[Hub]/) : Traits : Impedance of arm (right) :

chr1:149,672,809-152,126,467

Best TWAS P=1.94e-50 · Best GWAS P=1.75e-72 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PSMB4 0.09 0.07 lasso 1 0.06 4.8e-08 -5.4 -5.4 8.2e-08 -0.02 0.97 0.03 FALSE
2 GTEx Adipose Subcutaneous MTMR11 0.08 0.04 lasso 4 0.05 3.5e-05 -10.4 -11.4 5.3e-30 -0.37 0.78 0.03 FALSE
3 GTEx Adipose Subcutaneous POGZ 0.08 0.05 lasso 5 0.04 3.4e-04 -5.4 -5.4 7.1e-08 -0.02 0.40 0.04 FALSE
4 GTEx Adipose Subcutaneous RP11-196G18.22 0.13 0.02 enet 16 0.06 6.4e-06 1.7 5.3 1.1e-07 0.44 0.10 0.15 TRUE
5 GTEx Adipose Visceral Omentum POGZ 0.12 0.04 enet 14 0.04 2.6e-03 -5.4 -5.3 1.0e-07 -0.05 0.67 0.08 FALSE
6 GTEx Adrenal Gland CTSS 0.12 0.13 lasso 9 0.08 7.0e-04 -6.0 -5.6 2.1e-08 0.00 0.62 0.20 FALSE
7 GTEx Artery Aorta RPRD2 0.08 -0.01 enet 19 0.00 4.2e-01 -4.3 9.1 9.3e-20 0.30 0.08 0.26 FALSE
8 GTEx Artery Tibial ARNT 0.09 0.07 lasso 3 0.06 1.5e-05 5.5 -5.6 2.6e-08 -0.07 0.11 0.85 FALSE
9 GTEx Artery Tibial POGZ 0.15 0.13 lasso 5 0.10 4.6e-08 -5.2 -5.3 1.1e-07 -0.03 0.98 0.02 FALSE
10 GTEx Artery Tibial HIST2H2AA3 0.22 0.02 enet 20 0.12 1.8e-09 16.8 14.3 1.7e-46 0.70 0.00 1.00 FALSE
11 GTEx Artery Tibial RP11-196G18.22 0.25 0.05 lasso 5 0.07 1.8e-06 11.4 14.9 1.9e-50 0.78 0.01 0.98 TRUE
12 GTEx Artery Tibial RP11-196G18.24 0.31 0.08 enet 26 0.10 6.1e-08 16.8 12.6 1.3e-36 0.72 0.00 0.99 FALSE
13 GTEx Brain Cerebellar Hemisphere RP11-316M1.12 0.31 0.37 lasso 4 0.39 4.5e-11 -4.2 5.4 5.8e-08 0.01 0.98 0.02 FALSE
14 GTEx Brain Hippocampus ARNT 0.14 0.09 enet 14 0.08 5.3e-03 -3.5 -5.6 2.6e-08 0.00 0.10 0.08 FALSE
15 GTEx Brain Hypothalamus RP11-316M1.12 0.14 0.03 lasso 6 0.02 9.9e-02 -5.2 5.4 6.3e-08 0.09 0.11 0.09 FALSE
16 GTEx Cells EBV-transformed lymphocytes CDC42SE1 0.39 0.09 lasso 7 0.05 7.9e-03 -4.8 -5.3 1.5e-07 0.09 0.09 0.06 FALSE
17 GTEx Cells Transformed fibroblasts POGZ 0.16 0.12 lasso 5 0.12 4.1e-09 -5.4 -5.3 1.3e-07 -0.01 0.98 0.02 FALSE
18 GTEx Cells Transformed fibroblasts PSMB4 0.14 0.06 lasso 5 0.03 1.2e-03 -5.4 5.3 1.4e-07 0.04 0.93 0.03 FALSE
19 GTEx Colon Transverse SV2A 0.09 0.00 lasso 9 0.00 2.2e-01 -3.8 5.2 1.9e-07 0.22 0.05 0.12 FALSE
20 GTEx Esophagus Gastroesophageal Junction RP11-316M1.12 0.25 0.40 lasso 8 0.41 4.4e-16 -4.2 5.1 2.8e-07 0.01 1.00 0.00 FALSE
21 GTEx Esophagus Mucosa C1orf56 0.07 0.06 enet 7 0.06 5.1e-05 -5.0 5.1 2.9e-07 -0.07 0.76 0.02 FALSE
22 GTEx Esophagus Muscularis BOLA1 0.07 0.00 lasso 4 0.00 2.5e-01 -10.8 12.3 9.6e-35 0.43 0.03 0.13 FALSE
23 GTEx Heart Left Ventricle MTMR11 0.11 0.05 lasso 3 0.05 9.3e-04 -10.8 -9.6 9.9e-22 -0.39 0.20 0.13 TRUE
24 GTEx Heart Left Ventricle CERS2 0.08 0.02 enet 9 0.03 1.7e-02 -4.2 5.8 5.2e-09 0.08 0.17 0.19 FALSE
25 GTEx Liver RP11-316M1.12 0.27 0.33 lasso 5 0.37 2.9e-11 -4.2 5.1 2.7e-07 0.00 0.99 0.01 FALSE
26 GTEx Lung MTMR11 0.08 0.04 lasso 8 0.03 3.0e-03 -10.4 -10.1 5.0e-24 -0.29 0.19 0.11 TRUE
27 GTEx Muscle Skeletal CTSS 0.04 0.01 enet 13 0.03 1.4e-03 -5.3 -5.5 4.3e-08 -0.01 0.47 0.08 FALSE
28 GTEx Nerve Tibial POGZ 0.18 0.16 lasso 2 0.15 1.6e-10 -5.3 -5.3 1.1e-07 -0.02 0.98 0.02 FALSE
29 GTEx Skin Not Sun Exposed Suprapubic POGZ 0.09 0.09 lasso 3 0.06 3.1e-04 -5.2 -5.2 2.0e-07 -0.03 0.57 0.04 FALSE
30 GTEx Skin Sun Exposed Lower leg MTMR11 0.03 0.01 lasso 5 0.00 1.2e-01 -10.8 -8.5 2.7e-17 -0.39 0.05 0.05 FALSE
31 GTEx Skin Sun Exposed Lower leg GABPB2 0.12 0.01 enet 16 0.04 1.8e-04 6.7 -6.4 1.5e-10 -0.03 0.06 0.60 TRUE
32 GTEx Skin Sun Exposed Lower leg SV2A 0.07 0.00 enet 15 0.02 6.0e-03 -3.1 -6.2 6.2e-10 -0.16 0.07 0.12 FALSE
33 GTEx Spleen RP11-54A4.2 0.29 0.10 lasso 9 0.04 3.8e-02 -6.0 6.2 8.0e-10 0.04 0.31 0.04 FALSE
34 GTEx Stomach CTSS 0.05 0.02 enet 16 0.00 2.8e-01 -4.2 -5.6 2.4e-08 -0.01 0.14 0.43 FALSE
35 GTEx Testis CTSK 0.07 0.01 enet 19 0.01 1.2e-01 -4.1 -5.2 2.4e-07 -0.03 0.28 0.27 FALSE
36 GTEx Testis POGZ 0.22 0.18 enet 11 0.16 1.1e-07 -5.4 -5.2 2.1e-07 -0.02 0.98 0.02 FALSE
37 GTEx Thyroid MTMR11 0.09 0.05 enet 9 0.06 1.5e-05 -10.8 -9.7 3.7e-22 -0.40 0.26 0.42 FALSE
38 GTEx Thyroid PRUNE 0.11 0.00 enet 21 0.03 3.1e-03 -2.1 -6.5 7.9e-11 -0.07 0.42 0.04 FALSE
39 GTEx Thyroid ANP32E 0.08 0.00 enet 15 0.01 8.6e-02 -6.9 11.2 6.7e-29 0.37 0.04 0.11 TRUE
40 GTEx Thyroid SELENBP1 0.23 0.19 enet 12 0.23 2.3e-17 -5.3 -5.8 8.6e-09 0.01 0.95 0.05 FALSE
41 GTEx Thyroid ARNT 0.08 0.10 lasso 10 0.10 7.8e-08 4.1 -5.2 2.2e-07 -0.05 0.94 0.06 FALSE
42 METSIM Adipose POGZ 0.06 0.05 lasso 12 0.03 9.3e-06 -5.4 -6.2 7.6e-10 -0.05 0.97 0.02 FALSE
43 METSIM Adipose PSMD4 0.03 0.05 lasso 4 0.04 6.1e-07 -6.2 6.5 6.6e-11 0.22 0.12 0.88 FALSE
44 METSIM Adipose RP11-196G18.24 0.27 0.01 blup 116 0.13 3.6e-19 4.2 7.4 1.2e-13 0.31 0.04 0.94 FALSE
45 METSIM Adipose SCNM1 0.06 0.06 lasso 10 0.05 3.6e-08 5.8 6.3 3.6e-10 0.14 0.76 0.24 FALSE
46 METSIM Adipose TMOD4 0.02 0.00 blup 312 0.01 3.2e-02 -7.0 8.6 9.6e-18 0.11 0.03 0.63 FALSE
47 YFS Blood MCL1 0.07 0.03 bslmm 278 0.03 4.4e-10 5.5 -7.5 4.7e-14 -0.10 1.00 0.00 TRUE
48 YFS Blood PRUNE 0.05 0.00 enet 33 0.02 5.8e-06 -4.3 -6.8 8.1e-12 -0.06 0.09 0.29 FALSE
49 YFS Blood SCNM1 0.09 0.04 enet 62 0.08 1.3e-24 -6.1 6.0 2.5e-09 0.05 0.36 0.64 FALSE
50 The Cancer Genome Atlas Breast Invasive Carcinoma PIP5K1A 0.04 0.05 lasso 6 0.05 8.8e-10 -6.1 -6.3 3.4e-10 -0.15 0.29 0.71 FALSE
51 The Cancer Genome Atlas Breast Invasive Carcinoma SV2A 0.03 0.02 enet 3 0.02 8.0e-06 -3.1 7.0 3.0e-12 0.38 0.13 0.23 FALSE
52 The Cancer Genome Atlas Colon Adenocarcinoma PIP5K1A 0.05 0.03 blup 35 0.04 4.0e-03 -6.8 -6.7 1.7e-11 -0.19 0.03 0.82 FALSE
53 The Cancer Genome Atlas Esophageal Carcinoma PIP5K1A 0.10 0.06 lasso 1 0.04 2.1e-02 -5.9 -6.0 2.7e-09 -0.16 0.03 0.13 TRUE
54 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma GOLPH3L 0.12 0.16 blup 49 0.16 4.8e-18 -4.7 5.5 3.4e-08 0.07 1.00 0.00 FALSE
55 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PSMB4 0.03 0.00 blup 37 0.02 7.0e-03 -5.4 7.6 2.6e-14 0.13 0.05 0.38 FALSE
56 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SV2A 0.05 0.02 blup 9 0.03 2.5e-04 -10.8 10.3 8.7e-25 0.48 0.03 0.08 FALSE
57 The Cancer Genome Atlas Brain Lower Grade Glioma PIP5K1A 0.02 0.02 lasso 3 0.02 6.2e-03 -6.8 -6.9 6.1e-12 -0.19 0.04 0.63 FALSE
58 The Cancer Genome Atlas Brain Lower Grade Glioma SV2A 0.04 0.00 blup 9 0.03 5.5e-04 -10.3 -9.3 1.7e-20 -0.21 0.00 0.33 TRUE
59 The Cancer Genome Atlas Liver Hepatocellular Carcinoma MTMR11 0.12 0.09 blup 11 0.10 1.3e-05 -10.8 -6.5 1.1e-10 -0.18 0.07 0.11 FALSE
60 The Cancer Genome Atlas Lung Adenocarcinoma PIP5K1A 0.03 0.01 blup 36 0.02 5.1e-03 -6.3 -6.1 1.0e-09 -0.13 0.06 0.32 TRUE
61 The Cancer Genome Atlas Lung Squamous Cell Carcinoma MRPS21 0.04 0.03 blup 15 0.04 4.0e-05 1.9 -5.2 2.1e-07 0.02 0.09 0.03 FALSE
62 The Cancer Genome Atlas Prostate Adenocarcinoma ARNT 0.06 0.02 lasso 3 0.02 1.4e-03 5.5 -5.4 7.1e-08 -0.05 0.02 0.92 FALSE
63 The Cancer Genome Atlas Prostate Adenocarcinoma ENSA 0.02 0.01 enet 3 0.01 2.5e-02 -4.7 6.7 2.1e-11 0.08 0.01 0.68 FALSE
64 The Cancer Genome Atlas Prostate Adenocarcinoma MTMR11 0.02 0.02 lasso 3 0.02 3.7e-03 -10.4 -10.5 6.0e-26 -0.30 0.03 0.03 FALSE
65 The Cancer Genome Atlas Prostate Adenocarcinoma SF3B4 0.03 0.02 blup 10 0.01 1.4e-02 -10.4 -11.4 3.7e-30 -0.32 0.04 0.16 FALSE
66 The Cancer Genome Atlas Prostate Adenocarcinoma SV2A 0.11 0.10 blup 9 0.11 3.8e-11 -3.1 7.5 7.9e-14 0.40 1.00 0.00 FALSE
67 The Cancer Genome Atlas Skin Cutaneous Melanoma FCGR1A 0.10 0.03 lasso 4 0.04 3.9e-02 -10.8 8.6 7.7e-18 0.38 0.01 0.07 FALSE
68 The Cancer Genome Atlas Stomach Adenocarcinoma POGZ 0.04 0.01 blup 43 0.01 3.7e-02 -5.0 -5.6 2.5e-08 0.02 0.03 0.18 FALSE
69 The Cancer Genome Atlas Thyroid Carcinoma PIP5K1A 0.04 0.06 lasso 2 0.05 9.7e-06 -6.1 -6.2 7.4e-10 -0.15 0.24 0.72 FALSE
70 The Cancer Genome Atlas Thyroid Carcinoma SELENBP1 0.06 0.02 enet 7 0.05 2.3e-05 -5.4 -7.8 7.7e-15 -0.13 0.12 0.81 TRUE