[Hub]/) : Traits : Impedance of arm (left) :

chr1:109,154,974-110,742,615

Best TWAS P=8.17e-10 · Best GWAS P=1.47e-09 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Cerebellar Hemisphere SYPL2 0.28 0.04 lasso 5 0.09 2.7e-03 -5.5 -5.2 2.2e-07 0.90 0.06 0.88 FALSE
2 GTEx Brain Cerebellum SYPL2 0.16 0.02 enet 9 0.03 5.1e-02 -5.4 -5.6 2.2e-08 0.92 0.04 0.88 FALSE
3 GTEx Colon Sigmoid SYPL2 0.15 0.06 enet 16 0.06 5.2e-03 -5.5 -5.8 5.3e-09 0.76 0.09 0.81 FALSE
4 GTEx Liver SYPL2 0.34 0.27 lasso 5 0.30 4.6e-09 -5.5 -6.0 1.5e-09 0.88 0.04 0.95 FALSE
5 GTEx Liver ATXN7L2 0.39 0.04 lasso 12 0.21 1.3e-06 -5.9 -5.4 5.9e-08 0.74 0.04 0.88 FALSE
6 GTEx Lung SYPL2 0.24 0.20 enet 16 0.28 1.6e-21 -5.5 -5.2 1.6e-07 0.84 0.22 0.78 FALSE
7 GTEx Muscle Skeletal SYPL2 0.20 0.21 lasso 2 0.21 1.5e-20 -5.2 -5.2 1.8e-07 0.77 0.62 0.38 FALSE
8 GTEx Muscle Skeletal CYB561D1 0.07 0.00 lasso 3 0.00 7.2e-01 -6.0 5.9 3.5e-09 -0.99 0.03 0.91 FALSE
9 GTEx Ovary SYPL2 0.39 0.44 lasso 5 0.46 8.8e-13 -6.0 5.9 4.0e-09 -0.97 0.03 0.97 FALSE
10 GTEx Ovary ATXN7L2 0.18 0.18 enet 17 0.13 5.6e-04 -6.0 6.1 8.2e-10 -0.99 0.03 0.94 TRUE
11 GTEx Pancreas SYPL2 0.28 0.23 lasso 5 0.19 2.0e-08 -5.5 -5.8 6.0e-09 0.92 0.05 0.95 FALSE
12 GTEx Stomach SYPL2 0.23 0.18 lasso 8 0.21 2.3e-10 -5.5 -5.8 5.7e-09 0.90 0.04 0.96 FALSE
13 GTEx Testis SORT1 0.25 0.17 lasso 6 0.17 5.2e-08 -5.5 -5.1 2.7e-07 0.84 0.08 0.91 FALSE
14 GTEx Testis SYPL2 0.45 0.50 enet 22 0.54 5.0e-28 -5.8 6.0 2.2e-09 -0.99 0.03 0.97 FALSE
15 GTEx Testis ATXN7L2 0.28 0.34 lasso 4 0.33 3.7e-15 -5.9 5.9 3.2e-09 -0.99 0.02 0.98 FALSE
16 GTEx Thyroid ATXN7L2 0.15 0.15 lasso 6 0.15 1.0e-11 -5.2 5.2 2.3e-07 -0.76 0.37 0.63 FALSE
17 METSIM Adipose SYPL2 0.06 0.06 blup 418 0.05 4.3e-08 -5.2 -6.0 1.6e-09 0.80 0.34 0.66 FALSE
18 NTR Blood SORT1 0.05 0.06 lasso 6 0.06 2.1e-17 -6.0 -6.1 1.4e-09 0.98 0.02 0.98 FALSE
19 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma SYPL2 0.03 0.05 lasso 4 0.05 6.6e-06 -5.8 -6.0 2.6e-09 0.98 0.01 0.99 FALSE
20 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma SYPL2 0.04 0.04 blup 45 0.04 3.6e-03 -5.4 5.2 2.2e-07 -0.88 0.02 0.59 FALSE
21 The Cancer Genome Atlas Liver Hepatocellular Carcinoma MYBPHL 0.09 0.07 blup 46 0.06 5.7e-04 -5.5 -6.1 1.3e-09 0.81 0.01 0.77 FALSE
22 The Cancer Genome Atlas Liver Hepatocellular Carcinoma SYPL2 0.18 0.19 blup 45 0.18 4.7e-09 -5.9 -5.8 7.3e-09 0.95 0.01 0.99 FALSE
23 The Cancer Genome Atlas Lung Adenocarcinoma SYPL2 0.09 0.14 enet 13 0.14 1.3e-16 -5.6 -5.3 1.1e-07 0.88 0.04 0.96 FALSE
24 The Cancer Genome Atlas Lung Squamous Cell Carcinoma SYPL2 0.05 0.06 blup 45 0.06 4.4e-07 -5.8 -5.2 2.6e-07 0.90 0.02 0.98 FALSE
25 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma AMIGO1 0.06 0.00 blup 46 0.02 9.5e-03 -4.5 -5.1 2.8e-07 0.68 0.03 0.29 FALSE
26 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma MYBPHL 0.16 0.18 enet 10 0.17 2.3e-11 -6.0 -6.1 9.3e-10 0.99 0.01 0.99 FALSE
27 The Cancer Genome Atlas Prostate Adenocarcinoma SYPL2 0.08 0.08 blup 44 0.10 1.9e-10 -5.5 -5.8 6.3e-09 0.92 0.04 0.96 FALSE
28 The Cancer Genome Atlas Stomach Adenocarcinoma CELSR2 0.08 0.00 blup 62 0.02 8.1e-03 -6.0 -6.0 2.7e-09 0.61 0.01 0.41 FALSE
29 The Cancer Genome Atlas Stomach Adenocarcinoma SORT1 0.04 0.01 blup 60 0.03 4.4e-03 -3.1 -5.4 7.6e-08 0.75 0.02 0.31 FALSE
30 The Cancer Genome Atlas Thyroid Carcinoma ATXN7L2 0.06 0.06 lasso 3 0.05 6.6e-06 -5.5 5.6 2.1e-08 -0.94 0.02 0.97 FALSE