TWAS hub - BRE

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Colon Sigmoid	0.1810	0.0810	0.0042	0.011	NA	0.046	NA	0.008	0.1300	NA	0.0098	NA	0.160
2	METSIM	Adipose	0.0287	0.0148	0.0110	-0.002	0.002	-0.001	0.001	-0.002	0.9800	0.13000	0.5100	0.19	0.840
3	TCGA	Liver Hepatocellular Carcinoma	0.1630	0.0660	0.0010	0.037	0.062	0.005	NA	0.031	0.0076	0.00072	0.1700	NA	0.013

Trait	Avg chi2 ratio	Avg chi2	Max chi2	2	3
Triglycerides	13.8	22.5	56.1	7.5	3.4
Fasting Glucose	8.9	10.6	29.7	-5.5	-1.5
Gout (self-reported)	6.9	9.5	23.7	4.9	2.2
Medication: Allopurinol	5.9	7.8	22.6	4.8	1.0
Qualifications: O levels/GCSEs or equivalent	4.9	7.7	13.8	-3.1	3.7
Medication: Cholesterol lowering	4.7	7.3	21.9	4.7	0.3
Average weekly spirits intake	4.1	5.1	9.3	3.0	-2.4
Alcohol intake frequency.	4.1	9.6	28.6	5.3	0.3
Medication: Simvastatin	3.9	5.8	16.9	4.1	-0.6
Glaucoma (self-reported)	3.9	4.6	13.5	-0.5	-3.7
High cholesterol (Self-reported)	3.9	7.0	20.4	4.5	0.8
Hayfever, allergic rhinitis or eczema	3.5	7.7	22.7	0.6	4.8
Impedance of arm (right)	3.5	16.2	48.4	7.0	0.5
Allergy	3.0	7.0	20.9	-0.3	-4.6
Impedance of arm (left)	3.0	14.0	41.7	6.5	0.5
Worrier / anxious feelings	2.9	5.6	9.1	-3.0	2.7
Smoking status: Previous	2.9	4.3	9.9	3.1	-1.7
Medication for cholesterol, blood pressure or diabetes	2.8	4.6	13.8	-3.7	0.1
Arm predicted mass (right)	2.8	14.2	31.2	-5.6	-3.4
Average weekly champagne plus white wine intake	2.8	3.8	9.4	-3.1	1.4
Impedance of whole body	2.8	14.0	41.9	6.5	0.4
Past tobacco smoking	2.7	4.9	11.6	-3.4	1.8
Mouth/teeth dental problems: Bleeding gums	2.7	3.6	7.5	1.8	2.7
Ever smoked	2.7	4.7	9.4	3.1	-2.2
Medication: Omeprazole (e.g. Zanprol)	2.7	3.3	6.0	-2.5	1.9
Blood White Count	2.6	19.6	33.5	5.8	5.0
Trunk fat-free mass	2.6	14.7	31.7	-5.6	-3.5
Arm fat-free mass (right)	2.6	13.4	28.0	-5.3	-3.5
Trunk predicted mass	2.5	14.5	30.6	-5.5	-3.6
Commuting to job workplace: Car/motor vehicle	2.5	2.8	8.4	2.9	0.2
Eye problems/disorders: Glaucoma	2.5	3.0	8.2	-0.8	-2.9
Schizophrenia (2014)	2.4	5.4	10.6	2.4	-3.2
Diabetes (father)	2.4	2.9	8.7	-2.9	-0.4
Whole body fat-free mass	2.4	13.5	29.9	-5.5	-3.2
Whole body water mass	2.4	13.6	29.7	-5.5	-3.3
Arm fat-free mass (left)	2.3	11.5	23.1	-4.8	-3.4
Arm predicted mass (left)	2.3	11.9	24.1	-4.9	-3.4
Bipolar Disorder or Schizophrenia	2.2	5.5	11.4	2.2	-3.4
Prostate Cancer	2.2	3.0	6.6	2.6	-1.6
Blood Platelet Count	2.2	25.0	70.9	8.4	2.0
Smoking Status	2.2	5.2	11.6	3.4	-2.0
Allergy or Eczema	2.2	5.9	17.3	0.6	4.2
Medication: Ventolin 100micrograms inhaler	2.2	2.9	5.8	-2.4	1.7
Depression (self-reported)	2.1	2.5	3.8	-1.9	1.9
Prospective memory result	2.1	2.5	5.9	1.3	-2.4
Angina	2.0	2.6	4.9	2.2	-1.7
Impedance of leg (right)	2.0	9.8	29.4	5.4	-0.2
Angina (self-reported)	2.0	2.7	5.5	2.4	-1.6
Medication: Aspirin	2.0	2.6	5.7	2.4	-1.5
Medication: Aspirin	2.0	2.7	5.3	2.3	-1.6
Basal metabolic rate	2.0	10.9	23.9	-4.9	-3.0
Fluid intelligence score	1.9	4.0	9.3	-3.0	1.6
Alcohol intake versus 10 years previously	1.9	2.8	8.0	2.8	0.7
Hair/balding pattern: Pattern 3	1.9	2.8	8.0	-0.8	-2.8
Loud music exposure frequency	1.9	2.1	3.8	1.6	-2.0
Leg predicted mass (right)	1.9	9.9	24.5	-5.0	-2.3
Bipolar Disorder (2011)	1.8	1.7	2.7	1.6	-1.6
Qualifications: None of the above	1.8	3.8	6.9	2.1	-2.6
Illnesses of siblings: Diabetes	1.8	2.2	6.5	-2.5	-0.4
Leg fat-free mass (right)	1.8	9.7	23.6	-4.9	-2.3
Number of self-reported non-cancer illnesses	1.8	3.2	7.4	2.7	1.5
Bipolar Disorder (2018)	1.7	2.7	4.4	2.1	-1.9
Diabetes (mother)	1.7	2.1	6.3	-0.2	-2.5
Leg fat-free mass (left)	1.7	8.8	19.9	-4.5	-2.6
Impedance of leg (left)	1.7	8.4	25.3	5.0	-0.0
Leg predicted mass (left)	1.7	8.8	19.5	-4.4	-2.6
Hearing difficulty/problems with background noise	1.7	2.7	7.1	2.7	1.0
Number of full brothers	1.7	2.2	4.2	2.0	-1.5
Health satisfaction	1.7	2.2	6.5	2.6	-0.1
Alcohol drinker status: Previous	1.7	2.0	5.6	2.4	-0.5
Crohns Disease (2017)	1.6	3.4	8.4	1.4	2.9
Blood Red Count	1.6	15.7	23.6	-4.9	4.9
Had major operations	1.6	1.9	4.9	2.2	-0.9
Medication: Atorvastatin	1.6	2.0	6.0	2.5	-0.2
Ever depressed for a whole week	1.6	2.0	3.4	1.8	-1.6
Schizophrenia (2018)	1.5	3.0	7.8	1.1	-2.8
Worry (Nagel 2018)	1.5	3.1	7.8	-2.8	1.3
Hearing difficulty/problems: Yes	1.5	2.3	6.7	2.6	-0.4
Pulse rate, automated reading	1.5	4.9	8.9	3.0	2.4
Friendships satisfaction	1.5	1.9	5.5	2.3	-0.3
Number of operations (self-reported)	1.5	2.2	5.9	2.4	0.8
Major Depression (MDD)	1.4	1.6	3.9	2.0	-1.0
Age when periods started (menarche)	1.4	3.3	7.8	1.4	-2.8
Medication: Amlodipine	1.4	2.0	5.3	2.3	-0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.4	1.6	4.8	-0.3	2.2
Ever taken oral contraceptive pill	1.4	1.6	3.6	-1.0	-1.9
Reaction Time	1.3	2.4	4.4	-1.7	2.1
Primary Biliary Cirrhosis	1.3	1.9	5.4	2.3	0.5
Height	1.3	24.4	69.2	-2.0	-8.3
Other serious medical condition/disability diagnosed by doctor	1.3	1.6	4.9	2.2	0.1
Maternal smoking around birth	1.3	1.8	4.1	2.0	-1.2
Noisy workplace	1.3	1.6	4.8	2.2	-0.3
Shortness of breath walking on level ground	1.3	1.5	4.5	0.3	-2.1
Chronotype (morning person)	1.2	2.7	7.3	-2.7	-0.9
Ever used hormone-replacement therapy (HRT)	1.2	1.5	4.0	-0.7	-2.0
Pain all over the body in last month	1.2	1.3	3.3	0.8	1.8
Medication: Omeprazole	1.2	1.5	3.3	-1.8	1.1
Comparative height size at age 10	1.2	6.6	12.0	-2.8	-3.5
Illnesses of father: None of the above (group 1)	1.2	1.5	2.4	-1.6	1.4
Body Mass Index (BMI) (2010)	1.1	1.5	4.1	2.0	-0.8
Crohns Disease (2012)	1.1	1.8	5.4	0.2	2.3
Hand grip strength (left)	1.1	2.9	6.4	-1.6	-2.5
Relative age of first facial hair	1.1	2.3	6.8	2.6	-0.5
Qualifications: A levels/AS levels or equivalent	1.1	2.4	5.7	-2.4	1.3
Medication: Seretide 50 evohaler	1.1	1.2	3.6	-1.9	0.3
Illness, injury, bereavement, stress in last 2 years	1.1	1.3	4.0	-0.0	2.0
Forced expiratory volume in 1-second (FEV1), predicted	1.1	2.4	4.9	-1.5	-2.2
Mean Putamen Volume	1.0	1.2	1.8	1.3	-1.3
Average weekly fortified wine intake	1.0	1.2	3.1	0.7	-1.8
Standing height	1.0	10.1	27.0	-1.8	-5.2
Peak expiratory flow (PEF)	1.0	2.4	6.8	-2.6	0.5
Worry too long after embarrassment	1.0	1.6	2.7	-1.5	1.7
Medication: Blood pressure	1.0	1.8	4.7	2.2	-0.9
Commuting to job workplace: Walk	1.0	1.1	2.8	-1.7	0.7
Commuting to job workplace: Public transport	1.0	1.2	3.6	-1.9	0.2
Commuting to job workplace: Cycle	1.0	1.3	2.5	-1.6	-1.1
Cholesterol lowering medication	1.0	1.5	4.5	2.1	-0.4
Systolic Blood Pressure	0.9	4.6	13.9	-0.1	3.7
Hand grip strength (right)	0.9	2.6	4.2	-1.9	-2.1
Had menopause	0.9	1.1	3.3	-0.2	-1.8
Falls in the last year	0.9	1.3	3.3	0.7	-1.8
Mouth/teeth dental problems: Dentures	0.9	1.6	4.5	-2.1	0.5
Birth weight of first child	0.9	1.6	3.7	-1.9	-1.1
Comparative body size at age 10	0.9	2.4	5.4	-1.4	2.3
Wheeze or whistling in the chest in last year	0.9	1.6	4.2	-0.8	2.0
Migraine (self-reported)	0.9	1.2	3.4	0.3	1.9
Asthma (self-reported)	0.9	1.8	5.0	-0.5	2.2
Basal cell carcinoma (self-reported)	0.9	1.1	2.0	-1.1	-1.4
Depression (Nagel 2018)	0.8	1.2	2.5	1.6	1.0
Age at First Birth	0.8	1.1	3.1	1.8	0.4
Coronary Artery Disease (CAD)	0.8	1.0	2.5	1.6	-0.7
Ulcerative Colitis	0.8	1.2	3.0	-0.7	1.7
Neuroticism	0.8	1.9	4.5	-1.1	2.1
Sitting height	0.8	5.8	9.8	-3.1	-2.8
Ever unenthusiastic/disinterested for a whole week	0.8	1.0	2.0	1.4	1.0
Diabetes (self-reported)	0.8	1.3	3.3	0.7	-1.8
Weight	0.8	4.1	6.2	-2.5	-2.5
Asthma	0.8	1.6	4.3	-0.8	2.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.8	2.6	6.8	-2.6	-0.9
Breastfed as a baby	0.8	1.0	2.3	1.5	-0.9
Overall health rating	0.8	1.7	4.6	0.7	2.1
Family relationship satisfaction	0.8	1.0	2.4	0.7	-1.6
Qualifications: NVQ or HND or HNC or equivalent	0.8	1.0	2.5	0.6	1.6
Ever had bowel cancer screening	0.8	0.9	2.0	0.8	1.4
Mineral and other dietary supplements	0.8	1.0	2.8	-1.7	0.5
Alzheimer’s Disease (in father)	0.7	0.8	1.4	1.0	-1.2
Irritable Bowel Disease (IBD)	0.7	1.7	4.5	0.8	2.1
Verbal and Numeric Reasoning (VNR)	0.7	1.6	4.9	-2.2	0.1
Ovarian Cancer	0.7	1.0	2.7	-1.6	0.5
Cardiovascular Disease	0.7	2.2	3.5	1.8	1.9
Number of treatments/medications taken	0.7	1.2	1.9	1.4	1.3
Medication: Co-codamol	0.7	0.8	1.6	1.3	-0.9
Serious illness, injury or assault to yourself	0.7	0.9	1.5	1.0	-1.2
Supplements: Glucosamine	0.7	0.9	2.6	1.6	0.2
Hair/balding pattern: Pattern 2	0.7	0.9	1.4	1.2	-1.2
Had other major operations	0.7	0.8	1.4	-1.2	1.1
Pulse rate	0.7	1.1	2.2	1.5	1.1
Blood clot in the leg (DVT)	0.7	0.9	2.2	1.5	-0.7
Illnesses of father: Heart disease	0.7	1.0	2.9	1.7	-0.2
Osteoarthritis (self-reported)	0.7	0.9	1.5	1.0	-1.2
Vascular/heart problems diagnosed by doctor	0.7	1.8	5.5	-2.3	0.1
Pack years of smoking	0.7	1.1	3.2	0.0	-1.8
Breast Cancer	0.6	1.4	3.7	0.6	-1.9
Type 2 Diabetes (T2D) (2012)	0.6	0.7	1.4	-1.2	0.8
Pack years adult smoking proportion	0.6	0.9	2.4	-0.6	-1.6
Taking other prescription medications	0.6	0.9	2.3	0.6	1.5
High blood pressure	0.6	1.6	4.6	2.1	0.6
Stomach or abdominal pain in last month	0.6	0.8	2.3	0.1	1.5
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	2.0	0.4	1.4
Alcohol usually taken with meals	0.6	1.0	2.0	1.4	1.1
Financial difficulties in last 2 years	0.6	0.8	1.7	0.8	-1.3
Time employed in main current job	0.6	0.7	1.5	0.8	1.2
Length of working week for main job	0.6	0.7	1.0	-1.0	-1.0
Forced vital capacity (FVC), Best measure	0.6	2.3	4.6	-2.1	-1.5
Miserableness	0.6	1.1	3.1	-0.3	1.8
Mother’s age at death	0.6	0.7	1.1	1.0	-1.0
Financial situation satisfaction	0.6	0.7	2.2	1.5	-0.2
Deep venous thrombosis (DVT) (self-reported)	0.6	0.8	1.9	1.4	-0.8
LDL Cholesterol	0.5	0.8	2.3	1.5	0.2
Systolic blood pressure, automated reading	0.5	1.3	2.8	-1.1	1.7
Townsend deprivation index at recruitment	0.5	0.6	1.4	0.7	-1.2
Mouth/teeth dental problems	0.5	0.7	2.1	0.1	-1.4
Neuroticism score	0.5	1.0	1.6	-1.2	1.2
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.7	2.0	-0.2	1.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.6	1.8	-0.4	-1.3
Pulse wave peak to peak time	0.5	0.6	1.9	-1.4	-0.2
Medication for pain relief, constipation, heartburn	0.5	0.9	2.7	-0.2	-1.6
Mean time to correctly identify matches	0.5	1.0	2.5	-0.6	1.6
Hypertension (Self-reported)	0.5	1.3	3.6	1.9	0.5
Diabetes diagnosed by doctor	0.5	0.9	2.6	-0.1	-1.6
Mouth/teeth dental problems: Mouth ulcers	0.5	0.7	2.2	0.1	1.5
Myopia	0.5	0.7	2.2	0.2	1.5
Heart disease (siblings)	0.5	0.7	1.1	0.9	-1.1
Intelligence (Savage-Jansen 2018)	0.4	1.1	2.6	-1.6	0.9
HDL Cholesterol	0.4	0.6	1.7	0.4	-1.3
Neuroticism (2016)	0.4	0.6	1.0	-1.0	0.9
Respiratory disease	0.4	0.8	2.3	-0.4	1.5
Hair Pigment	0.4	12.0	18.6	4.2	4.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	0.9	0.7	0.9
Number of incorrect matches in round	0.4	0.6	1.4	1.2	-0.7
Medication: Ramipril	0.4	0.5	1.3	1.2	-0.4
Hip circumference	0.4	1.9	4.0	-1.3	-2.0
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.7	1.4	-0.9	1.2
Forced expiratory volume in 1-second (FEV1)	0.4	1.5	4.4	-2.1	-0.3
Happiness	0.4	0.5	1.4	1.2	0.3
Pulse wave Arterial Stiffness index	0.4	0.5	1.4	1.2	-0.2
Chronic bronchitis/emphysema (mother)	0.4	0.5	1.1	0.5	-1.1
Exposure to tobacco smoke outside home	0.4	0.5	1.3	-1.1	0.6
Qualifications: College or University degree	0.4	1.1	2.6	-1.6	0.9
Suffer from ‘nerves’	0.4	0.6	1.9	-1.4	-0.2
Supplements: Vitamin C	0.4	0.4	0.7	0.8	0.8
Knee pain experienced in last month	0.4	0.7	1.0	1.0	-1.0
Average weekly red wine intake	0.4	0.5	1.2	-0.6	1.1
Eye problems/disorders: Cataract	0.4	0.5	1.4	0.0	1.2
Risk taking	0.4	0.6	1.6	0.5	-1.3
Age started oral contraceptive pill	0.4	0.6	1.2	-0.7	1.1
Alzheimer’s Disease (in mother)	0.3	0.4	1.2	-0.1	1.1
Lupus	0.3	0.4	1.2	-0.1	1.1
Rheumatoid Arthritis	0.3	0.4	0.8	0.5	-0.9
Blood Eosinophil Count	0.3	2.5	4.9	-2.2	1.6
Type 2 Diabetes (T2D) (2018)	0.3	0.6	1.6	-0.6	-1.2
Lung FEV1/FVC ratio	0.3	1.4	3.8	-1.9	0.6
Lung FVC	0.3	1.4	2.2	1.5	1.4
Tanning	0.3	3.9	10.8	-3.3	-0.9
Frequency of depressed mood in last 2 weeks	0.3	0.4	1.0	0.3	1.0
Vitamin and mineral supplements	0.3	0.4	0.8	-0.9	-0.7
Trunk fat percentage	0.3	1.4	4.0	2.0	-0.4
Bilateral oophorectomy (both ovaries removed)	0.3	0.4	1.2	1.1	0.1
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	0.8	-0.3	-0.9
Qualifications: CSEs or equivalent	0.3	0.3	0.7	0.6	0.8
Medication: Atenolol	0.3	0.4	1.0	-0.4	1.0
Waist circumference	0.3	0.9	2.3	-0.7	-1.5
Forced vital capacity (FVC)	0.3	1.0	1.9	-1.1	-1.4
Heart attack	0.3	0.4	1.1	0.2	-1.0
Father’s age at death	0.3	0.4	1.0	-0.3	1.0
Medication: Lansoprazole	0.3	0.4	1.0	-0.3	1.0
Illnesses of mother	0.3	0.4	0.8	-0.9	0.7
Medication: Paracetamol	0.3	0.5	1.0	1.0	0.7
Body fat percentage	0.3	1.2	3.5	1.9	-0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.3	0.6	-0.8	0.6
Eye problems/disorders: None of the above	0.3	0.3	0.5	-0.7	0.7
Heart disease (mother)	0.3	0.3	0.9	1.0	-0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.3	0.9	0.2	1.0
Number of full sisters	0.3	0.4	0.8	-0.9	0.5
Leg pain on walking	0.3	0.3	0.9	1.0	-0.3
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	0.8	-0.9	-0.1
Medication for cholesterol	0.3	0.4	1.0	-1.0	0.6
Back pain experienced in last month	0.3	0.4	0.8	-0.6	0.9
Breast cancer (self-reported)	0.3	0.4	0.6	-0.7	0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.6	1.6	0.5	1.3
Guilty feelings	0.3	0.5	1.4	-0.4	1.2
Pain type(s) experienced in last month: Hip pain	0.3	0.3	0.9	1.0	0.2
Supplements: Fish oil (including cod liver oil)	0.3	0.4	0.8	0.9	0.5
Medication: Bendroflumethiazide	0.3	0.5	1.0	1.0	-0.7
Alcohol drinker status: Never	0.3	0.3	0.8	0.4	0.9
Fractured/broken bones in last 5 years	0.3	0.4	1.1	-0.1	-1.1
Heart attack/myocardial infarction (self-reported)	0.3	0.4	1.1	0.4	-1.1
Depressed Affect (Nagel 2018)	0.2	0.5	1.3	0.3	1.1
Neuroticism (Nagel 2018)	0.2	0.6	1.3	-1.1	0.7
Alzheimer’s Disease (including proxy)	0.2	0.3	0.5	0.7	-0.6
BMI	0.2	1.4	3.9	-2.0	-0.4
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.7	0.3	0.8
Supplements: Zinc	0.2	0.2	0.5	0.7	-0.2
Medication: Metformin	0.2	0.3	0.8	0.3	-0.9
Severe depression (siblings)	0.2	0.2	0.5	0.7	0.4
Current tobacco smoking	0.2	0.3	0.5	0.7	-0.5
Body mass index (BMI)	0.2	1.0	3.1	-1.8	-0.1
Trunk fat mass	0.2	0.7	2.1	0.3	-1.4
Nervous feelings	0.2	0.4	1.0	-1.0	0.4
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	0.7	-0.5	0.8
Hayfever/allergic rhinitis (self-reported)	0.2	0.2	0.7	-0.0	0.9
Illnesses of siblings	0.2	0.2	0.7	0.1	0.8
Arm fat percentage (right)	0.2	0.7	1.9	1.4	0.4
Number of live births	0.2	0.3	0.6	0.5	0.8
Exposure to tobacco smoke at home	0.2	0.2	0.7	-0.1	0.8
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	0.7	-0.8	0.4
Pulse wave reflection index	0.2	0.2	0.6	-0.8	-0.2
Headache pain in last month	0.2	0.3	0.9	-0.0	0.9
Hypothyroidism/myxoedema (self-reported)	0.2	0.3	0.7	0.9	-0.5
Birth weight	0.2	0.5	0.9	-0.7	-0.9
High blood pressure (siblings)	0.2	0.2	0.7	0.8	0.1
Leg fat percentage (right)	0.2	0.7	2.0	1.4	-0.0
Emphysema/chronic bronchitis	0.2	0.2	0.3	-0.5	-0.6
Age at last live birth	0.2	0.2	0.5	0.7	-0.5
Loneliness, isolation	0.2	0.2	0.4	0.5	-0.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.3	0.5	0.6	0.7
Hearing aid user	0.2	0.3	0.8	0.1	0.9
Medication: Blood pressure	0.2	0.4	1.3	1.1	-0.1
Medication: Lisinopril	0.2	0.2	0.6	0.1	-0.8
Ever had prostate specific antigen (PSA) test	0.2	0.3	0.5	0.7	-0.5
Unable to work because of sickness or disability	0.2	0.2	0.6	-0.3	-0.8
Supplements: Calcium	0.2	0.2	0.5	0.7	0.3
Schizophrenia vs Biploar Disorder	0.1	0.2	0.6	-0.7	0.2
Heel T-Score	0.1	0.4	0.7	-0.8	0.7
Waist Hip Ratio (WHR)	0.1	0.4	0.9	0.9	0.6
Hypothyroidism (self reported)	0.1	0.2	0.6	-0.8	-0.1
Sensitivity / hurt feelings	0.1	0.1	0.3	-0.5	-0.2
Ever had hysterectomy (womb removed)	0.1	0.1	0.1	0.4	-0.3
Fed-up feelings	0.1	0.2	0.6	-0.4	0.7
Relative age voice broke	0.1	0.2	0.6	0.8	-0.1
Multivitamins +/- minerals	0.1	0.1	0.2	-0.4	-0.3
Medication: Levothyroxine sodium	0.1	0.2	0.6	0.1	0.8
High blood pressure (mother)	0.1	0.2	0.5	0.7	-0.4
Lung cancer (father)	0.1	0.1	0.3	0.0	0.5
Arm fat mass (right)	0.1	0.5	0.8	-0.8	-0.9
Tense / ‘highly strung’	0.1	0.2	0.4	-0.6	-0.6
Hair/balding pattern: Pattern 4	0.1	0.4	0.7	0.6	-0.9
Ever highly irritable/argumentative for 2 days	0.1	0.1	0.3	0.1	0.6
Mouth/teeth dental problems: Loose teeth	0.1	0.2	0.5	-0.2	0.7
Whole body fat mass	0.1	0.3	0.9	-0.0	-0.9
Leg fat mass (right)	0.1	0.4	1.1	-0.4	-1.0
Chest pain or discomfort	0.1	0.1	0.4	-0.1	0.6
Arm fat percentage (left)	0.1	0.4	1.2	1.1	0.3
Handedness (chirality/laterality): Left-handed	0.1	0.1	0.2	0.1	0.5
Qualifications: nursing, teaching	0.1	0.2	0.4	-0.2	0.7
Medication: Gliclazide	0.1	0.1	0.2	0.4	0.4
Smoking status: Current	0.1	0.2	0.5	0.7	-0.4
Arm fat mass (left)	0.1	0.5	1.0	-1.0	-0.8
Tinnitus: Yes, now most or all of the time	0.1	0.1	0.1	0.3	-0.4
Medication: Paracetamol	0.1	0.2	0.7	0.8	0.1
Leg fat percentage (left)	0.1	0.4	1.3	1.1	-0.1
Average weekly beer plus cider intake	0.1	0.2	0.3	-0.4	-0.6
Irritability	0.1	0.2	0.6	-0.8	-0.4
Diastolic blood pressure, automated reading	0.1	0.2	0.6	-0.8	0.3
Pain experienced in last month	0.1	0.2	0.5	-0.7	-0.4
Leg fat mass (left)	0.1	0.5	1.1	-0.6	-1.1
Ulcerative Colitis (UC)	0.0	0.1	0.2	-0.2	0.4
HbA1C	0.0	0.0	0.1	-0.1	-0.2
Medication for hormone replacement therapy	0.0	0.0	0.1	-0.2	-0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.0	0.1	0.2	-0.4	-0.0
Chronic bronchitis/emphysema (father)	0.0	0.0	0.1	0.1	-0.4
Heel bone mineral density (BMD) T-score, automated (right)	0.0	0.1	0.1	-0.2	0.4
Serious illness, injury or assault of a close relative in last 2 years	0.0	0.0	0.0	-0.2	-0.1
Number of children fathered	0.0	0.0	0.1	-0.4	-0.0
Age at first live birth	0.0	0.0	0.1	-0.2	0.1
Neck or shoulder pain in last month	0.0	0.0	0.0	0.2	0.2
Medication: Ibuprofen	0.0	0.0	0.1	0.1	0.3
Mood swings	0.0	0.0	0.1	0.1	0.2
Long-standing illness, disability or infirmity	0.0	0.0	0.1	0.3	0.1
Osteoporosis (self-reported)	0.0	0.0	0.0	0.0	-0.2
Wears glasses or contact lenses	0.0	0.0	0.1	0.1	0.2
Illnesses of father: High blood pressure	0.0	0.0	0.1	0.2	-0.2

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