[Hub]/) : Traits : Impedance of arm (left) : ← →

chr1:109,154,974-110,742,615

Best TWAS P=8.17e-10 · Best GWAS P=1.47e-09 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Brain Cerebellar Hemisphere	SYPL2	0.28	0.04	lasso	5	0.09	2.7e-03	-5.5	-5.2	2.2e-07	0.90	0.06	0.88	FALSE
2	GTEx	Brain Cerebellum	SYPL2	0.16	0.02	enet	9	0.03	5.1e-02	-5.4	-5.6	2.2e-08	0.92	0.04	0.88	FALSE
3	GTEx	Colon Sigmoid	SYPL2	0.15	0.06	enet	16	0.06	5.2e-03	-5.5	-5.8	5.3e-09	0.76	0.09	0.81	FALSE
4	GTEx	Liver	SYPL2	0.34	0.27	lasso	5	0.30	4.6e-09	-5.5	-6.0	1.5e-09	0.88	0.04	0.95	FALSE
5	GTEx	Liver	ATXN7L2	0.39	0.04	lasso	12	0.21	1.3e-06	-5.9	-5.4	5.9e-08	0.74	0.04	0.88	FALSE
6	GTEx	Lung	SYPL2	0.24	0.20	enet	16	0.28	1.6e-21	-5.5	-5.2	1.6e-07	0.84	0.22	0.78	FALSE
7	GTEx	Muscle Skeletal	SYPL2	0.20	0.21	lasso	2	0.21	1.5e-20	-5.2	-5.2	1.8e-07	0.77	0.62	0.38	FALSE
8	GTEx	Muscle Skeletal	CYB561D1	0.07	0.00	lasso	3	0.00	7.2e-01	-6.0	5.9	3.5e-09	-0.99	0.03	0.91	FALSE
9	GTEx	Ovary	SYPL2	0.39	0.44	lasso	5	0.46	8.8e-13	-6.0	5.9	4.0e-09	-0.97	0.03	0.97	FALSE
10	GTEx	Ovary	ATXN7L2	0.18	0.18	enet	17	0.13	5.6e-04	-6.0	6.1	8.2e-10	-0.99	0.03	0.94	TRUE
11	GTEx	Pancreas	SYPL2	0.28	0.23	lasso	5	0.19	2.0e-08	-5.5	-5.8	6.0e-09	0.92	0.05	0.95	FALSE
12	GTEx	Stomach	SYPL2	0.23	0.18	lasso	8	0.21	2.3e-10	-5.5	-5.8	5.7e-09	0.90	0.04	0.96	FALSE
13	GTEx	Testis	SORT1	0.25	0.17	lasso	6	0.17	5.2e-08	-5.5	-5.1	2.7e-07	0.84	0.08	0.91	FALSE
14	GTEx	Testis	SYPL2	0.45	0.50	enet	22	0.54	5.0e-28	-5.8	6.0	2.2e-09	-0.99	0.03	0.97	FALSE
15	GTEx	Testis	ATXN7L2	0.28	0.34	lasso	4	0.33	3.7e-15	-5.9	5.9	3.2e-09	-0.99	0.02	0.98	FALSE
16	GTEx	Thyroid	ATXN7L2	0.15	0.15	lasso	6	0.15	1.0e-11	-5.2	5.2	2.3e-07	-0.76	0.37	0.63	FALSE
17	METSIM	Adipose	SYPL2	0.06	0.06	blup	418	0.05	4.3e-08	-5.2	-6.0	1.6e-09	0.80	0.34	0.66	FALSE
18	NTR	Blood	SORT1	0.05	0.06	lasso	6	0.06	2.1e-17	-6.0	-6.1	1.4e-09	0.98	0.02	0.98	FALSE
19	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	SYPL2	0.03	0.05	lasso	4	0.05	6.6e-06	-5.8	-6.0	2.6e-09	0.98	0.01	0.99	FALSE
20	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	SYPL2	0.04	0.04	blup	45	0.04	3.6e-03	-5.4	5.2	2.2e-07	-0.88	0.02	0.59	FALSE
21	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	MYBPHL	0.09	0.07	blup	46	0.06	5.7e-04	-5.5	-6.1	1.3e-09	0.81	0.01	0.77	FALSE
22	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	SYPL2	0.18	0.19	blup	45	0.18	4.7e-09	-5.9	-5.8	7.3e-09	0.95	0.01	0.99	FALSE
23	The Cancer Genome Atlas	Lung Adenocarcinoma	SYPL2	0.09	0.14	enet	13	0.14	1.3e-16	-5.6	-5.3	1.1e-07	0.88	0.04	0.96	FALSE
24	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	SYPL2	0.05	0.06	blup	45	0.06	4.4e-07	-5.8	-5.2	2.6e-07	0.90	0.02	0.98	FALSE
25	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	AMIGO1	0.06	0.00	blup	46	0.02	9.5e-03	-4.5	-5.1	2.8e-07	0.68	0.03	0.29	FALSE
26	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	MYBPHL	0.16	0.18	enet	10	0.17	2.3e-11	-6.0	-6.1	9.3e-10	0.99	0.01	0.99	FALSE
27	The Cancer Genome Atlas	Prostate Adenocarcinoma	SYPL2	0.08	0.08	blup	44	0.10	1.9e-10	-5.5	-5.8	6.3e-09	0.92	0.04	0.96	FALSE
28	The Cancer Genome Atlas	Stomach Adenocarcinoma	CELSR2	0.08	0.00	blup	62	0.02	8.1e-03	-6.0	-6.0	2.7e-09	0.61	0.01	0.41	FALSE
29	The Cancer Genome Atlas	Stomach Adenocarcinoma	SORT1	0.04	0.01	blup	60	0.03	4.4e-03	-3.1	-5.4	7.6e-08	0.75	0.02	0.31	FALSE
30	The Cancer Genome Atlas	Thyroid Carcinoma	ATXN7L2	0.06	0.06	lasso	3	0.05	6.6e-06	-5.5	5.6	2.1e-08	-0.94	0.02	0.97	FALSE