[Hub]/) : Traits : Impedance of arm (right) :

chr1:153,493,615-155,910,830

Best TWAS P=6.61e-24 · Best GWAS P=1.1e-25 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Cerebellar Hemisphere DCST2 0.45 0.10 lasso 6 0.16 6.6e-05 4.61 -8.7 2.7e-18 0.14 0.07 0.74 FALSE
2 GTEx Brain Nucleus accumbens basal ganglia DCST2 0.28 0.04 lasso 5 0.13 2.0e-04 -10.06 -8.5 1.8e-17 0.19 0.10 0.38 FALSE
3 GTEx Brain Putamen basal ganglia DCST2 0.56 0.05 enet 11 0.10 2.8e-03 4.61 -5.5 3.6e-08 0.15 0.32 0.23 TRUE
4 GTEx Esophagus Mucosa MUC1 0.17 0.20 lasso 4 0.18 5.6e-12 6.09 5.5 4.7e-08 -0.28 1.00 0.00 TRUE
5 GTEx Pituitary KCNN3 0.41 0.31 lasso 6 0.28 7.4e-08 4.93 5.4 6.1e-08 -0.10 0.89 0.02 TRUE
6 GTEx Skin Sun Exposed Lower leg ADAM15 0.14 0.09 lasso 4 0.08 6.1e-07 -10.06 10.0 1.7e-23 -0.08 0.04 0.96 FALSE
7 GTEx Thyroid DCST2 0.16 0.12 lasso 2 0.11 6.4e-09 4.61 -6.1 1.1e-09 0.14 0.96 0.04 FALSE
8 GTEx Whole Blood ADAM15 0.10 0.00 lasso 13 0.00 1.5e-01 5.39 5.9 3.8e-09 -0.22 0.14 0.40 FALSE
9 GTEx Whole Blood C1orf43 0.10 0.00 enet 37 0.00 2.8e-01 2.95 5.6 2.7e-08 -0.05 0.02 0.70 TRUE
10 NTR Blood ZBTB7B 0.02 0.02 lasso 1 0.01 5.4e-05 -5.95 -6.0 2.6e-09 -0.01 0.89 0.00 FALSE
11 YFS Blood GBA 0.04 0.01 bslmm 321 0.02 3.9e-08 -3.81 -5.2 2.5e-07 0.38 0.98 0.00 FALSE
12 The Cancer Genome Atlas Colon Adenocarcinoma ADAM15 0.15 0.02 blup 49 0.08 1.4e-05 -10.31 7.8 4.1e-15 -0.29 0.00 0.86 TRUE
13 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma MUC1 0.04 0.01 enet 4 0.02 1.3e-03 6.09 5.3 8.6e-08 -0.18 0.04 0.03 FALSE
14 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma THBS3 0.04 0.01 blup 25 0.03 3.1e-04 -1.54 -5.2 1.6e-07 0.64 0.05 0.53 FALSE
15 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PBXIP1 0.06 0.06 enet 5 0.06 4.0e-07 4.89 -5.5 3.7e-08 0.16 0.01 0.99 TRUE
16 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma ADAM15 0.09 0.00 blup 49 0.02 3.6e-02 3.50 8.2 2.7e-16 -0.24 0.01 0.11 FALSE
17 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma THBS3 0.04 0.02 enet 8 0.01 4.5e-02 -1.57 -5.5 3.2e-08 0.51 0.02 0.32 FALSE
18 The Cancer Genome Atlas Brain Lower Grade Glioma ADAM15 0.07 0.00 enet 12 0.04 6.1e-05 -10.31 5.4 8.1e-08 -0.19 0.01 0.86 FALSE
19 The Cancer Genome Atlas Lung Squamous Cell Carcinoma ZBTB7B 0.05 0.06 lasso 2 0.05 1.8e-06 -10.06 10.1 6.6e-24 -0.07 0.01 0.99 TRUE
20 The Cancer Genome Atlas Pancreatic Adenocarcinoma AQP10 0.12 0.01 blup 37 0.04 7.1e-03 2.68 -5.2 2.3e-07 -0.02 0.00 0.54 FALSE
21 The Cancer Genome Atlas Prostate Adenocarcinoma GBA 0.05 0.01 lasso 2 0.01 2.3e-02 -10.48 10.0 1.3e-23 -0.93 0.00 0.87 TRUE
22 The Cancer Genome Atlas Thyroid Carcinoma THBS3 0.14 0.03 enet 16 0.08 3.8e-08 0.42 -5.7 1.3e-08 0.69 0.00 0.99 TRUE