3 2.7
Relative age of first facial hair 0.5 1.1 5.0 -0.3 0.4 1.3 2.2 0.4 0.7 0.4 0.7 1.0 1.2 -0.1 1.7 1.1 0.6 1.3
Other serious medical condition/disability diagnosed by doctor 1.2 1.6 4.2 -1.8 -0.4 -1.2 1.9 0.8 1.9 1.2 0.6 -0.9 -1.2 -2.0 -0.6 -1.4 -1.0 -0.5
Ever used hormone-replacement therapy (HRT) 0.5 0.7 4.8 -0.8 -0.6 -0.2 2.2 -0.2 -0.2 -0.1 0.5 1.0 0.8 -0.4 0.9 0.7 0.9 0.3
Ever had hysterectomy (womb removed) 0.4 0.4 1.8 -0.0 -0.6 0.1 -1.4 -0.3 -1.1 -1.0 -0.9 0.7 0.3 0.1 0.0 0.5 0.4 -0.4
Systolic blood pressure, automated reading 0.9 2.7 11.1 1.4 3.3 0.4 0.1 -0.5 1.9 0.9 0.2 -1.8 -2.7 -0.3 -2.0 -1.7 -2.2 -0.3
Eye problems/disorders: Diabetes related eye disease 0.3 0.3 1.8 0.1 -0.1 -0.7 -0.6 0.0 0.6 0.8 1.3 -0.1 0.6 0.3 0.4 0.3 -0.2 0.3
Angina 0.3 0.4 0.7 -0.5 -0.8 0.6 0.8 -0.8 -0.7 -0.6 -0.8 -0.4 -0.4 -0.2 -0.4 -0.2 -0.1 -0.8
Medication for hormone replacement therapy 1.7 1.9 4.8 0.3 0.0 1.6 1.3 0.6 -0.7 -2.2 -1.4 2.1 1.3 0.7 1.5 1.7 2.2 0.7
Vitamin and mineral supplements 0.9 1.2 3.4 -0.5 -0.5 -0.6 -0.6 -1.8 0.9 0.5 0.0 -1.1 -1.3 -0.9 -1.7 -0.9 -1.4 -1.8
Supplements: Zinc 0.2 0.3 1.0 0.2 0.8 0.6 0.6 1.0 0.6 0.1 0.2 -0.6 -0.6 0.0 -0.2 -0.6 -0.2 0.3
Medication: Co-codamol 0.4 0.5 1.8 -0.2 -0.2 -0.3 1.3 0.8 0.6 0.3 1.1 0.2 0.9 0.4 0.9 0.5 0.5 0.8
Medication: Metformin 0.3 0.4 1.1 0.1 0.1 -0.6 -0.3 -0.8 -0.4 1.0 1.1 -1.0 -0.2 0.3 -0.5 -0.3 -1.0 -0.5
Diabetes (father) 0.3 0.4 1.1 0.0 -0.4 0.7 0.7 0.9 0.0 0.9 1.1 -0.4 0.7 0.6 0.8 0.0 -0.2 0.8
Diabetes (mother) 0.4 0.5 1.6 -0.4 -1.0 -1.1 1.3 -0.9 -0.7 -0.1 -0.3 0.1 -0.2 -0.2 -0.6 -0.2 -0.1 -1.0
Severe depression (siblings) 2.2 2.5 8.5 0.9 0.8 1.7 -0.6 0.4 -1.0 -2.6 -2.1 2.9 0.9 0.6 1.2 2.0 2.1 0.8
Pack years adult smoking proportion 1.6 2.5 5.5 -1.0 -1.5 -2.2 0.3 -2.2 0.4 0.9 0.6 -1.8 -1.6 -1.1 -2.3 -1.7 -1.5 -2.3
Impedance of leg (right) 1.0 4.8 24.3 -0.4 0.8 -1.1 1.0 1.2 4.2 4.2 4.9 -1.8 -0.1 -0.6 -0.1 -1.0 -1.6 0.9
Leg fat-free mass (left) 0.3 1.7 7.0 0.4 -0.0 0.9 0.3 0.5 -2.2 -2.4 -2.6 1.6 0.5 0.4 0.7 0.8 1.4 0.4
Trunk fat percentage 0.6 2.6 6.1 -0.9 1.0 -1.3 -0.5 -1.7 0.6 2.1 1.2 -2.0 -2.2 -1.6 -1.8 -2.0 -2.5 -1.0
Hand grip strength (right) 1.0 2.8 7.7 1.0 -0.4 0.4 1.6 1.6 -0.6 -2.3 -2.2 2.5 1.8 1.1 1.3 2.0 2.8 0.7
Townsend deprivation index at recruitment 0.3 0.4 2.0 0.4 0.7 -0.5 -1.4 0.2 0.5 0.2 -0.0 -0.8 -0.8 -0.2 -0.8 -0.8 -0.7 -0.1
Current tobacco smoking 1.7 2.8 8.0 -0.3 0.7 -0.9 2.4 1.3 2.8 2.5 2.8 -2.0 -0.7 -1.0 -0.3 -1.3 -1.8 0.4
Average weekly fortified wine intake 0.5 0.6 3.2 -0.1 0.5 0.4 -0.9 -0.1 0.9 1.5 1.8 -0.9 -0.2 -0.1 -0.2 -0.5 -0.7 0.3
Maternal smoking around birth 0.1 0.2 1.0 -0.1 0.4 -0.1 -0.0 -0.1 0.8 0.8 1.0 -0.3 -0.1 -0.4 -0.1 -0.2 -0.5 -0.1
Fed-up feelings 0.6 1.1 3.2 -1.5 -0.5 -1.1 -0.2 -1.1 -0.9 -0.1 -0.9 -0.2 -1.4 -1.8 -1.3 -0.9 -0.6 -1.6
Frequency of unenthusiasm / disinterest in last 2 weeks 1.7 2.3 6.1 -2.1 -1.7 -2.5 0.2 -2.2 -0.2 1.0 0.3 -1.3 -1.0 -1.8 -1.3 -1.4 -1.2 -1.9
Relative age voice broke 2.3 3.5 7.5 2.1 1.6 2.7 0.6 1.0 -1.7 -1.8 -1.4 1.8 1.9 2.2 2.3 2.1 1.6 2.2
Taking other prescription medications 0.8 1.3 3.2 -1.0 -1.3 0.0 1.6 1.2 0.1 0.4 1.1 1.2 1.8 -0.3 1.8 1.1 1.2 0.9
Age when periods started (menarche) 1.2 2.8 11.0 0.9 1.2 -0.5 0.9 -0.6 2.2 3.3 3.3 -2.2 -0.2 0.5 -0.0 -0.9 -2.2 1.2
Bilateral oophorectomy (both ovaries removed) 1.7 1.9 3.7 1.6 1.5 1.4 -0.4 1.1 1.0 -0.6 0.5 1.6 1.6 1.7 1.6 1.9 1.3 1.7
Heel bone mineral density (BMD) T-score, automated (left) 1.2 2.7 7.7 -0.8 -1.9 0.4 1.7 -0.4 -2.3 -2.6 -2.8 1.9 1.2 0.1 1.0 1.3 2.2 -0.5
Tinnitus: Yes, but not now, but have in the past 1.1 1.2 7.1 1.9 2.7 0.4 -0.8 0.6 -0.7 -1.1 -0.9 0.8 -0.7 1.1 -0.2 0.6 0.1 0.8
Qualifications: CSEs or equivalent 1.1 1.4 4.1 -2.0 -1.9 -1.8 0.2 -0.6 -0.7 0.2 -0.2 -0.2 -0.6 -1.8 -1.1 -0.6 -0.4 -2.0
Serious illness, injury or assault to yourself 5.9 7.2 14.0 -2.6 -0.3 -2.0 -0.1 -1.5 1.7 3.1 2.1 -3.7 -3.3 -3.4 -3.0 -3.6 -3.7 -2.4
High blood pressure 0.3 0.9 4.1 0.2 2.0 0.3 0.2 0.2 0.9 0.6 0.4 -0.9 -1.8 -0.6 -1.0 -1.0 -1.4 -0.1
Hayfever, allergic rhinitis or eczema 2.8 6.0 11.4 2.3 0.9 2.5 -0.5 2.5 -1.0 -1.8 -1.1 2.5 3.2 3.3 3.4 3.0 2.9 3.0
Multivitamins +/- minerals 0.2 0.3 1.0 -0.1 0.2 -0.2 0.1 1.0 0.0 0.3 0.9 0.6 0.7 -0.0 0.8 0.4 0.6 0.8
Stomach or abdominal pain in last month 0.3 0.4 1.4 -0.1 -0.5 -0.4 0.9 -0.7 1.2 0.7 0.8 0.1 0.7 0.2 0.3 0.5 0.2 -0.1
Supplements: Glucosamine 0.6 0.8 2.1 -0.4 -0.7 0.5 0.9 0.2 -0.9 -1.0 -0.6 1.0 1.3 0.4 1.4 1.0 1.1 0.7
Diverticular disease/diverticulitis (self-reported) 0.4 0.5 4.6 -0.1 -0.4 -2.2 -0.3 -0.6 -0.0 0.5 0.3 -0.4 -0.2 -0.2 -0.8 -0.2 -0.4 -0.8
Medication: Atenolol 0.3 0.3 1.4 -0.2 -0.5 -1.0 0.8 1.0 1.2 0.4 0.4 -0.2 0.4 0.2 0.1 0.0 0.3 -0.0
Medication: Levothyroxine sodium 1.5 2.6 6.6 -2.3 -1.0 -1.9 -0.5 -0.7 1.2 2.0 1.6 -1.2 -1.3 -2.6 -1.4 -1.5 -1.6 -1.7
Sitting height 0.4 2.9 7.2 1.2 -0.2 0.5 2.0 2.1 -1.0 -2.2 -2.2 2.1 1.6 1.5 1.5 1.3 2.7 1.5
Chronic bronchitis/emphysema (father) 0.8 0.9 3.5 -1.4 -1.3 -1.1 1.1 0.2 0.4 1.1 1.9 0.3 0.9 -1.0 0.8 0.4 0.3 0.2
High blood pressure (mother) 0.3 0.5 1.8 0.1 0.6 0.1 0.4 0.4 1.2 1.2 1.3 -0.7 -0.4 -0.1 -0.3 -0.5 -0.7 0.1
Body mass index (BMI) 0.4 1.8 7.3 -0.6 -0.2 0.5 -0.1 -1.8 -2.7 -1.8 -2.7 0.3 -1.2 -0.8 -0.9 -0.4 -0.2 -1.3
Impedance of leg (left) 1.1 5.1 24.1 -0.6 0.3 -1.7 0.8 0.1 4.0 4.5 4.9 -2.4 -0.3 -0.7 -0.5 -1.3 -2.0 0.3
Leg predicted mass (left) 0.3 1.7 6.9 0.4 -0.1 0.9 0.4 0.5 -2.3 -2.4 -2.6 1.6 0.5 0.4 0.7 0.9 1.4 0.4
Trunk fat mass 0.2 0.8 1.9 -0.5 0.6 -0.8 -0.1 -1.1 -0.2 1.0 0.2 -1.1 -1.3 -0.9 -1.0 -1.2 -1.4 -0.4
Waist circumference 0.1 0.5 2.8 -0.9 -0.1 -0.4 1.7 -0.3 0.2 0.8 0.5 -0.5 -0.5 -0.9 -0.1 -0.7 -0.7 -0.0
Number of incorrect matches in round 0.3 0.6 2.3 0.8 1.1 0.4 -1.5 0.3 -1.1 -0.9 -1.0 0.7 -0.1 0.2 0.0 0.3 0.5 0.4
Past tobacco smoking 1.1 1.9 7.3 2.1 0.3 0.9 -0.3 0.7 -0.5 -1.1 -0.5 1.0 2.0 2.7 1.5 1.5 1.6 1.5
Alcohol usually taken with meals 0.7 1.2 4.6 -0.9 -2.0 -0.6 -0.5 -0.7 -0.7 -1.4 -2.1 -0.2 -0.2 -0.3 -1.0 -0.6 0.8 -1.7
Nervous feelings 1.0 1.8 4.6 -1.1 0.9 0.1 -1.2 -1.0 1.6 1.8 1.7 -0.7 -1.7 -2.2 -1.1 -1.0 -2.0 -0.8
Frequency of tenseness / restlessness in last 2 weeks 1.3 2.1 5.1 -2.2 -2.0 -2.1 1.8 -0.9 0.5 1.6 1.3 -1.4 -0.5 -1.7 -0.8 -1.3 -0.7 -1.4
Hearing difficulty/problems with background noise 1.0 1.7 4.8 1.0 1.5 1.9 1.1 1.2 0.2 -0.4 0.3 1.0 1.2 1.2 1.9 1.2 1.1 2.2
Hair/balding pattern: Pattern 2 0.8 1.0 5.7 -1.2 -0.4 -0.1 1.4 0.8 0.8 1.8 2.4 -0.5 0.3 -0.9 0.5 -0.2 -0.4 0.2
Had menopause 0.4 0.5 3.0 -0.3 -0.3 -0.5 0.2 -1.7 -1.0 -0.4 -0.9 -0.2 -0.7 -0.3 -0.8 -0.5 0.1 -0.9
Had other major operations 3.8 4.7 12.3 -2.9 -3.3 -3.1 -0.4 -2.8 -2.5 -0.5 -1.1 -0.6 -1.2 -2.2 -2.2 -1.4 -0.6 -3.5
Forced vital capacity (FVC) 2.0 7.7 19.3 0.4 -2.5 1.0 2.6 1.8 -2.4 -3.3 -2.5 3.8 3.8 1.9 3.2 3.3 4.4 1.5
Heel bone mineral density (BMD) T-score, automated (right) 0.6 1.4 4.1 -1.4 -2.0 -0.4 1.3 0.0 -1.6 -1.4 -1.6 1.1 0.8 -0.7 0.6 0.6 1.4 -0.7
Ever unenthusiastic/disinterested for a whole week 2.1 2.6 5.7 -1.9 -0.9 -1.8 -0.4 -1.8 0.5 1.2 0.4 -1.4 -2.0 -2.1 -2.1 -1.6 -2.0 -2.4
Qualifications: None of the above 0.7 1.4 4.4 -1.7 -1.0 -1.4 1.9 -1.4 1.1 0.6 0.2 -0.3 -0.7 -2.1 -0.7 -0.8 -0.7 -1.1
Financial difficulties in last 2 years 0.5 0.6 2.1 0.3 -1.4 0.0 -0.4 0.4 -1.2 -1.2 -1.1 0.1 0.7 1.0 0.5 0.0 1.0 0.5
Mouth/teeth dental problems 1.0 1.5 4.5 2.1 0.8 2.0 -1.4 1.7 0.4 -0.1 0.1 -0.1 0.9 1.9 0.8 0.5 0.5 1.4
Heart attack 0.5 0.7 2.4 0.4 -0.4 0.8 0.8 0.2 -1.5 -0.9 -1.1 0.6 0.8 0.9 0.9 0.7 0.4 0.7
Allergy 1.6 3.7 9.7 -1.5 -0.3 -1.2 0.4 -1.9 0.6 0.8 0.1 -2.0 -3.1 -2.4 -3.0 -2.7 -2.3 -2.5
Pain all over the body in last month 1.0 1.0 5.8 -0.4 0.9 -0.7 0.8 -0.1 2.4 1.6 2.0 -0.2 -0.0 -0.7 0.3 0.0 -0.5 0.5
Diabetes (self-reported) 0.5 0.7 3.0 -0.4 0.2 -1.1 -0.0 -0.6 1.0 1.6 1.7 -0.9 -0.2 -0.4 -0.5 -0.4 -0.9 -0.6
Hayfever/allergic rhinitis (self-reported) 0.6 0.8 4.8 0.4 0.6 2.2 0.2 0.9 -0.5 -0.9 -0.8 0.7 0.5 0.3 1.2 0.5 0.8 1.0
Medication: Ramipril 0.4 0.5 2.5 -1.6 -1.5 -0.9 0.1 0.3 -0.3 0.4 0.4 0.1 0.0 -1.0 -0.1 -0.3 -0.2 -0.6
Medication: Simvastatin 0.3 0.4 2.6 0.0 -0.0 0.1 1.6 1.2 0.3 -0.1 -0.6 0.6 0.6 0.0 0.7 0.5 0.3 0.5
Fluid intelligence score 0.3 0.5 2.2 0.6 0.6 0.3 1.5 0.5 1.0 0.6 0.9 -0.3 0.7 0.8 0.7 0.3 0.2 0.8
Illnesses of siblings 1.0 1.4 8.9 -1.4 -1.1 -3.0 -1.3 0.4 0.1 1.0 0.9 -0.5 -0.5 -1.5 -1.0 -0.7 -0.5 -1.2
Neuroticism score 0.3 0.7 2.0 -0.9 0.5 -0.5 0.3 -0.1 0.2 0.9 0.5 -0.9 -1.3 -1.4 -0.7 -1.0 -1.3 -0.3
Weight 0.2 1.1 5.2 -0.0 -0.3 0.5 0.8 -0.4 -2.2 -1.8 -2.3 1.0 0.1 0.1 0.2 0.3 0.9 -0.0
Impedance of arm (right) 1.4 6.7 23.3 -0.0 1.7 -2.4 -1.8 0.4 4.3 4.6 4.8 -2.9 -1.3 -0.9 -1.3 -1.9 -3.1 0.2
Arm fat percentage (right) 0.4 1.5 3.9 -0.5 0.7 -0.7 -1.1 -1.8 -1.2 0.2 -0.7 -0.9 -2.0 -1.2 -1.7 -1.3 -1.6 -1.4
Trunk fat-free mass 0.9 5.4 14.4 0.8 -1.3 1.7 1.8 1.4 -3.1 -3.8 -3.6 2.7 2.1 1.6 2.0 1.9 3.3 1.2
Hip circumference 0.3 1.2 4.6 -1.0 -0.8 -0.4 0.0 -1.4 -2.1 -0.5 -1.3 -0.5 -1.3 -0.9 -1.2 -1.0 -0.8 -1.2
Time employed in main current job 0.4 0.4 4.0 -0.4 0.1 0.0 2.0 0.5 0.0 0.2 0.5 0.7 0.4 -0.3 0.7 0.5 0.4 0.5
Alcohol intake versus 10 years previously 1.5 2.3 9.6 -2.3 -3.1 -2.8 -0.3 -1.0 -2.0 -0.4 -0.4 0.9 0.6 -1.4 -0.3 0.2 0.8 -1.8
Father’s age at death 2.1 2.8 9.2 0.5 0.5 -1.0 -1.1 -1.8 1.1 2.1 1.6 -3.0 -1.8 0.1 -2.2 -2.2 -2.3 -0.8
Worrier / anxious feelings 0.5 1.0 3.6 -0.9 0.4 -0.0 -0.9 -0.9 -0.3 0.3 -0.3 -0.7 -1.9 -1.5 -1.4 -1.2 -1.3 -1.2
Frequency of tiredness / lethargy in last 2 weeks 0.3 0.5 0.9 -0.5 0.6 -0.3 0.0 -0.7 0.9 0.9 0.8 -0.6 -0.9 -0.9 -0.5 -0.7 -0.9 -0.3
Falls in the last year 1.4 2.0 4.7 -1.3 -1.2 -1.1 -0.3 -2.2 -0.7 0.9 0.0 -1.9 -1.4 -1.2 -1.7 -1.6 -1.6 -1.9
Hair/balding pattern: Pattern 3 1.6 2.4 5.7 0.2 2.3 -0.6 -1.1 -0.8 1.5 1.8 1.3 -1.7 -2.4 -1.0 -1.7 -1.6 -2.4 -0.6
Number of live births 2.5 3.5 9.9 -3.0 -3.2 -1.9 1.3 -1.9 -0.5 0.1 -0.6 -1.3 -1.2 -2.5 -1.8 -1.9 -0.6 -2.8
Forced expiratory volume in 1-second (FEV1) 1.5 5.1 13.2 -1.0 -3.3 0.1 2.6 1.3 -2.0 -2.6 -2.1 3.2 2.8 0.3 2.1 2.4 3.6 0.1
Pulse rate 0.2 0.3 2.3 -0.9 -0.6 -0.1 1.5 -0.3 0.5 0.1 -0.2 -0.0 -0.2 -0.8 -0.1 -0.2 -0.1 -0.6
Happiness 0.8 1.0 3.4 -0.8 -0.5 0.3 -1.8 -0.8 -1.6 -0.4 -0.9 -0.7 -1.1 -0.5 -1.1 -1.0 -0.5 -1.2
Noisy workplace 0.8 1.0 2.5 -1.5 -1.3 -1.1 0.7 0.8 0.1 -1.0 -0.8 1.4 0.2 -1.6 -0.1 0.5 1.0 -1.2
Qualifications: A levels/AS levels or equivalent 0.6 1.4 3.8 0.0 0.4 -0.8 -0.8 -0.6 1.9 1.7 1.7 -1.6 -1.0 -0.3 -1.1 -1.2 -1.5 -0.6
Serious illness, injury or assault of a close relative in last 2 years 0.9 1.1 3.2 -0.5 0.9 -0.4 -0.2 -0.6 1.3 1.6 1.8 -1.3 -1.1 -0.8 -0.8 -1.2 -1.2 -0.2
Mouth/teeth dental problems: Dentures 1.4 2.4 7.2 -2.7 -1.2 -2.6 1.7 -1.2 -0.2 1.2 0.9 -0.4 -1.0 -2.6 -1.0 -1.0 -1.1 -1.8
Asthma 2.3 4.6 11.8 1.8 -0.2 1.4 0.2 0.6 -1.3 -1.7 -0.9 2.7 3.4 2.6 3.0 3.1 2.9 2.1
Medication: Ibuprofen (e.g. Nurofen) 0.7 0.8 2.1 -0.2 -1.2 -0.7 -1.4 -1.1 -0.8 -0.7 -0.9 -0.4 -0.8 -0.6 -1.3 -0.7 -0.2 -1.4
Medication: Cholesterol lowering 0.4 0.7 3.3 -0.1 -0.4 0.4 0.1 -0.1 -1.7 -1.3 -1.8 0.8 0.3 0.3 0.3 0.4 0.8 -0.1
Depression (self-reported) 0.6 0.8 5.6 -0.3 0.2 0.1 2.4 -0.0 2.0 0.8 0.7 -0.1 0.2 -0.4 0.4 0.2 -0.3 0.1
Medication: Lansoprazole 0.4 0.5 1.8 -0.2 0.3 -0.7 1.3 -0.0 0.8 1.3 1.1 -0.3 0.4 -0.1 0.5 0.2 -0.6 0.5
Prospective memory result 0.3 0.3 1.2 0.7 0.7 0.9 0.2 0.3 1.1 0.1 0.1 -0.7 -0.5 0.2 -0.2 -0.5 -0.5 0.5
Lung cancer (father) 1.5 1.8 3.7 -1.6 -0.6 -1.3 0.6 -0.6 1.2 1.6 1.7 -1.5 -1.2 -1.9 -1.2 -1.5 -1.5 -1.1
Illnesses of mother 0.4 0.5 1.7 -0.3 -0.9 -1.2 -0.5 0.5 -0.9 -0.9 -1.3 0.5 0.5 -0.1 0.1 0.2 1.1 -0.4
Forced expiratory volume in 1-second (FEV1), Best measure 0.8 2.4 7.8 -1.5 -2.8 -1.2 2.1 1.0 -1.0 -1.4 -1.1 2.1 1.5 -0.8 0.9 1.2 2.2 -0.7
Pulse wave Arterial Stiffness index 0.6 0.7 2.4 0.5 0.8 0.8 0.2 1.2 0.7 0.2 0.9 0.7 1.0 0.4 1.4 0.8 0.3 1.5
Impedance of arm (left) 1.9 8.8 30.8 -0.2 1.9 -2.6 -1.8 0.2 5.0 5.3 5.5 -3.1 -1.6 -1.3 -1.6 -2.1 -3.4 0.1
Arm fat mass (right) 0.2 0.7 3.7 -0.0 0.3 0.1 -0.2 -1.1 -1.9 -1.0 -1.7 0.1 -0.9 -0.4 -0.7 -0.4 -0.3 -0.6
Trunk predicted mass 1.0 5.6 14.9 0.8 -1.3 1.7 1.8 1.5 -3.1 -3.9 -3.7 2.8 2.2 1.6 2.0 1.9 3.4 1.2
Standing height 0.4 3.7 10.4 1.1 -0.2 0.2 2.4 3.2 0.8 -0.2 0.6 1.5 2.8 1.9 2.6 1.6 2.5 2.8
Length of working week for main job 0.4 0.5 3.4 -0.2 -0.7 -0.0 -1.9 -0.4 -1.4 -0.5 -0.6 -0.1 -0.1 0.1 -0.3 0.0 -0.4 -0.7
Exposure to tobacco smoke at home 3.0 3.3 7.4 -2.4 -1.8 -2.4 -0.1 -2.3 0.4 1.5 1.0 -1.1 -1.6 -2.7 -2.1 -1.7 -1.3 -2.6
Breastfed as a baby 3.3 4.1 7.1 2.0 1.6 1.9 -0.1 2.3 -1.0 -1.7 -0.9 2.6 2.1 2.0 2.6 2.6 2.2 2.7
Tense / ‘highly strung’ 0.5 0.9 2.3 -0.9 1.2 -0.3 0.3 0.1 0.8 1.2 0.8 -0.8 -1.4 -1.5 -0.8 -1.1 -1.1 -0.2
Seen doctor (GP) for nerves, anxiety, tension or depression 0.3 0.4 1.1 -0.9 0.2 -1.0 0.8 0.9 1.0 0.6 0.5 0.1 -0.4 -1.0 0.2 -0.1 -0.4 0.2
Hair/balding pattern: Pattern 4 0.2 0.5 1.2 0.5 1.0 0.7 0.7 0.6 -0.2 -0.5 -0.5 1.1 0.3 -0.3 0.9 0.7 0.2 1.0
Birth weight of first child 1.4 2.5 7.8 -0.7 -1.2 0.7 0.6 0.5 -1.0 -2.1 -2.0 2.8 1.8 0.0 1.6 2.1 2.6 0.1
Peak expiratory flow (PEF) 2.0 4.6 10.9 -0.9 -3.2 -0.3 3.0 0.5 -1.8 -2.2 -2.0 2.9 2.8 0.5 2.0 2.4 3.3 -0.2
Pulse wave reflection index 0.3 0.3 2.1 0.3 0.4 0.4 -0.2 0.4 -0.2 0.4 1.4 0.1 0.5 0.4 0.8 0.3 0.0 1.0
Ever highly irritable/argumentative for 2 days 0.5 0.6 1.9 -1.1 -0.6 -0.7 1.2 1.4 -0.1 0.2 0.4 0.9 0.7 -0.9 1.0 0.6 0.6 0.1
Loud music exposure frequency 0.2 0.2 1.1 -0.3 -0.8 -0.5 0.0 0.3 -1.1 -0.5 -0.4 -0.1 -0.1 -0.3 -0.3 -0.2 0.1 -0.6
Qualifications: O levels/GCSEs or equivalent 1.3 2.1 5.1 -0.7 0.1 -1.3 -1.3 -1.1 1.3 2.2 2.3 -1.9 -1.2 -0.9 -1.4 -1.4 -2.1 -1.0
Mouth/teeth dental problems: Bleeding gums 1.2 1.5 6.8 0.5 0.5 0.4 -1.2 -1.4 -1.8 -1.8 -2.6 -0.2 -1.4 0.4 -1.4 -0.6 -0.1 -1.0
Blood clot in the leg (DVT) 1.6 2.1 4.2 1.3 -0.2 0.8 -0.5 1.4 -2.0 -2.0 -1.7 1.9 1.4 1.5 1.2 1.5 1.9 1.0
Medication: Paracetamol 0.5 0.8 3.3 -1.7 -1.8 -0.7 -0.1 -1.1 -0.3 -0.5 -0.1 0.5 0.4 -1.1 -0.0 0.4 0.3 -1.4
Headache pain in last month 2.0 3.5 11.3 -2.4 -3.0 -2.0 0.2 -3.0 -0.6 0.1 -0.8 -1.1 -1.0 -1.8 -2.1 -1.2 -1.1 -3.4
Medication for cholesterol, blood pressure or diabetes 0.3 0.5 1.8 0.5 -0.8 0.0 -0.4 -0.5 -0.6 -0.2 0.4 0.6 1.3 0.9 0.8 1.0 0.8 0.2
Glaucoma (self-reported) 0.8 0.9 3.9 -0.1 1.2 0.1 0.2 0.8 1.9 1.4 2.0 -1.0 -0.4 -0.4 0.0 -0.5 -1.0 0.4
Gout (self-reported) 0.7 1.0 2.9 -0.5 -1.2 -0.6 0.9 1.0 1.1 1.0 1.7 -0.0 1.6 0.4 1.2 0.5 0.7 0.8
Hypothyroidism/myxoedema (self-reported) 1.9 3.6 12.6 -3.3 -2.1 -2.4 0.3 -0.7 0.6 1.3 0.6 -0.8 -1.8 -3.5 -1.9 -1.8 -1.2 -2.4
Medication: Amlodipine 1.5 2.2 5.9 -2.3 -1.1 -1.9 1.1 0.2 2.1 1.6 1.4 -0.8 -0.9 -2.4 -0.9 -1.1 -1.0 -1.4
Medication: Ventolin 100micrograms inhaler 0.7 0.9 3.0 -0.3 -1.0 -0.6 -0.2 -0.4 -1.0 0.5 1.1 1.1 1.7 0.3 1.4 1.5 0.5 0.5
Birth weight 4.4 9.6 17.7 3.1 0.1 3.1 -1.8 1.6 -2.6 -3.4 -3.0 3.3 3.7 4.2 3.4 3.6 3.9 2.9
Chronic bronchitis/emphysema (mother) 0.2 0.2 0.7 -0.1 0.6 0.4 -0.7 0.0 0.2 0.2 0.4 -0.3 -0.8 -0.6 -0.4 -0.5 -0.8 0.2
High blood pressure (siblings) 1.8 2.6 9.3 2.3 1.5 3.1 0.2 0.4 -0.9 -1.8 -1.5 1.4 0.9 2.3 1.4 1.4 1.2 1.8
Forced vital capacity (FVC), Best measure 1.2 4.3 11.0 0.1 -2.2 -0.1 2.1 1.6 -1.6 -2.3 -1.6 3.2 2.9 1.0 2.3 2.5 3.3 0.9
Body fat percentage 0.5 1.8 4.2 -0.8 0.6 -1.0 -0.5 -1.8 -0.1 1.4 0.5 -1.6 -2.0 -1.4 -1.7 -1.6 -2.1 -1.1
Leg fat percentage (right) 0.2 0.7 1.7 -0.6 0.5 -0.2 0.2 -1.2 -0.7 0.5 -0.1 -0.8 -1.3 -0.9 -1.0 -0.9 -1.2 -0.8
Arm fat-free mass (right) 0.7 3.4 8.8 0.0 -1.3 1.1 2.0 0.8 -2.4 -3.0 -3.0 2.2 1.6 0.7 1.5 1.4 2.7 0.6
Exposure to tobacco smoke outside home 1.7 2.3 4.9 -1.2 -1.6 -2.2 -1.4 -2.0 -1.3 0.4 -0.5 -1.2 -1.3 -1.2 -2.0 -1.4 -1.3 -2.2
Comparative body size at age 10 0.8 2.3 9.2 -1.3 -1.9 -0.0 0.1 -3.0 -0.7 -1.0 -2.0 -1.2 -1.4 -1.1 -1.7 -1.4 -0.7 -2.3
Number of full brothers 3.9 4.9 11.6 -3.4 -2.2 -3.1 1.1 -2.2 0.6 1.5 0.7 -1.3 -1.8 -3.3 -2.2 -1.7 -1.8 -3.2
Worry too long after embarrassment 0.4 0.7 5.6 0.4 2.4 0.5 -0.5 1.3 0.3 0.1 -0.0 -0.0 -1.3 -0.4 -0.3 -0.5 -0.6 0.7
Seen a psychiatrist for nerves, anxiety, tension or depression 0.6 0.8 2.8 -0.6 1.0 -1.2 0.9 -0.3 1.7 1.2 1.1 -0.3 -0.7 -0.8 -0.2 -0.2 -0.9 0.1
Wheeze or whistling in the chest in last year 0.5 1.0 4.2 -0.7 -1.6 -1.4 -0.3 -2.1 -1.9 0.2 -0.3 -0.7 0.2 -0.1 -0.4 -0.3 -0.4 -0.9
Number of children fathered 0.7 0.8 4.3 -1.5 -2.1 -1.5 0.6 -0.0 0.3 0.5 0.5 -0.6 0.4 -1.0 -0.1 -0.6 0.3 -0.5
Reason for reducing amount of alcohol drunk: Health precaution 0.2 0.2 1.3 0.3 1.1 0.2 -0.1 -0.0 0.3 -0.2 -0.1 -0.3 -0.8 -0.2 -0.6 -0.2 -0.7 -0.3
Age at first live birth 0.8 1.4 3.9 2.0 1.2 1.4 -0.5 1.1 0.2 -0.9 -0.8 1.0 0.7 1.8 1.1 1.0 0.8 1.7
Pulse wave peak to peak time 0.7 0.9 2.5 -0.5 -0.8 -0.9 -0.3 -1.2 -0.9 -0.3 -1.1 -0.7 -1.0 -0.5 -1.5 -0.9 -0.3 -1.6
Health satisfaction 2.1 2.8 6.2 -2.3 -1.4 -1.6 -1.1 -1.4 0.2 0.4 -0.5 -1.4 -2.0 -2.5 -2.1 -2.0 -1.3 -2.4
Shortness of breath walking on level ground 0.9 1.0 2.8 -0.1 0.9 0.1 -0.9 -0.4 1.7 0.7 0.5 -1.0 -1.6 -1.0 -1.4 -1.1 -1.4 -0.8
Qualifications: College or University degree 0.3 0.9 8.6 0.6 0.3 0.7 -2.9 -0.4 -0.1 -0.6 -0.9 -0.3 -0.8 0.4 -1.0 -0.6 -0.1 -0.5
Eye problems/disorders: None of the above 0.6 0.7 2.5 0.3 -0.0 0.5 -1.4 -0.2 -1.6 -1.2 -1.6 0.5 -0.4 0.2 -0.6 -0.0 0.6 -0.6
Mouth/teeth dental problems: Loose teeth 4.8 5.7 14.4 -3.4 -1.6 -3.8 1.5 -1.3 0.8 1.9 1.2 -1.8 -2.2 -3.7 -2.5 -2.4 -1.8 -3.1
Emphysema/chronic bronchitis 3.0 3.3 6.3 -2.3 -1.5 -1.3 0.8 -1.8 1.0 2.5 2.2 -2.2 -1.3 -2.2 -1.3 -1.8 -2.4 -1.5
Medication for pain relief, constipation, heartburn 0.8 1.4 4.7 1.6 2.2 -0.2 -0.5 0.6 1.2 1.8 1.9 -1.0 0.0 1.2 0.3 -0.2 -0.9 1.6
Neck or shoulder pain in last month 0.7 0.9 4.2 -0.6 -0.6 -1.0 -0.9 -2.0 -0.8 -0.2 -0.7 -0.7 -1.0 -0.6 -1.2 -1.0 -0.5 -1.1
Medication: Blood pressure 1.1 2.0 5.6 -0.9 0.9 -0.2 0.5 -0.1 1.7 1.4 0.7 -1.8 -2.4 -1.6 -1.6 -2.2 -2.0 -0.7
Angina (self-reported) 0.2 0.3 0.6 -0.4 -0.5 0.4 0.7 -0.7 -0.7 -0.4 -0.6 -0.3 -0.5 -0.3 -0.4 -0.2 -0.2 -0.7
Migraine (self-reported) 0.8 0.9 2.4 -1.5 -1.3 -1.4 1.0 0.3 1.2 0.8 1.2 0.4 0.9 -1.1 0.4 0.6 0.4 -0.7
Medication: Ibuprofen 0.3 0.3 1.3 0.3 -0.9 -0.4 -1.2 -0.3 -0.4 -0.8 -0.8 -0.1 -0.2 -0.0 -0.6 -0.3 0.2 -0.6
Medication: Allopurinol 0.8 1.0 3.2 -0.9 -0.6 -1.2 1.8 1.0 1.5 1.4 1.6 -0.7 0.5 -0.4 0.3 -0.3 -0.4 0.1
Medication: Omeprazole 0.6 0.7 2.2 -0.2 -0.0 1.3 0.6 0.0 -0.4 -0.3 0.2 1.4 1.2 0.0 1.5 1.3 0.9 0.8
Medication: Seretide 50 evohaler 0.8 0.9 3.0 0.1 -0.5 1.0 1.4 0.1 0.0 -0.0 0.0 0.6 1.6 1.0 1.7 1.2 0.5 1.1
Mean time to correctly identify matches 2.4 4.6 21.0 0.1 -1.4 1.1 -1.2 -1.3 -4.6 -3.6 -4.5 1.4 0.4 1.0 -0.2 0.8 2.0 -1.3
Heart disease (mother) 0.8 1.0 3.0 0.3 1.3 0.9 1.5 -1.7 -0.2 -0.7 -1.4 -0.5 -1.4 -0.1 -0.9 -0.5 -0.9 -0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.8 1.0 2.1 -0.7 -0.3 -1.2 -0.9 -1.0 0.6 0.9 0.6 -1.2 -1.2 -0.8 -1.4 -1.3 -0.9 -1.0
Whole body fat mass 0.1 0.6 1.5 -0.5 0.5 -0.3 0.2 -1.2 -1.1 0.3 -0.4 -0.7 -1.2 -0.8 -0.8 -0.9 -1.1 -0.5
Leg fat mass (right) 0.1 0.5 2.0 -0.4 0.3 -0.1 0.5 -1.0 -1.4 -0.3 -0.9 -0.2 -1.0 -0.6 -0.7 -0.5 -0.7 -0.6
Arm predicted mass (right) 0.6 2.9 6.8 0.0 -1.3 1.1 2.0 0.7 -2.1 -2.6 -2.6 2.1 1.6 0.7 1.5 1.3 2.5 0.7
Pulse rate, automated reading 0.5 1.6 6.2 -1.2 -0.2 -0.4 2.0 0.3 1.8 2.2 2.5 -0.6 0.3 -1.1 0.7 -0.3 -1.0 0.4
Alcohol intake frequency. 0.6 1.3 3.4 -1.2 -1.4 -1.2 0.7 -1.3 -1.6 -1.1 -1.5 0.3 -0.6 -1.2 -0.9 -0.2 0.0 -1.9
Comparative height size at age 10 0.6 3.1 8.9 1.1 0.6 0.9 1.6 3.0 0.9 -0.8 -0.2 1.7 2.2 1.7 2.3 1.5 2.7 2.5
Number of full sisters 0.6 0.8 4.4 -0.8 -2.1 -0.2 -0.4 -1.3 -1.1 -0.4 -0.3 -0.2 0.1 -0.5 -0.6 -0.1 0.1 -1.5
Suffer from ‘nerves’ 1.2 1.9 8.1 -0.4 1.7 -1.2 0.4 0.2 2.8 2.1 2.1 -0.9 -1.1 -1.3 -0.4 -0.7 -1.7 0.4
Overall health rating 0.2 0.4 1.5 -1.2 -1.1 -0.5 0.6 0.4 0.3 0.2 0.3 0.2 0.1 -1.2 0.3 -0.1 0.0 -0.2
Chest pain or discomfort 2.2 3.1 8.6 -2.9 -1.8 -2.3 0.9 -2.4 -0.2 1.2 0.5 -1.1 -1.2 -2.8 -1.5 -1.5 -1.1 -2.4
Had major operations 1.8 2.1 7.3 -0.4 -0.5 -0.4 2.0 2.7 1.7 0.4 1.1 1.0 1.9 0.2 2.0 0.9 1.7 1.7
Age at last live birth 0.1 0.1 0.4 -0.0 -0.6 -0.4 0.6 -0.1 -0.1 -0.1 -0.3 0.0 -0.1 -0.0 -0.2 -0.3 0.0 -0.2
Family relationship satisfaction 0.1 0.1 0.4 -0.4 -0.1 0.4 -0.0 0.6 0.6 -0.1 0.3 0.1 0.2 -0.2 0.4 -0.1 0.5 0.3
Leg pain on walking 0.6 0.7 2.2 -0.9 -0.8 -1.5 0.5 -1.1 0.9 1.1 0.9 -0.8 -0.1 -0.5 -0.5 -0.6 -0.7 -0.8
Qualifications: NVQ or HND or HNC or equivalent 0.4 0.4 2.2 -0.6 -0.8 -0.9 0.3 -1.1 -1.5 0.5 0.5 -0.0 0.2 -0.1 -0.1 0.3 -0.4 -0.7
Commuting to job workplace: Car/motor vehicle 0.3 0.4 1.5 -1.1 -1.2 -0.8 -0.0 -0.8 -0.6 0.1 0.2 -0.1 -0.1 -0.7 -0.4 -0.4 0.2 -0.8
Illness, injury, bereavement, stress in last 2 years 1.2 1.5 3.6 0.6 -0.7 1.3 -0.9 -0.2 -1.9 -1.4 -1.0 1.5 1.6 1.4 1.1 1.8 1.3 0.2
Medication: Aspirin 0.1 0.2 1.1 -0.1 -0.3 0.5 0.6 0.5 -0.4 -0.5 -1.0 -0.2 -0.2 0.1 -0.2 -0.1 0.1 -0.5
Supplements: Vitamin C 0.9 1.0 3.8 -0.2 -1.9 -0.8 1.4 -0.1 -1.5 -1.2 -1.7 -0.0 0.7 0.6 0.0 -0.3 1.3 -0.3
Knee pain experienced in last month 0.3 0.5 2.0 -0.5 0.1 -0.5 1.2 -0.1 0.7 1.1 1.4 -0.6 -0.2 -0.6 -0.1 -0.6 -0.6 0.2
Hypertension (Self-reported) 0.4 1.2 3.6 -0.3 1.6 -0.4 -0.2 -0.0 1.3 1.0 0.8 -1.1 -1.9 -1.1 -1.3 -1.3 -1.6 -0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.5 0.5 3.1 -1.0 -1.1 0.6 1.8 -0.5 -0.2 0.8 0.8 -0.1 0.4 -0.3 0.5 0.0 -0.0 -0.1
Illnesses of father: Heart disease 2.9 4.0 6.8 1.6 0.2 2.2 1.4 1.1 -1.1 -2.4 -2.1 2.5 2.3 2.2 2.5 2.6 2.3 1.8
Illnesses of siblings: Diabetes 0.4 0.5 1.2 -0.4 -0.9 1.1 1.1 -0.8 -0.7 -0.5 -0.4 0.7 0.8 0.2 0.7 0.6 1.0 0.1
Smoking status: Previous 1.0 1.5 4.8 -1.8 -0.5 -0.5 -0.7 -1.3 -0.4 0.4 -0.2 -0.6 -1.8 -2.2 -1.4 -1.2 -1.3 -1.6
Forced expiratory volume in 1-second (FEV1), predicted 0.5 1.0 2.5 -0.2 -1.3 -0.1 1.1 1.0 -0.4 -0.6 -0.5 1.1 1.6 0.4 1.5 0.8 1.6 1.0
Whole body fat-free mass 0.7 4.0 12.0 0.7 -0.9 1.5 1.2 1.0 -2.9 -3.4 -3.5 2.4 1.5 1.2 1.5 1.5 2.7 0.8
Leg fat-free mass (right) 0.3 1.6 7.5 0.3 -0.4 0.6 0.3 0.0 -2.3 -2.4 -2.7 1.3 0.4 0.4 0.5 0.7 1.2 0.1
Arm fat percentage (left) 0.4 1.6 4.2 -0.5 0.9 -0.8 -1.1 -1.8 -0.6 0.6 -0.2 -1.0 -2.0 -1.3 -1.8 -1.4 -1.7 -1.3
Average weekly red wine intake 1.1 1.6 3.7 -1.1 0.1 -1.8 0.0 -0.7 0.2 1.7 0.9 -1.9 -1.3 -1.0 -1.5 -1.7 -1.3 -1.3
Handedness (chirality/laterality): Left-handed 1.6 2.0 4.4 1.9 0.9 1.9 -2.1 0.4 -1.8 -1.5 -1.4 0.9 0.7 2.0 1.0 1.2 0.5 1.2
Mood swings 1.2 2.1 5.5 -2.2 -1.5 -1.6 -0.1 -1.2 -0.9 1.0 0.3 -1.2 -1.3 -2.3 -1.4 -1.4 -1.7 -1.9
Loneliness, isolation 0.1 0.2 0.7 0.4 0.2 -0.4 -0.9 -0.7 -0.6 0.2 0.1 -0.6 -0.3 0.2 -0.2 -0.4 -0.4 0.1
Long-standing illness, disability or infirmity 0.5 0.7 5.0 -1.2 -0.5 -0.1 2.2 0.7 0.3 0.9 0.9 -0.1 0.4 -0.9 0.8 -0.1 0.1 0.5
Ever had bowel cancer screening 0.5 0.5 2.8 0.7 0.6 -0.1 0.4 -0.2 1.7 1.0 0.9 -1.1 -0.2 0.6 -0.2 -0.5 -0.5 0.4
Diabetes diagnosed by doctor 0.2 0.4 2.4 -0.3 -0.1 -0.8 -0.3 0.1 0.7 1.2 1.5 -0.5 0.4 -0.0 0.1 0.0 -0.3 -0.2
Ever had stillbirth, spontaneous miscarriage or termination 1.0 1.1 2.3 -0.8 -0.5 -0.5 -0.3 -0.7 0.5 0.9 0.1 -1.1 -1.5 -1.5 -1.5 -1.3 -1.4 -1.4
Friendships satisfaction 0.4 0.5 3.5 0.1 0.6 0.2 -1.9 0.4 -1.0 -0.8 -0.9 0.4 -0.4 -0.3 -0.4 -0.2 0.7 -0.2
Qualifications: nursing, teaching 2.0 3.0 12.7 3.1 3.6 1.9 -2.5 2.0 0.3 -0.8 -0.4 0.5 -0.1 2.1 0.4 0.6 0.4 1.9
Commuting to job workplace: Walk 0.6 0.7 2.1 -0.5 0.3 -0.4 1.4 -0.2 1.1 1.5 1.1 -1.0 -0.4 -0.4 -0.1 -0.8 -1.0 0.3
Eye problems/disorders: Cataract 0.8 0.9 2.2 0.3 1.1 -1.3 -0.8 -0.0 1.1 1.4 1.4 -1.1 -0.8 -0.2 -0.6 -0.7 -1.5 0.1
Mouth/teeth dental problems: Mouth ulcers 0.6 1.0 2.6 0.2 0.3 1.1 1.4 0.0 0.5 -0.2 0.3 1.0 1.4 0.9 1.6 1.4 1.0 1.3
Medication for cholesterol 0.2 0.3 1.8 0.5 0.4 0.1 -1.3 0.2 0.4 0.6 0.8 0.0 0.5 0.7 0.5 0.4 -0.1 0.8
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.1 0.1 0.7 -0.5 -0.4 -0.2 0.1 0.1 0.8 0.4 0.4 -0.2 0.1 -0.6 0.3 -0.2 -0.2 0.2
Back pain experienced in last month 1.3 1.9 5.8 -1.8 -2.1 -0.9 1.2 -2.4 -0.8 0.4 -0.2 -1.0 -1.1 -1.5 -1.4 -1.4 -0.6 -1.7
Mineral and other dietary supplements 0.2 0.3 1.1 1.1 0.7 0.3 -0.4 0.4 0.1 0.5 0.5 0.2 0.5 1.1 0.3 0.5 0.2 0.5
Breast cancer (self-reported) 2.5 3.0 7.4 -1.3 0.4 -1.5 -1.2 -1.5 0.8 1.9 1.3 -1.8 -2.3 -1.9 -2.2 -1.8 -2.7 -1.8
Asthma (self-reported) 2.2 4.3 10.4 1.4 -0.3 1.3 0.5 0.5 -1.5 -1.9 -1.1 2.9 3.2 2.3 2.9 3.0 3.0 1.9
Osteoporosis (self-reported) 3.5 4.3 9.0 -2.2 -1.0 -1.6 -0.1 -2.0 0.3 2.1 1.1 -2.6 -2.7 -2.4 -2.5 -2.7 -3.0 -2.2
Osteoarthritis (self-reported) 0.2 0.2 1.4 -0.8 -1.2 -0.0 0.6 -0.3 0.1 0.4 0.5 -0.2 0.6 -0.2 0.5 0.0 0.2 -0.1
Medication: Aspirin 0.2 0.2 1.0 -0.0 -0.5 0.5 0.8 0.8 -0.1 -0.6 -1.0 -0.1 0.2 0.3 0.1 0.1 0.3 -0.1
Medication: Gliclazide 1.9 2.2 5.1 -0.2 -0.3 -1.6 -0.9 -1.9 1.4 1.5 1.0 -2.1 -1.5 -0.5 -2.3 -1.8 -1.4 -1.7
Illnesses of father: None of the above (group 1) 2.0 2.5 6.5 -0.4 0.3 -1.0 -2.1 -0.8 0.0 1.1 0.6 -2.0 -2.4 -1.3 -2.6 -2.3 -2.0 -1.5
Smoking status: Current 1.2 2.0 5.6 -0.2 0.6 -0.7 2.3 1.2 2.4 2.1 2.3 -1.6 -0.5 -0.8 -0.1 -1.0 -1.5 0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.4 0.9 2.3 -1.5 -1.5 -0.5 1.4 -0.8 -0.1 -0.6 -0.7 0.5 -0.6 -1.3 -0.7 -0.2 0.2 -1.4
Whole body water mass 0.7 4.2 12.5 0.8 -0.8 1.5 1.1 1.0 -2.9 -3.5 -3.5 2.5 1.6 1.3 1.6 1.6 2.7 0.9
Leg predicted mass (right) 0.3 1.6 7.5 0.3 -0.5 0.6 0.3 0.0 -2.3 -2.4 -2.7 1.3 0.4 0.4 0.5 0.6 1.2 0.1
Arm fat mass (left) 0.2 0.7 3.5 -0.1 0.4 0.3 -0.2 -1.2 -1.9 -0.9 -1.6 0.1 -1.0 -0.4 -0.7 -0.4 -0.3 -0.7
Number of self-reported non-cancer illnesses 0.6 1.0 3.7 -0.9 -0.6 0.1 1.9 1.0 -0.5 -0.4 -0.1 1.6 1.1 -0.5 1.2 1.0 1.6 0.5
Average weekly champagne plus white wine intake 0.1 0.1 0.4 -0.1 -0.5 0.2 0.2 0.6 0.3 0.0 -0.0 -0.1 0.4 -0.0 0.2 -0.1 0.4 0.0
Miserableness 1.1 1.9 4.4 -0.8 -0.1 -0.7 -1.0 -1.3 -0.2 0.5 -0.4 -1.7 -2.1 -1.6 -2.0 -1.7 -2.1 -1.8
Guilty feelings 0.4 0.7 1.1 0.8 0.8 0.6 0.4 0.5 -0.9 -0.9 -0.9 0.9 0.6 1.0 0.8 0.8 1.0 1.0
Wears glasses or contact lenses 1.8 2.1 5.5 -1.2 0.6 -1.6 0.5 -1.0 2.3 1.8 1.6 -1.4 -1.5 -1.8 -1.4 -1.3 -1.4 -1.1
Ever taken oral contraceptive pill 0.5 0.5 2.0 0.1 -0.7 -0.1 1.4 -0.2 -0.7 -0.5 -0.2 0.9 0.9 0.6 0.7 1.0 0.8 0.2
Hearing aid user 0.3 0.3 1.4 -0.1 0.6 0.9 0.3 1.2 0.1 -0.3 0.2 0.7 0.2 -0.1 0.6 0.6 0.3 0.4
Mother’s age at death 0.9 1.1 5.5 1.5 0.5 0.9 -2.4 -0.8 -1.5 -1.0 -1.2 -0.2 -0.2 1.5 -0.6 -0.1 0.2 -0.0
Financial situation satisfaction 2.1 2.6 6.8 -1.4 -0.6 -1.3 -0.2 -1.4 0.6 1.3 0.3 -2.6 -2.1 -1.5 -2.0 -2.5 -2.2 -1.6
Tinnitus: Yes, now most or all of the time 0.4 0.4 2.1 -0.4 -1.1 -0.6 -0.2 0.2 -1.2 -0.8 -1.4 -0.1 0.3 -0.1 -0.0 -0.2 0.3 -0.5
Commuting to job workplace: Public transport 2.1 2.5 7.9 2.8 2.7 2.2 -2.3 1.7 0.5 -0.6 -0.5 0.1 0.1 2.1 0.5 0.4 0.5 1.9
Eye problems/disorders: Glaucoma 0.2 0.2 1.0 -0.1 0.4 0.1 0.1 0.6 1.0 0.5 1.0 -0.3 -0.0 -0.3 0.2 -0.2 -0.3 0.2
Medication: Blood pressure 0.1 0.1 0.5 0.0 -0.1 0.0 0.3 0.3 -0.4 -0.7 -0.6 0.7 0.2 0.0 0.1 0.5 0.4 -0.2
Pain type(s) experienced in last month: Hip pain 0.4 0.5 1.9 -0.9 -1.4 -0.5 1.2 -1.0 -0.9 0.2 -0.2 -0.7 0.0 -0.1 -0.3 -0.5 0.0 -0.7
Supplements: Fish oil (including cod liver oil) 0.2 0.3 0.8 -0.5 0.1 -0.6 0.3 -0.2 0.4 0.2 0.5 -0.6 -0.9 -0.9 -0.7 -0.8 -0.7 -0.2
High cholesterol (Self-reported) 0.6 1.1 5.9 1.0 0.4 0.5 0.1 -0.3 -2.2 -1.5 -2.4 0.4 -0.6 0.6 -0.8 -0.1 0.5 -0.5
Medication: Bendroflumethiazide 0.3 0.4 1.2 -0.1 0.8 0.1 -0.1 -0.1 0.1 1.0 1.0 -0.7 -0.6 -0.7 -0.3 -0.8 -1.1 0.1
Medication: Paracetamol 0.5 0.7 4.6 -1.4 -2.1 -0.3 -0.7 -0.9 -0.3 -0.4 0.2 0.4 0.7 -0.7 0.2 0.5 0.3 -1.1
Medication: Lisinopril 0.3 0.4 2.1 0.8 1.4 0.3 -0.5 0.1 0.8 0.3 0.1 -0.5 -0.8 0.2 -0.4 -0.4 -0.8 0.2
Medication: Atorvastatin 1.2 1.5 3.9 -1.5 -1.3 -1.8 0.0 -1.6 -0.4 -0.1 -0.5 -0.8 -1.3 -1.3 -1.8 -1.4 -0.1 -2.0
Illnesses of father: High blood pressure 0.3 0.4 0.9 -0.6 -0.2 -0.2 -0.1 -0.7 0.3 -0.1 -0.6 -0.7 -0.9 -0.8 -0.7 -0.7 -1.0 -0.8
Alcohol drinker status: Never 0.9 1.1 3.2 0.4 1.1 0.2 -1.0 -1.3 -0.5 -0.3 -0.8 -1.1 -1.8 0.1 -1.8 -1.0 -1.3 -1.2
Ever smoked 0.6 1.1 3.1 -1.5 -0.7 -0.7 0.7 -0.6 0.3 0.6 0.3 -1.0 -1.3 -1.8 -1.1 -1.2 -1.1 -1.2
Basal metabolic rate 0.6 3.2 10.9 0.6 -0.7 1.2 1.1 0.7 -2.9 -3.1 -3.3 2.1 1.1 0.9 1.2 1.2 2.2 0.6
Leg fat percentage (left) 0.3 1.2 3.9 -0.7 0.2 -0.6 0.0 -2.0 -0.8 0.7 -0.1 -1.2 -1.6 -1.0 -1.4 -1.3 -1.5 -1.2
Arm fat-free mass (left) 1.0 5.1 15.6 0.6 -1.1 1.7 1.6 0.7 -3.5 -3.9 -4.0 2.6 1.6 1.3 1.6 1.7 2.9 0.8
Number of operations (self-reported) 1.5 2.3 7.9 -2.7 -2.8 -2.7 0.9 -1.3 -0.9 0.5 0.6 0.3 0.2 -1.8 -0.6 -0.1 0.2 -2.0
Average weekly beer plus cider intake 0.7 1.0 5.7 -0.1 0.8 -0.0 -0.0 0.1 1.2 1.8 2.4 -0.9 -0.1 -0.3 0.4 -0.3 -1.3 0.7
Irritability 1.2 2.0 4.0 -1.3 0.9 -0.6 1.5 -0.1 0.3 2.0 1.5 -1.8 -2.0 -2.0 -1.2 -2.0 -1.6 -0.6
Risk taking 0.3 0.4 2.0 -0.5 -1.1 -0.2 0.7 -0.2 0.3 0.6 0.5 -1.4 0.1 -0.1 -0.1 -0.8 -0.4 -0.3
Ever had prostate specific antigen (PSA) test 2.2 2.5 7.6 2.2 2.3 2.0 -0.0 1.6 1.9 0.9 1.5 0.2 0.7 1.7 1.4 0.6 0.5 2.8
Fractured/broken bones in last 5 years 0.1 0.2 0.8 0.5 0.5 0.3 0.1 0.9 0.1 -0.4 -0.5 0.4 -0.0 0.1 0.3 0.2 0.0 0.5
Age started oral contraceptive pill 0.1 0.2 0.8 0.4 -0.0 -0.1 -0.7 -0.9 0.4 -0.2 -0.1 0.5 -0.1 0.1 -0.4 0.1 0.4 -0.3
Diastolic blood pressure, automated reading 0.9 2.7 9.8 -0.5 1.8 -0.3 0.9 -0.5 3.1 2.1 1.7 -1.6 -2.0 -1.7 -1.3 -1.6 -2.2 -0.3
Ever depressed for a whole week 0.4 0.5 1.9 -1.2 -0.3 0.1 0.8 0.4 1.4 0.2 0.4 0.1 -0.4 -1.3 -0.3 -0.1 -0.2 -0.9
Unable to work because of sickness or disability 0.7 0.9 3.9 -1.2 -0.8 -0.4 1.8 0.5 2.0 0.8 1.0 0.1 0.4 -1.1 0.4 0.1 -0.1 -0.2
Commuting to job workplace: Cycle 0.7 0.8 1.9 1.4 0.5 1.1 -1.2 0.0 -0.4 -1.4 -1.1 0.5 0.5 1.3 0.3 0.6 1.0 0.3
Myopia 0.7 1.0 4.8 1.0 2.2 1.5 -1.1 0.7 -0.5 0.6 0.4 -0.8 -1.2 0.1 -0.4 -0.6 -1.1 0.5
Vascular/heart problems diagnosed by doctor 0.4 1.0 4.2 -0.2 -2.0 -0.3 -0.5 -0.3 -1.0 -0.8 -0.5 1.0 1.7 0.6 0.9 1.0 1.4 -0.1
Cholesterol lowering medication 0.7 1.0 3.7 -1.2 -1.9 -1.3 1.8 -0.3 -0.3 -0.4 -0.9 -0.2 -0.0 -1.0 -0.6 -0.5 0.2 -1.3
Medication: Omeprazole (e.g. Zanprol) 0.3 0.4 1.9 -0.4 0.1 1.4 0.7 -0.3 -0.6 0.1 0.3 0.7 0.6 -0.2 1.0 0.8 0.3 0.4
Pain experienced in last month 1.3 2.2 5.8 2.1 2.4 1.4 -1.0 2.3 0.6 -0.2 0.0 0.9 1.0 1.7 1.6 1.3 0.7 2.1
Supplements: Calcium 0.4 0.5 3.6 -0.7 -0.6 0.1 -0.0 -0.6 -1.9 -0.8 -0.6 0.7 0.5 -0.1 0.6 0.6 0.3 -0.0
Basal cell carcinoma (self-reported) 0.4 0.5 1.9 -0.6 -1.1 -0.1 1.0 0.4 -1.4 -0.8 -0.6 0.6 0.5 -0.2 0.4 0.4 0.8 -0.0
Heart attack/myocardial infarction (self-reported) 0.6 0.8 2.7 0.4 -0.6 0.8 0.9 0.4 -1.6 -1.0 -1.2 0.8 1.0 0.9 1.1 0.9 0.7 0.7
Deep venous thrombosis (DVT) (self-reported) 2.1 2.7 5.7 1.4 -0.2 0.9 -0.3 1.5 -2.2 -2.4 -2.0 2.1 1.6 1.8 1.3 1.7 2.2 1.0
Heart disease (siblings) 0.8 1.0 2.7 -0.5 0.3 0.0 1.2 -1.7 1.2 0.2 -0.2 -0.9 -1.5 -1.0 -1.1 -0.9 -1.5 -0.9
Alcohol drinker status: Previous 3.0 3.4 7.6 -2.3 -0.9 -2.3 1.0 -1.8 0.7 1.5 1.0 -1.8 -1.9 -2.8 -2.0 -2.0 -2.0 -2.3
Pack years of smoking 1.5 2.2 5.0 -0.6 -0.9 -1.9 0.7 -2.0 0.7 1.1 0.7 -1.9 -1.6 -0.9 -2.2 -1.7 -1.5 -2.0
Impedance of whole body 1.6 8.0 32.0 -0.7 1.1 -2.7 -0.9 0.2 4.8 5.4 5.7 -3.0 -1.2 -1.3 -1.3 -1.9 -3.1 0.1
Leg fat mass (left) 0.2 0.6 2.6 -0.4 0.2 -0.1 0.3 -1.3 -1.6 -0.3 -0.9 -0.3 -1.0 -0.6 -0.8 -0.6 -0.7 -0.7
Arm predicted mass (left) 0.9 4.4 13.8 0.4 -1.3 1.3 1.5 0.5 -3.5 -3.6 -3.7 2.4 1.5 1.1 1.4 1.5 2.8 0.5