[Hub]/) : Traits : Impedance of arm (left) : ← →

chr1:149,672,809-152,126,467

Best TWAS P=1.52e-50 · Best GWAS P=1.98e-71 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
7	GTEx	Artery Tibial	RP11-196G18.22	0.25	0.05	lasso	5	0.07	1.8e-06	11.7	15.0	1.5e-50	0.78	0.01	0.98	TRUE
36	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SV2A	0.05	0.02	blup	9	0.03	2.5e-04	-10.3	9.9	6.3e-23	0.48	0.03	0.07	TRUE
4	GTEx	Artery Aorta	RPRD2	0.08	-0.01	enet	19	0.00	4.2e-01	-4.9	9.3	1.1e-20	0.30	0.08	0.26	TRUE
20	GTEx	Thyroid	MTMR11	0.09	0.05	enet	9	0.06	1.5e-05	-10.3	-9.0	2.8e-19	-0.40	0.26	0.42	TRUE
28	YFS	Blood	MCL1	0.07	0.03	bslmm	278	0.03	4.4e-10	6.0	-7.6	3.8e-14	-0.10	0.74	0.26	TRUE
49	The Cancer Genome Atlas	Thyroid Carcinoma	SELENBP1	0.06	0.02	enet	7	0.05	2.3e-05	-4.7	-6.5	5.9e-11	-0.13	0.05	0.91	TRUE
16	GTEx	Skin Sun Exposed Lower leg	GABPB2	0.12	0.01	enet	16	0.04	1.8e-04	6.7	-6.1	9.9e-10	-0.03	0.08	0.50	TRUE
23	METSIM	Adipose	POGZ	0.06	0.05	lasso	12	0.03	9.3e-06	-4.7	-5.6	2.1e-08	-0.05	0.99	0.00	TRUE
2	GTEx	Adipose Subcutaneous	RP11-196G18.22	0.13	0.02	enet	16	0.06	6.4e-06	1.2	5.5	3.6e-08	0.44	0.10	0.15	TRUE
10	GTEx	Brain Hippocampus	ARNT	0.14	0.09	enet	14	0.08	5.3e-03	-3.2	-5.2	1.9e-07	0.00	0.10	0.14	TRUE
34	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	GOLPH3L	0.12	0.16	blup	49	0.16	4.8e-18	-4.4	5.1	2.7e-07	0.07	1.00	0.00	TRUE
6	GTEx	Artery Tibial	HIST2H2AA3	0.22	0.02	enet	20	0.12	1.8e-09	16.6	14.2	9.5e-46	0.70	0.00	1.00	FALSE
8	GTEx	Artery Tibial	RP11-196G18.24	0.31	0.08	enet	26	0.10	6.1e-08	16.6	12.8	3.1e-37	0.72	0.00	0.99	FALSE
11	GTEx	Esophagus Muscularis	BOLA1	0.07	0.00	lasso	4	0.00	2.5e-01	-10.3	11.8	5.9e-32	0.43	0.03	0.13	FALSE
45	The Cancer Genome Atlas	Prostate Adenocarcinoma	SF3B4	0.03	0.02	blup	10	0.01	1.4e-02	-9.9	-11.0	2.4e-28	-0.32	0.04	0.16	FALSE
22	GTEx	Thyroid	ANP32E	0.08	0.00	enet	15	0.01	8.6e-02	-7.2	11.0	2.6e-28	0.37	0.04	0.11	FALSE
1	GTEx	Adipose Subcutaneous	MTMR11	0.08	0.04	lasso	4	0.05	3.5e-05	-9.9	-10.8	2.1e-27	-0.37	0.78	0.03	FALSE
44	The Cancer Genome Atlas	Prostate Adenocarcinoma	MTMR11	0.02	0.02	lasso	3	0.02	3.7e-03	-9.9	-10.0	1.0e-23	-0.30	0.03	0.03	FALSE
14	GTEx	Lung	MTMR11	0.08	0.04	lasso	8	0.03	3.0e-03	-9.9	-9.6	6.1e-22	-0.29	0.19	0.11	FALSE
12	GTEx	Heart Left Ventricle	MTMR11	0.11	0.05	lasso	3	0.05	9.3e-04	-10.3	-9.2	3.4e-20	-0.39	0.20	0.13	FALSE
38	The Cancer Genome Atlas	Brain Lower Grade Glioma	SV2A	0.04	0.00	blup	9	0.03	5.5e-04	-9.5	-9.1	8.8e-20	-0.21	0.00	0.33	FALSE
47	The Cancer Genome Atlas	Skin Cutaneous Melanoma	FCGR1A	0.10	0.03	lasso	4	0.04	3.9e-02	-10.3	8.1	4.4e-16	0.38	0.01	0.06	FALSE
15	GTEx	Skin Sun Exposed Lower leg	MTMR11	0.03	0.01	lasso	5	0.00	1.2e-01	-10.3	-8.0	1.1e-15	-0.39	0.05	0.05	FALSE
27	METSIM	Adipose	TMOD4	0.02	0.00	blup	312	0.01	3.2e-02	-7.1	7.8	7.5e-15	0.11	0.03	0.65	FALSE
46	The Cancer Genome Atlas	Prostate Adenocarcinoma	SV2A	0.11	0.10	blup	9	0.11	3.8e-11	-2.9	7.3	3.8e-13	0.40	1.00	0.00	FALSE
32	The Cancer Genome Atlas	Breast Invasive Carcinoma	SV2A	0.03	0.02	enet	3	0.02	8.0e-06	-2.9	6.9	5.7e-12	0.38	0.13	0.23	FALSE
43	The Cancer Genome Atlas	Prostate Adenocarcinoma	ENSA	0.02	0.01	enet	3	0.01	2.5e-02	-4.4	6.7	2.1e-11	0.08	0.00	0.76	FALSE
35	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PSMB4	0.03	0.00	blup	37	0.02	7.0e-03	-4.7	6.7	2.4e-11	0.13	0.02	0.60	FALSE
25	METSIM	Adipose	RP11-196G18.24	0.27	0.01	blup	116	0.13	3.6e-19	3.2	6.5	6.1e-11	0.31	0.04	0.94	FALSE
26	METSIM	Adipose	SCNM1	0.06	0.06	lasso	10	0.05	3.6e-08	5.9	6.3	2.9e-10	0.14	0.71	0.29	FALSE
30	YFS	Blood	SCNM1	0.09	0.04	enet	62	0.08	1.3e-24	-5.2	6.2	4.5e-10	0.05	0.98	0.02	FALSE
29	YFS	Blood	PRUNE	0.05	0.00	enet	33	0.02	5.8e-06	-3.3	-6.1	1.2e-09	-0.06	0.10	0.22	FALSE
33	The Cancer Genome Atlas	Colon Adenocarcinoma	PIP5K1A	0.05	0.03	blup	35	0.04	4.0e-03	-5.8	-5.9	2.8e-09	-0.19	0.09	0.52	FALSE
18	GTEx	Spleen	RP11-54A4.2	0.29	0.10	lasso	9	0.04	3.8e-02	-5.7	5.9	3.0e-09	0.04	0.31	0.04	FALSE
5	GTEx	Artery Tibial	ARNT	0.09	0.07	lasso	3	0.06	1.5e-05	6.0	-5.9	3.3e-09	-0.07	0.14	0.80	FALSE
41	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	MRPS21	0.04	0.03	blup	15	0.04	4.0e-05	2.6	-5.8	4.8e-09	0.02	0.08	0.14	FALSE
37	The Cancer Genome Atlas	Brain Lower Grade Glioma	PIP5K1A	0.02	0.02	lasso	3	0.02	6.2e-03	-5.8	-5.8	5.0e-09	-0.19	0.09	0.09	FALSE
17	GTEx	Skin Sun Exposed Lower leg	SV2A	0.07	0.00	enet	15	0.02	6.0e-03	-2.8	-5.8	8.1e-09	-0.16	0.07	0.12	FALSE
39	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	MTMR11	0.12	0.09	blup	11	0.10	1.3e-05	-10.3	-5.8	8.6e-09	-0.18	0.08	0.07	FALSE
21	GTEx	Thyroid	PRUNE	0.11	0.00	enet	21	0.03	3.1e-03	-1.6	-5.6	2.6e-08	-0.07	0.42	0.02	FALSE
42	The Cancer Genome Atlas	Prostate Adenocarcinoma	ARNT	0.06	0.02	lasso	3	0.02	1.4e-03	6.0	-5.6	2.6e-08	-0.05	0.00	0.98	FALSE
24	METSIM	Adipose	PSMD4	0.03	0.05	lasso	4	0.04	6.1e-07	-5.2	5.5	2.9e-08	0.22	0.96	0.03	FALSE
19	GTEx	Stomach	CTSS	0.05	0.02	enet	16	0.00	2.8e-01	-4.0	-5.5	3.2e-08	-0.01	0.08	0.70	FALSE
40	The Cancer Genome Atlas	Lung Adenocarcinoma	PIP5K1A	0.03	0.01	blup	36	0.02	5.1e-03	-5.7	-5.5	3.2e-08	-0.13	0.09	0.04	FALSE
31	The Cancer Genome Atlas	Breast Invasive Carcinoma	PIP5K1A	0.04	0.05	lasso	6	0.05	8.8e-10	-5.2	-5.5	4.3e-08	-0.15	0.96	0.04	FALSE
3	GTEx	Adrenal Gland	CTSS	0.12	0.13	lasso	9	0.08	7.0e-04	-5.7	-5.4	6.4e-08	0.00	0.52	0.33	FALSE
13	GTEx	Heart Left Ventricle	CERS2	0.08	0.02	enet	9	0.03	1.7e-02	-4.0	5.4	6.6e-08	0.08	0.18	0.14	FALSE
48	The Cancer Genome Atlas	Thyroid Carcinoma	PIP5K1A	0.04	0.06	lasso	2	0.05	9.7e-06	-5.2	-5.3	1.1e-07	-0.15	0.79	0.06	FALSE
9	GTEx	Brain Cerebellar Hemisphere	RP11-316M1.12	0.31	0.37	lasso	4	0.39	4.5e-11	-4.0	5.2	2.4e-07	0.01	0.99	0.00	FALSE