[Hub]/) : Traits : Impedance of leg (right) : ← →

chr10:95,019,584-98,649,296

Best TWAS P=1.67e-19 · Best GWAS P=3.31e-34 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
7	GTEx	Nerve Tibial	PLCE1	0.35	0.11	enet	25	0.23	2.1e-16	2.49	-9.0	1.7e-19	0.29	1.00	0.00	TRUE
11	GTEx	Skin Not Sun Exposed Suprapubic	PLCE1	0.11	0.09	lasso	2	0.07	7.1e-05	4.65	-7.7	1.9e-14	0.23	0.18	0.08	TRUE
18	The Cancer Genome Atlas	Breast Invasive Carcinoma	PLCE1	0.11	0.09	blup	166	0.10	1.1e-19	-3.09	-7.6	3.4e-14	0.20	1.00	0.00	TRUE
21	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	NOC3L	0.05	0.01	enet	5	0.03	6.3e-04	9.29	-7.2	7.4e-13	0.70	0.29	0.04	TRUE
8	GTEx	Ovary	HELLS	0.15	0.04	lasso	5	0.09	3.1e-03	-6.48	-6.5	6.1e-11	0.07	0.18	0.06	TRUE
16	METSIM	Adipose	HELLS	0.03	0.04	lasso	3	0.03	9.3e-05	-6.45	-6.5	9.2e-11	0.04	0.99	0.00	TRUE
13	GTEx	Testis	ZNF518A	0.27	0.15	enet	21	0.18	1.6e-08	-5.19	-6.3	3.2e-10	0.07	0.02	0.98	TRUE
15	GTEx	Thyroid	HELLS	0.07	0.00	enet	8	0.00	2.7e-01	-6.49	-6.2	7.6e-10	0.08	0.09	0.13	TRUE
24	The Cancer Genome Atlas	Prostate Adenocarcinoma	PLCE1	0.11	0.01	blup	167	0.05	3.9e-06	2.63	-6.1	1.0e-09	0.22	0.35	0.03	TRUE
4	GTEx	Brain Frontal Cortex BA9	HELLS	0.16	0.09	enet	20	0.15	1.0e-04	-5.27	-5.8	7.7e-09	0.09	0.56	0.03	TRUE
5	GTEx	Muscle Skeletal	NOC3L	0.09	0.05	enet	7	0.05	7.5e-06	-2.81	-5.4	7.5e-08	0.25	0.87	0.00	TRUE
22	The Cancer Genome Atlas	Brain Lower Grade Glioma	HELLS	0.03	0.03	lasso	3	0.02	5.7e-03	-5.64	-5.2	1.6e-07	0.00	0.25	0.53	TRUE
9	GTEx	Pancreas	NOC3L	0.21	0.14	lasso	6	0.17	1.5e-07	-4.62	-5.1	3.1e-07	0.35	0.35	0.26	TRUE
1	CommonMind	Brain Pre-frontal Cortex	HELLS	0.04	0.04	enet	12	0.04	5.1e-06	-6.47	-8.9	4.4e-19	0.23	0.97	0.00	FALSE
14	GTEx	Testis	PIPSL	0.14	0.00	enet	21	0.00	3.0e-01	-2.98	8.1	8.0e-16	-0.20	0.06	0.12	FALSE
25	The Cancer Genome Atlas	Prostate Adenocarcinoma	TBC1D12	0.04	0.04	blup	63	0.03	3.9e-04	-6.47	-7.6	2.5e-14	0.12	0.24	0.50	FALSE
26	The Cancer Genome Atlas	Thyroid Carcinoma	HELLS	0.05	0.02	blup	47	0.03	9.6e-04	-5.27	-7.6	3.4e-14	0.24	0.09	0.79	FALSE
17	The Cancer Genome Atlas	Breast Invasive Carcinoma	HELLS	0.04	0.01	blup	47	0.03	1.3e-06	-6.47	-7.1	1.5e-12	0.20	0.04	0.95	FALSE
20	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	HELLS	0.03	0.03	blup	47	0.03	1.7e-04	-5.27	-6.7	2.8e-11	0.08	0.42	0.47	FALSE
19	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	TBC1D12	0.04	0.01	blup	63	0.03	8.3e-03	-5.62	6.5	7.8e-11	0.03	0.08	0.04	FALSE
2	GTEx	Adrenal Gland	NOC3L	0.21	0.10	lasso	5	0.18	4.4e-07	0.57	-6.2	4.6e-10	0.80	0.04	0.96	FALSE
23	The Cancer Genome Atlas	Prostate Adenocarcinoma	HELLS	0.03	0.02	blup	47	0.03	2.1e-04	-5.63	-6.1	7.9e-10	0.12	0.06	0.88	FALSE
6	GTEx	Nerve Tibial	HELLS	0.12	0.12	enet	17	0.10	1.6e-07	-6.45	-5.9	3.2e-09	-0.09	1.00	0.00	FALSE
10	GTEx	Pituitary	CYP2C8	0.20	0.05	lasso	7	0.04	4.1e-02	-5.74	-5.9	4.6e-09	0.48	0.16	0.07	FALSE
3	GTEx	Brain Cerebellum	HELLS	0.26	0.20	lasso	9	0.19	2.8e-06	-5.73	-5.5	3.2e-08	-0.06	0.95	0.00	FALSE
12	GTEx	Skin Sun Exposed Lower leg	HELLS	0.05	0.02	lasso	3	0.00	1.2e-01	-5.64	-5.2	1.6e-07	-0.08	0.43	0.02	FALSE