[Hub]/) : Traits : Impedance of arm (right) : ← →

chr1:149,672,809-152,126,467

Best TWAS P=1.94e-50 · Best GWAS P=1.75e-72 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
11	GTEx	Artery Tibial	RP11-196G18.22	0.25	0.05	lasso	5	0.07	1.8e-06	11.4	14.9	1.9e-50	0.78	0.01	0.98	TRUE
39	GTEx	Thyroid	ANP32E	0.08	0.00	enet	15	0.01	8.6e-02	-6.9	11.2	6.7e-29	0.37	0.04	0.11	TRUE
26	GTEx	Lung	MTMR11	0.08	0.04	lasso	8	0.03	3.0e-03	-10.4	-10.1	5.0e-24	-0.29	0.19	0.11	TRUE
23	GTEx	Heart Left Ventricle	MTMR11	0.11	0.05	lasso	3	0.05	9.3e-04	-10.8	-9.6	9.9e-22	-0.39	0.20	0.13	TRUE
58	The Cancer Genome Atlas	Brain Lower Grade Glioma	SV2A	0.04	0.00	blup	9	0.03	5.5e-04	-10.3	-9.3	1.7e-20	-0.21	0.00	0.33	TRUE
70	The Cancer Genome Atlas	Thyroid Carcinoma	SELENBP1	0.06	0.02	enet	7	0.05	2.3e-05	-5.4	-7.8	7.7e-15	-0.13	0.12	0.81	TRUE
47	YFS	Blood	MCL1	0.07	0.03	bslmm	278	0.03	4.4e-10	5.5	-7.5	4.7e-14	-0.10	1.00	0.00	TRUE
31	GTEx	Skin Sun Exposed Lower leg	GABPB2	0.12	0.01	enet	16	0.04	1.8e-04	6.7	-6.4	1.5e-10	-0.03	0.06	0.60	TRUE
60	The Cancer Genome Atlas	Lung Adenocarcinoma	PIP5K1A	0.03	0.01	blup	36	0.02	5.1e-03	-6.3	-6.1	1.0e-09	-0.13	0.06	0.32	TRUE
53	The Cancer Genome Atlas	Esophageal Carcinoma	PIP5K1A	0.10	0.06	lasso	1	0.04	2.1e-02	-5.9	-6.0	2.7e-09	-0.16	0.03	0.13	TRUE
4	GTEx	Adipose Subcutaneous	RP11-196G18.22	0.13	0.02	enet	16	0.06	6.4e-06	1.7	5.3	1.1e-07	0.44	0.10	0.15	TRUE
10	GTEx	Artery Tibial	HIST2H2AA3	0.22	0.02	enet	20	0.12	1.8e-09	16.8	14.3	1.7e-46	0.70	0.00	1.00	FALSE
12	GTEx	Artery Tibial	RP11-196G18.24	0.31	0.08	enet	26	0.10	6.1e-08	16.8	12.6	1.3e-36	0.72	0.00	0.99	FALSE
22	GTEx	Esophagus Muscularis	BOLA1	0.07	0.00	lasso	4	0.00	2.5e-01	-10.8	12.3	9.6e-35	0.43	0.03	0.13	FALSE
65	The Cancer Genome Atlas	Prostate Adenocarcinoma	SF3B4	0.03	0.02	blup	10	0.01	1.4e-02	-10.4	-11.4	3.7e-30	-0.32	0.04	0.16	FALSE
2	GTEx	Adipose Subcutaneous	MTMR11	0.08	0.04	lasso	4	0.05	3.5e-05	-10.4	-11.4	5.3e-30	-0.37	0.78	0.03	FALSE
64	The Cancer Genome Atlas	Prostate Adenocarcinoma	MTMR11	0.02	0.02	lasso	3	0.02	3.7e-03	-10.4	-10.5	6.0e-26	-0.30	0.03	0.03	FALSE
56	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SV2A	0.05	0.02	blup	9	0.03	2.5e-04	-10.8	10.3	8.7e-25	0.48	0.03	0.08	FALSE
37	GTEx	Thyroid	MTMR11	0.09	0.05	enet	9	0.06	1.5e-05	-10.8	-9.7	3.7e-22	-0.40	0.26	0.42	FALSE
7	GTEx	Artery Aorta	RPRD2	0.08	-0.01	enet	19	0.00	4.2e-01	-4.3	9.1	9.3e-20	0.30	0.08	0.26	FALSE
67	The Cancer Genome Atlas	Skin Cutaneous Melanoma	FCGR1A	0.10	0.03	lasso	4	0.04	3.9e-02	-10.8	8.6	7.7e-18	0.38	0.01	0.07	FALSE
46	METSIM	Adipose	TMOD4	0.02	0.00	blup	312	0.01	3.2e-02	-7.0	8.6	9.6e-18	0.11	0.03	0.63	FALSE
30	GTEx	Skin Sun Exposed Lower leg	MTMR11	0.03	0.01	lasso	5	0.00	1.2e-01	-10.8	-8.5	2.7e-17	-0.39	0.05	0.05	FALSE
55	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PSMB4	0.03	0.00	blup	37	0.02	7.0e-03	-5.4	7.6	2.6e-14	0.13	0.05	0.38	FALSE
66	The Cancer Genome Atlas	Prostate Adenocarcinoma	SV2A	0.11	0.10	blup	9	0.11	3.8e-11	-3.1	7.5	7.9e-14	0.40	1.00	0.00	FALSE
44	METSIM	Adipose	RP11-196G18.24	0.27	0.01	blup	116	0.13	3.6e-19	4.2	7.4	1.2e-13	0.31	0.04	0.94	FALSE
51	The Cancer Genome Atlas	Breast Invasive Carcinoma	SV2A	0.03	0.02	enet	3	0.02	8.0e-06	-3.1	7.0	3.0e-12	0.38	0.13	0.23	FALSE
57	The Cancer Genome Atlas	Brain Lower Grade Glioma	PIP5K1A	0.02	0.02	lasso	3	0.02	6.2e-03	-6.8	-6.9	6.1e-12	-0.19	0.04	0.63	FALSE
48	YFS	Blood	PRUNE	0.05	0.00	enet	33	0.02	5.8e-06	-4.3	-6.8	8.1e-12	-0.06	0.09	0.29	FALSE
52	The Cancer Genome Atlas	Colon Adenocarcinoma	PIP5K1A	0.05	0.03	blup	35	0.04	4.0e-03	-6.8	-6.7	1.7e-11	-0.19	0.03	0.82	FALSE
63	The Cancer Genome Atlas	Prostate Adenocarcinoma	ENSA	0.02	0.01	enet	3	0.01	2.5e-02	-4.7	6.7	2.1e-11	0.08	0.01	0.68	FALSE
43	METSIM	Adipose	PSMD4	0.03	0.05	lasso	4	0.04	6.1e-07	-6.2	6.5	6.6e-11	0.22	0.12	0.88	FALSE
38	GTEx	Thyroid	PRUNE	0.11	0.00	enet	21	0.03	3.1e-03	-2.1	-6.5	7.9e-11	-0.07	0.42	0.04	FALSE
59	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	MTMR11	0.12	0.09	blup	11	0.10	1.3e-05	-10.8	-6.5	1.1e-10	-0.18	0.07	0.11	FALSE
50	The Cancer Genome Atlas	Breast Invasive Carcinoma	PIP5K1A	0.04	0.05	lasso	6	0.05	8.8e-10	-6.1	-6.3	3.4e-10	-0.15	0.29	0.71	FALSE
45	METSIM	Adipose	SCNM1	0.06	0.06	lasso	10	0.05	3.6e-08	5.8	6.3	3.6e-10	0.14	0.76	0.24	FALSE
32	GTEx	Skin Sun Exposed Lower leg	SV2A	0.07	0.00	enet	15	0.02	6.0e-03	-3.1	-6.2	6.2e-10	-0.16	0.07	0.12	FALSE
69	The Cancer Genome Atlas	Thyroid Carcinoma	PIP5K1A	0.04	0.06	lasso	2	0.05	9.7e-06	-6.1	-6.2	7.4e-10	-0.15	0.24	0.72	FALSE
42	METSIM	Adipose	POGZ	0.06	0.05	lasso	12	0.03	9.3e-06	-5.4	-6.2	7.6e-10	-0.05	0.97	0.02	FALSE
33	GTEx	Spleen	RP11-54A4.2	0.29	0.10	lasso	9	0.04	3.8e-02	-6.0	6.2	8.0e-10	0.04	0.31	0.04	FALSE
49	YFS	Blood	SCNM1	0.09	0.04	enet	62	0.08	1.3e-24	-6.1	6.0	2.5e-09	0.05	0.36	0.64	FALSE
24	GTEx	Heart Left Ventricle	CERS2	0.08	0.02	enet	9	0.03	1.7e-02	-4.2	5.8	5.2e-09	0.08	0.17	0.19	FALSE
40	GTEx	Thyroid	SELENBP1	0.23	0.19	enet	12	0.23	2.3e-17	-5.3	-5.8	8.6e-09	0.01	0.95	0.05	FALSE
6	GTEx	Adrenal Gland	CTSS	0.12	0.13	lasso	9	0.08	7.0e-04	-6.0	-5.6	2.1e-08	0.00	0.62	0.20	FALSE
34	GTEx	Stomach	CTSS	0.05	0.02	enet	16	0.00	2.8e-01	-4.2	-5.6	2.4e-08	-0.01	0.14	0.43	FALSE
68	The Cancer Genome Atlas	Stomach Adenocarcinoma	POGZ	0.04	0.01	blup	43	0.01	3.7e-02	-5.0	-5.6	2.5e-08	0.02	0.03	0.18	FALSE
8	GTEx	Artery Tibial	ARNT	0.09	0.07	lasso	3	0.06	1.5e-05	5.5	-5.6	2.6e-08	-0.07	0.11	0.85	FALSE
14	GTEx	Brain Hippocampus	ARNT	0.14	0.09	enet	14	0.08	5.3e-03	-3.5	-5.6	2.6e-08	0.00	0.10	0.08	FALSE
54	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	GOLPH3L	0.12	0.16	blup	49	0.16	4.8e-18	-4.7	5.5	3.4e-08	0.07	1.00	0.00	FALSE
27	GTEx	Muscle Skeletal	CTSS	0.04	0.01	enet	13	0.03	1.4e-03	-5.3	-5.5	4.3e-08	-0.01	0.47	0.08	FALSE
13	GTEx	Brain Cerebellar Hemisphere	RP11-316M1.12	0.31	0.37	lasso	4	0.39	4.5e-11	-4.2	5.4	5.8e-08	0.01	0.98	0.02	FALSE
15	GTEx	Brain Hypothalamus	RP11-316M1.12	0.14	0.03	lasso	6	0.02	9.9e-02	-5.2	5.4	6.3e-08	0.09	0.11	0.09	FALSE
3	GTEx	Adipose Subcutaneous	POGZ	0.08	0.05	lasso	5	0.04	3.4e-04	-5.4	-5.4	7.1e-08	-0.02	0.40	0.04	FALSE
62	The Cancer Genome Atlas	Prostate Adenocarcinoma	ARNT	0.06	0.02	lasso	3	0.02	1.4e-03	5.5	-5.4	7.1e-08	-0.05	0.02	0.92	FALSE
1	CommonMind	Brain Pre-frontal Cortex	PSMB4	0.09	0.07	lasso	1	0.06	4.8e-08	-5.4	-5.4	8.2e-08	-0.02	0.97	0.03	FALSE
5	GTEx	Adipose Visceral Omentum	POGZ	0.12	0.04	enet	14	0.04	2.6e-03	-5.4	-5.3	1.0e-07	-0.05	0.67	0.08	FALSE
9	GTEx	Artery Tibial	POGZ	0.15	0.13	lasso	5	0.10	4.6e-08	-5.2	-5.3	1.1e-07	-0.03	0.98	0.02	FALSE
28	GTEx	Nerve Tibial	POGZ	0.18	0.16	lasso	2	0.15	1.6e-10	-5.3	-5.3	1.1e-07	-0.02	0.98	0.02	FALSE
17	GTEx	Cells Transformed fibroblasts	POGZ	0.16	0.12	lasso	5	0.12	4.1e-09	-5.4	-5.3	1.3e-07	-0.01	0.98	0.02	FALSE
18	GTEx	Cells Transformed fibroblasts	PSMB4	0.14	0.06	lasso	5	0.03	1.2e-03	-5.4	5.3	1.4e-07	0.04	0.93	0.03	FALSE
16	GTEx	Cells EBV-transformed lymphocytes	CDC42SE1	0.39	0.09	lasso	7	0.05	7.9e-03	-4.8	-5.3	1.5e-07	0.09	0.09	0.06	FALSE
19	GTEx	Colon Transverse	SV2A	0.09	0.00	lasso	9	0.00	2.2e-01	-3.8	5.2	1.9e-07	0.22	0.05	0.12	FALSE
29	GTEx	Skin Not Sun Exposed Suprapubic	POGZ	0.09	0.09	lasso	3	0.06	3.1e-04	-5.2	-5.2	2.0e-07	-0.03	0.57	0.04	FALSE
36	GTEx	Testis	POGZ	0.22	0.18	enet	11	0.16	1.1e-07	-5.4	-5.2	2.1e-07	-0.02	0.98	0.02	FALSE
61	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	MRPS21	0.04	0.03	blup	15	0.04	4.0e-05	1.9	-5.2	2.1e-07	0.02	0.09	0.03	FALSE
41	GTEx	Thyroid	ARNT	0.08	0.10	lasso	10	0.10	7.8e-08	4.1	-5.2	2.2e-07	-0.05	0.94	0.06	FALSE
35	GTEx	Testis	CTSK	0.07	0.01	enet	19	0.01	1.2e-01	-4.1	-5.2	2.4e-07	-0.03	0.28	0.27	FALSE
25	GTEx	Liver	RP11-316M1.12	0.27	0.33	lasso	5	0.37	2.9e-11	-4.2	5.1	2.7e-07	0.00	0.99	0.01	FALSE
20	GTEx	Esophagus Gastroesophageal Junction	RP11-316M1.12	0.25	0.40	lasso	8	0.41	4.4e-16	-4.2	5.1	2.8e-07	0.01	1.00	0.00	FALSE
21	GTEx	Esophagus Mucosa	C1orf56	0.07	0.06	enet	7	0.06	5.1e-05	-5.0	5.1	2.9e-07	-0.07	0.76	0.02	FALSE